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Relevant bibliographies by topics / Esophagus Squamous cell carcinoma Gene expression

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Academic literature on the topic 'Esophagus Squamous cell carcinoma Gene expression'

Author: Grafiati

Published: 4 June 2021

Last updated: 15 February 2022

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Journal articles on the topic "Esophagus Squamous cell carcinoma Gene expression"

1

van Baal, Jantine W. P. M., Francesco Milana, Agnieszka M. Rygiel, et al. "A comparative Analysis by SAGE of Gene Expression Profiles of Esophageal Adenocarcinoma and Esophageal Squamous Cell Carcinoma." Analytical Cellular Pathology 30, no. 1 (2008): 63–75. http://dx.doi.org/10.1155/2008/328529.

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Esophageal adenocarcinoma (EA) and esophageal squamous cell carcinoma (ESCC) are the two main types of esophageal cancer. Despite extensive research the exact molecular basis of these cancers is unclear. Therefore we evaluated the transcriptome of EA in comparison to non-dysplastic Barrett’s esophagus (BE), the metaplastic epithelium that predisposes for EA, and compared the transcriptome of ESCC to normal esophageal squamous epithelium. For obtaining the transcriptomes tissue biopsies were used and serial analysis of gene expression (SAGE) was applied. Validation of results by RT-PCR and immu

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Lu, Jiayun, Zhihua Liu, Momiao Xiong, et al. "Gene expression profile changes in initiation and progression of squamous cell carcinoma of esophagus." International Journal of Cancer 91, no. 3 (2001): 288–94. http://dx.doi.org/10.1002/1097-0215(200002)9999:9999<::aid-ijc1063>3.0.co;2-s.

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Terayama, Masayoshi, Teruki Hagiwara, Kazuhiko Yamada, et al. "PS02.048: DECREASED EXPRESSION OF PRSS27 IN ESOPHAGEAL SQUAMOUS CELL CARCINOMA." Diseases of the Esophagus 31, Supplement_1 (2018): 134. http://dx.doi.org/10.1093/dote/doy089.ps02.048.

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Abstract Background Alcohol drinking and smoking are substantial risk factors of esophageal squamous cell carcinoma (ESCC) and are supposed to induce genetic mutations and epigenetic disorders, including aberrant DNA methylation. Previously, we have conducted transcriptome and methylome analyses of a paired specimen of ESCC and adjacent non-cancerous tissues and found that both gene expression and promotor methylation of PRSS27 were perturbed in ESCC. PRSS27 was a trypsin-like serine protease (also known as marapsin) and expressed in normal esophagus; however, little is known about the signifi

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Kajiwara, T., T. Nishina, I. Hyodo, et al. "Impact of gene expression of orotate phosphoribosyl transferase for complete response to chemoradiotherapy in patients with squamous cell carcinoma of the esophagus." Journal of Clinical Oncology 25, no. 18_suppl (2007): 4566. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.4566.

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4566 Background: Chemoradiotherapy (CRT) is a potential alternative to surgery in patients with squamous cell carcinoma of the esophagus. Complete response (CR) to CRT is essential for a good prognosis and there is a need for a predictive method of CR in CRT. Methods: The pretreatment formalin-fixed, paraffin-embedded endoscopic tumor biopsy material was obtained from 41 patients treated with a definitive concurrent CRT (5-FU/CDDP and 60 Gy) for esophageal cancer (cStage II or III). cDNA was derived from tumor cells of biopsy specimens by the laser capture microdissection and analyzed to deter

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Chen, Shirui, Kai Zhou, Liguang Yang, Guohui Ding, and Hong Li. "Racial Differences in Esophageal Squamous Cell Carcinoma: Incidence and Molecular Features." BioMed Research International 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/1204082.

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The incidence and histological type of esophageal cancer are highly variable depending on geographic location and race/ethnicity. Here we want to determine if racial difference exists in the molecular features of esophageal cancer. We firstly confirmed that the incidence rate of esophagus adenocarcinoma (EA) was higher in Whites than in Asians and Blacks, while the incidence of esophageal squamous cell carcinoma (ESCC) was highest in Asians. Then we compared the genome-wide somatic mutations, methylation, and gene expression to identify differential genes by race. The mutation frequencies of s

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Greenawalt, Danielle M., Cuong Duong, Gordon K. Smyth, et al. "Gene expression profiling of esophageal cancer: Comparative analysis of Barrett's esophagus, adenocarcinoma, and squamous cell carcinoma." International Journal of Cancer 120, no. 9 (2007): 1914–21. http://dx.doi.org/10.1002/ijc.22501.

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Tada, Takeshi, Reiko Honma, Jun-Ichi Imai, et al. "A novel gene expression scoring system for accurate diagnosis of basaloid squamous cell carcinoma of the esophagus." International Journal of Oncology 51, no. 3 (2017): 877–86. http://dx.doi.org/10.3892/ijo.2017.4075.

