Relevant bibliographies by topics / Epw

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  2. Dissertations / Theses
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  4. Book chapters
  5. Conference papers
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Academic literature on the topic 'Epw'

Author: Grafiati
Published: 11 September 2021
Last updated: 22 June 2025

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Journal articles on the topic "Epw"

1

DISTEFANO, Stefania, M. José PALMA, Manuel GÓMEZ, and A. Luis del RÍO. "Characterization of endoproteases from plant peroxisomes." Biochemical Journal 327, no. 2 (1997): 399–405. http://dx.doi.org/10.1042/bj3270399.

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In this work, the characterization of endoprotease (EP) isoenzymes in peroxisomes is reported for the first time in cell organelles purified from pea leaves (Pisum sativum L.). A comparative analysis of the endo-proteolytic activity in peroxisomes purified from young (15-day-old) and senescent (50-day-old) leaves was carried out. Peroxisomes purified from senescent leaves showed a much higher endo-proteolytic activity than organelles from young plants. A 16 h incubation with exogenous substrates was the threshold time for the detection of a linear increase in the endo-proteolytic activity of peroxisomes from senescent leaves. Three EP isoenzymes (EP2, EP4 and EP5), having molecular masses of 88, 64 and 50 kDa respectively, were found in young plants by using SDS/polyacrylamide-gradient gels co-polymerized with gelatin. However, four additional isoenzymes (EP1, EP3, EP6 and EP7), with molecular masses of 220, 76, 46 and 34 kDa respectively, were detected in senescent plants. All the isoenzymes detected in peroxisomes from both young and senescent leaves were neutral proteases. By using different class-specific inhibitors, the electrophoretically separated EP isoenzymes were characterized as three serine-proteinases (EP1, EP3 and EP4), two cysteine-proteinases (EP2 and EP6) and a metallo-proteinase (EP7), and EP5 might be a metal-dependent serine-proteinase. Moreover, a peroxisomal polypeptide of 64 kDa was recognized by an antibody against a thiol-protease. The serine-proteinase isoenzymes (EP1, EP3 and EP4), which represent approx. 70% of the total EP activity of peroxisomes, showed a notable thermal stability, not being inhibited by incubation at 50 °C for 1 h.
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Iliev, Atanas, Grzegorz Kapustka, Michał Kapustka, and Kristian Ranestad. "EPW cubes." Journal für die reine und angewandte Mathematik (Crelles Journal) 2019, no. 748 (2019): 241–68. http://dx.doi.org/10.1515/crelle-2016-0044.

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Abstract We construct a new 20-dimensional family of projective six-dimensional irreducible holomorphic symplectic manifolds. The elements of this family are deformation equivalent with the Hilbert scheme of three points on a K3 surface and are constructed as natural double covers of special codimension-three subvarieties of the Grassmannian G(3,6) . These codimension-three subvarieties are defined as Lagrangian degeneracy loci and their construction is parallel to that of EPW sextics, we call them the EPW cubes. As a consequence we prove that the moduli space of polarized IHS sixfolds of K3 -type, Beauville–Bogomolov degree 4 and divisibility 2 is unirational.
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O’Grady, Kieran G. "EPW-sextics: taxonomy." Manuscripta Mathematica 138, no. 1-2 (2011): 221–72. http://dx.doi.org/10.1007/s00229-011-0472-7.

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Kim, Hye-Mi, Peter J. Webster, and Judith A. Curry. "Modulation of North Pacific Tropical Cyclone Activity by Three Phases of ENSO." Journal of Climate 24, no. 6 (2011): 1839–49. http://dx.doi.org/10.1175/2010jcli3939.1.

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Abstract Tropical Pacific Ocean warming has been separated into two modes based on the spatial distribution of the maximum sea surface temperature (SST) anomaly: an east Pacific warming (EPW) and a central Pacific warming (CPW). When combined with east Pacific cooling (EPC), these three regimes are shown to have different impacts on tropical cyclone (TC) activity over the North Pacific by differential modulation of both local thermodynamic factors and large-scale circulation patterns. In EPW years, the genesis and the track density of TCs tend to be enhanced over the southeastern part and suppressed in the northwestern part of the western Pacific by strong westerly wind shear. The extension of the monsoon trough and the weak wind shear over the central Pacific increases the likelihood of TC activity to the east of the climatological mean TC genesis location. In CPW years, the TC activity is shifted to the west and is extended through the northwestern part of the western Pacific. The westward shifting of CPW-induced heating moves the anomalous westerly wind and monsoon trough through the northwestern part of the western Pacific and provides a more favorable condition for TC landfall. The CPW, on the other hand, produces a large suppression of TC activity in the eastern Pacific basin. In EPC years, all of the variables investigated show almost a mirror image of the EPW.
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Sobti, Bhawna, Khulood Jaber Jasim Alnuaimi, Dema Saeed Bakhit Alneyadi, Osha Obaid Essa Almheiri, and Manwa Abdulla Mutaia Alefari. "Characterization and bioactive potential of epicuticular wax from date fruits." Emirates Journal of Food and Agriculture 36 (June 28, 2024): 1–6. http://dx.doi.org/10.3897/ejfa.2024.121959.

