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Journal articles on the topic 'ERDF'

Author: Grafiati
Published: 4 June 2021
Last updated: 9 March 2023

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1

Ananna, Tonima Tasnim, Anna K. Weigel, Benny Trakhtenbrot, Michael J. Koss, C. Megan Urry, Claudio Ricci, Ryan C. Hickox, et al. "BASS. XXX. Distribution Functions of DR2 Eddington Ratios, Black Hole Masses, and X-Ray Luminosities." Astrophysical Journal Supplement Series 261, no. 1 (July 1, 2022): 9. http://dx.doi.org/10.3847/1538-4365/ac5b64.

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Abstract We determine the low-redshift X-ray luminosity function, active black hole mass function (BHMF), and Eddington ratio distribution function (ERDF) for both unobscured (Type 1) and obscured (Type 2) active galactic nuclei (AGNs), using the unprecedented spectroscopic completeness of the BAT AGN Spectroscopic Survey (BASS) data release 2. In addition to a straightforward 1/V max approach, we also compute the intrinsic distributions, accounting for sample truncation by employing a forward-modeling approach to recover the observed BHMF and ERDF. As previous BHMFs and ERDFs have been robustly determined only for samples of bright, broad-line (Type 1) AGNs and/or quasars, ours are the first directly observationally constrained BHMF and ERDF of Type 2 AGNs. We find that after accounting for all observational biases, the intrinsic ERDF of Type 2 AGNs is significantly more skewed toward lower Eddington ratios than the intrinsic ERDF of Type 1 AGNs. This result supports the radiation-regulated unification scenario, in which radiation pressure dictates the geometry of the dusty obscuring structure around an AGN. Calculating the ERDFs in two separate mass bins, we verify that the derived shape is consistent, validating the assumption that the ERDF (shape) is mass-independent. We report the local AGN duty cycle as a function of mass and Eddington ratio, by comparing the BASS active BHMF with the local mass function for all supermassive black holes. We also present the log N − log S of the Swift/BAT 70 month sources.
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Vehkasalo, Ville. "Effectiveness of EU Regional Policy: Evidence from a Natural Experiment in Finland." REGION 5, no. 3 (July 2, 2018): 1–19. http://dx.doi.org/10.18335/region.v5i3.195.

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European Union regional policy is implemented through structural funds, such as the European Regional Development Fund (ERDF), which support investment in peripheral regions of the EU. We studied the effects of EU regional policy on key economic variables using a rare natural experiment setting. In 2007, parts of regions that were previously covered by the ERDF programme for Western Finland were reallocated to the ERDF programme for Northern Finland, with higher support intensity per capita. This area reallocation was caused by the newly adopted EU legislation regulating the classification of regional statistical areas. With a detailed postal code area dataset and a difference-in-differences estimator, we discovered desirable regional policy effects on unemployment and the number of jobs.
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Panfiluk, Eugenia. "Analysis of the effectiveness in the disbursement of the European Regional Development Fund for selected entities in the tourism economy." Ekonomia i Zarzadzanie 8, no. 4 (December 1, 2016): 39–49. http://dx.doi.org/10.1515/emj-2016-0031.

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Abstract The aim of the article is to analyse the effectiveness of decision-making in the disbursement of funds from the ERDF for the selected tourism services. In the theoretical part of the article, the model for the assessment of the effectiveness of the ERDF management system was developed. This model is built based on the Propensity Score Matching (PSM) method, used to assess the effectiveness of community programmes. In the empirical part of the article, the verification of the model was carried out following the example of the tourism sector of the NUTS 2 region of Podlasie. The obtained results allow concluding that the developed deadweight assessment model can be used in practice for the evaluation of the efficiency of the ERDF management. The conducted research indicates that the method of Propensity Score Matching (PSM), using the Neyman-Rubin model based on counterfactual studies, allows assessing the decision-making effectiveness in the disbursement of funds from the ERDF. Creating counterfactual situations in the models of evaluation of infrastructural actions serves for the identification of the effect of an independent event. The effect of an independent event measures the negative, unintended consequences of the undertaken decisions. It informs about the loss of alternative possibilities of allocating funds for other purposes.
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Analyti, Anastasia, Grigoris Antoniou, Carlos Viegas Damásio, and Ioannis Pachoulakis. "A framework for modular ERDF ontologies." Annals of Mathematics and Artificial Intelligence 67, no. 3-4 (March 2013): 189–249. http://dx.doi.org/10.1007/s10472-013-9350-1.

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Henriques, Carla, and Clara Viseu. "Are ERDFs Devoted to Boosting ICTs in SMEs Inefficient? A Three-Stage SBM Approach." Sustainability 14, no. 17 (August 24, 2022): 10552. http://dx.doi.org/10.3390/su141710552.

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We assessed the implementation of operational programs (OPs) aimed at boosting the deployment of information and communication technologies (ICTs) in small and medium-sized enterprises (SMEs). We performed a three-stage slack-based measure (SBM) data envelopment analysis (DEA) model combined with the stochastic frontier analysis (SFA), which considered data and contextual factors reported from the European Union (EU) to appraise 51 OPs from 16 countries. Overall, we discovered that by eliminating the contextual factors, almost 27% of the OPs (14) attained efficient procedural results. The OP “Multi-regional Spain—ERDF” is widely perceived as a benchmark, irrespective of its contextual factors, remaining robustly efficient for data perturbations ranging from 5% to 10%. The “Number of Operations Supported” is the indicator that requires attention, both with or without the removal of contextual factors. Our findings suggest that more developed regions, with a greater proportion of ICT professionals, are associated with a poor utilization and allocation of ERDF funds to promote ICT adoption in SMEs. This could be attributed to an inability of SMEs to handle the complex bureaucratic processes of submitting and executing European Regional Development Fund (ERDF) initiatives. Consequently, it is vital to provide additional assistance that streamlines the management formalities and satisfies the needs of SMEs.
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Beņkovskis, Konstantīns, Oļegs Tkačevs, and Naomitsu Yashiro. "Importance of EU regional support programmes for firm performance*." Economic Policy 34, no. 98 (April 1, 2019): 267–313. http://dx.doi.org/10.1093/epolic/eiz003.

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Summary This paper investigates the effects of EU regional support on firm productivity, the number of employees and other performance indicators. We use a rich firm-level dataset for Latvia – the country, where investment activities are largely affected by the availability of EU funding. After controlling for the fact that more productive and larger firms are more likely to acquire EU finds, we find that participation in projects co-financed by the European Regional Development Fund (ERDF) increases firms’ employment, turnover and capital stock per employee immediately, while it raises their productivity only two years after the launch of the projects. ERDF beneficiaries that are initially less productive, larger, less capital intensive and more financially leveraged enjoy larger productivity gains.
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Lowe, Antony, Susan Goh, Geoff Heppell, Robin Scott, and Keith Ridgway. "Promoting Manufacturing Excellence in SMEs." Industry and Higher Education 14, no. 4 (August 2000): 260–64. http://dx.doi.org/10.5367/000000000101295174.

