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Journal articles on the topic 'Epidermoid Lewis lung carcinoma'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Kiseleva, M. P., V. S. Pokrovsky, L. M. Borisova, I. S. Golubeva, and L. V. Ektova. "N-glycosidesindolo[2,3,-a]pyrrolo[3,4,-c]carbazole derivatives chemical structure influence on antitumor activity." Russian Journal of Biotherapy 18, no. 2 (2019): 32–39. http://dx.doi.org/10.17650/1726-9784-2019-18-2-32-39.

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Introduction . The report considers the prospect of rational approach to the new anticancer agents creation based on indolocarbazole derivatives.Objective . To conduct a comparative study of 12 domestic N-glycosides, indolo[2,3-a]pirrolo[2,3-a]carbazole derivatives in the course of “structure – activity” bond analysis.Materials and methods . The investigation of influence of 12 carbohydrate – containing indolocarbazoles, synthesized in N. N. Blokhin Russian Cancer Research Center of the Ministry of Health of Russia, performed on models of solid transplantable mouse tumors: lung Lewis epidermoi

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2

G.G., Kudryashov,, Tochilnikov, G.V., Zmitrichenko, Yu.G., et al. "PECULIARITIES OF THE COURSE OF LEWIS LUNG EPIDERMOID CARCINOMA IN MICE INFECTED WITH MYCOBACTER TUBERCULOSIS." CARDIOMETRY, no. 24 (November 30, 2022): 23–24. http://dx.doi.org/10.18137/cardiometry.2022.24.conf.10.

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The potential relationship between pulmonary tuberculosis and lung cancer remains still poorly understood. The aim of our work was to study the features of the course of the tumor process and pulmonary tuberculosis in mice infected with Mycobacterium tuberculosis with transplanted Lewis epidermoid lung carcinoma.

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Dodokhova, Margarita A., Andrei V. Safronenko, Inga M. Kotieva, Margarita S. Alkhuseyn-Kulyaginova, Dmitry B. Shpakovsky, and Elena R. Milaeva. "Impact of organotin compounds on the growth of epidermoid Lewis carcinoma." Research Results in Pharmacology 7, no. (4) (2021): 81–88. https://doi.org/10.3897/rrpharmacology.7.71455.

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Introduction: Search for new compounds with a broad antitumor and antimetastatic potency due to multiple targeting remains important in medicinal chemistry, pharmacology and oncology. We report the efficacy of hybrid organotin agents bis-(3,5-di-tert-butyl-4-hydroxyphenylthiolate) dimethyltin (Ме3) and (3,5-di-tert-butyl-4-hydroxyphenylthiolate) triphenyltin (Ме5). Materials and methods: The compounds were administered to mice bearing the spontaneously metastatic epidermoid Lewis lung carcinoma (LLC). The efficacy of the treatment was evaluated by mean life span, percentage of tumor growth inh

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Dodokhova, M. A., M. A. Akimenko, O. V. Voronova, et al. "Comparative analysis of the use of B16 melanoma and epidermoid Lewis lung carcinoma models for preclinical studies of compounds with a putative antitumor effect." Ural Medical Journal 22, no. 5 (2023): 66–76. http://dx.doi.org/10.52420/2071-5943-2023-22-5-66-76.

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Introduction The search for new compounds with putative antitumor effects and the development of domestic anticancer and antimetastatic drugs based on them is a priority task for specialists in the field of medical chemistry, experimental pathophysiology and pharmacology. Melanoma B16 and Lewis lung epidermoid carcinoma are universal models for evaluating the effect of compounds with putative antitumor action on the primary focus of tumor growth and the process of tumor cells dissemination.The aim of the work is to determine the feasibility of using models of solid tumor growth and metastasis

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Kiseleva, M. P., I. S. Golubeva, V. P. Deryagina, et al. "Influence of Polysaccharide from Helianthus tuberosus L. on Antiproliferative Activity of N-Glycoside Indolo[2,3-a]carbazole Derivative LCS-1269." Biofizika 69, no. 5 (2024): 1109–17. http://dx.doi.org/10.31857/s0006302924050164.