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Date fruits (DFs) are lucrative fruits with both nutritional and medicinal benefits. Although DF byproducts have gained interest as potential functional food ingredients, the functional role of DF waxes remains unexplored. Most plant fruits, including DFs,had a lipophilic cuticular layer; and constitutes of epicuticular wax (EPW), which has an important role in respiration losses, mechanical support, fruit softening, and pathogen resistance. In this study, the compositional and antioxidant properties of EPW from Majdool, Khalas, and Fard DFs were investigated. Moreover, thermal transitions of EPW were examined. Results revealed the highest EPW yield in Majdool (16.62 ± 1.68 mg wax/cm2) and the lowest in Khalas (0.075 ± 0.008 mg wax/cm2). Ultraviolet–visible spectroscopy showed maximum absorptivity at 250 and 290 nm across all varieties, corresponding to conjugated dienes and trienes, respectively. Fourier transform infrared peaks confirmed the presence of hydroxyl, methylene, and carbonyl groups, including specific domains of phenolic compounds. Khalas and Fard EPWs reported more total phenolic content and scavenging activity than Majdool EPW. The variations were observed in the melting temperatures of EPW, ranging from 60 °C to 85 °C. These findings establish a theoretical foundation for the potential application of DF EPW in food and pharmaceutical industries.
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Sobti, Bhawna, Khulood Jaber Jasim Alnuaimi, Dema Saeed Bakhit Alneyadi, Osha Obaid Essa Almheiri, and Manwa Abdulla Mutaia Alefari. "Characterization and bioactive potential of epicuticular wax from date fruits." Emirates Journal of Food and Agriculture 36 (June 28, 2024): 1–6. https://doi.org/10.3897/ejfa.2024.121959.

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Date fruits (DFs) are lucrative fruits with both nutritional and medicinal benefits. Although DF byproducts have gained interest as potential functional food ingredients, the functional role of DF waxes remains unexplored. Most plant fruits, including DFs,had a lipophilic cuticular layer; and constitutes of epicuticular wax (EPW), which has an important role in respiration losses, mechanical support, fruit softening, and pathogen resistance. In this study, the compositional and antioxidant properties of EPW from Majdool, Khalas, and Fard DFs were investigated. Moreover, thermal transitions of EPW were examined. Results revealed the highest EPW yield in Majdool (16.62 ± 1.68 mg wax/cm2) and the lowest in Khalas (0.075 ± 0.008 mg wax/cm2). Ultraviolet–visible spectroscopy showed maximum absorptivity at 250 and 290 nm across all varieties, corresponding to conjugated dienes and trienes, respectively. Fourier transform infrared peaks confirmed the presence of hydroxyl, methylene, and carbonyl groups, including specific domains of phenolic compounds. Khalas and Fard EPWs reported more total phenolic content and scavenging activity than Majdool EPW. The variations were observed in the melting temperatures of EPW, ranging from 60 °C to 85 °C. These findings establish a theoretical foundation for the potential application of DF EPW in food and pharmaceutical industries.
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7

Schweda, Frank, Jürgen Klar, Shuh Narumiya, Rolf M. Nüsing, and Armin Kurtz. "Stimulation of renin release by prostaglandin E2 is mediated by EP2 and EP4 receptors in mouse kidneys." American Journal of Physiology-Renal Physiology 287, no. 3 (2004): F427—F433. http://dx.doi.org/10.1152/ajprenal.00072.2004.

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PGE2 is a potent stimulator of renin release. So far, the contribution of each of the four PGE2 receptor subtypes (EP1–EP4) in the regulation of renin release has not been characterized. Therefore, we investigated the effects PGE2 on renin secretion rates (RSR) from isolated, perfused kidneys of EP1−/−, EP2−/−, EP3−/−, EP4−/−, and wild-type mice. PGE2 concentration dependently stimulated RSR from kidneys of all four knockout strains with a threshold concentration of 1 nM in EP1−/−, EP2−/−, EP3−/−, and wild-type mice, whereas the threshold concentration was shifted to 10 nM in EP4−/− mice. Moreover, the maximum stimulation of RSR by PGE2 at 1 μM was significantly reduced in EP4−/− (12.8-fold of control) and EP2−/− (15.9-fold) compared with wild-type (20.7-fold), EP1−/− (23.8-fold), and EP3−/− (20.1-fold). In contrast, stimulation of RSR by either the loop diuretic bumetanide or the β-adrenoceptor agonist isoproterenol was similar in all strains. PGE2 exerted a dual effect on renal vascular tone, inducing vasodilatation at low concentrations (1 nmol/) and vasoconstriction at higher concentrations (100 nmol/) in kidneys of wild-type mice. In kidneys of EP2−/− as well as EP4−/− mice, vasodilatation at low PGE2 concentrations was prevented, whereas vasoconstriction at higher concentrations was augmented. In contrast, the vasodilatatory component was pronounced in kidneys of EP1 and EP3 knockout mice, whereas in both genotypes the vasoconstriction at higher PGE2 concentrations was markedly blunted. Our data provide evidence that PGE2 stimulates renin release via activation of EP2 and EP4 receptors, whereas EP1 and EP3 receptors appear to be without functional relevance in juxtaglomerular cells. In contrast, all four receptor subtypes are involved in the control of renal vascular tone, EP1 and EP3 receptors increasing, and EP2 as well as EP4 receptors, decreasing it.
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Kamaraj, Deepan C., Brad E. Dicianno, and Rory A. Cooper. "A Participatory Approach to Develop the Power Mobility Screening Tool and the Power Mobility Clinical Driving Assessment Tool." BioMed Research International 2014 (2014): 1–15. http://dx.doi.org/10.1155/2014/541614.

