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Journal articles on the topic 'Epoxy fatty acids'

Author: Grafiati

Published: 4 June 2021

Last updated: 6 February 2022

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1

Qian, Chen, and Li Zu-Yi. "Lipase catalyzed synthesis of epoxy-fatty acids." Chinese Journal of Chemistry 18, no. 2 (2010): 247–48. http://dx.doi.org/10.1002/cjoc.20000180220.

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2

Ortiz, Pablo, Richard Vendamme, and Walter Eevers. "Fully Biobased Epoxy Resins from Fatty Acids and Lignin." Molecules 25, no. 5 (2020): 1158. http://dx.doi.org/10.3390/molecules25051158.

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The use of renewable resources for plastic production is an imperious need for the reduction of the carbon footprint and the transition towards a circular economy. With that goal in mind, fully biobased epoxy resins have been designed and prepared by combining epoxidized linseed oil, lignin, and a biobased diamine derived from fatty acid dimers. The aromatic structures in lignin provide hardness and strength to an otherwise flexible and breakable epoxy resin. The curing of the system was investigated by infrared spectroscopy and differential scanning calorimetry (DSC). The influence of the dif

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3

Singh, S., S. Thomaeus, M. Lee, A. Green, and S. Stymne. "Inhibition of polyunsaturated fatty acid accumulation in plants expressing a fatty acid epoxygenase." Biochemical Society Transactions 28, no. 6 (2000): 940–42. http://dx.doi.org/10.1042/bst0280940.

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Earlier, we described the isolation of a Crepis palaestina cDNA (Cpal2) which encoded a Δ12-epoxygenase that could catalyse the synthesis of 12,13-epoxy-cis-9-octadecenoic acid (18:1E) from linoleic acid (18:2). When the Cpal2 gene was expressed under the control of a seed-specific promoter in Arabidopsis plants were able to accumulate small amounts 18:1E and 12,13-epoxy-cis-9,15-octadec-2-enoic acid in their seed lipids. In this report we give results obtained from a detailed analysis of transgenic Arabidopsis plants containing the Cpal2 gene. The seeds from these plants accumulate varying le

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4

Eggink, Gerrit, Pieter de Waard, and Gern N. M. Huijberts. "Formation of novel poly(hydroxyalkanoates) from long-chain fatty acids." Canadian Journal of Microbiology 41, no. 13 (1995): 14–21. http://dx.doi.org/10.1139/m95-163.

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Poly(hydroxyalkanoates) (PHAs) were isolated from Pseudomonas aeruginosa 44T1 cultivated on euphorbia oil and castor oil. With the aid of 2-D proton NMR spectra and proton-detected multiple bond coherence NMR spectra the structures of the PHAs were determined. In addition to the usual PHA constituents (C6–C14 3-hydroxy fatty acids), PHAs formed from euphorbia oil contained Δ8,9-epoxy-3-hydroxy-5c-tetradecenoate, and probably Δ6,7-epoxy-3-hydroxydodecanoate and Δ4,5-epoxy-3-hydroxydecanoate. These novel constituents account for approximately 15% of the total amount of monomers and are clearly g

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5

Gilmer, Chad M., Christian Zvokel, Alexandra Vick, and Ned B. Bowden. "Separation of saturated fatty acids and fatty acid methyl esters with epoxy nanofiltration membranes." RSC Advances 7, no. 88 (2017): 55626–32. http://dx.doi.org/10.1039/c7ra11223h.

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6

Warner, Jeffrey, Josiah Hardesty, Kara Zirnheld, Craig McClain, Dennis Warner, and Irina Kirpich. "Soluble Epoxide Hydrolase Inhibition in Liver Diseases: A Review of Current Research and Knowledge Gaps." Biology 9, no. 6 (2020): 124. http://dx.doi.org/10.3390/biology9060124.

