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Dissertations / Theses on the topic 'Escherichia coli infections Pathogenesis'

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1

Paton, Adrienne Webster. "Molecular characterization of variant shiga-like toxin genes of Escherichia coli /." Title page, contents and abstract only, 1993. http://web4.library.adelaide.edu.au/theses/09PH/09php3118.pdf.

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2

Srimanote, Potjanee. "Analysis of putative virulence factors of a locus of enterocyte effacement-negative shiga-toxigenic Escherichia coli O113:H21 strain." Title page, contents and abstract only, 2003. http://web4.library.adelaide.edu.au/theses/09PH/09php863.pdf.

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"February 2003." Addendum and corrigenda inserted at back Includes bibliographical references (leaves 249-272) Aims to identify and characterise potential virulence-associated factors from the locus of enterocyte effacement-negative shiga-toxigenic Escherichia coli O113:H21 strain 98NK2 which was responsible for an outbreak of haemolytic uremic syndrome. Particular attention was focused on putative virulence genes encoded on the megaplasmid of this strain.
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3

Rodrigues, Ângela Maria Gonçalves. "Patogénese das infeções entéricas por escherichia coli." Master's thesis, [s.n.], 2014. http://hdl.handle.net/10284/4840.

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Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências Farmacêuticas<br>As estirpes de E. coli podem ser agrupadas em estirpes comensais, patogénios extraintestinais e patogénios intestinais. É um relevante patogénio intestinal que causa infeções entéricas com grandes taxas de morbilidade e mortalidade em todo o mundo. O desenvolvimento da infeção depende da dose infeciosa ingerida pelo indivíduo, da sua susceptibilidade à doença, da interação entre o patogénio e os enterócitos e virulência do patogé
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4

Hostetter, Shannon Jones. "Role of Shiga toxin dissemination and inflammation in the pathogenesis of Shiga toxin-producing Escherichia coli infection." [Ames, Iowa : Iowa State University], 2009.

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5

Walz, Paul S. "Influence of pathogenic bacterial determinants on genome stability of exposed intestinal cells and of distal liver and spleen cells." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Biology, c2011, 2011. http://hdl.handle.net/10133/3405.

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Most bacterial infections can be correlated to contamination of consumables such as food and water. Upon contamination, boil water advisories have been ordered to ensure water is safe to consume, despite the evidence that heat-killed bacteria can induce genomic instability of exposed (intestine) and distal cells (liver and spleen). We hypothesize that exposure to components of heat-killed Escherichia coli O157:H7 will induce genomic instability within animal cells directly and indirectly exposed to these determinants. Mice were exposed to various components of dead bacteria such as DNA, RNA, p
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6

Lekmeechai, Sujinna. "The role of EspO1 in Escherichia coli pathogenesis." Thesis, Imperial College London, 2016. http://hdl.handle.net/10044/1/58146.

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Enterohaemorrhagic E. coli (EHEC) has been the causative agent of diarrhoeal outbreaks for decades. EHEC virulence relies on a type 3 secretion system (T3SS), which directly translocates T3SS effectors into the host cell cytoplasm. Once translocated, T3SS effectors alter various host cell functions, including manipulating the cell death response, in order to facilitate bacterial colonisation. EHEC is equipped with at least 40 effector proteins; however, not all identified effectors are fully characterised. This study set out to investigate the role of EspO during EHEC infection. EHEC O157:H7 s
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7

Burke, Denis Anthony. "Ulcerative colitis and Escherichia coli." Thesis, University of Newcastle Upon Tyne, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309075.

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8

Wu, Gilbert Kar Po. "Signal transduction responses to enteropathogenic Escherichia coli and Shiga toxin-producing Escherichia coli infections." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0007/MQ46054.pdf.

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9

Solecki, Olivia. "Explaining the urban and rural differences of Escherichia coli 0157 human infection in Grampian." Thesis, Available from the University of Aberdeen Library and Historic Collections Digital Resources, 2008. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=25203.

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10

Kimmitt, Patrick Thomas. "Expression of Shiga toxin genes in Escherichia coli." Thesis, University of Newcastle Upon Tyne, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299614.

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11

Henriques, Sofia Correia Rosa de Barros. "Escherichia coli : host interactions in the pathogenesis of canine pyometra." Doctoral thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2016. http://hdl.handle.net/10400.5/12273.

