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Journal articles on the topic 'Eosinophilia and endoscopy'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Cheung, Ka Ming, Mark R. Oliver, Donald J. S. Cameron, Anthony G. Catto‐Smith, and Chung W. Chow. "Esophageal Eosinophilia In Children With Dysphagia." Journal of Pediatric Gastroenterology and Nutrition 37, no. 4 (2003): 498–503. http://dx.doi.org/10.1002/j.1536-4801.2003.tb12045.x.

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ABSTRACTObjectivesChildren occasionally have dysphagia in the absence of an apparent primary cause. Esophageal eosinophilia is sometimes seen in these patients at the time of upper endoscopy but its significance is not clear. Although eosinophilia is regarded by some as a histologic hallmark of childhood reflux esophagitis, it may in fact signal a primary eosinophilic esophagitis in children with dysphagia. Our aim was to evaluate esophagitis, acid reflux determined by pH probe, and esophageal eosinophilia in children with the primary complaint of dysphagia.MethodsA retrospective study was per

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Cristofori, Fernanda, Fulvio Salvatore D’Abramo, Vincenzo Rutigliano, et al. "Esophageal Eosinophilia and Eosinophilic Esophagitis in Celiac Children: A Ten Year Prospective Observational Study." Nutrients 13, no. 11 (2021): 3755. http://dx.doi.org/10.3390/nu13113755.

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The association between eosinophilic esophagitis and celiac disease is still controversial and its prevalence is highly variable. We aimed to investigate the prevalence of esophageal eosinophilia and eosinophilic esophagitis in a large group of children with celiac disease, prospectively followed over 11 years. Methods: Prospective observational study performed between 2008 and 2019. Celiac disease diagnosis was based on ESPGHAN criteria. At least four esophageal biopsies were sampled in patients who underwent endoscopy. The presence of at least 15 eosinophils/HPF on esophageal biopsies was co

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Azizullah, Azizullah, Arslan Shahzad, Hina Shaukat, and Rashad Mahmood. "Prevalence of esophageal eosinophilia in patients referred for diagnostic upper gastrointestinal endoscopy." International journal of health sciences 7, S1 (2023): 1119–26. http://dx.doi.org/10.53730/ijhs.v7ns1.14326.

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Background and Aim: Esophageal eosinophilia such as gastro-esophageal reflux disease (GERD) and eosinophilic esophagitis (EoE) are associated with several conditions. Esophagus eosinophilic infiltration characterized the Eosinophilic esophagitis (EoE). The purpose of the present study was to determine the esophageal eosinophilia prevalence in patients underwent diagnostic upper gastrointestinal endoscopy. Patients and Methods: This cross-sectional study was carried out on 96 male adult patients underwent upper gastrointestinal endoscopy for unexplained upper GI symptoms in the department of He

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Nguyen Dang Huynh, Trong, Thong Quang Pham, Quyen Thi Trieu Pham, and Phat Tan Ho. "Eosinophilic gastrointestinal disorders presenting with multiple gastric and colonic ulcerative lesions: a case report." MedPharmRes 6, no. 3 (2022): s33—s37. http://dx.doi.org/10.32895/ump.mpr.6.3.s7.

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Eosinophilic gastrointestinal disorders are rare inflammatory conditions marked by eosinophilic infiltration of the gastrointestinal tract. Endoscopic manifestations vary from patient to patient. However, ulcerative lesion is a rare occurence. A 57-year-old patient presented with chronic diarrhea and significant peripheral blood eosinophilia. During endoscopy, multiple ulcers were discovered throughout the stomach, duodenum, and colon. Biopsies showed excess tissue eosinophilia suggestive of eosinophilic gastroenteritis and colitis. The patient responded dramatically with corticosteroid. Howev

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Ruchelli, Eduardo, William Wenner, Theresa Voytek, Kurt Brown, and Chris Liacouras. "Severity of Esophageal Eosinophilia Predicts Response to Conventional Gastroesophageal Reflux Therapy." Pediatric and Developmental Pathology 2, no. 1 (1999): 15–18. http://dx.doi.org/10.1007/s100249900084.

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Pediatric patients who present with symptoms of gastroesophageal reflux and severe eosinophilic esophagitis may be unresponsive to aggressive anti-reflux medical therapy. In order to determine whether the degree of eosinophilia predicts anti-reflux treatment response and possibly distinguishes different etiologies, we reviewed the initial biopsies of patients with esophageal eosinophilia and compared the number of eosinophils with the response to anti-reflux treatment. Over a 1-year period, 102 patients with a biopsy demonstrating at least 1 intraepithelial eosinophil were identified among pat

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Tosca, Maria Angela, Donata Girosi, Oliviero Sacco, Roberto Bernardini, and Giorgio Ciprandi. "Steroid-sparing effect of mepolizumab in children with severe eosinophilic nonallergic asthma." Allergologia et Immunopathologia 49, no. 5 (2021): 113–16. http://dx.doi.org/10.15586/aei.v49i5.466.

