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Journal articles on the topic 'Exact sequences. eng'

Author: Grafiati

Published: 4 June 2021

Last updated: 5 February 2022

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1

LÜ, JIA-FENG, and MIAO-SEN CHEN. "ON A SPECIAL CLASS OF EXACT SEQUENCES." Journal of Algebra and Its Applications 10, no. 05 (2011): 915–30. http://dx.doi.org/10.1142/s021949881100504x.

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The notion of good exact sequence is introduced, which is a special class of exact sequences including split exact sequences as special examples. Several criteria characterizing good exact sequences are given. In particular, we prove that the exact sequence ξ: 0 → K → M → N → 0 is good if and only if the Horseshoe Lemma is true in the "minimal version" with respect to ξ. We also give a lot of nontrivial examples of good exact sequences via "Koszul" objects. Moreover, some applications of good exact sequences are also provided in the end.

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Bennis, Driss, J. R. García Rozas, Lixin Mao, and Luis Oyonarte. "On Proper and Exact Relative Homological Dimensions." Algebra Colloquium 27, no. 03 (2020): 621–42. http://dx.doi.org/10.1142/s1005386720000516.

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In Enochs’ relative homological dimension theory occur the (co)resolvent and (co)proper dimensions, which are defined by proper and coproper resolutions constructed by precovers and preenvelopes, respectively. Recently, some authors have been interested in relative homological dimensions defined by just exact sequences. In this paper, we contribute to the investigation of these relative homological dimensions. First we study the relation between these two kinds of relative homological dimensions and establish some transfer results under adjoint pairs. Then relative global dimensions are studie

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Hernandez, L. J., and T. Porter. "Global analogues of the Brown–Grossman proper homotopy groups of an end." Mathematical Proceedings of the Cambridge Philosophical Society 104, no. 3 (1988): 483–96. http://dx.doi.org/10.1017/s0305004100065671.

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AbstractThe Brown–Grossman proper homotopy groups at an end of a locally compact Hausdorff space, X, were introduced by E. M. Brown in 1974. In this note we define and study ‘global’ versions of these groups and compare these global groups with the groups ‘at infinity’. We also obtain several interlocking exact sequences relating these groups with the Hurewicz and Steenrod homotopy groups of X.

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HUNG, CHIN-YI, ZICONG ZHOU, YUAN-SHIN YOUNG, and FANG-TING LIN. "EVALUATING MEAN INTRINSIC CURVATURE OF DISORDERED SEMIFLEXIBLE BIOPOLYMERS." International Journal of Modern Physics B 26, no. 24 (2012): 1250131. http://dx.doi.org/10.1142/s0217979212501317.

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We study two-dimensional disordered semiflexible biopolymers with finite mean intrinsic curvature (MIC). We find exact distribution function of orientational angle for the system with short-range correlation (SRC) in intrinsic curvatures. We show that with a finite MIC, our theoretical end-to-end distances can be fitted well to some experimental data of DNA with long-range correlation (LRC) in sequences. Moreover, we find that the variance of the orientational angle has the same power-law behavior as that of the bending profile for DNA with LRC in sequences. Our results provide a way to evalua

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PROSPERI, MATTIA C. F., LUCIANO PROSPERI, REBECCA R. GRAY, and MARCO SALEMI. "ON COUNTING THE FREQUENCY DISTRIBUTION OF STRING MOTIFS IN MOLECULAR SEQUENCES." International Journal of Biomathematics 05, no. 06 (2012): 1250055. http://dx.doi.org/10.1142/s1793524512500556.

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This work investigates frequency distributions of strings within a text. The mathematical derivation accounts for variable alphabet size, character probabilities, and string/text lengths, under both the Bernoullian and the Markovian model for string generation. The analysis is limited to the set of non-clumpable strings, that cannot overlap with themselves. Two formulae (exact and approximated) are derived, calculating the frequency distribution of a string of length m found inside a text of length n (with m < n). The approximated formula has a constant complexity (in contrast to an exponen

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Cooke, Howard J. "Telomeres of the human X and Y chromosomes." Development 101, Supplement (1987): 101–6. http://dx.doi.org/10.1242/dev.101.supplement.101.

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Analysis of the nature of the DNA sequences at the telomeres of the short arms of the human sex chromosomes suggests parallels with the structures found at telomeres of a number of lower eukaryotes. The exact nature of the end of the DNA has not yet been established but it is clear that there are multiple levels of variability both between and within individuals in this region of the genome.

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Lamppa, G. K., G. Morelli, and N. H. Chua. "Structure and developmental regulation of a wheat gene encoding the major chlorophyll a/b-binding polypeptide." Molecular and Cellular Biology 5, no. 6 (1985): 1370–78. http://dx.doi.org/10.1128/mcb.5.6.1370.

