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Journal articles on the topic 'EVALUATION OF RESULTS OF THERAPEUTIC INTERVENTIONS/methods'

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Published: 4 June 2021

Last updated: 1 February 2022

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1

Makarewicz, Agata, Hanna Karakuła-Juchnowicz, and Łukasz Łobejko. "Review paper. Neuropsychological dimension of schizophrenia - evaluation possibilities and therapeutic implications." Current Problems of Psychiatry 18, no. 1 (2017): 51–61. http://dx.doi.org/10.1515/cpp-2017-0005.

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Abstract Introduction: In the last decades, researchers' attention has been focused on cognitive dysfunction in schizophrenia. Numerous studies indicate the existence of neurodegenerative deficits in schizophrenia including, but not limited to, motor functions, learning and memory, executive functions, attention, language, spatial skills and general intelligence. Method: A review of available literature on the topic of the past two decades, available in the Pubmed, EBSCO, SCOPUS databases has been made using the keywords: schizophrenia, cognition, early intervention. Results: Cognitive dysfunc

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Falco, Frank J. E. "An Update of Evaluation of Therapeutic Thoracic Facet Joint Interventions." Pain Physician 4;15, no. 4;8 (2012): E463—E481. http://dx.doi.org/10.36076/ppj.2012/15/e463.

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Background: Chronic mid back and upper back pain caused by thoracic facet joints has been reported in 34% to 48% of patients based on responses to controlled diagnostic blocks. Systematic reviews have established moderate evidence for controlled comparative local anesthetic blocks of thoracic facet joints in the diagnosis of mid back and upper back pain, moderate evidence for therapeutic thoracic medial branch blocks, and limited evidence for radiofrequency neurotomy of thoracic medial branches. Study Design: Systematic review of therapeutic thoracic facet joint interventions. Objective: To de

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Hansen, Hans. "A Systematic Evaluation of the Therapeutic Effectiveness of Sacroiliac Joint Interventions." Pain Physician 3;15, no. 3;5 (2012): E247—E278. http://dx.doi.org/10.36076/ppj.2012/15/e247.

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Background: The contribution of the sacroiliac joint to low back and lower extremity pain has been a subject of debate with extensive research. It is generally accepted that approximately 10% to 25% of patients with persistent low back pain may have pain arising from the sacroiliac joints. In spite of this, there are currently no definite conservative, interventional, or surgical management options for managing sacroiliac joint pain. In addition, there continue to be significant variations in the application of various techniques as well as a paucity of literature. Study Design: A systematic r

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Etemad, Koorosh, Zaher Khazaei, Sajjad Rahimi Pordanjani, et al. "Evaluation of the therapeutic interventions effects on body growth pattern of infants with congenital hypothyroidism." Biomedical Research and Therapy 5, no. 4 (2018): 2194–207. http://dx.doi.org/10.15419/bmrat.v5i4.433.

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Background: The congenital hypothyroidism (CH) is one of the most common congenital endocrine disorders as well as the most preventable mental retardation cause and body growth disorder. Several factors such as therapeutic interventions might affect the infants’ growth status. The current study was aimed to evaluate the therapeutic interventions’ effect on growth pattern of infants with congenital hypothyroidism in Yazd. Methods: This retrospective cohort study was performed on all neonates with CH, who were born during years 2006 and 2008. The effectiveness of therapeutic interventions

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Manchikanti, Laxmaiah. "Comprehensive Review of Therapeutic Interventions in Managing Chronic Spinal Pain." Pain Physician 4;12, no. 4;7 (2009): E123—E198. http://dx.doi.org/10.36076/ppj.2009/12/e123.

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Background: Available evidence documents a wide degree of variance in the definition and practice of interventional pain management. Objective: To provide evidence-based clinical practice guidelines for interventional techniques in the treatment of chronic spinal pain. Design: Best evidence synthesis. Methods: Strength of evidence was assessed by the U.S. Preventive Services Task Force (USPSTF) criteria utilizing 5 levels of evidence ranging from Level I to III with 3 subcategories in Level II. Outcomes: Short-term pain relief was defined as relief lasting 6 months or less and long-term relief

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Tremain, Hailey, Carla McEnery, Kathryn Fletcher, and Greg Murray. "The Therapeutic Alliance in Digital Mental Health Interventions for Serious Mental Illnesses: Narrative Review." JMIR Mental Health 7, no. 8 (2020): e17204. http://dx.doi.org/10.2196/17204.

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Background Digital mental health interventions offer unique advantages, and research indicates that these interventions are effective for a range of mental health concerns. Although these interventions are less established for individuals with serious mental illnesses, they demonstrate significant promise. A central consideration in traditional face-to-face therapies is the therapeutic alliance, whereas the nature of a digital therapeutic alliance and its relationship with outcomes requires further attention, particularly for individuals with serious mental illnesses. Objective This narrative

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Bremer, V., P. Chow, B. Funk, F. Thorndike, and L. Ritterband. "1204 Analyzing User Journey Data In Digital Health: Predicting Dropout From A Digital CBT-I Intervention." Sleep 43, Supplement_1 (2020): A460. http://dx.doi.org/10.1093/sleep/zsaa056.1198.