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Background: Asthma is characterized by a chronic airway inflammation, usually sustained by type 2 immunity. Bronchial and peripheral eosinophilia are biomarkers for type 2 asthma. Biologicals are the most effective treatment for severe asthma at present. Mepolizumab is an antagonist of interleukin-5 (IL-5), the most relevant cytokine involved in eosinophilia.Objective: This case report evaluated the effectiveness of mepolizumab in two girls with severe eosinophilic non-allergic asthma.Materials and methods: Two female children with severe eosinophilic nonallergic asthma were treated with mepol

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Eladely, A., and K. Roncin. "Eosinophilic gastroenteritis, a rare case report and literature review." American Journal of Clinical Pathology 162, Supplement_1 (2024): S44. http://dx.doi.org/10.1093/ajcp/aqae129.096.

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Abstract Introduction/Objective Eosinophilic gastroenteritis (EGE) is a rare inflammatory condition affecting the gastrointestinal tract, initially described by Kaijser et al. in 1937. It manifests as eosinophil-rich infiltration throughout the GI tract, often accompanied by peripheral eosinophilia. EGE is categorized under eosinophilic gastrointestinal disorders (EGIDs), alongside eosinophilic esophagitis (EOE) and eosinophilic colitis (EC). Symptoms vary based on the affected GI segment. This report aims to present a case of extensive EGE in a young male patient and review of similar cases t

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Warners, Marijn J., Bram D. van Rhijn, Joanne Verheij, Andreas J. P. M. Smout, and Albert J. Bredenoord. "Disease activity in eosinophilic esophagitis is associated with impaired esophageal barrier integrity." American Journal of Physiology-Gastrointestinal and Liver Physiology 313, no. 3 (2017): G230—G238. http://dx.doi.org/10.1152/ajpgi.00058.2017.

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In eosinophilic esophagitis (EoE), the esophageal barrier integrity is impaired. Integrity can be assessed with different techniques. To assess the correlations between esophageal eosinophilia and various measures of mucosal integrity and to evaluate whether endoscopic impedance measurements can predict disease activity, endoscopies and mucosal integrity measurements were performed in adult EoE patients with active disease (≥15 eosinophils/high-power field) at baseline ( n = 32) and after fluticasone ( n = 15) and elemental dietary treatment ( n = 14) and in controls ( n = 19). Mucosal integri

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CARRASCO, Adriana Elisabeth Aguiar Benavides, Rodrigo Strehl MACHADO, Francy Reis da Silva PATRÍCIO, and Elisabete KAWAKAMI. "HISTOLOGICAL FEATURES OF EOSINOPHILIC ESOPHAGITIS IN CHILDREN AND ADOLESCENTS." Arquivos de Gastroenterologia 54, no. 4 (2017): 281–85. http://dx.doi.org/10.1590/s0004-2803.201700000-44.

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ABSTRACT BACKGROUND: Eosinophilic esophagitis is an emerging disease featured by eosinophilic esophageal infiltrate not responsive to proton pump inhibitors. OBJECTIVE: To characterize histological features of children and adolescents with eosinophilic esophagitis. METHODS: Cross-sectional study in a tertiary hospital. Biopsies from each esophageal third from 14 patients (median age 7 years) with eosinophilic esophagitis were evaluated. Histological features evaluated included morphometry of esophageal epithelium, esophageal density (per high power field), extracellular eosinophilic granules,

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Maleki, Nasrollah, Mohammadreza Kalantar Hormozi, Mehrzad Bahtouee, Zahra Tavosi, Hamidreza Mosallai Pour, and Seiiedeh Samaneh Taghiyan Jamaleddin Kolaii. "Eosinophilic Ascites and Duodenal Obstruction in a Patient with Liver Cirrhosis." Case Reports in Gastrointestinal Medicine 2014 (2014): 1–4. http://dx.doi.org/10.1155/2014/928496.

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Eosinophilic gastroenteritis (EG) is a rare disease characterized by eosinophilic infiltration of portions of the gastrointestinal tract. Eosinophilic ascites is probably the most unusual and rare presentation of EG and is generally associated with the serosal form of EG. Hereby, we report a case of eosinophilic ascites with duodenal obstruction in a patient with liver cirrhosis. A 50-year-old woman was admitted to our hospital because of abdominal pain, nausea, bloating, and constipation. She had a history of laparotomy because of duodenal obstruction 2 years ago. Based on clinical, radiologi

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Priyadharshini, V., K. I. S. N. Vaishnavi, N. Krishna Geetha, and Shankar A. Gowri. "Inflammatory synergy: a rare encounter of eosinophilic esophagitis and acute gastritis." Romanian Journal of Medical Practice 19, no. 3 (2024): 301–5. http://dx.doi.org/10.37897/rjmp.2024.3.14.

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Eosinophilic Esophagitis (EoE) is a chronic, antigen-mediated esophageal disease characterized by eosinophil-predominant inflammation, typically identified in younger individuals, particularly white males between 30 and 40 years of age. However, this case report discusses an unusual presentation of EoE in a 65-year-old female with a history of allergic rhinitis. The patient presented with symptoms of heartburn, epigastric pain, dysphagia, nausea, vomiting, and abdominal bloating, which had been occurring intermittently over the past two years. Investigations revealed significant eosinophilia,

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Farrell, Nyssa F., Jess C. Mace, David A. Sauer, et al. "Mucosal Eosinophilia and Neutrophilia Are Not Associated With QOL or Olfactory Function in Chronic Rhinosinusitis." American Journal of Rhinology & Allergy 35, no. 5 (2021): 647–55. http://dx.doi.org/10.1177/1945892420987439.

