Log in

Relevant bibliographies by topics / Excitatory amino acid transporter 1 / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Excitatory amino acid transporter 1.

Dissertations / Theses on the topic 'Excitatory amino acid transporter 1'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 18 dissertations / theses for your research on the topic 'Excitatory amino acid transporter 1.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Richards, Dannette Shanon. "CHARACTERIZATION OF EXCITATORY AMINO ACID NEUROTRANSMITTERS AT MOTONEURON SYNAPSES CONTACTING RENSHAW CELLS." Wright State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=wright1260896604.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Ye, Ran. "Mass Spectrometric Characterization and Fluorophore-Assisted Light Inactivation of Human Excitatory Amino Acid Transporter." The University of Montana, 2009. http://etd.lib.umt.edu/theses/available/etd-05192009-104425/.

Full text

Abstract:

Glia-expressing excitatory amino acid transporter 2 (EAAT2) mediates the bulk of glutamate re-uptake in the human central nervous system (CNS) and is associated with a variety of neurological disorders. Our understanding of the structure and mechanism of this integral membrane protein is limited. The goal of this study was to use pharmacological, mass spectrometric (MS) and photochemical approaches to probe EAAT2. For MS characterization, a hexahis epitope was incorporated into the N-terminus of human EAAT2. The recombinant protein was functionally expressed in HEK 293T cells and purified thro

APA, Harvard, Vancouver, ISO, and other styles

3

Leinenweber, Ariane [Verfasser]. "Regulation of Excitatory Amino Acid Transporter 2 (EAAT2) by Carboxy-terminal Domains / Ariane Leinenweber." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2010. http://d-nb.info/100962427X/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Mavencamp, Terri Lynn. "Design, synthesis and biological evaluation of a family of excitatory amino acid transporter 3 (EAAT3) preferring inhibitors." [Missoula, Mont.] : The University of Montana, 2008. http://etd.lib.umt.edu/theses/available/etd-03212009-152926/unrestricted/Mavencamp_umt_0136D_10009.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Mavencamp, Terri Lynn. "Design, Synthesis and Biological Evaluation of a Family of Excitatory Amino Acid Transporter 3 (EAAT3) Preferring Inhibitors." The University of Montana, 2009. http://etd.lib.umt.edu/theses/available/etd-03212009-152926/.

Full text

Abstract:

<p>This work describes the synthesis and initial characterization of the biological activity of a family of EAAT3 preferring inhibitors, L-β-benzyl aspartate (L-β-BA) and L-β-BA derivatives. L-β-BA and derivatives were initially synthesized in an approximate 2:1 ratio of diasteromers (threo:erythro), using base promoted enolate addition. Kinetic analysis of 3H-D-aspartate uptake into C17.2 cells expressing the hEAATs demonstrated that L-threo-β-BA is the more potent diastereomer (Ki values of 9 µM for EAAT1, 10.0 µM for EAAT2 and 0.8 µM for EAAT3), acts competitively,

APA, Harvard, Vancouver, ISO, and other styles

6

Barcelona, Stephanie Suazo. "Investigation of the Mechanism of Substrate Transport by the Glutamate Transporter EAAC1." Scholarly Repository, 2007. http://scholarlyrepository.miami.edu/oa_theses/91.

Full text

Abstract:

The activity of glutamate transporters is essential for the temporal and spatial regulation of the neurotransmitter concentration in the synaptic cleft which is critical for proper neuronal signaling. Because of their role in controlling extracellular glutamate concentrations, dysfunctional glutamate transporters have been implicated in several neurodegenerative diseases and psychiatric disorders. Therefore, investigating the mechanism of substrate transport by these transporters is essential in understanding their behavior when they malfunction. A bacterial glutamate transporter hom

APA, Harvard, Vancouver, ISO, and other styles

7

Tian, Guilian. "The molecular mechanisms of the loss of glial glutamate transporter EAAT2 in neurodegenerative diseases." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1187038549.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Akohene-Mensah, Paul. "Examining the Role of L-Type Amino Acid Transporter 1 (SLC7A5) in Myoblasts." Thesis, Université d'Ottawa / University of Ottawa, 2020. http://hdl.handle.net/10393/41036.

Full text

Abstract:

Skeletal muscles represent the largest tissue mass within the body and are primarily involved in the generation of force for voluntary movement. Skeletal muscles have a remarkable capacity to repair, due primarily to the actions of muscle stem cells (MuSCs). MuSCs are normally quiescent in adult skeletal muscle; however, in response to myotrauma (trauma to muscle tissue) from muscle injury or exercise, MuSCs become activated, either undergo self-renewal to replenish the quiescent population or commit to the myogenic lineage as myoblasts, proliferate, and differentiate into myotubes in vitro or

APA, Harvard, Vancouver, ISO, and other styles

9

Butchbach, Matthew E. R. "Regulation of glutamate transport by GTRAP3-18 and by lipid rafts." Connect to this title online, 2003. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1054650123.