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The Lewis model of epidermoid carcinoma that developed in the lungs of F1(C57Bl/6 × DBA/2) hybrid mice has been used while investigating antitumor activity of the N-glycoside derivative indolo[2,3-a]carbazole (LCS-1269) with a polysaccharide from Helianthus tuberosus L. as an adjuvant agent. The antitumor effect of LCS-1269 together with the polysaccharide was evaluated by the inhibition of tumor growth in treated ani mals in comparison to the control group. As a result, it was found that combination of LCS-1269 with the polysaccharide from Helianthus tuberosus L. provided more pronounced ther

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Dodokhova, Margarita A., Andrei V. Safronenko, Inga M. Kotieva, Margarita S. Alkhuseyn-Kulyaginova, Dmitry B. Shpakovsky, and Elena R. Milaeva. "Impact of organotin compounds on the growth of epidermoid Lewis carcinoma." Research Results in Pharmacology 7, no. 4 (2021): 81–88. http://dx.doi.org/10.3897/rrpharmacology.7.71455.

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Introduction: Search for new compounds with a broad antitumor and antimetastatic potency due to multiple targeting remains important in medicinal chemistry, pharmacology and oncology. We report the efficacy of hybrid organotin agents bis-(3,5-di-tert-butyl-4-hydroxyphenylthiolate) dimethyltin (Ме3) and (3,5-di-tert-butyl-4-hydroxyphenylthiolate) triphenyltin (Ме5). Materials and methods: The compounds were administered to mice bearing the spontaneously metastatic epidermoid Lewis lung carcinoma (LLC). The efficacy of the treatment was evaluated by mean life span, percentage of tumor growth inh

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7

Kudriashov, G. G., A. O. Nefedov, G. V. Tochilnikov, et al. "THE EFFECT OF TUBERCULOSIS ON THE COURSE OF LUNG CARCINOMA IN THE EXPERIMENT." Molekulyarnaya Meditsina (Molecular medicine) 21, no. 1 (2023): 43–49. http://dx.doi.org/10.29296/24999490-2023-01-06.

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Introduction. One of the problems of modern medicine is the low efficiency of treatment of patients with a coexistence of lung cancer and active tuberculosis. Optimal treatment regimens for coexistence pathology have not been developed at present. In recent years, fundamental research aimed to studying the unexplained mechanisms of the occurrence and course of coexistence pathology. The aim of the study was to investigate the peculiarities of the effect of tuberculosis with different drug resistance on the course of lung carcinoma in an experiment. Methods. The study was performed on 72 mice o

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Saprykina, N. S., L. M. Borisova, M. P. Kiseleva, et al. "Antitumor activity of ormustine against transplantable solid murine tumors. Part I." Russian Journal of Biotherapy 16, no. 4 (2017): 55–60. http://dx.doi.org/10.17650/1726-9784-2017-16-4-55-60.

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Background. Drugs of nitrosourea class are actively and successfully administered in oncology practice. However, at present, the search for new antitumor agents of this class is very urgent. Objective: to examine in vivo antitumor activity of ormustine, a new Russian drug from alkylnitrosourea class, against solid transplantable murine tumors: melanoma B16 and epidermoid Lewis lung carcinoma. Materials and methods. The assessment of antitumor activity of ormustine and a reference drug mustophoran (Les Labolatories Servier, France) was carried out in B6D2F1 mice. Ormustine was administered intr

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9

Kladnytska, Larysa, Viktor Tomchuk, Vladyslav Velychko, Volodymyr Salata, and Jakov Šengaut. "Influence of allogeneic mesenchymal stem cells of red bone marrow culture on the development of Lewis lung epidermoid carcinoma in vivo." Ukrainian journal of veterinary sciences 15, no. 2 (2024): 102–20. http://dx.doi.org/10.31548/veterinary2.2024.102.

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The relevance of this study is conditioned by the widespread use of stem cells in veterinary medicine, a wide range of studies and ambiguous data on the oncoprotective properties of stem cells of different origins. In this regard, the purpose of this study was to investigate the course of the tumour process in Lewis lung carcinoma and the specific features of the effect of allogeneic mesenchymal stem cells of red bone marrow culture on it. The leading approach to investigating this problem was the method of modelling Lewis lung carcinoma in C57BL6 mice and the use of stem cells. The use of all

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10

Kotieva, Inga Movlievna, Margarita Avdeevna Dodokhova, Andrey Vladimirovich Safronenko, et al. "Antitumor effectiveness of combination therapy with platinum and hybrid organotin compound on the Lewis epidermoid carcinoma model with metronomic administration." Journal of Clinical Oncology 40, no. 16_suppl (2022): e15080-e15080. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.e15080.

