Journal articles: 'Escherichai coli infections'

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Ramilo, Octavio, Windy Allman, Wendy Chung, Asuncion Mejias, Monica Ardura, Casey Glaser, Knut M. Wittkowski, et al. "Gene expression patterns in blood leukocytes discriminate patients with acute infections." Blood 109, no. 5 (November 14, 2006): 2066–77. http://dx.doi.org/10.1182/blood-2006-02-002477.

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Abstract Each infectious agent represents a unique combination of pathogen-associated molecular patterns that interact with specific pattern-recognition receptors expressed on immune cells. Therefore, we surmised that the blood immune cells of individuals with different infections might bear discriminative transcriptional signatures. Gene expression profiles were obtained for 131 peripheral blood samples from pediatric patients with acute infections caused by influenza A virus, Gram-negative (Escherichia coli) or Gram-positive (Staphylococcus aureus and Streptococcus pneumoniae) bacteria. Thirty-five genes were identified that best discriminate patients with influenza A virus infection from patients with either E coli or S pneumoniae infection. These genes classified with 95% accuracy (35 of 37 samples) an independent set of patients with either influenza A, E coli, or S pneumoniae infection. A different signature discriminated patients with E coli versus S aureus infections with 85% accuracy (34 of 40). Furthermore, distinctive gene expression patterns were observed in patients presenting with respiratory infections of different etiologies. Thus, microarray analyses of patient peripheral blood leukocytes might assist in the differential diagnosis of infectious diseases.

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Szymankiewicz, Maria, Krzysztof Koper, Konrad Dziobek, Zbigniew Kojs, and Lukasz Wicherek. "Microbiological monitoring in patients with advanced ovarian cancer before and after cytoreductive surgery – a preliminary report." Current Issues in Pharmacy and Medical Sciences 30, no. 4 (December 1, 2017): 198–202. http://dx.doi.org/10.1515/cipms-2017-0038.

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Abstract Multidrug-resistant organisms (MDROs) are becoming an increasing problem in hospitals. It is believed that screening patients for the incidence of MDROs prior to hospital admission not only allows for the proper management of infection following medical procedures, but can also potentially reduce the transmission of these bacteria to other patients. The aim of this study was to assess the carriers of selected MDROs in the gastrointestinal tract among patients with advanced ovarian cancer admitted to the hospital for cytoreductive surgery and to estimate the possible relationship between rectal colonization with these organisms and nosocomial infections. From December 2013 to May 2014, we evaluated the colonization with VRE (vancomycin-resistant Enterococcus), E. coli KPC+ (class A carbapenemase producing Escherichia coli), E. coli MBL+ (class B carbapenemase, metallo-ß lactamase producing Escherichia coli), and E. coli ESBL+ (extended-spectrum ß-lactamase producing Escherichia coli) in 42 patients. The patients were divided into two subgroups corresponding to the extent of their surgery: the first subgroup consisted of patients with large bowel resection (n=18) and the second subgroup of patients without resection (n=24). A rectal swab was taken within 24 hours of admission. Perioperative infectious complications were analyzed for the first 90 days following surgery with regard to the type of infection and the occurrence of examined MDROs. In our study, 2.4 % of all patients (23.8/1,000 hospitalizations) were colonized with ESBL - producing Escherichia coli: 0.0 % in the first subgroup and 4.2% in the second subgroup, respectively. We did not identify any patients who were colonized with VRE, E. coli MBL+, or E. coli KPC+. Surgical site infections were seen in 8 (19.1%) out of 42 patients. We were, therefore, unable to confirm a relationship between MDROs colonizing the large bowel and the etiological agents of perioperative infections. However, despite the lack of identification of MDROs as etiological agents of postoperative infection, the risk of serious infectious complications, combined with the changing epidemiological situation, means that microbiological monitoring should be performed in patients with ovarian cancer before and after cytoreductive surgery.

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FELIX DO NASCIMENTO SÉRGIO, VANESSA, EDUARDO RIBEIRO ALMEIDA DE CASTRO, CLAUDIA PATRÍCIA ALBUQUERQUE DE CARVALHO SERAPHIM, JOSÉ AUGUSTO ADLER PEREIRA, and ANTÔNIO PONCE DE LEON. "FATORES ASSOCIADOS À RESISTÊNCIA A ANTIMICROBIANOS DE ESCHERICHIA COLI CAUSADORAS DE INFECÇÕES DO TRATO URINÁRIO." Revista SODEBRAS 14, no. 167 (November 2019): 46–59. http://dx.doi.org/10.29367/issn.1809-3957.14.2019.167.46.

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Mazurek-Popczyk, Justyna, Justyna Pisarska, Ewa Bok, and Katarzyna Baldy-Chudzik. "Antibacterial Activity of Bacteriocinogenic Commensal Escherichia coli against Zoonotic Strains Resistant and Sensitive to Antibiotics." Antibiotics 9, no. 7 (July 15, 2020): 411. http://dx.doi.org/10.3390/antibiotics9070411.

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Antibiotic resistance concerns various areas with high consumption of antibiotics, including husbandry. Resistant strains are transmitted to humans from livestock and agricultural products via the food chain and may pose a health risk. The commensal microbiota protects against the invasion of environmental strains by secretion of bacteriocins, among other mechanisms. The present study aims to characterize the bactericidal potential of bacteriocinogenic Escherichia coli from healthy humans against multidrug-resistant and antibiotic-sensitive strains from pigs and cattle. Bacteriocin production was tested by the double-layer plate method, and bacteriocin genes were identified by the PCR method. At least one bacteriocinogenic E. coli was detected in the fecal samples of 55% of tested individuals, adults and children. Among all isolates (n = 210), 37.1% were bacteriocinogenic and contained genes of colicin (Col) Ib, ColE1, microcin (Mcc) H47, ColIa, ColM, MccV, ColK, ColB, and single ColE2 and ColE7. Twenty-five E. coli carrying various sets of bacteriocin genes were further characterized and tested for their activity against zoonotic strains (n = 60). Strains with ColE7 (88%), ColE1-ColIa-ColK-MccH47 (85%), MccH47-MccV (85%), ColE1-ColIa-ColM (82%), ColE1 (75%), ColM (67%), and ColK (65%) were most active against zoonotic strains. Statistically significant differences in activity toward antibiotic-resistant strains were shown by commensal E. coli carrying MccV, ColK-MccV, and ColIb-ColK. The study demonstrates that bacteriocinogenic commensal E. coli exerts antagonistic activity against zoonotic strains and may constitute a defense line against multidrug-resistant strains.

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Kakou Yao, Rita, Jules Abodou Tenon, and Akoun Abou. "Bioactive molecules modelised by numerical simulation:molecules against Escherichia Coli." Acta Crystallographica Section A Foundations and Advances 70, a1 (August 5, 2014): C1008. http://dx.doi.org/10.1107/s2053273314089918.

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The work exposed in this paper joins in the research of medecine by means of the modelling by digital simulation (method in silico). This method allows to plan the biological activities of new molecules and to design others more active than existing molecules against a given infection . The generated and validated models are used here in the research for molecules potentially more active against Escherichia coli which causes diarrheic infections at the human beings. Here, we report works the synthesis of our works of structural determination, of forecast of biological activity and conception of molecules bioactive again Eschericha coli.