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A genomic clone for a major chlorophyll a/b-binding polypeptide of the light-harvesting complex has been sequenced from wheat. This gene, whAB1.6, encodes a 70-nucleotide 5'-nontranslated spacer, a 34-amino-acid NH2-terminal extension, i.e., the transit peptide, and a mature coding protein of 232 amino acid residues. The exact molecular weight of the precursor polypeptide is 28,560. The transit peptide is basic and is rich in serines. No intervening sequences are found in this gene. The transcription start site of the whAB1.6 gene occurs at AAAC as determined by S1 nuclease analysis. Putative

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Lamppa, G. K., G. Morelli, and N. H. Chua. "Structure and developmental regulation of a wheat gene encoding the major chlorophyll a/b-binding polypeptide." Molecular and Cellular Biology 5, no. 6 (1985): 1370–78. http://dx.doi.org/10.1128/mcb.5.6.1370-1378.1985.

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A genomic clone for a major chlorophyll a/b-binding polypeptide of the light-harvesting complex has been sequenced from wheat. This gene, whAB1.6, encodes a 70-nucleotide 5'-nontranslated spacer, a 34-amino-acid NH2-terminal extension, i.e., the transit peptide, and a mature coding protein of 232 amino acid residues. The exact molecular weight of the precursor polypeptide is 28,560. The transit peptide is basic and is rich in serines. No intervening sequences are found in this gene. The transcription start site of the whAB1.6 gene occurs at AAAC as determined by S1 nuclease analysis. Putative

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9

Newcombe, H. B., M. E. Fair, and P. Lalonde. "Discriminating Powers of Partial Agreements of Names for Linking Personal Records." Methods of Information in Medicine 28, no. 02 (1989): 92–96. http://dx.doi.org/10.1055/s-0038-1635548.

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Abstract:The preceeding paper examined the logical basis of an exact way of calculating the discriminating powers of people’s names when they only partially agree. The method has application to automated file searching and record linkage. The present account describes an empirical test of the approach. Use is made of some 2000 comparison pairs of male given names, obtained as a byproduct from an earlier linkage study. The test shows that exact value-specific ODDS can indeed be calculated for common names when compared with their accepted synonyms (e.g. JOSEPH versus JOE). Moreover, the use can

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Nandor, M. J. "Delving Deeper: Simple Recurrence Relations, Proper Guessing, and Closed-Form Solutions." Mathematics Teacher 99, no. 4 (2005): 292–95. http://dx.doi.org/10.5951/mt.99.4.0292.

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In reading the February 2004 issue of the Mathematics Teacher, I found the wonderful “Delving Deeper” article “Fibonacci and Related Sequences,” by Richard Askey. At the end, in the editors' note, the question was posed whether Fibonacci numbers can be found in a closed form. As it happened, I was teaching that exact topic in my discrete mathematics class at the time. Ever since taking discrete mathematics in college, recurrence relations have fascinated me, and the derivation of a functional form of the Fibonacci sequence is just one great example of how recurrence relations can be used, even

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Neri, Paola, Ranjan Maity, Sylvia McCulloch, et al. "Identification of Specificity Groups in Myeloma Patients T Cell Receptor (TCR) Repertoire through Single Cell TCR Sequencing." Blood 132, Supplement 1 (2018): 4459. http://dx.doi.org/10.1182/blood-2018-99-117482.

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Abstract Background: A renewed interest in immune and cellular based therapeutics in multiple myeloma was recently fueled by the development of CD38 targeting monoclonal antibodies as well as the introduction of engineered CAR-T cells. Daratumumab treatment in myeloma patients was demonstrated to expand clonal CD8+T cells and T cell clonality was correlated with the depth of response consistent with a daratumumab mediated cytotoxic T cell effect. However the mechanisms behind this adaptive immune response and the identity of the T cell receptor (TCR) interacting with MHC presented tumoral pept

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Sultan, Ibrahim, Vincent Fromion, Sophie Schbath, and Pierre Nicolas. "Statistical modelling of bacterial promoter sequences for regulatory motif discovery with the help of transcriptome data: application to Listeria monocytogenes." Journal of The Royal Society Interface 17, no. 171 (2020): 20200600. http://dx.doi.org/10.1098/rsif.2020.0600.

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Automatic de novo identification of the main regulons of a bacterium from genome and transcriptome data remains a challenge. To address this task, we propose a statistical model that can use information on exact positions of the transcription start sites and condition-dependent expression profiles. The central idea of this model is to improve the probabilistic representation of the promoter DNA sequences by incorporating covariates summarizing expression profiles (e.g. coordinates in projection spaces or hierarchical clustering trees). A dedicated trans-dimensional Markov chain Monte Carlo alg

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NEHANIV, CHRYSTOPHER LEV. "ALGEBRAIC CONNECTIVITY." International Journal of Algebra and Computation 01, no. 04 (1991): 445–71. http://dx.doi.org/10.1142/s0218196791000316.

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Let [Formula: see text] be a type of algebra in the sense of universal algebra. By defining singular simplices in algebras and emulating singular [co] homology, we introduce for each variety, pseudo-variety, and divisional class V of type [Formula: see text], a homology and cohomology theory which measure the V-connectivity of type-[Formula: see text] algebras. Intuitively, if we were to think of an algebra as a space and subalgebras which lie in V as simplices, then V-connectivity describes the failure of subalgebras to lie in V, i.e., it describes the "holes" in this space. These [co]homolog

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Bart, Victoria KE, Iring Koch, and Martina Rieger. "Decay of inhibition in motor imagery." Quarterly Journal of Experimental Psychology 74, no. 1 (2020): 77–94. http://dx.doi.org/10.1177/1747021820949388.