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Tese de Doutoramento em Ciências Veterinárias na Especialidade de Ciências Biológicas e Biomédicas<br>Canine pyometra develops as a result of a complex interaction of etiological and physiopathological factors, such as the virulence and type of the bacteria and the individual host defence mechanisms. Since Escherichia coli is the most common bacterium isolated from uterus of bitches with pyometra, one main objective of this work was to characterize E. coli virulence potential, and to evaluate the role of its virulence factors (VF) and traits in the pathogenesis of canine pyometra (Chapter
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12

Stevenson, Sam M. L., and University of Lethbridge Faculty of Arts and Science. "Transfer of rifampicin-resistant Escherichia coli among feedlot cattle." Thesis, Lethbridge : University of Lethbridge, Facutly of Arts and Science, 2002, 2002. http://hdl.handle.net/10133/237.

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Transfer and shedding of a rifampicin-resistant strain of Escherichia coli (RREC) among cattle was studied in a research feedlot comprised of 30 pens of 11 or 12 yearling steers. On 3 separate occasions, 9,6 and 6 of the 12 steers in 3 different peripheral pens in the lot were orally inoculated with 1011 cells of an unmodified RREC isolate from bovine feces. Fecal swabs were preformed on all 360 steers in the feedlot immediately prior to and at approximately 5-week intervals thereafter. Following inoculation, fecal grab samples were collected daily from all 12 pen mates for up to 4 months. In
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13

Fasugba, Oyebola. "Antimicrobial resistance in urinary tract infections caused by Escherichia coli." Thesis, Australian Catholic University, 2017. https://acuresearchbank.acu.edu.au/download/67ce6b272ae23ebc1ea1e8727d748f9cc7a61a59c3d5c0c98d2d1d0350c55a51/5885672/Fasugba_2017_Antimicrobial_resistance_in_urinary_tract_infections.pdf.

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Urinary tract infections (UTI) are one of the most common bacterial infections in hospital and community settings requiring antimicrobial treatment. Escherichia coli (E. coli), a bacterium frequently implicated in UTI, is becoming increasingly resistant to antimicrobials. Antimicrobial resistance (AMR) reduces the effectiveness of antimicrobial agents, leading to difficulty in treatment of patients, with the potential to prolong the duration of illness and increase mortality in patients. To date in Australia, there is a paucity of data comparing resistance patterns over time for hospital- and
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14

Cremet, Lise. "Physiopathologie des infections ostéo-articulaires sur matériel à Escherichia coli." Nantes, 2015. http://archive.bu.univ-nantes.fr/pollux/show.action?id=476e2187-f5ed-4fe6-a97b-2280632ebd5f.

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Les bacilles à Gram négatif sont impliqués dans 6 à 23% des infections ostéo-articulaires sur matériel (IOAM), et Escherichia coli est la première cause de ces infections. La pathogénèse des IOAMs à E. Coli reste encore mal connue. Dans le but de déterminer si les souches de E. Coli responsables d'IOAMs présentent une virulence spécifique et/ou une capacité particulière à échapper au système immunitaire, 30 souches cliniques de E. Coli isolées dans ce contexte ont été étudiées. Nos travaux soulignent le fort potentiel pathogène de la majorité des E. Coli isolés d'IOAMs, et indiquent que des so
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15

Racicot, Bergeron Catherine. "Food animal reservoir for extraintestinal pathogenic «Escherichia coli» causing human infections." Thesis, McGill University, 2011. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=104886.

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Studies of extraintestinal infections caused by genetically related strains of Escherichia coli among unrelated people have demonstrated the epidemic potential of this group of bacteria. These related extraintestinal pathogenic E. coli (ExPEC) may have a common source. Our group recently described how retail meat, particularly chicken, may be a reservoir for ExPEC causing human urinary tract infections (UTIs). By moving upstream on the farm to fork continuum, this study tests whether the reservoir for ExPEC is in food animals themselves. A total of 824 geographically and temporally matched E.
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Vincent, Caroline. "Food reservoir for «Escherichia coli» causing community- acquired urinary tract infections." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=95200.

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Closely related strains of Escherichia coli have been shown to cause extraintestinal infections in unrelated persons. This study tests whether a food reservoir may exist for these E. coli. Isolates from three sources collected over the same time period and geographic area were compared. The sources comprised E. coli isolates from women with urinary tract infection (UTI) (n = 353); retail meat (n = 417); and restaurant/ready-to-eat foods (n = 74). E. coli were evaluated for antimicrobial susceptibility and O:H serotype and compared by using six different genotyping methods. We identified 17 clo
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17

Bin, Thani Ali Salman. "Genomic diversity of ten Escherichia coli strains associated with bloodstream infections." Thesis, University of Leicester, 2009. http://hdl.handle.net/2381/4246.