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Background Chronic rhinosinusitis (CRS) is often differentiated by histopathologic phenotypes (eosinophilic versus neutrophilic), which may impact disease severity measures and outcomes. As such, it has been suggested that counts of cellular elements be included as part of a standard pathological report following endoscopic sinus surgery (ESS). Objectives This cross-sectional study evaluated associations of mucosal eosinophilia and neutrophilia with measures of quality-of-life (QoL) and olfactory function. Methods Patients with medically refractory CRS completed the SNOT-22 survey and Brief Sm

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Kasinathan, Ganesh, and Jameela Sathar. "Ascites in a young male: idiopathic FIP1L1-PDGFRA-negative hypereosinophilic syndrome." JRSM Open 11, no. 1 (2020): 205427041989482. http://dx.doi.org/10.1177/2054270419894826.

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Introduction Idiopathic hypereosinophilic syndrome is defined as persistently elevated peripheral blood absolute eosinophil count of more than 1.5 × 109/L for at least six months with no obvious secondary cause. Case Presentation We report the case of a 26-year-old gentleman of Malay ethnicity who presented to the medical department with a three-week history of abdominal distension associated with dyspepsia and epigastric pain. Physical examination revealed ascites. The complete blood count portrayed peripheral leucocytosis with eosinophilia of 8.84 × 109/L. Parasitic serology was negative. Pa

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Sasaki, Yu, Yasuhiko Abe, Naoko Mizumoto, Eiki Nomura, and Yoshiyuki Ueno. "Small Bowel Endoscopic Features of Eosinophilic Gastroenteritis." Diagnostics 13, no. 1 (2022): 113. http://dx.doi.org/10.3390/diagnostics13010113.

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Eosinophilic gastroenteritis (EoGE) is a rare digestive disorder characterized by eosinophilic infiltration of the stomach and intestines. In the diagnosis of EoE, it is extremely important to recognize distinctive endoscopic findings and accurately detect increased eosinophilia in gastrointestinal tissues. However, endoscopic findings of EoGE in the small intestine remain poorly understood. Therefore, we conducted a literature review of 16 eligible papers. Redness or erythema was the most common endoscopic finding in the small bowel, followed by villous atrophy, erosion, ulceration, and edema

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Chundempetta, Daniyah C. H., and R. Legha. "A case report of eosinophilic enterocolitis." International Journal of Research in Medical Sciences 11, no. 10 (2023): 3859–61. http://dx.doi.org/10.18203/2320-6012.ijrms20233046.

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A 13-year-old boy was admitted with complaints of abdominal pain and loose stools. Abdomen was distended. Laboratory tests on admission revealed neutrophilic leukocytosis and a peripheral smear done showed severe eosinophilia (33%) and leukocytosis. CT abdomen revealed ascites. Ascitic fluid tapping was done and 1.5 L of straw colored ascitic fluid drained. Ascitic fluid study was suggestive of high protein low SAAG ascites. The possibility of eosinophilic enterocolitis was considered. For confirmation endoscopy and sigmoidoscopy were done and a segmental biopsy was taken. Biopsy was suggestiv

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Bleibel, Fadi, Keith Fragoza, and Garrey T. Faller. "Acute Eosinophilic Ascites in a Middle-Aged Man." Case Reports in Gastrointestinal Medicine 2012 (2012): 1–4. http://dx.doi.org/10.1155/2012/896523.

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Eosinophilic gastroenteritis is a rare condition characterized by recurrent eosinophilic infiltration of portions of the GI tract and presenting with nonspecific GI symptoms in association with peripheral eosinophilia. Its etiology and pathogenesis remain unclear and its symptoms overlap with many GI and systemic diseases. Thus, both gastroenterologists and general internists need to be aware of this rare condition. We present a case of a 55-year-old male with diffuse abdominal pain and distention for two weeks. His physical examination was significant for moderate ascites. Initial work-up dem

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Krarup, Anne Lund, Asbjørn Mohr Drewes, Per Ejstrud, Peter Thaysen Laurberg, and Mogens Vyberg. "Implementation of a biopsy protocol to improve detection of esophageal eosinophilia: a Danish registry-based study." Endoscopy 53, no. 01 (2020): 15–24. http://dx.doi.org/10.1055/a-1206-0852.

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Abstract Background In the North Denmark Region (580 272 inhabitants), only 0–4 cases of possible eosinophilic esophagitis (EoE) were identified annually in 1999–2010, suggesting underdiagnosis. This study aimed to increase the diagnosis of EoE by introducing a regional biopsy protocol for patients with dysphagia. Methods In 2011, leaders of regional endoscopy units attended a consensus meeting where a biopsy protocol was proposed. The national pathology registry was used to identify patients with esophageal eosinophilic inflammation during 2007–2017. Results Discussion resulted in consensus o

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Josué, Isaac Olarte García, Rodriguez Ibarra Moisés, Bautista de la Cruz Alfredo, et al. "Gastrointestinal Eosinophilic Disorder in a Patient with Acute Pancreatitis. Case Report." International Journal Of Medical Science And Clinical Research Studies 03, no. 06 (2023): 1099–103. https://doi.org/10.5281/zenodo.8037549.