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During motor imagery, global inhibition and effector-specific inhibition contribute to prevent actual movements. We investigated the decay of inhibition using an action-mode switching paradigm. Participants switched between imagined and executed hand movements. Response–stimulus intervals (RSIs) were varied (200, 700, 1,300, and 2,000 ms). As inhibition (due to imagination) or activation (due to execution) in one trial affects performance in the subsequent trial, we analysed sequential effects. Evidence for the contribution of global inhibition (e.g., switch benefits in execution [E]—imaginati

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Reingruber, Agathe, and Laurens Thissen. "Depending on 14C Data: Chronological Frameworks in the Neolithic and Chalcolithic of Southeastern Europe." Radiocarbon 51, no. 2 (2009): 751–70. http://dx.doi.org/10.1017/s0033822200056071.

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With the introduction of the radiocarbon method in 1949 and the calibration curve constantly improving since 1965, but especially due to the development of the more accurate accelerator mass spectrometry (AMS) dating some 30 yr ago, the application of the 14C method in prehistory revolutionized traditional chronological frameworks. Theories and models are adjusted to new 14C sequences, and such sequences even lead to the creation of new theories and models. In our contribution, we refer to 2 major issues that are still heavily debated, although their first absolute dating occurred some decades

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Pragarauskaitė, Julija, and Gintautas Dzemyda. "Tikimybinis dažnų posekių paieškos algoritmas." Informacijos mokslai 50 (January 1, 2009): 352–57. http://dx.doi.org/10.15388/im.2009.0.3211.

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Dažnų posekių paieška didelėse duomenų bazėse yra svarbi biologinių, klimato, fi nansinių ir daugelio kitų duomenų bazių analizei. Tikslieji algoritmai, skirti dažnų posekių paieškai, daug kartų perrenka visą duomenų bazę. Jeigu duomenų bazė didelė, tai dažnų posekių paieška yra lėta arba reikalingi superkompiuteriai. Straipsnyje pasiūlytas naujas tikimybinis dažnų posekių paieškos algoritmas, kuris analizuoja tam tikru būdu sudarytą pradinės duomenų bazės atsitiktinę imtį. Remiantis šia analizedaromos statistinės išvados apie dažnus posekius pradinėje duomenų bazėje. Šis algoritmas nėra tiksl

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Amir, E., and A. Chang. "Learning Partially Observable Deterministic Action Models." Journal of Artificial Intelligence Research 33 (November 20, 2008): 349–402. http://dx.doi.org/10.1613/jair.2575.

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We present exact algorithms for identifying deterministic-actions' effects and preconditions in dynamic partially observable domains. They apply when one does not know the action model(the way actions affect the world) of a domain and must learn it from partial observations over time. Such scenarios are common in real world applications. They are challenging for AI tasks because traditional domain structures that underly tractability (e.g., conditional independence) fail there (e.g., world features become correlated). Our work departs from traditional assumptions about partial observations and

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Hoppe, Katharina, Edmund Wascher, and Kristina Küper. "Feature Overlap and Relevance Determine Sequential Modulations in the Simon Task." Journal of Psychophysiology 34, no. 2 (2020): 81–98. http://dx.doi.org/10.1027/0269-8803/a000239.

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Abstract. Subjects usually respond faster and more accurate in trials in which the response location corresponds to a task-irrelevant stimulus location compared to when not. Previous research has shown, that this so-called Simon effect is reduced after non-corresponding compared to after corresponding trials. As of now it is yet unclear what exact mechanisms drive such sequential modulations. One theory assumes a conflict adaptation mechanism that decreases the influence of incongruent information after non-corresponding trials via increased cognitive control. However, other authors claim that

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19

Berend, Daniel, Shlomi Dolev, and Ariel Hanemann. "Graph Degree Sequence Solely Determines the Expected Hopfield Network Pattern Stability." Neural Computation 27, no. 1 (2015): 202–10. http://dx.doi.org/10.1162/neco_a_00685.

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We analyze the effect of network topology on the pattern stability of the Hopfield neural network in the case of general graphs. The patterns are randomly selected from a uniform distribution. We start the Hopfield procedure from some pattern v. An error in an entry e of v is the situation where, if the procedure is started at e, the value of e flips. Such an entry is an instability point. Note that we disregard the value at e by the end of the procedure, as well as what happens if we start the procedure from another pattern [Formula: see text] or another entry [Formula: see text] of v. We mea

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Pleschka, Stephan, Peter Staeheli, Jolanta Kolodziejek, Jürgen A. Richt, Norbert Nowotny, and Martin Schwemmle. "Conservation of coding potential and terminal sequences in four different isolates of Borna disease virus." Journal of General Virology 82, no. 11 (2001): 2681–90. http://dx.doi.org/10.1099/0022-1317-82-11-2681.

