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Relevant bibliographies by topics / Eudragit S100 and Span 80

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Journal articles

Academic literature on the topic 'Eudragit S100 and Span 80'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Eudragit S100 and Span 80"

1

Diksha, Saitwal *. Dr Surajj Sarode Dr. S.D. Barhate. "FORMULATION AND EVALUATION OF COLON TARGETED SULFASALAZINE MICROSPHERES." Journal of Scientific Research in Pharmacy 8, no. 7 (2019): 75–84. https://doi.org/10.5281/zenodo.3370363.

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<strong><em>ABSTRACT</em></strong> <strong><em>S</em></strong><em>ulfasalazine is an anti-inflammatory drug used in the treatment of ulcerative colitis. It is metabolised in colon by the bacterial enzyme azoreductase to sulfapyridine and 5-amino salicylic acid. It is rapidly absorbed in the intestine, hence it is necessary to develop colon targeted drug delivery system. Sulfasalazine releases 5-ASA which decreases the inflammation of intestine & thus helpful in ulcerative colitis. The main objective of the present research is formulated and evaluated colon targeted sulfasalazine microspher

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2

Rajesh, Katta, R. Deveswaran, S. Bharath, and B. V. Basavaraj. "DEVELOPMENT OF MESALAZINE MICROSPHERES FOR COLON TARGETING." International Journal of Applied Pharmaceutics 9, no. 4 (2017): 1. http://dx.doi.org/10.22159/ijap.2017v9i4.17326.

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Objective: The present work was aimed at preparation of mesalazine microspheres by a non-aqueous solvent evaporation method using eudragit S 100 and eudragit L 100 as pH dependent polymers for colon targeting.Methods: The ratio of drug to polymer was varied and the effect of formulation variables revolutions per minute (RPM) (1000, 1500, 2000 and 2500) and concentration of span 80 (1%, 1.5%, 2% and 2.5%) were studied. Prepared microspheres were evaluated for particle size, percent drug entrapment, granular analysis, in vitro drug release studies, Fourier transformed infrared spectroscopy (FT-I

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3

Tanwar, Yuveraj, Chetan Chauhan, and Anshu Sharma. "Development and evaluation of carvedilol transdermal patches." Acta Pharmaceutica 57, no. 2 (2007): 151–59. http://dx.doi.org/10.2478/v10007-007-0012-x.

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Development and evaluation of carvedilol transdermal patchesTransdermal patches of carvedilol with a HPMC-drug reservoir were prepared by the solvent evaporation technique. In this investigation, the membranes of Eudragit RL100 and Eudragit RS100 were cast to achieve controlled release of the drug. The prepared patches possessed satisfactory physicochemical characteristics. Thickness, mass and drug content were uniform in prepared batches. Moisture vapour transmission through the patches followed zero-order kinetics.In vitropermeation studies were performed using a K-C diffusion cell across ha

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Pandav, Satish, and Jitendra Naik. "Preparation and In Vitro Evaluation of Ethylcellulose and Polymethacrylate Resins Loaded Microparticles Containing Hydrophilic Drug." Journal of Pharmaceutics 2014 (April 10, 2014): 1–5. http://dx.doi.org/10.1155/2014/904036.

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Objective. The purpose of the recent study was to prepare and estimate sustained release of Ethylcellulose (300 cps) and Eudragit (RS 100 and RL 100) microparticles containing Propranolol hydrochloride used as a treatment of cardiovascular system, especially hypertension. Method. Propranolol hydrochloride was microencapsulated with different polymers (Ethylcellulose, Eudragit RS, and Eudragit RL) using modified hydrophobic (O/O) solvent evaporation method using 1 : 1 combination of acetone and isopropanol as the internal phase. Obtained microparticles were showing higher batch yield with highe

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5

Atmakuri, Lakshmana Rao, Jhansi Nelapati, Bhaskar Vallamkonda, Ranadheer Reddy Challa, Subrahmanya Sai Malleswara Sharma Sonti, and Krishna Sudarsana Bhuvanagiri. "Design and Development of Saxagliptin Microparticles for Diabetes." Biomedical and Pharmacology Journal 17, no. 4 (2024): 2287–94. https://doi.org/10.13005/bpj/3024.

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This study investigates the design, development, and evaluation of sustained-release Saxagliptin microparticles, utilizing Eudragit L-100 and Eudragit S-100 as polymers to achieve prolonged drug release. A total of eight formulations were prepared, employing varying drug-to-polymer ratios (1:1, 1:2, 1:3, and 1:4) for both core and coat materials. This approach facilitated an assessment of the concentration of coating material influenced the drug release rate. The solvent evaporation method proved effective in producing discrete, spherical microparticles characterized by good flowability and mi

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6

Srilatha, Ch, and T. Giriraj kulkarni. "Formulation and Evaluation of Colon Targeted Ciprofloxacin Microspheres." Trends in Pharmaceuticals and Nanotechnology 5, no. 2 (2023): 31–40. http://dx.doi.org/10.46610/tpnt.2023.v05i02.004.

