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Journal articles on the topic 'Estimation de Kaplan-Meier'

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Published: 4 June 2021

Last updated: 17 February 2022

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1

Ozguven, Eren Erman, and Kaan Ozbay. "Nonparametric Bayesian Estimation of Freeway Capacity Distribution from Censored Observations." Transportation Research Record: Journal of the Transportation Research Board 2061, no. 1 (2008): 20–29. http://dx.doi.org/10.3141/2061-03.

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Previous studies have been made of the usefulness and effectiveness of survival analysis in transportation and traffic engineering studies with incomplete data in which the Kaplan–Meier estimate is proposed for determining traffic capacity distribution. However, well-known estimators like Kaplan–Meier and Nelson–Aalen have several disadvantages that make it difficult to obtain the traffic capacity distribution. First, neither estimator is defined for all values of traffic flows possible. That is, the maximum flow followed by a breakdown defines the final point of the estimated distribution cur

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2

Khan, Md Hasinur Rahaman, and J. Ewart H. Shaw. "Robust bias estimation for Kaplan–Meier survival estimator with jackknifing." Journal of Statistical Theory and Practice 10, no. 1 (2015): 7–19. http://dx.doi.org/10.1080/15598608.2015.1062833.

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Kim, Choongrak, Whasoo Bae, Hyemi Choi, and Byeong U. Park. "Non-parametric hazard function estimation using the Kaplan–Meier estimator." Journal of Nonparametric Statistics 17, no. 8 (2005): 937–48. http://dx.doi.org/10.1080/10485250500337138.

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4

Dhar, D. "Estimation of Survival Function Under Random Censorship." Calcutta Statistical Association Bulletin 42, no. 1-2 (1992): 75–86. http://dx.doi.org/10.1177/0008068319920105.

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The paper deals with the estimation of survival function of a particular random variable of interest in proportional hazard model of random censorship under the condition that data are randomly censored by k independent variables. Estimators are constructed using results from Abdushukurov (1984), Cheng and Lin (1984), Ebrahimi (1985) and Kaplan and Meier (1958). The asymptotic behaviour of all these estimators is investigated. Numerical results are provided to calculate the efficiencies of ACL and Ebrahimi's estimators in comparsion to classical Kaplan-Meier (1958) estimator.

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Nematolahi, Samane, Sahar Nazari, Zahra Shayan, Seyyed Mohammad Taghi Ayatollahi, and Ali Amanati. "Improved Kaplan-Meier Estimator in Survival Analysis Based on Partially Rank-Ordered Set Samples." Computational and Mathematical Methods in Medicine 2020 (May 31, 2020): 1–11. http://dx.doi.org/10.1155/2020/7827434.

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This study presents a novel methodology to investigate the nonparametric estimation of a survival probability under random censoring time using the ranked observations from a Partially Rank-Ordered Set (PROS) sampling design and employs it in a hematological disorder study. The PROS sampling design has numerous applications in medicine, social sciences and ecology where the exact measurement of the sampling units is costly; however, sampling units can be ordered by using judgment ranking or available concomitant information. The general estimation methods are not directly applicable to the cas

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Prentice, Ross L., and Shanshan Zhao. "Nonparametric estimation of the multivariate survivor function: the multivariate Kaplan–Meier estimator." Lifetime Data Analysis 24, no. 1 (2016): 3–27. http://dx.doi.org/10.1007/s10985-016-9383-y.

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7

Wu, Qunying, and Pingyan Chen. "A Berry-Esseen Type Bound in Kernel Density Estimation for Negatively Associated Censored Data." Journal of Applied Mathematics 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/541250.

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We discuss the kernel estimation of a density function based on censored data when the survival and the censoring times form the stationary negatively associated (NA) sequences. Under certain regularity conditions, the Berry-Esseen type bounds are derived for the kernel density estimator and the Kaplan-Meier kernel density estimator at a fixed pointx.

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Hansen, Martin B., and Erik W. van Zwet. "Nonparametric estimation of the chord length distribution." Advances in Applied Probability 33, no. 03 (2001): 541–58. http://dx.doi.org/10.1017/s0001867800010983.

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The distribution of the length of a typical chord of a stationary random set is an interesting feature of the set's whole distribution. We give a nonparametric estimator of the chord length distribution and prove its strong consistency. We report on a simulation experiment in which our estimator compared favourably to a reduced sample estimator. Both estimators are illustrated by applying them to an image sample from a yoghurt ferment. We briefly discuss the closely related problem of estimation of the linear contact distribution. We show by a simulation experiment that a transformation of our

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Hansen, Martin B., and Erik W. van Zwet. "Nonparametric estimation of the chord length distribution." Advances in Applied Probability 33, no. 3 (2001): 541–58. http://dx.doi.org/10.1239/aap/1005091351.

