Academic literature on the topic 'Exogenous surfactant therapy'

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Journal articles on the topic "Exogenous surfactant therapy"

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Suresh, G. K., and R. F. Soll. "Exogenous Surfactant Therapy in Newborn Infants." Annals of the Academy of Medicine, Singapore 32, no. 3 (2003): 335–45. http://dx.doi.org/10.47102/annals-acadmedsg.v32n3p335.

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Exogenous surfactant therapy has an established role in the management of neonatal respiratory distress syndrome (RDS). This article summarises the current evidence on surfactant therapy. The use of surfactant for the treatment or prophylaxis of neonatal RDS results in a 30% to 65% relative reduction in the risk of pneumothorax and up to a 40% relative reduction in the risk of mortality. Adverse effects, of which pulmonary haemorrhage is of most concern, are infrequent and long-term follow-up studies of treated patients are reassuring. Natural surfactants have advantages over synthetic surfact
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Dipak, Kumar Dhar, and Paul Debasish. "Surfactant Replacement Therapy: An Overview." International Journal of Science and Healthcare Research 5, no. 2 (2020): 399–406. https://doi.org/10.5281/zenodo.3931623.

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Pulmonary surfactant is a soap-like chemical synthesized by type II alveolar pneumocytes and is a mixture of phospholipids (predominantly dipalmitoylphosphatidylcholine), some other lipids and proteins. Its main functions include lowering the surface tension and maintaining the stability of alveoli. The first documented trial involving exogenous use of surfactants as a therapy was recorded in early 1970s using synthetically produced phospholipid mixtures once the chemical composition of surfactants was deciphered. Gradually there was a transition to the use of more natural sources. And animal
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Merritt, T. Allen, and Henry L. Halliday. "On exogenous surfactant therapy." Pediatric Pulmonology 14, no. 1 (1992): 1–3. http://dx.doi.org/10.1002/ppul.1950140102.

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Grotberg, J. B., D. Halpern, and O. E. Jensen. "Interaction of exogenous and endogenous surfactant: spreading-rate effects." Journal of Applied Physiology 78, no. 2 (1995): 750–56. http://dx.doi.org/10.1152/jappl.1995.78.2.750.

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The spreading rate of an exogenous surfactant monolayer due to surface tension gradients is examined by using our previously reported theoretical analysis, with particular attention given to the effects of endogenous surfactant. It is found that the presence of an endogenous surfactant reduces the spreading rate of exogenous surfactant and that, in certain circumstances, the spreading may be halted. A recently published paper (F. F. Espinosa, A. H. Shapiro, J. J. Fredberg, and R. D. Kamm. J. Appl. Physiol. 75: 2028–2039, 1993) reaches the opposite conclusion about the effect of endogenous surf
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Freddi, Norberto A., José Oliva Proença Filho, and Humberto H. Fiori. "Exogenous surfactant therapy in pediatrics." Jornal de Pediatria 79, no. 8 (2003): 205–12. http://dx.doi.org/10.2223/jped.1097.

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Maruscak, Adam, and Jim F. Lewis. "Exogenous surfactant therapy for ARDS." Expert Opinion on Investigational Drugs 15, no. 1 (2005): 47–58. http://dx.doi.org/10.1517/13543784.15.1.47.

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Lacaze-Masmonteil, Thierry. "Exogenous surfactant therapy: newer developments." Seminars in Neonatology 8, no. 6 (2003): 433–40. http://dx.doi.org/10.1016/s1084-2756(03)00120-9.

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Froese, Alison B. "Exogenous Surfactant Therapy in ARDS." Chest 105, no. 5 (1994): 1310–12. http://dx.doi.org/10.1378/chest.105.5.1310.

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Ramanathan, Rangasamy. "Surfactants in the Management of Respiratory Distress Syndrome in Extremely Premature Infants." Journal of Pediatric Pharmacology and Therapeutics 11, no. 3 (2006): 132–44. http://dx.doi.org/10.5863/1551-6776-11.3.132.