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Emerging evidence suggests that soluble epoxide hydrolase (sEH) inhibition is a valuable therapeutic strategy for the treatment of numerous diseases, including those of the liver. sEH rapidly degrades cytochrome P450-produced epoxygenated lipids (epoxy-fatty acids), which are synthesized from omega-3 and omega-6 polyunsaturated fatty acids, that generally exert beneficial effects on several cellular processes. sEH hydrolysis of epoxy-fatty acids produces dihydroxy-fatty acids which are typically less biologically active than their parent epoxide. Efforts to develop sEH inhibitors have made ava

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7

Velíšek, J., and K. Cejpek. "Biosynthesis of food constituents: Lipids. 1. Fatty acids and derivated compounds – a review." Czech Journal of Food Sciences 24, No. 5 (2011): 193–216. http://dx.doi.org/10.17221/3317-cjfs.

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This review article gives a survey of the principal biosynthetic pathways that lead to the most important common fatty acids and their derivatives occurring in foods and feeds. Fatty acids are further subdivided to saturated fatty acids and unsaturated fatty acids. This review is focused on the less common fatty acids including geometrical and positional isomers of unsaturated fatty acids, acetylenic fatty acids, branched-chain fatty acids, alicyclic fatty acids, epoxy fatty acids, hydroxy fatty acids, and oxo fatty acids. A survey is further given on the biosynthesis of the aliphatic very-lon

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8

Wilson, R., C. E. Fernie, C. M. Scrimgeour, K. Lyall, L. Smyth, and R. A. Riemersma. "Dietary epoxy fatty acids are absorbed in healthy women." European Journal of Clinical Investigation 32, no. 2 (2002): 79–83. http://dx.doi.org/10.1046/j.1365-2362.2002.00951.x.

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9

Mahmood, Chirag, Jehan D. Daulatabad, and Kallappa M. Hosamani. "Epoxy and cyclopropenoid fatty acids inAmaranthus paniculatus seed oil." Journal of the Science of Food and Agriculture 58, no. 1 (1992): 139–41. http://dx.doi.org/10.1002/jsfa.2740580123.

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10

Daulatabad, Chirag Mahmood Jehan D., Abdurrazzaque M. Mirajkar, Kallappa M. Hosamani, and Gouse Mohaddin M. Mulla. "Epoxy and cyclopropenoid fatty acids inSyzygium cuminii seed oil." Journal of the Science of Food and Agriculture 43, no. 1 (1988): 91–94. http://dx.doi.org/10.1002/jsfa.2740430111.

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11

Wagner, K., K. S. S. Lee, J. Yang, and B. D. Hammock. "Epoxy fatty acids mediate analgesia in murine diabetic neuropathy." European Journal of Pain 21, no. 3 (2016): 456–65. http://dx.doi.org/10.1002/ejp.939.

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12

Li, Runzhi, Keshun Yu, Tomoko Hatanaka, and David F. Hildebrand. "VernoniaDGATs increase accumulation of epoxy fatty acids in oil." Plant Biotechnology Journal 8, no. 2 (2010): 184–95. http://dx.doi.org/10.1111/j.1467-7652.2009.00476.x.

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13

Fang, Xiang, Neal L. Weintraub, Christine L. Oltman, et al. "Human coronary endothelial cells convert 14,15-EET to a biologically active chain-shortened epoxide." American Journal of Physiology-Heart and Circulatory Physiology 283, no. 6 (2002): H2306—H2314. http://dx.doi.org/10.1152/ajpheart.00448.2002.

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Cytochrome P-450 epoxygenase-derived epoxyeicosatrienoic acids (EETs) play an important role in the regulation of vascular reactivity and function. Conversion to the corresponding dihydroxyeicosatrienoic acids (DHETs) by soluble epoxide hydrolases is thought to be the major pathway of EET metabolism in mammalian vascular cells. However, when human coronary artery endothelial cells (HCEC) were incubated with 3H-labeled 14,15-EET, chain-shortened epoxy fatty acids, rather than DHET, were the most abundant metabolites. After 4 h of incubation, 23% of the total radioactivity remaining in the mediu

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14

Omonov, Tolibjon S., Ereddad Kharraz, and Jonathan M. Curtis. "The epoxidation of canola oil and its derivatives." RSC Advances 6, no. 95 (2016): 92874–86. http://dx.doi.org/10.1039/c6ra17732h.