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The electric powered wheelchair (EPW) is an indispensable assistive device that increases participation among individuals with disabilities. However, due to lack of standardized assessment tools, developing evidence based training protocols for EPW users to improve driving skills has been a challenge. In this study, we adopt the principles of participatory research and employ qualitative methods to develop the Power Mobility Screening Tool (PMST) and Power Mobility Clinical Driving Assessment (PMCDA). Qualitative data from professional experts and expert EPW users who participated in a focus group and a discussion forum were used to establish content validity of the PMCDA and the PMST. These tools collectively could assess a user’s current level of bodily function and their current EPW driving capacity. Further multicenter studies are necessary to evaluate the psychometric properties of these tests and develop EPW driving training protocols based on these assessment tools.
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Waciński, Witold, Ksawery Kuligowski, Małgorzata Olejarczyk, et al. "Recycling of Industrial Waste as Soil Binding Additives—Effects on Soil Mechanical and Hydraulic Properties during Its Stabilisation before Road Construction." Materials 17, no. 9 (2024): 2000. http://dx.doi.org/10.3390/ma17092000.

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To improve the in situ soil stabilization, different chemical additives are used (ion exchange compounds, additives based on H2SO4 or vinyl polymers, and organic additives using lignosulfonates). One interesting alternative is the production of additives from various waste materials. The extensive testing of waste-based blends with soil was performed; the mechanical (unconfined compressive strength (UCS)) and hydraulic (capillary rise, water absorption, and frost resistance (FR)) soil properties were measured. The optimization process led to obtaining additive compositions ensuring high strength and sealing properties: by-pass ash from the ceramics industry, waste H2SO4, pyrolytic waxes/oils from waste mixed plastics, waste tires and HDPE, and emulsion from chewing gum waste. For sandy soil, the following additives were the most promising: emulsion from pyrolytic wax (EPW) from waste PE foil (WPEF) with the addition of waste H2SO4, pyrolytic-oil emulsion from waste tires, EPW from waste mixed plastics with the addition of “by-pass” waste ash and NaOH, EPW from WPEF with the addition of NaOH, and EPW from WPEF reaching up to 93% FR, a 79.6% 7-day UCS increase, and a 27.6% of 28-day UCS increase. For clay: EPW from WPEF with the addition of NaOH, EPW from WPEF with the addition of waste H2SO4, and solely EPW from WPEF reaching up to 7.5% FR, an 80.7% 7-day UCS increase, and a 119.1% 28-day UCS increase.
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Cao, Qing, Zhenchun Hao, Feifei Yuan, et al. "Impact of ENSO regimes on developing- and decaying-phase precipitation during rainy season in China." Hydrology and Earth System Sciences 21, no. 11 (2017): 5415–26. http://dx.doi.org/10.5194/hess-21-5415-2017.

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Abstract. This study investigated the influence of five El Niño–Southern Oscillation (ENSO) types on rainy-season precipitation in China: central Pacific warming (CPW), eastern Pacific cooling (EPC), eastern Pacific warming (EPW), conventional ENSO and ENSO Modoki. The multi-scale moving t test was applied to determine the onset and withdrawal of rainy season. Results showed that the precipitation anomaly can reach up to 30 % above average precipitation during decaying CPW and EPW phases. Developing EPW could cause decreasing precipitation over large areas in China with 10–30 % lower than average precipitation in most areas. Conventional El Niño in the developing phase had the largest influence on ENSO-related precipitation among developing ENSO and ENSO Modoki regimes. Decaying ENSO also showed a larger effect on precipitation anomalies, compared to decaying ENSO Modoki. The difference between rainy-season precipitation under various ENSO regimes may be attributed to the combined influence of anti-cyclone in the western North Pacific and the Indian monsoon. Stronger monsoon and anti-cyclone are associated with enhanced rainy-season precipitation. The results suggest a certain predictability of rainy-season precipitation related to ENSO regimes.
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Dissertations / Theses on the topic "Epw"

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Beri, Pietro. "On birational transformations and automorphisms of some hyperkähler manifolds." Thesis, Poitiers, 2020. http://www.theses.fr/2020POIT2267.