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Abstract Introduction Intervention dropout is an important factor for the evaluation and implementation of digital therapeutics, including in insomnia. Large amounts of individualized data (logins, questionnaires, EMA data) in these interventions can combine to create user journeys - the data generated by the path an individual takes to navigate the digital therapeutic. User journeys can provide insight about how likely users are to drop out of an intervention on an individual level and lead to increased prediction performance. Thus, the goal of this study is to provide a step-by-step guide fo

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Howarth, Michelle, Michaela Rogers, Neil Withnell, and Cath McQuarrie. "Growing spaces: an evaluation of the mental health recovery programme using mixed methods." Journal of Research in Nursing 23, no. 6 (2018): 476–89. http://dx.doi.org/10.1177/1744987118766207.

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Background Therapeutic horticulture is a nature-based method that includes a range of green activities, such as gardening, to promote wellbeing. It is believed that therapeutic horticulture provides a person-centred approach that can reduce social isolation for people with mental health problems. Aims The aim of the project was to evaluate the impact of a mental health recovery programme that used therapeutic horticulture as an intervention to reduce social inclusion and improve engagement for people with mental health problems. Methods A mixed-methods approach was used and data from four semi

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Rupert, Matthew P. "Evaluation of Sacroiliac Joint Interventions: A Systematic Appraisal of the Literature." Pain Physician 2;12, no. 2;3 (2009): 399–418. http://dx.doi.org/10.36076/ppj.2009/12/399.

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Background: The sacroiliac joint has been implicated as a source of low back and lower extremity pain. There are no definite historical, physical, or radiological features that can definitively establish a diagnosis of sacroiliac joint pain. Based on the present knowledge, an accurate diagnosis is made only by controlled sacroiliac joint diagnostic blocks. The sacroiliac joint has been shown to be a source of pain in 10% to 27% of suspected patients with chronic low back pain utilizing controlled comparative local anesthetic blocks. Study Design: A systematic review of diagnostic and therapeut

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Machado, Fernanda, Paula V. Nunes, Luciane F. Viola, Franklin S. Santos, Orestes V. Forlenza, and Mônica S. Yassuda. "Quality of life and Alzheimer's disease: Influence of participation at a rehabilitation center." Dementia & Neuropsychologia 3, no. 3 (2009): 241–47. http://dx.doi.org/10.1590/s1980-57642009dn30300011.

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Abstract Quality of life is seldom explored in evaluations of therapeutic interventions in Alzheimer's disease. Objective: To verify whether participation in a cognitive and functional rehabilitation program improves quality of life (QOL) among Alzheimer's disease (AD) patients. Methods: 19 AD patients participated in this study, 12 of whom attended 24 multi-professional intervention sessions - the experimental group - whereas the remaining 7 comprised the control group. The following tools were used to assess changes: a) Mini-Mental State Examination (MMSE); b) Geriatric Depression Scale (GDS

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Panzera, Michele, Daniela Alberghina, and Alessandra Statelli. "Ethological and Physiological Parameters Assessment in Donkeys Used in Animal Assisted Interventions." Animals 10, no. 10 (2020): 1867. http://dx.doi.org/10.3390/ani10101867.

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Background: Few studies have been performed to identify objective indicators for the selection of therapeutic donkeys or to assess their welfare during animal-assisted interventions (AAIs) Objective: This study aimed to evaluate the response to the ethological test and the modifications of physiological parameters in donkeys subjected to AAI sessions. Methods: Thirteen donkeys were subjected to a behavioral evaluation during an AAI session. Heart rate, heart rate variability, and root mean square of successive difference values were detected. Results: Statistically significant changes in the t

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Manchikanti, Laxmaiah. "Reassessment of Evidence Synthesis of Occupational Medicine Practice Guidelines for Interventional Pain Management." Pain Physician 4;11, no. 8;4 (2008): 393–482. http://dx.doi.org/10.36076/ppj.2008/11/393.

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Background: Appropriately developed practice guidelines present statements of best practice based on a thorough evaluation of the evidence from published studies on the outcomes of treatments, which include the application of multiple methods for collecting and evaluating evidence for a wide range of clinical interventions and disciplines. However, the guidelines are neither infallible, nor a substitute for clinical judgment. While the guideline development process is a complex phenomenon, conflict of interest in guideline development and inappropriate methodologies must be avoided. It has bee

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Flobak, Eivind, Emilie Sektnan Nordby, Frode Guribye, Robin Kenter, Tine Nordgreen, and Astri J. Lundervold. "Designing Videos With and for Adults With ADHD for an Online Intervention: Participatory Design Study and Thematic Analysis of Evaluation." JMIR Mental Health 8, no. 9 (2021): e30292. http://dx.doi.org/10.2196/30292.