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This work explores the epoxidation and subsequent acid catalyzed epoxy ring opening kinetics of canola oil (CanO), canola oil fatty acid methyl esters (CanFAME) and canola oil free fatty acids (CanFFA).

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15

Imig, John D., Wojciech K. Jankiewicz, and Abdul H. Khan. "Epoxy Fatty Acids: From Salt Regulation to Kidney and Cardiovascular Therapeutics." Hypertension 76, no. 1 (2020): 3–15. http://dx.doi.org/10.1161/hypertensionaha.120.13898.

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Epoxyeicosatrienoic acids (EETs) are epoxy fatty acids that have biological actions that are essential for maintaining water and electrolyte homeostasis. An inability to increase EETs in response to a high-salt diet results in salt-sensitive hypertension. Vasodilation, inhibition of epithelial sodium channel, and inhibition of inflammation are the major EET actions that are beneficial to the heart, resistance arteries, and kidneys. Genetic and pharmacological means to elevate EETs demonstrated antihypertensive, anti-inflammatory, and organ protective actions. Therapeutic approaches to increase

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16

Pan, Xiao, Partha Sengupta, and Dean C. Webster. "Novel biobased epoxy compounds: epoxidized sucrose esters of fatty acids." Green Chemistry 13, no. 4 (2011): 965. http://dx.doi.org/10.1039/c0gc00882f.

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17

de Kruijff, Goswinus H. M., Thorsten Goschler, Lukasz Derwich, Nicole Beiser, Oliver M. Türk, and Siegfried R. Waldvogel. "Biobased Epoxy Resin by Electrochemical Modification of Tall Oil Fatty Acids." ACS Sustainable Chemistry & Engineering 7, no. 12 (2019): 10855–64. http://dx.doi.org/10.1021/acssuschemeng.9b01714.

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18

Narra, Naganna, Badari Narayana Prasad Rachapudi, Sahithya Phani Babu Vemulapalli, and Padmaja V. Korlipara. "Lewis-acid catalyzed synthesis and characterization of novel castor fatty acid-based cyclic carbonates." RSC Advances 6, no. 31 (2016): 25703–12. http://dx.doi.org/10.1039/c6ra00880a.

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19

Fang, Xiang, Terry L. Kaduce, Mike VanRollins, Neal L. Weintraub, and Arthur A. Spector. "Conversion of epoxyeicosatrienoic acids (EETs) to chain-shortened epoxy fatty acids by human skin fibroblasts." Journal of Lipid Research 41, no. 1 (2000): 66–74. http://dx.doi.org/10.1016/s0022-2275(20)32075-7.

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20

Banaś, A., A. Dahlqvist, U. Ståhl, M. Lenman, and S. Stymne. "The involvement of phospholipid:diacylglycerol acyltransferases in triacylglycerol production." Biochemical Society Transactions 28, no. 6 (2000): 703–5. http://dx.doi.org/10.1042/bst0280703.

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We have characterized three CoA-independent types of enzyme, phospholipases, phospholipid: diacylglycerol acyltransferases (PDATs) and cholinephosphotransferases, responsible for the removal of unusual fatty acids from phosphatidylcholine (PC) in microsomal preparations from developing oil seeds. The metabolism of sn-2-[14C]acyl-PC was monitored in microsomal preparations from various oilseeds having either medium-chain, acetylenic, epoxy or hydroxy fatty acids as their major fatty acids in the oil. The results indicate that PDAT plays a major role in removing ricinoleic acid and vernolic acid

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21

Borgeat, Pierre. "Biochemistry of the lipoxygenase pathways in neutrophils." Canadian Journal of Physiology and Pharmacology 67, no. 8 (1989): 936–42. http://dx.doi.org/10.1139/y89-147.

