Relevant bibliographies by topics / Evolution – Methodology

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Evolution – Methodology'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Evolution – Methodology"

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Harrington, H. James, Frank Voehl, Boris Zlotin, and Alla Zusman. "The Directed Evolution methodology." TQM Journal 24, no. 3 (April 20, 2012): 204–17. http://dx.doi.org/10.1108/17542731211226736.

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Greene, Jennifer C., and Charles McCIintock. "The evolution of evaluation methodology." Theory Into Practice 30, no. 1 (January 1991): 13–21. http://dx.doi.org/10.1080/00405849109543471.

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Newsome, W. Harvey. "An Evolution of Pesticide Residue Methodology." Journal of AOAC INTERNATIONAL 78, no. 1 (January 1, 1995): 4–8. http://dx.doi.org/10.1093/jaoac/78.1.4.

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RAJLICH, VÁCLAV. "MSE: A Methodology for Software Evolution." Journal of Software Maintenance: Research and Practice 9, no. 2 (March 1997): 103–24. http://dx.doi.org/10.1002/(sici)1096-908x(199703)9:2<103::aid-smr146>3.0.co;2-n.

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Short, KW. "Methodology integration: evolution of information engineering." Information and Software Technology 33, no. 9 (November 1991): 720–32. http://dx.doi.org/10.1016/0950-5849(91)90045-d.

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Sabah AlFedaghi. "Toward a New Methodology of Software Evolution." Journal of Next Generation Information Technology 3, no. 4 (November 30, 2012): 78–87. http://dx.doi.org/10.4156/jnit.vol3.issue4.8.

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Boros, James. "The Evolution of Robert Moevs's Compositional Methodology." American Music 8, no. 4 (1990): 383. http://dx.doi.org/10.2307/3051761.

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de Boer, Bart. "Towards a methodology of language evolution modelling." Physics of Life Reviews 11, no. 2 (June 2014): 307–8. http://dx.doi.org/10.1016/j.plrev.2014.01.003.

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Rasnitsyn, A. P. "Ontology of evolution and methodology of taxonomy." Paleontological Journal 40, S6 (December 2006): S679—S737. http://dx.doi.org/10.1134/s003103010612001x.

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Chang, Ellis, and Allen Park. "Evolution of Wafer Inspection and Review Methodology." ECS Transactions 18, no. 1 (December 18, 2019): 183–86. http://dx.doi.org/10.1149/1.3096447.

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Dissertations / Theses on the topic "Evolution – Methodology"

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Elamvazuthi, Chandran. "The evolution of the PCSC methodology and its toolset." Thesis, University of Sheffield, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296816.

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Veeger, Anne Isabella 1961. "Geochemical methods for evaluating the origin and evolution of ground water in volcanic rocks." Diss., The University of Arizona, 1991. http://hdl.handle.net/10150/191168.

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A broad-based geochemical approach, including chemical and isotopic analyses of ground water, chemical analysis of aquifer materials, and laboratory water-rock experiments, was used to evaluate the origin and chemical evolution of ground water on La Palma, a volcanic island in the Canary Archipelago. Stable isotopes of oxygen, hydrogen, carbon and sulfur were successfully used to delineate recharge zones and identify solute sources. Laboratory study of water-rock interactions established the source of solutes and the nature of the chemical reactions that control ground-water chemistry. Most ground water on La Palma originates in a recharge zone that encircles the island from 500 to 1800 meters above sea level. Dry fallout and seaspray are minor sources of solutes, however, evaporative concentration during recharge may produce elevated chloride levels in some portions of the island. Laboratory water-rock experiments and ground-water analyses indicate that incongruent dissolution of aluminosilicate minerals is the dominant process of solute acquisition. The geochemical evolution of most waters is controlled by the availability of dissolved carbon dioxide gas. However, oxidation of pyrite enhances the reactivity of ground water in some portions of the island. Waters in the early phases of chemical evolution appear to be in equilibrium with a kaolinite alteration product, whereas more mineralized waters have compositions consistent with smectite equilibrium. Zones or compartments of ground-water flow were delineated by classifying sampling sites into geochemically distinct groups. Eight distinct zones of ground-water flow were identified using these criteria, including superimposed but hydrologically separate flow paths.
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Kuvaja, P. (Pasi). "Software process capability and maturity determination:BOOTSTRAP methodology and its evolution." Doctoral thesis, Oulun yliopisto, 2012. http://urn.fi/urn:isbn:9789526200309.

