Academic literature on the topic 'Etoposide Solubility'

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Journal articles on the topic "Etoposide Solubility"

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Zhang, Li-Song, Li-Xin Yan, Shan Gao, et al. "Self-assembling peptide–etoposide nanofibers for overcoming multidrug resistance." Chemical Communications 56, no. 97 (2020): 15321–24. http://dx.doi.org/10.1039/d0cc06387h.

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Nap-GFFpYK-etoposide1/2 (NFE1/2) increase the water solubility of etoposide, speed up its cellular uptake and protect the etoposide from MDR-mediated efflux, thus significantly improving the anticancer efficacy.
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Zhang, Fang, Gar Yee Koh, Javoris Hollingsworth, Paul S. Russo, Rhett W. Stout, and Zhijun Liu. "Reformulation of etoposide with solubility-enhancing rubusoside." International Journal of Pharmaceutics 434, no. 1-2 (2012): 453–59. http://dx.doi.org/10.1016/j.ijpharm.2012.06.013.

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Du, J., and R. C. Vasavada. "Solubility and Dissolution of Etoposide from Solid Dispersions of PEG 8000." Drug Development and Industrial Pharmacy 19, no. 8 (1993): 903–14. http://dx.doi.org/10.3109/03639049309062990.

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Beig, Avital, Jonathan M. Miller, David Lindley, et al. "Head-To-Head Comparison of Different Solubility-Enabling Formulations of Etoposide and Their Consequent Solubility–Permeability Interplay." Journal of Pharmaceutical Sciences 104, no. 9 (2015): 2941–47. http://dx.doi.org/10.1002/jps.24496.

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Varshosaz, Jaleh, Farshid Hasanzadeh, and Mojtaba Eslamdoost. "Optimization of self-assembling properties of fatty acids grafted to methoxy poly(ethylene glycol) as nanocarriers for etoposide." Acta Pharmaceutica 62, no. 1 (2012): 31–44. http://dx.doi.org/10.2478/v10007-012-0006-1.

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Optimization of self-assembling properties of fatty acids grafted to methoxy poly(ethylene glycol) as nanocarriers for etoposide The objective of this work was to study the effect of fatty acid chain length grafted to methoxy poly(ethylene glycol) (mPEG) on self assembling properties of micelles for etoposide delivery. Three amphiphilic copolymers were synthesized using mPEG, myristic acid, stearic acid and behenic acid through an esteric linkage. The particle size and zeta potential of the micelles were determined by the dynamic light scattering method. Etoposide was loaded into micelles by f
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Darwish, I. A., A. T. Florence, and A. M. Saleh. "Effects of Hydrotropic Agents on the Solubility, Precipitation, and Protein Binding of Etoposide." Journal of Pharmaceutical Sciences 78, no. 7 (1989): 577–81. http://dx.doi.org/10.1002/jps.2600780714.

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Shah, Jaymin C., Jivn R. Chen, and Diana Chow. "Preformulation study of etoposide: II. Increased solubility and dissolution rate by solid-solid dispersions." International Journal of Pharmaceutics 113, no. 1 (1995): 103–11. http://dx.doi.org/10.1016/0378-5173(94)00195-b.

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Alfei, Silvana, Barbara Marengo, and Cinzia Domenicotti. "Polyester-Based Dendrimer Nanoparticles Combined with Etoposide Have an Improved Cytotoxic and Pro-Oxidant Effect on Human Neuroblastoma Cells." Antioxidants 9, no. 1 (2020): 50. http://dx.doi.org/10.3390/antiox9010050.

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Etoposide (ETO) is a cytotoxic drug that exerts its effect by increasing reactive oxygen species (ROS) production. Although ETO is widely used, fast metabolism, poor solubility, systemic toxicity, and multi-drug resistance induction all limit its administration dosage and its therapeutic efficiency. In order to address these issues, a biodegradable dendrimer was prepared for entrapping and protecting ETO and for enhancing its solubility and effectiveness. The achieved dendrimer complex with ETO (CPX 5) showed the typical properties of a well-functioning delivery system, i.e., nanospherical mor
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Soćko, Renata. "Etoposide. Documentation of proposed values of occupational exposure limits (OELs)." Podstawy i Metody Oceny Środowiska Pracy 36, no. 2(100) (2019): 73–98. http://dx.doi.org/10.5604/01.3001.0013.2532.

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Etoposide at room temperature is a solid present in the form of a white or yellow-brown crystalline powder. It is an anticancer drug with cytotoxic and anti-mitotic activity, used to treat patients with testicular cancer, acute myelogenous leukemia, lung cancer, non-small-cell lung cancer, adrenal cortex cancer, gastric cancer, hepatoblastoma, acute lymphoblastic leukemia and brain tumors. It is also recommended for the treatment of Ewing sarcoma and Kaposi's sarcoma associated with AIDS. This cytostatic is available in capsules taken by food and in concentrate for solution for infusion. Occup
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Beig, Avital, Noa Fine-Shamir, Daniel Porat, David Lindley, Jonathan M. Miller, and Arik Dahan. "Concomitant solubility-permeability increase: Vitamin E TPGS vs. amorphous solid dispersion as oral delivery systems for etoposide." European Journal of Pharmaceutics and Biopharmaceutics 121 (December 2017): 97–103. http://dx.doi.org/10.1016/j.ejpb.2017.09.012.

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Dissertations / Theses on the topic "Etoposide Solubility"

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Kashyap, Lola. "Studies on the effect of palmitylcarnitine chloride on the solubility of etoposide : thesis." Scholarly Commons, 1988. https://scholarlycommons.pacific.edu/uop_etds/2169.

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Tu, Chieh. "Solubility and dissolution behavior of etoposide from solid dispersion of xylitol or PEG 8000 ; a thesis." Scholarly Commons, 1990. https://scholarlycommons.pacific.edu/uop_etds/2204.

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Du, Jie. "Solubility and dissolution behavior of etoposide from solid dispersion of Xylitol or PEG 8000." Scholarly Commons, 1990. https://scholarlycommons.pacific.edu/uop_etds/3105.

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The solid glass dispersions of xylitol or PEG 8000 containing etoposide were prepared by the fusion method. The preliminary studies established that the etoposide was stable in water for three days at 37• ±. 0. s•c either from solid glass dispersion or physical mixture with xylitol or PEG 8000, with no significant change in pH. Thin layer chromatography and infra red spectroscopy of the samples suggested that the drug and the carrier (xylitol or PEG 8000) were stable and did not decompose during the fusion process. The solubility of etoposide from solid glass dispersion with etoposide:xylitol
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