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Three mammalian lipoxygenases have been reported to date. They catalyze the insertion of oxygen at positions 5, 12, and 15 of various 20-carbon polyunsaturated fatty acids. In the case of arachidonic acid, the immediate products are hydroperoxyeicosatetraenoic acids (HPETEs). HPETEs can undergo different transformations. One reaction is a reduction of the hydroperoxy group yielding the corresponding hydroxyeicosatetraenoic acids (HETEs). In the neutrophils, the major pathway of arachidonic acid metabolism is the 5-lipoxygenase. In these cells the 5-HPETE undergoes a cyclization reaction leadin

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22

Xu, Jiawen, Christophe Morisseau, Jun Yang, Dadala M. Mamatha, and Bruce D. Hammock. "Epoxide hydrolase activities and epoxy fatty acids in the mosquito Culex quinquefasciatus." Insect Biochemistry and Molecular Biology 59 (April 2015): 41–49. http://dx.doi.org/10.1016/j.ibmb.2015.02.004.

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23

Wan, Hong, Lars G. Blomberg, and Mats Hamberg. "Highly efficient separation of isomeric epoxy fatty acids by micellar electrokinetic chromatography." Electrophoresis 20, no. 1 (1999): 132–37. http://dx.doi.org/10.1002/(sici)1522-2683(19990101)20:1<132::aid-elps132>3.0.co;2-i.

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24

Rontani, J. F., B. Charriere, M. Petit, et al. "Degradation state of organic matter in surface sediments from the Southern Beaufort Sea: a lipid approach." Biogeosciences 9, no. 9 (2012): 3513–30. http://dx.doi.org/10.5194/bg-9-3513-2012.

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Abstract. For the next decades significant climatic changes should occur in the Arctic zone. The expected destabilisation of permafrost and its consequences for hydrology and plant cover should increase the input of terrigenous carbon to coastal seas. Consequently, the relative importance of the fluxes of terrestrial and marine organic carbon to the seafloor will likely change, strongly impacting the preservation of organic carbon in Arctic marine sediments. Here, we investigated the lipid content of surface sediments collected on the Mackenzie basin in the Beaufort Sea. Particular attention w

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25

Shikha, Deepti, P. K. Kamani, and M. C. Shukla. "Studies on synthesis of water-borne epoxy ester based on RBO fatty acids." Progress in Organic Coatings 47, no. 2 (2003): 87–94. http://dx.doi.org/10.1016/s0300-9440(02)00159-5.

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26

Pan, Xiao, Partha Sengupta, and Dean C. Webster. "High Biobased Content Epoxy–Anhydride Thermosets from Epoxidized Sucrose Esters of Fatty Acids." Biomacromolecules 12, no. 6 (2011): 2416–28. http://dx.doi.org/10.1021/bm200549c.

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27

Meesapyodsuk, Dauenpen, and Xiao Qiu. "A Peroxygenase Pathway Involved in the Biosynthesis of Epoxy Fatty Acids in Oat." Plant Physiology 157, no. 1 (2011): 454–63. http://dx.doi.org/10.1104/pp.111.178822.

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28

Atone, Jogen, Sung Hee Hwang, and Bruce D. Hammock. "Investigating the Effects of Epoxy Fatty Acids against LPS and Pesticide Induced Toxicity." FASEB Journal 34, S1 (2020): 1. http://dx.doi.org/10.1096/fasebj.2020.34.s1.08948.

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29

Yang, Zhen, Vieno Piironen, and Anna-Maija Lampi. "Epoxy and hydroxy fatty acids as non-volatile lipid oxidation products in oat." Food Chemistry 295 (October 2019): 82–93. http://dx.doi.org/10.1016/j.foodchem.2019.05.052.