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Abstract Software process assessment and improvement came under the spotlight in the discussion of software engineering when the Software Engineering Institute published the maturity model for software process capability determination in 1987. Since then, several new approaches and standards have been developed. This thesis introduces a European software process assessment and improvement methodology called BOOTSTRAP, which was initially developed in an ESPRIT project starting from lean and kaizen philosophy. The focus is on the evolution of methodology and how it was developed, using an experimental research approach. The work covers also enhancements to the methodology investigated in the SPICE, PROFES and TAPISTRY projects. The enhancements expand the original methodology into new specific application areas, keep it compliant with new quality standards and certification, improve the efficiency of the assessment method, enhance the focus from process to product and strengthen improvement monitoring and support. To address these areas, the new BOOTSTRAP methodology releases offer tailored and enhanced assessment reference models and enhanced assessment and improvement methods. The new features also facilitate more frequent and even continuous assessments with software measurement-based indicators. The thesis explains the origin and features of BOOTSTRAP software process assessment and improvement methodology and how it was developed for professional use. The discussion starts with the evolution of the methodology. Then the new trends and demands are introduced and new features of the BOOTSTRAP methodology described. The conclusion discusses how the methodology developed to be able successfully to support professional software process assessment, to align it with the evolution of software engineering, to adopt the features and requirements of the underlying standards in order to conform to the requirements set by ISO 15504 standard and to become validated in practice
Tiivistelmä Ohjelmistoprosessin arvioinnista ja parantamisesta tuli ohjelmistotekniikan keskeinen kiinnostuksen kohde kun Carnegie-Mellon yliopiston ohjelmistotekniikan instituutti SEI julkaisi kypsyysmallinsa ohjelmistoprosessin kyvykkyyden arviointiin vuonna 1987. Siitä lähtien maailmalla on syntynyt lukuisa määrä uusia malleja ja standardeja tälle alueelle. Tässä väitöskirjassa esitellään eurooppalainen ohjelmistoprosessin arviointi- ja parantamismenetelmä BOOTSTRAP, joka kehitettiin alun perin Euroopan unionin ESPRIT tutkimusohjelman rahoittamassa projektissa lähtien japanilaisesta ohut-ajattelusta (Lean) ja sen jatkuvan parantamisen periaatteesta (Kaizen). Esitys keskittyy menetelmän kehittymiseen ja siihen miten menetelmä käytännössä kehitettiin käyttäen kokeellista tutkimustapaa teollisessa ympäristössä. Työ kattaa myös alkuperäiseen menetelmään tehdyt laajennukset, jotka syntyivät yhteistyössä SPICE, PROFES ja TAPISTRY projekteissa tehdyn tutkimuksen tuloksena. Tehdyt laajennukset mahdollistavat menetelmän käytön uusilla sovellusalueilla, takaavat menetelmän yhteensopivuuden alan laatu- ja sertifiointistandardien kanssa, parantavat menetelmän tehokkuutta, laajentavat menetelmän käyttöaluetta prosessin arvioinnista sisältämään myös tuotteen kehittämisen arvioinnin ja vahvistavat parantamisen seurantaa ja tukemista. Toteuttaakseen näiden uusien ominaisuuksien vaatimukset uudet BOOTSTRAP menetelmän julkistukset tarjoavat räätälöityjä ja laajennettuja mallikuvauksia arviointien tekemiseksi sekä entistä täydellisempiä lähestymistapoja arviointien suorittamiselle ja parantamiselle. Menetelmän uudet ominaisuudet mahdollistavat myös usein toistuvien arviointien suorittamisen ja jopa jatkuvan arvioinnin ohjelmisto-mittauksia hyödyntäen. Väitöskirjassa kuvataan yksityiskohtaisesti BOOTSTRAP menetelmän lähtö-kohdat ja ominaisuudet ja se kuinka menetelmä onnistuttiin kehittämään ammattimaiseen ohjelmistoprosessin arviointiin ja parantamiseen sopivaksi. Ensin kuvataan menetelmän kehittyminen ja sitten edetään alan uusien kehitystrendien ja vaatimusten esittelyyn siihen kuinka BOOTSTRAP menetelmä uudet ominaisuudet vastaavat näihin vaatimuksiin. Yhteenvedossa osoitetaan kuinka kehittämisessä onnistuttiin saamaan aikaan uusi menetelmä, joka sopii ammattimaiseen ohjelmistoprosessin arviointiin, vastaa kaikilta osin alan kehittymisen vaatimuksia, sisältää alan standardien vaatimukset täyttävät käytännössä koestetut ominaisuudet, jotka takaavat menetelmän vastaavuuden ISO 15504 standardin vaatimuksiin
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Cunha, Gabriel Oliva Costa. "Hayek and complexity: coordination, evolution and methodology in social adaptive systems." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/12/12138/tde-06072016-152628/.

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The affinity between the work of the Austrian economist Friedrich A. Hayek and the approach of Complexity Economics is widely recognized by the literature. In spite of this, there still is a lack of studies that seek to analyze in depth the relationship between Hayek and complexity. This dissertation is a contribution to the filling of this large gap in the literature. In the first part of the work, we analyze the various periods in the development of Hayek\'s vision of complexity, showing that this vision is strongly present in his works on knowledge, competition, methodology, evolution, and spontaneous order. In the second part, we explore how Hayek was influenced by two of the main precursors of modern complexity theory - cybernetics and general system theory - from the time he was working on his book on theoretical psychology, The Sensory Order (1952), until the end of his intellectual career.
A afinidade entre a obra do economista austríaco Friedrich A. Hayek e a abordagem da Economia e Complexidade é amplamente reconhecida pela literatura. Apesar disso, ainda há grande carência de estudos que busquem analisar de forma aprofundada a relação entre Hayek e a complexidade. Esta dissertação é uma contribuição para o preenchimento dessa grande lacuna na literatura. Na primeira parte do trabalho, os diversos períodos no desenvolvimento da visão de complexidade de Hayek são analisados, evidenciando-se como tal visão está fortemente presente em seus trabalhos sobre conhecimento, competição, metodologia, evolução e ordem espontânea. Na segunda parte, exploramos como Hayek foi influenciado por dois dos principais precursores da moderna teoria da complexidade - a cibernética e a teoria geral do sistema - desde o período em que estava trabalhando no seu livro sobre psicologia teórica, The Sensory Order (1952), até o final de sua carreira intelectual.
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Cencerrado, Barraqué Andrés. "Methodology for time response and quality assessment in natural hazards evolution prediction." Doctoral thesis, Universitat Autònoma de Barcelona, 2012. http://hdl.handle.net/10803/284023.