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Drinan, Lorraine. "Escherichia coli infections." Nursing Standard 25, no. 8 (October 27, 2010): 59–60. http://dx.doi.org/10.7748/ns.25.8.59.s50.

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Makvana, S., and L. R. Krilov. "Escherichia coli Infections." Pediatrics in Review 36, no. 4 (April 1, 2015): 167–71. http://dx.doi.org/10.1542/pir.36-4-167.

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Preveden, Tomislav. "Bacterial infections in patients with liver cirrhosis." Medical review 68, no. 5-6 (2015): 187–91. http://dx.doi.org/10.2298/mpns1506187p.

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Introduction. Liver cirrhosis is characterized by a reduced defensive reaction to bacterial infections and patients with cirrhosis are at increased risk of developing infections, sepsis and death. The most common bacterial infections in these patients are spontaneous bacterial peritonitis, urinary tract infection, pneumonia, skin and soft tissue infection and bacteremia. The most common causes are Gram negative bacteria. The aim of this study was to determine the prevalence, localization and etiology of bacterial infections in hospitalized patients with liver cirrhosis. Material and Methods. This retrospective study included 401 patients with liver cirrhosis hospitalized at the Department of Infectious Diseases, Clinical Center of Vojvodina Novi Sad in the period from 2006 to 2010. Bacterial infection was diagnosed according to clinical examination, laboratory findings, radiological examination and bacterial positive culture. Results. The prevalence of bacterial infection was 38.15% (153/401). The most common infections were pneumonia (21.56%), urinary tract infection (20.91%), and spontaneous bacterial peritonitis (18.95%). Localization of infection remained undetermined in as many as 37 patients (24.18%). Bacterial cultures were positive in 32 patients (20.91%), Gram negative bacteria were commonly isolated, mostly Escherichia coli (71.87%). The mortality rate among patients with bacterial infections was 31.37% (48/153). Conclusion. Bacterial infections are often found in patients with liver cirrhosis, the most frequent being pneumonia, urinary tract infection and spontaneous bacterial peritonitis. Gram negative bacteria, especially Escherichia coli were predominant in the etiology. The extent to which bacterial infections are taken into consideration in cases with liver cirrhosis is rather high; however, they are not proved etiologically to the satisfactory level.

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Ribić, Rosana, Tomislav Meštrović, Marijana Neuberg, and Goran Kozina. "Effective anti-adhesives of uropathogenic Escherichia coli." Acta Pharmaceutica 68, no. 1 (March 1, 2018): 1–18. http://dx.doi.org/10.2478/acph-2018-0004.

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Abstract Urinary tract infections (UTIs) caused by uropathogenic Escherichia coli (UPEC) are among the most common infectious diseases in humans. Due to their frequent occurrence in the community and nosocomial settings, as well as the development of resistance to the commonly prescribed antimicrobial agents, an enormous financial burden is placed on healthcare systems around the world. Therefore, novel approaches to the prevention and treatment of UTIs are needed. Although UPEC may harbour a plethora of virulence factors, type I fimbriae and P pili are two of the most studied adhesive organelles, since the attachment to host cells in the urinary tract is a crucial step towards infection. Design of receptor analogues that competitively bind to UPEC surface adhesins placed at the top of pili organelles led to the development of anti-adhesive drugs that are increasingly recognized as important and promising alternatives to antibiotic treatment of UTIs.

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Schousboe, Mona, Jania Lynds, and Chris Ambrose. "Increased Incidence of Escherichia Coli Bacteremia Post-Christchurch Earthquake 2011: Possible Associations." Prehospital and Disaster Medicine 28, no. 3 (February 21, 2013): 202–9. http://dx.doi.org/10.1017/s1049023x13000137.

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AbstractIntroductionEarthquakes are natural events that contribute to the transmission of infectious diseases. The aim of this research was to determine whether the observed increase in Escherichia coli (E. coli) bloodstream infections (BSI) during the period March-June 2011 was associated with the February 2011 Christchurch earthquake.MethodsDescriptive statistics and spatial distributional analysis techniques were used to quantify patients with E. coli BSI in 2009-2011.ResultsE. coli BSI acquired from non-catheter related urinary tract infection (UTI) was the predominant infection type, with the greatest increase during March-June 2011. Bacteremia incidence was higher in females than in males for 2009-2011. In 2011, the median age of patients was 75 years, and an increase in males acquiring such infections was noted. Spatial distributional analysis failed to show direct association between bacteremia cases and liquefaction-related land damage or drinking water contamination. A higher incidence of E. coli BSI post-earthquake in the eastern suburbs, which tend towards a higher level of socioeconomic deprivation, was observed.ConclusionA number of possible factors contributing to the observed increase in E. coli BSI acquired from UTI in 2011 were considered. Individuals with higher deprivation indices, males and the elderly may be particularly vulnerable to the effects of a major disaster with subsequent breakdown of infrastructure. These findings have important implications in natural disaster situations, and justify development of strategies to identify UTI and pyelonephritis risk factors and to manage E. coli bacteremia incidence rates.SchousboeM, LyndsJ, AmbroseC. Increased incidence of Escherichia Coli bacteremia post-Christchurch earthquake 2011: possible associations. Prehosp Disaster Med. 2013;28(3):1-8.

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Honish, L., N. Punja, S. Nunn, D. Nelson, N. Hislop, G. Gosselin, N. Stashko, and Stashko Stashko. "Infections à Escherichia coli O157:H7 associées à des produits de viande de porc contaminés - Alberta (Canada), de juillet à octobre 2014." Relevé des maladies transmissibles au Canada 43, no. 1 (January 5, 2017): 23–26. http://dx.doi.org/10.14745/ccdr.v43i01a04f.

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Ziese, T., Y. Anderson, B. de Jong, S. Löfdahl, and M. Ramberg. "Outbreak of Escherichia coli O157 in Sweden." Eurosurveillance 1, no. 1 (January 1, 1996): 2–3. http://dx.doi.org/10.2807/esm.01.01.00135-en.

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The Swedish Institute for Infectious Disease Control (Smittskyddsinstitutet - SMI) received no more than three reports of enterohaemorrhagic E. coli O157 infections (EHEC) each year from 1988 to 1994. About half of these were due to E. coli O157. In July

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Journal, Baghdad Science. "Effect of Citrus aurantifolia Seed Extracts In Some Bacteria Isolated From Burns Infections." Baghdad Science Journal 11, no. 2 (June 1, 2014): 773–80. http://dx.doi.org/10.21123/bsj.11.2.773-780.

