Academic literature on the topic 'Epithelial-mesenchymal transition'

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Journal articles on the topic "Epithelial-mesenchymal transition"

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Klymkowsky, Michael W., and Pierre Savagner. "Epithelial-Mesenchymal Transition." American Journal of Pathology 174, no. 5 (2009): 1588–93. http://dx.doi.org/10.2353/ajpath.2009.080545.

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Han, Myung Woul, Jong Cheol Lee, Young Min Kim, et al. "Epithelial-Mesenchymal Transition." Otolaryngology–Head and Neck Surgery 152, no. 1 (2014): 80–86. http://dx.doi.org/10.1177/0194599814556061.

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Zavadil, Jiri, John Haley, Raghu Kalluri, Senthil K. Muthuswamy, and Erik Thompson. "Epithelial-Mesenchymal Transition." Cancer Research 68, no. 23 (2008): 9574–77. http://dx.doi.org/10.1158/0008-5472.can-08-2316.

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Radisky, D. C. "Epithelial-mesenchymal transition." Journal of Cell Science 118, no. 19 (2005): 4325–26. http://dx.doi.org/10.1242/jcs.02552.

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Kamlund, Sofia, Birgit Janicke, Kersti Alm, Robert L. Judson-Torres, and Stina Oredsson. "Quantifying the Rate, Degree, and Heterogeneity of Morphological Change during an Epithelial to Mesenchymal Transition Using Digital Holographic Cytometry." Applied Sciences 10, no. 14 (2020): 4726. http://dx.doi.org/10.3390/app10144726.

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Cells in complex organisms can transition between epithelial and mesenchymal phenotypes during both normal and malignant physiological events. These two phenotypes are not binary, but rather describe a spectrum of cell states along an axis. Mammalian cells can undergo dynamic and heterogenous bidirectional interconversions along the epithelial–mesenchymal phenotypic (EMP) spectrum, and such transitions are marked by morphological change. Here, we exploit digital holographic cytometry (DHC) to develop a tractable method for monitoring the degree, kinetics, and heterogeneity of epithelial and me
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Sharma, Anil K., and Rolf D. Hubmayr. "Epithelial to mesenchymal transition." Critical Care Medicine 40, no. 2 (2012): 682–83. http://dx.doi.org/10.1097/ccm.0b013e318232d1a8.

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Luft, Friedrich C. "Targeting epithelial–mesenchymal transition." Journal of Molecular Medicine 93, no. 7 (2015): 703–5. http://dx.doi.org/10.1007/s00109-015-1302-2.

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Manfioletti, Guidalberto, and Monica Fedele. "Epithelial–Mesenchymal Transition (EMT)." International Journal of Molecular Sciences 24, no. 14 (2023): 11386. http://dx.doi.org/10.3390/ijms241411386.

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Shcherbakov, V., T. Ryabichenko, G. Skosyreva, and A. Trunov. "EPITHELIAL-MESENCHYMAL AND MESENCHYMAL-EPITHELIAL TRANSITION, PATHOGENESIS, REGULATION, THERAPY." Problems in oncology 64, no. 1 (2018): 62–72. http://dx.doi.org/10.37469/0507-3758-2018-64-1-62-72.

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The review considered the issues of epithelial-mesenchymal transition (EMT) and its role in inflammation, fibrosis, tumor growth. There were analyzed mechanisms and classification of EMT. A comparison of different forms of EMTs was performed. The important role of EMT in the formation of metastasis-initiating cells was noted. There were presented data on the role of fibroblasts in fibrosis of the lung, carcinogenesis. Stimulators and inhibitors of EMTs were summarized. There were considered intracellular paths that were associated with the development of the EMT under the influence of transfor
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Ishida, Mitsuaki, Akie Takebayashi, Fuminori Kimura, et al. "Induction of the epithelial-mesenchymal transition in the endometrium by chronic endometritis in infertile patients." PLOS ONE 16, no. 4 (2021): e0249775. http://dx.doi.org/10.1371/journal.pone.0249775.

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Background The purpose of the present study was to evaluate the relationship between chronic endometritis and the epithelial-mesenchymal transition in the endometrium of infertile patients in the implantation phase. Methods Endometrial biopsy specimens from 66 infertility patients were analyzed. The presence of chronic endometritis was investigated by immunostaining for CD138. Immunohistochemical staining for E-cadherin, N-cadherin, Slug, and Snail was performed, and the expression profiles were statistically analyzed according to the presence of chronic endometritis. When the loss of E-cadher
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Dissertations / Theses on the topic "Epithelial-mesenchymal transition"

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Qiao, Bin. "Epithelial-Mesenchymal Transition and Mesenchymal-Epithelial Transition in Oral Stem Cell Carcinogenesis." Thesis, Griffith University, 2011. http://hdl.handle.net/10072/367467.