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Background Adults with attention deficit hyperactivity disorder (ADHD) represent a heterogeneous group with both strengths and difficulties associated with the diagnosis. An online intervention attuned to their needs may improve their everyday functioning. When designing online interventions, it is important to adapt the therapeutic content to the values and needs of the target group. Objective This paper describes and evaluates a participatory process used to produce content for an online intervention for adults with ADHD by producing video vignettes clarifying core training principles ground

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Bubolz, Stefan, Gwendolyn Mayer, Nadine Gronewold, Thomas Hilbel, and Jobst-Hendrik Schultz. "Adherence to Established Treatment Guidelines Among Unguided Digital Interventions for Depression: Quality Evaluation of 28 Web-Based Programs and Mobile Apps." Journal of Medical Internet Research 22, no. 7 (2020): e16136. http://dx.doi.org/10.2196/16136.

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Background Web-based interventions for depression have been widely tested for usability and functioning. However, the few studies that have addressed the therapeutic quality of these interventions have mainly focused on general aspects without consideration of specific quality factors related to particular treatment components. Clinicians and scientists are calling for standardized assessment criteria for web-based interventions to enable effective and trustworthy patient care. Therefore, an extensive evaluation of web-based interventions at the level of individual treatment components based o

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Hansen, Hans C. "Sacroiliac Joint Interventions: A Systematic Review." Pain Physician 1;10, no. 1;1 (2007): 165–84. http://dx.doi.org/10.36076/ppj.2007/10/165.

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Background: The sacroiliac joint is a diarthrodial synovial joint with abundant innervation and capability of being a source of low back pain and referred pain in the lower extremity. There are no definite historical, physical, or radiological features to provide definite diagnosis of sacroiliac joint pain, although many authors have advocated provocational maneuvers to suggest sacroiliac joint as a pain generator. An accurate diagnosis is made by controlled sacroiliac joint diagnostic blocks. The sacroiliac joint has been shown to be a source of pain in 10% to 27% of suspected cases with chro

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Seely, Dugald, Julie K. Ennis, Ellen McDonell, and Linlu Zhao. "Naturopathic Oncology Care for Thoracic Cancers: A Practice Survey." Integrative Cancer Therapies 17, no. 3 (2018): 793–805. http://dx.doi.org/10.1177/1534735418759420.

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Background and Objectives: There is a lack of information on therapies recommended by naturopathic doctors (NDs) for lung and gastroesophageal cancer care. Study objectives were to: (1) identify the most common interventions considered for use by NDs; (2) identify interventions NDs recommend to support key therapeutic goals; and (3) identify potential contraindications between integrative and conventional therapies. Methods: Oncology Association of Naturopathic Physicians (OncANP) members (n = 351) were invited to complete an electronic survey. Respondents provided information on interventions

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Bambirra, Carla, Maria Cecília de Betsan Rodrigues, Christina Danielli Coelho de Morais Faria, and Fátima Rodrigues de Paula. "Clinical evaluation of balance in hemiparetic adults: a systematic review." Fisioterapia em Movimento 28, no. 1 (2015): 187–200. http://dx.doi.org/10.1590/0103-5150.028.001.ar03.

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Introduction Hemiparesis is a common post-stroke impairment often associated with balance deficits. Standardized instruments for balance assessment may be useful in identifying individuals at risk of falling and evaluating intervention outcomes. Objectives To identify instruments with adequate psychometric properties and clinical application to assess balance in hemiparetic cases within the scope of physiotherapy and to verify tools most frequently used in studies that evaluated the effects of therapeutic interventions in order to improve the balance of hemiparetic patients. Methods A search w

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Boswell, Mark V. "A Systematic Review of Therapeutic Facet Joint Interventions in Chronic Spinal Pain." Pain Physician 1;10, no. 1;1 (2007): 229–53. http://dx.doi.org/10.36076/ppj.2007/10/229.

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Background: Facet joints are considered to be a common source of chronic spinal pain. Facet joint interventions, including intraarticular injections, medial branch nerve blocks, and neurotomy (radiofrequency and cryoneurolysis) are used to manage chronic facet-mediated spinal pain. A systematic review of therapeutic facet interventions published in January 2005, concluded that facet interventions were variably effective for short-term and long-term relief of facet joint pain. Objective: To provide an updated evaluation of the effectiveness of 3 types of facet joint interventions in managing ch

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Laslett, Ben, and Mark Uphill. "An Online Intervention to Support Student-Athlete Mental Health: Implementation, Evaluation, and Critical Reflection." Case Studies in Sport and Exercise Psychology 4, S1 (2020): S1–54—S1–61. http://dx.doi.org/10.1123/cssep.2019-0048.

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This study examined the influence of two interventions (therapeutic letter to self; values targeting) on student-athletes’ mental health using two variants of a single-subject design: a multiple-baseline single-subject design and a probe design. Four high-ability student-athletes (two males and two females) who competed in various sports (e.g., soccer and cycling) completed two preintervention measures (Mental Health Continuum Short Form; Clinical Outcomes Routine Evaluation 10) at baseline. These measures were then readministered after Intervention 1, Intervention 2, and at a 2-week follow-up

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Wehmann, Eileen, Moritz Köhnen, Martin Härter, and Sarah Liebherz. "Therapeutic Alliance in Technology-Based Interventions for the Treatment of Depression: Systematic Review." Journal of Medical Internet Research 22, no. 6 (2020): e17195. http://dx.doi.org/10.2196/17195.