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e15080 Background: The prevalence of lung malignancies in Russia in 2019 was 100.5 per 100,000 population, which is 2.5% more than in the previous year. Drug therapy remains one of the main methods of treatment of malignant lung neoplasms. An urgent task for specialists in experimental pharmacology and oncology is searching for new antitumor compounds. Hybrid organotin compound (3,5-di-tert-butyl-4-hydroxyphenylthiolate)triphenylol) is a promising candidate for antitumor drugs [Milaeva E.R. et al. Novel selective anticancer agents based on Sn and Au complexes. Pure & Applied Chemistry. 202

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Жмурина, М. А., В. В. Врублевская, Ю. Ю. Скарга, В. С. Петренко, В. К. Жалимов та О. С. Моренков. "ИНТЕРНАЛИЗАЦИЯ КЛЕТКАМИ И ПРОТИВООПУХОЛЕВАЯ АКТИВНОСТЬ АНТИТЕЛ И ИММУНОТОКСИНОВ, СПЕЦИФИЧНЫХ К -ИЗОФОРМЕ БЕЛКА ТЕПЛОВОГО ШОКА 90". Биофизика 65, № 6 (2020): 1118–25. http://dx.doi.org/10.31857/s0006302920060113.

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We showed that the mouse monoclonal antibodies directed against the beta isoform of heat shock protein 90 (Hsp90beta) bind specifically to Hsp90beta found on the surface of tumor and untransformed cells. After binding to membrane-associated Hsp90beta, antibodies actively dissociated into the culture medium and were internalized by cells. An immunoconjugate prepared on the basis of the Hsp90beta-specific antibody and the cytotoxic agent mertansine did not exhibit high cytotoxic activity against tumor cells in vitro. The injection of the Hsp90beta-specific antibody into mice did not influence th

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Komarova, E. F., A. S. Morkovnik, O. N. Zhukovskaya, et al. "A benzimidazole derivative as an effective antitumor agent in terms of syngeneic lung tumors and melanoma treatment." South Russian Journal of Cancer 3, no. 1 (2022): 15–21. http://dx.doi.org/10.37748/2686-9039-2022-3-1-2.

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Purpose of the study. Evaluation of the effect of the benzimidazole derivative dihydrobromide‑2-(3,4‑dihydroxyphenyl)- 9‑diethylamino-ethylimidazo-[ 1,2‑a] benzimidazole (RU‑185) on the growth of Lewis lung epidermoid carcinoma and B16-F10 melanoma when administered intragastrically.Materials and methods. For the experiment, we used female C57Bl/6j mice, which were inoculated subcutaneously with syngeneic tumors: Lewis lung carcinoma (LLC) and B16-F10 melanoma. RU‑185 was administered intragastrically to animals in a volume of 0.3 ml for 10 days, 1 time per day. For both tumors, depending on s

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Dodokhova, Margarita Avdeevna, Inga Movlievna Kotieva, Andrej Vladimirovich Safronenko, et al. "Organotin compounds as effective antimetastatic substances in the treatment of epidermoid lung carcinoma Lewis (LLC) in an experiment." Journal of Clinical Oncology 39, no. 15_suppl (2021): e15054-e15054. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e15054.

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e15054 Background: Lung cancer occupies one of the first places in the structure of oncological diseases in the world. Reducing the life expectancy of patients, as a rule, occurs as a result of metastatic complications, so the search for new antimetastatic agents is an urgent task for experimental pharmacology and oncology. The aim of our study is to assess the severity of metastatic lesion in the Lewis lung epidermoid carcinoma (LLC) model in the presence of an organotin compound. Methods: The study was conducted on experimental C57BL/6 mice (n = 24, each group contained 12 mice) with LLC (su

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14

Pokrovsky, V. S., E. M. Treshalina, E. V. Lukasheva, and L. A. Sedakova. "DEVELOPMENT OF INTRAVENOUS ADMINISTRATION OF L-LYSINE-ALPHA-OXIDASE FROM TRICHODERMA CF. AUREOVIRIDE RIFAI BKMF-4268 REGIME CONTROLLED BY SAFETY AND EFFICACY OF TREATMENT." Russian Journal of Oncology 18, no. 2 (2013): 10–14. http://dx.doi.org/10.17816/onco39944.

