Relevant bibliographies by topics / Epigenomics and epigenetics

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Epigenomics and epigenetics'

Author: Grafiati
Published: 10 December 2022
Last updated: 31 July 2025

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Journal articles on the topic "Epigenomics and epigenetics"

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Song, Pengtao, and Biaoru Li. "New Generation of Clinical Epigenetics Analysis and Diagnosis for Precision Medicine." Diagnostics 15, no. 12 (2025): 1539. https://doi.org/10.3390/diagnostics15121539.

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Following the application of epigenetic and epigenomics research into tumor diseases, cardiovascular disease, diabetes, hereditary diseases, and rare diseases, in vitro diagnostics (IVD) epigenetic and epigenomics are increasingly employed for those patients. Here, we review a clinical sampling of epigenetics and epigenomics from patients. We then present procedures, including the detection procedure of clinical epigenetic approaches from clinical samples, clinical epigenomic methods applied to those samples, the small cell number of epigenetics, and epigenomics. Finally, we present the curren
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Bunnik, Eline M., Marjolein Timmers, and Ineke LLE Bolt. "Ethical Issues in Research and Development of Epigenome-wide Technologies." Epigenetics Insights 13 (January 2020): 251686572091325. http://dx.doi.org/10.1177/2516865720913253.

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To date, few scholarly discussions on ethical implications of epigenetics and epigenomics technologies have focused on the current phase of research and development, in which researchers are confronted with real and practical ethical dilemmas. In this article, a responsible research and innovation approach, using interviews and an expert meeting, is applied to a case of epigenomic test development for cervical cancer screening. This article provides an overview of ethical issues presently facing epigenomics researchers and test developers, and discusses 3 sets of issues in depth: (1) informed
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Leite, Michel Lopes, and Fabricio F. Costa. "Epigenomics, epigenetics, and cancer*." Revista Pan-Amazônica de Saúde 8, no. 4 (2017): 23–25. http://dx.doi.org/10.5123/s2176-62232017000400006.

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Jirtle, Randy L. "The science of hope: an interview with Randy Jirtle." Epigenomics 14, no. 6 (2022): 299–302. http://dx.doi.org/10.2217/epi-2022-0048.

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In this interview, Professor Randy L Jirtle speaks with Storm Johnson, Commissioning Editor for Epigenomics, on his work on genomic imprinting, environmental epigenomics and the fetal origins of disease susceptibility. Professor Randy Jirtle joined the Duke University Department of Radiology in 1977 and headed the Epigenetics and Imprinting Laboratory until 2012. He is now Professor of Epigenetics in the Department of Biological Sciences at North Carolina State University, Raleigh, NC, USA. Jirtle's research interests are in epigenetics, genomic imprinting and the fetal origins of disease susc
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Majumder, Sanjoy, Rutupurna Das, Annapurna Sahoo, Kunja Bihari Satapathy, and Gagan Kumar Panigrahi. "Epigenetics, Epigenomics, and Personalized Medicine." Gene Expression 000, no. 000 (2024): 000. http://dx.doi.org/10.14218/ge.2024.00058.

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Peedicayil, J. "Beyond Genomics: Epigenetics and Epigenomics." Clinical Pharmacology & Therapeutics 84, no. 1 (2008): 25–26. http://dx.doi.org/10.1038/clpt.2008.26.

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Kim, Kyoung-Tae, Young-Seok Lee, and Inbo Han. "The Role of Epigenomics in Osteoporosis and Osteoporotic Vertebral Fracture." International Journal of Molecular Sciences 21, no. 24 (2020): 9455. http://dx.doi.org/10.3390/ijms21249455.

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Osteoporosis is a complex multifactorial condition of the musculoskeletal system. Osteoporosis and osteoporotic vertebral fracture (OVF) are associated with high medical costs and can lead to poor quality of life. Genetic factors are important in determining bone mass and structure, as well as any predisposition for bone degradation and OVF. However, genetic factors are not enough to explain osteoporosis development and OVF occurrence. Epigenetics describes a mechanism for controlling gene expression and cellular processes without altering DNA sequences. The main mechanisms in epigenetics are
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Mladenov, Velimir, Vasileios Fotopoulos, Eirini Kaiserli, et al. "Deciphering the Epigenetic Alphabet Involved in Transgenerational Stress Memory in Crops." International Journal of Molecular Sciences 22, no. 13 (2021): 7118. http://dx.doi.org/10.3390/ijms22137118.