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Mon travail de thèse porte sur les doubles EPW sextiques, une famille de variétés hyperkähleriennes qui, dans le cas général, sont équivalentes par déformation au schéma de Hilbert de deux points sur une surface K3. Notamment j'ai utilisé le lien que ces variétés ont avec les variétés de Gushel-Mukai, qui sont des variétés de Fano dans une Grassmannienne si leur dimension est plus grande que deux, des surface K3 si la dimension est deux.Le premier chapitre contient quelques rappels de théorie des équations de Pell et des réseaux, qui sont fondamentals pour l’étude des variétés hyperkähleriennes. Ensuite je rappelle la construction qui associe un revêtement double à un faisceau sur une variété normale.Dans le deuxième chapitre j’aborde les variétés hyperkähleriennes et je décris leurs premières propriétés ; j’introduis aussi le premier cas de variété hyperkählerienne qui a été étudiée, les surfaces K3. Cette famille de surfaces correspond aux variétés hyperkähleriennes en dimension deux.Je présente ensuite brièvement certains des derniers résultats dans ce domaine, notamment je définis différents espaces de modules de variétés hyperkähleriennes et je décris l’action d’un automorphisme sur le deuxième groupe de cohomologie d’une variété hyperkähleriennes.Les outils introduits dans le chapitre précédent ne fournissent pas de description géométrique de l'action de l'automorphisme sur la variété, dans le cas où la variété est un schéma de Hilbert de points sur une surface K3. Dans le troisième chapitre, j’introduis donc une description géométrique à une certaine déformation près. Cette déformation prend en compte la structure du schéma de la variété de Hilbert. Pour ce faire, j'introduis un isomorphisme entre une composante connexe de l'espace de modules des variétés de type K3[n] avec une polarization, et l'espace de modules des variétés de même type avec une involution dont le rang de l'invariant est un. Il s’agit d’une généralisation d’un résultat obtenu par Boissière, An. Cattaneo, Markushevich et Sarti en dimension deux. Les deux premières parties de ce chapitre sont un travail en collaboration avec Alberto Cattaneo.Dans le quatrième chapitre, je définis les EPW sextiques, en présentant l'argument de O'Grady, qui montre qu'un double revêtement d'un EPW sextique dans le cas général est une variété de type K3[2]. Ensuite, je présente les variétés Gushel-Mukai, en mettant l'accent sur leur lien avec les EPW sextiques ; cette approche a été introduite par O'Grady, poursuivie par Iliev et Manivel et systématisée par Kuznetsov et Debarre.Dans le cinquième chapitre, j’utilise les outils introduits dans le quatrième chapitre dans le cas où on peut associer une surface K3 à une EPW sextique X. Dans ce cas je donne des conditions explicites sur le groupe de Picard de la surface pour que X soit une variété hyperkählerienne. Cela permet d'utiliser le théorème de Torelli pour une surface K3 pour démontrer l'existence de quelques automorphismes sur X. Je donne des bornes sur la structure d'un sous-groupe d'automorphismes d'une EPW sextique sous conditions d'existence d'un point fixe pour l'action du groupe.Toujours dans le cas d'existence d'une surface K3 associée à une EPW sextique X, j’améliore la borne obtenue précédemment sur les automorphismes de X, en donnant un lien explicite avec le nombre de coniques sur la surface K3. Je montre que la symplecticité d'un automorphisme sur X dépend de la symplecticité d'un automorphisme correspondant sur la surface K3.Le sixième chapitre est un travail en collaboration avec Alberto Cattaneo. J'étudie le groupe d'automorphismes birationels sur le schéma de Hilbert des points sur une surface projective K3, dans le cas générique. Cela généralise le résultat obtenu en dimension deux par Debarre et Macrì. Ensuite j’étudie les cas où il existe un modèle birationel où ces automorphismes sont réguliers. Je décris de façon géométrique quelques involutions dont on avait prouvé l'existence auparavant<br>My thesis work focuses on double EPW sextics, a family of hyperkähler manifolds which, in the general case, are equivalent by deformation to Hilbert's scheme of two points on a K3 surface. In particular I used the link that these manifolds have with Gushel-Mukai varieties, which are Fano varieties in a Grassmannian if their dimension is greater than two, K3 surfaces if their dimension is two.The first chapter contains some reminders of the theory of Pell's equations and lattices, which are fundamental for the study of hyperkähler manifolds. Then I recall the construction which associates a double covering to a sheaf on a normal variety.In the second chapter I discuss hyperkähler manifolds and describe their first properties; I also introduce the first case of hyperkähler manifold that has been studied, the K3 surfaces. This family of surfaces corresponds to the hyperkähler manifolds in dimension two.Furthermore, I briefly present some of the latest results in this field, in particular I define different module spaces of hyperkähler manifolds, and I describe the action of automorphism on the second cohomology group of a hyperkähler manifold.The tools introduced in the previous chapter do not provide a geometrical description of the action of automorphism on the manifold for the case of the Hilbert scheme of points on a general K3 surface. In the third chapter, I therefore introduce a geometrical description up to a certain deformation. This deformation takes into account the structure of Hilbert scheme. To do so, I introduce an isomorphism between a connected component of the module space of manifolds of type K3[n] with a polarization, and the module space of manifolds of the same type with an involution of which the rank of the invariant is one. This is a generalization of a result obtained by Boissière, An. Cattaneo, Markushevich and Sarti in dimension two. The first two parts of this chapter are a joint work with Alberto Cattaneo.In the fourth chapter, I define EPW sextics, using O'Grady's argument, which shows that a double covering of a EPW sextic in the general case is deformation equivalent to the Hilbert square of a K3 surface. Next, I present the Gushel-Mukai varieties, with emphasis on their connection with EPW sextics; this approach was introduced by O'Grady, continued by Iliev and Manivel and systematized by Kuznetsov and Debarre.In the fifth chapter, I use the tools introduced in the fourth chapter in the case where a K3 surface can be associated to a EPW sextic X. In this case I give explicit conditions on the Picard group of the surface for X to be a hyperkähler manifold. This allows to use Torelli's theorem for a K3 surface to demonstrate the existence of some automorphisms on X. I give some bounds on the structure of a subgroup of automorphisms of a sextic EPW under conditions of existence of a fixed point for the action of the group.Still in the case of the existence of a K3 surface associated with a EPW sextic X, I improve the bound obtained previously on the automorphisms of X, by giving an explicit link with the number of conics on the K3 surface. I show that the symplecticity of an automorphism on X depends on the symplecticity of a corresponding automorphism on the surface K3.The sixth chapter is a work in collaboration with Alberto Cattaneo. I study the group of birational automorphisms on Hilbert's scheme of points on a projective surface K3, in the generic case. This generalizes the result obtained in dimension two by Debarre and Macrì. Then I study the cases where there is a birational model where these automorphisms are regular. I describe in a geometrical way some involutions, whose existence has been proved before
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Danielson, Kathryn, and Sean Ustic. "Characterization of the Signaling Properties of FLAG Tagged EP2 and EP4 Prostanoid Receptors." The University of Arizona, 2009. http://hdl.handle.net/10150/623990.