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The distribution of the length of a typical chord of a stationary random set is an interesting feature of the set's whole distribution. We give a nonparametric estimator of the chord length distribution and prove its strong consistency. We report on a simulation experiment in which our estimator compared favourably to a reduced sample estimator. Both estimators are illustrated by applying them to an image sample from a yoghurt ferment. We briefly discuss the closely related problem of estimation of the linear contact distribution. We show by a simulation experiment that a transformation of our

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10

CAMPIGOTTO, F., D. NEUBERG, and J. I. ZWICKER. "Biased estimation of thrombosis rates in cancer studies using the method of Kaplan and Meier." Journal of Thrombosis and Haemostasis 10, no. 7 (2012): 1449–51. http://dx.doi.org/10.1111/j.1538-7836.2012.04766.x.

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11

Calabuig, Jose M., Luis M. García-Raffi, Albert García-Valiente, and Enrique A. Sánchez-Pérez. "Evolution Model for Epidemic Diseases Based on the Kaplan-Meier Curve Determination." Mathematics 8, no. 8 (2020): 1260. http://dx.doi.org/10.3390/math8081260.

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We show a simple model of the dynamics of a viral process based, on the determination of the Kaplan-Meier curve P of the virus. Together with the function of the newly infected individuals I, this model allows us to predict the evolution of the resulting epidemic process in terms of the number E of the death patients plus individuals who have overcome the disease. Our model has as a starting point the representation of E as the convolution of I and P. It allows introducing information about latent patients—patients who have already been cured but are still potentially infectious, and re-infect

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12

Pawlas, Zbynek, and Marketa Zikmundova. "A COMPARISON OF NONPARAMETRIC ESTIMATORS FOR LENGTH DISTRIBUTION IN LINE SEGMENT PROCESSES." Image Analysis & Stereology 38, no. 2 (2019): 121. http://dx.doi.org/10.5566/ias.1889.

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We study nonparametric estimation of the length distribution for stationary line segment processes in the d-dimensional Euclidean space. Several methods have been proposed in the literature. We review different approaches (Horvitz-Thompson type estimator, reduced-sample estimator, Kaplan-Meier estimator, nonparametric maximum likelihood estimator, stochastic restoration estimation) and compare the finite sample behaviour by means of a simulation study for stationary line segment processes in 2D and 3D. Several data generating processes (Poisson point process, Matérn cluster process and Matérn

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13

Mansmann, U. "The Arithmetics of Risk." Interventional Neuroradiology 3, no. 1 (1997): 43–47. http://dx.doi.org/10.1177/159101999700300105.

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In the following note the basic principles of event data analysis and censored data will be explained. The concept of risk will be defined. The interaction of estimation and confidence interval will be discussed. We explain the estimator of risk and show how to use it for the calculation of probability statements. An example is given to make the formal statements more explicit. We define the Kaplan-Meier estimator and compare it to the risk concept. Two common fallacies in risk assessment are discussed.

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Habibah, Immawati Ainun, Tatik Widiharih, and Suparti Suparti. "KETAHANAN HIDUP PASIEN GAGAL GINJAL DENGAN METODE KAPLAN MEIER (Studi Kasus di Rumah Sakit Umum Daerah dr. R. Soedjati Soemodiarjo Purwodadi)." Jurnal Gaussian 7, no. 3 (2018): 270–80. http://dx.doi.org/10.14710/j.gauss.v7i3.26660.

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Chronic Kidney Disease (CKD) is a failure of kidney function that which get slowly and can not recover. Most of the patients CKD get death sudden becuse of cardiovascular complications (related to the heart and blood vessels) however only minor part can reach terminal phase (CKD stage 5) which need replacement therapy of Kidney. Replacement therapy of Kidney are hemodialysis, peritoneal dialysis, and Kidney transplant. Because of that, the importance to study how long the patient opportunity is life endurance analysis. Survival analysis methods to life depend from the life time and status of i

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Lo, S. H., Y. P. Mack, and J. L. Wang. "Density and hazard rate estimation for censored data via strong representation of the Kaplan-Meier estimator." Probability Theory and Related Fields 80, no. 3 (1989): 461–73. http://dx.doi.org/10.1007/bf01794434.