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The Ibberson Laboratory is a centre established at the University of Sheffield, partly financed by the European Community's Regional Development Fund (ERDF), to provide support for manufacturing small and medium-sized enterprises (SMEs) in the South Yorkshire region of the UK. Initiated in November 1998, the Laboratory aids firms by providing technical expertise and access to advanced manufacturing equipment and manpower. These are applied in graduate placements and short-term projects that focus on new product/process development and technology transfer. This paper describes the background to the project and details the objectives, structure and operation of the Laboratory. A typical project scenario is outlined and the performance measures to be achieved in meeting the requirements of ERDF funding are discussed. Finally, the progress of the Ibberson Laboratory towards meeting these measures is reported.
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8

Liot, Dominique. "Perte de sens au travail à erdf-grdf." Empan 77, no. 1 (2010): 26. http://dx.doi.org/10.3917/empa.077.0026.

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Gouveia, Maria, Carla Henriques, and Ana Amaro. "Is the Cohesion Policy Efficient in Supporting the Transition to a Low-Carbon Economy? Some Insights with Value-Based Data Envelopment Analysis." Sustainability 14, no. 18 (September 15, 2022): 11587. http://dx.doi.org/10.3390/su141811587.

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We evaluated the implementation of European Regional Development Funds (ERDF) devoted to Thematic Objective (TO) 4 in 23 beneficiary European Union (EU) Member States (MS). The assessment of each country was made through the value-based data envelopment analysis (VBDEA) approach in three phases. In the first phase, it was possible to conclude that 43% of the MS were efficient in the implementation of the ERDF devoted to a low-carbon economy (LCE), and the reasons for their efficiency were mainly explained by their execution rate. After running the second phase for the inefficient countries, it was possible to obtain the improvements that must be made for these countries to “emulate” their peers at the efficient frontier. Finally, in the third stage, we incorporated political concerns in the evaluation of the implementation of the ERDF by including constraints on the ranking order of the weights. A robustness analysis was also carried out, according to which it was found that only 22% of the MS under evaluation remained surely efficient for tolerances of δ = 5% and δ = 10%, with Spain being the most robust country. Other countries such as Romania (surely inefficient for δ = 5%), Hungary, and the Czech Republic (the most inefficient) did not manage to implement these funds efficiently. Considering these findings, the EU needs to further promote policies that ensure economic benefits from investing in an LCE, specifically for countries with fewer resources, while also providing them with better financial conditions and know-how.
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Henriques, Carla, and Clara Viseu. "How Efficient Is the Implementation of Structural Funds Committed to Enhancing ICT Adoption in SMEs?" Journal of Open Innovation: Technology, Market, and Complexity 8, no. 3 (August 23, 2022): 147. http://dx.doi.org/10.3390/joitmc8030147.

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We evaluated the execution of the operational programs (OPs) committed to encouraging the adoption of information and communication technologies (ICTs) in small and medium-sized enterprises (SMEs). To achieve this goal, we employed a novel three-stage weighted Russel directional distance (WRDD) data envelopment analysis (DEA) model in conjunction with stochastic frontier analysis (SFA), which considers indicators officially mandated by the European Union (EU) and environmental factors, to evaluate 51 OPs from 16 EU countries. All in all, we concluded that by removing the environmental factors, about 30% of the OPs (16) reached an efficient procedural performance against 20% (10). The OP more frequently viewed as a benchmark regardless of the environmental factors is “Multi-regional Spain—ERDF” that remains robustly efficient within 5% and 10% tolerances. Without the removal of the environmental factors, the “number of operations supported” is the indicator that requires more attention from management authorities (MAs), whereas with their removal one-third of the OPs need to further reduce the “eligible costs decided” and improve “eligible spending”. According to our findings, more developed regions and a higher rate of ICT specialists seem to be related to an underuse of ERDF funds dedicated to boosting ICT in SMEs. These findings might be related to the administrative burden and the lack of ability of SMEs to deal with the various procedures for applying for and implementing European Regional Development Fund (ERDF) projects. Overall, it is critical to provide further support that simplifies administrative procedures and addresses SMEs’ specific requirements.
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De Guerrero Manso, Carmen. "The promotion of integrated sustainable urban development by the European Union and its application in Aragon." WPS Review International on Sustainable Housing and Urban Renewal, no. 6 (December 23, 2017): 82–105. http://dx.doi.org/10.24310/wps.vi6.13797.

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Europe 2020, a strategy for Smart, sustainable and inclusive growth, wants to mark a new beginning in which Europe emerges stronger from the economic and financial crisis. This strategy aims at a different type of growth, smart, sustainable and inclusive, and it seeks to create the right conditions to achieve such kind of growth. All these aspects are especially involved in cities, because they are spatial concentrations of human activity and interactions between their inhabitants. In line with this importance of cities in implementing the Europe 2020 strategy, the urban dimension of Cohesion Policy has been significantly strengthened for the 2014-2020 period. In the case of the ERDF, Member States are now obliged to allocate at least 5% of their national ERDF budget to support integrated sustainable urban development strategies. In this paper we analyse the regulation of this new tool aimed at achieving sustainable and integrated urban development and its implementation in the Autonomous Community of Aragon.
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12

Analyti, A., G. Antoniou, C. V. Damasio, and G. Wagner. "Extended RDF as a Semantic Foundation of Rule Markup Languages." Journal of Artificial Intelligence Research 32 (May 15, 2008): 37–94. http://dx.doi.org/10.1613/jair.2425.

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Ontologies and automated reasoning are the building blocks of the Semantic Web initiative. Derivation rules can be included in an ontology to define derived concepts, based on base concepts. For example, rules allow to define the extension of a class or property, based on a complex relation between the extensions of the same or other classes and properties. On the other hand, the inclusion of negative information both in the form of negation-as-failure and explicit negative information is also needed to enable various forms of reasoning. In this paper, we extend RDF graphs with weak and strong negation, as well as derivation rules. The ERDF stable model semantics of the extended framework (Extended RDF) is defined, extending RDF(S) semantics. A distinctive feature of our theory, which is based on Partial Logic, is that both truth and falsity extensions of properties and classes are considered, allowing for truth value gaps. Our framework supports both closed-world and open-world reasoning through the explicit representation of the particular closed-world assumptions and the ERDF ontological categories of total properties and total classes.
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13

Chua, Florence, Steve K. W. Oh, Miranda Yap, and Wah Koon Teo. "Enhanced IgG production in eRDF media with and without serum." Journal of Immunological Methods 167, no. 1-2 (January 1994): 109–19. http://dx.doi.org/10.1016/0022-1759(94)90080-9.

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BONATESTA, Antonio. "The ERDF and the Mezzogiorno: The Case of Apulia (1972-1992)." Journal of European Integration History 23, no. 2 (2017): 227–44. http://dx.doi.org/10.5771/0947-9511-2017-2-227.