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We determined the complete nucleotide sequences of two poorly characterized strains of Borna disease virus (BDV) and compared them to reference strains V and He/80. Strain H1766 was almost 98% and 95% identical to strains V and He/80, respectively, whereas strain No/98 was only about 81% identical to both reference strains. In contrast to earlier reports, we found an additional A residue at the extreme 3′-end of the single-stranded RNA genome in all four BDV strains. The exact numbers of nucleotides in the four BDV genomes could not be determined due to a micro-heterogeneity at the 5′-end. If

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LIANG, SENLIN, and MICHAEL KIFER. "A practical analysis of non-termination in large logic programs." Theory and Practice of Logic Programming 13, no. 4-5 (2013): 705–19. http://dx.doi.org/10.1017/s1471068413000446.

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AbstractA large body of work has been dedicated to termination analysis of logic programs but relatively little has been done to analyze non-termination. In our opinion, explaining non-termination is a much more important task because it can dramatically improve a user's ability to effectively debug large, complex logic programs without having to abide by punishing syntactic restrictions. Non-termination analysis examines program execution history when the program is suspected to not terminate and informs the programmer about the exact reasons for this behavior. In Liang and Kifer (2013), we s

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Field, L. M., M. S. Williamson, G. D. Moores, and A. L. Devonshire. "Cloning and analysis of the esterase genes conferring insecticide resistance in the peach-potato aphid, Myzus persicae (Sulzer)." Biochemical Journal 294, no. 2 (1993): 569–74. http://dx.doi.org/10.1042/bj2940569.

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Full-length cDNA clones encoding the esterases (E4 and FE4) that confer insecticide resistance in the peach-potato aphid [Myzus persicae (Sulzer)] were isolated and characterized. The E4 cDNA contained an open reading frame of 1656 nucleotides, coding for a protein of 552 amino acids. The FE4 cDNA shared 99% identity with E4 over this region, the most important difference being a single nucleotide substitution resulting in the FE4 mRNA having an extra 36 nucleotides at the 3′ end. The derived amino acid sequences for the N-terminus of E4 and FE4 were identical, with the first 23 residues being

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Kaminiarz, Andre, Kerstin Königs, and Frank Bremmer. "The Main Sequence of Human Optokinetic Afternystagmus (OKAN)." Journal of Neurophysiology 101, no. 6 (2009): 2889–97. http://dx.doi.org/10.1152/jn.00114.2009.

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Different types of fast eye movements, including saccades and fast phases of optokinetic nystagmus (OKN) and optokinetic afternystagmus (OKAN), are coded by only partially overlapping neural networks. This is a likely cause for the differences that have been reported for the dynamic parameters of fast eye movements. The dependence of two of these parameters—peak velocity and duration—on saccadic amplitude has been termed “main sequence.” The main sequence of OKAN fast phases has not yet been analyzed. These eye movements are unique in that they are generated by purely subcortical control mecha

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Cummins, C. M., M. R. Culbertson, and G. Knapp. "Frameshift suppressor mutations outside the anticodon in yeast proline tRNAs containing an intervening sequence." Molecular and Cellular Biology 5, no. 7 (1985): 1760–71. http://dx.doi.org/10.1128/mcb.5.7.1760.

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Extragenic suppressors of +1 frameshift mutations in proline codons map in genes encoding two major proline tRNA isoacceptors. We have shown previously that one isoacceptor encoded by the SUF2 gene (chromosome 3) contains no intervening sequence. SUF2 suppressor mutations result from the base insertion of a G within a 3'-GGA-5' anticodon, allowing the tRNA to read a 4-base code word. In this communication we describe suppressor mutations in genes encoding a second proline tRNA isoacceptor (wild-type anticodon 3'-GGU-5') that result in a novel mechanism for translation of a 4-base genetic code

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Cummins, C. M., M. R. Culbertson, and G. Knapp. "Frameshift suppressor mutations outside the anticodon in yeast proline tRNAs containing an intervening sequence." Molecular and Cellular Biology 5, no. 7 (1985): 1760–71. http://dx.doi.org/10.1128/mcb.5.7.1760-1771.1985.

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Extragenic suppressors of +1 frameshift mutations in proline codons map in genes encoding two major proline tRNA isoacceptors. We have shown previously that one isoacceptor encoded by the SUF2 gene (chromosome 3) contains no intervening sequence. SUF2 suppressor mutations result from the base insertion of a G within a 3'-GGA-5' anticodon, allowing the tRNA to read a 4-base code word. In this communication we describe suppressor mutations in genes encoding a second proline tRNA isoacceptor (wild-type anticodon 3'-GGU-5') that result in a novel mechanism for translation of a 4-base genetic code

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Rognes, Torbjørn, Tomáš Flouri, Ben Nichols, Christopher Quince, and Frédéric Mahé. "VSEARCH: a versatile open source tool for metagenomics." PeerJ 4 (October 18, 2016): e2584. http://dx.doi.org/10.7717/peerj.2584.