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Various doses and modes of intravenous L-lysine-alpha-oxidase application on tumor models in mice under the control of efficacy and tolerability have been studied. Optimal choice scheme provides introduction of the first relatively high starting dose and subsequent maintenance doses comprising А or % of the first ("discrete" mode). The efficiency and an acceptable tolerability has been shown during "discrete" 5-fold treatment course with intravenous cumulative doses of 450-550 U/kg. By treating L-lysine-alpha-oxidase in the "discrete" mode following tumor-bearing mice have been sensitive: brea

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15

Kiseleva, Marina P., Z. S. Smirnova, L. M. Borisova, et al. "Search for new antitumor compounds among n-glycoside indolo[2,3-a]carbazole derivatives." Russian Journal of Oncology 20, no. 1 (2015): 33–37. http://dx.doi.org/10.17816/onco40133.

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The study investigated antitumor activity of 10 new compounds in the series of N-glycosides of indolo[2,3-a] carbazoles. The results identified strong antitumor activity of compounds LCS-1208, LCS -1054, LCS -999 and LCS-1006 against lymphocytic leukemia P-388 (ILS=85 - 119%). Glycosides LCS-1208, LCS-999 and LCS-1006 exhibited high antitumor activity immediately after treatment for Lewis epidermoid lung carcinoma LLC (TGI =90%). In addition, the antitumor effect after LCS-999 and LCS-1006 treatment kept on for 10 days, and LCS-1208 - for 15 days. Glycoside LCS-1208 had a therapeutic efficienc

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Antipova, Yu E., K. T. Erimbetov та O. V. Buyuklinskaya. "Development of a Clathrate Complex of 3-(2-Phenylethyl)-2-Thioxo-1,3-Thiazolidin-4-one with β-Cyclodextrin and Studying its Antitumor Activity". Journal Biomed 20, № 3E (2024): 14–19. http://dx.doi.org/10.33647/2713-0428-20-3e-14-19.

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This work is aimed at developing and studying the antitumor action of a clathrate complex of a rhodanine derivative (RD) of the 3-(2-phenylethyl)-2-thioxo-1,3-thiazolidin-4-one compound with β-cyclodextrin. In terms of physicochemical and biopharmaceutical properties, the RD clathrate complex with β-cyclodextrin with a mass ratio of 1:5 and an average particle size of 40.5 nm is a promising pharmacologically active drug. The developed RD clathrate complex with β-cyclodextrin exhibits a pronounced antiproliferative and antimetastatic effect against epidermoid Lewis lung carcinoma tumors. RD as

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Karatsuba, T., G. Shayakhmetova, O. Khavych, and O. Puskov. "P08-09 Adrenalin hydrotartrate promotes metastasis and levels the anti-metastatic effect of Chlofiden in the Lewis epidermoid lung carcinoma model." Toxicology Letters 368 (September 2022): S144. http://dx.doi.org/10.1016/j.toxlet.2022.07.408.

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18

Kudriashov, Grigorii G., Andrey O. Nefedov, Grigorii V. Tochilnikov, et al. "Original experimental model of tuberculosis and lung cancer." Pediatrician (St. Petersburg) 13, no. 5 (2022): 33–42. http://dx.doi.org/10.17816/ped13533-42.

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BACKGROUND: The potential relationship between pulmonary tuberculosis and lung cancer has been the subject of intense interest over the past few decades. Nevertheless, the features of the pathogenesis of concomitant pathology remain poorly studied. AIM: The ain of the study to develop an experimental model of the concomitant pathology of tuberculosis and lung cancer. MATERIALS AND METHODS: The study was performed on mice of the C57BL/6 line at the age of two months in four groups: 1st intact mice (n = 12), 2nd mice without a tumor infected with tuberculosis (n = 24), 3rd tumor-bear

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19

Meerovich, G. A., L. M. Borisova, A. P. Bud’Ko, et al. "Study of level and selectivity of liposomal form of photosensitiser hydroxyaluminium tetra-3-phenylthiophthalocyanine accumulation on transplantable mice tumor models at different ways of transplantation." Russian Journal of Biotherapy 16, no. 4 (2017): 74–79. http://dx.doi.org/10.17650/1726-9784-2017-16-4-74-79.