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The present study was carried to evaluate antibacterial activity of Acetone, Alcholic (cold and hot) and Aqueaus(water) extracts of Citrus aurantifoliaseeds,against growth of some bacteria isolated from burns infections(Pseudomonas aeruginosa,Escherichia coli, Klebsiellapneumonia,Staphylococcusaureus)fromKindy HospitalIn Baghdad from March to June 2012.Antibiotic Sensitivity was done for all isolated bacteria used in this study.Results showed variation in antibacterial activity of different extracts against all tested bacteria by well diffusion technique in agar and measuring the diameter of inhibition zone, at concentration 250Mg-ml. Acetone extract had the greatest inhibitory effect followed by hot alcoholci extract, and then cold alcoholic extract,while the aqueous extract slightly inhibited bacteria. Minimum inhibitory concentration(MIC)were determined for all extracts against studying bacteria and found(12.5-50)mg-ml for acetone and alcoholic extracts, MIC for aqueous extract was 50mg-ml forPseudomonasaeruginosa and Escherichia coli,while was no effect onKlebsiellapneumonia and Staphylococcusaureus. Minimum Bacterial Concentration(MBC)were determined and was found25-50mg-ml for acetone extract,hot water was25mg-ml, cold alcoholic extract was 50mg-ml forPseudomonasaeruginosa,Escherichia coli andKlebsiella pneumonia but showed no effect on Staphylococcus aureus, aqueous extract showed negative effect on alltested bacteria. The antimicrobial activity of hot alcoholic extract of seeds was investigated practically (in vivo) by treating burns mices infected with tested bacteria(Pseudomonas aeruginosa,Escherichia coli and Klebsiellapneumonia),the results revealed good recovery at short time comparing with antibiotic(Flamazine) used at the same time.

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Fang, Guodong. "Intestinal Escherichia coli infections." Current Opinion in Infectious Diseases 6, no. 1 (February 1993): 48–53. http://dx.doi.org/10.1097/00001432-199302000-00011.

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Thielman, Nathan M. "Enteric Escherichia coli infections." Current Opinion in Infectious Diseases 7, no. 5 (October 1994): 582–91. http://dx.doi.org/10.1097/00001432-199410000-00012.

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Dharmik, Preeti G., Ashok V. Gomashe, and Bharat J. Wadher. "Citric acid: A potential permeabilizer against multiple drug resistance enteropathogenic Escherichia coli." Journal of Applied and Natural Science 4, no. 1 (June 1, 2012): 87–91. http://dx.doi.org/10.31018/jans.v4i1.229.

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Enteric diseases enter through the mouth and are usually spread by contaminated food, water or contact with contaminated vomit or feces. Enteric infection encompasses all the infections of the intestinal tract. These intestinal infections include organisms like Escherichia coli, Salmonella, Shigella, Klebsiella, Proteus etc. Out of these, E. coli are one of the common causes of enteric infection. In spite the introduction of a wide variety of antimicrobial agents against enteric diseases, life threatening infections caused by E. coli contributes to morbidity and mortality in patients. The present study was conducted to determine the antibiotic sensitivity pattern of E. coli obtained from stool samples and potentiation of antibiotic activity by citric acid against multiple drug resistant E. coli. Out of the 200 isolates of E. coli, 150 were found to be resistant to one or more antibiotics tested. 0.05% and 0.1% citric acid was found to be effective in increasing the potency of the all the antibiotics used in the study.

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Kundu, Rajib, Swapan Das, and Bani P. Chattopadhyay. "Microbiological profile of urinary tract infection in patients with burn injuries." International Surgery Journal 8, no. 9 (August 27, 2021): 2695. http://dx.doi.org/10.18203/2349-2902.isj20213598.

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Background: As per WHO around 1,95,000 people died every year due to burn injuries. After initial 72 hours, Infections are the most common cause of death in patients with burn injuries and urinary tract infection was second most commonly reported infectious complication. This study was tried to determine the pattern of microorganisms responsible for urinary tract infection.Methods: After matching inclusion and exclusion criteria, total 55 patients were taken for this institution based prospective observational study. Samples were collected on day 7 and cultured aerobically in MacConkey agar and 5% blood agar and antibiotic susceptibility testing was done on Muller Hinton agar using Kirby-Bauer disc diffusion method.Results: 29.1% samples were positive for microorganisms, of which Escherichia coli was most common isolated organism, it is found in 18.2 % of study population. nitrofurantoin was found to be most effective antibiotic against Escherichia coli.Conclusions: Gram-negative cocci were most prevalent organisms, causing urinary tract infection in patients with burn injuries. Escherichia coli was most common isolated organism and nitrofurantoin was most effective against it. Overall piperacillin/tazobactam has height sensitivity.

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Morton, V., JM Cheng, D. Sharma, and A. Kearney. "Éclosion d'infections à Escherichia coli O121 producteur de Shiga-toxine associée à de la farine au Canada - 2016-2017." Relevé des maladies transmissibles au Canada 43, no. 7/8 (July 6, 2017): 173–74. http://dx.doi.org/10.14745/ccdr.v43i78a03f.

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Anggraini, Agnina Listya, Ratih Dewi Dwiyanti, and Anny Thuraidah. "Garlic Extract (Allium sativum L.) Effectively Inhibits Staphylococcus aureus and Escherichia coli by Invitro Test." Tropical Health and Medical Research 2, no. 2 (August 26, 2020): 61–68. http://dx.doi.org/10.35916/thmr.v0i0.22.

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Infection is a disease caused by the presence of pathogenic microbes, including Staphylococcus aureus and Escherichia coli. Garlic (Allium sativum L.) has chemical contents such as allicin, alkaloids, flavonoids, saponins, tannins, and steroids, which can function as an antibacterial against Staphylococcus aureus and Escherichia coli. This study aims to determine the antibacterial properties of garlic extract powder against Staphylococcus aureus and Escherichia coli. This research is the initial stage of the development of herbal medicines to treat Staphylococcus aureus and Escherichia coli infections. The antibacterial activity test was carried out by the liquid dilution method. The concentrations used were 30 mg/mL, 40 mg/mL, 50 mg/mL, 60 mg/mL and 70 mg/mL. The results showed that the Minimum Inhibitory Concentration (MIC) against Staphylococcus aureus and Escherichia coli was 40 mg/mL and 50 mg / mL. Minimum Bactericidal Concentration (MBC) results for Staphylococcus aureus and Escherichia coli are 50 mg/mL and 70 mg/mL. Based on the Simple Linear Regression test, the R2 value of Staphylococcus aureus and Escherichia coli is 0.545 and 0.785, so it can be concluded that there is an effect of garlic extract powder on the growth of Staphylococcus aureus and Escherichia coli by 54.5% and 78.5%. Garlic (Allium sativum L.) extract powder has potential as herbal medicine against bacterial infections but requires further research to determine its effect in vivo.

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K. Prakash, J. Shravan Kumar, J. Rajamouli, and Sachin Gurnule. "A Study on Prevalence of Serum Resistant & Sensitive Escherichia Coli in Urinary Tract Infection." Asian Journal of Medical Research 9, no. 4 (December 30, 2020): 1–6. http://dx.doi.org/10.47009/ajmr.2020.9.4.mb1.