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BackgroundVSEARCH is an open source and free of charge multithreaded 64-bit tool for processing and preparing metagenomics, genomics and population genomics nucleotide sequence data. It is designed as an alternative to the widely used USEARCH tool (Edgar, 2010) for which the source code is not publicly available, algorithm details are only rudimentarily described, and only a memory-confined 32-bit version is freely available for academic use.MethodsWhen searching nucleotide sequences, VSEARCH uses a fast heuristic based on words shared by the query and target sequences in order to quickly iden

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Iervolino, Iunio. "Generalized Earthquake Counting Processes for Sequence‐Based Hazard." Bulletin of the Seismological Society of America 109, no. 4 (2019): 1435–50. http://dx.doi.org/10.1785/0120180271.

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Abstract Sequence‐based probabilistic seismic hazard analysis (SPSHA) allows us to account for the effect of aftershocks in the assessment of seismic structural‐design actions (Iervolino et al., 2014, 2018). In fact, it generalizes classical probabilistic seismic hazard analysis (PSHA; Cornell, 1968), combining it with aftershock‐PSHA (Yeo and Cornell, 2009). SPSHA associates in time aftershocks to mainshocks and, therefore, retains a desirable property of classical PSHA; that is, events (earthquakes in PSHA and mainshock–aftershock sequences in SPSHA) occur according to homogeneous Poisson pr

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Korte, S., G. Springer, W. Spollen, et al. "254 DIFFERENTIAL TRANSCRIPTION AND CYSTOPLASMIC POLYADENYLATION ELEMENTS IN PORCINE GERMINAL VESICLE AND METAPHASE II OOCYTES." Reproduction, Fertility and Development 18, no. 2 (2006): 234. http://dx.doi.org/10.1071/rdv18n2ab254.

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Identification of transcripts produced during porcine oocyte maturation is one of the first steps in defining pathways important to development. Practically, this information will aid in the refinement of in vitro culture processes, allowing for more efficient in vitro embryo production. To this end, mRNA was isolated from 50 in vitro-matured sow metaphase II stage oocytes (Bomed, Inc., Madison, WI, USA) (MIIs), 50 in vitro-matured gilt metaphase II-stage oocytes (MIIg), and 50 gilt germinal vesicle stage oocytes (GVO) by using the Dynabead® system (Dynal, Inc., Lake Success, NY, USA) and ampl

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Marek, L. Fredrick, and R. C. Shoemaker. "BAC contig development by fingerprint analysis in soybean." Genome 40, no. 4 (1997): 420–27. http://dx.doi.org/10.1139/g97-056.

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We constructed a soybean bacterial artificial chromosome (BAC) library suitable for map-based cloning and physical mapping in soybean. This library consists of approximately 40 000 clones (4–5 genome equivalents) stored individually in 384-well microtiter dishes. A random sampling of 224 clones yielded an average insert size of 150 kb, giving a 98% probability of recovering any specific sequence. We screened the library for seven single or very low copy genie or genomic sequences using the polymerase chain reaction (PCR) and found between one and seven BACs for each of the seven sequences. Whe

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Huertas-Company, Marc, Vicente Rodriguez-Gomez, Dylan Nelson, et al. "The Hubble Sequence at z ∼ 0 in the IllustrisTNG simulation with deep learning." Monthly Notices of the Royal Astronomical Society 489, no. 2 (2019): 1859–79. http://dx.doi.org/10.1093/mnras/stz2191.

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ABSTRACT We analyse the optical morphologies of galaxies in the IllustrisTNG simulation at z ∼ 0 with a convolutional neural network trained on visual morphologies in the Sloan Digital Sky Survey. We generate mock SDSS images of a mass complete sample of $\sim 12\, 000$ galaxies in the simulation using the radiative transfer code SKIRT and include PSF and noise to match the SDSS r-band properties. The images are then processed through the exact same neural network used to estimate SDSS morphologies to classify simulated galaxies in four morphological classes (E, S0/a, Sab, Scd). The CNN model

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Krell, Pina Fanny Ida, Stephan Weber, Susanne Reuther, et al. "Next Generation Sequencing Spectratyping (NGS-S) Comprehensively Monitors T Cell Receptor Diversity in Children with T Cell Abnormalities." Blood 118, no. 21 (2011): 2173. http://dx.doi.org/10.1182/blood.v118.21.2173.2173.

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Abstract Abstract 2173 The adaptive arm of the immune system - the T-cell compartment – may become compromised by inherited or acquired defects resulting in cancer, autoimmunity, or increased susceptibility to microbial infectious agents. A normal polyclonal T cell compartment comprises an estimated number of 2.5 × 10E7 individual T cell clones each expressing a unique antigen recognizing T cell receptor (TCR). The functionality of the T cell compartment is thus – at least partly - reflected by TCR sequence diversity. There is a medical need for rapid and robust diagnostic approaches that accu

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Tilney, L. G., and S. Inoué. "Acrosomal reaction of the Thyone sperm. III. The relationship between actin assembly and water influx during the extension of the acrosomal process." Journal of Cell Biology 100, no. 4 (1985): 1273–83. http://dx.doi.org/10.1083/jcb.100.4.1273.