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BATES, JONATHAN J., and JOSÉ L. ZAYAS-CASTRO. "SELECTING THE BEST PERFORMING WEIBULL ESTIMATION METHOD FOR RANDOMLY RIGHT CENSORED DATA." International Journal of Reliability, Quality and Safety Engineering 17, no. 02 (2010): 105–18. http://dx.doi.org/10.1142/s021853931000369x.

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A total of nine methods are compared and tables are presented for selecting the best performing estimator for a two-parameter Weibull distribution using randomly right censored data. The results indicate that a best performing method can be selected given a certain sample size, censoring level, and shape parameter range. Such a comparison of estimators is necessary as the best performing method is shown to vary across these values. The estimation methods tested include the Maximum Likelihood Estimator, Kaplan-Meier Estimator, Piecewise Exponential Estimator, Földes, Rejt, and Winter Estimator,

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PATEL, MINNIE H., and H. S. JACOB TSAO. "FORWARD APPORTIONMENT OF CENSORED COUNTS FOR DISCRETE NONPARAMETRIC MAXIMUM LIKELIHOOD ESTIMATION OF FAILURE PROBABILITIES." International Journal of Reliability, Quality and Safety Engineering 16, no. 03 (2009): 213–34. http://dx.doi.org/10.1142/s0218539309003368.

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Empirical cumulative lifetime distribution function is often required for selecting lifetime distribution. When some test items are censored from testing before failure, this function needs to be estimated, often via the approach of discrete nonparametric maximum likelihood estimation (DN-MLE). In this approach, this empirical function is expressed as a discrete set of failure-probability estimates. Kaplan and Meier used this approach and obtained a product-limit estimate for the survivor function, in terms exclusively of the hazard probabilities, and the equivalent failure-probability estimat

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SAKAI, Yuki, Masato UCHIDA, Masato TSURU, and Yuji OIE. "Impact of Censoring on Estimation of Flow Duration Distribution and Its Mitigation Using Kaplan-Meier-Based Method." IEICE Transactions on Information and Systems E92-D, no. 10 (2009): 1949–52. http://dx.doi.org/10.1587/transinf.e92.d.1949.

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19

Boracchi, Patrizia, and Annalisa Orenti. "Survival Functions in the Presence of Several Events and Competing Risks: Estimation and Interpretation Beyond Kaplan- Meier." International Journal of Statistics in Medical Research 4, no. 1 (2015): 121–39. http://dx.doi.org/10.6000/1929-6029.2015.04.01.14.

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Ragab, Ahmed, Mohamed-Salah Ouali, Soumaya Yacout, and Hany Osman. "Remaining useful life prediction using prognostic methodology based on logical analysis of data and Kaplan–Meier estimation." Journal of Intelligent Manufacturing 27, no. 5 (2014): 943–58. http://dx.doi.org/10.1007/s10845-014-0926-3.

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21

Nemes, Szilárd, Erik Bülow, and Andreas Gustavsson. "A Brief Overview of Restricted Mean Survival Time Estimators and Associated Variances." Stats 3, no. 2 (2020): 107–19. http://dx.doi.org/10.3390/stats3020010.

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Restricted Mean Survival Time ( R M S T ) experiences a renaissance and is advocated as a model-free, easy to interpret alternative to proportional hazards regression and hazard rates with implication in causal inference. Estimation of R M S T and associated variance is mainly done by numerical integration of Kaplan–Meier curves. In this paper we briefly review the two main alternatives to the Kaplan–Meier method; analysis based on pseudo-observations, and the flexible parametric survival method. Using computer simulations, we assess the efficacy of the three methods compared to a fully parame

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Heupel, M. R., and C. A. Simpfendorfer. "Estimation of mortality of juvenile blacktip sharks, Carcharhinus limbatus, within a nursery area using telemetry data." Canadian Journal of Fisheries and Aquatic Sciences 59, no. 4 (2002): 624–32. http://dx.doi.org/10.1139/f02-036.

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A population of young blacktip sharks (Carcharhinus limbatus) was monitored over three years to determine their mortality rates using a series of acoustic listening stations. Based on these data it was possible to use several mortality estimators, including indirect life history based methods and direct methods such as the Kaplan-Meier and SURVIV methods, to estimate natural, fishing, and total mortality. Kaplan-Meier (6191%) and SURVIV (6292%) methods provided nearly identical total mortality rates during the first six months of life. This agreement suggests that these estimates are accurat

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Hansen, Martin B., Adrian J. Baddeley, and Richard D. Gill. "First contact distributions for spatial patterns: regularity and estimation." Advances in Applied Probability 31, no. 1 (1999): 15–33. http://dx.doi.org/10.1239/aap/1029954263.