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Ohkubo, T., and K. Kaneko. "Oriented structures of alcohol hidden in carbon micropores with ERDF analysis." Colloids and Surfaces A: Physicochemical and Engineering Aspects 187-188 (August 2001): 177–85. http://dx.doi.org/10.1016/s0927-7757(01)00627-6.

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Shanmugam, Janaki, Konstantin B. Borisenko, Yu-Jen Chou, and Angus I. Kirkland. "eRDF Analyser: An interactive GUI for electron reduced density function analysis." SoftwareX 6 (2017): 185–92. http://dx.doi.org/10.1016/j.softx.2017.07.001.

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17

Anderson, Jeffrey J. "Skeptical Reflections on a Europe of Regions: Britain, Germany, and the ERDF." Journal of Public Policy 10, no. 4 (October 1990): 417–47. http://dx.doi.org/10.1017/s0143814x00006073.

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ABSTRACTEuropean Community policymaking has been predicated upon the member governments acting as gatekeepers which mediate between their respective domestic political systems and EC institutions. However, the sweeping changes associated with Project 1992 threaten the gatekeeping status of the Twelve. This article explores the domestic and international consequences, which are cast in terms of three scenarios: the maintenance of the status quo, the emergence of a ‘Europe of Regions’, and a variegated set of outcomes. As an attempt to move beyond the realm of pure speculation, concrete lessons are culled from the reform of the European Regional Development Fund since 1979 and its effect on national and subnational interests in Britain and the Federal Republic of Germany. The theoretical premise is that national and subnational actors respond to Community initiatives within a structured context, the domestic policy networks in which they are embedded. These clusters of interorganizational relationships at the domestic level reflect the underlying distribution of resources among actors, and endow them with different capabilities and vulnerabilities as they seek to cope with changes administered to their policy environment by the EC. The findings suggest skepticism of the image of strengthened regions breaking out of the orbit of weakened states with the assistance of the EC. While the ability of member states to retain their roles as gatekeepers varies, this capacity remains strong. Moreover, subnational actors often view the EC as yet another exogenous institutional constraint on action.
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McLeod-Kilmurray, Heather. "13 Stichting Greenpeace and Environmental Public Interest Standing before the Community Judicature: Some lessons from the Federal Court of Canada." Cambridge Yearbook of European Legal Studies 1 (1998): 269–306. http://dx.doi.org/10.5235/152888712802821124.

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On April 2,1998, three years after the ruling of the Court of First Instance, the European Court of Justice issued its appeal decision in the Stichting Greenpeace case. The Court of First Instance had denied locus standi under Article 230(4) (Article 173(4)) of the EC Treaty to Greenpeace, two local environmental groups and a series of individual applicants to challenge the decision of the European Commission to continue providing Community structural funds under the European Regional Development Fund (ERDF) to Spain to build two power stations in the Canary Islands.
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McLeod-Kilmurray, Heather. "Stichting Greenpeace and Environmental Public Interest Standing before the Community Judicature: Some lessons from the Federal Court of Canada." Cambridge Yearbook of European Legal Studies 1 (1998): 269–306. http://dx.doi.org/10.1017/s1528887000001178.

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On April 2,1998, three years after the ruling of the Court of First Instance, the European Court of Justice issued its appeal decision in the Stichting Greenpeace case. The Court of First Instance had denied locus standi under Article 230(4) (Article 173(4)) of the EC Treaty to Greenpeace, two local environmental groups and a series of individual applicants to challenge the decision of the European Commission to continue providing Community structural funds under the European Regional Development Fund (ERDF) to Spain to build two power stations in the Canary Islands.
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Hedfeldt, Mona, and Gun Hedlund. "A Clash between the Business and Political Climates in Sweden – Gender in the European Structural Fund Partnerships." European Spatial Research and Policy 18, no. 1 (June 16, 2011): 53–69. http://dx.doi.org/10.2478/v10105-011-0004-1.

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In this paper we highlight and discuss a Swedish equality paradox in two different spheres: entrepreneurship and politics. We focus on the EU Structural Funds and women entrepreneurs' access to resources through the European Regional Development Fund (ERDF). Combining human geography and political science, we draw upon network and partnership theory posing questions concerning the room for manoeuvre for women entrepreneurs to gain access to relevant networks, to create new networks in order to establish relations with EU related partnerships, and to gain access to the process of allocating EU structural fund financial resources.
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Chua, Florence K. F., Miranda G. S. Yap, and Steve K. W. Oh. "Hyper-stimulation of monoclonal antibody production by high osmolarity stress in eRDF medium." Journal of Biotechnology 37, no. 3 (November 1994): 265–75. http://dx.doi.org/10.1016/0168-1656(94)90133-3.

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Ruohomäki, Timo, Andreas Andra, and Kimmo Raivio. "Defining Data-Driven Analytical Methods on Improving Energy-Efficiency in Apartment Buildings." Engineering Proceedings 2, no. 1 (November 14, 2020): 68. http://dx.doi.org/10.3390/ecsa-7-08209.

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Energy efficiency is one of the key characteristics of smart cities and data-driven analytical methods, especially including Internet of Things (IoT) sensors, and meaningful indicators are provided to support initiatives but also changing behavior at the citizen level. The analysis is often undertaken in closed systems that contain sensors, data acquisition, analysis and visualization. To improve the effectiveness of energy-efficiency initiatives in climate programs, harmonization of analytical methods and quality assurance of the data are required. This paper provides an overview of these themes based on the findings from two European Union (EU)-funded projects, European Regional Development Fund (ERDF) 6Aika Climate Friendly Housing Companies and Horizon 2020 mySMARTLife.
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Nicola, Mihaylov. "Best Practices and Lessons Learned from the Project 15.3.1.017 „Risk Management for Large Scale Infrastructures in the Romanian-Bulgarian CrossBorder Area“." Scientific Bulletin of Naval Academy XIX, no. 1 (July 15, 2018): 550–54. http://dx.doi.org/10.21279/1454-864x-18-i1-082.

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The paper presents the main results from the implementation of the project 15.3.1.017 „Risk Management for Large Scale Infrastructures in the Romanian-Bulgarian Cross-Border Area“, financed by the European Regional Development Fund (ERDF) and the Programme Interreg V-A Romania – Bulgaria. The project includes a study of the main infrastructure objects from the chemical industry, energy and transport infrastructures. Documents have been developed in order to raise the awareness of the population in the crossborder region. The knowledge of the trainees has been assessed in respect to risk management and the information related to it. The paper presents a statistical analysis of the questionnaires completed during the project.
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Cipolla, Sara Simona, Margherita Altobelli, and Marco Maglionico. "Decentralized Water Management: Rainwater Harvesting, Greywater Reuse and Green Roofs within the GST4Water Project." Proceedings 2, no. 11 (July 30, 2018): 673. http://dx.doi.org/10.3390/proceedings2110673.