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  Eosinophilic colitis is a rare disease. It is part of the eosinophilic gastroenteritis, characterized by eosinophilic infiltration of the tissues that affects any segment of the digestive tract, but more frequently the stomach and small intestine and rarely the colon in isolation. The clinical case of a 29- year-old patient is described, who initially presented data of acute pancreatitis and later acute diarrhea with sluggishness and scant mucus. The analysis showed a complete blood count with eosinophilia 9.9% Immunoglobulin E with a positive result + 2500 IU/mL (<100IU/mL). Endosco

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Wąsik, Jakub, and Ewa Małecka-Wojciesko. "Eosinophilic Esophagitis—What Do We Know So Far?" Journal of Clinical Medicine 12, no. 6 (2023): 2259. http://dx.doi.org/10.3390/jcm12062259.

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Eosinophilic esophagitis is a Th-2 antigen-mediated disease in which there is an influx of eosinophils to all layers of the esophagus, triggering an inflammatory response. Chronic inflammatory process causes esophageal remodeling, leading to difficulties in swallowing. Food impaction, heartburn, and chest pain are other characteristic (but not pathognomonic) symptoms in adults. Although the disease has only been described since in the early 1970s, its incidence and prevalence are rapidly growing, especially in Western countries. According to the diagnostic guidelines, there should be at least

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Abe, Yasuhiko, Yu Sasaki, Makoto Yagi, et al. "Endoscopic Diagnosis of Eosinophilic Esophagitis: Basics and Recent Advances." Diagnostics 12, no. 12 (2022): 3202. http://dx.doi.org/10.3390/diagnostics12123202.

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Eosinophilic esophagitis (EoE) is a chronic, immune-mediated inflammatory disease, characterized by esophageal dysfunction and intense eosinophil infiltration localized in the esophagus. In recent decades, EoE has become a growing concern as a major cause of dysphagia and food impaction in adolescents and adults. EoE is a clinicopathological disease for which the histological demonstration of esophageal eosinophilia is essential for diagnosis. Therefore, the recognition of the characteristic endoscopic features with subsequent biopsy are critical for early definitive diagnosis and treatment, i

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De Matteis, Arianna, Giuseppe Pagliaro, Vito Domenico Corleto, et al. "Eosinophilic Esophagitis in Children: Clinical Findings and Diagnostic Approach." Current Pediatric Reviews 16, no. 3 (2020): 206–14. http://dx.doi.org/10.2174/1573396315666191004110549.

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: Eosinophilic esophagitis (EoE) is an emerging chronic immune and antigen-mediated clinicopathologic disease. During the last 2 decades, the incidence of this condition in children has increased significantly, thanks to practitioners for creating the awareness and higher use of diagnostic endoscopy. We have analysed paediatric literature on EoE focusing on the epidemiology, pathophysiology, clinical findings and diagnostic approach. : EoE is pathogenically related to a Th2 inflammation characterized by a mixed IgE and non-IgEmediated reaction to food and/or environmental agents. This leads to

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Kumar, Kishore, Jasbir Makker, Hassan Tariq, et al. "Co-Occurrence of Rarest Type of Dysphagia Lusoria (Type N-1) and Eosinophilic Esophagitis in a Cognitively Disabled Individual." Case Reports in Medicine 2019 (November 11, 2019): 1–6. http://dx.doi.org/10.1155/2019/2890635.

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Dysphagia is an expressive symptom, described by an individual as “difficulty in swallowing.” Dysphagia due to esophageal compression from an aberrant right subclavian artery is rare, and it is termed as “dysphagia lusoria.” We present a rare case of co-occurrence of dysphagia lusoria with esophageal eosinophilia in a patient with cognitive disability which portends a case with diagnostic challenge and treatment dilemma. A 31-year-old man with intellectual disability, cerebral palsy, previous history of feeding difficulty, and esophageal food impaction presented with esophageal foreign body im

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Hoque, Md Monirul, Shuvojit Sen, and Md Nizam Uddin. "Strongyloidiasis: The Cause of Hypereosinophillia and Duodenal Ulcer in an Immunocompetent Individual." Journal of Armed Forces Medical College, Bangladesh 12, no. 1 (2016): 109–11. http://dx.doi.org/10.3329/jafmc.v12i1.39980.

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Strongyloidiasis is a common parasitic disease in tropical and sub-tropical regions of the world. Infection with Strongyloides Stercoralis usually remains asymptomatic with peripheral eosinophilia and uncontrolled growth. Consequently, immunocompromised individuals are at a higher risk of complications of this disease. A case of an immunocompetent patient who had complaint of acute abdominal pain and was found to have duodenal ulceration. Laboratory examination revealed significantly elevated absolute eosinophil count at 17000/cmm (normal 0-500/cmm). The stool R/E revealed rhabtidiform larvae

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IONIȚĂ, LUCIAN, ALEXANDRA BRAICA, CĂTĂLIN MICȘA, et al. "Canine eosinophilic bronchopneumopathy: case study." Romanian Biotechnological Letters 27, no. 2/2022 (2022): 3460–65. http://dx.doi.org/10.25083/rbl/28.3/3460.3465.