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For applications in spatial statistics, an important property of a random set X in ℝk is its first contact distribution. This is the distribution of the distance from a fixed point 0 to the nearest point of X, where distance is measured using scalar dilations of a fixed test set B. We show that, if B is convex and contains a neighbourhood of 0, the first contact distribution function FB is absolutely continuous. We give two explicit representations of FB, and additional regularity conditions under which FB is continuously differentiable. A Kaplan-Meier estimator of FB is introduced and its bas

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Zhang, Fan, Hong Liu, Xiaoli Gong, et al. "Risk Factors for Mortality in Chinese Patients on Continuous Ambulatory Peritoneal Dialysis." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 35, no. 2 (2015): 199–205. http://dx.doi.org/10.3747/pdi.2013.00164.

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ObjectiveThe intent of this study was to evaluate the clinical outcome and risk factors affecting mortality of the continuous ambulatory peritoneal dialysis (CAPD) patients in a single peritoneal dialysis (PD) center over a period of 10 years.Patients and methodsWe retrospectively analyzed patients on PD from June 2001 to June 2011. The clinical and biochemical data were collected from the medical records. Clinical variables included gender, age at the start of PD, smoking status, body mass index (BMI), cause of end-stage renal disease (ESRD), presence of diabetes mellitus and blood pressure.

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Macdonald, A. S. "An Actuarial Survey of Statistical Models for Decrement and Transition Data, II. Competing Risks, Non-Parametric and Regression Models." British Actuarial Journal 2, no. 2 (1996): 429–48. http://dx.doi.org/10.1017/s1357321700003469.

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ABSTRACTThis paper surveys some statistical models of survival data. Competing risks models are described; the unidentifiability of net decrements suggests a sceptical approach to the use of underlying single decrement tables. Approaches based on observations of complete lifetimes (with censoring) are surveyed including the Kaplan-Meier and Nelson-Aalen estimates. Regression models for lifetimes depending on covariates are discussed, in particular the Cox model and partial likelihood estimation.

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Hansen, Martin B., Adrian J. Baddeley, and Richard D. Gill. "First contact distributions for spatial patterns: regularity and estimation." Advances in Applied Probability 31, no. 01 (1999): 15–33. http://dx.doi.org/10.1017/s0001867800008922.

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For applications in spatial statistics, an important property of a random set X in ℝ k is its first contact distribution. This is the distribution of the distance from a fixed point 0 to the nearest point of X, where distance is measured using scalar dilations of a fixed test set B. We show that, if B is convex and contains a neighbourhood of 0, the first contact distribution function F B is absolutely continuous. We give two explicit representations of F B , and additional regularity conditions under which F B is continuously differentiable. A Kaplan-Meier estimator of F B is introduced and i

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Lequeux, T., A. Badreldin, S. Saussez, M. P. Thill, L. Oujjan, and G. Chantrain. "A comparison of survival lifetime of the Provox® and the Provox®2 voice prosthesis." Journal of Laryngology & Otology 117, no. 11 (2003): 875–78. http://dx.doi.org/10.1258/002221503322542881.

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The Provox® (Atos Medical AB, Hörby, Sweden) voice prosthesis was developed between 1988 and 1990 and has been used at our centre with regular success since 1993. Since 1996, a second generation of Provox® (Provox®2) has been used, which can be inserted by an anterograde technique. The aim of this study is to compare the survival lifetime of both voice prostheses. The survival time of the two voice prostheses were compared retrospectively in 152 devices placed in 38 patients. A Kaplan-Meier analysis was performed to determine the survival lifetimes and a log rank test was performed to compare

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O'Sullivan, Matthew V. N., Vitali Sintchenko, and Gwendolyn L. Gilbert. "Quantitative Estimation of the Stability of Methicillin-Resistant Staphylococcus aureus Strain-Typing Systems by Use of Kaplan-Meier Survival Analysis." Journal of Clinical Microbiology 51, no. 1 (2012): 112–16. http://dx.doi.org/10.1128/jcm.01406-12.

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Adamu, Patience I., Muminu O. Adamu, Hilary I. Okagbue, Laban Opoola, and Sheila A. Bishop. "Survival Analysis of Cancer Patients in North Eastern Nigeria from 2004 – 2017 – A Kaplan - Meier Method." Open Access Macedonian Journal of Medical Sciences 7, no. 4 (2019): 642–49. http://dx.doi.org/10.3889/oamjms.2019.109.

