Academic literature on the topic 'Epilepsie gnd'

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Journal articles on the topic "Epilepsie gnd"

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Jokeit, Hennric, and Thomas Grunwald. "Epilepsie und Ged�chtnisbeeintr�chtigungen." Zeitschrift f�r Epileptologie 16, no. 2 (2003): 137–43. http://dx.doi.org/10.1007/s10309-003-0012-x.

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Malter, Michael P. "Epilepsie mit Antikörpern gegen Glutamat-Decarboxylase (GAD)." Zeitschrift für Epileptologie 33, no. 4 (2020): 303–5. http://dx.doi.org/10.1007/s10309-020-00363-3.

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Frerker, Bernd, Marco Rohde, Steffen Müller, Christian G. Bien, Rüdiger Köhling, and Timo Kirschstein. "Distinct Effects of Stereotactically Injected Human Cerebrospinal Fluid Containing Glutamic Acid Decarboxylase Antibodies into the Hippocampus of Rats on the Development of Spontaneous Epileptic Activity." Brain Sciences 10, no. 2 (2020): 123. http://dx.doi.org/10.3390/brainsci10020123.

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Background: The conversion of glutamic acid into γ-aminobutyric acid (GABA) is catalyzed by the glutamic acid decarboxylase (GAD). Antibodies against this enzyme have been described in neurological disorders, but the pathophysiological role of these antibodies is still poorly understood. We hypothesized that anti-GAD autoantibodies could diminish the GABA content in the slice and facilitate epileptic activity. Methods: Cerebrospinal fluids (CSF) from two patients containing anti-GAD (A and B) were injected into the rat hippocampus in vivo. Hippocampal slices were prepared for electrophysiologi
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UTHAYAKUMAR, R., and D. EASWARAMOORTHY. "EPILEPTIC SEIZURE DETECTION IN EEG SIGNALS USING MULTIFRACTAL ANALYSIS AND WAVELET TRANSFORM." Fractals 21, no. 02 (2013): 1350011. http://dx.doi.org/10.1142/s0218348x13500114.

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This paper explores the three different methods to explicitly recognize the healthy and epileptic EEG signals: Modified, Improved, and Advanced forms of Generalized Fractal Dimensions (GFD). The newly proposed scheme is based on GFD and the discrete wavelet transform (DWT) for analyzing the EEG signals. First EEG signals are decomposed into approximation and detail coefficients using DWT and then GFD values of the original EEGs, approximation and detail coefficients are computed. Significant differences are observed among the GFD values of the healthy and epileptic EEGs allowing us to classify
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., Lalchand, Santosh Kumar, Shahnaz Shah, Amjad Ali Qureshi, Tazeem Hussain, and Amanullah Bhutto. "Prevalence of Depression and Generalized Anxiety Disorder in the Epileptic Adults: A Case-Control Study." Pakistan Journal of Medical and Health Sciences 16, no. 7 (2022): 788–89. http://dx.doi.org/10.53350/pjmhs22167788.

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Aims: The present study aims the determination the frequency of generalized anxiety disorder (GAD) and depression in epileptic individuals and its association with the duration of the disease and frequency of episodes of seizures. Study type: A case-control study Place and Duration: This study was conducted at Ghulam Mohammad Mahar Medical College Sukkur SMBBMU Larkana from February 2021 to February 2022 Methodology: A total of 110 individuals were considered in the study. All of them were young males with a mean age of 23.2±2.5 years. A total of 55 participants were diagnosed with cases of ep
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Leslie, Ariel, and Jianzhong Su. "Modeling and simulation of a network of neurons regarding Glucose Transporter Deficiency induced epileptic seizures." Electronic Research Archive 30, no. 5 (2022): 1813–35. http://dx.doi.org/10.3934/era.2022092.