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Eosinophilic bronchopneumopathy, formerly known as PIE (Pulmonary Infiltration with Eosinophils) syn¬drome, is defined as an inflammatory pathology haracterized by the presence of eosinophilic infiltrate in the lungs and bronchiolary structures. (CECILE CLERCX,2007). Canine eosinophilic bronchopneumopathy has been described similarly to that present in humans, highlighting tropism for the airways and lungs, but also the multitude of factors with the potential to trigger, which is why most of them are ranked with idiopathic factor. (Sol Kim et a1,2021). Cases of eosinophilic bronchopneumopathy

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Biazar, Tahmineh, Parisa Sabbagh, Soheil Ebrahimpour, and Masomeh Bayani. "Eosinophilic gastroenteritis with acute abdomen: A case report." Acta Facultatis Medicae Naissensis 38, no. 1 (2021): 96–100. http://dx.doi.org/10.5937/afmnai2101096b.

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Eosinophilic gastroenteritis (EGE) as a rare inflammatory gastrointestinal (GI) disorder is primarily characterized by long-term or recurrent abdominal pain. Peripheral eosinophilia is usually caused by eosinophilic infiltrations into the multiple layers of the GI tract. In this report, a case of EGE with an acute abdomen is presented. A 14-year-old female experienced severe abdominal pain and hypereosinophilia. She underwent appendectomy due to severe abdominal pain approximately one week before readmission. Because of the persistence of pain, the upper GI endoscopy and biopsy were performed

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Hofstaedter, Casey E., Runa Watkins, and Nidhi Kotwal. "Asymptomatic Esophageal Eosinophilia in an 11-Year-Old with Severe Persistent Asthma." Case Reports in Pediatrics 2023 (October 12, 2023): 1–3. http://dx.doi.org/10.1155/2023/6678918.

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Asymptomatic esophageal eosinophilia (aEE) is a rare presentation, where patients have increased eosinophils in esophageal mucosa but lack any esophagus-related symptoms. Cases of aEE have only been documented in adults, and little is known about its clinical significance and whether treatment is warranted. We report a case of an 11-year-old patient with uncontrolled severe persistent asthma who underwent flexible bronchoscopy and upper endoscopy as a part of complete aerodigestive evaluation. Elevated intraepithelial eosinophils in the esophageal mucosa were noted, suggesting an aEE-like pres

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Gremida, A., K. Huang, M. Ciorba, C. Deyali, and P. Deepak. "P584 Mucosal Eosinophilia is an Independent Predictor of Vedolizumab Effectiveness in Ulcerative Colitis." Journal of Crohn's and Colitis 15, Supplement_1 (2021): S537. http://dx.doi.org/10.1093/ecco-jcc/jjab076.705.

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Abstract Background Ulcerative Colitis (UC) is characterized by intestinal inflammation with chronic inflammatory features. Along with the typical neutrophil-predominant inflammation, there has been growing understanding of the role of eosinophils in UC and the potential therapeutic benefit of Vedolizumab (VDZ) in those cases. VDZ blocks gastrointestinal homing of T lymphocytes and eosinophil recruitment to the intestinal mucosa via blocking α4β7 which plays a major role in eosinophils localization to the intestinal mucosa. We aimed to assess whether mucosal eosinophilia can predict response t

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Ganti, Ashwin, Hannah N. Kuhar, Michael Eggerstedt, et al. "The Association of Serum Eosinophilia with Structured Histopathology in Chronic Rhinosinusitis." Annals of Otology, Rhinology & Laryngology 129, no. 5 (2019): 512–16. http://dx.doi.org/10.1177/0003489419898200.

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Background: Prior studies have demonstrated associations between serum eosinophilia and chronic rhinosinusitis (CRS) pathogenesis. However, the association of serum eosinophilia with histopathology profiling in CRS has not been fully delineated and may help better characterize CRS disease burden prior to surgery. Methods: A structured histopathology report of 13 variables was utilized to analyze sinus tissue removed during functional endoscopic sinus surgery (FESS). Complete blood count (CBC) with differential was drawn within 4 weeks prior to FESS. Serum eosinophilia was defined as >6.0% (

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Yamamoto, Takatsugu, Toru Miyazaki, Yukiko Kurashima, et al. "Solitary Hepatic Eosinophilic Granuloma Accompanied by Eosinophilia Without Parasitosis: Report of a Case." International Surgery 100, no. 6 (2015): 1011–17. http://dx.doi.org/10.9738/intsurg-d-14-00126.1.

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A 43-year-old Japanese woman visited for a hepatic tumor incidentally found. We suspected eosinophilic granuloma of the liver (EGL) due to visceral larva migrans (VLM). However, neither past history nor medical interview indicated a risk of parasitosis. Blood testing revealed eosinophilia, serum examination showed normal results for immunoglobulin E, and enzyme-linked immunosorbent assay yielded negative for Toxocara and Anisakis. Gastric and colonic endoscopy revealed normal features. Several imagings showed central necrosis of the tumor. After informed consent, laparoscopic resection was per

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Yousef, Ejaz, Yelena Korotkaya, and Alyson B. Simpson. "Eosinophilic esophagitis in children: Updates and practical aspects of management for allergists in a non‐tertiary care private practice setup." Allergy and Asthma Proceedings 43, no. 1 (2022): 5–11. http://dx.doi.org/10.2500/aap.2022.43.210084.

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Background: Eosinophilic esophagitis (EoE) is a chronic immune and/or antigen-mediated disease characterized by eosinophilic infiltration of mucosa (≥15 eosinophils per high power field) without any secondary etiology. Non‐immunoglobulin E mediated mechanisms predominate in EoE. Objective: This review concentrated on a stepwise approach for the allergist working in non‐tertiary care private practice. Methods: A medical literature search that focused on several areas of the latest developments in the diagnosis and management of EoE was conducted. Results: There has been a steady increase in the

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Schroeder, Jonathan C., David Jones, and Ashley Maranich. "Peripheral Eosinophilia Found in Pediatric Enterobius vermicularis Infections." Clinical Pediatrics 58, no. 1 (2018): 13–16. http://dx.doi.org/10.1177/0009922818805193.

