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Journal articles on the topic 'Eps Eri'

Author: Grafiati

Published: 4 June 2021

Last updated: 13 February 2022

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1

Joo, Jin Chul, Saeromi Lee, Chang Hyuk Ahn, Inju Lee, Zihan Liu, and Jae-Roh Park. "Development of Titanium Dioxide (TiO2)-immobilized Buoyant Photocatalyst Balls Using Expanded Polystyrene (EPS)." Ecology and Resilient Infrastructure 3, no. 4 (December 31, 2016): 215–20. http://dx.doi.org/10.17820/eri.2016.3.4.215.

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2

Pathak, P., D. J. M. Petit dit de la Roche, M. Kasper, M. Sterzik, O. Absil, A. Boehle, F. Feng, et al. "High-contrast imaging at ten microns: A search for exoplanets around Eps Indi A, Eps Eri, Tau Ceti, Sirius A, and Sirius B." Astronomy & Astrophysics 652 (August 2021): A121. http://dx.doi.org/10.1051/0004-6361/202140529.

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Context. The direct imaging of rocky exoplanets is one of the major science goals of upcoming large telescopes. The contrast requirement for imaging such planets is challenging. However, the mid-IR (infrared) regime provides the optimum contrast to directly detect the thermal signatures of exoplanets in our solar neighbourhood. Aims. We aim to exploit novel fast-chopping techniques newly developed for astronomy with the aid of adaptive optics to look for thermal signatures of exoplanets around bright stars in the solar neighbourhood. Methods. We used the upgraded Very Large Telescope Imager and Spectrometer for the mid-InfraRed (VISIR) instrument with high-contrast imaging capability optimised for observations at 10 μm to look for exoplanets around five nearby (d < 4 pc) stars. The instrument provides an improved signal-to-noise ratio (S/N) by a factor of ~4 in the N-band compared to standard VISIR for a given S/N and time. Results. In this work, we achieve a detection sensitivity of sub-mJy, which is sufficient to detect a few Jupiter mass planets in nearby systems. Although no detections are made, we achieve most sensitive limits within <2″ for all the observed targets compared to previous campaigns. For ϵ Indi A and ϵ Eri, we achieve detection limits very close to the giant planets discovered by RV, with the limits on ϵ Indi A being the most sensitive to date. Our non-detection therefore supports an older age for ϵ Indi A. The results presented here are promising for high-contrast imaging and exoplanet detections in the mid-IR regime.

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Prel, Jean-Baptist du, and Daniela Borchart. "O8D.5 Physical activity as a moderator of effort-reward imbalance over time – results of the german lida-cohort study." Occupational and Environmental Medicine 76, Suppl 1 (April 2019): A76.1—A76. http://dx.doi.org/10.1136/oem-2019-epi.204.

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BackgroundWork-related stress is widespread in modern societies and an important risk factor for common health impairments. The model of effort-reward imbalance (=ERI), one of the best-investigated occupational stress models, is associated with musculoskeletal and coronary heart diseases as well as depressive disorders. A common assumption is that physical activity (PA) antagonizes the harmful effects of distress on health. Yet, the evidence of the effect of PA on work-related stress, especially on ERI, is limited so far. The aim of this investigation was to analyze the effect of PA on ERI over time.MethodsWork-related stress was measured by ERI and physical activity by a single question asking for the weekly frequency of physical activity leading to sweating or getting out of breath over two study waves (t1, t2). Multiple linear regression analysis adjusting for sociodemographic factors (age, sex, education) was performed including interaction testing.ResultsWork-related stress at t1 was a significant predictor for work-related stress at t2. Physical activity at t2 - itself not significantly associated with work-related stress - had a significant moderating effect on work-related stress over two study waves. The higher the frequency of PA was, the lower the stress level at t2 in comparison to t1. This interaction of physical activity with ERI was also observable after adjustment for sociodemographic factors.DiscussionWe found a moderating effect of physical activity on ERI over time in agreement with former studies using other measures of work-related stress. A dose-response relationship of physical activity and ERI over two study waves was observable in our study. Regarding the detrimental effect of chronical stress on health, PA might be beneficial by mitigating the health hazards of ERI and their long-term consequences (e.g., loss of work force). Longitudinal studies over more than two waves have to prove our findings.

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4

Tomisato, k., T. Tsuchihashi, T. Maki, and T. Suzuki. "326 Evaluation of Echo Planar Fluid-Attenuated Inversion Recovery Sequence." Japanese Journal of Radiological Technology 53, no. 8 (1997): 1198. http://dx.doi.org/10.6009/jjrt.kj00001356169.

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5

Jung, Se-Gyo, Hun-Soo Jeon, Gang-Seok Lee, Seon-Min Bae, Wi-Il Yun, Kyoung-Hwa Kim, Sam-Nyung Yi, et al. "The properties of AlGaN epi layer grown by HVPE." Journal of the Korean Crystal Growth and Crystal Technology 22, no. 1 (February 29, 2012): 11–14. http://dx.doi.org/10.6111/jkcgct.2012.22.1.011.

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6

Ewusi, A., and J. Seidu. "Efficacy of Geophysical Techniques for Groundwater Exploration in the Volta Basin, Northern Region of Ghana." Ghana Mining Journal 20, no. 1 (July 7, 2020): 11–19. http://dx.doi.org/10.4314/gm.v20i1.2.

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Abstract Groundwater, traditionally extracted from hand-dug wells and boreholes is the main drinking water source in the Northern Region of Ghana. Many boreholes have been constructed in the region to increase accessibility to potable water mainly as part of rural water supply projects where borehole siting has to be relatively cheaper. These projects have resulted in low success rates of borehole drilling because of the application of inefficient and simple geophysical techniques supposed to be cheaper. Field surveys were conducted with the Electrical Resistivity Imaging (ERI) technique, Electrokinetic System (EKS) sounding technique and Radon (222Rn) technique with the objectives of determining the best geophysical methods for borehole siting and its efficiency in the Volta Basin (VB) in the Northern Region of Ghana. The surveys were conducted at stations of existing dry and positive boreholes. Results show that the three geophysical techniques are efficient to identify groundwater accumulation zones. The ERI, EKS and 222Rn are efficient to identify discontinuities, calculate hydraulic conductivity of discontinuities and identify areas of water circulation respectively. It is recommended that the ERI be used to obtain discontinuities and weak zones for drilling on rural water supply projects in the VB. The EKS and 222Rn should be conducted to evaluate these features when high yield boreholes are required. Keywords: Geophysical Techniques, Volta Basin, Borehole Drilling, Success Rates

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7

Matsuda, Tsuyoshi, Hiroyuki Sashie, and Hiroyuki Komuro. "458 Intravoxel incoherent motion (IVIM)imaging using epi method." Japanese Journal of Radiological Technology 53, no. 8 (1997): 1327. http://dx.doi.org/10.6009/jjrt.kj00001356299.