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<abstract><p>Epilepsy is a complex phenomena of a system of highly intensive and synchronized neurons simultaneously firing which can be traced to spatial and temporal patterns. Seizures are a well known physical feature for all types of epileptic disorders. The rhythms, patterns, and oscillatory dynamics explain the mechanistic nature of neurons especially in absence seizures. Previous models such as Wilson-Cowan (1973), introduced brain models showing the dynamics of a network of neurons consisting of excitatory and inhibitory neurons. Taylor et al. (2014) then adapted the Wilson
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Sotgiu, Stefano, Alessandro Consolaro, Susanna Casellato, Francesc Graus, and Paolo Picco. "Anti-GAD epileptic encephalopathy in a toddler with Parry-Romberg syndrome." Neurological Sciences 41, no. 3 (2019): 705–8. http://dx.doi.org/10.1007/s10072-019-04187-6.

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Baykal, Dilek. "Epilepsili Gebe ve Gebe Olmayan Kadınların Yaşam Kalitesi ve Evlilik Uyumunun Karşılaştırılması." Gevher Nesibe Journal, IESDR 5, no. 6 (2020): 36–44. http://dx.doi.org/10.46648/gnj.56.

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Leem, Eunju, Sehwan Kim, Chanchal Sharma, et al. "Inhibition of Granule Cell Dispersion and Seizure Development by Astrocyte Elevated Gene-1 in a Mouse Model of Temporal Lobe Epilepsy." Biomolecules 14, no. 3 (2024): 380. http://dx.doi.org/10.3390/biom14030380.

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Although granule cell dispersion (GCD) in the hippocampus is known to be an important feature associated with epileptic seizures in temporal lobe epilepsy (TLE), the endogenous molecules that regulate GCD are largely unknown. In the present study, we have examined whether there is any change in AEG-1 expression in the hippocampus of a kainic acid (KA)-induced mouse model of TLE. In addition, we have investigated whether the modulation of astrocyte elevated gene-1 (AEG-1) expression in the dentate gyrus (DG) by intracranial injection of adeno-associated virus 1 (AAV1) influences pathological ph
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Neuray, Caroline, Reza Maroofian, Marcello Scala, et al. "Early-infantile onset epilepsy and developmental delay caused by bi-allelic GAD1 variants." Brain 143, no. 8 (2020): 2388–97. http://dx.doi.org/10.1093/brain/awaa178.

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Abstract Gamma-aminobutyric acid (GABA) and glutamate are the most abundant amino acid neurotransmitters in the brain. GABA, an inhibitory neurotransmitter, is synthesized by glutamic acid decarboxylase (GAD). Its predominant isoform GAD67, contributes up to ∼90% of base-level GABA in the CNS, and is encoded by the GAD1 gene. Disruption of GAD1 results in an imbalance of inhibitory and excitatory neurotransmitters, and as Gad1−/− mice die neonatally of severe cleft palate, it has not been possible to determine any potential neurological dysfunction. Furthermore, little is known about the conse
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Books on the topic "Epilepsie gnd"

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Wallace, Sheila J., and Kevin Farrell. Epilepsy in Children. Taylor & Francis Group, 2004.

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Winter, Jerrold. Our Love Affair with Drugs. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780190051464.001.0001.

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Prescription, illicit, and recreational drugs touch all of our lives yet a basic understanding of these chemicals is largely absent among Americans. Jerrold Winter offers a comprehensive account of psychoactive drugs, chemicals which influence our brains in myriad ways. Manifestations of their influence on the brain are quite varied. There may be the comfort provided by opioids to those who are dying or in pain or, in everyday life, the surge of contentment for the users of caffeine, nicotine, heroin, alcohol, or marijuana upon the taking of their drug of choice. Turning to the more exotic, a
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Book chapters on the topic "Epilepsie gnd"

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Reuber, Markus, Steven C. Schachter, Christian E. Elger, and Ulrich Altrup. "Epilepsy Research." In Epilepsy Explained. Oxford University PressNew York, NY, 2009. http://dx.doi.org/10.1093/oso/9780195379532.003.0006.

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Abstract The word “epilepsy” was first used by Hippocrates over 2,000 years ago. Translated into English, it means something like “surprise attack.” Hippocrates described epileptic seizures in a very detailed way, although his insights were forgotten in later centuries. It was often thought that people with epilepsy were possessed by demons or the devil. Treatment was often quite drastic. If treatment killed people, it was said that the demons were too strong. However, some cultures also considered epilepsy a “sacred disease,” thinking that people were close to God during a seizure. Over many
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Bernasconi, R., P. Martin, A. F. Steulet, C. Portet, T. Leonhardt, and M. Schmutz. "Effects of benzodiazepine receptor ligands with different intrinsic activities on seizures induced by inhibition of GAD." In Neurotransmitters in Epilepsy. Elsevier, 1992. http://dx.doi.org/10.1016/b978-0-444-89710-7.50017-3.