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Although epigenetic modifications have been intensely investigated over the last decade due to their role in crop adaptation to rapid climate change, it is unclear which epigenetic changes are heritable and therefore transmitted to their progeny. The identification of epigenetic marks that are transmitted to the next generations is of primary importance for their use in breeding and for the development of new cultivars with a broad-spectrum of tolerance/resistance to abiotic and biotic stresses. In this review, we discuss general aspects of plant responses to environmental stresses and provide
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Dar, Fayaz Ahmad, Naveed Ul Mushtaq, Seerat Saleem, Reiaz Ul Rehman, Tanvir Ul Hassan Dar, and Khalid Rehman Hakeem. "Role of Epigenetics in Modulating Phenotypic Plasticity against Abiotic Stresses in Plants." International Journal of Genomics 2022 (June 14, 2022): 1–13. http://dx.doi.org/10.1155/2022/1092894.

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Plants being sessile are always exposed to various environmental stresses, and to overcome these stresses, modifications at the epigenetic level can prove vital for their long-term survival. Epigenomics refers to the large-scale study of epigenetic marks on the genome, which include covalent modifications of histone tails (acetylation, methylation, phosphorylation, ubiquitination, and the small RNA machinery). Studies based on epigenetics have evolved over the years especially in understanding the mechanisms at transcriptional and posttranscriptional levels in plants against various environmen
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Chen, Xiangsong, and Dao-Xiu Zhou. "Rice epigenomics and epigenetics: challenges and opportunities." Current Opinion in Plant Biology 16, no. 2 (2013): 164–69. http://dx.doi.org/10.1016/j.pbi.2013.03.004.

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Dissertations / Theses on the topic "Epigenomics and epigenetics"

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Baker, Katie. "The chromatin landscape of barley : gene expression, evolution and epigenetics." Thesis, University of Dundee, 2015. https://discovery.dundee.ac.uk/en/studentTheses/13a096cd-f45b-4e34-babd-ccb3ff3607ca.

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Barley (Hordeum vulgare) is an economically important crop species with a large diploid genome. Around a half of the barley genome and a fifth of the genes are constrained within a low-recombining pericentromeric (LR-PC) region. I explored the LR-PC gene component with a genomic investigation of gene expression, diversity and evolution. Chromatin environments were also explored in the LR and high recombining (HR) regions by surveying the genic and genomic distributions of nine histone modifications. Firstly, regions of HR and LR were identified and compared for gene evolution, expression and d
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Drong, Alexander Werner. "Comprehensive assessment of the role of DNA methylation in obesity and type 2 diabetes." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:c2df87d9-9929-4eb1-8c44-61452b88ea3c.

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Obesity and type 2 diabetes (T2D) are major risk factors for cardiovascular and other diseases and are currently undergoing an increase in global prevalence. The work presented in my thesis addresses the role epigenetics, specifically DNA methylation, plays in the susceptibility to obesity and T2D and deals with methodological issues in the analysis of DNA methylation data. I first combined epigenome-wide DNA methylation data across 38 adipose tissue samples with corresponding SNP and mRNA data for the same subjects. At 5% false discovery rate (FDR), methylation of 149 regions associate
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Franceschini, Gian Marco. "The DNA methylation landscape of metastatic prostate cancer: from characterization to liquid biopsy applications." Doctoral thesis, Università degli studi di Trento, 2023. https://hdl.handle.net/11572/364210.

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Epigenetic alterations are observed in virtually all cancer types, yet there is limited understanding of their role in tumorigenesis and evolution. The role of DNA methylation has been particularly elusive in this context. While this epigenetic mark has been extensively profiled in healthy and cancerous samples, our ability to understand its relationship with underlying biological processes is still limited. Moreover, recent advancements in the profiling of cell-free DNA in circulation have sparked renowned attention toward tissue-specific and cancer-specific DNA methylation patterns. In this
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Nordor, Akpéli. "Toward the identification of cancer/placenta epigenetic switches." Thesis, Sorbonne Paris Cité, 2016. http://www.theses.fr/2016USPCB097.

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Les cellules placentaires portent un génome différent du génome maternel, puisque 50% de leurs gènes proviennent du génome paternel. Cependant, comme les cellules cancéreuses après la transformation néoplasique, elles réussissent à envahir les tissus de leur hôte, échapper à son système immunitaire et induire une angiogenèse afin d’établir la grossesse. Les cellules cancéreuses et placentaires arborent aussi une différence majeure : alors que de tels mécanismes typiques des cancers sont incontrôlés dans les cellules cancéreuses, ils sont spatialement et temporairement contrôlés dans les cell
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Hernando, Herráez Irene 1985. "Evolutionary insights into human DNA methylation." Doctoral thesis, Universitat Pompeu Fabra, 2015. http://hdl.handle.net/10803/392140.