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8

Kawashima, Yukio, Kouji Shimada, Kouji Wada, Yoshikazu Shibata, and Toshio Matoba. "T2^* Dynamic MRI using EPI Sequence." Japanese Journal of Radiological Technology 52, no. 9 (1996): 1187. http://dx.doi.org/10.6009/jjrt.kj00001354929.

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9

Matsuda, tsuyoshi, hiroyuki Sashie, and hiroyuki Komuro. "Measurement of T1 value using EPI sequence." Japanese Journal of Radiological Technology 53, no. 1 (1997): 48. http://dx.doi.org/10.6009/jjrt.kj00001355043.

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10

Zennadi, Rahima, Chloe Chien, Milena Batchvarova, and Marilyn J. Telen. "Interaction of Activated Sickle Red Cell LW with Leukocytes Induces Leukocyte Adhesion to Endothelium Via CD44-E-Selectin." Blood 108, no. 11 (November 16, 2006): 1228. http://dx.doi.org/10.1182/blood.v108.11.1228.1228.

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Abstract Clinical observations have suggested a role for leukocytes in the pathophysiology of sickle cell disease (SCD). We have previously shown that epinephrine (epi), a stress hormone, activates LW-mediated sickle red cell (SS RBC) adhesion to non-activated endothelial cells (ECs). LW also recognizes leukocyte integrins. Moreover, SS RBCs can activate ECs. Therefore, we hypothesized that interaction of epi-activated LW on SS RBCs with leukocytes may also induce activation of leukocytes and stimulate their adhesion to ECs. To evaluate our hypothesis, SS RBCs were sham-treated or treated with 20 nM epi for 1 min, and after three washes, were incubated for 30 min with normal mononuclear leukocytes at 37°C. SS RBCs in leukocyte-RBC mixtures were lysed before measurement of leukocyte adhesion to non-activated ECs. Leukocytes not pre-incubated with SS RBCs and leukocytes treated with RBC lysis buffer alone did not adhere to ECs at a shear stress of 1 dyne/cm2. Incubation of sham-treated SS RBCs or sham- or epi-treated normal RBCs with leukocytes induced a non-significant adherence of 10±3%, 0% and 2% of the leukocyte population, respectively. Epi-treated SS RBCs, however, induced adhesion of 42±4.8% of leukocytes to ECs (p < 0.001). When sham- or epi-treated SS RBCs in RBC-leukocyte mixtures were not lysed, leukocyte adhesion to ECs did not further increase when compared to adhesion of leukocytes washed free of lysed sham-treated or epi-treated SS RBCs. The possible effect of residual epi on leukocytes was also tested. Exposure of leukocytes to the supernatant of the last wash of SS RBC treatment with epi had no effect on leukocyte adhesion to ECs, compared to adhesion of non-treated leukocytes to ECs. We next determined whether activated SS RBCs interact with leukocytes via the RBC LW glycoprotein. Pre-incubation of SS RBCs with antibody to LW (25 μg/ml) reduced adhesion of leukocytes induced by epi-treated SS RBCs by 78±7.9 % (p < 0.001), while pre-incubation of SS RBCs with antibody to the CD47 thrombospondin receptor (25 μg/ml) failed to inhibit the ability of epi-treated SS RBCs to stimulate leukocyte adhesion to ECs. We also identified the molecule on leukocytes mediating adhesion to ECs and its counterreceptor on ECs. Antibody to the CD44 adhesion receptor (50 μg/ml) on leukocytes blocked adhesion to ECs of leukocytes activated by epi-treated SS RBCs by 71±6.35% (p < 0.05), while antibody to CD47 failed to inhibit adhesion of activated leukocytes to ECs. Similarly, addition of recombinant soluble (rs) CD44 protein (50 μg/ml) to ECs also blocked adhesion of activated leukocytes to ECs by 74±5.8 % (p < 0.01). In contrast, incubation of rsLW (50 μg/ml) with ECs failed to inhibit adhesion of activated leukocytes. To define the endothelial counterreceptor for CD44, we incubated ECs with antibodies to adhesion molecules αVβ3 integrin, fibronectin, thrombospondin, CD44, E-selectin or P-selectin before adhesion assays. Only antibody to endothelial E-selectin completely blocked adhesion of activated leukocytes to ECs. Flow cytometric analysis showed that 36% of cultured ECs highly expressed E-selectin. These data suggest that leukocyte CD44 can be activated by cell-cell interactions mediated by RBC LW to stimulate adhesion of leukocytes to endothelial E-selectin. These studies thus provide a previously unsuspected mechanism whereby activated SS RBCs may play a role as potent stimulatory cells capable of activating leukocyte adhesion to endothelium in SCD.

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11

Kim, Inhan, Minchan Kim, and Jungsik Choi. "Improvement of Open BIM-based Building Permission Process Using EPI(Energy Performance Index)." Korean Journal of Construction Engineering and Management 16, no. 6 (November 30, 2015): 124–35. http://dx.doi.org/10.6106/kjcem.2015.16.6.124.

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12

Yun, Hyerngdu, Jinyoung Park, Taebong Choi, Intae Choi, Taihwan Noh, Bongho Han, and Myungjin Kim. "A Review on Applicability of Sustainable City Index - Focusing on GCI, EPI and CBI -." Journal of Environmental Impact Assessment 24, no. 6 (December 31, 2015): 593–606. http://dx.doi.org/10.14249/eia.2015.24.6.593.

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13

Elliott, Joanne, Michelle B. Hookham, and James A. Johnston. "The suppressors of cytokine signalling E3 ligases behave as tumour suppressors." Biochemical Society Transactions 36, no. 3 (May 21, 2008): 464–68. http://dx.doi.org/10.1042/bst0360464.