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this study proposes the results of a research activity devoted to the analysis and development of methodologies, models and strategies, which allow integrating decentralized solutions such as rainwater harvesting, greywater reuse systems, and green technologies in buildings. A methodology based on a hydraulic/hydrological model developed by means of SWMM is presented. It allows estimating the optimal size of the storage tanks, considering the overall efficiency of the system, and calculating the wastewater overflows reduction. This study is carried out within the Work Package three (WP3) of the GST4Water project funded by the Emilia-Romagna Regional Council (Italy) through the European Regional Development Fund 2014–2020 ERDF—ROP.
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Lo Piano, Samuele, Emanuele Borgonovo, Arnald Puy, Andrea Saltelli, John Walsh, and Daniele Vidoni. "Improving the reliability of cohesion policy databases." PLOS ONE 17, no. 4 (April 22, 2022): e0266823. http://dx.doi.org/10.1371/journal.pone.0266823.

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In this contribution, we present an innovative data-driven model to reconstruct a reliable temporal pattern for time-lagged statistical monetary figures. Our research cuts across several domains regarding the production of robust economic inferences and the bridging of top-down aggregated information from central databases with disaggregated information obtained from local sources or national statistical offices. Our test bed case study is the European Regional Development Fund (ERDF). The application we discuss deals with the reported time lag between the local expenditures of ERDF by beneficiaries in Italian regions and the corresponding payments reported in the European Commission database. Our model reconstructs the timing of these local expenditures by back-dating the observed European Commission reimbursements. The inferred estimates are then validated against the expenditures reported from the Italian National Managing Authorities (NMAs) in terms of cumulative monetary difference. The lower cumulative yearly distance of our modelled expenditures compared to the official European Commission payments confirms the robustness of our model. Using sensitivity analysis, we also analyse the relative importance of the modelling parameters on the cumulative distance between the modelled and reported expenditures. The parameters with the greatest influence on the uncertainty of this distance are the following: first, how the non-clearly regionalised expenditures are attributed to individual regions; and second, the number of backward years that the residuals of the yearly payments are spread onto. In general, the distance between the modelled and reported expenditures can be further reduced by fixing these parameters. However, the gain is only marginal for some regions. The present study paves the way for modelling exercises that are aimed at more reliable estimates of the expenditures on the ground by the ultimate beneficiaries of European funds. Additionally, the output databases can contribute to enhancing the reliability of econometric studies on the effectiveness of European Union (EU) funds.
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Sikora-Gaca, Małgorzata. "Implementation of the structural funds in the sector of arts and culture in Poland in 2007–2013." Studia Gdańskie. Wizje i rzeczywistość XIII (June 3, 2017): 125–43. http://dx.doi.org/10.5604/01.3001.0015.7126.

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The purpose of the following article is to analyze the implementation of structural funds in the arts and culture sector of in Poland in the years 2007 – 2013. The subject of the study consists of 980 contracted projects implemented in 2007 – 2013 in 16 provinces. We have selected only those that have been co-financed from the structural funds, namely the European Regional Development Fund (ERDF), from which 4.93 billion PLN funding had been acquired for the mentioned 980 projects. The largest number of investments was realized in the Silesian province – 135, and the least in the Lubusz – 10. The largest share in the disbursement of structural funds was in the Mazovian province – 797.2 million PLN.
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Turmo, Isabel González. "A methodology for analysing recipe books." Social Science Information 43, no. 4 (December 2004): 753–73. http://dx.doi.org/10.1177/0539018404047717.

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The methodology discussed in this article was developed for the ERDF (European Regional Development Fund)-funded project “Anthropology of Food: Cooking and Food Habits on Both Sides of the Straits of Gibraltar. Andalusia and Morocco, 19th-20th Centuries”. It aims to facilitate a comparative analysis of recipe books and a large quantity of recipes, taking into consideration all their various components. Two computer applications were developed for this purpose: “Índice” (Index) and “Recetas” (Recipes). The first of these permits a comparative analysis of the ingredients, condiments and main culinary techniques of 5000 recipes, whilst the second was used to undertake a more in-depth analysis of a series of recipes, grouped according to culinary typologies.
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Kühn, M. "The ECJ’s decision CCI de l’Indre: Risk of ERDF Recovery after Faulty Procurement Measures Increased." European Procurement & Public Private Partnership Law Review 7, no. 3 (2012): 191–94. http://dx.doi.org/10.21552/epppl/2012/3/146.

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Wanner, Alice, and Ulrike Pröbstl-Haider. "Barriers to Stakeholder Involvement in Sustainable Rural Tourism Development—Experiences from Southeast Europe." Sustainability 11, no. 12 (June 18, 2019): 3372. http://dx.doi.org/10.3390/su11123372.

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Participative planning approaches are vital to sustainable development in rural areas. However, stakeholder involvement also faces many barriers. In this Danube region case study, barriers to stakeholder involvement across eight rural regions are investigated. With the standardized conditions provided through an ERDF and IPA funded EU project, special attention could be paid to socio-cultural barriers, specifically concerning perception of sustainability and conflicts of interest. The effects of these barriers to the planning process are seen in the comparison of awareness concerning overall goals, indicators and the regional self-assessments. The implications for planning and management in rural tourism areas find that the perception of sustainability varies greatly, perceived deficiencies increase awareness and that crucial indicators need to be understood by stakeholders beginning a participative planning approach.
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Bevilacqua, Carmelina. "Research and Innovation Transfer in the Field of PPP Applied to Urban Regeneration Actions and Policies." Advanced Engineering Forum 11 (June 2014): 282–90. http://dx.doi.org/10.4028/www.scientific.net/aef.11.282.

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The European Union has recognized the centrality of community in economic development processes by stressing the role of the cities in delivering smart, sustainable and inclusive growth. The European Commission has recently published a study on how cities use ERDF to make their cities a better place to live and work [. One of the most engaging results of the study is the variable geometry of strategies in place to achieve urban and territorial cohesion through the implementation of integrated approaches. The area-based type of intervention dominates many of the practices, especially those in deprived areas, because of social, economic and environmental factors. Physical regeneration is still a major driver in creating multi-stakeholder cooperation in the integration of policies. There are relatively few cases in which the place-based approach was combined with a people-based approach and even fewer where ERDF and European Social Fund (ESF) cross-funding was developed [2]. Even the urban dimension in the EU cohesion policy is not a new issue, the way in which the Europe 2020 intends to ensure integrated approach in the sustainable urban development is quite new because it entails both thematic concentration and involvement of the community. According to the Commissions proposals, there are several ways to support sustainable urban development with the Structural Funds: Operational programmes, Integrated Territorial Investment (ITI), Community-Led Local Development, financial instruments (like Jessica and Jeremie) by enhancing new forms of Public Private Partnership. The paper reports some interesting findings of the CLUDs project with respect the role of no-profit organization in different forms of Public Private Partnerships used to regenerate urban districts in the Metropolitan Area of Boston. The research funded by IRSES Marie Curie Actions has created an international network of 4 EU universities (Reggio Calabria, Rome, Salford and Helsinki) and 2 US universities (Northeastern University of Boston and San Diego State University) in research and innovation transfer in the field of PPP applied to urban regeneration actions and policies.
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Abelite, Larisa, Diana Zagulova, Llona Skuja, and Alena Jakub. "Participation of Teachers and MA Students in the Study of Various Aspects of the Activity Level of Riga’s Residents in Solving Problems in Their Neighbourhoods." SOCIETY, INTEGRATION, EDUCATION. Proceedings of the International Scientific Conference 1 (May 30, 2015): 13. http://dx.doi.org/10.17770/sie2013vol1.148.