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BACKGROUND: Cancer is a deadly malignant disease and is prevalent in Sub Saharan Africa. The North East part of Nigeria in particular and the country, in general, are struggling to cope with the increasing burden of cancer and other communicable and non-communicable diseases. The situation is worsened by the ongoing insurgency and terrorist activities in the area. AIM: The aim of this paper is to present the research findings from a cohort study aimed at the analysis of the estimation of the survivorship time of the real data of cancer patients in the North-eastern part of Nigeria and to

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Brooks, Jordan C., Mark J. van der Laan, Daniel E. Singer, and Alan S. Go. "Targeted Minimum Loss-Based Estimation of Causal Effects in Right-Censored Survival Data with Time-Dependent Covariates: Warfarin, Stroke, and Death in Atrial Fibrillation." Journal of Causal Inference 1, no. 2 (2013): 235–54. http://dx.doi.org/10.1515/jci-2013-0001.

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AbstractCausal effects in right-censored survival data can be formally defined as the difference in the marginal cumulative event probabilities under particular interventions. Conventional estimators, such as the Kaplan-Meier (KM), fail to consistently estimate these marginal parameters under dependent treatment assignment or dependent censoring. Several modern estimators have been developed that reduce bias under both dependent treatment assignment and dependent censoring by incorporating information from baseline and time-dependent covariates. In the present article we describe a recently de

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Abecassis, Wainstock, Sheiner, and Pariente. "Perinatal Outcome and Long-Term Gastrointestinal Morbidity of Offspring of Women with Celiac Disease." Journal of Clinical Medicine 8, no. 11 (2019): 1924. http://dx.doi.org/10.3390/jcm8111924.

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The aim of this study was to evaluate perinatal outcome and long-term offspring gastrointestinal morbidity of women with celiac disease. Perinatal outcomes, as well as long-term gastrointestinal morbidity of offspring of mothers with and without celiac disease were assessed. The study groups were followed until 18 years of age for gastrointestinal-related morbidity. For perinatal outcomes, generalized estimation equation (GEE) models were used. A Kaplan–Meier survival curve was used to compare cumulative incidence of long-term gastrointestinal morbidity, and Cox proportional hazards models wer

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Hoogendoorn, Serge P. "Vehicle-Type and Lane–Specific Free Speed Distributions on Motorways." Transportation Research Record: Journal of the Transportation Research Board 1934, no. 1 (2005): 148–56. http://dx.doi.org/10.1177/0361198105193400116.

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A new approach to estimation of vehicle type–specific free speed distributions on multilane facilities is presented on the basis of the concept of censored observations. The original distribution-free method of Kaplan and Meier is generalized to include partially censored data, i.e., observations that are censored with a certain probability or to a certain degree. The method is applied with cross-section data collected at a busy two-lane motorway in the Netherlands. The results provide robust estimates of the speed distributions for different vehicle classes, while they remove the structural e

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Merkle, Julia, Anton Sabashnikov, Lisa Liebig, et al. "Factors predictive for early and late mortality after surgical repair for Stanford A acute aortic dissection." Perfusion 34, no. 5 (2019): 375–83. http://dx.doi.org/10.1177/0267659118822947.

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Objectives: The aim of this study was to evaluate independent risk factors predictive for mortality of patients with Stanford A acute aortic dissection. Methods: From January 2006 to March 2015, a total of 240 consecutive patients diagnosed with acute Stanford A acute aortic dissection underwent surgical aortic repair in our center. After analysis of pre- and perioperative variables, univariate logistic and multivariate logistic regression analyses were performed for mortality of patients. Subsequently, Kaplan–Meier estimation analysis of short- and long-term survival of these variables was ca

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Shabto, Julie M., Dylan J. Martini, Yuan Liu, et al. "Sites of metastases (mets) and their association with clinical outcomes (CO) in urothelial cancer patients (pts) treated with immunotherapy (IO)." Journal of Clinical Oncology 37, no. 7_suppl (2019): 473. http://dx.doi.org/10.1200/jco.2019.37.7_suppl.473.

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473 Background: Several IO agents have been approved for treatment of advanced urothelial cancer pts. We investigated the association between sites of mets and CO in urothelial cancer pts treated with IO in the real world setting. Methods: We performed a retrospective review of 67 urothelial cancer pts treated with PD-1 or PD-L1 inhibitors at Winship Cancer Institute from 2015-2018. Overall survival (OS) and progression free survival (PFS) were measured from first dose of IO to date of death or hospice referral and radiographic or clinical progression, respectively. Sites of mets were collecte

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Alhissan, Abdurahman S., and Sharat Chandra Pani. "Factors Influencing the Survival of Preformed Zirconia Crowns in Children Treated under General Anesthesia." International Journal of Dentistry 2021 (March 17, 2021): 1–5. http://dx.doi.org/10.1155/2021/5515383.