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30

Agarwal, R., A. Rauf, M. Khan, J. Mustafa, and M. Ahmad. "Organoselenium-mediated cyclization of hydroxyolefinic fatty acids and m-CPBA oxidation of selenium-containing 1,4-epoxy acids." Journal of the American Oil Chemists' Society 67, no. 12 (1990): 932–36. http://dx.doi.org/10.1007/bf02541851.

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31

Wahby, Mohamed H., Ayman M. Atta, Yasser M. Moustafa, Abdelrahman O. Ezzat, and Ahmed I. Hashem. "Curing of Functionalized Superhydrophobic Inorganic/Epoxy Nanocomposite and Application as Coatings for Steel." Coatings 11, no. 1 (2021): 83. http://dx.doi.org/10.3390/coatings11010083.

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Superhydrophobic epoxy nanocomposites coatings with superior mechanical and adhesion strength are targeted to increase epoxy coating performance and to protect steel corrosion in aggressive environment. The present work prepared hydrophobic organic modified inorganic nanoparticles (NPs) based on magnetite, titanium dioxide and silver capped with epoxide oleic, linoleic and linolenic fatty acids. Their chemical structures, thermal stability, crystalline lattice structure, morphology and particles sizes distribution were determined using different tools. The curing exothermic reactions and therm

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32

Khan, Meraj, Cecil Pace-Asciak, Jassim Al-Hassan, et al. "Furanoid F-Acid F6 Uniquely Induces NETosis Compared to C16 and C18 Fatty Acids in Human Neutrophils." Biomolecules 8, no. 4 (2018): 144. http://dx.doi.org/10.3390/biom8040144.

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Various biomolecules induce neutrophil extracellular trap (NET) formation or NETosis. However, the effect of fatty acids on NETosis has not been clearly established. In this study, we focused on the NETosis-inducing ability of several lipid molecules. We extracted the lipid molecules present in Arabian Gulf catfish (Arius bilineatus, Val) skin gel, which has multiple therapeutic activities. Gas chromatography–mass spectrometry (GC-MS) analysis of the lipid fraction-3 from the gel with NETosis-inducing activity contained fatty acids including a furanoid F-acid (F6; 12,15-epoxy-13,14-dimethyleic

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33

FUKUSHIMA, A., M. HAYAKAWA, S. SUGIYAMA., et al. "Cardiovascular effects of leukotoxin (9,10-epoxy-12-octadecenoate) and free fatty acids in dogs." Cardiovascular Research 22, no. 3 (1988): 213–18. http://dx.doi.org/10.1093/cvr/22.3.213.

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34

Newman, John W., and Bruce D. Hammock. "Optimized thiol derivatizing reagent for the mass spectral analysis of disubstituted epoxy fatty acids." Journal of Chromatography A 925, no. 1-2 (2001): 223–40. http://dx.doi.org/10.1016/s0021-9673(01)00998-0.

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35

Mubiru, Edward, Liesbeth Jacxsens, Antonios Papastergiadis, et al. "Exposure assessment of epoxy fatty acids through consumption of specific foods available in Belgium." Food Additives & Contaminants: Part A 34, no. 6 (2017): 1000–1011. http://dx.doi.org/10.1080/19440049.2017.1310399.

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36

Kodani, Sean D., and Christophe Morisseau. "Role of epoxy-fatty acids and epoxide hydrolases in the pathology of neuro-inflammation." Biochimie 159 (April 2019): 59–65. http://dx.doi.org/10.1016/j.biochi.2019.01.020.

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37

Khor, Yih Phing, Khai Shin Hew, Faridah Abas, et al. "Oxidation and Polymerization of Triacylglycerols: In-Depth Investigations towards the Impact of Heating Profiles." Foods 8, no. 10 (2019): 475. http://dx.doi.org/10.3390/foods8100475.