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Respiratory distress syndrome (RDS) is primarily due to decreased production of pulmonary surfactant, and it is associated with significant neonatal morbidity and mortality. Exogenous pulmonary surfactant therapy is currently the treatment of choice for RDS, as it demonstrates the best clinical and economic outcomes. Studies confirm the benefits of surfactant therapy to include reductions in mortality, pneumothorax, and pulmonary interstitial emphysema, as well as improvements in oxygenation and an increased rate of survival without bronchopulmonary dysplasia. Phospholipids (PL) and surfactant
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Willson, D. F., and R. H. Notter. "The Future of Exogenous Surfactant Therapy." Respiratory Care 56, no. 9 (2011): 1369–88. http://dx.doi.org/10.4187/respcare.01306.

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Dissertations / Theses on the topic "Exogenous surfactant therapy"

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Espinosa, Frank F. (Frank Francis). "Exogenous surfactant transport through the pulmonary airways : improving surfactant replacement therapy for neonatal respiratory distress syndrome." Thesis, Massachusetts Institute of Technology, 1996. http://hdl.handle.net/1721.1/10974.

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Duncan, Jason E. "The vasoactive potential of lysophosphatidylcholine, a product of surfactant degradation in the lung, on the pulmonary vasculature following exogenous surfactant replacement therapy for neonatal respiratory distress syndrome." 1995. http://hdl.handle.net/1993/17634.

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Book chapters on the topic "Exogenous surfactant therapy"

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Strohmaier, W., H. Redl, and G. Schlag. "Efficacy of Exogenous Surfactant in Experimental Aspiration Trauma." In Surfactant Replacement Therapy. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73305-5_29.

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Southall, D. P., M. Samuels, and D. G. Talbert. "Alveolar Atelectasis as a Mechanism for Infantile Apnoea: A Possible Role for Exogenous Surfactant Therapy?" In Surfactant Replacement Therapy. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73305-5_23.

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Walther, F. J. "Distribution of Exogenous Surfactant in Premature Lambs: High-Frequency Oscillation Ventilation Versus Conventional Mechanical Ventilation." In Surfactant Replacement Therapy. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73305-5_33.

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Oetomo, S. Bambang, L. de Ley, C. Schoots, B. Lachmann, and A. Okken. "Immunohistochemical Study of the Distribution of Exogenous Surfactant in the Lungs of Surfactant-Deficient Rabbits Using a Monoclonal Antibody." In Surfactant Replacement Therapy. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73305-5_34.

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Lachmann, B., O. D. Saugstad, J. Klein, and W. Erdmann. "Acute Respiratory Failure Induced by Tracheal Instillation of Xanthine Oxidase, its Prevention and Therapy by Exogenous Surfactant Instillation." In Oxygen Transport to Tissue IX. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-7433-6_41.

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Gautham, K. Suresh, and Roger F. Soll. "Exogenous surfactant therapy." In Goldsmith's Assisted Ventilation of the Neonate. Elsevier, 2022. http://dx.doi.org/10.1016/b978-0-323-76177-2.00024-6.

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Conference papers on the topic "Exogenous surfactant therapy"

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Muradoglu, Metin, and Ufuk Olgac. "Computational Modeling of Surfactant-Laden Liquid Plug Propagation in Capillary Tubes." In ASME 2012 10th International Conference on Nanochannels, Microchannels, and Minichannels collocated with the ASME 2012 Heat Transfer Summer Conference and the ASME 2012 Fluids Engineering Division Summer Meeting. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/icnmm2012-73039.

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Pulmonary surfactant is of essential importance in reducing the surface tension on the liquid film that coats the inner surface of the airways and thus making the lung more compliant. Surfactant-deficiency may result in respiratory distress syndrome (RDS), which is especially common in prematurely born neonates. Surfactant replacement therapy (SRT) is a standard treatment, in which a liquid plug with exogenous surfactant is instilled in the trachea, which subsequently propagates by inspiration and spreads the exogenous surfactant to the airways. The efficacy of the treatment depends on various
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Mapindra, Muhammad Pradhika, Muhammad Pradhiki Mahindra, and Mahendra Tri Arif Sampurna. "8377 Impact of exogenous surfactant therapy in neurodevelopmental outcomes of preterm babies – a systematic review and meta analysis." In Royal College of Paediatrics and Child Health, Abstracts of the RCPCH Conference, Glasgow, 26 March 2025 – 28 March 2025. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2025. https://doi.org/10.1136/archdischild-2025-rcpch.173.

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