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Aim. This study aimed to retrospectively evaluate the success of zirconia crowns placed in the anterior teeth of children and evaluate the impact of pulp therapy of the tooth on the rate of failure. Materials and Methods. A total of 70 anterior teeth of 20 children aged between 3 and 5 years who had undergone the placement of zirconia crowns under general anesthesia were followed up for 24 months. Kaplan–Meier Survival curves were plotted for the estimation of two-year survival time. The outcomes for teeth that had received pulp therapy were compared to those that had not received pulp therapy

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Jonker, Marianne A., Johannes A. Rijken, Frederik J. Hes, Hein Putter, and Erik F. Hensen. "Estimating the penetrance of pathogenic gene variants in families with missing pedigree information." Statistical Methods in Medical Research 28, no. 10-11 (2018): 2924–36. http://dx.doi.org/10.1177/0962280218791338.

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Accurate assessment of the age-dependent disease risk conferred by germline variants in disease susceptibility genes is often hampered by the way the data are collected. Cohort-based data sets frequently contain an overrepresentation of patients (i.e. carriers of the gene variant of interest affected with the associated disease), and an underrepresentation of disease-free carriers. In order to overcome this problem, penetrance estimates can be based on family-based study designs, through the evaluation of index patients and their family members. This approach facilitates the identification of

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Putter, Hein, and Cristian Spitoni. "Non-parametric estimation of transition probabilities in non-Markov multi-state models: The landmark Aalen–Johansen estimator." Statistical Methods in Medical Research 27, no. 7 (2016): 2081–92. http://dx.doi.org/10.1177/0962280216674497.

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The topic non-parametric estimation of transition probabilities in non-Markov multi-state models has seen a remarkable surge of activity recently. Two recent papers have used the idea of subsampling in this context. The first paper, by de Uña Álvarez and Meira-Machado, uses a procedure based on (differences between) Kaplan–Meier estimators derived from a subset of the data consisting of all subjects observed to be in the given state at the given time. The second, by Titman, derived estimators of transition probabilities that are consistent in general non-Markov multi-state models. Here, we sho

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Sipahioglu, Murat Hayri, Aysun Aybal, Aydin Ünal, Bulent Tokgoz, Oktay Oymak, and Cengiz Utaş. "Patient and Technique Survival and Factors Affecting Mortality on Peritoneal Dialysis in Turkey: 12 Years’ Experience in a Single Center." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 28, no. 3 (2008): 238–45. http://dx.doi.org/10.1177/089686080802800309.

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Background We investigated patient and technique survival and factors affecting mortality in Turkish peritoneal dialysis (PD) patients. Patients and Methods This was a retrospective study. 423 PD patients were included. The demographic, clinical, and biochemical data were collected from the medical records. Clinical outcomes were mortality and technique failure. Results Mean age at the start of PD was 46.0 ± 14.3 years and mean PD duration was 37.1 ± 28.3 (median: 30, range: 4 – 137) months. Diabetes mellitus was the most common cause of end-stage renal disease (35.2%), followed by hypertensio

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Rebora, Paola, and Maria Grazia Valsecchi. "Survival estimation in two-phase cohort studies with application to biomarkers evaluation." Statistical Methods in Medical Research 25, no. 6 (2016): 2895–908. http://dx.doi.org/10.1177/0962280214534411.

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Two-phase studies are attractive for their economy and efficiency in research settings where large cohorts are available for investigating the prognostic and predictive role of novel genetic and biological factors. In this type of study, information on novel factors is collected only in a convenient subcohort (phase II) drawn from the cohort (phase I) according to a given (optimal) sampling strategy. Estimation of survival in the subcohort needs to account for the design. The Kaplan–Meier method, based on counts of events and of subjects at risk in time, must be applied accounting, with suitab

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Pak, Kyongsun, Yu Sunakawa, Masahiro Takeuchi, Wataru Ichikawa, and Masashi Fujii. "The parametric estimation procedure to predict long-term efficacy on survival from publication data of clinical trials for metastatic colorectal cancer (mCRC)." Journal of Clinical Oncology 37, no. 4_suppl (2019): 541. http://dx.doi.org/10.1200/jco.2019.37.4_suppl.541.