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The article is devoted to the research work in the ERDF INTERREG IVA project CB5 "Creating attractive and dynamic society together with inhabitants" (CADDIES). The aim of the research work is to generalize the survey results of citizens in Latvia (Riga) for defining of social and economical factors, influencing social identity, place attachment and sense of community and for marking out the distinguishing features of mentioned above phenomenon for citizens from Latvia. The objects of investigation are practical aspects of social identity, place attachment and sense of community for citizens in Latvia. Sociological survey had been used. In general, there are mentioned all local actors to be important for being involved in neighbourhood development. Some aspects of citizens’ life were studied and the most effective involving methods were suggested for their participation in life improvement.
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Ricci, C., T. T. Ananna, M. J. Temple, C. M. Urry, M. J. Koss, B. Trakhtenbrot, Y. Ueda, et al. "BASS XXXVII: The Role of Radiative Feedback in the Growth and Obscuration Properties of Nearby Supermassive Black Holes." Astrophysical Journal 938, no. 1 (October 1, 2022): 67. http://dx.doi.org/10.3847/1538-4357/ac8e67.

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Abstract We study the relation between obscuration and supermassive black hole (SMBH) accretion using a large sample of hard X-ray selected active galactic nuclei (AGNs). We find a strong decrease in the fraction of obscured sources above the Eddington limit for dusty gas ( log λ Edd ≳ − 2 ) confirming earlier results, and consistent with the radiation-regulated unification model. This also explains the difference in the Eddington ratio distribution functions (ERDFs) of type 1 and type 2 AGNs obtained by a recent study. The break in the ERDF of nearby AGNs is at log λ Edd * = − 1.34 ± 0.07 . This corresponds to the λ Edd where AGNs transition from having most of their sky covered by obscuring material to being mostly devoid of absorbing material. A similar trend is observed for the luminosity function, which implies that most of the SMBH growth in the local universe happens when the AGN is covered by a large reservoir of gas and dust. These results could be explained with a radiation-regulated growth model, in which AGNs move in the N H–λ Edd plane during their life cycle. The growth episode starts with the AGN mostly unobscured and accreting at low λ Edd. As the SMBH is further fueled, λ Edd, N H and the covering factor increase, leading the AGN to be preferentially observed as obscured. Once λ Edd reaches the Eddington limit for dusty gas, the covering factor and N H rapidly decrease, leading the AGN to be typically observed as unobscured. As the remaining fuel is depleted, the SMBH goes back into a quiescent phase.
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Jeannerod-Dumouchel, Nathalie. "One generation may hide another : Generation Y or new socialization tactics ? Past and Present at ERDF." Revue de gestion des ressources humaines 102, no. 4 (2016): 74. http://dx.doi.org/10.3917/grhu.102.0074.

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Pușcaș, Andreea, and Ioana Beleiu. "The mechanism of community led local development in Romanian urban areas." Virgil Madgearu Review of Economic Studies and Research 13, no. 2 (November 23, 2020): 129–46. http://dx.doi.org/10.24193/rvm.2020.13.65.

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Community led local development (CLLD) is a tool of the European Commission, used for territorial development. Local Action Groups were funded in the rural areas of Romania, since the 2007-2013 programming period through LEADER, demonstrating positive effects in terms of social innovation and disproof of social disparities. In urban areas, CLLD is a recent multi-fund approach, financed by the European Social Fund (ESF) and the European Regional Development Fund (ERDF). Despite the intentions addressed for simplifying the implementation of the mechanism by the Romanian authorities, several challenges and delays however occurred. The present research reveals the similarities and the main differences between the implementation of the mechanism, in urban and rural areasesides, it proposes a set of recommendations to increase the efficiency of the studied mechanism, based on a case study on the implementation of the CLLD mechanism in Gherla, Romania.
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Szabó, Mariann, and Fruzsina Bozsoki. "Redevelopment of Brownfields for Cultural Use from ERDF Fund—The Case of Hungary between 2014 and 2020." Journal of Risk and Financial Management 15, no. 4 (April 14, 2022): 181. http://dx.doi.org/10.3390/jrfm15040181.

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In the current research we aim to analyse the public redevelopment projects financed in Hungary from the Territorial and Settlement Development OP between 2014 and 2020, with special focus on cultural use. Brownfield redevelopment is a major topic in an urban development context from an urban sustainability, circularity, and creative urban/regional development point of view. Within the examined period, 39% of the brownfield redevelopment projects have cultural ties. A detailed introduction of the cases highlights the importance of landscape-oriented spatial strategies, temporary use, and mixed land use options in redevelopment for long-term viability. The original function of redevelopment projects encompasses a wide range. We could find industrial brownfields from the 19th century to agro-food facilities from the soviet era, which proves that the allocation of ERDF funds for brownfield redevelopments helped the rehabilitation of those sites which are important in showcasing Hungarian history.
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Ferasso, Marcos, Miguel Blanco, and Lydia Bares. "Territorial Analysis of the European Rural Development Funds (ERDF) as a Driving Factor of Ecological Agricultural Production." Agriculture 11, no. 10 (October 3, 2021): 964. http://dx.doi.org/10.3390/agriculture11100964.

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The Europe 2030 project identified the need to create a growth model that is based on a dynamic balance between economic, social, and environmental dimensions. This involves, among other objectives, redirecting the resources that are allocated to the Common Agricultural Plan (CAP) toward more ecological agriculture and livestock. In recent decades, two packages of the European Agricultural Fund for Rural Development (EAFRD) approved funds for projects related to agriculture. This study carried out a regional evaluation of the effects on production and employment that were generated in the Spanish organic farming sector. For this, a methodology that is frequently used by researchers to analyze territorial differences was used, namely, the shift-share analysis. The main results showed important differences at the regional level in the production of crops. Likewise, constant shift and constant share analyses were used to forecast the evolution of the sector from the recent data. Pending the approval of the new EAFRD 2021–2030, the results obtained in this research allowed for the identification of the regions that showed a favorable evolution to change the agricultural model and to identify the projects that generated employment and ecological production in the sector.
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Bielicka, Małgorzata, and Magdalena Olpińska-Szkiełko. "Nauczanie języka sąsiada od przedszkola do zakończenia edukacji – kluczem do komunikacji w Euroregionie Pomerania. Założenia teoretyczne, cele i wstępne wyniki projektu." Neofilolog, no. 58/1 (April 27, 2022): 119–32. http://dx.doi.org/10.14746/n.2022.58.1.8.