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Class of 2009 Abstract<br>OBJECTIVES: To develop a novel characterization system utilizing immunofluorescent FLAG tagged EP2 and EP4 receptors to assist in the explanation of their unique cell signaling properties for exploitation in future drug development design. METHODS: Plasmids were obtained and isolated that contained cDNAs encoding FLAG-tagged EP2 and EP4 receptors for transient expression in HEK-293 cells. The sequences of these plasmids were confirmed by restriction enzyme analysis and DNA sequencing. Transfected cells were treated with vehicle, PGE2 or forskolin to assess appropriate receptor functionality based on cAMP induction. RESULTS: The two PGE2 receptor subtypes, EP2 and EP4, are similar in their activation of adenylyl cyclase (AC) and subsequent up regulation of cAMP production. These receptors differ, however, in that EP2 more efficiently stimulates cAMP production and EP4 signaling involves the activation of phosphatidylinositol 3-kinase (PI3K) and extracellular signal related kinases (ERKs). The PGE2- treated cells responded as predicted with intracellular production of cAMP, with the EP2 receptor responding more efficiently than the EP4 receptor. CONCLUSIONS: The intent is for these cells to be used as a novel assay system for the development of future selective EP2 and EP4 agonists. This research could potentially benefit in selectively targeting EP2 or EP4 pathways linked to prevalent ailments such as pain, fever, inflammation, possibly cancer or bone growth.
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Thibodeau, Jean-François. "Prostaglandin E2 Signaling Through Kidney EP1 and EP4 Receptors; Implications in Diabetes and Hypertension." Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/32749.

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Chronic kidney disease is defined as the appearance of kidney functional or structural injury. Cyclooxygenase and prostaglandin E2 have been implicated in the pathogenesis of diabetic nephropathy, the leading cause of chronic kidney disease. Beneficial in certain settings, inhibition of the cyclooxygenase pathway can however be detrimental in patients with compromised cardiac or renal function. Moreover, the quest for new therapies to treat diabetic nephropathy is hampered by the lack of appropriate rodent models. This doctoral thesis is a culmination of three studies, the first to determine the role of the prostaglandin E2 EP1 receptor in diabetic nephropathy, the second to elucidate the vascular prostaglandin E2 EP4 receptor’s role in hypertension and lastly to establish and characterise a novel mouse model of diabetic nephropathy. The goal being to uncover new therapeutic avenues for the treatment of CKD, its causes and/or complications.
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Reschke, Cristina Ruedell. "RECEPTORES EP1 E EP3 MODULAM AS CRISES EPILÉPTICAS INDUZIDAS POR PENTILENOTETRAZOL E ÁCIDO CAÍNICO EM CAMUNDONGOS." Universidade Federal de Santa Maria, 2013. http://repositorio.ufsm.br/handle/1/3852.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Epilepsy is one of the most common neurologic disorders. It has been suggested that seizures may be facilitaded by inflammation. PGE2 is one of the most important inflammatory mediators, and facilitates pentylenetetrazol (PTZ)-induced seizures by stimulating EP1 and EP3 receptors. However, up to the present moment, no study has investigated whether EP1 and EP3 receptors blocking attenuate seizures induced by convulsants other than PTZ. It is also unknown whether Na+,K+-ATPase activity alterations are involved in such an effect. Therefore, in the current study we investigated whether EP1 and EP3 ligands (agonists and antagonists) modulate PTZ- and kainic acid (KA)-induced seizures, and whether alterations in Na+,K+-ATPase activity mediate such a protective effect, in mice. EP1 and EP3 antagonists (ONO-8713 and ONO-AE3-240, respectively, 10 Og/kg, s.c.) attenuated PTZ (60 mg/kg, i.p.)- and KA (20 mg/kg, i.p.)-induced seizures. The respective agonists (ONO-DI-004 and ONO-AE-248, 10 Og/kg, s.c.) facilitated seizures in both acute models, and at noneffective doses, prevented the protective effects of the antagonists. Animals injected with PTZ presented decreased Na+,K+-ATPase activity in the cerebral cortex and hippocampus. On the other hand, animals injected with KA presented increased Na+,K+-ATPase activity in the same cerebral structures at the end of the experiment. These divergent findings suggest that alterations in Na+,K+-ATPase activity in both acute models depends on the convulsant agent used and make difficult to establish a relationship between Na+,K+-ATPase activity and seizure development. Moreover, EP1 and EP3 antagonists administration abolished Na+,K+- ATPase activity alterations induced by PTZ and KA, in such a way that these alterations seem to be related more to the presence of ictal phenomenon itself than to the seizure induction mechanisms. Notwithstanding, the currrent results clearly show that EP1 and EP3 receptors might constitute novel targets for anticonvulsants development, since EP1 and EP3 decreased seizures, regardless of the convulsant agent used.<br>A epilepsia é uma das disfunções neurológicas mais comuns. Tem sido sugerido que as crises epilépticas podem ser facilitadas pela ocorrência de inflamação. A PGE2 é um dos mediadores inflamatórios mais importantes que, agindo por meio dos receptores EP1 e EP3, facilita as convulsões induzidas por pentilenotetrazol (PTZ). Contudo, até a presente data, nenhum estudo investigou, de maneira sistêmica, se a ativação ou bloqueio de receptores EP1 e EP3 facilitam as convulsões induzidas por outros agentes; tampouco se alterações na atividade da Na+,K+-ATPase estão envolvidas nesse efeito. Assim, no presente estudo, investigamos se ligantes (agonistas e antagonistas) de receptores EP1 e EP3 modificam as crises induzidas por PTZ e ácido caínico (KA), e se tais efeitos estão associados a alterações na atividade da enzima Na+,K+-ATPase, em camundongos. Os antagonistas EP1 e EP3 (ONO-8713 e ONO-AE3-240, respectivamente, 10 Og/Kg, s.c.) atenuaram as convulsões induzidas por PTZ (60 mg/Kg, i.p.) e KA (20 mg/Kg). Os seus respectivos agonistas (ONO-DI-004 e ONO-AE-248 de 10 Og/Kg, s.c.) facilitaram as convulsões em ambos modelos agudos de crises epilépticas e, em doses não efetivas para gerar crises, preveniram os efeitos dos antagonistas. Os animais submetidos à administração de PTZ apresentaram, ao final do experimento, a atividade Na+,K+-ATPásica diminuída no córtex cerebral e hipocampo. Por outro lado, animais tratados com KA apresentaram um aumento na atividade Na+,K+-ATPásica nestas mesmas estruturas, que se correlacionou positivamente com a vigência de status epilepticus no momento do sacrifício. Os achados divergentes no que diz respeito à alteração da atividade da Na+,K+-ATPase nos dois modelos de crises agudas sugere que tais alterações estejam relacionadas ao tipo de agente convulsivante utilizado, e dificultam estabelecer, de forma inequívoca, uma relação entre atividade desta ATPase e sensibilidade à crises agudas. Ademais, a administração de antagonistas EP1 e EP3 aboliu as alterações da atividade da Na+,K+-ATPase induzidas tanto por PTZ como por KA, de tal forma que estas parecem estar mais associadas com o fenômeno ictal em si, do que com os mecanismos de indução da crise. Contudo, os resultados mostram de forma clara que os receptores EP1 e EP3 podem se constituir possíveis novos alvos para o desenvolvimento de drogas antiepilépticas, pois antagonistas EP1 e EP3 diminuíram as crises, independente do agente convulsivante utilizado.
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Chandra, Divya. "To evaluate differences in mRNA expression of c-fms, EP2 and EP4 between large and small osteoclasts." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ62999.pdf.