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In an attempt to investigate the role of water influx in the extension of the acrosomal process of Thyone sperm, we induced the acrosomal reaction in sea water whose osmolarity varied from 50 to 150% of that of sea water. (a) Video sequences of the elongation of the acrosomal processes were made; plots of the length of the acrosomal process as a function of (time)1/2 produced a straight line except at the beginning of elongation and at the end in both hypotonic and hypertonic sea water (up to 1.33 times the osmolarity of sea water), although the rate of elongation was fastest in hypotonic sea

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Hu, Zhaohua, and Xiaoyi Shi. "Deep Directional Network for Object Tracking." Algorithms 11, no. 11 (2018): 178. http://dx.doi.org/10.3390/a11110178.

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Existing object trackers are mostly based on correlation filtering and neural network frameworks. Correlation filtering is fast but has poor accuracy. Although a neural network can achieve high precision, a large amount of computation increases the tracking time. To address this problem, we utilize a convolutional neural network (CNN) to learn object direction. We propose a target direction classification network based on CNNs that has a directional shortcut to the tracking target, unlike the particle filter that randomly finds the target. Our network uses an end-to-end approach to determine s

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Moraczewska, Joanna. "Structural determinants of cooperativity in acto-myosin interactions." Acta Biochimica Polonica 49, no. 4 (2002): 805–12. http://dx.doi.org/10.18388/abp.2002_3740.

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Regulation of muscle contraction is a very cooperative process. The presence of tropomyosin on the thin filament is both necessary and sufficient for cooperativity to occur. Data recently obtained with various tropomyosin isoforms and mutants help us to understand better the structural requirements in the thin filament for cooperative protein interactions. Forming an end-to-end overlap between neighboring tropomyosin molecules is not necessary for the cooperativity of the thin filament activation. When direct contacts between tropomyosin molecules are disrupted, the conformational changes in t

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Hoyos-Nogués, Mireia, Elena Falgueras-Batlle, Maria-Pau Ginebra, José Manero, Javier Gil, and Carlos Mas-Moruno. "A Dual Molecular Biointerface Combining RGD and KRSR Sequences Improves Osteoblastic Functions by Synergizing Integrin and Cell-Membrane Proteoglycan Binding." International Journal of Molecular Sciences 20, no. 6 (2019): 1429. http://dx.doi.org/10.3390/ijms20061429.

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Synergizing integrin and cell-membrane heparan sulfate proteoglycan signaling on biomaterials through peptidic sequences is known to have beneficial effects in the attachment and behavior of osteoblasts; however, controlling the exact amount and ratio of peptides tethered on a surface is challenging. Here, we present a dual molecular-based biointerface combining integrin (RGD) and heparin (KRSR)-binding peptides in a chemically controlled fashion. To this end, a tailor-made synthetic platform (PLATF) was designed and synthesized by solid-phase methodologies. The PLATF and the control linear pe

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Drögemüller, Cord, Anne Wöhlke, Tosso Leeb, and Ottmar Distl. "A4Mb High Resolution BAC Contig on Bovine Chromosome1q12and Comparative Analysis With Human Chromosome21q22." Comparative and Functional Genomics 6, no. 4 (2005): 194–203. http://dx.doi.org/10.1002/cfg.476.

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The bovine RPCI-42 BAC library was screened to construct a sequence-ready ~4 Mb single contig of 92 BAC clones on BTA 1q12. The contig covers the region between the genesKRTAP8P1andCLIC6. This genomic segment in cattle is of special interest as it contains the dominant gene responsible for the hornless or polled phenotype in cattle. The construction of the BAC contig was initiated by screening the bovine BAC library with heterologous cDNA probes derived from 12 human genes of the syntenic region on HSA 21q22. Contig building was facilitated by BAC end sequencing and chromosome walking. During

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Whelan, Sean P. J., and Gail W. Wertz. "The 5′ Terminal Trailer Region of Vesicular Stomatitis Virus Contains a Position-Dependent cis-Acting Signal for Assembly of RNA into Infectious Particles." Journal of Virology 73, no. 1 (1999): 307–15. http://dx.doi.org/10.1128/jvi.73.1.307-315.1999.

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ABSTRACT The cis-acting genomic RNA requirements for the assembly of vesicular stomatitis virus (VSV) ribonucleocapsids into infectious particles were investigated. Using a biological assay based on particle infectivity, we demonstrated that subgenomic replicons that contained all four possible combinations of the natural genomic termini, the 3′ leader (Le) and 5′ trailer (Tr) regions, were replication competent; however, a 3′ copyback replicon (3′CB), containing the natural 3′ terminus but having the 5′ Tr replaced by a sequence complementary to the 3′ Le for 46 nucleotides, was unable to ass

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Malousi, Andigoni, Vassilis Koutkias, and Nicos Maglaveras. "Managing Evidence from Multiple Gene Finding Resources via an XML-based Integration Architecture." Journal of Integrative Bioinformatics 2, no. 1 (2005): 74–83. http://dx.doi.org/10.1515/jib-2005-16.