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In the present study, Colon-targeted Ciprofloxacin hydrochloride microspheres were formulated and their in vitro properties were assessed to determine whether or not the antibiotic could be delivered to the colon. By utilizing span-80 as an emulsifying agent, ciprofloxacin hydrochloride microspheres for colon targeting were prepared using the emulsion-solvent evaporation method. According to the preliminary trial findings, the ratio of drug to polymer had an impact on the microspheres' properties. The Ciprofloxacin: Eudragit S-100+HPMC 6cps ratio of 1:1, 1:2, 1:3, 1:4, 1:5, and 1:6 were used t

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7

Chen, Ruiqi, Ruidong Zhai, Chao Wang, et al. "Compound Capecitabine Colon-Targeted Microparticle Prepared by Coaxial Electrospray for Treatment of Colon Tumors." Molecules 27, no. 17 (2022): 5690. http://dx.doi.org/10.3390/molecules27175690.

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To improve the antitumor effect of combined capecitabine (CAP) and osimertinib (OSI) therapy and quickly and efficiently reduce tumor volumes for preoperative chemotherapy, we designed a compound CAP colon-targeted microparticle (COPMP) prepared by coaxial electrospray. COPMP is a core–shell microparticle composed of a Eudragit S100 outer layer and a CAP/OSI-loaded PLGA core. In this study, we characterized its size distribution, drug loading (DL), encapsulation efficiency (EE), differential scanning calorimetry (DSC), Fourier transform infrared spectra (FTIR), in vitro release, formula ratio,

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8

Varia, Umang, Mohanlal Gupta, Hitesh Katariya, and Krunal Hakim. "Febuxostat Loaded Microballoons: A Novel Approach for Gastric Retention." International Journal of Pharmaceutical Sciences and Drug Research 13, no. 04 (2020): 438–47. http://dx.doi.org/10.25004/ijpsdr.2021.130410.

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Febuxostat loaded microballoons (FEB-MBs) were formulated using a non-aqueous solvent evaporation method using Eudragit RS 100, HPMC K4 M as a polymer, and span 80 as a surfactant. The ratio of solvents like methanol and dichloromethane, liquid paraffin as a processing medium. The formulation was optimized by the Box-Behnken design. Optimized formulation was evaluated for particle size, entrapment efficiency, % buoyancy, Percentage yield, in-vitro release studies, and stability study. Mean particle size 80.11 ± 0.349, entrapment efficient 83.25 ± 0.526, and % buoyancy 92.41 ± 0.57 were found f

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9

Rasheed, Qaiser, Kamran Ahmad Khan, Ghulam Razaque, et al. "Fabrication of glipizide loaded polymeric microparticles; in-vitro and in-vivo evaluation." PLOS ONE 20, no. 1 (2025): e0313523. https://doi.org/10.1371/journal.pone.0313523.

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Controlled-release microparticles offer a promising avenue for enhancing patient compliance and minimizing dosage frequency. In this study, we aimed to design controlled-release microparticles of Glipizide utilizing Eudragit S100 and Methocel K 100 M polymers as controlling agents. The microparticles were fabricated through a simple solvent evaporation method, employing various drug-to-polymer ratios to formulate different controlled-release batches labeled as F1 to F5. Evaluation of the microparticles encompassed a range of parameters including flow properties, particle size, morphology, perc

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10

Imran Ullah, Dr. Rahman Gul, Syed Umer Jan, et al. "Design, Formulation Development and Characterization of Transdermal Patches Loaded with Pseudoephedrine and Loratadine." Physical Education, Health and Social Sciences 3, no. 2 (2025): 822–30. https://doi.org/10.63163/jpehss.v3i2.422.

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ABSTARCT Objective The purpose of this study was to develop the transdermal patch with a combination of pseudoephedrine HCL and Loratadine . Methodology Various formulations of these anti-anthetic drugs were prepared using Eudragit RL100 as primary polymer. Ethyl cellulose (EC), twin 80, isopropyl myristate (IPM), Propylene Glycol (PG), and Span 20 were included as those who enhance transit. The finished patch was evaluated to their visual properties, including clarity, smoothness and brittleness. Additionally, thickness, pharmaceutical content, Fourier transform infrared spectroscopy (FTIR),

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