Full text

Abstract:

Thesis (Ph. D.)--Ohio State University, 2003.<br>Title from first page of PDF file. Document formatted into pages; contains xviii, 160 p.; also includes graphics Includes bibliographical references (p. 132-160). Available online via OhioLINK's ETD Center

APA, Harvard, Vancouver, ISO, and other styles

10

Linderholm, Klas. "Kynurenic acid in psychiatric disorders studies on the mechanisms of action /." Stockholm, 2010. http://diss.kib.ki.se/2010/978-91-7409-818-1/.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Foster, Joshua B. "Development of Pyridazine-Derivatives for the Treatment of Neurological Disorders." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1545904228813231.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Huang, Charlie Chia Wei. "Regulation of Cat-1 gene transcription during physiological and pathological conditions." Case Western Reserve University School of Graduate Studies / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=case1270242874.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Benner, Jacqueline [Verfasser], Hannelore [Akademischer Betreuer] Daniel, Dirk [Akademischer Betreuer] Haller, and Michael [Akademischer Betreuer] Schemann. "Amino acid homeostasis in Caenorhabditis elegans lacking the intestinal peptide transporter PEPT-1 and identification of PEPT-1 modulator proteins / Jacqueline Benner. Gutachter: Hannelore Daniel ; Dirk Haller ; Michael Schemann. Betreuer: Hannelore Daniel." München : Universitätsbibliothek der TU München, 2011. http://d-nb.info/1056935480/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Kim, Seol-Hee. "Acetaminophen Associated Neurotoxicity and its Relevance to Neurodevelopmental Disorders." Scholar Commons, 2017. http://scholarcommons.usf.edu/etd/6717.

Full text

Abstract:

Autism is a lifelong neurodevelopmental disorder. The etiology of autism still remains unclear due to the heterogeneous and complex nature of the disorder, however synergistic actions between genetic components and environmental factors have been suggested. Acetaminophen (APAP) is one of the most popular over-the-counter drugs that possess antipyretic and analgesic effects. It is considered a relatively safe and effective within therapeutic doses. Recently, early exposure to APAP has been suggested to be one of the underlying cause of autism. Children are often prescribed APAP to lessen fever

APA, Harvard, Vancouver, ISO, and other styles

15

Peacey, E., C. C. Miller, J. Dunlop, and Marcus Rattray. "The four major N- and C-terminal splice variants of the excitatory amino acid transporter GLT-1 form cell surface homomeric and heteromeric assemblies." 2009. http://hdl.handle.net/10454/6126.

Full text

Abstract:

The L-glutamate transporter GLT-1 is an abundant central nervous system (CNS) membrane protein of the excitatory amino acid transporter (EAAT) family that controls extracellular L-glutamate levels and is important in limiting excitotoxic neuronal death. Using reverse transcription-polymerase chain reaction, we have determined that four mRNAs encoding GLT-1 exist in mouse brain, with the potential to encode four GLT-1 isoforms that differ in their N and C termini. We expressed all four isoforms (termed MAST-KREK, MPK-KREK, MAST-DIETCI, and MPK-DIETCI according to amino acid sequence) in a range

APA, Harvard, Vancouver, ISO, and other styles

16

Carbone, M., S. Duty, and Marcus Rattray. "Riluzole elevates GLT-1 activity and levels in striatal astrocytes." 2012. http://hdl.handle.net/10454/5907.

Full text

Abstract:

Drugs which upregulate astrocyte glutamate transport may be useful neuroprotective compounds by preventing excitotoxicity. We set up a new system to identify potential neuroprotective drugs which act through GLT-1. Primary mouse striatal astrocytes grown in the presence of the growth-factor supplement G5 express high levels of the functional glutamate transporter, GLT-1 (also known as EAAT2) as assessed by Western blotting and (3)H-glutamate uptake assay, and levels decline following growth factor withdrawal. The GLT-1 transcriptional enhancer dexamethasone (0.1 or 1 muM) was able to prevent l

APA, Harvard, Vancouver, ISO, and other styles

17

"Design, synthesis and biological evaluation of a family of excitatory amino acid transporter 3 (EAAT3) preferring inhibitors." UNIVERSITY OF MONTANA, 2009. http://pqdtopen.proquest.com/#viewpdf?dispub=3338786.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Chang, Hsuan, and 張軒. "The Role of Growth Associated Protein-43 in the Expression of Aquaporin-4 and Excitatory Amino Acid Transporter-2 in Astrocytes." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/37884309087764082055.

Full text

Abstract:

碩士<br>國立陽明大學<br>生理學研究所<br>100<br>Astrocytes play critical roles in maintaining homeostasis in the microenvironment of the central nervous system including regulations of water and extracellular neurotransmitter concentrations. Astrocytes are equipped with aquaporin-4 (AQP4) to regulate the water flow across cell membrane, and excitatory amino acid transporter-2 (EAAT2) to keep external glutamate at low concentration to avoid excitotoxicity. During CNS insults such as brain trauma, stroke or infection, astrocytes become reactive and hypertrophic with the molecular expression and functional acti

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!