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Many studies have suggested that E3 ubiquitin ligases can behave as either oncogenes or tumour suppressor genes and, recently, it has become clear that the SOCS (suppressor of cytokine signalling) E3 ligases fit this mould. While most cancer-associated E3s regulate the cell cycle or DNA repair, the SOCS proteins inhibit growth factor responses by degrading signalling intermediates such as JAKs (Janus kinases) via the SOCS-box-associated ECS (Elongin–Cullin–SOCS) E3 ligase. Clinical studies have found that (epi)genetic (mutation or methylation) phenomena can occur in many solid tumours and a growing number of clinical findings reveal post-translational modifications that disrupt SOCS function in haematological malignancy. In the present review, we provide a summary of the functions of the SOCS E3s and propose the potential use of members of this family as diagnostic markers and therapeutic targets in cancer.

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14

DeMartini, Julie K., Douglas J. Casa, Luke N. Belval, Arthur Crago, Rob J. Davis, John J. Jardine, and Rebecca L. Stearns. "Environmental Conditions and the Occurrence of Exertional Heat Illnesses and Exertional Heat Stroke at the Falmouth Road Race." Journal of Athletic Training 49, no. 4 (August 1, 2014): 478–85. http://dx.doi.org/10.4085/1062-6050-49.3.26.

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Context: The Falmouth Road Race is unique because of the environmental conditions and relatively short distance, which allow runners to maintain a high intensity for the duration of the event. Therefore, the occurrence of exertional heat illnesses (EHIs), especially exertional heat stroke (EHS), is 10 times higher than in other races. Objective: To summarize the occurrence and relationship of EHI and environmental conditions at the Falmouth Road Race. Design: Descriptive epidemiologic study. Setting: An 11.3-km (7-mile) road race in Falmouth, Massachusetts. Patients or Other Participants: Runners who sustained an EHI while participating in the Falmouth Road Race. Main Outcome Measure(s): We obtained 18 years of medical records and environmental conditions from the Falmouth Road Race and documented the incidence of EHI, specifically EHS, as related to ambient temperature (Tamb), relative humidity, and heat index (HI). Results: Average Tamb, relative humidity, and HI were 23.3 ± 2.5°C, 70 ± 16%, and 24 ± 3.5°C, respectively. Of the 393 total EHI cases observed, EHS accounted for 274 (70%). An average of 15.2 ± 13.0 EHS cases occurred each year; the incidence was 2.13 ± 1.62 cases per 1000 runners. Regression analysis revealed a relationship between the occurrence of both EHI and EHS and Tamb (R2 = 0.71, P = .001, and R2 = 0.65, P = .001, respectively) and HI (R2 = 0.76, P < .001, and R2 = 0.74, P < .001, respectively). Occurrences of EHS (24.2 ± 15.5 cases versus 9.3 ± 4.3 cases) and EHI (32.3 ± 16.3 versus 13.0 ± 4.9 cases) were higher when Tamb and HI were high compared with when Tamb and HI were low. Conclusions: Because of the environmental conditions and race duration, the Falmouth Road Race provides a unique setting for a high incidence of EHS. A clear relationship exists between environmental stress, especially as measured by Tamb and HI, and the occurrence of EHS or other EHI. Proper prevention and treatment strategies should be used during periods of high environmental temperatures as the likelihood of runners experiencing EHS is exacerbated in these harsh conditions.

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15

Schermann, Haggai, Shir Hazut-Krauthammer, Yael Weksler, Sagi Spitzer, Yoram Epstein, Gary Kalmanovich, and Ran Yanovich. "When Should a Heat-Tolerance Test Be Scheduled After Clinical Recovery From an Exertional Heat Illness?" Journal of Athletic Training 55, no. 3 (March 1, 2020): 289–94. http://dx.doi.org/10.4085/1062-6050-478-18.

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Objective Researchers have produced a hypothesis of transient heat intolerance (HI) after exertional heat stroke (EHS). Based on this hypothesis, heat-tolerance testing (HTT) has been postponed until weeks 6 to 8 after EHS and other types of exertional heat illness (EHI). We compared the HTT results of participants after either EHS or other EHI who were tested earlier (≤6-week group) versus those who were tested later (>6-week group) to verify the hypothesis. Design Cohort study. Setting Data obtained from records of military athletes who experienced EHS or EHI. Patients or Other Participants All participants who underwent HTT after EHI or EHS experienced between 2014 and 2018 and for whom complete data regarding the severity of the event (rectal temperature, neurologic symptoms, and laboratory results) and HTT results were available were included. Participants with suspected EHS and those with other EHIs were evaluated separately. Main Outcome Measure(s) The percentages of participants with HI and mean probability of heat tolerance were compared between those tested within 6 weeks of the event and those tested later. Results A total of 186 participants were included in this study (EHS: 12 in the <6-week group, 9 in the >6-week group; EHI: 94 in the <6-week group, 71 in the >6-week group). In the EHS group, the percentages with HI (33% versus 44%, P = .67) and mean probability of heat tolerance (0.82 versus 0.82, P = .98) did not differ. In the EHI group, participants who were tested after 6 weeks had a greater chance of being diagnosed with HI (38% versus 21.3%, P < .02) Conclusions The HTT results were similar between participants with EHS who were tested early (<6 weeks) and those tested late (>6 weeks). Further investigation of heat-tolerance changes in larger cohorts of patients after EHS is required to verify the theory of transient HI.

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16

Lancíková, Veronika, and Jana Žiarovská. "Radioactive contamination in Chernobyl and (epi)genetic stability of plants – A review." Journal of Central European Agriculture 21, no. 3 (2020): 657–66. http://dx.doi.org/10.5513/jcea01/21.3.2709.

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17

Shimada, Kouji, Yukio Kawashima, Kouji Wada, Yoshikazu Shibata, and Toshio Matoba. "Functional MRI using Echo planar Imaging." Japanese Journal of Radiological Technology 52, no. 9 (1996): 1179. http://dx.doi.org/10.6009/jjrt.kj00001354921.

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18

Siess, L. "The formation of long-period eccentric binaries with a helium white dwarf companion." EAS Publications Series 82 (2019): 107–18. http://dx.doi.org/10.1051/eas/1982011.

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The recent discovery of long-period eccentric binaries hosting a He-white dwarf has been a challenge for binary-star modelling. Based on accurate determinations of the stellar and orbital parameters for IP Eri, a K0 + He-WD system, we propose an evolutionary path that is able to explain the observational properties of this system and, in particular, to account for its high eccentricity (0.25). Our scenario invokes an enhanced-wind mass loss on the first red giant branch in order to avoid mass transfer by Roche-lobe overflow, where tides systematically circularize the orbit.