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En aquesta tesi doctoral es descriu una metodologia per a l’evaluació del temps de resposta i la qualitat en la predicció de l’evolució d’emergències mediambientals. El treball s’ha centrat en el cas específic dels incendis forestals, com un dels desastres naturals més importants i devastadors, però és facilment extrapol·lable a altre tipus d’emèrgencies mediambientals. Existeixen molts entorns de predicció que es basen en l’ús de simuladors de l’evolució del fenòmen catastròfic. Donat el creixent poder quant a capacitat de cómput que ens ofereixen els nous progressos computacionals, com les arquitectures multicore i manycore, i inclús els paradigmes de cómput distribuit, com Grid o Cloud Computing, sorgeix la necessitat d’explotar encertadament el poder computacional que aquests ens ofereixen. Aquest objectiu s’assoleix proporcionant la capacitat d’avaluar, per endavant, com les restriccions existents en el moment d’atendre un incendi forestal actiu afectaran als resultats que s’obtindran, en termes de qualitat (precisió) obtinguda, i temps necessari per prendre una decisió, i en conseqüència, tenir la capacitat de escollir la configuració més adient tant de l’estratègia de predicció, com dels recursos computacionals. Com a conseqüència, el sistema que deriva de l’aplicació d’aquesta metodologia no està dissenyat per ser un Sistema de Suport a les Decisions (DSS), però sí una eina de la que la majoria de DSSs per incendis forestals es poden beneficiar notablement. El problema s’ha tractat per mitjà de la caracterització del comportament d’aquests dos factors durant el procés de predicció. Per això, es presenta un mètode de predicció de dues etapes i s’utilitza com a base de treball, donat el notable augment de qualitat que proporciona en les prediccions. Aquesta metodologia implica haver de treballar amb tècniques pròpies del camp de la Intel.ligència Artificial, com són els Algorismes Genètics i els Arbres de Decisió, i també es recolza en un intens estudi estadístic de les bases de dades d’entrenament, compostes pels resultats de milers de simulacions. Els resultats obtinguts en aquest treball d’investigació de llarga durada són completament satisfactoris, i obren camí a nous reptes. A més, la flexibilitat que ofereix aquesta metodologia permet aplicar-la en qualsevol altre context d’emergència, el qual la converteix en una destacable i molt útil eina per lluitar contra aquestes catàstrofes.
En esta tesis doctoral se describe una metodología para la evaluación del tiempo de respuesta y la calidad en la predicción de la evolución de emergencias medioambientales. El trabajo se ha centrado en el caso específico de los incendios forestales, como uno de los desastres naturales más importantes y devastadores, pero es fácilmente extrapolable a otro tipo de emergencias medioambientales. Existen muchos entornos de predicción que se basan en el uso de simuladores de la evolución del fenómeno catastrófico. Dado el creciente poder en cuanto a capacidad de cómputo que nos ofrecen los nuevos avances computacionales, como las arquitecturas multicore y manycore, e incluso los paradigmas de cómputo distribuido, como Grid o Cloud Computing, surge la necesidad de ser capaces de explotar acertadamente el poder computacional que éstos nos ofrecen. Tal objetivo se alcanza proporcionando la capacidad de evaluar, de antemano, cómo las restricciones existentes a la hora de atender un incendio forestal activo afectarán a los resultados que se obtendrán, tanto en términos de calidad (precisión) obtenida, y tiempo necesario para tomar una decisión, y por consiguiente, tener la capacidad de escoger la configuración más adecuada tanto de la estrategia de predicción, como de los recursos computacionales. Como consecuencia, el sistema que deriva de la aplicación de esta metodología no está diseñado para ser un Sistema de Soporte a las Decisiones (DSS), pero sí una herramienta de la que la mayoría de DSSs para incendios forestales se pueden beneficiar notablemente. El problema se ha tratado por medio de la caracterización del comportamiento de estos dos factores durante el proceso de predicción. Para ello, un método de predicción de dos etapas es presentado y utilizado como base de trabajo, dado el notable aumento de calidad que proporciona en las predicciones. Esta metodología implica lidiar con técnicas propias del campo de la Inteligencia Artificial, como son los Algoritmos Genéticos y los Árboles de Decisión, y a su vez se apoya en un intenso estudio estadístico de bases de datos de entrenamiento, compuestas por los resultados de miles de distintas simulaciones. Los resultados obtenidos en este trabajo de investigación a largo plazo son completamente satisfactorios, y abren camino a nuevos retos. Además, la flexibilidad que ofrece la metodología permite aplicarla en cualquier otro contexto de emergencia, lo que la convierte en una destacable y muy útil herramienta para luchar contra estas catástrofes
This thesis describes a methodology for time response and quality assessment in natural hazards evolution prediction. This work has been focused on the specific case of forest fires as an important and worrisome catastrophe, but it can easily be extrapolated to all other kinds of natural hazards. There exist many prediction frameworks based on the use of simulators of the evolution of the hazard. Given the increasing computing capabilities allowed by new computing advances such as multicore and manycore architectures, and even distributed-computing paradigms, such as Grid and Cloud Computing, the need arises to be able to properly exploit the computational power they offer. This goal is fulfilled by introducing the capability to assess in advance how the present constraints at the time of attending to an ongoing forest fire will affect the results obtained from them, both in terms of quality (accuracy) obtained and time needed to make a decision, and therefore being able to select the most suitable configuration of both the prediction strategy and computational resources to be used. As a consequence, the framework derived from the application of this methodology is not supposed to be a new Decision Support System (DSS) for fire departments and Civil Protection agencies, but a tool from which most of forest fire (and other kinds of natural hazards) DSSs could benefit notably. The problem has been tackled by means of characterizing the behavior of these two factors during the prediction process. For this purpose, a two-stage prediction framework is presented and considered as a suitable and powerful strategy to enhance the quality of the predictions. This methodology involves dealing with Artificial Intelligence techniques, such as Genetic Algorithms and Decision Trees and also relies on a strong statistical study from training databases, composed of the results of thousands of different simulations. The results obtained in this long-term research work are fully satisfactory, and give rise to several new challenges. Moreover, the flexibility offered by the methodology allows it to be applied to other kinds of emergency contexts, which turns it into an outstanding and very useful tool in fighting against these catastrophes.
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Subt, Cristina. "Resolving chronological and temperature constraints on Antarctic deglacial evolution through improved dating methodology." Scholar Commons, 2017. https://scholarcommons.usf.edu/etd/7447.