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Escherichia coli are usually regarded as a harmless human colonic flora. However, pathogenic strains of E. coli have been associated with infections that could range from infected mucosal surfaces by intestinal pathogenic E. coli to the more severe cases of disseminated infections throughout the body by the extraintestinal pathogroups. The main focus of this project was to investigate the genomic contents of pathogenic bloodstream infection (BSI)-associated E. coli strains. This is because the genome contents of the E. coli BSI-associated isolates have not been well studied, with only few repo
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18

Houdouin, Véronique. "Caractérisation des souches de Escherichia coli responsables de pathologies extra-intestinales chez l'enfant : approche moléculaire et approche clinique." Paris 5, 2007. http://www.theses.fr/2007PA05D039.

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Pour mieux appréhender les mécanismes physiopathologiques impliqués dans les infections extra-intestinales à E. Coli chez l'enfant, nous avons recherché une relation entre les caractéristiques génétiques bactériennes et les facteurs pronostiques cliniques des méningites néonatales et des infections urinaires. Notre stratégie repose sur trois approches : une approche moléculaire globale et ciblée, une approche fonctionnelle associant mutagénèse et modèle de méningite expérimentale et une approche clinique. Nous avons retrouvé une relation négative entre la virulence bactérienne et la mortalité
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19

Edwards, Kelly Katherine. "Bacterial factors contributing to the pathogenesis of the hemolytic uremic syndrome." MU has:, 2002. http://wwwlib.umi.com/cr/mo/fullcit?p3060096.

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20

Karami, Nahid. "Antibiotic resistance and fitness of Escherichia coli in the infantile commensal microbiota /." Göteborg : Department of Clinical Bacteriology, Göteborg University, 2007. http://hdl.handle.net/2077/4418.

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21

MacRitchie, Laura. "Human campylobacteriosis : elucidating the exposure, disease burden, health cost and acceptability of interventions." Thesis, University of Aberdeen, 2012. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=195982.

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Campylobacter is the most commonly reported bacterial cause of gastrointestinal disease in developed countries. Campylobacteriosis is an infectious disease that causes severe diarrhoea, abdominal cramps, vomiting, blood in stools and fever, along with the inability to carry out normal activities for an estimated 3-5 days. Long term sequelae associated with Campylobacter infection includes Guillain Barré syndrome, irritable bowel syndrome and reactive arthritis. The incidence of human campylobacteriosis in the Grampian region was 138.8 per 100,000 people in 2011 which was one of the highest inc
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22

Omolajaiye, Sunday Abraham. "Isolation and characterization of E. coli and Campylobacter spp. from diarrhoeal samples collected from selected hospitals in Amathole District Municipality, Eastern Cape, South Africa." Thesis, University of Fort Hare, 2018. http://hdl.handle.net/10353/6213.

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Approximately 2-4 billion cases of infectious diarrhoea occur every year, with the highest numbers recorded in sub-Saharan Africa. It remains the most common public health issue among children in developing nations. The purpose of this research was to unfold the prevalence of diarrhoeagenic E. coli and Campylobacter pathotypes as well as elucidate their antibiogram characteristics in diarrhoeal stool samples collected in some medical facilities in Eastern Cape Province, South Africa. Two hundred stool samples were collected from both inpatients and outpatients from male and females of all age
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23

Chu, Pui-shan, and 朱佩珊. "Antimicrobial resistant escherichia coli and sequence type 131 in urinary tract infections." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206499.

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Background A pandemic clone, Escherichia coli sequence type 131 (ST131), has been disseminated worldwide and represents an important cause of antimicrobial resistant infections. The spread of this resistant clone has become a great public health concern. Objectives The aims of this study were to investigate the prevalence of ST131 in Escherichia coli isolates from human urinary cultures in Hong Kong and study the antimicrobial phenotypes of ST131. Methodology This study included 340 E. coli clinical urinary isolates obtained from patients in four district hospitals between May 2013
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24

McPeake, Stuart John William. "Investigation into primary septicaemic infections caused by Escherichia coli strains in chickens." Thesis, Queen's University Belfast, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.437481.