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Background There is growing evidence that technology-based interventions (TBIs) are effective for the treatment of depression. As TBIs are gaining acceptance, a question arises whether good therapeutic alliance, considered a key aspect of psychotherapy, can be established without or with minimal face-to-face contact or rather changes if blended concepts are applied. While therapeutic alliance has been studied extensively in the context of face-to-face therapy, only few studies have reviewed evidence on alliance ratings in TBIs. Objective The purpose of this study was to examine therapeutic all

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Daliri, Grunwald, Jobst, et al. "Endovascular treatment for chronic atherosclerotic occlusive mesenteric disease: Is stenting superior to balloon angioplasty?" Vasa 39, no. 4 (2010): 319–24. http://dx.doi.org/10.1024/0301-1526/a000056.

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Background: Endovascular treatment is an increasingly used therapeutic option in patients with chronic atherosclerotic occlusive mesenteric disease. Purpose of this study was evaluation of patency and mortality in patients treated with visceral artery percutaneous transluminal angioplasty (PTA) or stenting including follow-up. Patients and methods: A retrospective review of 17 consecutive patients (4 women, 13 men) with endovascular treatment for symptomatic chronic mesenteric ischemia from 1998 to 2004 was performed. Mean follow-up period was 42 months. Patient demographics, interventional de

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Uhlmann, Carmen, and Walter Fröscher. "Biofeedback as complementary treatment in patients with epilepsy – an underestimated therapeutic option? Review, results, discussion." Journal of Epileptology 24, no. 2 (2016): 173–80. http://dx.doi.org/10.1515/joepi-2016-0013.

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SummaryBackground.Biofeedback methods represent side effect free complementary options in the treatment of epilepsy. In this paper we review the current status of these methods in terms of clinical study results and their evaluation by systematic review papers. Possible mechanisms of action in biofeedback methods are discussed.Aim.To present the current status of biofeedback methods applied to patients with epilepsy.Material and Methods.With a literature search up to 10/2016 we screened publications containing the search terms “biofeedback”, “neurofeedback” or “neurotherapy” and “epilepsy” or

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La Touche, Roy, Sergio Martínez García, Beatriz Serrano García, et al. "Effect of Manual Therapy and Therapeutic Exercise Applied to the Cervical Region on Pain and Pressure Pain Sensitivity in Patients with Temporomandibular Disorders: A Systematic Review and Meta-analysis." Pain Medicine 21, no. 10 (2020): 2373–84. http://dx.doi.org/10.1093/pm/pnaa021.

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Abstract Objective To assess the effectiveness of cervical manual therapy (MT) on patients with temporomandibular disorders (TMDs) and to compare cervico-craniomandibular MT vs cervical MT. Design Systematic review and meta-analysis (MA). Methods A search in PubMed, EMBASE, PEDro, and Google Scholar was conducted with an end date of February 2019. Two independent reviewers performed the data analysis, assessing the relevance of the randomized clinical trials regarding the studies’ objectives. The qualitative analysis was based on classifying the results into levels of evidence according to the

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Martsevich, S. Yu, N. P. Kutishenko, Yu V. Lukina, M. M. Lukyanov, and O. M. Drapkina. "Clinical Trials Evaluating Drug Therapy: Types, Reliability of Results, Place in Modern Evidence-Based Medicine." Rational Pharmacotherapy in Cardiology 17, no. 2 (2021): 249–55. http://dx.doi.org/10.20996/1819-6446-2021-04-07.

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The article discusses the main methods of evidence in modern medicine. Special attention is paid to randomized controlled trials and observational studies. The advantages of randomized controlled trials over observational studies are considered. A comparison of the informative value of randomized controlled trials and observational studies in assessing the effect of therapeutic interventions is made. Attention is drawn to situations when conducting randomized controlled trials is not possible and when they become the main source of information. It is emphasized that in order to verify the resu

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Falco, Frank J. E. "Systematic Review of the Therapeutic Effectiveness of Cervical Facet Joint Interventions: An Update." Pain Physician 6;15, no. 6;12 (2012): E839—E868. http://dx.doi.org/10.36076/ppj.2012/15/e839.

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Background: The prevalence of chronic, recurrent neck pain is approximately 15% of the adult general population. Controlled studies have supported the existence of cervical facet or zygapophysial joint pain in 36% to 67% of these patients, when disc herniation, radiculitis, and discogenic are not pathognomic. However, these studies also have shown false-positive results in 27% to 63% of the patients with a single diagnostic block. There is also a paucity of literature investigating therapeutic interventions of cervical facet joint pain. Study Design: Systematic review of therapeutic cervical f

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Manchikanti, Laxmaiah. "A Critical Review of the American Pain Society Clinical Practice Guidelines For Interventional Techniques: Part 2. Therapeutic Interventions." Pain Physician 4;13, no. 4;7 (2010): E215—E264. http://dx.doi.org/10.36076/ppj.2010/13/e215.