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Zhou, Yalu, Joel L. Schwartz, Saurabh Sinha, Ardaman Shergill, and Guy Adami. "A large subtype of squamous cell carcinoma enriched for TrkB-T1 mRNA." Journal of Clinical Oncology 37, no. 15_suppl (2019): e14751-e14751. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e14751.

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e14751 Background: A large subtype of squamous cell carcinoma enriched for TrkB-T1 mRNA. Background The NTRK2 genetic locus encodes neurotrophin membrane receptors that play an important role in normal neural tissue plasticity, growth, and survival. One NTRK2-encoded protein is TrkB-FL, which can regulate multiple pathways relevant to cancer. A second NTRK2 gene mRNA isoform encodes TrkB-T1, a receptor that has a different cytoplasmic domain and is encoded in a mRNA with a unique 3’ terminal exon. Methods: Tumors from The Cancer Genome Atlas (TCGA) and other studies were classified according t

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Hibino, Soki, Mitsuro Kanda, Hisaharu Oya, et al. "Reduced expression of DENND2D through promoter hypermethylation as an adverse prognostic factor in squamous cell carcinoma of the esophagus." Journal of Clinical Oncology 32, no. 3_suppl (2014): 58. http://dx.doi.org/10.1200/jco.2014.32.3_suppl.58.

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58 Background: Esophageal cancer ranks sixth in cancer mortality worldwide and patients with ESCC have a poor prognosis with a 5-year survival rate of less than 10%. Elucidation of the mechanisms of carcinogenesis and tumor progression in esophageal cancer is urgently needed to develop targets for therapy and prognostic biomarkers. In the present study, the expression and regulatory mechanism of the Differentially Expressed in Normal and Neoplastic cells Domain containing 2D (DENND2D), which is a regulator of Rab GTPases, were investigated to explore its potential as a tumor suppressor gene fo

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Ojima, Toshiyasu, Mikihito Nakamori, Masaki Nakamura, et al. "Expression of ERCC1, TUBB3, BRCA1, and TS as predictive markers of neoadjuvant chemotherapy for squamous cell carcinoma of the esophagus." Journal of Clinical Oncology 34, no. 4_suppl (2016): 47. http://dx.doi.org/10.1200/jco.2016.34.4_suppl.47.

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47 Background: No predictive biomarker of the response to neoadjuvant chemotherapy with docetaxel and cisplatin plus 5-fluorouracil (NAC-DCF) is available for patients with squamous cell carcinoma of the esophagus (SCCE) in a clinical setting. The aim of this study was to identify the biomarkers associated with chemotherapeutic efficacy and long-term survival for patients with advanced SCCE who had received NAC-DCF followed by surgery. Methods: This study included 45 patients with advanced SCCE who received NAC-DCF between January 2008 and December 2012. The NAC-DCF was conducted as a phase II

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Dissertations / Theses on the topic "Esophagus Squamous cell carcinoma Gene expression"

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Cheung, Chi-man. "Identification of differentially expressed genes in a newly established esophageal squamous cell carcinoma(ESCC) cell line HKESC-4 of Chinese origin." View the Table of Contents & Abstract, 2007. http://sunzi.lib.hku.hk/hkuto/record/B3971102X.

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Leung, Cheuk-man, and 梁卓文. "A study of BARX2 expression in esophageal squamous cell carcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B47560460.

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Background Esophageal carcinoma mainly affects middle aged to elderly males. It ranks the ninth most common cancer world-wide. The main histological types are squamous cell carcinoma and adenocarcinoma. In Hong Kong, esophagus squamous cell carcinoma (ESCC) is by far the more common. BARX2 is a human homeobox gene located at 11q24-q25, encoding a protein of 254 amino acids. Recent researches show that its expression in breast cancer promotes cellular invasion. Objectives The study aimed to test the hypothesis that BARX2 is a prognostic marker in ESCC. BARX2 expression in ESCC was c

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Cheung, Chi-man, and 張志文. "Identification of differentially expressed genes in a newly established esophageal squamous cell carcinoma(ESCC) cell line HKESC-4of Chinese origin." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B39793722.

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Kwong, Fung Mei. "Investigation of a known tumor suppressor gene, p161NK4a, in human esophageal squamous cell carcinoma cell lines /." View Abstract or Full-Text, 2003. http://library.ust.hk/cgi/db/thesis.pl?BIOL%202003%20KWONG.

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Thesis (M. Phil.)--Hong Kong University of Science and Technology, 2003.<br>Includes bibliographical references (leaves 74-87). Also available in electronic version. Access restricted to campus users.