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Background. Current work is devoted to the study in vivo of concentration and selectivity of accumulation of infrared photosensitizer (PS) hydroxyaluminium tetra-3-phenylthiophthalocyanine in liposomal form in intramuscularly and subcutaneously transplanted mice tumor models in comparison to normal tissues. Objective: to study the level and selectivity of accumulation of hydroxyaluminium tetra-3-phenylthiophthalocyanine liposomal form on mice tumor models in order to optimize the transplantation approach and the starting of photodynamic treatment. Materials and methods. A range of transplantab

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20

Филимонова, М. В., В. В. Южаков, А. С. Филимонов, et al. "COMPARATIVE STUDY OF THE EFFECTS OF NOS INHIBITOR T1023 AND BEVACIZUMABUM ON GROWTH AND MORPHOLOGY OF LEWIS LUNG CARCINOMA." ZHurnal «Patologicheskaia fiziologiia i eksperimental`naia terapiia», no. 2() (May 27, 2019): 89–98. http://dx.doi.org/10.25557/0031-2991.2019.02.89-98.

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Цель исследования - изучение механизмов противоопухолевой активности ингибитора NOS Т1023 и оценка перспективности его дальнейшей разработки. Методика. В качестве опухолевой модели использована эпидермоидная КЛЛ, штамм которой получен из банка опухолевых материалов ФГБУ РОНЦ им. Н.Н. Блохина и поддерживался на самцах мышей C57BL6j. КЛЛ трансплантировали самцам мышей F1 (CBA´C57BL6j) путем подкожного введения 1,5×106 клеток карциномы в 0,1 мл суспензии на основе среды 199 в область латеральной поверхности правого бедра. Для сравнительной оценки противоопухолевой эффективности использовали ингиб

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Kovalenko, L. P., K. V. Korzhova, S. V. Nikitin, E. A. Ivanova, and R. V. Zhurikov. "Correction of serum prooncogenic cytokines and metastases by 5-hydroxypyrimidine derivatives and doxorubicin after removal of a primary tumor node in mice with the Lewis lung epidermoid carcinoma." Biomeditsinskaya Khimiya 69, no. 1 (2023): 39–45. http://dx.doi.org/10.18097/pbmc20236901039.

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The effect of a single injection of doxorubicin, 8-day administration of two 5-hydroxypyrimidine derivatives, SNK-411 (2-Isobutyl-4,6-dimethyl-5-hydroxypyrimidine) and SNK-578 (hydrochloride of 2-isobutyl-4,6-dimethyl-5-hydroxypyrimidine), on metastases, lifespan and serum cytokines has been investigated in С57ВL/6 mice after removal of a primary tumor node of Lewis lung carcinoma (LLC). LLC cells (1×106) were injected in the footpad of right hind feet of mice in control and experimental groups; after 14 days of tumor development the hind feet with the tumor were amputated at the ankle level.

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Филимонова, М. В., В. М. Макарчук, Л. И. Шевченко та А. С. Филимонов. "Effect of a nos inhibitor, t1023, in combination with γ-irradiation and cyclophosphamide on growth and metastasis of Lewis lung carcinoma". ZHurnal «Patologicheskaia fiziologiia i eksperimental`naia terapiia», № 3() (27 червня 2019): 105–9. http://dx.doi.org/10.25557/0031-2991.2019.03.105-109.

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Цель работы - изучение антинеопластических эффектов при комбинированном воздействии ингибитора NOS Т1023 с γ-излучением и циклофосфамидом. Методика. В работе использован штамм эпидермоидной карциномы легких Льюиса. Выполнено 2 независимых эксперимента: в одном изучали антинеопластические эффекты при раздельном и комбинированном воздействии Т1023 и γ-излучения, в другом - при раздельном и комбинированном воздействии Т1023 и циклофосфамида. Особям 1-й опытной группы в обоих экспериментах с 7-х по 20-е сут роста карциномы ежедневно вводили соединение Т1023 в дозе 60 мг/кг внутрибрюшинно. В первом

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Lozac'h, P., P. Topart, J. Etienne, and J. F. Charles. "Ivor Lewis operation for epidermoid carcinoma of the esophagus." Annals of Thoracic Surgery 52, no. 5 (1991): 1154–57. http://dx.doi.org/10.1016/0003-4975(91)91300-k.