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Background: Clinical guidelines are a constructive response to the reality that practicing physicians require assistance in assimilating and applying the exponentially expanding, often contradictory, body of medical knowledge. They attempt to define practices that meet the needs of most patients under most circumstances. Ideally, specific clinical recommendations contained within practice guidelines are systematically developed by expert panels who have access to all the available evidence, have an understanding of the clinical problem, and have clinical experience with the procedure being ass

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Spray, Jeffery W., and Marcia L. Brackbill. "Evaluation of the First International Normalized Ratio after Acute Care Discharge to the Primary Care Environment." Hospital Pharmacy 40, no. 7 (2005): 588–91. http://dx.doi.org/10.1177/001857870504000707.

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Purpose To determine the percentage of patients who maintain a therapeutic INR (international normalized ratio) when presenting for their first INR follow-up in the primary care setting after hospital discharge. Methods Prospective observational trial enrolling patients newly initiated on warfarin. Results Data for 35 patients were collected. Fifty-one percent of patients were therapeutic at their first follow-up lab visit with 23% subtherapeutic and 26% supratherapeutic. Conclusion A low percentage of patients were therapeutic and more intervention is necessary in the immediate post-discharge

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Vinluan, Celeste M., Melanie M. Jabalie, Jacquelyn P. Navarrete, and Margie E. Padilla. "Evaluating the Types of Pharmacy Student Interventions Made During an Interprofessional 6-Week Adult Internal Medicine Rotation." Journal of Pharmacy Practice 31, no. 3 (2017): 298–303. http://dx.doi.org/10.1177/0897190017707120.

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Introduction: The new standards for pharmacy education require that pharmacy students are involved in direct and interprofessional team-based care in multiple practice settings, which include “real-time” interactions with physician prescribers and medical students. Methods: From April 2014 to December 2015, fourth-year Doctor of Pharmacy (PharmD) students at University Medical Center of El Paso, Texas were assigned to an interprofessional team that was comprised of physician prescribers, medical students, and a pharmacist faculty. They recorded their interventions that were analyzed for type,

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Potemkowski, Andrzej. "The significance of NNT parameter for the evaluation of therapy effectiveness." Aktualności Neurologiczne 16, no. 4 (2016): 175–79. http://dx.doi.org/10.15557/an.2016.0022.

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Clinical trials provide a practicing clinician with an abundance if not excess of data to draw on when comparing treatment methods and deciding the potentially optimal therapeutic option for a given patient. NNT, or number needed to treat, has been identified as one of the parameters useful for assessing the effectiveness of therapy. It represents the number of patients who must undergo a given health-care intervention instead of another one to see a difference in the effectiveness of obtaining a desired outcome within a set timeframe. NNT is a derivative of absolute risk reduction (ARR) or in

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Martín-Valero, Rocio, Ana Maria Jimenez-Cebrian, Jose A. Moral-Munoz, Maria de-la-Casa-Almeida, Manuel Rodriguez-Huguet, and Maria Jesus Casuso-Holgado. "The Efficacy of Therapeutic Respiratory Muscle Training Interventions in People with Bronchiectasis: A Systematic Review and Meta-Analysis." Journal of Clinical Medicine 9, no. 1 (2020): 231. http://dx.doi.org/10.3390/jcm9010231.

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Background: Respiratory muscle dysfunction is an important health problem with high morbidity and mortality and associated costs in patients with bronchiectasis (BC). The aim of this study was to analyse the effects of therapeutic respiratory muscle training (RMT) interventions on improving sputum clearance, ventilator function, muscle strength and functional capacity in BC. Methods: Systematic review and meta-analysis were conducted following PRISMA guidelines. Two independent investigators searched using several electronic databases. The methodological quality of nine studies was assessed us

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Alderson, Hayley, Eileen Kaner, Rebecca Brown, et al. "Behaviour change interventions to reduce risky substance use and improve mental health in children in care: the SOLID three-arm feasibility RCT." Public Health Research 8, no. 13 (2020): 1–162. http://dx.doi.org/10.3310/phr08130.

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Background Looked-after children and care leavers (henceforth children in care) are young people placed under the care of local authorities, often because of a history of family abuse and/or neglect. These young people have significantly increased risk of substance use and mental health problems compared with peers. Aim The Supporting Looked After Children and Care Leavers In Decreasing Drugs, and alcohol (SOLID) trial aimed to investigate the feasibility of a definitive randomised controlled trial comparing two behaviour change interventions to reduce risky substance use (illicit drugs and al

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Zinck, Lindsey, Suzanne McGettigan, Jennifer Braun, Abbey Walsh, and Lauren Cullen. "The Oncology Evaluation Center: Implementation of a same-day evaluation and treatment center to avoid unnecessary ED visits." Journal of Clinical Oncology 37, no. 27_suppl (2019): 81. http://dx.doi.org/10.1200/jco.2019.37.27_suppl.81.