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Zhang, Liyi, and 張麗儀. "Identification and characterization of tumor suppressor gene and cancer stemness gene in esophageal squamous cell carcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2015. http://hdl.handle.net/10722/208563.

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Esophageal squamous cell carcinoma (ESCC), the major histological subtype of esophageal cancer, is one of the most common malignancies with poor prognosis in the world. Despite continued development of diagnosis and treatment, ESCC remains the sixth leading cause of cancer death worldwide. Current treatment regimens in ESCC are often characterized by ineffectiveness and poor selectivity. Therapeutic methods directed at cancer-associated genes or cancer stem cells (CSCs) may be effective approaches to cure this deadly cancer. Therefore, this study aims to identify specific ESCC-related genes an

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Fu, Li, and 付利. "Identification and characterization of cancer-related genes in esophageal squamous cell carcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B39557820.

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Nkosi, Cornelius Muzi. "The expression of E-cadherin and β-catenin in squamous cell carcinoma of the esophagus". Thesis, University of Limpopo ( Medunsa Campus), 2010. http://hdl.handle.net/10386/418.

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Thesis (M Med (Anatomical Pathology))--University of Limpopo, 2010.<br>Background Esophageal squamous cell carcinoma (SCC) remains a disease of poor prognosis. Early diagnosis is compromised by the delayed onset of symptoms. By the time of surgical intervention metastases and organ infiltration have already occurred this reduces the prognosis significantly and the 5-year survival rate of operative advanced esophageal SCC remains poor. In order to select an appropriate therapeutic regime and guard against both over- and under treatment, reproducible prognostic markers are needed at the time of

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Kong, Kar-lok, and 江家樂. "Identification and characterization of tumor suppressive gene and microRNA in esophageal squamous cell carcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46455693.

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Serewko-Auret, Magdalena M. "Alterations in gene expression and activity during squamous cell carcinoma development /." [St. Lucia, Qld.], 2002. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe17158.pdf.

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Brownlie, Laura. "Differential gene expression studies in non-melanoma skin cancer." Thesis, University of Newcastle Upon Tyne, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323449.

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Book chapters on the topic "Esophagus Squamous cell carcinoma Gene expression"

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Patowary, Pallabi, and Dhruba K. Bhattacharyya. "Crucial Gene Identification for Esophageal Squamous Cell Carcinoma Using Differential Expression Analysis." In Communications in Computer and Information Science. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-6318-8_35.

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2

Barbosa, Fernanda Correia, Joel P. Arrais, and José Luís Oliveira. "Weighted Gene Co-expression Network Analysis Applied to Head and Neck Squamous Cell Carcinoma Data." In IFMBE Proceedings. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-03005-0_76.

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Rischin, Danny. "Biomarkers for Immune Modulatory Treatment in Head and Neck Squamous Cell Carcinoma (HNSCC)." In Critical Issues in Head and Neck Oncology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-63234-2_6.

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AbstractImmune checkpoint inhibitors have changed the standard of care for recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC). However, only a minority of patients respond, hence the search for predictive biomarkers. Potential predictive biomarkers for immune checkpoint inhibitors discussed in this chapter include (1) Immune checkpoint ligand expression e.g., PD-L1, (2) biomarkers of a T-cell inflamed tumour microenvironment (TME) such as gene expression profiles of activated T cells, (3) biomarkers of tumour neoepitope burden such as tumour mutation burden (TMB) and (4) multidimensional quantitative techniques. At present only PD-L1 expression has been shown to have clinical utility in head and neck cancer. It enriches for populations more likely to respond, but the false positive predictive value remains high. In the pivotal Keynote−048 trial that established a role for pembrolizumab (anti-PD1) monotherapy and pembrolizumab + chemotherapy as treatment options in first-line R/M HNSCC, primary endpoints included overall survival in defined subgroups based on PD-L1 expression. In this trial the combined positive score (CPS) was used which takes into account PD-L1 expression in tumour and immune cells. Based on this trial regulatory approvals for first-line pembrolizumab in R/M HNSCC require assessment of PD-L1 expression using the CPS. Finally we discuss emerging evidence that locoregionally advanced HPV-associated oropharyngeal cancers that have high expression of CD103 positive CD8 T cells have an excellent prognosis and features that suggest increased probability of responding to anti-PD1/PD-L1, raising the possibility of incorporating these immune therapies as part of a de-escalation trial strategy.

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Shintani, Satoru. "Genome-Wide cDNA Microarray Screening of Gene Expression Profiles Correlated with Resistance to Anti-Cancer Drug Treatment and Radiation in Oral Squamous Cell Carcinoma." In New Trends in the Molecular and Biological Basis for Clinical Oncology. Springer Japan, 2009. http://dx.doi.org/10.1007/978-4-431-88663-1_12.