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SummaryWhile biological processes underlying gene expression are still under experimental research, computational gene prediction techniques have reached high level of sophistication with the employment of efficient intrinsic and extrinsic methods that identify protein-coding regions within query genomic sequences. Their ability though to delineate the exact exon boundaries is characterized by a trade off between sensitivity and specificity and still is prone to alternations in gene regulation during transcription and splicing and to inherent complexities introduced by the implemented methodol

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Ding, Qiulan, Guoling You, Jing Dai, et al. "Characterisation of large F9 deletions in seven unrelated patients with severe haemophilia B." Thrombosis and Haemostasis 112, no. 09 (2014): 459–65. http://dx.doi.org/10.1160/th13-12-1060.

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SummaryLarge deletions in the F9 gene are detected in approximately 5% of patients with severe haemophilia B, but only a few deletion breakpoints have been characterised precisely until now. In this study we identified a total of seven large F9 deletions in the index patients and nine female carriers by the AccuCopy technique. We also successfully characterised the exact breakpoints for each large deletion including four deletions encompassing the entire F9 gene by the genome walking method combined with primer walking strategy. The extents of deletion regions ranged from 11.1 to 884 kb. Micro

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Dousa, T. P., E. N. Chini, and K. W. Beers. "Adenine nucleotide diphosphates: emerging second messengers acting via intracellular Ca2+ release." American Journal of Physiology-Cell Physiology 271, no. 4 (1996): C1007—C1024. http://dx.doi.org/10.1152/ajpcell.1996.271.4.c1007.

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Release of Ca2+ from intracellular stores is a widespread mechanism in regulation of cell function. Two hitherto unknown adenine diphosphonucleotides were recently identified, which trigger Ca2+ release from intracellular stores via channels that are distinct from the well-known receptor/channel controlled by inositol 1,4,5,-trisphosphate (IP3): cyclic ADP-ribose (cADPR) and nicotinic acid adenine dinucleotide phosphate (NAADP). Here we review synthesis of cADPR from beta-NAD, its hydrolysis to adenosine diphosphoribose (noncyclic) by cADPR glycohydrolase, as well as our knowledge about the me

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Li, Aihong, Jianbiao Zhou, Hongjun Wang, et al. "Molecular Analysis of T-Cell Receptor Gene Rearrangements in Children with T-Cell Acute Lymphoblast Leukemia on DFCI ALL Consortium Protocol 95-01." Blood 104, no. 11 (2004): 1084. http://dx.doi.org/10.1182/blood.v104.11.1084.1084.

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Abstract During normal T-cell differentiation, T-cell receptor (TCR) genes undergo recombination in an ordered way. TCRd genes rearrange first followed by TCRg genes, which may result in TCRgd+ T lymphocytes. TCRab T lymphocytes develop via a separate differentiation lineage, with TCRb preceding TCRa gene rearrangements. Unlike in normal T-cells, TCRd, TCRg and TCRb genes rearrangements can be detected in T-cell acute lymphoblastic leukemia (T-ALL) and these rearranged gene sequences can be used as molecular targets to detect minimal residual disease (MRD). Knowledge of the association between

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Laufs, Stephanie, Frank A. Giordano, Agnes Hotz-Wagenblatt, et al. "Automated Retroviral Insertion Site Sequence Analysis and Mapping Tool Followed by Database Analysis." Blood 106, no. 11 (2005): 5528. http://dx.doi.org/10.1182/blood.v106.11.5528.5528.

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Abstract Increasing use of retroviral vector-mediated gene transfer and recent reports on insertional mutagenesis in mice and humans created intense interest to characterize vector integrations on the genomic level. Techniques to determine insertion sites, mainly based on time consuming manual data processing and compilation, are thus commonly applied in gene therapy laboratories. Since a high variability in processing methods hampers further data comparison, there is an urgent need to systematically process the data arising from such analysis. The obtained sequences from the integration site

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Chen, Bo, Huaijie Zhu, Wei Liu, Jian Yin, Wang-Chien Lee, and Jianliang Xu. "Querying Optimal Routes for Group Meetup." Data Science and Engineering 6, no. 2 (2021): 180–91. http://dx.doi.org/10.1007/s41019-021-00153-5.

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AbstractMotivated by location-based social networks which allow people to access location-based services as a group, we study a novel variant of optimal sequenced route (OSR) queries, optimal sequenced route for group meetup (OSR-G) queries. OSR-G query aims to find the optimal meeting POI (point of interest) such that the maximum users’ route distance to the meeting POI is minimized after each user visits a number of POIs of specific categories (e.g., gas stations, restaurants, and shopping malls) in a particular order. To process OSR-G queries, we first propose an OSR-Based (OSRB) algorithm

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Icken, W., S. Thurner, D. Cavero, M. Schmutz, G. Wendl, and R. Preisinger. "Genetische Analyse des Legemusters in der Bodenhaltung im Hinblick auf neue Leistungsprüfungskriterien für die Legehennenzucht." Archives Animal Breeding 52, no. 2 (2009): 187–99. http://dx.doi.org/10.5194/aab-52-187-2009.