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Enterobius vermicularis, the common pinworm, is well known in North America as a parasitic infection, mainly affecting children. It is a very contagious organism, and it is responsible for a high number of infections in the United States each year. A rise in eosinophilia is linked to most parasitic infections. However, the correlation between eosinophilia and enterobiasis infections is not well documented in the literature. In this article, we present 3 cases involving patients seen for pediatric gastroenterology consultation with concern for inflammatory bowel disease. As part of their evalua

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Watts, Melissa M., Carol Saltoun, and Paul A. Greenberger. "Eosinophilic esophagitis." Allergy and Asthma Proceedings 40, no. 6 (2019): 462–64. http://dx.doi.org/10.2500/aap.2019.40.4272.

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Eosinophilic esophagitis (EoE) is defined by symptoms related to esophageal dysfunction, persistent esophageal eosinophilia, and exclusion of other etiologies that may be contributing to the condition. EoE is different from erosive esophagitis. In children, symptoms vary by age groups, such as feeding disorders in 2 year olds; vomiting in 8 year olds; and abdominal pain, dysphagia, and/or food impaction in adolescents. Most adults present with dysphagia, food impaction, heartburn, or chest pain. Common endoscopic features in adults with EoE include linear furrows (creases that orient longitudi

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Hashimoto, Atsushi, Takashi Sugawa, Narika Iwakura, et al. "The Predictive Factors of Responsiveness to Proton Pump Inhibitor Therapy for Eosinophilic Esophagitis." Gastrointestinal Disorders 1, no. 1 (2019): 220–30. http://dx.doi.org/10.3390/gidisord1010017.

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Approximately half of patients with eosinophilic esophagitis (EoE) respond clinically and histologically to proton pump inhibitor (PPI) therapy. Although recent guidelines suggest that PPI-responders and non-responders were included in EoE, it is important to investigate the predictive factors of PPI- responsiveness. This study aimed to determine the rate of PPI- responders and compare the characteristics of PPI-responders and non-responders. Fifty-nine patients with esophageal eosinophilia received PPI therapy for eight weeks, and its efficacy was assessed. PPI- responsiveness was diagnosed b

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Porfire (Irimia), Ioana Maria, Ioana Berindan-Neagoe, Livia Budisan, et al. "Tissue Interleukin-33: A Novel Potential Regulator of Innate Immunity and Biomarker of Disease Severity in Chronic Rhinosinusitis with Nasal Polyps." Journal of Clinical Medicine 12, no. 24 (2023): 7537. http://dx.doi.org/10.3390/jcm12247537.

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Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a disease of real interest for researchers due to its heterogenicity and complex pathophysiological mechanisms. Identification of the factors that ensure success after treatment represents one of the main challenges in CRSwNP research. No consensus in this direction has been reached so far. Biomarkers for poor outcomes have been noted, but nonetheless, their prognostic value has not been extensively investigated, and needs to be sought. We aimed to evaluate the correlation between potential prognostic predictors for recalcitrant

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Zdanowicz, Katarzyna, Artur Rycyk, Dariusz Marek Lebensztejn, and Urszula Daniluk. "Dysphagia Among Children—A Single-Center Experience." Journal of Clinical Medicine 14, no. 9 (2025): 2906. https://doi.org/10.3390/jcm14092906.

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Background/Objectives: In recent years, there has been an increase in the prevalence of eosinophilic esophagitis (EoE), in which dysphagia is one of the main symptoms. To date, there are few data on the prevalence of EoE in pediatric patients with dysphagia. The aim of this study was to determine the causes of dysphagia in children in our region. The second aim of this study was to estimate the prevalence of EoE in children with swallowing difficulties and to see if there were differences in the characteristics of dysphagia reported by children with EoE compared to children with non-EoE-relate

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Tanaka, Kyosuke, Carlos A. Rubio, Aldona Dlugosz, et al. "Narrow-band imaging magnifying endoscopy in adult patients with eosinophilic esophagitis/esophageal eosinophilia and lymphocytic esophagitis." Gastrointestinal Endoscopy 78, no. 4 (2013): 659–64. http://dx.doi.org/10.1016/j.gie.2013.05.025.

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Patil, Mallikarjun, Keyur A. Sheth, and Harshad Devarbhavi. "Endoscopy in a rare presentation of worms." Journal of Digestive Endoscopy 05, no. 02 (2014): 080–82. http://dx.doi.org/10.4103/0976-5042.144836.