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19

Polgár, András, and József Pájer. "Enhancement of the Corporate Environmental Performance." Acta Silvatica et Lignaria Hungarica 10, no. 1 (September 1, 2014): 49–64. http://dx.doi.org/10.2478/aslh-2014-0004.

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Abstract In the course of the implementation of the environmental management system (EMS), during the planning phase it is of high priority to explore, select and analyse the relevant environmental aspects and impacts. This is the precondition to enhance the real environmental performance (EP). The applied processes are often specific, formal and influenced by the self-interest of a company. The purpose of our work was the uniformly interpretable evaluation of the varied processes, and the creation of an EMS enhancement model through which the physical EP can be improved. The quantitative empirical research (2010-2011) has been conducted by using questionnaires in 114 domestic and multinational companies applying an EMS according to the international standard ISO 14001. In the created database, we have determined the variables which are relevant and adjustable in the process, through a descriptive and multivariable statistical survey. On the basis of the identified performance dimensions, corporate performance indices have been created: the environmental motivation (MOT), environmental performance (EPI), environmental impact evaluation (EIE) and environmental management (EMI) as well as the aggregative index (AGG). With their help, the evaluation of the surveyed corporate performance can be executed uniformly, in a quantifiable way, without any intervention in the corporate processes. Along the outliers of EMS optimization variables, we have identified development points. Their impact was assessed by sensitivity analysis of the indices. The described method offers a model for EMS development, based on self-evaluation.

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20

Yamada, Masami. "The Basic Study of Heart Perfusion Imaging by EPI." Japanese Journal of Radiological Technology 53, no. 7 (1997): 839. http://dx.doi.org/10.6009/jjrt.kj00001355855.

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21

Reale, Elisa, Daniela Taverna, Laura Cantini, Loredana Martignetti, Matteo Osella, Cristiano De Pittà, Federico Virga, Francesca Orso, and Michele Caselle. "Investigating the epi-miRNome: identification of epi-miRNAs using transfection experiments." Epigenomics 11, no. 14 (November 2019): 1581–99. http://dx.doi.org/10.2217/epi-2019-0050.

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Aim: Growing evidence shows a strong interplay between post-transcriptional regulation, mediated by miRNAs (miRs) and epigenetic regulation. Nevertheless, the number of experimentally validated miRs (called epi-miRs) involved in these regulatory circuitries is still very small. Material & methods: We propose a pipeline to prioritize candidate epi-miRs and to identify potential epigenetic interactors of any given miR starting from miR transfection experiment datasets. Results & conclusion: We identified 34 candidate epi-miRs: 19 of them are known epi-miRs, while 15 are new. Moreover, using an in-house generated gene expression dataset, we experimentally proved that a component of the polycomb-repressive complex 2, the histone methyltransferase enhancer of zeste homolog 2 (EZH2), interacts with miR-214, a well-known prometastatic miR in melanoma and breast cancer, highlighting a miR-214-EZH2 regulatory axis potentially relevant in tumor progression.

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22

Raynaud, Laure, Benoît Touzé, and Philippe Arbogast. "Detection of Severe Weather Events in a High-Resolution Ensemble Prediction System Using the Extreme Forecast Index (EFI) and Shift of Tails (SOT)." Weather and Forecasting 33, no. 4 (June 15, 2018): 901–8. http://dx.doi.org/10.1175/waf-d-17-0183.1.

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Abstract The extreme forecast index (EFI) and shift of tails (SOT) are commonly used to compare an ensemble forecast to a reference model climatology, in order to measure the severity of the current weather forecast. In this study, the feasibility and the relevance of EFI and SOT computations are examined within the convection-permitting Application of Research to Operations at Mesoscale (AROME-France) ensemble prediction system (EPS). First, different climate configurations are proposed and discussed, in order to overcome the small size of the ensemble and the short climate sampling length. Subjective and objective evaluations of EFI and SOT for wind gusts and precipitation forecasts are then presented. It is shown that these indices can provide relevant early warnings and, based on a trade-off between hits and false alarms, optimal EFI thresholds can be determined for decision-making.

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23

Chowdhury, Tonmoy. "Nexus between Foreign Direct Investment Inflow and EPI Score in Brazil." International Journal of Trade, Economics and Finance 12, no. 1 (February 2021): 16–20. http://dx.doi.org/10.18178/ijtef.2021.12.1.687.

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Before 1990, foreign investors could not extensively invest in Brazil because of its stringent and conservative trade policy. However, in 1990 Brazil took a remarkable shift in its trade policy from its previous trends by taking a liberal stance in terms of FDI inflow. The liberal trade policy that Brazil took in 1990 remove all the trade barriers that previously hindered the free flow of FDI in Brazil, the sign of which had been reflected in the steady and gradual incremental FDI inflow in the country after that. This New opening of trade atmosphere had brought with it two very different repercussions. In one hand, it accelerated the economic growth by bringing in investment in the needed sectors; on the other hand this acceleration spurred industrial activities that are accompanied by air and water pollution and deforestation as a byproduct. Since then, environmental health and ecosystem of Brazil have been facing tremendous threat owing to these pollution problems which may indirectly distress the EPI score of Brazil. Keeping these issues in mind, the present study investigates the relationship between FDI inflow and EPI score in Brazil. With the help of descriptive statistical tools as well as Pearson correlation test, this study finds the negative relationship between FDI inflow and EPI score in Brazil.

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Koga, Shouichi, Yasuhiko Nakamura, Hiroyuki Nishimura, Fumiyoshi Matsuo, and Futoshi Mihara. "The basic study of brain perfusion imaging by EPI." Japanese Journal of Radiological Technology 52, no. 9 (1996): 1190. http://dx.doi.org/10.6009/jjrt.kj00001354932.

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25

Kim, Jin-Seo, and Hyungtak Seo. "Comparison on the Physical & Chemical Characteristics in Surface of Polished Wafer and Epi-Layer Wafer." Korean Journal of Materials Research 24, no. 12 (December 27, 2014): 682–88. http://dx.doi.org/10.3740/mrsk.2014.24.12.682.

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Grigorieva, A. A. Grigorieva, L. V. Berzegova Berzegova, K. V. Kozhina Kozhina, and E. V. Svechnikova Svechnikova. "Epi-Oral F199 – systemic anti-age therapy and antioxidant protection: ingredients." Pharmateca 8_2021 (August 16, 2021): 67–71. http://dx.doi.org/10.18565/pharmateca.2021.8.67-71.