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The stability of refined, bleached, and deodorized palm olein (RBDPO) was studied under controlled heating conditions. RBDPO was heated continuously for 24 h at 160, 170, and 180 °C, with oil sampled at four hour intervals. Thermo-oxidative alterations were measured through various parameters, such as monomeric oxidized triacylglycerols (oxTAG), total polar compounds (TPC), polymerized triacylglycerols (PTG), oxidative stability, and fatty acid composition. After 24 h of heating, the TPC and triacylglycerol oligomers showed a linear increase with heating time at all heating temperatures. At th

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38

Jonnalagadda, Deepa, Debin Wan, Jerold Chun, Bruce D. Hammock, and Yasuyuki Kihara. "A Soluble Epoxide Hydrolase Inhibitor, 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, Ameliorates Experimental Autoimmune Encephalomyelitis." International Journal of Molecular Sciences 22, no. 9 (2021): 4650. http://dx.doi.org/10.3390/ijms22094650.

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Polyunsaturated fatty acids (PUFAs) are essential FAs for human health. Cytochrome P450 oxygenates PUFAs to produce anti-inflammatory and pain-resolving epoxy fatty acids (EpFAs) and other oxylipins whose epoxide ring is opened by the soluble epoxide hydrolase (sEH/Ephx2), resulting in the formation of toxic and pro-inflammatory vicinal diols (dihydroxy-FAs). Pharmacological inhibition of sEH is a promising strategy for the treatment of pain, inflammation, cardiovascular diseases, and other conditions. We tested the efficacy of a potent, selective sEH inhibitor, 1-trifluoromethoxyphenyl-3-(1-p

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39

AGARWAL, R., A. RAUF, M. KHAN, J. MUSTAFA, and M. AHMAD. "ChemInform Abstract: Organoselenium-Mediated Cyclization of Hydroxyolefinic Fatty Acids and m-CPBA Oxidation of Selenium-Containing 1,4-Epoxy Acids." ChemInform 22, no. 45 (2010): no. http://dx.doi.org/10.1002/chin.199145235.

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40

Pinot, F., M. Skrabs, V. Compagnon та ін. "ω-Hydroxylation of epoxy- and hydroxy-fatty acids by CYP94AI: possible involvement in plant defence". Biochemical Society Transactions 28, № 6 (2000): 867–70. http://dx.doi.org/10.1042/bst0280867.

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The C18 fatty acid derivatives 9,10-epoxystearic acid and 9,10-dihydroxystearic acid were hydroxylated on the terminal methyl by microsomes of yeast expressing CYP94A1 cloned from Vicia sativa. The reactions did not occur in incubations of microsomes from yeast transformed with a void plasmid or in the absence of NADPH. After incubation of a synthetic racemic mixture of 9,10-epoxystearic acid, the chirality of the residual epoxide was shifted to 66:34 in favour of the 9S,10R enantiomer. Both the 9S, 10R and 9R, 10S enantiomers were incubated separately. We determined respective Km and Vmax val

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41

Thomæus, Stefan, Anders S. Carlsson, and Sten Stymne. "Distribution of fatty acids in polar and neutral lipids during seed development in Arabidopsis thaliana genetically engineered to produce acetylenic, epoxy and hydroxy fatty acids." Plant Science 161, no. 5 (2001): 997–1003. http://dx.doi.org/10.1016/s0168-9452(01)00500-3.

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42

Yamane, Mototeru, Akihisa Abe, and Sayoko Yamane. "High-performance liquid chromatography—thermospray mass spectrometry of epoxy polyunsaturated fatty acids and epoxyhydroxy polyunsaturated fatty acids from an incubation mixture of rat tissue homogenate." Journal of Chromatography B: Biomedical Sciences and Applications 652, no. 2 (1994): 123–36. http://dx.doi.org/10.1016/0378-4347(93)e0394-6.

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43

Samuelsson, Johan, Per-Erik Sundell, and Mats Johansson. "Synthesis and polymerization of a radiation curable hyperbranched resin based on epoxy functional fatty acids." Progress in Organic Coatings 50, no. 3 (2004): 193–98. http://dx.doi.org/10.1016/j.porgcoat.2004.02.005.