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DNA methylation is a crucial epigenetic modification involved in numerous biological processes. However, despite its functional importance, the evolutionary history of this modification and the mechanisms diving such changes are poorly understood. The aim of this thesis is to provide a better understanding of DNA methylation in the context of human recent evolution. We identified and described hundreds of regions presenting a human-specific DNA methylation pattern compared to great apes. We also analyzed for the first time the relationship between DNA methylation changes and sequence evolution
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Yen, Angela. "Computational epigenomics : gene regulation, comparative methodologies, and epigenetic patterns." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/105953.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2016.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Cataloged from student-submitted PDF version of thesis.<br>Includes bibliographical references (pages 203-225).<br>One of the fundamental aims of biology is to determine what lies at the root of differences across individuals, species, diseases, and cell types. Furthermore, the sequencing of genomes has revolutionized the way
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Severson, Paul Leamon. "Epigenomic Actions of Environmental Arsenicals." Diss., The University of Arizona, 2013. http://hdl.handle.net/10150/299122.

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Epigenetic dysfunction is a known contributor in carcinogenesis, and is emerging as a mechanism involved in toxicant-induced malignant transformation for environmental carcinogens such as arsenicals. In addition to aberrant DNA methylation of single genes, another manifestation of epigenetic dysfunction in cancer is agglomerative DNA methylation, which can participate in long-range epigenetic silencing that targets many neighboring genes and has been shown to occur in several types of clinical cancers. Using in vitro model systems of toxicant-induced malignant transformation, we found hundre
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Bhasin, Jeffrey M. "Methylome Sequencing Reveals the Context-Specific Functions of DNA Methylation in Indolent Versus Aggressive Prostate Cancer." Case Western Reserve University School of Graduate Studies / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=case148120498969955.

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Wang, Jianrong. "Computational algorithm development for epigenomic analysis." Diss., Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/48984.

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Multiple computational algorithms were developed for analyzing ChIP-seq datasets of histone modifications. For basic ChIP-seq data processing, the problems of ambiguous short sequence read mapping and broad peak calling of diffuse ChIP-seq signals were solved by novel statistical methods. Their performance was systematically evaluated compared with existing approaches. The potential utility of finding meaningful biological information was demonstrated by the applications on real datasets. For biological question driven data mining, several important topics were selected for algorithm developme
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Zhu, Yan. "Microfluidic Technology for Low-Input Epigenomic Analysis." Diss., Virginia Tech, 2018. http://hdl.handle.net/10919/83402.

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Epigenetic modifications, such as DNA methylation and histone modifications, play important roles in gene expression and regulation, and are highly involved in cellular processes such as stem cell pluripotency/differentiation and tumorigenesis. Chromatin immunoprecipitation (ChIP) is the technique of choice for examining in vivo DNA-protein interactions and has been a great tool for studying epigenetic mechanisms. However, conventional ChIP assays require millions of cells for tests and are not practical for examination of samples from lab animals and patients. Automated microfluidic chips off
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Books on the topic "Epigenomics and epigenetics"

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Spillane, Charles, and Peter McKeown, eds. Plant Epigenetics and Epigenomics. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0179-2.

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Spillane, Charles, and Peter C. McKeown, eds. Plant Epigenetics and Epigenomics. Humana Press, 2014. http://dx.doi.org/10.1007/978-1-62703-773-0.

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Craig, Jeffrey, and Nicholas C. Wong. Epigenetics: A reference manual. Caister Academic Press, 2011.

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Jirtle, Randy L. Environmental Epigenomics in Health and Disease: Epigenetics and Disease Origins. Springer Berlin Heidelberg, 2013.

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1941-, Hall Brian Keith, ed. Epigenetics: Linking genotype and phenotype in development and evolution. University of California Press, 2010.

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A, Russo V. E., Martienssen Robert A, and Riggs Arthur D, eds. Epigenetic mechanisms of gene regulation. Cold Spring Harbor Laboratory Press, 1996.

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Payne, Christopher J., ed. Epigenetics and Epigenomics. InTech, 2014. http://dx.doi.org/10.5772/57037.

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Epigenetics and Epigenomics. IntechOpen, 2014.

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Armstrong, Lyle. Epigenetics. CRC Press LLC, 2020.

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Armstrong, Lyle. Epigenetics. CRC Press LLC, 2020.

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Book chapters on the topic "Epigenomics and epigenetics"

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Skinner, Michael K. "Environmental Epigenetics and Epigenetic Transgenerational Inheritance." In Environmental Epigenomics in Health and Disease. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-23380-7_11.

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Tian, Xiuchun cindy. "Bovine Epigenetics and Epigenomics." In Bovine Genomics. Wiley-Blackwell, 2012. http://dx.doi.org/10.1002/9781118301739.ch11.