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Background: Escherichia coli is the commonest organism causing urinary tract infection in women and children especially in those with uncom- plicated infections. It has been traditionally described Serotypes of Escherichia coli were consistently associated with Uropathogenicity and designated as Uropathogenic Escherichia coli.It is now recognized that a subset of fecal Escherichia coli can be colonized in the peri-urethral area, enter the urinary tract and cause symptomatic disease. These are currently defined as Uropathogenic Escherichia coli. The aims & objectives are to the isolation of Escherichia coli in Urinary tract infection. 2. To determine the prevalence of Serum resistant Uropathogenic Escherichia coli. 3. To compare antimicrobial efficacy in Serum resistant and Serum sensitive Uropathogenic Escherichia coli. Subjects & Methods: An observational study was conducted on 100 patients and urine samples collected from suspected and suffering from urinary tract infection. Study period from August 2018 to July 20019 attending General medicine OP in Hospital. Escherichia coli were isolated and identified by conventional techniques Mackie & Mc Cartney. The strains were subjected to multiple drugs to study serum resistance and sensitivity. Results: From 100 urine samples 71 Uropathogenic, 18 males & 53 females. 40% Sero-resistant and 60% Sero-sensitive among them 2 to 18 years males and > 40 years females resistant, above 40 years males and 19 to 40 years females are sensitive to multiple antibiotics. Conclusion: it emphasizes Serum resistance is an important virulence factor, It may lead to pyelonephritis and septicemia. Serum resistant E. coli are multiple drug-resistant, so the present study formulating guidelines for planning effective treatment and Periodic surveillance to monitor resistance.

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Saade, Elie Antoun, Nuntra Suwantara, Trina F. Zabarsky, Brigid Wilson, and Curtis J. Donskey. "Fluoroquinolone-Resistant Escherichia coli Infections after Transrectal Biopsy of the Prostate in the Veterans Affairs Healthcare System." Pathogens and Immunity 1, no. 2 (September 20, 2016): 243. http://dx.doi.org/10.20411/pai.v1i1.123.

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Background: Recent reports suggest that infections due to fluoroquinolone-resistant Escherichia coli (E. coli) are an increasingly common complication of transrectal biopsy of the prostate (TBP) in the United States. A better understanding of the magnitude and scope of these infections is needed to guide prevention efforts. Our objective is to determine whether the incidence of infections due to fluoroquinolone-resistant E. coli after TBP has increased nationwide in the Veterans Affairs Health Care System and to identify risk factors for infection.Methods: We performed a retrospective, observational cohort study and a nested case-control study within the US Deparment of Veterans Affairs Healthcare System. The primary outcomes were the incidence of urinary tract infection (UTI) and bacteremia with E. coli and with fluoroquinolone-resistant E. coli strains within 30 days after TBP. Secondary endpoints focused on the correlation between fluoroquinolone-resistance in all urinary E. coli isolates and post-TBP infection and risk factors for infection due to fluoroquinolone-resistant E. coli infection.Results: 245 618 patients undergoing 302 168 TBP procedures from 2000 through 2013 were included in the cohort study, and 59 469 patients undergoing TBP from 2011 through 2013 were included in the nested case-control study. Between 2000 and 2013, there was a 5-fold increase in the incidence of E. coli UTI (0.18%–0.93%) and a 4-fold increase in the incidence of E. coli bacteremia (0.04%–0.18%) after TBP that was attributable to an increase in the incidence of fluoroquinolone-resistant E. coli UTI (0.03%–0.75%) and bacteremia (0.01%–0.14%). The increasing incidence of fluoroquinolone-resistant E. coli infections after TBP occurred in parallel with increasing rates of fluoroquinolone-resistance in all urinary E. coli isolates. By multivariable logistic regression analysis, independent risk factors for fluoroquinolone-resistant E. coli UTI after TBP included diabetes mellitus, fluoroquinolone exposure, prior hospitalization, and prior cultures with fluoroquinolone-resistant gram-negative bacilli.Conclusion: In the Veterans Affairs Healthcare System, the incidence of E. coli infection after TBP has increased significantly since 2000 due to a dramatic rise in infections with fluoroquinolone-resistant E. coli.Keywords: bacteremia; case-control studies; cohort studies; early detection of cancer; Escherichia coliinfections; microbial drug resistance; postoperative complications; prostate; retrospective studies; United States Department of Veterans Affairs; urinary tract infections.

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Saade, Elie Antoun, Nuntra Suwantara, Trina F. Zabarsky, Brigid Wilson, and Curtis J. Donskey. "Fluoroquinolone-Resistant Escherichia coli Infections after Transrectal Biopsy of the Prostate in the Veterans Affairs Healthcare System." Pathogens and Immunity 1, no. 2 (September 20, 2016): 243. http://dx.doi.org/10.20411/pai.v1i2.123.

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Background: Recent reports suggest that infections due to fluoroquinolone-resistant Escherichia coli (E. coli) are an increasingly common complication of transrectal biopsy of the prostate (TBP) in the United States. A better understanding of the magnitude and scope of these infections is needed to guide prevention efforts. Our objective is to determine whether the incidence of infections due to fluoroquinolone-resistant E. coli after TBP has increased nationwide in the Veterans Affairs Health Care System and to identify risk factors for infection.Methods: We performed a retrospective, observational cohort study and a nested case-control study within the US Deparment of Veterans Affairs Healthcare System. The primary outcomes were the incidence of urinary tract infection (UTI) and bacteremia with E. coli and with fluoroquinolone-resistant E. coli strains within 30 days after TBP. Secondary endpoints focused on the correlation between fluoroquinolone-resistance in all urinary E. coli isolates and post-TBP infection and risk factors for infection due to fluoroquinolone-resistant E. coli infection.Results: 245 618 patients undergoing 302 168 TBP procedures from 2000 through 2013 were included in the cohort study, and 59 469 patients undergoing TBP from 2011 through 2013 were included in the nested case-control study. Between 2000 and 2013, there was a 5-fold increase in the incidence of E. coli UTI (0.18%–0.93%) and a 4-fold increase in the incidence of E. coli bacteremia (0.04%–0.18%) after TBP that was attributable to an increase in the incidence of fluoroquinolone-resistant E. coli UTI (0.03%–0.75%) and bacteremia (0.01%–0.14%). The increasing incidence of fluoroquinolone-resistant E. coli infections after TBP occurred in parallel with increasing rates of fluoroquinolone-resistance in all urinary E. coli isolates. By multivariable logistic regression analysis, independent risk factors for fluoroquinolone-resistant E. coli UTI after TBP included diabetes mellitus, fluoroquinolone exposure, prior hospitalization, and prior cultures with fluoroquinolone-resistant gram-negative bacilli.Conclusion: In the Veterans Affairs Healthcare System, the incidence of E. coli infection after TBP has increased significantly since 2000 due to a dramatic rise in infections with fluoroquinolone-resistant E. coli.Keywords: bacteremia; case-control studies; cohort studies; early detection of cancer; Escherichia coliinfections; microbial drug resistance; postoperative complications; prostate; retrospective studies; United States Department of Veterans Affairs; urinary tract infections.

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Flores, Jose, and Pablo C. Okhuysen. "Enteroaggregative Escherichia coli infection." Current Opinion in Gastroenterology 25, no. 1 (January 2009): 8–11. http://dx.doi.org/10.1097/mog.0b013e32831dac5e.