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The paper presents a report on the implementation of the educational project Teaching the neighbours’ language from kindergarten to the end of education - the key to communication in the Euroregion Pomerania co-financed by the European Regional Development Fund (ERDF) under the Interreg VA Cooperation Program Mecklenburg-Vorpommern/Brandenburg/Poland. 24 educational institutions in Poland and 33 educational institutions in Germany took part in the project. 3,771 children and 821 teachers and kindergarten educators participated in project events. The number of lessons conducted during the project was over 30,000. In addition to school education, the project covered numerous meetings of Polish and German children and youth, workshops for teachers, educational forums for parents and others. The project developed curricula for German as a language of the neighbours at all educational stages and in all types of Polish schools, as well as numerous multimedia teaching materials, such as educational games, worksheets, educational films, etc. This paper describes the project, its theoretical and practical foundations and its results.
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Giordano, Benito. "Exploring the role of the ERDF in regions with specific geographical features: islands, mountainous and sparsely populated areas." Regional Studies 51, no. 6 (August 12, 2016): 869–79. http://dx.doi.org/10.1080/00343404.2016.1197387.

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Giordano, Benito, and Alexandre Dubois. "Combining territory and competitiveness in EU Regional Policy? Analyzing ERDF investment profiles in regions with specific geographical features." Regional Studies 53, no. 8 (August 1, 2018): 1221–30. http://dx.doi.org/10.1080/00343404.2018.1495323.

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40

Dratwa, A. "Atrial Natriuretic Peptide and Renal Haemodynamics in Newborn Calves." Acta Veterinaria Brno 75, no. 4 (2006): 477–83. http://dx.doi.org/10.2754/avb200675040477.

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The study was aimed to provide information on the dynamics of changes in the concentration of ANP in blood plasma of calves during the first seven days of their life and to find any association between blood plasma ANP concentration and effective renal blood (ERBF) and plasma flow (ERPF) and glomerular filtration rate (GFR). The experiment was carried out on 10 clinically healthy Black and White calves during the first seven days of postnatal life. The concentration of atrial natriuretic peptide (ANP) in blood plasma was determined with radioimmunoassay. The kidney function was assessed by clearance methods, using para-aminohippuric acid and inulin. The blood plasma ANP concentration increased with age. On the first day the mean concentration of ANP was 5.72 ± 1.34 pmol/l, on the 7th day it was 14.34 ± 2.09 pmol/l. The ERBF and ERPF during the first week of life showed variations, mean ERBF ranging within 280.22 ± 10.30 ml/min/m2 (1st day) and 338.25 ± 13.72 ml/min/m2 (7th day) and ERPF ranging between 179.77 ± 8.27 ml/min/m2 (1st day) and 245.22 ± 9.86 ml/min/m2 (7th day). The mean GFR on the first day was 35.68 ± 2.10 ml/min/m2 and significantly (p < 0.01) increased on the second day 49.97 ± 1.76 ml/min/m2, subsequently GFR remained on a stabile level average 51.06 ml/min/m2. The studies showed no correlations between plasma ANP concentration and ERPF (ERBF) and GFR. These data indicate that in calves during the first seven days of postnatal life endogenous ANP did not change the effective renal blood (plasma) flow and glomerular filtration rate.
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Butkus, Mindaugas, Alma Mačiulytė-Šniukienė, Kristina Matuzevičiutė, and Diana Cibulskienė. "Does Financial Support from ERDF and CF Contribute to Convergence in the EU? Empirical Evidence at NUTS 3 Level." Prague Economic Papers 29, no. 3 (June 16, 2020): 315–29. http://dx.doi.org/10.18267/j.pep.737.

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42

Mulu, Hundera, Geert Duysters, Wim Naudé, and Josette Dijkhuizen. "The conflict between social role expectations and entrepreneurial role demands among women entrepreneurs in sub-Saharan Africa: empirical study from Ethiopia." Gender in Management: An International Journal 36, no. 3 (March 8, 2021): 430–48. http://dx.doi.org/10.1108/gm-08-2019-0141.

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Purpose The purpose of this paper is to develop items for measuring the role conflict between social role expectations (SREs) and entrepreneurial role demands (ERDs) among women entrepreneurs in sub-Saharan Africa (SSA). Design/methodology/approach This paper uses 20 interviews and literature from SSA to develop items, a survey of 408 to conduct factor analysis and a survey of 307 to conduct criterion validity analysis. Findings Statistical analysis shows that the scales used adequately captured two dimensions of SRE and ERD conflict: SRE-to-ERD conflict and ERD-to-SRE conflict. It was found that the SRE-to-ERD-conflict scale is reliable and valid with the five dimensions of entrepreneurial success and that women entrepreneur’s experience significant role conflict between SREs and ERDs. Research limitations/implications The implication is that standard scales measuring work and family conflict, which tend to focus solely on the work and family context, cannot adequately account for role conflict among women entrepreneurs. Practical implications The practical implications of these findings are discussed. Originality/value New scale items form measuring the conflict between SREs and ERDs were developed.
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Zong, Ke, Yuan Yuan, Carlos Enrique Montenegro-Marin, and Seifedine Nimer Kadry. "Or-Based Intelligent Decision Support System for E-Commerce." Journal of Theoretical and Applied Electronic Commerce Research 16, no. 4 (March 26, 2021): 1150–64. http://dx.doi.org/10.3390/jtaer16040065.

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Aim: This paper aims to analyze, prepare, and review the general guidelines and rules that govern the development of key factors influencing the enhancement of emotionally supportive networks and selection models using fuzzy logic theory. The researchers have identified eight important components of the information society (IS), representing the computerized economy’s growth to explain a realistic framework for medium-term gauges and proposals. Materials and methods: A discrete-nonstop opportunity paradigm portrays the creation of the general framework, in which the mutual effects of each of the components are spoken to models within the state-space. The software’s mechanical quality offers improvement displayed along these lines that may indicate future interest to programing suppliers. The researchers have given supposed to the developments and interests of information technology (IT) professionals in R&D to provide insightful foundations. For example, this study will demonstrate the development of emotionally supportive networks and recommendations of choices for 3D-web-based businesses and their impact on mechanical advancement, examples of use and social behavior. Results: During an IS/IT foreknowledge undertaking completed in Poland in 2019 and sponsored by the Education Research and Development Foundation ERDF, the results were obtained.
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Korauš, Antonín, Miroslav Gombár, and Filip Černák. "Changes in the Structure of International Trade And Services in the Context of Tax Fraud and Tax Evasion." SHS Web of Conferences 126 (2021): 09001. http://dx.doi.org/10.1051/shsconf/202112609001.