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AbstractUpper gastrointestinal bleeding can be a life threatening complication. Hookworms infestation usually causes chronic blood loss resulting in anemia. A 52 year old male presented to us with massive gastrointestinal blood loss and hemodynamic instability. On examination he had anemia, which on evaluation was iron deficient microcytic hypochromic anemia with eosinophilia. On evaluation of small bowel mucosa showed multiple hookworms moving on the surface. He improved with anthelmintics, blood transfusion and supportive management. The repeat evaluation showed eradication of worms. Hookwor

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Hosaka, Hiroko, Shiko Kuribayashi, Yasuyuki Shimoyama, Osamu Kawamura, Motoyasu Kusano, and Toshio Uraoka. "PS01.016: ESOPHAGEAL DYSMOTILITY CAUSED BY ESOPHAGEAL EOSINOPHILIA REGULATES PATIENTS’ SYMPTOMS AND TREATMENT REQUIREMENTS." Diseases of the Esophagus 31, Supplement_1 (2018): 54–55. http://dx.doi.org/10.1093/dote/doy089.ps01.016.

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Abstract Background Only a few studies –none from Asia– have been reported on high-resolution manometry (HRM) assessment of esophageal motor function in eosinophilic esophagitis (EoE). This study aimed to evaluate esophageal motility in Japanese patients with esophageal eosinophil infiltration and to clarify the association between esophageal dysmotility and symptoms, endoscopic findings, severity of eosinophilic infiltration, blood eosinophil count, and response to treatment. Methods Ninety-two patients underwent both esophageal manometry and endoscopic biopsy to determine eosinophil infiltra

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Shahzad, Ghulamullah, Duane Moise, Seth Lipka, Kaleem Rizvon, and Paul J. Mustacchia. "Eosinophilic Enterocolitis Diagnosed by Means of Upper Endoscopy and Colonoscopy with Random Biopsies Treated with Budenoside: A Case Report and Review of the Literature." ISRN Gastroenterology 2011 (January 17, 2011): 1–3. http://dx.doi.org/10.5402/2011/608901.

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Intense infiltration of gastrointestinal and colonic mucosa with eosinophils or acidophilic gastroenteritis (EG) is a relatively uncommon picture for a pathologist endoscopist especially outside the pediatric age group and is highly suggestive of an ongoing chronic inflammatory process. Existing literature projected a hypothetical association with allergy but the exact pathophysiology is still unknown. Association with malabsorption, protein losing enteropathy, and refractory ulcers with gastrointestinal bleeding makes the clinical presentation more complicated. We present a unique case of dia

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Sealock, R. J., J. R. Kramer, G. Verstovsek, et al. "The prevalence of oesophageal eosinophilia and eosinophilic oesophagitis: a prospective study in unselected patients presenting to endoscopy." Alimentary Pharmacology & Therapeutics 37, no. 8 (2013): 825–32. http://dx.doi.org/10.1111/apt.12268.

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Maslenkina, K. S., L. M. Mikhaleva, E. N. Motylev, et al. "Clinical and morphological diagnosis of eosinophilic esophagitis." CLINICAL AND EXPERIMENTAL MORPHOLOGY 12, no. 3 (2023): 5–18. http://dx.doi.org/10.31088/cem2023.12.3.5-18.

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Eosinophilic esophagitis (EoE) is an immune-mediated disease that presents with dysphagia and esophageal bolus obstruction and is characterized by predominant intraepithelial eosinophilic infiltration at histology. The aim of our literature review was to delineate clinical and morphological EoE features in terms of differential diagnosis with other esophageal diseases, i.e., gastroesophageal reflux disease (GERD), inflammatory bowel diseases (IBDs), autoimmune diseases, and rare esophageal disorders. Clinical features of dysphagia and esophageal bolus obstruction and endoscopic criteria (accor

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Al Yaarubi, Z., A. Foster, V. Avinashi, G. Lam, L. Soller, and E. Chan. "A198 EOSINOPHILIC ESOPHAGITIS WITH STRICTURE PRESENTING SHORTING AFTER INITIATION OF ORAL PEANUT IMMUNOTHERAPY." Journal of the Canadian Association of Gastroenterology 3, Supplement_1 (2020): 71–72. http://dx.doi.org/10.1093/jcag/gwz047.197.

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Abstract Background Oral immunotherapy (OIT) is increasingly practiced outside of research settings with reasonable success (Soller 2019). With OIT, a patient eats their food allergen daily, gradually increasing the dose, with the goal to prevent or reduce the severity of an anaphylactic reaction. One of the described adverse events of OIT is a risk of developing Eosinophilic Esophagitis (EoE), with cited frequency of 2.7% (Lucendo 2014). In addition, OIT is typically contraindicated in patients with known EoE but patients are not routinely screened for EoE prior to initiation of OIT. Aims To

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Holmes, Thomas, Chadi Makary, Aykut A. Unsal, Paul Biddinger, Camilo Reyes-Gelves, and Stilianos E. Kountakis. "How Does Age Impact Presentation and Outcomes in Chronic Rhinosinusitis?" Annals of Otology, Rhinology & Laryngology 129, no. 9 (2020): 872–77. http://dx.doi.org/10.1177/0003489420919124.

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Objectives/Hypothesis: The presence of eosinophilia and nasal polyps are well-established prognostic indicators of chronic rhinosinusitis (CRS). The importance of demographic background, such as age, as independent variables has not been elucidated while taking these factors into account. Study Design: Respective review. Methods: CRS patients who underwent primary surgical treatment were subdivided based on age (young adults = age 18-39, adults = age 40-64, and elderly = age 65+). Groups were then subdivided based on tissue eosinophilia and nasal polyposis. Sinonasal Outcome Test (SNOT-22), Lu

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LEITE, Carine, Luiz Edmundo MAZZOLENI, Diego de Mendonça UCHOA, Juliana Araújo CASTANHO, Felipe MAZZOLENI, and Guilherme Becker SANDER. "ASSOCIATION OF DUODENAL EOSINOPHILIC INFILTRATE WITH HELICOBACTER PYLORI INFECTION, BUT NOT WITH FUNCTIONAL DYSPEPSIA." Arquivos de Gastroenterologia 57, no. 1 (2020): 74–78. http://dx.doi.org/10.1590/s0004-2803.202000000-13.