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541 Background: In comparative clinical trials with time-to-event outcomes, the long-term treatment effect profile is clinically crucial. The conventional non-parametric measures, i.e., the median survival times and the t-year survival rates are informative but sometimes cannot be observed due to the limited study follow-up. For example, in the PEAK trial (Schwartzberg LS et al. J Clin Oncol 2014), the group contrast over 3 years could not be adequately confirmed due to the short follow-up. To predict the subsequent survival prognosis with the limited outcome data, one may estimate the surviva

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Liu, XiuLan, Guangji Yang, Juan Huang, et al. "KRAS SNPs are related to colorectal cancer susceptibility and survival in Chinese people." Biomarkers in Medicine 14, no. 1 (2020): 13–22. http://dx.doi.org/10.2217/bmm-2019-0172.

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Aim: KRAS SNPs may increase KRAS transcription and KRAS levels. SNPs of KRAS 3′UTR can affect carcinoma risk and prognosis. Materials & methods: The rs8720 and rs7960917 in KRAS 3′UTR for colorectal carcinoma (CRC) risk and survival were investigated in a case–control study. Association between SNPs and CRC risk, survival analysis were analyzed by an unconditional logistic regression model, log-rank test, Kaplan–Meier estimation, Cox regression model and one-way analysis of variance. Results & conclusion: The genotype CT of rs8720 was significantly increased risk of CRC, decreased over

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Utaş, Cengiz. "Patient and Technique Survival on Capd in Turkey." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 21, no. 6 (2001): 602–6. http://dx.doi.org/10.1177/089686080102100611.

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Objective To analyze the status of continuous ambulatory peritoneal dialysis (CAPD) in 12 centers in Turkey. Design Retrospective study of CAPD technique and patient outcome. Setting University hospital renal units. Patients 334 patients [205 males (61%), 129 (39%) females; mean age 42.2 ± 13.8 years; mean follow-up time 23.5 ± 18.3 months] beginning CAPD between March 1992 and December 1999, and having a minimum follow-up of 3 months. Outcome Measure Patient survival, technique survival, and duration of hospitalization. Results Mean weekly Kt/V urea was 1.9 ± 0.8, weekly creatinine clearance

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Martin-Rodriguez, E., F. Guillen-Grima, E. Aubá, A. Martí, and A. Brugos-Larumbe. "Relationship between body mass index and depression in women: A 7-year prospective cohort study. The APNA study." European Psychiatry 32 (February 2016): 55–60. http://dx.doi.org/10.1016/j.eurpsy.2015.11.003.

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AbstractBackgroundThe association between body mass index (BMI) and depression is complex and controversial. The present study examined the relationship between BMI and new-onset depression during 7 years of follow-up in 20,212 adult women attending Primary Health Care Centres in Navarra, Spain.MethodsThe Atención Primaria de Navarra (APNA) study is a dynamic prospective cohort study. A total of 20,212 women aged 18–99 years (mean age: 50.7 ± 18.5 years) without depression at baseline were selected from 2004 to 2011. We estimated the incidence of depression. We used the Kaplan-Meier analysis t

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Oudard, S., F. Joulain, A. De Geer, and A. O. Sartor. "Cabazitaxel or mitoxantrone with prednisone in patients with metastatic castration-resistant prostate cancer (mCRPC) previously treated with docetaxel: Estimating mean overall survival (OS) for health economic analyses from a phase III trial (TROPIC)." Journal of Clinical Oncology 29, no. 7_suppl (2011): 128. http://dx.doi.org/10.1200/jco.2011.29.7_suppl.128.

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128^ Background: TROPIC evaluated the efficacy and safety of the novel taxane cabazitaxel in men with mCRPC previously treated with docetaxel. Median OS was significantly improved, as previously reported (12.7 months in mitoxantrone arm vs 15.1 months in cabazitaxel arm, HR=0.72 [0.61 – 0.84], p<0.0001- updated OS results). Median OS is the most useful descriptive statistic for physicians and patients as it reflects a point estimate in time by which 50% patients may survive regardless of disease status or progression. It avoids assumptions on long-term survival beyond the follow-up period o

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Vos, Janet R., Li Hsu, Richard M. Brohet, et al. "Bias Correction Methods Explain Much of the Variation Seen in Breast Cancer Risks of BRCA1/2 Mutation Carriers." Journal of Clinical Oncology 33, no. 23 (2015): 2553–62. http://dx.doi.org/10.1200/jco.2014.59.0463.