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27

Surdej, J., A. Chelli, P. Garcia, Th Henning, and A. Quirrenbach. "The European Interferometry Initiative (EII) within OPTICON." EAS Publications Series 25 (2007): 301–8. http://dx.doi.org/10.1051/eas:2007111.

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28

Zamfir, V., K. Tanaka, and C. Ur. "Extreme light infrastructure nuclear physics (ELI-NP)." Europhysics News 50, no. 2 (March 2019): 23–25. http://dx.doi.org/10.1051/epn/2019204.

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ELI - Extreme Light Infrastructure, a project to build an international research infrastructure “dedicated to the investigation and applications of laser matter interaction at the highest intensity level” is one of the 35 projects in the first Roadmap, in 2006, of the European Strategy Forum on Research Infrastructures (ESFRI) [1]. “ELI will comprise three branches: ultra high field science that will explore laser matter interaction up to the nonlinear QED limit including the investigation of pair creation and vacuum structure; attosecond laser science designed to conduct temporal investigation at the attosecond scale of electron dynamics in atoms, molecules, plasmas, and solids; lastly, the highenergy beam facility devoted to the development of dedicated beam lines of ultra short pulses of high energy radiation and particles up to 100GeV for users.”

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Fukumoto, Kohei, Hideyuki Konishi, Koichi Soga, Ki-ichiro Miyawaki, Hitoshi Okano, Masahito Minami, Naoki Wakabayashi, et al. "Successful Endoscopic Injection Sclerotherapy of High-Risk Gastroesophageal Varices in a Cirrhotic Patient with Hemophilia A." Gastroenterology Research and Practice 2010 (2010): 1–5. http://dx.doi.org/10.1155/2010/518260.

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A 68-year-old man with hemophilia A and liver cirrhosis caused by hepatitis C virus was referred to our hospital to receive prophylactic endoscopic treatment for gastroesophageal varices (GOV). He had large, tense, and winding esophageal varices (EV) with cherry red spots extending down to lesser curve, predicting the likelihood of bleeding. Esophageal endoscopic injection sclerotherapy (EIS) was performed with a total 15 mL of 5% ethanolamine oleate with iopamidol (EOI). Radiographic imaging during EIS demonstrated that 5% EOI reached the afferent vein of the varices. He was administered sufficient factor VIII concentrate before and after EIS to prevent massive bleeding from the varices. Seven days after EIS, upper gastrointestinal endoscopy (UGIE) showed that the varices were eradicated almost completely. Eighteen months after EIS, the varices continued to diminish. We report a successful case of safe and effective EIS for GOV in a high-risk cirrhotic patient with hemophilia A.

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Blanco, Flávio Favaro, Marcos Vinícius Folegatti, Hans Raj Gheyi, and Pedro Dantas Fernandes. "Emergence and growth of corn and soybean under saline stress." Scientia Agricola 64, no. 5 (October 2007): 451–59. http://dx.doi.org/10.1590/s0103-90162007000500001.

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Emergence and seedling growth may be severely affected by salinity, mainly for sensitive crops. The objective of the present study was to verify the tolerance of corn and soybean to the irrigation water salinity (ECi) during the emergence and initial development stages. Seeds of corn, hybrid 'AG-6690', and soybean, cv. 'Conquista', were sown in pots containing material from a sandy-loam soil and irrigated with water of increasing salinity levels, from 0.3 to 5.9 dS m-1, giving nine levels of ECi obtained by the addition of an equivalent proportion of sodium and calcium chloride, except for ECi = 0.3 dS m-1 (tap water). Emergence of corn was not affected by salinity but seedling development was reduced for ECi above 1.5 dS m-1. Emergence and growth of soybean were reduced by water salinity and the crop was more tolerant during the emergence (ECi = 2.7 dS m-1) than in the initial development (ECi = 1.0 dS m-1) stage. Salinity of soil solution (ECs) was linearly correlated to ECi and affected the growth of corn and soybean for ECs higher than 3 and 2 dS m-1, respectively.

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Prashanth, Jangiti Siva, and Satyanarayana V. Nandury. "A Cluster–based Approach for Minimizing Energy Consumption by Reducing Travel Time of Mobile Element in WSN." International Journal of Computers Communications & Control 14, no. 6 (November 27, 2019): 691–709. http://dx.doi.org/10.15837/ijccc.2019.6.3630.

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Envoy Node Identification (ENI) and Halting Location Identifier (HLI) algorithms have been developed to reduce the travel time of Mobile Element (ME) by determining Optimal Path(OP) in Wireless Sensor Networks. Data generated by cluster members will be aggregated at the Cluster Head (CH) identified by ENI for onward transmission to the ME and it likewise decides an ideal path for ME by interfacing all CH/Envoy Nodes (EN). In order to reduce the tour length (TL) further HLI determines finest number of Halting Locations that cover all ENs by taking transmission range of CH/ENs into consideration. Impact of ENI and HLI on energy consumption and travel time of ME have been examined through simulations.

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OGURA, AKIO, TAKAHARU HONGOH, HIROSHI INOUE, MASARU YAMAZAKI, and MITSUHARU HIGASHIDA. "Comparison of dB/dt between EPI and Spin-echo Pulse Sequences." Japanese Journal of Radiological Technology 57, no. 4 (2001): 444–48. http://dx.doi.org/10.6009/jjrt.kj00001357563.

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De Castro, Laura M., Jude C. Jonassaint, Jennifer G. Johnson, Milena Batchvarova, and Marilyn J. Telen. "Effect of Single Dose In Vivo Propranolol Therapy on In Vitro Adhesion of Human SS RBC." Blood 108, no. 11 (November 16, 2006): 1234. http://dx.doi.org/10.1182/blood.v108.11.1234.1234.