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TARR, PHILLIP I., THOMAS E. BESSER, DALE D. HANCOCK, WILLIAM E. KEENE, and MARCIA GOLDOFT. "Verotoxigenic Escherichia coli Infection: U.S. Overview†." Journal of Food Protection 60, no. 11 (November 1, 1997): 1466–71. http://dx.doi.org/10.4315/0362-028x-60.11.1466.

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Escherichia coli O157:H7 remains a public health problem in the United States despite a dramatic increase in the awareness of, and concern about, foodborne infections since the 1993 multistate E. coli O157:H7 epidemic. Although surveillance data can be difficult to interpret, the incidence of endemic disease caused by this organism is probably not increasing, and might be decreasing, at least in selected populations. With increased recognition of E. coli O157:H7 infection has come the investigation of increasing number of outbreaks, leading to the recognition of many “new” vehicles, including some foods not traditionally associated with enteric infections, such as dry-cured salami and lettuce. Molecular fingerprinting techniques are being used to track the transmission of E. coli O157:H7 through human populations. Analysis of DNA encoding virulence factors and surface antigens suggests that diarrheagenic E. coli have evolved by acquiring large DNA fragments, with subsequent chromosomal recombination. Some Shiga toxin–producing E. coli other than E. coli O157:H7 are no doubt pathogens, but the majority of these toxigenic strains found in food are probably not virulent. More research is needed to define the characteristics that render selected Shiga toxin–producing organisms harmful to humans.

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CRUMP, JOHN A., CHRISTOPHER R. BRADEN, MEGHAN E. DEY, R. MICHAEL HOEKSTRA, JANET M. RICKELMAN-APISA, DAVID A. BALDWIN, SIETSKE J. DE FIJTER, et al. "Outbreaks of Escherichia coli O157 infections at multiple county agricultural fairs: a hazard of mixing cattle, concession stands and children." Epidemiology and Infection 131, no. 3 (December 2003): 1055–62. http://dx.doi.org/10.1017/s0950268803001237.

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Escherichia coli O157 infections cause an estimated 60 deaths and 73000 illnesses annually in the United States. A marked summer peak in incidence is largely unexplained. We investigated an outbreak of E. coli O157 infections at an agricultural fair in Ohio and implicated consumption of beverages made with fairground water and sold by a geographically localized group of vendors who were all on the same branch of the fairground water distribution system. To examine county fair attendance as a risk factor for infection, we conducted two further epidemiological studies. In the first, we enhanced surveillance for E. coli O157 infections in 15 Northeast Ohio counties during the 2000 agricultural fair season and showed increased risk of E. coli O157 infection among fair attendees. In the second study, we examined Ohio Public Health Laboratory Information Service (PHLIS) data for 1999 using a time-varying covariate proportional hazards model and demonstrated an association between agricultural fairs and E. coli O157 infections, by county. Agricultural fair attendance is a risk factor for E. coli O157 infection in the United States and may contribute to the summer peak in incidence. Measures are needed to reduce transmission of enteric pathogens at agricultural fairs.

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Das, Bitopan, Mrinmoy Sarma, Rohit Kumar, Palashi Borah, Sushama Sinha, Prasanna Gupta, and Pushpa Durlabhji. "Isolation, identification and antibiotic sensitivity pattern of Escherichia coli isolated from various clinical sample in a tertiary care hospital, Jaipur, Rajasthan, India." International Journal of Research in Medical Sciences 8, no. 5 (April 27, 2020): 1774. http://dx.doi.org/10.18203/2320-6012.ijrms20201925.

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Background: Escherichia coli is one of the most frequent causes of many bacterial infections, including Urinary Tract Infections (UTI), blood stream infections, otitis media, pneumonia, meningitis, traveler’s diarrhoea, enteric infections and systemic infections. This study was done with the aim to surveying antibiotic sensitivity pattern of isolated Escherichia coli in both sex attended in NIMS Hospital, Jaipur under the taken time period.Methods: In this cross-sectional study, 62 Escherichia coli were isolated from various clinical specimens of the patients attending both OPD and IPD. The strains were selected using the laboratory standard methods and culture-specific. The antibiotic susceptibility testing was performed using Kirby-Bauer disk diffusion method.Results: Out of total 62 isolates of Escherichia coli 26(41.93%) isolates were from male while 36(58.064%) from female patients. Maximum sensitivity were shown by Polymyxin B and Colistin i.c 100% followed by Nitrofuratonin 82.5% followed by Meropenem 79.03%, Aztreonam 72.58%, Piperacillin/ Tazobactam and Ciprofloxacin 61.30%, each Amikacin 56.45%, Imipenem 54.83%, Ofloxacin 45.16%, Cefepime 43.54%, Ceftazidime 38.71%, Gentamycin and Ceftriaxone 37.09% each, Cefotaxime 30.64%, Norfloxacin 27.5%. Maximum resistance shown against Norfloxacin 72.5%, followed by Gentamycin and Ceftriaxone 62.90%, Ceftazidime 61.30%.Conclusions: Escherichia coli infected more in urinary tract infection as compare to other sample in human, and it is common in female than male. Regular monitoring of antimicrobial susceptibility for E.coli is recommended to improve treatment. A changing trend in antibiotic sensitivity profile of the isolates need to be monitored as there is limited availability of newer drugs and the emergence of resistant bacteria far exceeds the rate of new drug development.

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Neto, Ulysses Fagundes, and Isabel C. Affonso Scaletsky. "Escherichia coli infections and malnutrition." Lancet 356 (December 2000): S27. http://dx.doi.org/10.1016/s0140-6736(00)92013-0.

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Sanz-García, Marta, Ana Fernández-Cruz, Marta Rodríguez-Créixems, Emilia Cercenado, Mercedes Marin, Patricia Muñoz, and Emilio Bouza. "Recurrent Escherichia coli Bloodstream Infections." Medicine 88, no. 2 (March 2009): 77–82. http://dx.doi.org/10.1097/md.0b013e31819dd0cf.

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Roberts, James R. "Escherichia coli 0157:H7 Infections." Emergency Medicine News 26, no. 13 (January 2004): 20–22. http://dx.doi.org/10.1097/00132981-200401000-00020.

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Bergin, Stephen P., Joshua T. Thaden, Jessica E. Ericson, Heather Cross, Julia Messina, Reese H. Clark, Vance G. Fowler, Daniel K. Benjamin, Christoph P. Hornik, and P. Brian Smith. "Neonatal Escherichia coli Bloodstream Infections." Pediatric Infectious Disease Journal 34, no. 9 (September 2015): 933–36. http://dx.doi.org/10.1097/inf.0000000000000769.

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Burke, D. "Escherichia coli in intestinal infections." Biomedicine & Pharmacotherapy 43, no. 7 (January 1989): 534. http://dx.doi.org/10.1016/0753-3322(89)90120-0.

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ZHANG, D. Y., J. Y. ZHOU, J. FANG, J. X. HU JQ WU, and A. X. MU. "An ELISA for antibodies to infectious bronchitis virus based on nucleocapsid protein produced in Escherichia coli." Veterinární Medicína 50, No. 8 (March 28, 2012): 336–44. http://dx.doi.org/10.17221/5632-vetmed.