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Abstract. Title of the paper: Genetic analysis of the laying pattern in floor management in terms of new performance parameters for breeding In order to facilitate a specific selection of laying hens which are suitable for alternative housing systems, it will be of advantage if the individual hens were tested in their later husbandry environment. Therefore, a new technology has been developed, the »Weihenstephan Funnel Nest Box«, which enables the automatic recording of these essential performance and nesting behaviour parameters of the individual hens in a group housing system. The exact ovip

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Dowd, Peter A., and Eulogio Pardo-Igúzquiza. "Estimating the boundary surface between geologic formations from 3D seismic data using neural networks and geostatistics." GEOPHYSICS 70, no. 1 (2005): P1—P11. http://dx.doi.org/10.1190/1.1852783.

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The exact locations of horizons that separate geologic sequences are known only at physically sampled locations (e.g., borehole intersections), which, in general, are very sparse. 3D seismic data, on the other hand, provide complete coverage of a volume of interest with the possibility of detecting the boundaries between formations with, for example, contrasted acoustic impedance. Detection of boundaries is hampered, however, by coarse spatial resolution of the seismic data, together with local variability of acoustic impedance within formations. The authors propose a two-part approach to the

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Baer, Constance Regina, Niroshan Nadarajah, Claudia Haferlach, Wolfgang Kern, and Torsten Haferlach. "A Study on Paired Tissue Sequencing in Hematologic Diseases to Distinguish Somatic from Germline Sequence Variants in Routine Diagnostics." Blood 128, no. 22 (2016): 5511. http://dx.doi.org/10.1182/blood.v128.22.5511.5511.

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Abstract Background: Genetic testing is an integral part of modern diagnostics. Sequencing genomes or exomes in different consortia revealed novel aberrations with importance to hematologic classification, prognosis or therapy. However, a high number of low frequency variants were also found in healthy populations. This challenged the distinction between population variation (polymorphism) and disease associated changes based on early databases with limited extent. For diagnostic purposes, the distinction of somatic (acquired) variants from rare germline variants allows moving towards personal

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Dickins, J. M. "IGCP 272 - Late Palaeozoic and Early Mesozoic circum-Pacific events and their global correlation." Paleontological Society Special Publications 6 (1992): 85. http://dx.doi.org/10.1017/s2475262200006456.

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IGCP 203 - Permo-Triassic events of eastern Tethys and their intercontinental correlation - focussed on the Permian-Triassic boundary sequences and in particular there was a consensus that the distinctive biological changes were associated with strong sea-level and tectonic change, strong volcanic activity and a harsh climate. These factors were connected with an important change in the environment and with the exception perhaps of the climate, reflected deep-seated changes within the earth. The project also resulted in improving the physical understanding of the sequences and their biostratig

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Roy, Pushpita, and Ansuman Banerjee. "A Framework for Validation of Synthesized MicroElectrode Dot Array Actuations for Digital Microfluidic Biochips." ACM Transactions on Design Automation of Electronic Systems 26, no. 6 (2021): 1–36. http://dx.doi.org/10.1145/3460437.

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Digital Microfluidics is an emerging technology for automating laboratory procedures in biochemistry. With more and more complex biochemical protocols getting mapped to biochip devices and microfluidics receiving a wide adoption, it is becoming indispensable to develop automated tools and synthesis platforms that can enable a smooth transformation from complex cumbersome benchtop laboratory procedures to biochip execution. Given an informal/semi-formal assay description and a target microfluidic grid architecture on which the assay has to be implemented, a synthesis tool typically translates t

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POURSAFAR, ALIREZA, ESMAEIL HASHEMLOU, YOUBERT GHOSTA, FATEMEH SALIMI, and MOHAMMAD JAVAN-NIKKHAH. "Alternaria guilanica sp. nov., a new fungal pathogen causing leaf spot and blight on eggplant in Iran." Phytotaxa 520, no. 2 (2021): 184–94. http://dx.doi.org/10.11646/phytotaxa.520.2.5.

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Eggplant (Solanum melongena L.) is an economically important solanaceous crop in Iran with fruits used for food and traditional medicine. Despite the importance of Alternaria leaf spot and blight disease of solanaceous crops which is commonly seen in the fields, our knowledge about the causal agents on eggplant is limited. In this study, a set of large-spored Alternaria isolates was recovered from eggplant with leaf spot and blight symptoms in Somehsara region, Guilan province, Iran. All recovered isolates shared conspicuous morphological characteristics e.g. production of large, solitary coni

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Poruchynsky, M. S., and P. H. Atkinson. "Primary sequence domains required for the retention of rotavirus VP7 in the endoplasmic reticulum." Journal of Cell Biology 107, no. 5 (1988): 1697–706. http://dx.doi.org/10.1083/jcb.107.5.1697.

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Rotavirus VP7 is a membrane-associated protein of the endoplasmic reticulum (ER). It is the product of rotavirus gene 9 which potentially encodes a protein of 326 amino acids that contains two amino terminal hydrophobic domains, h1 and h2, each preceded by an initiation codon. Comparison of the size of products derived from altered genes containing coding sequences for both h1 and h2 with those lacking the h1 sequence ('dhl' mutants), indicates that initiation takes place at M30 immediately preceding h2 (residues F32 to L48) and that h2 is cleaved, confirming the studies of others (Stirzaker,

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