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25

Synge, Barti Arnold. "Epidemiological studies of verocytotoxin-producing Escherichia coli infections in animals in Scotland." Thesis, University of Edinburgh, 2006. http://hdl.handle.net/1842/30813.

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This thesis is a summation of studies carried out between 1991 and 2004 and attempts to place the work in context with other knowledge to establish the role of animals as a source of human infection with verocytotoxin-producing <i>Escherichia coli </i>(VTEC). VTEC O157 was first isolated from cattle in Scotland in 1992. In a preliminary prevalence study using basic techniques to examine faeces sample routinely submitted to the Scottish Agricultural College (SAC) Veterinary Centres, 0.25% samples from cattle were positive for VTEC O157. The organism was more commonly isolated from calves less t
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26

Canhizares, Thaisy Milanelli [UNESP]. "O papel da Escherichia coli na retocolite ulcerativa." Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/151404.

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Canhizares, Thaisy Milanelli. "O papel da Escherichia coli na retocolite ulcerativa." Botucatu, 2017. http://hdl.handle.net/11449/151404.

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Orientador: Josias Rodrigues<br>Resumo: Retocolite Ulcerativa (RU) é um tipo de patologia que acomete o cólon intestinal, se apresentando na forma de lesões superficiais de gravidade variável. Não possui causa definida, mas sabe-se que é influenciada por fatores genéticos e ambientais, na qual, esse último, inclui um desequilíbrio na composição de espécies da microbiota intestinal. Escherichia coli (E. coli), uma das bactérias que se encontra aumentada nesses pacientes, tem sido foco de estudos de caracterização, com o objetivo de esclarecer sua participação na etiologia ou complicação dos sin
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Choi, Suk Ho. "Binding mechanism of K88ab pili produced by enterotoxigenic Escherichia coli." Diss., Virginia Polytechnic Institute and State University, 1987. http://hdl.handle.net/10919/74764.

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Binding of K88ab pili by brush border membrane and mucus from pig small intestine was characterized by inhibition assay and Western blot. In Western blot, K88ab pili were bound by two major brush border membrane polypeptides with molecular weight of 61,500 and 57,000 in addition to numerous minor polypeptides and a major mucus polypeptide with molecular weight of 27,500. The results from Western blot assays with periodate oxidized and carbamylated brush border membrane and inhibition assay with brush border membrane glycopeptide suggest that amino groups (rather than carbohydrate) present on t
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29

Chen, Ming. "Renal cell death in urinary tract infections : role of E. coli toxins /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-166-0/.

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30

Dahan, Stéphanie. "Effets et mécanismes de protection de saccharomyces boulardii vis-à-vis des infections intestinales causées par escherichia coli entéropathogène et escherichia coli entérohémorragiques." Aix-Marseille 3, 2002. http://www.theses.fr/2002AIX30059.

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SACCHAROMYCES BOULARDII (S. B. ) EST UNE LEVURE ADMINISTREE POUR SES PROPRIETES ANTI-DIARRHEIQUES. LES DIARRHEES A ESCHERICHIA COLI ENTEROPATHOGENES (EPEC) SONT FREQUENTES CHEZ LES ENFANTS DES PAYS EN VOIE DE DEVELOPPEMENT. L'INFECTION PAR EPEC PROVOQUE LA DESTRUCTION DE LA MUQUEUSE INTESTINALE ET UNE REPONSE INFLAMMATOIRE CONDUISANT A UNE DIARRHEE AQUEUSE PERSISTANTE POUVANT ENTRAINER LA MORT. LES ESCHERICHIA COLI ENTEROHEMORRAGIQUES (EHEC) SONT DEVENUES EN QUELQUES ANNEES UNE MENACE POUR LES PAYS DEVELOPPES. ELLES FAVORISENT LA SURVENUE SURTOUT CHEZ LES ENFANTS ET LES SUJETS AGES DE COLITES
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31

Takahashi, Akira. "Molecular epidemiological studies of Escherichia coli isolates obtained from lower urinary tract infections." Kyoto University, 2010. http://hdl.handle.net/2433/120579.

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32

Alhashash, F. A. "Populations of Escherichia coli in clinical samples of urinary tract infections and bacteraemia." Thesis, Nottingham Trent University, 2015. http://irep.ntu.ac.uk/id/eprint/27939/.