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The nucleocapsid (N) gene of infectious bronchitis virus (IBV) strain X isolated in Chinawas expressed in E. coli and was purified as a recombinant protein. An indirect ELISA assay (N-ELISA) for antibody detection was established using the purified recombinant nucleocapsid protein. Antigen coating conditions and serum dilution for the N-ELISA were optimized. The S/P ratio of the absorbency value was calculated in the N-ELISA to evaluate the antibody level of chicken serum. In an experiment to test field samples for antibody detection, the N-ELISA assay shared 95.7% identity of total positive ratio with the commercial ELISA kit. It indicated that the N-ELISA assay, which was safer and easier to prepare than traditional methods, was a good candidate for evaluation of IB vaccine efficiency and virus exposure.

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Sacerdoti, Flavia, María Scalise, Juliana Burdet, María Amaral, Ana Franchi, and Cristina Ibarra. "Shiga Toxin-Producing Escherichia coli Infections during Pregnancy." Microorganisms 6, no. 4 (October 23, 2018): 111. http://dx.doi.org/10.3390/microorganisms6040111.

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Gastrointestinal infection with Shiga toxin-producing Escherichia coli (STEC) causes diarrhea, hemorrhagic colitis, and hemolytic uremic syndrome (HUS), characterized by hemolytic anemia, thrombocytopenia and acute renal failure. The main virulence factor of STEC is Shiga toxin (Stx), which is responsible for HUS development. STEC can produce Stx type 1 and/or 2 (Stx1, Stx2) and their variants, Stx2 being more frequently associated with severe cases of HUS. This pathology occurs in 5–15% of cases with STEC infection when Stx gain access to the bloodstream and causes damage in the target organs such as the kidney and brain. STEC infections affect mainly young children, although the large HUS outbreak with a new Stx2-producing STEC O104:H4 in Europe in 2011 involved more adults than children, and women were over-represented. Maternal infections during pregnancy are associated with adverse pregnancy outcomes. Studies in rats showed that Stx2 binds to the utero-placental unit and causes adverse pregnancy outcomes. In this article, we provide a brief overview of Stx2 action on placental tissues and discuss whether they might cause pregnancy loss or preterm birth.

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Manning, Sara, Ebbing Lautenbach, Pam Tolomeo, and Jennifer H. Han. "Risk Factors for Infection with Escherichia coli in Nursing Home Residents Colonized with Fluoroquinolone-Resistant E. coli." Infection Control & Hospital Epidemiology 36, no. 5 (January 23, 2015): 575–77. http://dx.doi.org/10.1017/ice.2015.3.

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A case-control study to determine risk factors for clinical infection with Escherichia coli was conducted among nursing home residents colonized with fluoroquinolone-resistant E. coli. Among 94 subjects, 11 (12%) developed infections with E. coli. Risk factors included the presence of a urinary catheter or tracheostomy, diabetes mellitus, and trimethoprim-sulfamethoxazole exposure.Infect Control Hosp Epidemiol 2015;00(0): 1–3

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WILSON, JEFFREY B., ROGER P. JOHNSON, ROBERT C. CLARKE, KRIS RAHN, SHANE A. RENWICK, DAVID ALVES, MOHAMED A. KARMALI, PASCAL MICHEL, ELAINE ORRBINE, and JOHN S. SPIKA. "Canadian Perspectives on Verocytotoxin-Producing Escherichia coli Infection†." Journal of Food Protection 60, no. 11 (November 1, 1997): 1451–53. http://dx.doi.org/10.4315/0362-028x-60.11.1451.

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Infection with verocytotoxin-producing Escherichia coli (VTEC) became nationally reportable in 1990. Between 1990 and 1994, the national incidence of reported infections ranged from 3 to 5.3 per 100,000 inhabitants. Most cases are sporadic and are caused by E. coli O157:H7. Recent investigations have identified that, in addition to exposure to undercooked ground beef, contact with cattle, consumption of well water, and exposure to rural environments are important risk factors for VTEC infection. Also, results of case control studies and detection of asymptomatic fecal carriage of E. coli O157:H7 and other VTEC in farm family members and abattoir workers have led to an increasing emphasis on person-to-person spread in the epidemiology of VTEC infection. Controlling E. coli O157:H7 and other VTEC at the farm level may therefore have a broader impact than simply reducing the risk of foodborne VTEC infection. Longitudinal studies on dairy farms have demonstrated that E. coli O157:H7 carriage by cattle at the farm and animal level is often transient, and that cattle, rather than the farm environment, are the major reservoir for this organism on dairy farms. Small herds that are controlled by traditional management practices have the highest risk for VTEC infection. Further studies are likely to result in development of effective strategies to control VTEC at the farm level.

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Dumford, Donald, Nuntra Suwantarat, Vineet Bhasker, Sirisha Kundrapu, Trina F. Zabarsky, Paul Drawz, Hui Zhu, and Curtis J. Donskey. "Outbreak of Fluoroquinolone-Resistant Escherichia coli Infections after Transrectal Ultrasound—Guided Biopsy of the Prostate." Infection Control & Hospital Epidemiology 34, no. 3 (March 2013): 269–73. http://dx.doi.org/10.1086/669512.

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Design.We conducted an investigation after identifying a cluster of 4 serious infections following transrectal ultrasound–guided biopsy of the prostate (TRUBP) during a 2-month period.Setting.veterans Affairs medical center.Patients.Patients with urinary tract infection (UTI) after TRUBP and time-matched controls with no evidence of infection.Methods.The incidence of UTI within 30 days after TRUBP was calculated from 2002 through 2010. We evaluated the correlation between infection with fluoroquinolone-resistant gram-negative bacilli (GNB) and fluoroquinolone resistance in outpatient Escherichia coli urinary isolates and performed a case-control study to determine risk factors for infection with fluoroquinolone-resistant GNB. Processes for TRUBP prophylaxis, procedures, and equipment sterilization were reviewed.Results.An outbreak of UTI due to fluoroquinolone-resistant E. coli after TRUBP began 2 years before the cluster was identified and was correlated with increasing fluoroquinolone resistance in outpatient E. coli. No deficiencies were identified in equipment processing or biopsy procedures. Fluoroquinolone-resistant E. coli UTI after TRUBP was independently associated with prior infection with fluoroquinolone-resistant GNB (adjusted odds ratio, 20.8; P = .005). A prediction rule including prior UTI, hospitalization in the past year, and previous infection with fluoroquinolone-resistant GNB identified only 17 (49%) of 35 cases.Conclusions.The outbreak of fluoroquinolone-resistant E. coli infections after TRUBP closely paralleled rising rates of fluoroquinolone resistance among outpatient E. coli isolates. The delayed detection of the outbreak and the absence of sensitive predictors of infection suggest that active surveillance for infection after TRUBP is necessary in the context of increasing fluoroquinolone resistance in the United States.

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Regasa Dadi, Belayneh, Tamrat Abebe, Lixin Zhang, Adane Mihret, Workeabeba Abebe, and Wondwossen Amogne. "Drug resistance and plasmid profile of uropathogenic Escherichia coli among urinary tract infection patients in Addis Abeba." Journal of Infection in Developing Countries 12, no. 08 (August 31, 2018): 608–15. http://dx.doi.org/10.3855/jidc.9916.