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Aktas, Seref, Halim Demiral, Selcuk Bilgi, Tuncay Caglar, and Osman U. Calpur. "Patellar metastasis from a lung epidermoid carcinoma." Yonsei Medical Journal 39, no. 5 (1998): 474. http://dx.doi.org/10.3349/ymj.1998.39.5.474.

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Teunissen, G. H. B., A. A. Stokhof, W. Th C. Wolvekamp, S. A. Goedegebuure, and Th S. G. A. M. Ingh. "Lung Infarction and Epidermoid Carcinoma in a Dog." Zentralblatt für Veterinärmedizin Reihe A 28, no. 1 (2010): 47–52. http://dx.doi.org/10.1111/j.1439-0442.1981.tb01161.x.

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Gregory, Jules, Souhail Bennani, Gaël Freche, Audrey Mansuet-Lupo, Marie-Pierre Revel, and Guillaume Chassagnon. "Synchronous Presentation of Pheochromocytoma and Epidermoid Lung Carcinoma." Annals of Thoracic Surgery 106, no. 2 (2018): e99. http://dx.doi.org/10.1016/j.athoracsur.2018.02.032.

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Dómine, M., L. Estévez, A. Fernández Aramburo, et al. "Combined treatment for advanced epidermoid carcinoma of lung." European Journal of Cancer 29 (January 1993): S165. http://dx.doi.org/10.1016/0959-8049(93)91535-s.

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28

Ukei, S., I. Saiki, and I. Azuma. "Monoclonal antibodies to Lewis lung carcinoma." Journal of Cancer Research and Clinical Oncology 110, no. 2 (1985): 103–9. http://dx.doi.org/10.1007/bf00402720.

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Maeda, Y., T. Hirai, H. Yamato, et al. "Animal Pharmacological Effects of 24R,25-Dihydroxyvitamin D3 One of the Endogenous Substances Regulating Calcium Metabolism." Journal of International Medical Research 16, no. 2 (1988): 125–33. http://dx.doi.org/10.1177/030006058801600207.

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Lewis lung carcinoma was found to cause hypercalcaemia in tumour-bearing mice. 24 R,25-Dihydroxyvitamin D3, a naturally occurring steric epimer, significantly prolonged the survival time of mice with Lewis lung carcinoma. It also had an analgesic effect in mice with Lewis lung carcinoma and increased the strength of bone weakened by the carcinoma which causes abnormal calcium metabolism and results in hypercalcaemia.

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Stepanov, Yu V., Yu R. Yakshibaeva, D. L. Kolesnik, and G. I. Solyanik. "2-DEOXYGLUCOSE PROMOTES ANTI-INFLAMMATORY POLARIZATION OF PERITONEAL MACROPHAGES IN MICE WITH LEWIS LUNG CARCINOMA." Oncology 25, no. 1 (2024): 44–48. http://dx.doi.org/10.15407/oncology.2024.01.044.

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Summary. Aim: to investigate the effect of 2-deoxyglucose at a wide range of concentrations on the polarization of peritoneal macrophages of intact mice and mice with Lewis lung carcinoma. Object and methods: peritoneal macrophages obtained from intact female C57BL/6 mice and Lewis lung carcinoma-bearing mice. isolation of peritoneal macrophages, determination of nitric oxide production and arginase activity. Results: 2-deoxyglucose does not affect nitric oxide production and arginase activity of peritoneal macrophages of intact mice. 2-deoxyglucose at a concentration of 10 mM significantly (b

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Gangemi, Vincenzo, Patrizia Volpino, Nadia D'Andrea, et al. "Lung Cancer Surgery in Elderly Patients." Tumori Journal 82, no. 3 (1996): 237–41. https://doi.org/10.1177/030089169608200311.

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Aims and Background Bronchogenic carcinoma is the major cancer-related cause of death in patients aged 70 years and over, and its incidence is rising. The aim of our study was to compare the incidence and the prognostic effect of the parameters characterizing resected patients with non-small-cell lung cancer (NSCLC) when stratified by age. Of 283 NSCLC patients candidates to a long-term follow-up program and who underwent pulmonary resection in our Unit, 34 (12%) were older than 70 years. Methods All patients had been preoperatively selected to exclude those with severe or multiple organ syste

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Garcia-Sanz, Manuel, Rafael Simón-Marín, and Enrique Hilario. "Morphological Characterization of Lewis Lung Carcinoma (3LL). A Light and Electron Microscopic Study." Tumori Journal 75, no. 1 (1989): 23–27. http://dx.doi.org/10.1177/030089168907500107.