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In order to determine the timing of Antarctic ice sheet retreat and advance during the Late Quaternary, various tools are used to measure the age of marginal marine sediments. Carbonate 14C dating is a well-established approach, but requires foraminiferal microfossils, shells or other carbonate materials that are rare in most Antarctic regions, and may also suffer from vital effects, which can result in variability of up to 500 years in living organisms. Bulk acid insoluble organic (AIO) 14C dates are frequently as an alternative, but this approach works best where high productivity and sedimentation rates reign, and not too well in condensed sequences where high proportions of detritus are present. Compound specific dating methods have also been employed, but these may still yield an average age from a mixture of components and require very large sample sizes. Alternate methods of applying a chronology have also been used, such as magnetic intensity dating, or regional correlation with well-dated cores, but these may not always provide accurate and precise dates. Here I present work, some published with co-authors, of progressive improvements of Ramped PyrOx 14C dating, which utilizes the thermochemical degradation of components within a bulk AIO sediment sample. This dissertation focuses on the study, improvement and application of advanced Ramped PyrOx techniques. These improvements include novel techniques, such as compositing and isotope dilution that I use to date sediments where the proportion of contemporaneously deposited carbon is very small relative to other detrital components, and maximize the accuracy of resulting dates while minimizing costs in precision from utilizing ultra-small fractions of the bulk sample. Ramped PyrOx 14C dating techniques allows us to generate chronologies for cores that would otherwise go undated. Furthermore, these techniques can be used to push the limits of radiocarbon dating not only to regions where accurate core chronologies have been difficult to come by, but also further back in time, into marine sediment horizons deposited at or before the last glacial maximum (LGM), where highly detrital material has precluded radiocarbon dating in the past. Wider use of these techniques can enable more coordinated a priori coring efforts to constrain regional glacial responses to rapid warming.
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Lawniczek, Baptiste. "Evolution of the methodology of weight estimation and engine feasibility in preliminary design." Thesis, KTH, Flygdynamik, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-261216.

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Som en del av Aerospace Engineering masterprogrammet som jag följde på KTH från augusti 2017 till juni 2018, fick jag slutligen en självständig studie i form av ett avhandlingsprojekt. Jag fick möjlighet att slutföra mitt 6-månaders examensprojekt på Safran Aircraft Engines i Villaroche, Frankrike.  Safran är en internationell högteknologisk grupp som arbetar inom flygplanets framdrivning och utrustning, rymd- och försvarsmarknader. Som en del av de mekaniska aktiviteter som genomförs vid Produkt Innovation Lab är genomförandet av en för-dimensioneringsmetod för motorkonstruktioner nödvändiga för att få en uppfattning om för-dimensionering tidigare inom projektet och inom en rimlig tidsrymd. Huvudsyftet med detta projekt är att utveckla metoden som gör det möjligt att göra viktstatus och genomförbarhetsbedömningar av motorramkomponenterna i en preliminär konstruktionsfas och inom en begränsad tid. Detta papper fokuserar mer exakt på en äldre kommersiell motor mellanram. Denna metod måste leda till att en konsekvent modell skapas som ligger närmare kraven och specifikationerna. Slutsatsen av rapporten är att den implementerade pre-designmetoden möjliggör resultat med avseende på viktstatus och genomförbarhet som överensstämmer med specifikationerna. Vidare är beräkningstiden i linje med förväntningarna. Detta projekt har äntligen tillåtit att skapa en modell som kommer att tas som referens för att utveckla och designa nya motorer som har en konfiguration som liknar äldre kommersiella motorer.
This paper aims to develop and to validate a methodology to realize pre-sizing studies on aircraft engine structural frames for Safran Aircraft Engines Product Innovation Lab activities. The members of this team are in charge of creating new propulsion systems architectures in accordance with product strategy guidelines or airframer needs. Aerospace industry being highly competitive, the Product Innovation Lab must be able to respond quickly and precisely to any demand emerging from aircraft manufacturers or strategy team.The main purpose of this project is to improve the methodology permitting to make weight status and feasibility estimations of the engine frame components in a preliminary design phase and in a limited amount of time. This methodology must lead to the creation of a consistent model that is closer to the requirements and specifications imposed. This paper more precisely focus on legacy commercial engine structural frame. Reflection has been conducted on the creation of a simplified parametrized model of an existing commercial engine structural frame and on the way to mesh it in order to find a good compromise between results fidelity and computation time. Regarding the weight status and feasibility results obtained with a first model, an optimization of the model configuration has finally been conducted in order to get results that fit with the specifications.Conclusion of the report is that the pre-sizing methodology can be adapted to existing commercial engine structural frame configuration. Results obtained in terms of weight status and feasibility are in accordance with the specifications and the computation time is in agreement with the expectations. It has permitted to create a model that will be taken as a reference to develop and design new engines having a configuration similar to the legacy commercial engine considered in this study. For that purpose, iterations and optimizations will be conducted on the simplified model implemented during the project in order to determine a new configuration of the pre-sized intermediate frame model which sticks with reality i.e. that respects the provided feasibility specifications.Note that due to the public nature of this report, sensitive information and data used and obtained during the project have been removed from the present paper. Nevertheless, the methodology followed has been presented and discussed in detail. Relative deviations between the results obtained and reference values have also been exposed in order to give the reader an idea of implemented model consistency.
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Wilcke, Juliane Charlotte. "An evaluation of means of inquiry into the biological evolution of consciousness." Thesis, University of Canterbury. Department of Psychology, 2010. http://hdl.handle.net/10092/5070.