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81 Background: Oncology patients have high rates of both Emergency Department (ED) visits and readmissions. The Hematology-Oncology Division at this urban, 776-bed academic medical center established the Oncology Evaluation Center (OEC) to provide cancer patients with prompt ambulatory evaluation for new symptoms that may otherwise lead to ED visits and unplanned admissions. With new therapeutic options associated with unique complications, the OEC Advanced Practice Providers are knowledgeable in providing care to this high-risk population. ED providers can lack oncology-specific training, com

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Suryadevara, Manika, Kelly E. Steidl, Luke A. Probst, and Jana Shaw. "Inappropriate Vancomycin Therapeutic Drug Monitoring in Hospitalized Pediatric Patients Increases Pediatric Trauma and Hospital Costs." Journal of Pediatric Pharmacology and Therapeutics 17, no. 2 (2012): 159–65. http://dx.doi.org/10.5863/1551-6776-17.2.159.

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OBJECTIVES The objective of this study was to measure the appropriateness of vancomycin monitoring in a pediatric tertiary care center and to evaluate the effectiveness of two interventions, autonomous pharmacy therapeutic drug monitoring and health care provider education, in reducing avoidable pediatric patient trauma and hospital cost. METHODS A retrospective chart review evaluating vancomycin therapeutic drug monitoring (TDM) in pediatric inpatients was performed before and after the introduction of an autonomous pharmacy TDM program and health care provider (HCP) education. RESULTS Thirty

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Jati, Saket, Mohammad Danish, Tanveer Sheikh, and Ajay Varun. "Evaluation of therapeutic efficacy of epidural steroid injections in lumbar spine with patients of chronic low back pain." International Journal of Research in Orthopaedics 3, no. 6 (2017): 1218. http://dx.doi.org/10.18203/issn.2455-4510.intjresorthop20174717.

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<p class="abstract"><strong>Background:</strong> Intervertebral disc herniation, spinal stenosis, intervertebral disc degeneration without disc herniation, and post lumbar surgery syndrome are the most common diagnoses of chronic persistent low back and lower extremity symptoms, resulting in significant economic, societal, and health care impact. Epidural injections are one of the most commonly performed interventions in managing chronic low back pain (LBP) along with surgical intervention. Cost effectiveness and affordability has become the cornerstone of evidence-based medi

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La Marca, Roberto, Marko Nedeljkovic, Lizhuang Yuan, Andreas Maercker, and Ulrike Ehlert. "Effects of auricular electrical stimulation on vagal activity in healthy men: evidence from a three-armed randomized trial." Clinical Science 118, no. 8 (2010): 537–46. http://dx.doi.org/10.1042/cs20090264.

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The activity of the VN (vagus nerve) is negatively associated with risk factors such as stress and smoking, morbidity and mortality. In contrast, it is also a target of therapeutic intervention. VN stimulation is used in depression and epilepsy. Because of its high invasivity and exclusive application to therapy-resistant patients, there is interest in less invasive methods affecting the VN. Several studies examining acupuncture report beneficial effects on vagal activity. However, findings are inconsistent, and applied methods are heterogeneous resulting in difficulties in interpretation. The

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Morken, Ida Sund, Astrid Dahlgren, Ingeborg Lunde, and Siri Toven. "The effects of interventions preventing self-harm and suicide in children and adolescents: an overview of systematic reviews." F1000Research 8 (June 20, 2019): 890. http://dx.doi.org/10.12688/f1000research.19506.1.

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Background: Self-harm and suicide in children and adolescents are of serious consequence and increase during the adolescent years. Consequently, there is need for interventions that prevent such behaviour. The objective of this paper: to evaluate the effects of interventions preventing self-harm and suicide in children and adolescents in an overview of systematic reviews. Methods: We conducted a review of systematic reviews (OoO). We included reviews evaluating any preventive or therapeutic intervention. The quality of the included reviews was assessed independently, and data was extracted by

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Morken, Ida Sund, Astrid Dahlgren, Ingeborg Lunde, and Siri Toven. "The effects of interventions preventing self-harm and suicide in children and adolescents: an overview of systematic reviews." F1000Research 8 (February 18, 2020): 890. http://dx.doi.org/10.12688/f1000research.19506.2.

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Background: Self-harm and suicide in children and adolescents are of serious consequence and increase during the adolescent years. Consequently, there is need for interventions that prevent such behaviour. The objective of this paper: to evaluate the effects of interventions preventing self-harm and suicide in children and adolescents in an overview of systematic reviews. Methods: We conducted an overview of systematic reviews (OoO). We included reviews evaluating any preventive or therapeutic intervention. The methodological quality of the included reviews was assessed independently, and data

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Manchikanti, Laxmaiah. "A Systematic Review and Best Evidence Synthesis of Effectiveness of Therapeutic Facet Joint Interventions in Managing Chronic Spinal Pain." July 2015 18;4, no. 4;18 (2015): E535—E582. http://dx.doi.org/10.36076/ppj.2015/18/e535.