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ABSTRACT BACKGROUND: The role of Helicobacter pylori infection on eosinophilic infiltration in duodenal mucosa is poorly studied. An increase in the number of eosinophils in duodenum has been associated with functional dyspepsia. OBJECTIVE: To evaluate the influence of H. pylori infection on duodenal eosinophil count and the role of eosinophilic infiltrate of duodenum in functional dyspepsia. METHODS: Positive and negative H. pylori individuals were included. Both functional dyspeptic patients according to Rome III criteria (cases) and individuals without gastrointestinal symptoms (controls) w

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Dellon, Evan S., Olga Speck, Kimberly Woodward, et al. "Distribution and variability of esophageal eosinophilia in patients undergoing upper endoscopy." Modern Pathology 28, no. 3 (2014): 383–90. http://dx.doi.org/10.1038/modpathol.2014.110.

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Brescia, Giuseppe, Daniela Parrino, Claudia Zanotti, et al. "Blood Eosinophil and Basophil Values Before and After Surgery for Eosinophilic-type Sinonasal Polyps." American Journal of Rhinology & Allergy 32, no. 3 (2018): 194–201. http://dx.doi.org/10.1177/1945892418768590.

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Background Blood eosinophil and basophil levels have recently been considered for the purpose of endotyping chronic rhinosinusitis with nasal polyps (CRSwNP). Histologically, eosinophilic-type CRSwNPs have been associated with high recurrence rates after treatment. Objective The present study was the first to compare blood eosinophil and basophil counts in eosinophilic-type CRSwNP patients before and after endoscopic sinus surgery. Methods The study concerned 79 consecutive patients with histologically confirmed eosinophilic-type CRSwNP treated with endoscopic sinus surgery. Results A signific

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Marasco, Giovanni, Pierfrancesco Visaggi, Mariagiulia Vassallo, et al. "Current and Novel Therapies for Eosinophilic Gastrointestinal Diseases." International Journal of Molecular Sciences 24, no. 20 (2023): 15165. http://dx.doi.org/10.3390/ijms242015165.

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Eosinophilic gastrointestinal diseases (EGIDs) are an emerging group of pathological entities characterized by an eosinophil-predominant infiltration of different tracts of the gut in the absence of secondary causes of eosinophilia. According to the specific tract of the gut involved, EGIDs can be classified into eosinophilic esophagitis (EoE), eosinophilic gastritis (EoG), eosinophilic enteritis (EoN), and eosinophilic colitis (EoC). The epidemiology of EGIDs is evolving rapidly. EoE, once considered a rare disease, now has an incidence and prevalence of 7.7 new cases per 100,000 inhabitants

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Barchi, Alberto, Edoardo Vespa, Sandro Passaretti, et al. "The Dual Lens of Endoscopy and Histology in the Diagnosis and Management of Eosinophilic Gastrointestinal Disorders—A Comprehensive Review." Diagnostics 14, no. 8 (2024): 858. http://dx.doi.org/10.3390/diagnostics14080858.

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Eosinophilic Gastrointestinal Disorders (EGIDs) are a group of conditions characterized by abnormal eosinophil accumulation in the gastrointestinal tract. Among these EGIDs, Eosinophilic Esophagitis (EoE) is the most well documented, while less is known about Eosinophilic Gastritis (EoG), Eosinophilic Enteritis (EoN), and Eosinophilic Colitis (EoC). The role of endoscopy in EGIDs is pivotal, with applications in diagnosis, disease monitoring, and therapeutic intervention. In EoE, the endoscopic reference score (EREFS) has been shown to be accurate in raising diagnostic suspicion and effective

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Dellon, Evan S., Olga Speck, Kimberly Woodward, et al. "Clinical and Endoscopic Characteristics do Not Reliably Differentiate PPI-Responsive Esophageal Eosinophilia and Eosinophilic Esophagitis in Patients Undergoing Upper Endoscopy: A Prospective Cohort Study." American Journal of Gastroenterology 108, no. 12 (2013): 1854–60. http://dx.doi.org/10.1038/ajg.2013.363.

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Sawada, Akinari, Atsushi Hashimoto, Risa Uemura, et al. "Association between endoscopic findings of eosinophilic esophagitis and responsiveness to proton pump inhibitors." Endoscopy International Open 07, no. 04 (2019): E433—E439. http://dx.doi.org/10.1055/a-0859-7276.

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Abstract Background and study aims Endoscopic findings of esophageal eosinophilia sometimes localize to small areas of the esophagus. A previous study suggested that pathogenesis of localized-type eosinophilic esophagitis (LEoE) was associated with acid reflux. However, LEoE treatment outcomes have not been studied. We aimed to analyze the clinical and histologic significance of LEoE in comparison with diffuse-type eosinophilic esophagitis (DEoE). Patients and methods This study included 106 patients with esophageal eosinophilia. Esophageal eosinophilia was defined as a condition where the max

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