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Introduction: Urinary tract infection is a major cause of morbidity and mortality worldwide. Uropathogenic Escherichia coli bacteria are the most common cause of urinary tract infections. Drug resistant Escherichia coli is results in high levels of treatment failure and can be a significant threat to survival of patients. Methodology: Escherichia coli bacteria were isolated using culture and conventional biochemical tests. Antimicrobial susceptibility testing and plasmid profile were performed using the Kirby Bauer disc diffusion method and plasmid analysis. Data was processed with SPSS version 16.0 and Epi-info version 3.4.1 software. Results: The highest proportion of Escherichia coli isolates was resistant to (86.5%) to ampicillin, followed by ceftazidime (84%), ceftriaxone (80.5%), tetracycline (80%), trimethoprim-sulfamethoxazole (68.5%) and cefotaxime (66%). Escherichia coli isolates were most susceptible to meropenem (100%), imipenem (100%), amikacin (97.5%), nitrofurantoin (95%), ciprofloxacin (85.5%), norfloxacin (85%), chloramphenicol (83.5%), gentamycin (80%) and nalidixic acid (79%). Multidrug resistance (MDR) was observed in most (96.5%) E. coli isolates. Plasmid analysis revealed the presence of plasmid(s) in 165 (82.5%) of the E. coli isolates many of which had a plasmid size of 23 kb. Conclusions: The overall incidence of antibiotic resistance (including MDR) among E. coli in this study was high to commonly used antibiotics, but no drug resistance to meropenem and imipenem was observed. Periodic monitoring of the drug resistance pattern is essential for better management of urinary tract infections, which has direct impact on the outcome of the patient.

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Puvabanditsin, Surasak, Marianne Jacob, Maaz Jalil, Samhita Bhattarai, Qaiser Patel, Mehrin Sadiq, and Rajeev Mehta. "Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Meningitis and Cerebral Abscess in a Neonate: Therapeutic Challenge." Case Reports in Infectious Diseases 2019 (March 28, 2019): 1–5. http://dx.doi.org/10.1155/2019/6874192.

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We report a case of a 12-day-old term neonate with extended-spectrum beta-lactamase (ESBL) producing Escherichia coli (E. coli) meningitis and cerebral abscess. The patient received a 7-day course of antibiotics just few days prior to the infection. The incidence of infections from ESBL-producing E. coli is increasingly emerging. Antimicrobial agents must be vigilantly utilized to prevent the new highly resistant bacteria.

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Bispo, Ana, Milene Fernandes, Cristina Toscano, Teresa Marques, Domingos Machado, and André Weigert. "Infeções do Trato Urinário numa Coorte de Transplantados Renais." Acta Médica Portuguesa 27, no. 3 (June 30, 2014): 364. http://dx.doi.org/10.20344/amp.4959.

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Introduction: Urinary tract infection is the most common infectious complication following renal transplantation and its frequency is insufficiently studied in Portugal. The aim of this study was to characterize the incidence of urinary tract infections and recurrent urinary tract infections in renal transplant recipients. Material and Methods: This was a retrospective cohort observational study, obtained from clinical files of all patients who received a renal transplant at the Hospital of Santa Cruz, from January 2004 to December 2005, with a mean follow-up period of five years or until date of graft loss, death or loss of follow-up. After a descriptive analysis of the population, we used bivariate tests to identify risk factors for urinary tract infections. Results: A total of 127 patients were included, with a 593 patients.year follow-up. We detected 53 patients (41.7%) presenting with at least one episode of urinary tract infection; 21 patients (16.5%) had recurrent urinary tract infection. Female gender was the only risk factor associated with the occurrence of urinary tract infections (p < 0.001, OR = 7.08, RR = 2.95) and recurrent urinary tract infections (p < 0.001, OR = 4.66, RR = 2.83). Escherichia coli (51.6%), Klebsiella pneumoniae (15.5%) and Enterobacter spp (9.9%) were the most frequently identified pathogens. Patients did not reveal an increased mortality or allograft loss. However, urinary tract infections were the most important cause of hospital admissions. Discussion: Female gender was the only risk factor for urinary tract infections in this population. Escherichia coli was the most frequent agent isolated. Conclusion: Despite preventive measures, urinary tract infections remain an important cause of morbidity and hospital admissions. Keywords: Urinary Tract Infections; Postoperative Complications; Risk Factors; Kidney Transplantation; Portugal.

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You, Xue-Fu, Cong-Ran Li, Xin-Yi Yang, Min Yuan, Wei-Xin Zhang, Ren-Hui Lou, Yue-Ming Wang, et al. "In Vivo Antibacterial Activity of Vertilmicin, a New Aminoglycoside Antibiotic." Antimicrobial Agents and Chemotherapy 53, no. 10 (July 27, 2009): 4525–28. http://dx.doi.org/10.1128/aac.00223-09.

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ABSTRACT Vertilmicin is a novel aminoglycoside antibiotic with potent activity against gram-negative and -positive bacteria in vitro. In this study, we further evaluated the efficacy of vertilmicin in vivo in systemic and local infection animal models. We demonstrated that vertilmicin had relatively high and broad-spectrum activities against mouse systemic infections caused by Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, and Enterococcus faecalis. The 50% effective doses of subcutaneously administered vertilmicin were 0.63 to 0.82 mg/kg, 0.18 to 0.29 mg/kg, 0.25 to 0.99 mg/kg, and 4.35 to 7.11 mg/kg against E. coli, K. pneumoniae, S. aureus, and E. faecalis infections, respectively. The therapeutic efficacy of vertilmicin was generally similar to that of netimicin, better than that of gentamicin in all the isolates tested, and better than that of verdamicin against E. coli 9612 and E. faecalis HH22 infections. The therapeutic efficacy of vertilmicin was further confirmed in local infection models of rabbit skin burn infection and mouse ascending urinary tract infection.

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Jakobsen, Lotte, Anette M. Hammerum, and Niels Frimodt-Møller. "Detection of Clonal Group A Escherichia coli Isolates from Broiler Chickens, Broiler Chicken Meat, Community-Dwelling Humans, and Urinary Tract Infection (UTI) Patients and Their Virulence in a Mouse UTI Model." Applied and Environmental Microbiology 76, no. 24 (October 29, 2010): 8281–84. http://dx.doi.org/10.1128/aem.01874-10.

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ABSTRACT Escherichia coli clonal group A isolates cause infections in people. We investigated 158 phylogroup D E. coli isolates from animals, meat, and humans. Twenty-five of these isolates were of clonal group A, and 15 isolates were shown to cause infection in a mouse urinary tract infection (UTI) model. We conclude that clonal group A isolates are found in both broiler chickens and broiler chicken meat and may cause UTI in humans.

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Cooke, E. Mary. "Escherichia coli – an overview." Journal of Hygiene 95, no. 3 (December 1985): 523–30. http://dx.doi.org/10.1017/s022217240006065x.