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Purpose Recommendations for treating patients who carry a BRCA1/2 gene are mainly based on cumulative lifetime risks (CLTRs) of breast cancer determined from retrospective cohorts. These risks vary widely (27% to 88%), and it is important to understand why. We analyzed the effects of methods of risk estimation and bias correction and of population factors on CLTRs in this retrospective clinical cohort of BRCA1/2 carriers. Patients and Methods The following methods to estimate the breast cancer risk of BRCA1/2 carriers were identified from the literature: Kaplan-Meier, frailty, and modified seg

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Nunez, Robert A., Stephen P. Cass, Joseph M. Furman, and G. Richard Holt. "Short- and Long-Term Outcomes of Canalith Repositioning for Benign Paroxysmal Positional Vertigo." Otolaryngology–Head and Neck Surgery 122, no. 5 (2000): 647–53. http://dx.doi.org/10.1016/s0194-5998(00)70190-2.

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This is a prospective, nonrandomized study of the canalith repositioning procedure (CRP) for treatment of benign paroxysmal positional vertigo (BPPV). CRP was used to treat 168 patients with BPPV. Patient data were gathered by yearly telephone interviews to determine whether symptoms of position-induced vertigo had returned. After 1 or 2 treatment sessions 91.3% of patients reported complete symptom resolution. Average follow-up for the study population after the initial treatment was 26 months. A recurrence rate of 26.8% was found among those patients who initially reported resolution of symp

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Nunez, Robert A., Stephen P. Cass, and Joseph M. Furman. "Short- and long-term outcomes of canalith repositioning for benign paroxysmal positional vertigo." Otolaryngology–Head and Neck Surgery 122, no. 5 (2000): 647–52. http://dx.doi.org/10.1067/mhn.2000.105185.

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This is a prospective, nonrandomized study of the canalith repositioning procedure (CRP) for treatment of benign paroxysmal positional vertigo (BPPV). CRP was used to treat 168 patients with BPPV. Patient data were gathered by yearly telephone interviews to determine whether symptoms of position-induced vertigo had returned. After 1 or 2 treatment sessions 91.3% of patients reported complete symptom resolution. Average follow-up for the study population after the initial treatment was 26 months. A recurrence rate of 26.8% was found among those patients who initially reported resolution of symp

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Yılmaz, Ersin, Syed Ejaz Ahmed, and Dursun Aydın. "A-Spline Regression for Fitting a Nonparametric Regression Function with Censored Data." Stats 3, no. 2 (2020): 120–36. http://dx.doi.org/10.3390/stats3020011.

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This paper aims to solve the problem of fitting a nonparametric regression function with right-censored data. In general, issues of censorship in the response variable are solved by synthetic data transformation based on the Kaplan–Meier estimator in the literature. In the context of synthetic data, there have been different studies on the estimation of right-censored nonparametric regression models based on smoothing splines, regression splines, kernel smoothing, local polynomials, and so on. It should be emphasized that synthetic data transformation manipulates the observations because it as

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Zhang, Enfan, Xi Huang, and Jingsong He. "Integrated bioinformatic analysis of HNF1A in human cancers." Journal of International Medical Research 49, no. 3 (2021): 030006052199732. http://dx.doi.org/10.1177/0300060521997326.

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ObjectivesCancer is a threat to human health, and many molecules are involved in the transformation of malignant cells. Hepatocyte nuclear factor 1A (HNF1A) is an important transcription factor that regulates multiple biological processes. Our research focused on elucidating the expression and function of HNF1A in cancer through bioinformatic analysis.MethodsUALCAN, Kaplan–Meier plotter, COSMIC, Tumor IMmune Estimation Resource, and Cancer Regulome were used to obtain relevant data for HNF1A.ResultsHNF1A was abnormally expressed in multiple cancers, and its expression was associated with diffe

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Tuli, Sagun K., Jayshree Tuli, Peng Chen, and Eric J. Woodard. "Fusion rate: a time-to-event phenomenon." Journal of Neurosurgery: Spine 1, no. 1 (2004): 47–51. http://dx.doi.org/10.3171/spi.2004.1.1.0047.

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Object. The term “fusion rate” is generally denoted in the literature as the percentage of patients with successful fusion over a specific range of follow up. Because the time to fusion is a time-to-event phenomenon a more accurate method of representation may be made using the Kaplan—Meier method of estimation. Methods. The current study was performed to illustrate that fusion rate is more accurately represented by median times as calculated using survival analysis. Patients undergoing a cervical decompressive corpectomy and reconstruction formed the basis of the primary analysis. A secondary

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