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Miyamoto, Masatomo. "Simultaneous stimulation of EP2 and EP4 is essential to the effect of prostaglandin E2 in chondrocyte differentiation." Kyoto University, 2004. http://hdl.handle.net/2433/147477.

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Honda, Tetsuya. "Prostacyclin-IP signaling and prostaglandin E2-EP2/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis." Kyoto University, 2007. http://hdl.handle.net/2433/135661.

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Norén, Pontus. "Uppfinningshöjd och datorrelaterade uppfinningar." Thesis, Uppsala universitet, Juridiska institutionen, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-195985.

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西垣, 信裕. "プロスタグランジンE受容体サブタイプEP2及びEP4の機能特性に関する研究". 京都大学 (Kyoto University), 1997. http://hdl.handle.net/2433/202489.

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Berliner, Julia [Verfasser], and Gunther [Akademischer Betreuer] Zahner. "Die Rolle der Prostaglandinrezeptoren EP2 und EP4 bei Foxp3-positiven T-regulatorischen Zellen in der nephrotoxischen Serumnephritis der Maus / Julia Berliner. Betreuer: Gunther Zahner." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2013. http://d-nb.info/1036729451/34.

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Books on the topic "Epw"

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Gassier, Jacqueline. Biologie, nutrition-alimentation: EP2/EP4, Concours AS/AP. 3rd ed. Masson, 2005.

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J, Eysenck H. Manual of the Eysenck personality scales (EPS adult): Comprising the EPQ-revised (EPQ-R) (including addiction and criminality scales), EPQ-R short scale impulsiveness (IVE) questionnaire (impulsiveness/venturesomeness/empathy). Hodder & Stoughton, 1991.

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Moran, Matías. Epu. Editorial La Noria, 1986.

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Morán, Matías. Epu. Editorial La Noria, 1986.

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United States. Environmental Protection Agency. Information Access Branch. Access EPA: Major EPA dockets. Information Access Branch, Information Management and Services Division, U.S. Environmental Protection Agency, 1991.

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United States. Environmental Protection Agency. Information Access Branch. Access EPA: Major EPA dockets. Information Access Branch, Information Management and Services Division, U.S. Environmental Protection Agency, 1991.

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R, Eaton Gareth, Eaton Sandra S, and Ohno Keiicho, eds. EPR imaging and in vivo EPR. CRC Press, 1991.

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United States. Environmental Protection Agency. Information Access Branch. Access EPA: Major EPA environmental databases. Information Access Branch, Information Management and Services Division, U.S. Environmental Protection Agency, 1991.

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United States. Environmental Protection Agency. Information Access Branch. Access EPA: Major EPA environmental databases. Information Access Branch, Information Management and Services Division, U.S. Environmental Protection Agency, 1991.