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How can the biological evolution and functions of consciousness be studied? The purpose of this thesis was to determine not only what means of inquiry are available to do so but also how good they are or, more specifically, how promising they are with respect to the research goal of giving a scientifically respectable evolutionary explanation of consciousness. Because no suitable or easily adaptable evaluation system or set of evaluative criteria was available, I constructed a systematic tool for evaluating the promise of means of inquiry. The evaluation tool has three dimensions--relevance, efficacy, and practicality--with two criteria each, which are assessed independently (except for the relevance criteria) and synthesised into dimensional and promise scores. This tool served to evaluate, and advise on, 23 means of inquiry that have been used in the investigation of the evolution of consciousness, including its adaptation status and evolutionary functions. The core of the thesis is formed by the evaluation tool and its application. After establishing the need for an evaluation of means of inquiry in this area and presenting the evaluation tool constructed for this purpose, I apply the tool to arguments that consciousness is an evolutionary adaptation, to general reasoning strategies, and to evolutionary strategies. This thesis core is preceded by a contextual introduction to consciousness and evolutionary theory and by the dismissal of some sceptical positions. It is followed by a comparative review of the evaluation results and an evaluation of the evaluation tool. The main contributions of this research consist of the promise evaluation tool for means of inquiry, which is underpinned by a new evaluative theory and available for use by other researchers; and, through the tool's application, an improved understanding of means of inquiry and recommendations about which of them to use for the present research goal.
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King, Scott B. "Evolution of methodology for obtaining hydrogen magnetic resonance spectra of thyroid nodules in vivo." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0018/NQ45004.pdf.

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Choi, Yoon-Aa. "Molecular engineering of new protein labeling methodology based on rational design and in vitro evolution." Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/57981.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2010.
Cataloged from PDF version of thesis. Vita.
Includes bibliographical references.
Site-specific labeling using E coli biotin ligase (BirA) and its 15-amino acid "acceptor peptide" (AP) has been applied to study the function of various cellular proteins. In order to extend the capabilities of biotin ligase-based labeling, we engineered key elements of the labeling platform. First we characterized a novel peptide substrate (called "yeast acceptor peptide" (yAP)) for yeast biotin ligase (yBL) that had been evolved by phage display. Assays performed in vitro and on the yeast surface showed that the yBL/yAP pair was orthogonal to the BirA/AP pair, allowing two-color labeling of different proteins on cells with differently-colored probes. Second, to improve the kinetic efficiency of yAP, we developed a novel selection scheme based on yeast display. Model selections demonstrated up to 1000-fold enrichment, and three rounds of selection on a randomized peptide library were performed. Third, we attempted to improve the kinetic efficiency of BirA through evolution by in vitro compartmentalization (IVC). Because the original IVC protocol based on bead-linked DNA had many technical problems, we developed a novel bead-less IVC protocol. An enrichment factor of 25 was obtained in a model selection. Due to the single-turnover nature of the selection, however, this scheme was not able to enrich highly active catalysts over moderately active ones. In separate work, we turned our attention to the streptavidin-biotin pair. Again using bead-less IVC, we performed a selection for streptavidin mutants that could bind a ketone analog of biotin with high affinity.
(cont.) Two rounds of selection were performed but characterization of enriched clones was not completed. Finally, we helped to discover a mutant ligase that could catalyze attachment of a fluorinated aryl azide photocrosslinker to proteins fused to a 17-amino acid peptide tag. The aryl azide probe was tested and shown to be accepted by a W37V mutant of E coli lipoic acid ligase (LplA).
by Yoon-Aa Choi.
Ph.D.
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Books on the topic "Evolution – Methodology"

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service), SpringerLink (Online, ed. The Evolution of Macroeconomic Theory and Policy. Berlin, Heidelberg: Springer-Verlag Berlin Heidelberg, 2009.

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Social evolution and sociological categories. London: Routledge, 2010.

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Knowledge, institutions, and evolution in economics. London: Routledge, 1999.

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Oeser, Erhard. Evolution und Selbstkonstruktion des Rechts: Rechtsphilosophie als Entwicklungstheorie der praktischen Vernunft. Wien: Böhlau, 1990.

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Juan, Muscio Hernán, and López Gabriel E. J, eds. Theoretical and methodological issues in evolutionary archaeology: Toward an unified Darwinian paradigm = Questions théorétiques et méthodologiques en archéologie évolutive : vers un paradigme Darwinien unifié. Oxford, England: Archaeopress, 2009.

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Evolution and constitution: The evolutionary selfconstruction [i.e. self-construction] of law. Dordrecht: Kluwer Academic, 2003.

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International Congress of Prehistoric and Protohistoric Sciences (15th 2006 Lisbon, Portugal). Theoretical and methodological issues in evolutionary archaeology: Toward an unified Darwinian paradigm = Questions théorétiques et méthodologiques en archéologie évolutive : vers un paradigme Darwinien unifié. Oxford, England: Archaeopress, 2009.

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Handbook of comparative genomics: Principles and methodology. Hoboken, NJ: Wiley-Liss, 2002.