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Primary tumor and its metastases of subcutaneously injected Lewis lung carcinoma (3LL) of the mouse were examined by light and electron microscopy. Although the optical appearance, in both cases, was of a indiffentiated carcinoma, the ultrastructural observation showed characteristic intracyto-plasmic myelinoid bodies similar to those seen in type II pneumocytes in normal lung. These findings suggest that Lewis lung carcinoma is a carcinoma derived from granular pneumocytes equivalent to human alveolar cell carcinoma. The histological and embryological aspects ot type II pneumocytes that could

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33

Lozac'h, Patrick, Philippe Topart, and Michel Perramant. "Ivor Lewis procedure for epidermoid carcinoma of the esophagus. A series of 264 patients." Seminars in Surgical Oncology 13, no. 4 (1997): 238–44. http://dx.doi.org/10.1002/(sici)1098-2388(199707/08)13:4<238::aid-ssu4>3.0.co;2-6.

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Sin, Thomas K., James Z. Zhu, Guohua Zhang, and Yi-Ping Li. "p300 Mediates Muscle Wasting in Lewis Lung Carcinoma." Cancer Research 79, no. 7 (2019): 1331–42. http://dx.doi.org/10.1158/0008-5472.can-18-1653.

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35

Sato, Toshio, Kimihiko Takusagawa, Noboru Asoo, Nobuko Kumano, Miki Hasuike, and Kiyoshi Konno. "Conversion of Lewis Lung Carcinoma into Ascitic Form." Oncology 46, no. 3 (1989): 188–92. http://dx.doi.org/10.1159/000226712.

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36

Maharajan, Veeramani, Pratibha Maharajan, Pasquale Martinelli, Giuseppe Paino, and Gaetano V. Pelagalli. "Transplantation of Lewis Lung Carcinoma in Mouse Uterus." Pathobiology 58, no. 5 (1990): 287–91. http://dx.doi.org/10.1159/000163598.

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Marino, Andrew A., Don Morris, and Thomas Arnold. "Electrical treatment of Lewis lung carcinoma in mice." Journal of Surgical Research 41, no. 2 (1986): 198–201. http://dx.doi.org/10.1016/0022-4804(86)90025-9.

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38

Türken, Orhan, Durmus Etiz, Bülent Orhan, et al. "Muscle Metastasis as Initial Manifestation of Epidermoid Carcinoma of the Lung." Clinical Oncology 14, no. 2 (2002): 129–31. http://dx.doi.org/10.1053/clon.2001.0019.

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39

Pražák, J., O. Měřička, and J. Chytrý. "Histocompatibility locus antigens (HLA) in the epidermoid type of lung carcinoma." Journal of Cancer Research and Clinical Oncology 116, no. 5 (1990): 525–27. http://dx.doi.org/10.1007/bf01613006.

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Hayakawa, Kazushige, Norio Mitsuhashi, Nobuaki Nakajima, et al. "Radiation therapy for Stage I–III epidermoid carcinoma of the lung." Lung Cancer 8, no. 3-4 (1992): 213–23. http://dx.doi.org/10.1016/0169-5002(92)90009-9.

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41

Ohizumi, Yukio, Hiroshi Maezawa, and Tomoyuki Mori. "Effect of Local Hyperthermia on Lung Metastasis in Lewis Lung Carcinoma." Thermal Medicine(Japanese Journal of Hyperthermic Oncology) 4, no. 3 (1988): 199–205. http://dx.doi.org/10.3191/thermalmedicine.4.199.

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42

Alhusein-Kulyaginova, M. S., M. A. Dodokhova, S. Z. Agarizaeva, et al. "Evaluation of markers of apoptotic processes and peroxide oxidation of lipids of the mitochondrial fraction of the liver of animals carrying Lewis epidermoid carcinoma at different stages of the development of the tumor process with the introduction of organotin compounds with a tread fragment." South Russian Journal of Therapeutic Practice 4, no. 4 (2023): 89–94. http://dx.doi.org/10.21886/2712-8156-2023-4-4-89-94.