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Extraintestinal pathogenic E. coli (ExPEC) strains are the main etiologic agent of urinary tract infections (UTIs). ExPEC strains are also reported to be the most common cause of bacteraemia in the world, which often originate from UTI. The population structure of UTI E. coli strains is well described in the literature with increased prevalence of multidrug resistance driven by extended spectrum β lactamases (ESBLs). ESBL carriage and multidrug resistance of bacteraemia E. coli is on the increase yet little information is available about their population structure. With the aim to define the b
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33

Nicklasson, Matilda. "Studies on the expression and regulation of enterotoxins and colonization factors in enterotoxigenic Escherichia coli (ETEC) /." Göteborg : Institute of Biomedicine, Dept. of Microbiology and immunology, Göteborg University, 2008. http://hdl.handle.net/2077/9610.

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34

Levert, Maxime. "Compréhension de la diversité génotypique et phénotypique générée chez Escherichia coli lors des infections extraintestinales." Paris 5, 2010. http://www.theses.fr/2010PA05S002.

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Ce travail a consisté à obsever et étudier les mécanismes responsable de la diversification génotypique et phénotypiques des clones d'E. Coli lors des infections extraintestinales. Plusieurs polymorphismes phénotypiques s'expliquent par des niveaux différents de la protéine RpoS dans les isolats. L'étude fine des isolats d'un patient n'a pas permis de détecter de mutations dans le gène RpoS mais le séquençage de quatre de ces souches a permis de découvrir au moins six mutations ponctuelles, une délétion et une insertion d'élément IS;. La moitié présentant un lien direct avec l'expression de ce
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Miranda, Regina L. "The role of glycolytic substrates in the initiation and maintenance phases of colonization of the mouse large intestine by Escherichia coli MG1655 and Escherichia coli EDL933 /." View online ; access limited to URI, 2004. http://0-wwwlib.umi.com.helin.uri.edu/dissertations/dlnow/3147802.

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Farra, Anna. "Antibiotic resistance and antibiotic consumption in Sweden with focus on Escherichia coli and Pseudomonas aeruginosa /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-201-9/.

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Bernier-Febreau, Christine. "Identification et caractérisation de facteurs de pathogénicité produits par les Escherichia coli entéroagrégatifs." Paris 7, 2003. http://www.theses.fr/2003PA077012.

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Tahoun, Amin M. Abd El Hady. "Role of Type III secretory effectors EspF and SopB in enteric pathogenesis of Escherichia coli and Salmonella enterica serovar Typhimurium." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5899.

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The EspF protein is translocated into host cells by the type III secretion system of enteropathogenic and enterohemorrhagic Escherichia coli (EPEC and EHEC). EspF sequences differ between EPEC and EHEC serotypes in terms of the number of SH3-binding polyproline rich repeats and specific residues in these regions as well as residues in the amino domain involved in cellular localization. In this study we have compared the capacity of different espF alleles to inhibit: (i) bacterial phagocytosis by macrophages; (ii) translocation through an M-cell co-culture system; (iii) uptake by and translocat
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Valério, Nádia Castanho. "Potential effects between bacteriophages and antibiotics to inactivate Escherichia coli." Master's thesis, Universidade de Aveiro, 2016. http://hdl.handle.net/10773/22360.

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Mestrado em Microbiologia<br>Escherichia coli is part of the normal flora of the gastrointestinal tract of humans and various mammals. This opportunistic microorganism is capable of cause several infections, such as urinary tract infections (UTI). E. coli is resistant to a large number of antibiotics, becoming harder the control of infections caused by this bacterium. Phage therapy may be a useful tool to control infections caused by antibiotic resistant strains. However, the major concern of the phage therapy is also the emergence of phage resistant bacteria. In this study, was evaluated the
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Rivera, Hector. "Cloning and immunogenicity of a Chlamydia Trachomatis 36 kilodalton recombinant gene product in Escherichia Coli." CSUSB ScholarWorks, 1991. https://scholarworks.lib.csusb.edu/etd-project/839.

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Barletta, Francesca, Theresa J. Ochoa, Erik H. Mercado, Joaquim Ruiz, Lucie Ecker, Giovanni Lopez, Monica Mispireta, Ana I. Gil, Claudio F. Lanata, and Thomas G. Cleary. "Quantitative real-time polymerase chain reaction for enteropathogenic Escherichia coli: a tool for investigation of asymptomatic versus symptomatic infections." Oxford University Press, 2015. http://hdl.handle.net/10757/556075.