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The EU and the Member States have been forced in recent years to take a stronger position against the growing trend of tax fraud, tax evasion, and tax avoidance. The EU legislative and non-legislative acts in this area have resulted from political attitudes, economic intentions, proposals, and compromises reached between the individual Member States, on the one hand, and the EU, on the other, in their effort to combat fraudulent behaviour in the taxation area. The fight against fraudulent behaviour in the taxation area, be it tax fraud, tax evasion or tax avoidance, has become a real global challenge not only for the EU and its Member States but also for the entire world. These are different forms and methods for misusing tax systems both within the EU and abroad. This paper is part of the project: “Electronic methods for detecting unusual business transactions in the business environment” (ITMS code: 313022W057), co-financed by the European Regional Development Fund (ERDF) and also the project “VEGA1 / 0194/19 — Research on process-oriented financial management with a focus on to detect tax evasion in international trade”.
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Gatto, Fabiana, Sara Daniotti, and Ilaria Re. "Driving Green Investments by Measuring Innovation Impacts. Multi-Criteria Decision Analysis for Regional Bioeconomy Growth." Sustainability 13, no. 21 (October 23, 2021): 11709. http://dx.doi.org/10.3390/su132111709.

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Regional policies play a pivotal role in green transition and pursuing the European Green Deal decarbonization targets. Despite the general recognition of the strategic value of the bioeconomy in realizing this challenge, regional roadmaps for its growth are not yet a widespread tool in local innovation policy. Conversely, driving green investments by measuring the innovation potential of the bioeconomy could shape a low-carbon economy by leveraging the full potential of local resources. In order to validate a replicable decision-making model driving 2021–2027 ERDF funds towards this mission, this paper measures the economic, social and technological impact of the Lombard bioeconomy through five applications and eight criteria. The methodology allows quantification of the local bioeconomy value and, through a Multi-Criteria Decision Analysis (MCDA), identifies the bio-based applications with the highest innovation potential. By measuring the current and prospective impact of the bioeconomy, Bio-chemicals, Agri-foods, and Biopolymers emerges as the applications with the highest innovation potential rate for Lombardy. Five recommendations to drive green investments and shape the regional roadmap for the bioeconomy are finally defined, providing a tool for industrial applications with a greater impact on local competitiveness.
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Grazi, Laura. "Origini e sfide della politica regionale comunitaria: dagli studi preliminari all'Atto unico europeo (1957-1986)." MEMORIA E RICERCA, no. 30 (July 2009): 47–57. http://dx.doi.org/10.3280/mer2009-030005.

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- The article describes the different stages which marked the elaboration of the EEC regional policy starting from the preliminary studies in the Sixties to the formal inclusion of this domain in the Single European Act (1986). The creation of the European Regional Development Fund (1975) and its reforms are crucial events in the definition of the EEC regional policy which highlight the slow and difficult passage from a system redistributing money among Member States to the launch of new form of supranational territorial solidarity. The ERDF, that was initially linked to the need to rearrange the financial benefits of membership/accession to the EEC for some members States (in particular, Italy and Great Britain), was later rearranged in order to allow more autonomous policy choices at the Community level (Community programmes). The Integrated Mediterranean Programmes, adopted in the Eighties, are the symbol of this new approach because they linked EEC regional measures to common problems arising from economic integration and increased the coordinating functions of the Commission.Parole chiave: Politica regionale della CEE, Commissione europea, Economie regionali, FESR, Programmi comunitari, PIM EEC Regional Policy; European Commission, Regional Economies, European Regional Development Fund, Community Programmes, Integrated Mediterranean Programmes
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Halme, Juha. "The role of social capital in the institutionalization of regional place marketing activity." Place Branding and Public Diplomacy 17, no. 3 (March 1, 2021): 249–56. http://dx.doi.org/10.1057/s41254-021-00201-x.

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AbstractThis paper aims to study the outcomes of the regional level place marketing projects, which contribute towards the fruition of long-term place marketing or branding goals. It applies a theoretical framework based on institutional and social capital theories. Hence, it highlights the role of networks, norms of behavior and values, and trust regarding the institutionalization of regional place marketing activity. Two ERDF (European Structural Development Funding)-funded regional place marketing projects carried out in eastern Finland are explored. The empirical material consists of 23 semi-structured interviews of steering group members of the projects and documentary data on the later developments of the place marketing activity in the regions. The findings show that social capital generated during the projects contributed to the institutionalization of place marketing activity by reinforcing the will to do place marketing together, forming information-sharing practices, and expanding and strengthening stakeholder networks. Results indicate that social relations and structures that are formed during the place marketing collaborations can extend the lifespan of regional place marketing activity beyond short-lived projects, while there remains a need to develop this perspective into a measurable variable.
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BACHTLER, JOHN, and IAIN BEGG. "Cohesion policy after Brexit: the economic, social and institutional challenges." Journal of Social Policy 46, no. 4 (July 18, 2017): 745–63. http://dx.doi.org/10.1017/s0047279417000514.

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AbstractSince 1988, when the current EU Cohesion Policy was introduced, it has played an influential role in setting priorities for policies aimed at dealing with the effects of European economic integration on regional and social disparities. Although, latterly, the amount of money spent in the UK through the European Structural and Investment Funds (ESIF) has declined, EU programmes have had a disproportionate effect on the design and implementation of UK policies shaping regional and local economic and social development. This paper starts by recalling how EU Cohesion Policy has functioned in the UK, then considers how Brexit may affect regional and social development and the need for a corresponding policy response, focusing on the sorts of policies currently supported by the European Regional Development Fund (ERDF) and the European Social Fund (ESF). The paper shows that filling the policy vacuum will be far from straightforward because complementary national policies and institutional frameworks have lacked consistency or coherence. It concludes by examining the wider policy issues arising from rethinking domestic policy outside the ESIF framework. The sub-national level, in particular, will need a fresh approach following Brexit.
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Remuzgo Martinez, S., F. Genre, V. Pulito-Cueto, D. Prieto-Peña, B. Atienza-Mateo, B. Sevilla, J. Llorca, et al. "AB0012 ROLE OF IRF5 GENE ON THE PATHOGENESIS OF IMMUNOGLOBULIN-A VASCULITIS." Annals of the Rheumatic Diseases 79, Suppl 1 (June 2020): 1309.1–1310. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1023.