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Drescher, Malte, and Gunnar Jeschke, eds. EPR Spectroscopy. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-28347-5.

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Book chapters on the topic "Epw"

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Bartoldus, C. C. "EPW: A Procedure for the Functional Assessment of Planned Wetlands." In Wetlands of the Interior Southeastern United States. Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-6579-2_20.

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Bährle-Rapp, Marina. "epi..., Epi..., auch: ep..., Ep...; eph..., Eph..." In Springer Lexikon Kosmetik und Körperpflege. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_3599.

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Cochran, Timothy B. "Epilogue." In Musical Sincerity and Transcendence in Film. Routledge, 2021. http://dx.doi.org/10.4324/9780429464126-ep1.

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Khan, Aamer. "Epilogue." In Regenerative Medicine in Aesthetic Treatments. CRC Press, 2021. http://dx.doi.org/10.1201/9781003001478-epi.

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Ellenbroek, Bart, Alfonso Abizaid, Shimon Amir, et al. "EPS." In Encyclopedia of Psychopharmacology. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_4238.

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LaCaille, Lara, Anna Maria Patino-Fernandez, Jane Monaco, et al. "EPA." In Encyclopedia of Behavioral Medicine. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1005-9_100568.

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Wick, David. "EPR." In The Infamous Boundary. Birkhäuser Boston, 1995. http://dx.doi.org/10.1007/978-1-4612-5361-7_9.

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"EPR correlations and EPW distributions." In Speakable and Unspeakable in Quantum Mechanics. Cambridge University Press, 2004. http://dx.doi.org/10.1017/cbo9780511815676.023.

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Bell, J. S. "EPR Correlations and EPW Distributions." In John S Bell on the Foundations of Quantum Mechanics. WORLD SCIENTIFIC, 2001. http://dx.doi.org/10.1142/9789812386540_0018.

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Bell, J. S. "EPR Correlations and EPW Distributions." In World Scientific Series in 20th Century Physics. WORLD SCIENTIFIC, 1995. http://dx.doi.org/10.1142/9789812795854_0088.

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Conference papers on the topic "Epw"

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Sharma, Parul, Brijesh Kumar, Lekshmi Eswaramoorthy, and Anshuman Kumar. "Terahertz half-wave plate leveraging Exceptional Points in Non-Hermitian System." In Frontiers in Optics. Optica Publishing Group, 2024. https://doi.org/10.1364/fio.2024.jw4a.51.

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This study explores terahertz (THz) optical sensors leveraging exceptional points (EPs) in non-Hermitian systems, using split-ring resonators. We demonstrate the use of anisotropic metasurface as half-wave plates and their enhanced conversion efficiency around EP.
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Stadler, Reinhard, Wolfram Fuerbeth, Mariel Grooters, Claudia Janosch, Andrzej Kuklinski, and Wolfgang Sand. "Studies on the Application of Microbially Produced Polymeric Substances as Protecting Layers against Microbially Influenced Corrosion of Iron and Steel." In CORROSION 2010. NACE International, 2010. https://doi.org/10.5006/c2010-10209.

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Abstract The contribution of biofilms to corrosion of metals and alloys, termed microbially influenced corrosion (MIC), is still a challenge for research in the field of corrosion protection. In order to inhibit or prevent MIC, one promising route can be to inhibit the adhesion of single cells. The processes of adhesion and desorption of microorganisms are known to be induced and mediated by various (bio-)molecules. The aim of this project is to identify and to investigate substances appropriate to inhibit the formation of biofilms of sulphate reducing bacteria (SRB). For this purpose, so-called extracellular polymeric substances (EPS) of various bacteria have been harvested from biofilms and purified. These substances have been analyzed with focus on chemical groups like proteins, carbohydrates or glucuronic acids. The EPS have been adsorbed on metal substrates in order to form layers probably protecting against adhesion of Desulfovibrio vulgaris. Layer formation and adhesion of bacteria were studied by epi-fluorescence microscopy (EFM) and atomic force microscopy (AFM). It was observed that the number of attached cells was significantly lower on the covered surfaces when compared to pure substrates. Additionally, most of the EPS were found to be resistant against degradation by Desulfovibrio vulgaris.
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Hach, Edwin E., Christopher C. Gerry, Richard Birrittella, and Paul M. Alsing. "The EPR Cat." In Next-Generation Spectroscopic Technologies XVII, edited by Steven M. Barnett and Luisa T. M. Profeta. SPIE, 2025. https://doi.org/10.1117/12.3054025.

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Hornak, Joseph. "The EPR MOUSE." In Next-Generation Spectroscopic Technologies XVII, edited by Steven M. Barnett and Luisa T. M. Profeta. SPIE, 2025. https://doi.org/10.1117/12.3053990.

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Kaelin, Alison B. "Here Comes EPA: Trends in EPA Enforcement in the Coatings Industry." In SSPC 2000. SSPC, 2000. https://doi.org/10.5006/s2000-00026.

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Abstract While the industrial painting industry has long recognized the potential impact of EPA regulations on projects, there has been relatively little regulatory enforcement by the EPA (and state agencies) in the past 13 years. This paper provides an overview of the increasing regulatory interest in the environmental aspects of the industrial painting industry. It summarizes recent regulatory actions against industrial painting contractors and owners based upon environmental statutes such as the Resource Conservation and Recovery Act, the Comprehensive Environmental Response, Compensation and Liability Act, Clean Air Act, and Clean Water Act.
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Boren, Arthur D., Jan W. Pawlak, and Timothy J. Stultz. "Commercialization of evanescent planar waveguide (EPW) technology." In BiOS 2001 The International Symposium on Biomedical Optics, edited by Gerald E. Cohn. SPIE, 2001. http://dx.doi.org/10.1117/12.426746.