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Background: The therapeutic spinal facet joint interventions generally used for the treatment of axial spinal pain of facet joint origin are intraarticular facet joint injections, facet joint nerve blocks, and radiofrequency neurotomy. Despite interventional procedures being common as treatment strategies for facet joint pathology, there is a paucity of literature investigating these therapeutic approaches. Systematic reviews assessing the effectiveness of various therapeutic facet joint interventions have shown there to be variable evidence based on the region and the modality of treatment ut

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Bolton, Catherine, Christine Barrowclough, and Rachel Calam. "Parental Criticism and Adolescent Depression: Does Adolescent Self-Evaluation Act as a Mediator?" Behavioural and Cognitive Psychotherapy 37, no. 5 (2009): 553–70. http://dx.doi.org/10.1017/s1352465809990221.

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Background: A better understanding of relationships between adolescent depression and family functioning may help in devising ways to prevent development of depression and design effective therapeutic interventions. Aims: This study explored the relationship of parental emotional attitudes, (perceived criticism and expressed emotion) to adolescent self-evaluation and depression. Methods: A sample of 28 clinic-referred adolescents and their mothers participated. The Five Minute Speech Sample was used to measure parental expressed emotion, and the adolescents completed the Children's Depression

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Manchikanti, Laxmaiah. "Comprehensive Evidence-Based Guidelines for Interventional Techniques in the Management of Chronic Spinal Pain." Pain Physician 4;12, no. 4;7 (2009): 699–802. http://dx.doi.org/10.36076/ppj.2009/12/699.

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Background: Comprehensive, evidence-based guidelines for interventional techniques in the management of chronic spinal pain are described here to provide recommendations for clinicians. Objective: To develop evidence-based clinical practice guidelines for interventional techniques in the diagnosis and treatment of chronic spinal pain. Design: Systematic assessment of the literature. Methods: Strength of evidence was assessed by the U.S. Preventive Services Task Force (USPSTF) criteria utilizing 5 levels of evidence ranging from Level I to III with 3 subcategories in Level II. Outcomes: Short-t

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Ashford, Miriam Thiel, Ellinor K. Olander, and Susan Ayers. "Finding Web-Based Anxiety Interventions on the World Wide Web: A Scoping Review." JMIR Mental Health 3, no. 2 (2016): e14. http://dx.doi.org/10.2196/mental.5349.

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Background One relatively new and increasingly popular approach of increasing access to treatment is Web-based intervention programs. The advantage of Web-based approaches is the accessibility, affordability, and anonymity of potentially evidence-based treatment. Despite much research evidence on the effectiveness of Web-based interventions for anxiety found in the literature, little is known about what is publically available for potential consumers on the Web. Objective Our aim was to explore what a consumer searching the Web for Web-based intervention options for anxiety-related issues migh

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González-Saiz, Francisco, and Esperanza Vergara-Moragues. "In-Treatment Changes in Quality of Life-Related Variables in Therapeutic Communities for Cocaine Abusers: Are These Changes Associated with Clinical Outcomes?" International Journal of Environmental Research and Public Health 18, no. 14 (2021): 7442. http://dx.doi.org/10.3390/ijerph18147442.

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Background: Few studies have explored changes in quality of life during the first three months of admission to a therapeutic community for addictions. The objective of this study was to determine the relationship between these changes and treatment outcomes at discharge. Methods: We undertook a prospective longitudinal study of 142 cocaine-dependent patients treated at a therapeutics community. All of these patients reached the 3-month evaluation and were subsequently followed until discharge. All participants completed the following measures: Health-Related Quality of Life for Drug Abusers Te

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Zhang, Qing, Jing Gong, Haoxu Dong, Shabei Xu, Wei Wang, and Guangying Huang. "Acupuncture for chronic fatigue syndrome: a systematic review and meta-analysis." Acupuncture in Medicine 37, no. 4 (2019): 211–22. http://dx.doi.org/10.1136/acupmed-2017-011582.

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Objective: To evaluate evidence for the efficacy of acupuncture for chronic fatigue syndrome (CFS). Methods: Randomized controlled trials (RCTs) comparing acupuncture with sham acupuncture, other interventions that may have a therapeutic effect, or no intervention, for the treatment of CFS, were searched for in the following databases up to March 2018: Pubmed; Embase; the Cochrane Library; Web of Science; Wanfang database; China National Knowledge Infrastructure (CNKI); Chinese Biomedicine (CBM) database; and VIP database. Risk of bias was determined using the Cochrane tool. Meta-analyses were

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Elbreder, Márcia Fonsi, Rebeca de Souza e. Silva, and Ronaldo Laranjeira. "Alcohol-dependent patients receiving specialised outpatient care: an overview of gender issues." Jornal Brasileiro de Psiquiatria 59, no. 1 (2010): 24–27. http://dx.doi.org/10.1590/s0047-20852010000100004.