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Background:Interferon signaling pathway plays a relevant role in autoimmunity. Genetic variants in theinterferon regulatory factor (IRF) 5gene, that encodes the major regulator of the type I interferon induction [1], have been related to the development of several inflammatory diseases [2].Objectives:To determine the influence ofIRF5on Immunoglobulin-A vasculitis (IgAV), an inflammatory vascular disease.Methods:ThreeIRF5polymorphisms (rs2004640, rs2070197 and rs10954213) representative of 3 different haplotype blocks were genotyped in 372 Caucasian patients with IgAV and 876 sex and ethnically matched healthy controls.Results:No statistically significant differences between patients with IgAV and controls were observed when eachIRF5polymorphism was analyzed independently. Similarly, no statistically significant differences between patients with IgAV and controls were found whenIRF5polymorphisms were evaluated combined conforming haplotypes. Additionally, there were no statistically significant differences in genotype, allele and haplotype frequencies ofIRF5when patients with IgAV were stratified according to the age at disease onset or to the presence/absence of gastrointestinal or renal manifestations.Conclusion:Our results do not support an influence ofIRF5on the pathogenesis of IgAV.References:[1]Nat Immunol 2011; 12: 231-8;[2]Arthritis Res Ther 2014; 16: R146.Acknowledgments:This study was supported by European Union FEDER funds and “Fondo de Investigaciones Sanitarias” (grant PI18/00042) from ‘Instituto de Salud Carlos III’ (ISCIII, Health Ministry, Spain). RL-M is a recipient of a Miguel Servet type I programme fellowship from the ISCIII, co-funded by the European Social Fund (ESF, `Investing in your future´) (grant CP16/00033). SR-M is supported by funds of the RETICS Program (RD16/0012/0009) (ISCIII, co-funded by the European Regional Development Fund (ERDF)). VP-C is supported by a pre-doctoral grant from IDIVAL (PREVAL 18/01). LL-G is supported by funds of PI18/00042 (ISCIII, co-funded by ERDF).Disclosure of Interests:Sara Remuzgo Martinez: None declared, Fernanda Genre: None declared, Verónica Pulito-Cueto: None declared, D. Prieto-Peña: None declared, Belén Atienza-Mateo: None declared, Belén Sevilla: None declared, Javier Llorca: None declared, Norberto Ortego: None declared, Leticia Lera-Gómez: None declared, Maite Leonardo: None declared, Ana Peñalba: None declared, María Jesús Cabero: None declared, Luis Martín-Penagos: None declared, Jose Alberto Miranda-Filloy: None declared, Antonio Navas Parejo: None declared, Javier Sanchez Perez: None declared, Maximiliano Aragües: None declared, Esteban Rubio: None declared, MANUEL LEON LUQUE: None declared, Juan María Blanco-Madrigal: None declared, E. Galindez: None declared, Javier Martin Ibanez: None declared, Santos Castañeda: None declared, Ricardo Blanco Grant/research support from: Abbvie, MSD and Roche, Consultant of: Abbvie, Pfizer, Roche, Bristol-Myers, Janssen and MSD, Speakers bureau: Abbvie, Pfizer, Roche, Bristol-Myers, Janssen, Lilly and MSD, Miguel A González-Gay Grant/research support from: Pfizer, Abbvie, MSD, Speakers bureau: Pfizer, Abbvie, MSD, Raquel López-Mejías: None declared
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Genre, F., S. Remuzgo Martinez, V. Pulito-Cueto, D. Prieto-Peña, B. Atienza-Mateo, B. Sevilla, J. Llorca, et al. "AB0011 INFLUENCE OF IL17A GENE ON THE PATHOGENESIS OF IMMUNOGLOBULIN-A VASCULITIS." Annals of the Rheumatic Diseases 79, Suppl 1 (June 2020): 1309.2–1309. http://dx.doi.org/10.1136/annrheumdis-2020-eular.641.

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Background:Cytokines signaling pathway genes represent a key component of the genetic network implicated in the pathogenesis of Immunoglobulin-A vasculitis (IgAV) [1], an inflammatory vascular pathology.Interleukin (IL)17Ais a genetic risklocusfor autoimmune diseases, such as giant cell arteritis [2] and spondyloarthritis [3].Objectives:To determine the potential influence ofIL17Aon IgAV.Methods:FiveIL17Atag polymorphisms (rs4711998, rs8193036, rs3819024, rs2275913 and rs7747909) were genotyped in 360 Caucasian patients with IgAV and 1,003 sex and ethnically matched healthy controls.Results:No statistically significant differences between patients with IgAV and healthy controls were observed when eachIL17Agenetic variant was analyzed independently. Similarly, no statistically significant differences between patients with IgAV and healthy controls were found when the fiveIL17Apolymorphisms were evaluated combined conforming haplotypes. In addition, there were no statistically significant differences in genotype, allele and haplotype frequencies ofIL17Awhen patients with IgAV were stratified according to the age at disease onset or to the presence/absence of gastrointestinal or renal manifestations.Conclusion:Our results do not support an influence ofIL17Aon the pathogenesis of IgAV.References:[1]Autoimmun Rev 2018; 17: 301-15[2]Ann Rheum Dis 2014; 73: 1742-5[3]Mediators Inflamm 2018; 2018: 1395823.Acknowledgments:This study was supported by European Union FEDER funds and “Fondo de Investigaciones Sanitarias” (grant PI18/00042) from ‘Instituto de Salud Carlos III’ (ISCIII, Health Ministry, Spain). RL-M is a recipient of a Miguel Servet type I programme fellowship from the ISCIII, co-funded by the European Social Fund (ESF, `Investing in your future´) (grant CP16/00033). SR-M is supported by funds of the RETICS Program (RD16/0012/0009) (ISCIII, co-funded by the European Regional Development Fund (ERDF)). VP-C is supported by a pre-doctoral grant from IDIVAL (PREVAL 18/01). LL-G is supported by funds of PI18/00042 (ISCIII, co-funded by ERDF).Disclosure of Interests:Fernanda Genre: None declared, Sara Remuzgo Martinez: None declared, Verónica Pulito-Cueto: None declared, D. Prieto-Peña: None declared, Belén Atienza-Mateo: None declared, Belén Sevilla: None declared, Javier Llorca: None declared, Norberto Ortego: None declared, Leticia Lera-Gómez: None declared, Maite Leonardo: None declared, Ana Peñalba: None declared, María Jesús Cabero: None declared, Luis Martín-Penagos: None declared, Jose Alberto Miranda-Filloy: None declared, Antonio Navas Parejo: None declared, Diego de Argila: None declared, Maximiliano Aragües: None declared, Esteban Rubio-Romero: None declared, MANUEL LEON LUQUE: None declared, Juan María Blanco-Madrigal: None declared, E. Galindez: None declared, Javier Martin Ibanez: None declared, Santos Castañeda: None declared, Ricardo Blanco Grant/research support from: Abbvie, MSD and Roche, Consultant of: Abbvie, Pfizer, Roche, Bristol-Myers, Janssen and MSD, Speakers bureau: Abbvie, Pfizer, Roche, Bristol-Myers, Janssen, Lilly and MSD, Miguel A González-Gay Grant/research support from: Pfizer, Abbvie, MSD, Speakers bureau: Pfizer, Abbvie, MSD, Raquel López-Mejías: None declared
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