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Qiu, Chuan, Fangtang Yu, Hong-Wen Deng, and Hui Shen. "Clinical Epigenetics and Epigenomics." In Translational Bioinformatics. Springer Netherlands, 2016. http://dx.doi.org/10.1007/978-94-017-7543-4_10.

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Dong, Nian, Lin Shi, Chengshui Chen, Wenhuan Ma, and Xiangdong Wang. "Clinical Epigenetics and Epigenomics." In Translational Bioinformatics. Springer Netherlands, 2016. http://dx.doi.org/10.1007/978-94-017-7543-4_5.

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Lempiäinen, Harri, Raphaëlle Luisier, Arne Müller, et al. "Epigenomics - Impact for Drug Safety Sciences." In Toxicology and Epigenetics. John Wiley & Sons, Ltd, 2012. http://dx.doi.org/10.1002/9781118349045.ch19.

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Umashankar, V., and S. Gurunathan. "Databases and Tools for Computational Epigenomics." In Toxicology and Epigenetics. John Wiley & Sons, Ltd, 2012. http://dx.doi.org/10.1002/9781118349045.ch30.

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Yadav, Chandra Bhan, Garima Pandey, Mehanathan Muthamilarasan, and Manoj Prasad. "Epigenetics and Epigenomics of Plants." In Plant Genetics and Molecular Biology. Springer International Publishing, 2018. http://dx.doi.org/10.1007/10_2017_51.

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Carmona, F. Javier, and Manel Esteller. "Human Cancer Epigenetics." In Environmental Epigenomics in Health and Disease. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-36827-1_13.

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Hawkins, R. David, and Bing Ren. "Epigenetics of Pluripotency." In Environmental Epigenomics in Health and Disease. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-23380-7_9.

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Sartor, Maureen A., Dana C. Dolinoy, Laura S. Rozek, and Gilbert S. Omenn. "Bioinformatics for High-Throughput Toxico-Epigenomics Studies." In Toxicology and Epigenetics. John Wiley & Sons, Ltd, 2012. http://dx.doi.org/10.1002/9781118349045.ch28.

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Conference papers on the topic "Epigenomics and epigenetics"

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Tomar, Tushar, Nicolette G. Alkema, Gert Jan Meersma, et al. "Abstract B19: Genome-wide integrated epigenomics identifies FZD-X as novel modulator for platinum sensitivity in high-grade serous ovarian cancer." In Abstracts: AACR Special Conference: Chromatin and Epigenetics in Cancer; September 24-27, 2015; Atlanta, GA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.chromepi15-b19.

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Chung, Chan, Stefan Sweha, Drew Pratt, et al. "Abstract PR02: Integrated metabolic and epigenomic reprograming by H3K27M mutations in diffuse intrinsic pontine gliomas." In Abstracts: AACR Special Virtual Conference on Epigenetics and Metabolism; October 15-16, 2020. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.epimetab20-pr02.

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Mitra, Sheetal A., Anirban P. Mitra, Jonathan D. Buckley, et al. "Abstract PR04: Genomic and epigenomic interactions of an Ewing sarcoma-specific long noncoding RNA." In Abstracts: AACR Special Conference on Chromatin and Epigenetics in Cancer - June 19-22, 2013; Atlanta, GA. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.cec13-pr04.

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Labbé, David P., Giorgia Zadra, Ericka M. Ebot, et al. "Abstract A10: High-fat diet enhances MYC-driven prostate cancer through epigenomic and metabolomic rewiring." In Abstracts: AACR Special Conference: Chromatin and Epigenetics in Cancer; September 24-27, 2015; Atlanta, GA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.chromepi15-a10.

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Yan Zhang, Jangzhong Su, Di Yu, Qiong Wu, and Haidan Yan. "EpiDiff: Entropy-based quantitative identification of differential epigenetic modification regions from epigenomes." In 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2013. http://dx.doi.org/10.1109/embc.2013.6609585.

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Vaz, Michelle, Stephen Y. Hwang, Ashwini Patil, Hariharan Easwaran, and Stephen B. Baylin. "Abstract B18: Chronic cigarette smoke exposure of bronchial epithelial cells induces progressive epigenomic changes leading to early steps of transformation." In Abstracts: AACR Special Conference: Chromatin and Epigenetics in Cancer; September 24-27, 2015; Atlanta, GA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.chromepi15-b18.

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Mills, Jamie N., and Stephen P. Ethier. "Abstract 2405: The 8p11 amplicon oncogenes ASH2L and NSD3 alter the epigenomic landscape and provide the foundation for novel application of epigenetic therapy in luminal B breast cancers." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-2405.

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