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OBJECTIVE: The objective of the present study, with focus on gender, was aimed at evaluating alcohol-dependent individual in terms of socio-demographic variables related to alcohol consumption and therapeutic interventions. METHODS: This is a retrospective cross-sectional study of 1,051 patients (833 men and 218 women), with diagnosis of alcohol dependence syndrome, according to ICD-10 criteria, who had sought treatment for the first time at a specialised health centre between 2000 and 2006. RESULTS: The results showed that women, compared to men, are more likely to be unemployed and without p

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Kurtaş, Ömer, Şükriye Boşgelmez, İrem Yaluğ, et al. "The Evaluation of Suicide Letters in Turkey From a Cognitive Perspective." Crisis 33, no. 2 (2012): 73–79. http://dx.doi.org/10.1027/0227-5910/a000112.

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Background: Different methods are used to understand the suicidal mind. Suicide note analysis may be most direct way to do this. Aims: To study the content of suicide letters under forensic evaluation in terms of psychological and cognitive aspects. Methods: A total of 51 letters were referred to The Council of Forensic Medicine from different cities of Turkey and analyzed by a research group with ten members including forensic medicine specialists and psychiatrists. The Questionnaire of Content Analysis of Suicide Letters (The Q-CAS), developed by researchers, was used to analyze the cognitiv

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Wolny, Tomasz. "The Use of Neurodynamic Techniques in the Conservative Treatment of Carpal Tunnel Syndrome – a Critical Appraisal of the Literature." Ortopedia Traumatologia Rehabilitacja 19, no. 5 (2017): 0. http://dx.doi.org/10.5604/01.3001.0010.5822.

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Background. Carpal tunnel syndrome (CTS) is the most common peripheral neuropathy, characterized by the presence of many sensory and motor abnormalities. In the physiotherapy of patients with CTS, neurodynamic techniques are very common, while the scientific literature does not show clear evidence of beneficial effects obtained by using these techniques. Therefore, the aim of this work was to critically evaluate the use of neurodynamic techniques in the conservative treatment of CTS. Material and methods. Three electronic databases (MEDLINE, SCOPUS and POL-index) and Google Scholar were queri

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Werneck, Lineu Cesar, Paulo José Lorenzoni, Renata Dal-Prá Ducci, Otto Hernández Fustes, Cláudia Suemi Kamoi Kay, and Rosana Herminia Scola. "Duchenne muscular dystrophy: an historical treatment review." Arquivos de Neuro-Psiquiatria 77, no. 8 (2019): 579–89. http://dx.doi.org/10.1590/0004-282x20190088.

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ABSTRACT In this review, we discuss the therapies used in the treatment of patients with Duchenne muscular dystrophy since the first description of the disease. A short description is given of the various theories based on disease pathogenesis, which give the substrates for the many therapeutic interventions. A brief review of the methods of evaluation used in therapeutic trials is made. Of all the treatments, the only drugs that are still considered able to modify the course of the disease are the corticosteroids (prednisone/prednisolone/deflazacort). Other drugs (coenzyme Q10 and creatine) h

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Dunn, Graham, Richard Emsley, Hanhua Liu, et al. "Evaluation and validation of social and psychological markers in randomised trials of complex interventions in mental health: a methodological research programme." Health Technology Assessment 19, no. 93 (2015): 1–116. http://dx.doi.org/10.3310/hta19930.

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BackgroundThe development of the capability and capacity to evaluate the outcomes of trials of complex interventions is a key priority of the National Institute for Health Research (NIHR) and the Medical Research Council (MRC). The evaluation of complex treatment programmes for mental illness (e.g. cognitive–behavioural therapy for depression or psychosis) not only is a vital component of this research in its own right but also provides a well-established model for the evaluation of complex interventions in other clinical areas. In the context of efficacy and mechanism evaluation (EME) there i

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Qu, Chengcheng, Corina Sas, Claudia Daudén Roquet, and Gavin Doherty. "Functionality of Top-Rated Mobile Apps for Depression: Systematic Search and Evaluation." JMIR Mental Health 7, no. 1 (2020): e15321. http://dx.doi.org/10.2196/15321.

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Background In the last decade, there has been a proliferation of mobile apps claiming to support the needs of people living with depression. However, it is unclear what functionality is actually provided by apps for depression, or for whom they are intended. Objective This paper aimed to explore the key features of top-rated apps for depression, including descriptive characteristics, functionality, and ethical concerns, to better inform the design of apps for depression. Methods We reviewed top-rated iPhone OS (iOS) and Android mobile apps for depression retrieved from app marketplaces in spri

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Ibáñez-Garcia, Sara, Carmen Rodriguez-Gonzalez, Vicente Escudero-Vilaplana, et al. "Development and Evaluation of a Clinical Decision Support System to Improve Medication Safety." Applied Clinical Informatics 10, no. 03 (2019): 513–20. http://dx.doi.org/10.1055/s-0039-1693426.

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Background Clinical decision support systems (CDSSs) are a good strategy for preventing medication errors and reducing the incidence and severity of adverse drug events (ADEs). However, these systems are not very effective and are subject to multiple limitations that prevent their implementation in clinical practice. Objectives The objective of this study was to evaluate the effectiveness of an advanced CDSS, HIGEA, which generates alerts based on predefined clinical rules to identify patients at risk of an ADE. Methods A multidisciplinary team defined the system and the clinical rules focusin

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