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Schachter, Steven C., Kaarkuzhali Babu Krishnamurthy, and Deborah T. Combs Cantrell. "36." In Epilepsy in Our Lives. Oxford University PressNew York, NY, 2007. http://dx.doi.org/10.1093/oso/9780195330861.003.0036.

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Abstract I am very blessed to have God in my life, first of all, and a wonderful spouse. My family relationships have not been affected by epilepsy. The last time that I had a major episode with epilepsy was 20 years ago. My husband never even knew that I had epilepsy. I kept it from him until the seizures happened. I was taken to the hospital, and that is where my husband found out. He was surprised—but also wonderful—about it and did not allow it to affect our marriage.
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Schachter, Steven C., Kaarkuzhali Babu Krishnamurthy, and Deborah T. Combs Cantrell. "29." In Epilepsy in Our Lives. Oxford University PressNew York, NY, 2007. http://dx.doi.org/10.1093/oso/9780195330861.003.0029.

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Abstract A new adventure for me now is menopause! How will I know if symptoms are due to seizure activity, side effects of medication, or hormonal changes? Thank God for good doctors, good friends, and a wonderful family.
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Schachter, Steven C., Kaarkuzhali Babu Krishnamurthy, and Deborah T. Combs Cantrell. "34." In Epilepsy in Our Lives. Oxford University PressNew York, NY, 2007. http://dx.doi.org/10.1093/oso/9780195330861.003.0034.

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Abstract Epilepsy was like a veil through which I saw myself, life, and even the God for whom I sought to live. People who loved me always surrounded me, but I felt less than acceptable, unable to truly appreciate their love, and certainly unable to fathom why I was loved. For years I had felt that seizures put up the barriers of fear and shame. I recognized, finally, that something within me was a blockage to inner peace, and sought help in therapy.
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Schachter, Steven C., Kaarkuzhali Babu Krishnamurthy, and Deborah T. Combs Cantrell. "44." In Epilepsy in Our Lives. Oxford University PressNew York, NY, 2007. http://dx.doi.org/10.1093/oso/9780195330861.003.0044.

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Abstract When I first sat down to write this, I believed I had nothing to contribute. I have always tried to live my life as though epilepsy wasn’t part of the equation. But I found myself saying ‘‘except for’’ a lot. I see epilepsy from two perspectives. My cousin, Mary Anne, had a very severe case, worse than me. I hate to admit that before my own epilepsy surfaced, I would see my cousin go into seizures and I looked upon her with pity and some indifference, believing that somehow she had caused this to happen, and after all, God punished the evil. Although I believed she had been punished e
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Gentry, Matthew S., Kia H. Markussen, Ramon C. Sun, and Craig W. Vander Kooi. "Treating Lafora Disease with an Antibody-Enzyme Fusion." In Jasper's Basic Mechanisms of the Epilepsies, 5th ed., edited by Antonio V. Delgado-Escueta, José M. Serratosa, and Berge A. Minassian. Oxford University PressNew York, 2024. http://dx.doi.org/10.1093/med/9780197549469.003.0055.

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Abstract Lafora disease (LD) is a horrendous progressive myoclonic epilepsy that strikes healthy teenagers and leads to ever-worsening seizures with no relief from antiepileptic drugs; it then transitions to rapid dementia that ends in death typically after 10 years of onset. LD is the result of mutations in either the EPM2A or EPM2B/NHLRC1 gene that encodes the glycogen phosphatase laforin or the E3 ubiquitin ligase malin, respectively. A hallmark of LD is cytoplasmic, aberrant glycogen-like aggregates called Lafora bodies (LBs); thus, LD is also classified as a glycogen storage disease (GSD)
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Pattison, George. "Unknowing." In A Philosophy of Prayer. Fordham University Press, 2024. https://doi.org/10.5422/fordham/9781531506827.003.0002.