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44

Greene, Jessica F., John W. Newman, Kristin C. Williamson, and Bruce D. Hammock. "Toxicity of Epoxy Fatty Acids and Related Compounds to Cells Expressing Human Soluble Epoxide Hydrolase." Chemical Research in Toxicology 13, no. 4 (2000): 217–26. http://dx.doi.org/10.1021/tx990162c.

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45

MersiSuriani, Sinaga, Tampubolon HildeRosa, and and Ermawati. "Production of epoxy compounds from unsaturated fatty acids derived from crystallization of used cooking oil." IOP Conference Series: Earth and Environmental Science 205 (December 7, 2018): 012046. http://dx.doi.org/10.1088/1755-1315/205/1/012046.

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46

Mubiru, Edward, Kshitij Shrestha, Antonios Papastergiadis, and Bruno De Meulenaer. "Improved gas chromatography-flame ionization detector analytical method for the analysis of epoxy fatty acids." Journal of Chromatography A 1318 (November 2013): 217–25. http://dx.doi.org/10.1016/j.chroma.2013.10.025.

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47

Huang, Kun, Xuetong Fan, Richard Ashby, and Helen Ngo. "Structure-activity relationship of antibacterial bio-based epoxy polymers made from phenolic branched fatty acids." Progress in Organic Coatings 155 (June 2021): 106228. http://dx.doi.org/10.1016/j.porgcoat.2021.106228.

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48

Hu, Fengshuo, Santosh Kumar Yadav, John J. La Scala, James Throckmorton, and Giuseppe R. Palmese. "Epoxidized soybean oil modified using fatty acids as tougheners for thermosetting epoxy resins: Part 1." Journal of Applied Polymer Science 138, no. 24 (2021): 50570. http://dx.doi.org/10.1002/app.50570.

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49

Hosokawa, Masashi, Ching T. Hou та David Weisleder. "Production of Novel Tetrahydroxyfuranyl Fatty Acids from α-Linolenic Acid by Clavibacter sp. Strain ALA2". Applied and Environmental Microbiology 69, № 7 (2003): 3868–73. http://dx.doi.org/10.1128/aem.69.7.3868-3873.2003.

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ABSTRACT Previously, it was reported that a newly isolated microbial culture, Clavibacter sp. strain ALA2, produced trihydroxy unsaturated fatty acids, diepxoy bicyclic fatty acids, and tetrahydroxyfuranyl fatty acids (THFAs) from linoleic acid (C. T. Hou, J. Am. Oil Chem. Soc. 73:1359-1362, 1996; C. T. Hou and R. J. Forman III, J. Ind. Microbiol. Biotechnol. 24:275-276, 2000; C. T. Hou, H. Gardner, and W. Brown, J. Am. Oil Chem. Soc. 75:1483-1487, 1998; C. T. Hou, H. W. Gardner, and W. Brown, J. Am. Oil Chem. Soc. 78:1167-1169, 2001). In this study, we found that Clavibacter sp. strain ALA2 p

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50

Oger, Camille, Claire Cuyamendous, Aurélien de la Torre, et al. "History of Chemical Routes towards Cyclic Non-Enzymatic Oxygenated Metabolites of Polyunsaturated Fatty Acids." Synthesis 50, no. 17 (2018): 3257–80. http://dx.doi.org/10.1055/s-0036-1589540.

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Abstract:

Enzymatically formed oxygenated metabolites of polyunsaturated fatty acids (PUFA) are of great interest for the scientific community being mediators and biomarkers in the physiological and pathological regulation of many key biological processes. More recently; metabolites of PUFA formed through a non-enzymatic free radical pathway have gained interest in diseases linked with oxidative stress. Thus, synthetic strategies leading to the total synthesis of such metabolites are an essential field of research, and this review will cover a structural presentation, will discuss their biological inter

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