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Oral squamous cell carcinoma (OSCC), derived from normal oral epithelium transformation, remains a major public health problem world-wide. The prognosis of OSCCs that occur on lips is good, while other sites of oral mucosa where OSCC appears are more progressive, invasive and metastatic. A small subset of cells within a malignant neoplasm, named cancer stem cells (CSCs) or tumour initiating cells are thought to be capable of initiating the neoplasm itself, and of driving its growth and recurrance after treatment. The precise origin of CSCs is an ambiguous issue at present. The first proposal o
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Robson, Ewan John Douglas. "Characterisation of epithelial-mesenchymal transition in murine mammary epithelial cells." Thesis, University of Cambridge, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.616130.

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Millanes, Romero Alba 1986. "Heterochromatin dynamics during epithelial-to-mesenchymal transition." Doctoral thesis, Universitat Pompeu Fabra, 2014. http://hdl.handle.net/10803/129339.

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Although heterochromatin is enriched with repressive traits, it is actively transcribed, giving rise to large amounts of non-coding RNAs. These transcripts are responsible for the formation and maintenance of heterochromatin, but little is known about how their transcription is regulated. In this thesis we show that Snail1 transcription factor represses mouse pericentromeric transcription and regulates heterochromatin organization through the action of the H3K4 deaminase LOXL2. Snail1 has a key role in epithelial-to-mesenchymal transition (EMT). We show that, also during this process, Sn
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Tan, E.-Jean. "Transcriptional and Epigenetic Regulation of Epithelial-Mesenchymal Transition." Doctoral thesis, Uppsala universitet, Ludwiginstitutet för cancerforskning, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-206120.

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The transforming growth factor beta (TGFβ) is a cytokine that regulates a plethora of cellular processes such as cell proliferation, differentiation, migration and apoptosis. TGFβ signals via serine/threonine kinase receptors and activates the Smads to regulate gene expression. Enigmatically, TGFβ has a dichotomous role as a tumor suppressor and a tumor promoter in cancer. At early stages of tumorigenesis, TGFβ acts as a tumor suppressor by exerting growth inhibitory effects and inducing apoptosis. However, at advanced stages, TGFβ contributes to tumor malignancy by promoting invasion and meta
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Cheung, Pak-yan, and 張柏欣. "Esophageal carcinogenesis: immortalization, transformation and epithelial-mesenchymal transition." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B41290379.

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Abdulla, Tariq. "Advances in modelling of epithelial to mesenchymal transition." Thesis, Loughborough University, 2013. https://dspace.lboro.ac.uk/2134/12744.

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Epithelial to Mesenchymal Transition (EMT) is a cellular transformation process that is employed repeatedly and ubiquitously during vertebrate morphogenesis to build complex tissues and organs. Cellular transformations that occur during cancer cell invasion are phenotypically similar to developmental EMT, and involve the same molecular signalling pathways. EMT processes are diverse, but are characterised by: a loss of cell-cell adhesion; a gain in cell-matrix adhesion; an increase in cell motility; the secretion of proteases that degrade basement membrane proteins; an increased resistance to a
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Cheung, Pak-yan. "Esophageal carcinogenesis : immortalization, transformation and epithelial-mesenchymal transition /." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B41290379.

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De, Arpan. "Circadian clock regulation of epithelial-mesenchymal and mesenchymal-epithelial transitions in glioma and breast cancer cells." Bowling Green State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1566494866910786.

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Ilter, Didem. "The Role of ERK2 in Regulating Epithelial-Mesenchymal Transition." Thesis, Harvard University, 2014. http://dissertations.umi.com/gsas.harvard:11407.

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Epithelial-mesenchymal transition (EMT) is a fundamental developmental program, which is believed to be reactivated during the progression of in situ carcinoma to aggressive metastatic cancers. Ras-ERK pathway has been shown to play a crucial role in EMT. We have previously shown that ERK2, but not ERK1, is necessary for RasV12-induced EMT and overexpression of ERK2 is sufficient to promote EMT. ERK2 promotes EMT by regulating several factors, including the upregulation of transcription factors ZEB1/2. ZEB1/2 repress expression of E-cadherin, which is necessary for polar epithelial tissue form
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Dubois-Marshall, Sylvie. "Understanding epithelial to mesenchymal transition in human breast cancer." Thesis, University of Edinburgh, 2012. http://hdl.handle.net/1842/24541.