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Abstract Sickle red blood cells (SS RBC) are abnormally adhesive to both endothelial cells (ECs) and components of the extracellular matrix (ECM). Epinephrine (epi) has been shown to elevate cAMP in SS RBC and increase adhesion of SS RBC to ECs in a protein kinase A-dependent manner. In vitro and in vivo studies performed in our lab have led to the hypothesis that adrenergic stimuli such as epi may initiate or exacerbate vaso-occlusion and thus contribute to the association of vaso-occlusive events with physiologic stress. We are conducting a prospective, dose-escalation pilot clinical study to investigate whether in vivo administration of one dose of propranolol either down-regulates baseline SS RBC adhesion in vitro or prevents its upregulation by epi. In addition, this study will provide additional safety data regarding the use of propranolol in normotensive patients with sickle cell disease (SCD). Figure Figure To date, we have completed the first two dose cohorts. 11 subjects (9 SS and 1 Sβ° thalassemia; 7 females, 3 males) have participated. No severe adverse events were noted. Cohorts 1 and 2 had mean pre-propranolol blood pressure (BP) of 116 (5.9 SD)/ 60.4 (3.98 SD) and 106.8 (4.68 SD)/ 58 (3.9 SD), respectively; this difference was not statistically significant. Minimal and asymptomatic changes in BP were noted in both cohorts after drug administration, with biphasic systolic and diastolic BP nadirs at 45 and 240 minutes. No clinically significant changes in heart rate were observed. Adhesion studies were performed using a graduated height flow chamber on the day of RBC collection. RBC adhesion to ECs was studied before and after epi stimulation and was measured at sheer stresses ranging from 1 to 3 dyne/cm2. Baseline adhesion measurements were validated by comparing percent (%) adhesion assayed at 2 different times within 7 days—at screening and before propranolol dose on the study drug day. We observed no significant difference in adhesion at the 2 different time points without propranolol. Comparison of % adhesion of epi-stimulated RBC to ECs before and 1 hour after propranolol showed that propranolol given in vivo significantly inhibited both non-stimulated and epi-stimulated SS RBC adhesion (p=0.04 and p=0.001, respectively). Lastly, comparison of SS RBC adhesion at both drug doses confirmed the drug-related inhibition of adhesion (p<0.004). We conclude that propranolol administered in vivo decreases SS RBC baseline adhesion to ECs and substantially abrogates epi-stimulated adhesion to ECs, as measured in vitro. Although we have thus far studied only a small number of patients and low propranolol doses, we expect to confirm these results with the 3rd cohort, in which a higher dose of propranolol will be used. If our findings continue to show that propranolol can decrease both SS RBC baseline and epi-stimulated adhesion to ECs, study of propranolol on a larger scale would be warranted in order to ascertain its safety and efficacy as an anti-adhesive therapy in SCD.

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Komiya, Taizo, Saroshi Ogawa, and Isao Muro. "Trial of 3D Functional-MRI using Multi Shot EPI." Japanese Journal of Radiological Technology 52, no. 9 (1996): 1176. http://dx.doi.org/10.6009/jjrt.kj00001354918.

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Sutton, Stephen G., and Emma Gyuris. "Optimizing the environmental attitudes inventory." International Journal of Sustainability in Higher Education 16, no. 1 (January 5, 2015): 16–33. http://dx.doi.org/10.1108/ijshe-03-2013-0027.

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Purpose – The purpose of this study was twofold: first, to optimize the Environmental Attitudes Inventory (EAI) and second, to establish a baseline of the difference in environmental attitudes between first and final year students, taken at the start of a university’s declaration of commitment to EfS. Design/methodology/approach – The psychometrically designed EAI was used to overcome the problems and limitations of the much-used, but controversial, revised New Environmental Paradigm (NEP) Scale. The performance of the original 72-item EAI was compared with our 37-item reduced form using a population of first- and final-year university students. Findings – The reduced 37-item EAI provides a reliable and valid tool for investigating structured, multi-dimensional environmental attitudes of university students while reducing response burden and increasing response and completion rates compared with the longer versions of the EAI. Research limitations/implications – No attempt is made to link elements of the university experience with changes in attitude between first- and third-year students. The authors expect the 12-faceted EAI to provide more detailed feedback on the affective outcomes of EfS initiatives than currently used instruments. Originality/value – This research contributes to establishing the EAI as a gold standard with which to monitor students’ environmental attitudes. Although most studies aimed at understanding the impact of EfS measure attitude change over relatively short periods of time – typically using the brief NEP scale administered immediately before and after a specific semester course – the approach developed here is designed to detect attitudinal change that may be ascribed to the entire university experience between students’ first and final year.

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Park, Ji-Hye, Sang-Dong Park, Sang-Hong Lee, and Choon-Seob Tae. "A Study on the Improvement of Scoring System of Energy Performance in G-SEED through Analysis of EPI Scores and Delphi Survey Method." Journal of the architectural institute of Korea planning & design 30, no. 8 (August 30, 2014): 227–34. http://dx.doi.org/10.5659/jaik_pd.2014.30.8.227.

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Alele, Faith O., Bunmi S. Malau-Aduli, Aduli E. O. Malau-Aduli, and Melissa J. Crowe. "Epidemiology of Exertional Heat Illness in the Military: A Systematic Review of Observational Studies." International Journal of Environmental Research and Public Health 17, no. 19 (September 25, 2020): 7037. http://dx.doi.org/10.3390/ijerph17197037.

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Exertional heat illness (EHI) is an occupational hazard among military personnel. This systematic review describes the incidence, risk factors, clinical manifestations, and biomarkers of EHI in the military. Six databases from inception to 28 May 2020 were systematically reviewed using the PRISMA guidelines. Forty-one articles met the inclusion criteria and the incidence of EHI ranged from 0.2 to 10.5 per 1000 person years, while the prevalence rates ranged from 0.3% to 9.3%. Intrinsic risk factors influencing EHI were gender, physical fitness, obesity, previous history of heat illness, and motivation, while the extrinsic factors included hot environmental conditions and service unit. Evidence suggests that loss of consciousness, absence of sweating and confusion were the common clinical features of exertional heat stroke (EHS). The mean core temperature ranged from 40 to 41.6 °C, while elevated levels of creatine phosphokinase, liver enzymes, and creatinine were common biochemical markers of EHS. The findings of the review suggest a variation in the incidence of EHI among military populations possibly due to the varying definitions used. Although some risk factors of EHI were identified, more analytical studies are needed to investigate the association between EHI and other important factors such as acclimatisation and occlusive clothing.

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Muhammad, Wasif Saif, Romano Alicia, H. Smith Melissa, Patel Rachana, and Relias Valerie. "Chronic Use of Long-Acting Somatostatin Analogues (SSAs) and Exocrine Pancreatic Insufficiency (EPI) in Patients with Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs): An Under-recognized Adverse Effect." Cancer Medicine Journal 3, no. 2 (December 31, 2020): 75–84. http://dx.doi.org/10.46619/cmj.2020.3-1023.