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Tuggle, Melvin. The evolution of John Dewey's conception of philosophy and his notion of truth. Lanham, MD: University Press of America, 1997.

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Trouwborst, Arie. Evolution and status of the precautionary principle on international law. The Hague, Netherlands: Kluwer Law International, 2002.

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Book chapters on the topic "Evolution – Methodology"

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Dori, Dov. "System Lifecycle and Evolution." In Object-Process Methodology, 289–309. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-642-56209-9_11.

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Oeser, Erhard. "Legal Philosophy as Methodology." In Evolution and Constitution, 29–84. Dordrecht: Springer Netherlands, 2003. http://dx.doi.org/10.1007/978-94-017-1502-7_2.

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Temovski, Marjan. "Methodology." In Evolution of Karst in the Lower Part of Crna Reka River Basin, 23–41. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-24547-8_3.

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Freedman, Rick. "Agile Evolution: More Than Methodology." In The Agile Consultant, 19–34. Berkeley, CA: Apress, 2016. http://dx.doi.org/10.1007/978-1-4302-6053-0_2.

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Repa, Vaclav. "Methodology for Business Processes Analysis." In Evolution and Challenges in System Development, 147–57. Boston, MA: Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4851-5_14.

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Haarmann, Alexander. "Methodology and Study Design." In The Evolution and Everyday Practice of Collective Patient Involvement in Europe, 55–72. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-64595-7_4.

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Kijas, Szymon, and Andrzej Zalewski. "Towards Evolution Methodology for Service-Oriented Systems." In New Results in Dependability and Computer Systems, 255–73. Heidelberg: Springer International Publishing, 2013. http://dx.doi.org/10.1007/978-3-319-00945-2_23.

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Tacconi Stefanelli, Carlo, Samuele Segoni, Nicola Casagli, and Filippo Catani. "Assessing Landslide Dams Evolution: A Methodology Review." In Advancing Culture of Living with Landslides, 253–57. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-53483-1_29.

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Yablokov, Alexey. "Contribution of N.W. Timoféeff-Ressovsky to Biology and Methodology of Science." In Genetics, Evolution and Radiation, 29–32. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-48838-7_3.

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Pan, Jiaofeng. "Evolution and Exploration of Think Tank Research Methods." In DIIS Theory and Methodology in Think Tanks, 21–32. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-0618-2_2.

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Conference papers on the topic "Evolution – Methodology"

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Jaziri, Wassim. "A Methodology for Ontology Evolution and Versioning." In 2009 Third International Conference on Advances in Semantic Processing (SEMAPRO). IEEE, 2009. http://dx.doi.org/10.1109/semapro.2009.22.

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Lim, Dongwook, and Dimitri Mavris. "A Design Methodology for Lifelong Aircraft Evolution." In 48th AIAA Aerospace Sciences Meeting Including the New Horizons Forum and Aerospace Exposition. Reston, Virigina: American Institute of Aeronautics and Astronautics, 2010. http://dx.doi.org/10.2514/6.2010-283.

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Leemans, Maikel, Wil M. P. van der Aalst, Mark G. J. van den Brand, Ramon R. H. Schiffelers, and Leonard Lensink. "Software Process Analysis Methodology – A Methodology Based on Lessons Learned in Embracing Legacy Software." In 2018 IEEE International Conference on Software Maintenance and Evolution (ICSME). IEEE, 2018. http://dx.doi.org/10.1109/icsme.2018.00076.

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Beckmann, Benjamin E., Laura M. Grabowski, Philip K. McKinley, and Charles Ofria. "Autonomic Software Development Methodology Based on Darwinian Evolution." In 2008 International Conference on Autonomic Computing (ICAC). IEEE, 2008. http://dx.doi.org/10.1109/icac.2008.19.

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Lakhal, Fadoi, Hubert Dubois, and Dominique Rieu. "Pattern based methodology for UML profiles evolution management." In 2013 IEEE Seventh International Conference on Research Challenges in Information Science (RCIS). IEEE, 2013. http://dx.doi.org/10.1109/rcis.2013.6577681.

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Lee, Yiu-Yin, and Heung-Fai Lam. "AN EVOLUTION STRATEGY BASED PROBABILISTIC MODEL UPDATING METHODOLOGY." In Proceedings of the Second International Conference. WORLD SCIENTIFIC, 2002. http://dx.doi.org/10.1142/9789812776228_0113.

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Wu, Yumei, and Yongli Yu. "The mission reliability modeling methodology for software dynamic evolution." In 2013 International Conference on Quality, Reliability, Risk, Maintenance, and Safety Engineering (QR2MSE). IEEE, 2013. http://dx.doi.org/10.1109/qr2mse.2013.6625599.

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Drechsler, Rolf, Christophe Chevallaz, Franco Fummi, Alan J. Hu, Ronny Morad, Frank Schirrmeister, and Alex Goryachev. "Panel: Future SoC verification methodology: UVM evolution or revolution?" In Design Automation and Test in Europe. New Jersey: IEEE Conference Publications, 2014. http://dx.doi.org/10.7873/date2014.385.

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Drechsler, Rolf, Christophe Chevallaz, Franco Fummi, Alan J. Hu, Ronny Morad, Frank Schirrmeister, and Alex Goryachev. "Panel: Future SoC verification methodology: UVM evolution or revolution?" In Design Automation and Test in Europe. New Jersey: IEEE Conference Publications, 2014. http://dx.doi.org/10.7873/date.2014.385.