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The Western Christian tradition has acknowledged a dimension of “unknowing” as central to the Christian God-relationship, such that the desire of love has greater import than the desire for knowledge. A classic exposition of this view is the medieval tract The Cloud of Unknowing, which also questions the idea of a direct “experience” of God. In the modern period this is shown to be present in Kierkegaard’s upbuilding discourses, which also introduce the theme of temporality in a way that further qualifies claims of direct “experience”. An extreme version of the claim that the self is “decreate
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Ogunniyi, Adesola. "Global evidence generation." In Oxford Textbook of Neurologic and Neuropsychiatric Epidemiology, edited by Carol Brayne, Valery L. Feigin, Lenore J. Launer, and Giancarlo Logroscino. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198749493.003.0044.

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Disparities in the distribution of neurological and mental health disorders (NMHD) in different regions of the world can provide clues on the putative risk factors while providing basis for intervention strategies. This chapter utilizes the Global Burden of Diseases (GBD) data and the disability adjusted life years (DALY) calculations in the different World Health Organization (WHO) regions to adduce reasons for the peculiarities observed. The focus is on the most common NMHD, particularly those for which preventive strategies are likely to result in improved health outcomes for the majority o
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Goldberg, Ann. "Religious Madness in the Vormärz : Culture, Politics, and the Professionalization of Psychiatry." In Sex, Religion, and the Making of Modern Madness. Oxford University Press, 1999. http://dx.doi.org/10.1093/oso/9780195125818.003.0007.

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In 1849 Germany’s leading psychiatric journal reported a curious “illness” that, “like a plague,” had swept through a number of rural Swedish communities: young girls subject to an “involuntary drive to preach.” The “preaching illness” began with symptoms of a “strongly-felt awakening towards repentance and improvement,” headaches, and burning in the chest. It then progressed to “automatic convulsions” and visions, which the girls “imagine are the effects of God’s spirit.” In this state, they preached a message admonishing against sin—against dancing, drinking, card-playing, and other depraved
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Conference papers on the topic "Epilepsie gnd"

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Faccioli, Andrea Matheus, and Nágila Raquel Teixeira Damasceno. "Association between nutritional status of pediatric patients with refractory epilepsy and clinical response to the ketogenic diet." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.498.

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Background: The ketogenic diet (KD) is a high-fat, low-carbohydrate diet, prescribed for pediatric patients with refractory epilepsy. Although effective, the response to KD depends on factors that must be identified. Objectives: to evaluate the impact of nutritional status of pediatric patients on the KD clinical response. Methods: This is a retrospective longitudinal study based on the follow-up of patients with refractory epilepsy (ICr-FMUSP) in treatment with KD after 3 (T1) and 6 months (T2). At baseline, patients were split into Eutrophic group (EG; BMI ≤25 kg/m2) and Non-Eutrophic group
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Yagnik, Deepti, Josephine Chan, Ben McGettigan, Andrew Laycock, and Allycia MacDonald. "3121 New onset refractory epilepsy (NORSE) secondary to anti-glutamic acid decarboxylase (anti-GAD) and anti-Hu antibodies related paraneoplastic encephalitis from lymphocyte-rich thymoma." In ANZAN Annual Scientific Meeting 2024 Abstracts. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/bmjno-2024-anzan.110.

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Kim, Jung Hwan, Garrett Astary, Svetlana Kantorovich, Thomas H. Mareci, Paul R. Carney, and Malisa Sarntinoranont. "Voxelized 3D Computational Transport Model of Infusions Into the Ventral Hippocampus: Comparison With Experimental Studies." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53444.

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Convection enhanced delivery (CED) is a promising local delivery technique for overcoming the blood brain barrier (BBB) and treating diseases of the central nervous system (CNS). For CED, infusate is infused directly into brain tissue and the drug agent is spread through the extracellular space, which is considered highly tortuous porous media. Previous studies have indicated that the infusion of therapeutic agents into the hippocampus is a potential treatment method for epilepsy [1]. In this study, a 3D interstitial transport modeling approach is presented in which tissue properties and anato
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