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Background: Somatostatin Analogues (SSAs) are used to treat Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) and acromegaly. Side effects of SAAs usually include biliary disorders, gastrointestinal disorders, injection-site pain and hyperglycemia. Exocrine Pancreatic Insufficiency (EPI) is often misdiagnosed as disease progression or failure to SAAs or diagnosed after a delay in patients receiving SAAs. We present our experience with EPI developing in patients following use of SAAs. Methods: We reviewed chart and pharmacy records of 110 GEP-NETs patients who received SSAs. Data was collected including demographics, pathology, stage, dose/duration of long and short-acting SA, use of antidiarrheal, pancreatic enzyme replacement (PER), proton pump inhibitors (PPI) or H2 blockers). Laboratory data include chromogranin-A (CgA), urine 5-HIAA and quantitative fecal fat test (QFFT) or fecal elastase test (FE). EPI was defined by a FE below normal level OR by a reduction of ≥ 21.2% or steatorrhea on QFFT. Patients who were identified to develop EPI were treated with pancreatic exocrine replacement therapy (PERT). Results: Among, 110 GEP-NETs patients, 104 received LA Octreotide and 6 Somatuline Depot Injection. Of these, 23 received shortacting SSA for worsening diarrhea, 96 had intensification of antidiarrheal and 1 got telotristat ethyl. QFFT confirmed EPI in 19, 11 based on clinical symptoms, and 16 had sample error or refusal to collect specimen. CTCAE 4.0 grades of EPI were: grade 2(69%), grade 3(22%) and grade 4(9%). Median time to development of EPI was 12 months (95%CI 3 - 23). Except 1, all patients received PERT either with concomitant PPI (13) or later if no improvement with PERT (6) and 2 on H2 blockers. 37% of the patients had improvement in EPI within 4-8 weeks. Deficiency of vitamins and trace elements was found in 11 of 19 patients, who received supplementation. Conclusions: Our experience constitutes the first and the largest study addressing EPI as a rare but serious complication of chronic use of SAAs. Although SAAs are used to treat diarrhea, paradoxically they can worsen diarrhea secondary to EPI. Early recognition and diagnosis of this under-diagnosed and under-reported side effect of SAAs, such as EPI, can improve not only diarrhea and weight loss in these patients but also can reduce cost of using short-acting SAAs and antidiarrheal.

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Barbosa, André Victor, Aloysio de Mello Figueiredo Cerqueira, Leonardo Alves Rusak, Cristhiane Moura Falavina Dos Reis, Nilma Cintra Leal, Ernesto Hofer, and Deyse Christina Vallim. "Characterization of epidemic clones of Listeria monocytogenes serotype 4b isolated from humans and meat products in Brazil." Journal of Infection in Developing Countries 9, no. 09 (September 27, 2015): 962–69. http://dx.doi.org/10.3855/jidc.5639.

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Introduction: Listeria monocytogenes is an important foodborne pathogen and the 4b serotype is responsible for many cases of human listeriosis reported in Brazil. Several listeriosis outbreaks worldwide have involved a small number of well-defined clonal groups, designated as epidemic clones (ECs). Methodology: We studied 71 strains of serotype 4b, including 25 isolates from human cases of listeriosis and 46 from meat-based foods, collected in Brazil between 1977 and 2010. The presence of ECs (I and II) markers and virulence genes (inlA, inlB, ilnC, inlJ and actA) were evaluated by PCR assay. The genetic relationship of ECs-positive strains was assessed by pulsed field gel electrophoresis. Results: ECI and ECII markers were found both in human and food strains, with 19.7% positive for the ECI marker and 40.8% for ECII. Most strains (97.2%) were positive for the virulence genes that were studied. Nevertheless, the actA gene amplicons showed two distinct sizes, with all ECI positive strains exhibiting a 105bp deletion. Pulsed field gel electrophoresis (PFGE) analysis allowed the recognition of highly related strains, particularly from two outbreaks of neonatal listeriosis in São Paulo State occurred in 1992 and 1997, both ECII-positive; and two ECI strains from a human case (1982) and from bovine meat (2009). Conclusions: The presence of ECs among clinical samples and beef isolates of serotype 4b from some regions of Brazil highlights the need for rigorous control of production procedures. Furthermore, the association of ECII with two nosocomial outbreaks suggests its ability to spread in these settings.

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"Epoxy Resins and their Zinc Composites as Novel Anti-Corrosive Materials for Copper in 3% Sodium Chloride Solution: Experimental and Computational Studies." Proceedings International 2, no. 2 (September 27, 2020): 40–41. http://dx.doi.org/10.33263/proceedings22.040041.

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The evaluation the anticorrosive performance of two macromolecular aromatic epoxy resins (ERs), namely, tetra glycidyl of ethylene dianiline (TGEDA), hexaglycidyl Tris (p-Ethylene Dianiline) Phosphoric Triamide (HGEDPAT), and their polymer composite reinforced with Zinc for copper corrosion in 3% NaCl by means of computational and experimental analyses. Anticorrosive property of the standards and composites was demonstrated using experimental and computational methods. Electrochemical results showed that HGEDAPT cured with methylene dianiline (MDA) showed better protection efficiency with optimum corrosion current density (icorr) value of 2.0 µcm-2 and the polarization resistance (Rp) value of 17,00 kΩ.cm2 than that of TGEDA-MDA having icorr value of 2.4 µcm-2 and the Rp value of 15.24 kΩ.cm2. The anticorrosive effect of TGEDA-MDA and HGEDAPT-MDA was evaluated in the presence of 5% zinc (Zn). Experimental results demonstrate that the presence of 5% of zinc in TGEDA-MDA and HGEDAPT-MDA formulations significantly enhanced their protection ability. The anticorrosive effect of different formulations followed the order: ER1 (TGEDA-MDA) (potentiodynamic polarization (PDP); 90% and electrochemical impedance spectroscopy (EIS) 92%) < ER2 (HGEDAPT-MDA) (PDP; 92% and EIS 93%) < ER3 (TGEDA-MDA-5%Zn) (PDP; 96% and EIS 97%) < ER4 (HGEDAPT-MDA-5%Zn) (PDP; 97% and EIS 98.5%). Density Functional Theory (DFT) study revealed that ER1 and ER2 interact with the metallic surface using donor-acceptor interactions in which electron-rich centers acted as the most favorable sites for the interactions. Molecular dynamics (MD) simulations studies suggest that ER1 and ER2 acquire flat or horizontal orientations, and their orientations on the metallic surface are largely influenced by the presence of zinc. Different experimental and computational studies are in good agreement.