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Gacem, A., N. Nadjar-Gauthier, E. Monacelli, T. Al-ani, and Y. Oussar. "Behavior Identification for Wheelchair Driver Using the Fuzzy C-Means Classification Method." In ASME 2012 11th Biennial Conference on Engineering Systems Design and Analysis. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/esda2012-82874.

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This study deals with behavior identification of Electric-Powered Wheelchair (EPW) drivers. User’s actions on the joystick determine this behavior. We assume that a driver evaluation can be performed using reference behaviors which are determined a priori. This study was carried out with two valid populations. The first one includes eight experimented subjects. The second includes six novice subjects. We propose to implement the Fuzzy C-Means (FCM) classification to separate different behaviors. The FCM was applied on the experimented population in order to determine reference’s behaviors. This shows that there were basically two different behaviors. An evaluation is performed on novice users by comparing their behaviors with respect to the reference ones. The results show that this population has an erratic behavior during the learning phase. Subsequently, users converge to one of the identified reference behaviors. We also evaluated a subject who suffers from muscular dystrophy and uses an EPW in everyday life. The results show a steady driving behavior.
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Alsibai, Mohammed Hayyan, Mhd Saeed Sharif, Salma Yaakub, and Nurul Nadia Nor Hamran. "An innovative EPW design using add-on features to meet Malaysian requirements." In 2017 7th IEEE International Conference on Control System, Computing and Engineering (ICCSCE). IEEE, 2017. http://dx.doi.org/10.1109/iccsce.2017.8284401.

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McCullough, III, F. Albert. "Guide to Functional Design Using the Evaluation for Planned Wetlands (EPW) Procedure." In Wetlands Engineering and River Restoration Conference 1998. American Society of Civil Engineers, 1998. http://dx.doi.org/10.1061/40382(1998)130.

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Pearlman, Jon, Rory Cooper, H. S. Chhabra, Alexandra Jefferds, and Ilanagai Anbarasan. "A Low-Cost Tool for Gathering and Interpreting the Mobility Needs of Wheelchair Users in India." In ASME 2009 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2009. http://dx.doi.org/10.1115/detc2009-86734.

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Collecting and interpreting customer needs using traditional product development tools can be difficult or impossible when there is a large geographic, cultural, or social gap between the customer and product designer. As part of a project to design an electric powered wheelchair (EPW) for Indians with disabilities, we piloted a new approach to gather and interpret customer needs. First, we distributed cameras to manual wheelchair users at the Indian Spinal Injury Center in New Delhi, India, and asked subjects take photos and write descriptions of accessibility barriers in and around their homes. The film was then processed; photos were de-identified and integrated into an internet-based questionnaire. Individuals with expertise in wheelchair use and design, and home modifications were recruited to participate in the questionnaire where they identified and ranked the accessibility barriers in each of 50 images which were randomly selected from the full database. Thirty cameras were received, yielding approximately 500 photos which were integrated into the questionnaire. A total of 72 subjects from 8 countries participated in the questionnaire. Using cluster analysis, we developed unique groupings for accessibility barriers based on their severity and prevalence. These groupings provided valuable and relevant information to develop and prioritize the design specifications of the EPW.
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Reports on the topic "Epw"

1

Lawrence, Christopher A., Richard C. Anderson, and Jr. Capture Rate Study: Medical Requirements for EPW Phase IV (Part 1). Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada401068.

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Huey, John M. Transitioning from Enemy Prisoner of War EPW" Operations to Long-Term Detainee Operations". Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada469596.

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Noll, James P. The 13th Psychological Operations Battalion (EPW) during Mobilization, Desert Shield / Desert Storm and Demobilization. Defense Technical Information Center, 1993. http://dx.doi.org/10.21236/ada264579.

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CHEN, KENNETH C., and WILLIAM P. BRIGHAM. EBW Gapping Study. Office of Scientific and Technical Information (OSTI), 2001. http://dx.doi.org/10.2172/810620.

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Hahn, Howard, and Timothy R. Kellams. EPA Region 7 Headquarters. Landscape Architecture Foundation, 2016. http://dx.doi.org/10.31353/cs1050.

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Hollenbeck, S. Extensible Provisioning Protocol (EPP). RFC Editor, 2004. http://dx.doi.org/10.17487/rfc3730.

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Hollenbeck, S. Extensible Provisioning Protocol (EPP). RFC Editor, 2007. http://dx.doi.org/10.17487/rfc4930.

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Hollenbeck, S. Extensible Provisioning Protocol (EPP). RFC Editor, 2009. http://dx.doi.org/10.17487/rfc5730.

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Boppart, Timo, Karl Harmenberg, John Hassler, Per Krusell, and Jonna Olsson. Integrated Epi-Econ Assessment. National Bureau of Economic Research, 2020. http://dx.doi.org/10.3386/w28282.

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WEBB, IAN, and KLAEHN BURKES. SRNL EPC INSTALLATION REPORT. Office of Scientific and Technical Information (OSTI), 2021. http://dx.doi.org/10.2172/1834723.

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