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LYN, HEIDI. "COMPARATIVE PSYCHOLOGY AND THE EVOLUTION OF LANGUAGE: METHODOLOGY MATTERS." In EVOLANG 10. WORLD SCIENTIFIC, 2014. http://dx.doi.org/10.1142/9789814603638_0104.

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Reports on the topic "Evolution – Methodology"

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T.L. Mitchell. Design Evolution Study Thermal Operating Methodology. Office of Scientific and Technical Information (OSTI), April 2002. http://dx.doi.org/10.2172/899932.

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Flici, Farid, and Nacer-Eddine Hammouda. Mortality evolution in Algeria: What can we learn about data quality? Verlag der Österreichischen Akademie der Wissenschaften, August 2021. http://dx.doi.org/10.1553/populationyearbook2021.res1.3.

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Mortality in Algeria has declined significantly since the country declared its independence in 1962. This trend has been accompanied by improvements in data quality and changes in estimation methodology, both of which are scarcely documented, and may distort the natural evolution of mortality as reported in official statistics. In this paper, our aim is to detect these methodological and data quality changes by means of the visual inspection of mortality surfaces, which represent the evolution of mortality rates, mortality improvement rates and the male-female mortality ratio over age and time. Data quality problems are clearly visible during the 1977–1982 period. The quality of mortality data has improved after 1983, and even further since the population census of 1998, which coincided with the end of the civil war. Additional inexplicable patterns have also been detected, such as a changing mortality age pattern during the period before 1983, and a changing pattern of excess female mortality at reproductive ages, which suddenly appears in 1983 and disappears in 1992.
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Gamba-Santamaria, Santiago, Luis Fernando Melo-Velandia, and Camilo Orozco-Vanegas. What can credit vintages tell us about non-performing loans? Banco de la República de Colombia, February 2021. http://dx.doi.org/10.32468/be.1154.

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Using Colombian credit vintage data, we decompose the non-performing loans into one component that captures the evolution of the payment capacity of borrowers, and other component that captures changes in the credit risk taken by the financial system at the time of loan disbursement. We use intrinsic estimators and penalized regression techniques to overcome the perfect multicollinearity problem that the model entails. We find that these two type of components have evolved differently over time, and that good economic conditions and loose financial conditions improve the payment capacity of borrowers to meet their obligations, and in turn, they tend to coincide with the financial system engaging in riskier loans. Finally, we advocate the use of this methodology as a policy tool that is easy to apply by financial and economic authorities that dispose of a constant flow of credit vintage information. Through it, they will be able to identify the origin of the credit risk materialization and curb the risk taken by the financial system.
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Roye, Thorsten. Unsettled Technology Areas in Deterministic Assembly Approaches for Industry 4.0. SAE International, August 2021. http://dx.doi.org/10.4271/epr2021018.

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Increased production rates and cost reduction are affecting manufacturing in all sectors of the mobility industry. One enabling methodology that could achieve these goals in the burgeoning “Industry 4.0” environment is the deterministic assembly (DA) approach. The DA approach is defined as an optimized assembly process; it always forms the same final structure and has a strong link to design-for-assembly and design-for-automation methodologies. It also looks at the whole supply chain, enabling drastic savings at the original equipment manufacturer (OEM) level by reducing recurring costs and lead time. Within Industry 4.0, DA will be required mainly for the aerospace and the space industry, but serves as an interesting approach for other industries assembling large and/or complex components. In its entirety, the DA approach connects an entire supply chain—from part manufacturing at an elementary level to an OEM’s final assembly line level. Addressing the whole process of aircraft design and manufacturing is necessary to develop further collaboration models between OEMs and the supply chain, including addressing the most pressing technology challenges. Since all parts aggregate at the OEM level, the OEM—as an integrator of all these single parts—needs special end-to-end methodologies to drastically decrease cost and lead time. This holistic approach can be considered in part design as well (in the design-for-automation and design-for-assembly philosophy). This allows for quicker assembly at the OEM level, such as “part-to-part” or “hole-to-hole” approaches, versus traditional, classical assembly methods like manual measurement or measurement-assisted assembly. In addition, it can increase flexibility regarding rate changes in production (such as those due to pandemic- or climate-related environmental challenges). The standardization and harmonization of these areas would help all industries and designers to have a deterministic approach with an end-to-end concept. Simulations can easily compare possible production and assembly steps with different impacts on local and global tolerances. Global measurement feedback needs high-accuracy turnkey solutions, which are very costly and inflexible. The goal of standardization would be to use Industry 4.0 feedback and features, as well as to define several building blocks of the DA approach as a one-way assembly (also known as one-up assembly, or “OUA”), false one-way assembly, “Jig-as-Master,” etc., up to the hole-to-hole assembly approach. The evolution of these assembly principles and the link to simulation approaches are undefined and unsolved domains; they are discussed in this report. They must be discussed in greater depth with aims of (first) clarifying the scope of the industry-wide alignment needs and (second) prioritizing the issues requiring standardization. NOTE: SAE EDGE™ Research Reports are intended to identify and illuminate key issues in emerging, but still unsettled, technologies of interest to the mobility industry. The goal of SAE EDGE™ Research Reports is to stimulate discussion and work in the hope of promoting and speeding resolution of identified issues. SAE EDGE™ Research Reports are not intended to resolve the challenges they identify or close any topic to further scrutiny.
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National report 2009-2019 - Rural NEET in Romania. OST Action CA 18213: Rural NEET Youth Network: Modeling the risks underlying rural NEETs social exclusion, December 2020. http://dx.doi.org/10.15847/cisrnyn.nrro.2020.12.