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The isolation and description of Bacillus coli commune by Escherich a hundred years ago marked the start of a series of scientific investigations which have led to some of the most important discoveries in microbial pathogenicity and genetics that have been made since that time. It is not difficult to find the reasons why so much effort has been concentrated on this organism. Escherichia coli is present in the gut of all warm-blooded animals generally forming the predominant aerobic flora; it is of medical and veterinary importance being responsible for a variety of infections in the human and animal populations and it has provided a useful tool for geneticists.

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BRZOZOWSKI, D., and D. C. ROSS. "Upper Limb Escherichia Coli Cellulitis in the Immunocompromised." Journal of Hand Surgery 22, no. 5 (October 1997): 679–80. http://dx.doi.org/10.1016/s0266-7681(97)80376-2.

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The neutropenic state characteristic of acute lymphoblastic leukaemia (ALL) predisposes to infections involving Gram-negative bacilli. An Escherichia coli cellulitis originating in the first web space of the hand is described in a patient undergoing reinductiori chemotherapy for ALL. Proximal extension of the infection progressed at a very rapid rate and required a forequarter amputation as a life saving measure. Due to the blunted inflammatory response in neutropenic patients, the need for close monitoring and quick intervention is stressed.

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Stetsko, T. I., Ya M. Liubenko, V. N. Padovskyi, L. L. Ostrovska, O. Yo Kalinina, and O. Z. Balyan. "Investigation of the antimicrobial activity of danofoloxacin against bacteria pathogens in goats." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 22, no. 97 (May 7, 2020): 74–78. http://dx.doi.org/10.32718/nvlvet9713.

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Fluoroquinolones are critical antimicrobials for both human and veterinary medicine. Due to their unique mechanism of antimicrobial action and good pharmacokinetic properties, they are often the first choice drugs in the treatment of bacterial infections in animals. The purpose of the investigation was to study the antimicrobial activity of a third-generation fluoroquinolone antibiotic of danofloxacin against bacteria, pathogens of respiratory and intestinal infection in goats. The samples of the nasal outflows (respiratory infection) and fecal masses (intestinal infection) were collected from clinically ill goats for microbiological studies. The sensitivity test of the microflora of the biomaterial, carried out by the disco-diffusion method, showed that the microorganisms of all the samples were sensitive to danofloxacin. Bacteria Streptococcus pneumonia (n = 10), Staphylococcus aureus (n = 4) and Escherichia coli (n = 2) were isolated and identified from nasal exudate samples (n = 10). Pathogenic strains of Escherichia coli were isolated from all faecal samples (n = 12). The degree of bacteriostatic activity of danofloxacin was determined by establishing its minimum inhibitory concentration (MIC) for bacterial isolates by sequential dilutions in a liquid nutrient medium. The average MIC of danofloxacin for Streptococcus pneumoniae isolates was 0.26 ± 0.13 μg/ml and for Staphylococcus aureus isolates – 0.25 ± 0.075 μg/ml. For Escherichia coli strains isolated from faeces of goats suffering from coli infection, the average MIC of danofloxacin was 0.38 ± 0.12 μg/ml (range 0.2 to 0.8 μg/ml). Antimicrobial sensitivity testing have shown a high level of bacteriostatic activity of danofloxacin against bacteria, pathogens of respiratory and intestinal infections in goats. This may be the argument for the use of danofloxacin-based chemotherapeutic agents in the treatment of bacterial infections in goats, especially for the empirical approach to therapy.

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Jhora, Sanya Tahmina, Shikha Paul, Bilkis Ara Begum, and Abul Quashem Chowdhury. "Antibiogram of Urinary Escherichia coli isolated in Sir Salimullah Medical College Mitford Hospital, Dhaka." Bangladesh Journal of Medical Microbiology 5, no. 2 (November 10, 2013): 23–26. http://dx.doi.org/10.3329/bjmm.v5i2.16934.

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Urinary tract infections (UTIs) are one of the most common infectious diseases & an important cause of morbidity in general population. More than 90% of all uncomplicated UTI s are caused by Esch. coli infection. The study was carried out in Department of Microbiology of Sir Salimullah Medical College & Mitford Hospital (SSMC& MH) Dhaka from October 2002 to September 2003. A total of 749 urine samples were studied of which 414 (55.27) showed significant growth. Among the 414 isolates, E sch. coli was the most predominant (82.61%) organism. Esch. coli was highly sensitive to Imipenem (95.02%) followed by Ceftriaxone (86.84%), Cefuroxime (67.54%), Gentamicin (66.08%), and Ceftazidime (55.84%) respectively. Low sensitivity patterns were shown against Nitrofurantoin (44.73%) & Ciprofloxacin (40.64%). The sensitivity to other antibiotics varied from 23.39% to as low as 2.63%. The aim of the present study was to observe the antibiotic sensitivity pattern of isolated Esch. coli from urine samples of patients admitted in inpatient department or visited the out patient department of Sir Salimullah Medical College & Mitford Hospital (SSMC& MH) Dhaka.DOI: http://dx.doi.org/10.3329/bjmm.v5i2.16934 Bangladesh J Med Microbiol 2011; 05 (02): 23-26

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Oishi, Kazunori, Yuichiro Yahata, and Yukihiro Akeda. "8. Enterohemorrhagic Escherichia Coli Infection." Nihon Naika Gakkai Zasshi 102, no. 11 (2013): 2854–59. http://dx.doi.org/10.2169/naika.102.2854.

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Kang, Jin-han. "Escherichia coli O157: H7 Infection." Korean Journal of Pediatric Infectious Diseases 1, no. 1 (1994): 6. http://dx.doi.org/10.14776/kjpid.1994.1.1.6.

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Kang, Jin-han. "Escherichia coli O157:H7 Infection." Korean Journal of Pediatric Infectious Diseases 4, no. 2 (1997): 335. http://dx.doi.org/10.14776/kjpid.1997.4.2.335.

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Weightman, N. C., and P. J. G. Kirby. "Nosocomial Escherichia coli O157 infection." Journal of Hospital Infection 44, no. 2 (February 2000): 107–11. http://dx.doi.org/10.1053/jhin.1999.0679.

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Bogdanos, Dimitrios P., Harold Baum, Diego Vergani, and Andrew K. Burroughs. "The Role ofE. coliInfection in the Pathogenesis of Primary Biliary Cirrhosis." Disease Markers 29, no. 6 (2010): 301–11. http://dx.doi.org/10.1155/2010/595078.

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Among various infectious agents possibly involved in the pathogenesis of primary biliary cirrhosis (PBC),Escherichia Coli (E. coli)has received special attention because of epidemiological and experimental evidence linking this bacterium with the disease's development. This review discusses early and more recent epidemiological studies associating recurrent urinary tract infections withE. coliand the development of PBC. We also critically review data provided over the years demonstrating disease-specific humoral and cellular immune responses againstE. coliantigens in patients with PBC. Finally, we assess the relevance of experimental findings reporting cross-reactive immunity between mimicking sequences ofE. coliand the major PBC mitochondrial antigens in the pathogenesis of the PBC. We also address the extent to which molecular mimicry and immunological cross-reactivity can be considered as a critical pathogenic process linking infection with self destruction.

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Journal articles on the topic 'Escherichai coli infections'

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