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Ramadoss, Ramya, Rajkumar Krishnan, Lekshmy Jayan, and Priyadharini Shankaran. "RNA Sequencing in Potentially Malignant Disorders." In Applications of RNA-Seq in Biology and Medicine [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.97712.

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RNA sequencing is a molecular technique which utilizes next generation sequencing to identify and quantify ribonucleic acid (RNA) in a given sample. This technique is utilized in the detection of changes in gene expression. Potentially malignant oral disorders are one of the most troublesome lesions seen in the oral cavity which predisposes to the development of oral cancer. Though there are many methods employed in the diagnosis of these disorders, biopsy followed by histological examination is the gold standard procedure followed in the diagnosis. RNA sequencing has been receiving attention among researchers. Many studies have been conducted to analyze the application of RNA sequencing in the diagnosis of PMODs as well as in the malignant transformation to oral squamous cell carcinoma. The article attempts to summarize the progress in RNA sequencing pertaining to Potentially malignant disorders.

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Conference papers on the topic "Esophagus Squamous cell carcinoma Gene expression"

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Sakamoto, Naoya, Naohide Oue, Tsuyoshi Noguchi, et al. "Abstract 2178: Serial analysis of gene expression (SAGE) of esophageal squamous cell carcinoma: ADAMTS-16 is up-regulated in esophageal squamous carcinoma." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-2178.

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Hauser, Belinda, Yubin Hao, Xinbin Gu, and Joseph Califano. "Abstract B40: micro-RNA-128 regulated gene expression in head and neck squamous cell carcinoma." In Abstracts: AACR International Conference on the Science of Cancer Health Disparities‐‐ Sep 18-Sep 21, 2011; Washington, DC. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1055-9965.disp-11-b40.

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Wong, Jackson, Dana Gaffney, Michael Sharp, et al. "Abstract 4666: Profiling mesothelin protein expression by immunohistochemistry and gene expression in adenocarcinoma and squamous cell carcinoma of lung." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-4666.

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Kant, Nimita, and Perumal Senthiappan Jayaraj. "Evaluation of Telomerase Reverse Transcriptase Expression in Squamous Cell Carcinoma of the Skin." In Annual Conference of Indian Society of Medical and Paediatric Oncology (ISMPO). Thieme Medical and Scientific Publishers Pvt. Ltd., 2021. http://dx.doi.org/10.1055/s-0041-1735375.

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Abstract Introduction Squamous cell carcinoma (SCC) is highly invasive malignant tumor showing keratinocytic differentiation and is often associated with chronic exposure to UV light. Telomerase is RNA dependent DNA polymerase that causes addition of telomeric repeat DNA sequences to chromosomal ends. Recently, UV signature mutations have been identified in core promoter region of TERT gene, which encodes the main catalytic subunit leading to overexpression in cutaneous melanoma. However, its role and expression pattern have not been studied in eyelid skin SCC. Objectives Present study aimed t

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Nakajima, Takako Eguchi, Hiroshi Yoshida, Hirokazu Taniguchi, Kenkichi Masutomi, Tadakazu Shimoda, and Yasuhide Yamada. "Abstract 3361: Immunohistochemical analysis of CD133/44 expression in surgical specimens of squamous cell carcinoma of the esophagus after neoadjuvant chemotherapy." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-3361.

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Mayhew, Gregory, Chuck Perou, D. Neil Hayes, Myla Lai-Goldman, and Hawazin Faruki. "Abstract A037: Differences in BRCAness/PARP inhibitor response signatures and homologous recombination gene expression across lung adenocarcinoma and squamous cell carcinoma gene expression subtypes." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; October 26-30, 2017; Philadelphia, PA. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1535-7163.targ-17-a037.

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Zhang, Mingxin, Ning Lu, Qian Li, and Manli Cui. "IDDF2021-ABS-0106 Significance of the expression of iron death-related gene hsbp1 in esophageal squamous cell carcinoma." In Abstracts of the International Digestive Disease Forum (IDDF), Hong Kong, 4–5 September 2021. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2021. http://dx.doi.org/10.1136/gutjnl-2021-iddf.38.

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Flam, Emily L., Dylan Z. Kelley, Elena Stavrovskaya, et al. "Abstract 364: Differentially methylated super-enhancers regulate gene expression in human papillomavirus-related head and neck squamous cell carcinoma." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-364.

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Xiong, Donghai, Jing Pan, Qi Zhang, et al. "Abstract 2423: Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-2423.

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Ezic, J., A. von Witzleben, A. Fehn, et al. "RNA-sequencing reveals an immune “hot” gene expression signature in oropharyngeal squamous cell carcinoma which is upregulated upon decitabine treatment in cell lines." In 100 JAHRE DGHNO-KHC: WO KOMMEN WIR HER? WO STEHEN WIR? WO GEHEN WIR HIN? Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1727963.

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