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Background and aims: Increasing evidence suggests that epithelial to mesenchymal transition (EMT) has a key role in breast cancer progression, underlying invasion, metastatic dissemination and acquisition of therapeutic resistance. However, this role is predominantly inferred from in vitro and animal studies and controversy regarding EMT in human cancer remains. This thesis has two principle aims. Firstly, to clarify the role of EMT in human breast cancer at the protein level. Secondly, to develop a three-dimensional in vitro assay to investigate cell invasion. Experimental Design: Two indepen
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Books on the topic "Epithelial-mesenchymal transition"

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Campbell, Kyra, and Eric Theveneau, eds. The Epithelial-to Mesenchymal Transition. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-0779-4.

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Pierre, Savagner, ed. Rise and fall of epithelial phenotype: Concepts of epithelial-mesenchymal transition. Landes Bioscience/Eurekah.com, 2005.

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Cheung, Albert. Pax3 and PAX3/FKHR induces cell aggregation and morphogenic mesenchymal-epithelial transition. National Library of Canada, 2002.

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Muthuswamy, Senthil, John Douglas Haley, and Raghu Kalluri. Abstracts of papers presented at the 2008 meeting on epithelial-mesenchymal transition: March 17-March 20, 2008. Cold Spring Harbor Laboratory, 2008.

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Sivasubramaniyan, Kavitha. A novel antibody directed against SSEA-4 defines spontaneous epithelial-to-mesenchymal cell transition in human prostate cancer. s.n.], 2014.

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Sŏnggyun'gwan Taehakkyo (Seoul, Korea). Sanhak Hyŏmnyŏktan. TGF-beta e ŭihan oncogenic Epithelial-Mesenchymal Transition (EMT) yubal inja rosŏ hangsanhwa tanbaekchildŭl ŭi yŏkhal kyumyŏng kwa kijŏn yŏn'gu =: Molecular characterization of distinct roles of anti-oxidative proteins and their signaling mechanism in the oncogenic epithelial-mesenchymal transition by TGF-beta. Pogŏn Pokchi Kajokpu, 2009.

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Thompson, Erik W. Epithelial-mesenchymal transitions: new advances in development, fibrosis and cancer: 9 tables. Karger, 2011.

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Campbell, Kyra, and Eric Theveneau. Epithelial-To Mesenchymal Transition: Methods and Protocols. Springer, 2021.

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Campbell, Kyra, and Eric Theveneau. Epithelial-To Mesenchymal Transition: Methods and Protocols. Springer, 2020.

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Savagner, Pierre. Rise and Fall of Epithelial Phenotype: Concepts of Epithelial-Mesenchymal Transition. Springer London, Limited, 2008.

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Book chapters on the topic "Epithelial-mesenchymal transition"

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Rajasekaran, Ayyappan K., and Sigrid A. Langhans. "Epithelial-to-Mesenchymal Transition." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27841-9_1962-2.

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Miki, Toru, Randa Hilal-Dandan, Laurence L. Brunton, et al. "Epithelial to Mesenchymal Transition." In Encyclopedia of Signaling Molecules. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_100399.

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Rajasekaran, Ayyappan K., and Sigrid A. Langhans. "Epithelial-to-Mesenchymal Transition." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-46875-3_1962.

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Rajasekaran, Ayyappan K., and Sigrid A. Rajasekaran. "Epithelial-to-Mesenchymal Transition." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-16483-5_1962.

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Choi, Yoon Jin, and Hyeon Jang. "Gastric Cancer: Epithelial Mesenchymal Transition." In Helicobacter pylori. Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-287-706-2_25.

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Kim, Nayoung, Yoon Jin Choi, and Hyeon Jang. "Gastric Cancer: Epithelial-Mesenchymal Transition." In Helicobacter pylori. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-97-0013-4_26.

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Karakas, E., J. Waldmann, G. Feldmann, et al. "Epithelial-mesenchymal transition in parathyroid neoplasms." In Deutsche Gesellschaft für Chirurgie. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-00625-8_16.

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Schmalhofer, Otto, Simone Brabletz, and Thomas Brabletz. "Epithelial-Mesenchymal Transition in Colorectal Cancer." In Metastasis of Colorectal Cancer. Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-8833-8_6.

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Mittal, Vivek. "Epithelial Mesenchymal Transition in Aggressive Lung Cancers." In Lung Cancer and Personalized Medicine: Novel Therapies and Clinical Management. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-24932-2_3.

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Wu, Yadi, and Binhua P. Zhou. "Epithelial–Mesenchymal Transition in Development and Diseases." In The Tumor Microenvironment. Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-6615-5_9.