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theresa.j.ochoa@uth.tmc.edu<br>Article<br>BACKGROUND: Enteropathogenic Escherichia coli (EPEC) strains are pediatric pathogens commonly isolated from both healthy and sick children with diarrhea in areas of endemicity. The aim of this study was to compare the bacterial load of EPEC isolated from stool samples from children with and without diarrhea to determine whether bacterial load might be a useful tool for further study of this phenomenon. METHODS: EPEC was detected by polymerase chain reaction (PCR) of colonies isolated on MacConkey plates from 53 diarrheal and 90 healthy children aged
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Khandaker, MD Shahjahan Ali. "Economic analysis of diseases caused by VTEC (verotoxin producing e.coli) in Australia /." St. Lucia, Qld, 2002. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe17335.pdf.

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43

Horvath, Dennis John Jr. "The Impact of Phagocyte-UPEC Interactions Upon Pathogenesis of Urinary Tract Infections." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1316282102.

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44

Lai, YuShuan (Cindy). "EspFU, an Enterohemorrhagic E. Coli Secreted Effector, Hijacks Mammalian Actin Assembly Proteins by Molecular Mimicry and Repetition: A Dissertation." eScholarship@UMMS, 2014. https://escholarship.umassmed.edu/gsbs_diss/715.

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Enterohemorrhagic E. coli (EHEC) is a major cause of food borne diarrheal illness worldwide. While disease symptoms are usually self-resolving and limited to severe gastroenteritis with bloody diarrhea, EHEC infection can lead to a life threatening complication known as Hemolytic Uremic Syndrome (HUS), which strikes children disproportionately and is the leading cause of kidney failure in children. Upon infection of gut epithelia, EHEC produces characteristic lesions called actin pedestals. These striking formations involve dramatic rearrangement of host cytoskeletal proteins. EHEC hijacks mam
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Lai, YuShuan (Cindy). "EspFU, an Enterohemorrhagic E. Coli Secreted Effector, Hijacks Mammalian Actin Assembly Proteins by Molecular Mimicry and Repetition: A Dissertation." eScholarship@UMMS, 2004. http://escholarship.umassmed.edu/gsbs_diss/715.

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Enterohemorrhagic E. coli (EHEC) is a major cause of food borne diarrheal illness worldwide. While disease symptoms are usually self-resolving and limited to severe gastroenteritis with bloody diarrhea, EHEC infection can lead to a life threatening complication known as Hemolytic Uremic Syndrome (HUS), which strikes children disproportionately and is the leading cause of kidney failure in children. Upon infection of gut epithelia, EHEC produces characteristic lesions called actin pedestals. These striking formations involve dramatic rearrangement of host cytoskeletal proteins. EHEC hijacks mam
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46

Privat, Pascale. "Anguillulose maligne et méningites récidivantes à escherichia coli dans le cadre d'un syndrome d'immunodéficience acquise." Montpellier 1, 1993. http://www.theses.fr/1993MON11193.

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47

Salo, J. (Jarmo). "Long-term consequences and prevention of urinary tract infections in childhood." Doctoral thesis, Oulun yliopisto, 2012. http://urn.fi/urn:isbn:9789514298707.

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Abstract Urinary tract infections (UTIs) are among the most common bacterial infections in childhood and have a tendency to recur. The ability of uropathogens to form biofilm may be important in the pathogenesis of UTI. Although childhood UTIs are thought to increase the risk of chronic kidney disease (CKD), evidence showing this association is scarce. Cranberry juice has been shown to prevent UTIs in women, but evidence of its efficacy in children is lacking. The aim of this work was to evaluate the significance of biofilm formation for the clinical presentation of UTI, the long-term conseque
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48

Hagman, Ragnvi. "New aspects of canine pyometra : studies on epidemiology and pathogenesis /." Uppsala : Dept. of Small Animal Clinical Sciences, Swedish Univ. of Agricultural Sciences, 2004. http://epsilon.slu.se/v182.pdf.

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49

Wetzel, Amy Noel. "Studies in Shiga toxin-producing Escherichia coli O157:H7 determination of factors contributing to the dissemination of Escherichia coli O157:H7 among dairy farms /." Columbus, Ohio : Ohio State University, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1133239436.

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50

Chapman, Peter Alan. "Purification of the verotoxins of Escherichia coli and production of antitoxins for use in a diagnostic test." Thesis, University of Sheffield, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244433.

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