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Objective: to evaluate changes in markers of apoptotic processes and lipid peroxidation (POL) by accumulation of malondialdehyde (MDA) in the mitochondrial fraction of the liver of animals carrying Lewis epidermoid carcinoma at different stages of the tumor process with the introduction of bis-(3,5-di-tert-butyl-4-hydroxyphenyl)dimethylolol thiolate (Me-3) and (3,5-di-tert-butyl-4-hydroxyphenyl)triphenylololate (Me-5). Materials and methods: the work was performed using laboratory animals - female mice of the C57Bl line/6. 48 hours after the Lewis epidermoid carcinoma strain was transplanted,

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Yan, Dejun, Michael E. Geusz, and Roudabeh J. Jamasbi. "Properties of Lewis Lung Carcinoma Cells Surviving Curcumin Toxicity." Journal of Cancer 3 (2012): 32–41. http://dx.doi.org/10.7150/jca.3659.

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Kristensen, P., C. Pyke, L. R. Lund, P. A. Andreasen, and K. Dan�. "Plasminogen activator inhibitor-type 1 in Lewis lung carcinoma." Histochemistry 93, no. 6 (1990): 559–66. http://dx.doi.org/10.1007/bf00272198.

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Pancar Yüksel, Esra, Burçin Çelik, Gökhan Şahin, et al. "Diagnosis of epidermoid lung carcinoma in a patient presenting with skin lesions." Journal of Experimental and Clinical Medicine 30, no. 3 (2013): 251–53. http://dx.doi.org/10.5835/jecm.omu.30.03.009.

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Islam, S. M. A., Muhammad Rafiqul Islam, and ATM Kamral Hasan. "P12-7 A young woman with muco-epidermoid carcinoma of the lung." Annals of Oncology 32 (July 2021): S335. http://dx.doi.org/10.1016/j.annonc.2021.05.692.

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Mattern, J., M. Bak, KH Hoever, and M. Volm. "Development of drug resistance in a human epidermoid lung carcinoma xenograft line." British Journal of Cancer 58, no. 1 (1988): 30–33. http://dx.doi.org/10.1038/bjc.1988.155.

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Ohizumi, Yukio, Satoshi Imamiya, Hiroshi Maezawa, Yoshifumi Tamai, Noboru Fukuhara, and Tomoyuki Mori. "Re-evaluation on lung metastases by local hyperthermia in Lewis lung carcinoma." Thermal Medicine(Japanese Journal of Hyperthermic Oncology) 7, no. 1 (1991): 23–32. http://dx.doi.org/10.3191/thermalmedicine.7.23.

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Cao, Y., C. Chen, J. A. Weatherbee, M. Tsang, and J. Folkman. "gro-beta, a -C-X-C- chemokine, is an angiogenesis inhibitor that suppresses the growth of Lewis lung carcinoma in mice." Journal of Experimental Medicine 182, no. 6 (1995): 2069–77. http://dx.doi.org/10.1084/jem.182.6.2069.

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We have found that two chemokines, recombinant gro-alpha and gro-beta, specifically inhibit growth factor-stimulated proliferation of capillary endothelial cells in a dose-dependent manner, whereas gro-gamma has no inhibitory effect. In vivo, gro-beta inhibits blood vessel formation in the chicken chorioallantoic membrane assay. It is sufficiently potent to effectively suppress basic fibroblast growth factor-induced corneal neovascularization after systemic administration in mice. Further, gro-beta significantly inhibits the growth of murine Lewis lung carcinoma in syngeneic C57B16/J and immun

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_, _. "Non–Small Cell Lung Cancer." Journal of the National Comprehensive Cancer Network 6, no. 3 (2008): 228. http://dx.doi.org/10.6004/jnccn.2008.0021.

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Lung cancer is the leading cause of cancer-related death in both men and women in the United States. An estimated 213,380 new cases (114,760 men and 98,620 women) of lung and bronchus cancer will be diagnosed in 2007, and 160,390 deaths (89,510 in men, 70,880 in women) are estimated to occur because of the disease. Non-small cell lung cancer (NSCLC) accounts for 80% to 85% of all lung cancer cases and includes 3 major types: (1) adenocarcinoma; (2) squamous cell (epidermoid) carcinoma; and (3) large-cell carcinoma. Adenocarcinoma is the most common type of lung cancer seen in the United States

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