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This report describes a particular situation of young population in Romania: the population of NEETs, with a focus on rural NEETs.Based on a complex methodology which uses data from different national sources (INS) and international sources (Eurostat, EU Labour Force Survey-EU-LFS, OECD),this report gives an overview of the evolution and particularities of NEETs in Romania during the previous deca-de, namely 2009-2019.Within the last ten years, the population of NEETs in Romania has grown rapidly, placing Ro-mania in first place in the EU-28 in terms of the share of this population among the young population. Thus, in 2009 Romania with a NEET rate of 13.9%, occupied first places in the EU, along with Bulgaria (19.5%), Italy (17.5%), Latvia (17.5%) (Eurostat, 2020). A decade later, in Bulgaria and Latvia, the NEET rate decreased significantly to 13.7% and 7.9%, respectively, but in Romania and Italy it increased by more than 1pp: 14.7% in Romania and 18.1% in Italy. (Eurostat, 2020). The causes for this are both individual (way of life, socio-familial origin, expectations and aspirations) and socio-economic (accessibility of the education system, development of lifelong learning, correspondence between education and labour market demand, particu-larities of the Romanian labour market, socio-economic policies supported by central and local authorities, etc.)
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Payment Systems Report - June of 2020. Banco de la República de Colombia, February 2021. http://dx.doi.org/10.32468/rept-sist-pag.eng.2020.

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With its annual Payment Systems Report, Banco de la República offers a complete overview of the infrastructure of Colombia’s financial market. Each edition of the report has four objectives: 1) to publicize a consolidated account of how the figures for payment infrastructures have evolved with respect to both financial assets and goods and services; 2) to summarize the issues that are being debated internationally and are of interest to the industry that provides payment clearing and settlement services; 3) to offer the public an explanation of the ideas and concepts behind retail-value payment processes and the trends in retail payments within the circuit of individuals and companies; and 4) to familiarize the public, the industry, and all other financial authorities with the methodological progress that has been achieved through applied research to analyze the stability of payment systems. This edition introduces changes that have been made in the structure of the report, which are intended to make it easier and more enjoyable to read. The initial sections in this edition, which is the eleventh, contain an analysis of the statistics on the evolution and performance of financial market infrastructures. These are understood as multilateral systems wherein the participating entities clear, settle and register payments, securities, derivatives and other financial assets. The large-value payment system (CUD) saw less momentum in 2019 than it did the year before, mainly because of a decline in the amount of secondary market operations for government bonds, both in cash and sell/buy-backs, which was offset by an increase in operations with collective investment funds (CIFs) and Banco de la República’s operations to increase the money supply (repos). Consequently, the Central Securities Depository (DCV) registered less activity, due to fewer negotiations on the secondary market for public debt. This trend was also observed in the private debt market, as evidenced by the decline in the average amounts cleared and settled through the Central Securities Depository of Colombia (Deceval) and in the value of operations with financial derivatives cleared and settled through the Central Counterparty of Colombia (CRCC). Section three offers a comprehensive look at the market for retail-value payments; that is, transactions made by individuals and companies. During 2019, electronic transfers increased, and payments made with debit and credit cards continued to trend upward. In contrast, payments by check continued to decline, although the average daily value was almost four times the value of debit and credit card purchases. The same section contains the results of the fourth survey on how the use of retail-value payment instruments (for usual payments) is perceived. Conducted at the end of 2019, the main purpose of the survey was to identify the availability of these payment instruments, the public’s preferences for them, and their acceptance by merchants. It is worth noting that cash continues to be the instrument most used by the population for usual monthly payments (88.1% with respect to the number of payments and 87.4% in value). However, its use in terms of value has declined, having registered 89.6% in the 2017 survey. In turn, the level of acceptance by merchants of payment instruments other than cash is 14.1% for debit cards, 13.4% for credit cards, 8.2% for electronic transfers of funds and 1.8% for checks. The main reason for the use of cash is the absence of point-of-sale terminals at commercial establishments. Considering that the retail-payment market worldwide is influenced by constant innovation in payment services, by the modernization of clearing and settlement systems, and by the efforts of regulators to redefine the payment industry for the future, these trends are addressed in the fourth section of the report. There is an account of how innovations in technology-based financial payment services have developed, and it shows that while this topic is not new, it has evolved, particularly in terms of origin and vocation. One of the boxes that accompanies the fourth section deals with certain payment aspects of open banking and international experience in that regard, which has given the customers of a financial entity sovereignty over their data, allowing them, under transparent and secure conditions, to authorize a third party, other than their financial entity, to request information on their accounts with financial entities, thus enabling the third party to offer various financial services or initiate payments. Innovation also has sparked interest among international organizations, central banks, and research groups concerning the creation of digital currencies. Accordingly, the last box deals with the recent international debate on issuance of central bank digital currencies. In terms of the methodological progress that has been made, it is important to underscore the work that has been done on the role of central counterparties (CCPs) in mitigating liquidity and counterparty risk. The fifth section of the report offers an explanation of a document in which the work of CCPs in financial markets is analyzed and corroborated through an exercise that was built around the Central Counterparty of Colombia (CRCC) in the Colombian market for non-delivery peso-dollar forward exchange transactions, using the methodology of network topology. The results provide empirical support for the different theoretical models developed to study the effect of CCPs on financial markets. Finally, the results of research using artificial intelligence with information from the large-value payment system are presented. Based on the payments made among financial institutions in the large-value payment system, a methodology is used to compare different payment networks, as well as to determine which ones can be considered abnormal. The methodology shows signs that indicate when a network moves away from its historical trend, so it can be studied and monitored. A methodology similar to the one applied to classify images is used to make this comparison, the idea being to extract the main characteristics of the networks and use them as a parameter for comparison. Juan José Echavarría Governor
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