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Japanese Journal of Radiological Technology 53, no. 11 (1997): 12–14. http://dx.doi.org/10.6009/jjrt.kj00001355437.

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"Thorn EMI acquires EPS." Electronics and Power 31, no. 2 (1985): 107. http://dx.doi.org/10.1049/ep.1985.0080.

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"Evaluation of FLAIR sequence using EPI." Japanese Journal of Radiological Technology 53, no. 1 (1997): 178. http://dx.doi.org/10.6009/jjrt.kj00001355173.

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Müller, Domenique M. J., Pierre A. Robe, Hilko Ardon, Frederik Barkhof, Lorenzo Bello, Mitchel S. Berger, Wim Bouwknegt, et al. "Quantifying eloquent locations for glioblastoma surgery using resection probability maps." Journal of Neurosurgery, April 2020, 1–11. http://dx.doi.org/10.3171/2020.1.jns193049.

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OBJECTIVEDecisions in glioblastoma surgery are often guided by presumed eloquence of the tumor location. The authors introduce the “expected residual tumor volume” (eRV) and the “expected resectability index” (eRI) based on previous decisions aggregated in resection probability maps. The diagnostic accuracy of eRV and eRI to predict biopsy decisions, resectability, functional outcome, and survival was determined.METHODSConsecutive patients with first-time glioblastoma surgery in 2012–2013 were included from 12 hospitals. The eRV was calculated from the preoperative MR images of each patient using a resection probability map, and the eRI was derived from the tumor volume. As reference, Sawaya’s tumor location eloquence grades (EGs) were classified. Resectability was measured as observed extent of resection (EOR) and residual volume, and functional outcome as change in Karnofsky Performance Scale score. Receiver operating characteristic curves and multivariable logistic regression were applied.RESULTSOf 915 patients, 674 (74%) underwent a resection with a median EOR of 97%, functional improvement in 71 (8%), functional decline in 78 (9%), and median survival of 12.8 months. The eRI and eRV identified biopsies and EORs of at least 80%, 90%, or 98% better than EG. The eRV and eRI predicted observed residual volumes under 10, 5, and 1 ml better than EG. The eRV, eRI, and EG had low diagnostic accuracy for functional outcome changes. Higher eRV and lower eRI were strongly associated with shorter survival, independent of known prognostic factors.CONCLUSIONSThe eRV and eRI predict biopsy decisions, resectability, and survival better than eloquence grading and may be useful preoperative indices to support surgical decisions.

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Asatryan, H. R., G. S. Shakurov, A. G. Petrosyan, and K. L. Hovannesyan. "Wideband EPR-spectroscopy of Y3Al5O12:Er3+, (Y0.9Lu0.1)3Al5O12:Er3+ and Y3Al5O12:Fe2+ crystals." Magnetic resonance in solids 21, no. 4 (2019). http://dx.doi.org/10.26907/mrsej-19403.

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Belov, Vladimir, Alexey Shamaev, Peter Leisner, Alf Johansson, Bengt Magnhagen, and Ilja Belov. "A Simulation-based Spectral Technique for Power Quality and EMC Design of an Independent Power System." International Journal of Emerging Electric Power Systems 7, no. 1 (September 8, 2006). http://dx.doi.org/10.2202/1553-779x.1355.

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A novel simulation-based spectral technique for power quality and electromagnetic compatibility (EMC) design of an independent electrical power system (EPS) has been proposed. Power filter optimization problem has been formulated to provide full solution of the electric power quality and conducted EMI problems in the EPS. The spectral technique has been implemented within a CAD tool. An example of power quality and EMC design has been provided for an independent EPS where an AC power source generates a power, which is comparable to the consumed power, and an additional power filter is calculated for an electronic product including a switch-mode power supply. Current and voltage spectra calculations have been verified with a block-oriented simulation program Simulink. Numerical experiments revealed a number of important features of the proposed spectral technique.

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"Evaluation of scan parameters in GR-EPI." Japanese Journal of Radiological Technology 53, no. 1 (1997): 191. http://dx.doi.org/10.6009/jjrt.kj00001355186.

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Japanese Journal of Radiological Technology 57, no. 9 (2001): 1058. http://dx.doi.org/10.6009/jjrt.kj00003111221.

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"321 Clinical aplicasion of MRCP a using EPI." Japanese Journal of Radiological Technology 53, no. 8 (1997): 1193. http://dx.doi.org/10.6009/jjrt.kj00001356164.

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Dinkler, Lisa, Mark J. Taylor, Maria Råstam, Nouchine Hadjikhani, Cynthia M. Bulik, Paul Lichtenstein, Christopher Gillberg, and Sebastian Lundström. "Association of etiological factors across the extreme end and continuous variation in disordered eating in female Swedish twins." Psychological Medicine, December 17, 2019, 1–11. http://dx.doi.org/10.1017/s0033291719003672.

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Abstract Background Accumulating evidence suggests that many psychiatric disorders etiologically represent the extreme end of dimensionally distributed features rather than distinct entities. The extent to which this applies to eating disorders (EDs) is unknown. Methods We investigated if there is similar etiology in (a) the continuous distribution of the Eating Disorder Inventory-2 (EDI-2), (b) the extremes of EDI-2 score, and (c) registered ED diagnoses, in 1481 female twin pairs at age 18 years (born 1992–1999). EDI-2 scores were self-reported at age 18. ED diagnoses were identified through the Swedish National Patient Register, parent-reported treatment and/or self-reported purging behavior of a frequency and duration consistent with DSM-IV criteria. We differentiated between anorexia nervosa (AN) and other EDs. Results The heritability of the EDI-2 score was 0.65 (95% CI 0.61–0.68). The group heritabilities in DeFries–Fulker extremes analyses were consistent over different percentile-based extreme groups [0.59 (95% CI 0.37–0.81) to 0.65 (95% CI 0.55–0.75)]. Similarly, the heritabilities in liability threshold models were consistent over different levels of severity. In joint categorical-continuous models, the twin-based genetic correlation was 0.52 (95% CI 0.39–0.65) between EDI-2 score and diagnoses of other EDs, and 0.26 (95% CI 0.08–0.42) between EDI-2 score and diagnoses of AN. The non-shared environmental correlations were 0.52 (95% CI 0.32–0.70) and 0.60 (95% CI 0.38–0.79), respectively. Conclusions Our findings suggest that some EDs can partly be conceptualized as the extreme manifestation of continuously distributed ED features. AN, however, might be more distinctly genetically demarcated from ED features in the general population than other EDs.

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