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Conference papers on the topic "Epithelial-mesenchymal transition"

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Wuerthwein, Thomas, Anke Bonse, Ramon Droop, et al. "Advanced hyperspectral SRS imaging for studying epithelial-mesenchymal transition in cancer metastasis." In Label-free Biomedical Imaging and Sensing (LBIS) 2025, edited by Natan T. Shaked and Oliver Hayden. SPIE, 2025. https://doi.org/10.1117/12.3042720.

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Brockmeyer, T., L. Pham, K. Zscheppang, et al. "Epithelial-Mesenchymal Transition in Fetal Type-II Epithelial Cells." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5299.

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Wu, Tsung-Hsien, Jen-I. Liang, Yu-Wei Chiu, Ming-Long Yeh, and Chia-Hsin Chen. "Mechanical quantification of the Epithelial mesenchymal transition." In 2011 IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS). IEEE, 2011. http://dx.doi.org/10.1109/nems.2011.6017391.

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Yamauchi, Y., T. Kohyama, S. Kamitani, et al. "Epithelial Mesenchymal Transition Modulates the Cell Proliferation of Lung Epithelial Cells." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5306.

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Nagel, D., R. M. Kottmann, and D. Hocking. "Elastin Degradation Products Cause Epithelial to Mesenchymal Transition." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2187.

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Zielinski, Rachel, Cosmin Mihai, and Samir Ghadiali. "Multi-Scale Modeling of Cancer Cell Migration and Adhesion During Epithelial-to-Mesenchymal Transition." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53511.

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Cancer is a leading cause of death in the US, and tumor cell metastasis and secondary tumor formation are key factors in the malignancy and prognosis of the disease. The regulation of cell motility plays an important role in the migration and invasion of cancer cells into surrounding tissues. The primary modes of increased motility in cancerous tissues may include collective migration of a group of epithelial cells during tumor growth and single cell migration of mesenchymal cells after detachment from the primary tumor site [1]. In epithelial cancers, metastasizing cells lose their cell-cell
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Sporn, Peter H. S., Naizhen Wang, and Aisha Nair. "MicroRNA Profile Of Epithelial-Mesenchymal Transition In Normal Human Bronchial Epithelial Cells." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a2488.

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Mason, CA, та LS Brown. "Acetaldehyde Promoted Epithelial-Mesenchymal Transition through Increased TGF-β." У American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a4971.

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Weinberg, R. "Breast Cancer Stem Cells and the Epithelial-Mesenchymal Transition." In Abstracts: Thirty-Second Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 10‐13, 2009; San Antonio, TX. American Association for Cancer Research, 2009. http://dx.doi.org/10.1158/0008-5472.sabcs-09-a1-1.

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Inayat, Huma, Scott Tsai, and Andras Kapus. "Investigation Of Epithelial-To-Mesenchymal Transition Through Microcontact Printing." In 2018 Canadian Society for Mechanical Engineering (CSME) International Congress. York University Libraries, 2018. http://dx.doi.org/10.25071/10315/35348.

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Reports on the topic "Epithelial-mesenchymal transition"

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Krause, Silva. Promotion of Epithelial to Mesenchymal Transition by Hyaluronan. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada462484.

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Krause, Silva. Promotion of Epithelial to Mesenchymal Transition by Hyaluronan. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada463843.

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Kah, Kong J. Signature and Mechanism of the Epithelial-to-Mesenchymal Transition. Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ada541945.

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Thompson, Erik W. Functional Genomics for Epithelial-Mesenchymal Transition in Breast Cancer. Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ada542255.

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Kah, Kong J. Signature and Mechanism of the Epithelial-to-Mesenchymal Transition. Defense Technical Information Center, 2009. http://dx.doi.org/10.21236/ada504655.

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Tyner, Angela L. Regulation of the Epithelial-Mesenchymal Transition in Prostate Cancer. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada594294.

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Kah, Kong J. Signature and Mechanism of the Epithelial-to-Mesenchymal Transition. Defense Technical Information Center, 2011. http://dx.doi.org/10.21236/ada549247.

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Thompson, Erik. Functional Genomics for Epithelial-Mesenchymal Transition in Breast Cancer. Defense Technical Information Center, 2011. http://dx.doi.org/10.21236/ada554588.

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Range, Ryan C., and Davis R. McClay. A Normal Epithelial-Mesenchymal Transition as a Model for Studying Metastatic Onset. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada416671.

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Keckesova, Zuzana. The Role of Epithelial-Mesenchymal Transition in the Formation of Normal and Neoplastic Mammary Epithelial Stem Cells. Defense Technical Information Center, 2011. http://dx.doi.org/10.21236/ada554127.

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