Relevant bibliographies by topics / Exons Introns

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Exons Introns'

Author: Grafiati
Published: 4 June 2021
Last updated: 10 February 2022

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Journal articles on the topic "Exons Introns"

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Zhu, D. F., Z. H. Hu, and J. M. Shen. "Moult-Inhibiting Hormone from the Swimming Crab, Portunus Trituberculatus (Miers, 1876): PCR Cloning, Tissue Distribution, and Expression of Recombinant Protein in Escherichia Coli (Migula, 1895)." Crustaceana 84, no. 12-13 (2011): 1481–96. http://dx.doi.org/10.1163/156854011x607051.

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AbstractIn the present study, a genomic DNA of MIH (GenBank: #EU869539) was cloned from the swimming crab, Portunus trituberculatus (Miers, 1876). The genome DNA, consisting of 2865 bp, is comprised of three exons interrupted by two introns. Multiple sequence alignments revealed that in the 5 upstream region of MIH, sequences with high similarity to arthropod initiator, TATA box, CREB (cyclic AMP response element binding) protein were the common structure. The signal peptide in the genomic DNA was encoded by exon1 and exon2, which was interrupted by 242 bp-intron (intron1), located between gln
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Yan, Liuling, Mrinal Bhave, Robert Fairclough, Christine Konik, Sadequr Rahman, and Rudi Appels. "The genes encoding granule-bound starch synthases at the waxy loci of the A, B, and D progenitors of common wheat." Genome 43, no. 2 (2000): 264–72. http://dx.doi.org/10.1139/g99-117.

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Three genes encoding granule-bound starch synthase (wx-TmA, wx-TsB, and wx-TtD) have been isolated from Triticum monococcum (AA), and Triticum speltoides (BB), by the polymerase chain reaction (PCR) approach, and from Triticum tauschii (DD), by screening a genomic DNA library. Multiple sequence alignment indicated that the wx-TmA, wx-TsB, and wx-TtD genes had the same extron and (or) intron structure as the previously reported waxy gene from barley. The lengths of the three wx-TmA, wx-TsB, and wx-TtD genes were 2834 bp, 2826 bp, and 2893 bp, respectively, each covering 31 bp in the untranslate
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Chipens, G., N. Ievina, and I. Kalvinsh. "Internal Regularity of D-Glyceraldehide-3-Phosphate Dehydrogenase Genes and Proteins." Latvian Journal of Chemistry 50, no. 1-2 (2011): 159–64. http://dx.doi.org/10.2478/v10161-011-0061-9.

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Internal Regularity ofD-Glyceraldehide-3-Phosphate Dehydrogenase Genes and ProteinsData of analysis of some GAPDH family gene exon and intron length (nt) and intron position coordinates as a sum of preceeding exon dimensions) and their internal regularity were analyzed based on a working hypothesis that primieval gene precursors were regular and periodic polynucleotides formed from oligonucleotides identical in size. The number of nucleotides in a gene repeat unit was denoted by a specific term - gene quantum and symbolQ. The following genes were analyzed: the chicken GAPDH (12 exons/11 intron
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Long, Manyuan, and Michael Deutsch. "Intron—exon structures of eukaryotic model organisms." Nucleic Acids Research 27, no. 15 (1999): 3219–28. http://dx.doi.org/10.1093/nar/27.15.3219.

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Abstract To investigate the distribution of intron—exon structures of eukaryotic genes, we have constructed a general exon database comprising all available introncontaining genes and exon databases from 10 eukaryotic model organisms: Homo sapiens, Mus musculus, Gallus gallus, Rattus norvegicus, Arabidopsis thaliana, Zea mays, Schizosaccharomyces pombe, Aspergillus, Caenorhabditis elegans and Drosophila . We purged redundant genes to avoid the possible bias brought about by redundancy in the databases. After discarding those questionable introns that do not contain correct splice sites, the fi
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Patthy, László. "Introns and exons." Current Opinion in Structural Biology 4, no. 3 (1994): 383–92. http://dx.doi.org/10.1016/s0959-440x(94)90108-2.

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Wang, Dapeng. "IntronDB: a database for eukaryotic intron features." Bioinformatics 35, no. 21 (2019): 4400–4401. http://dx.doi.org/10.1093/bioinformatics/btz242.

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Abstract Summary The rate and extent of unbalanced eukaryotic intron changes exhibit dynamic patterns for different lineages of species or certain functional groups of genes with varied spatio-temporal expression modes affected by selective pressure. To date, only a few key conserved splicing signals or regulatory elements have been identified in introns and little is known about the remaining intronic regions. To trace the evolutionary trajectory of spliceosomal introns from available genomes under a unified framework, we present IntronDB, which catalogs ∼50 000 000 introns from over 1000 gen
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Ham, Kristin A., May Thandar Aung-Htut, Sue Fletcher, and Steve D. Wilton. "Nonsequential Splicing Events Alter Antisense-Mediated Exon Skipping Outcome in COL7A1." International Journal of Molecular Sciences 21, no. 20 (2020): 7705. http://dx.doi.org/10.3390/ijms21207705.

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The COL7A1 gene encodes homotrimer fibrils essential for anchoring dermal and epidermal layers, and pathogenic mutations in COL7A1 can cause recessive or dominant dystrophic epidermolysis bullosa. As a monogenic disease gene, COL7A1 constitutes a potential target for antisense oligomer-mediated exon skipping, a therapy applicable to a growing number of other genetic disorders. However, certain characteristics of COL7A1: many exons, low average intron size, and repetitive and guanine-cytosine rich coding sequence, present challenges to the design of specific and effective antisense oligomers. W
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Robberson, B. L., G. J. Cote, and S. M. Berget. "Exon definition may facilitate splice site selection in RNAs with multiple exons." Molecular and Cellular Biology 10, no. 1 (1990): 84–94. http://dx.doi.org/10.1128/mcb.10.1.84.

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Interactions at the 3' end of the intron initiate spliceosome assembly and splice site selection in vertebrate pre-mRNAs. Multiple factors, including U1 small nuclear ribonucleoproteins (snRNPs), are involved in initial recognition at the 3' end of the intron. Experiments were designed to test the possibility that U1 snRNP interaction at the 3' end of the intron during early assembly functions to recognize and define the downstream exon and its resident 5' splice site. Splicing precursor RNAs constructed to have elongated second exons lacking 5' splice sites were deficient in spliceosome assem
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Robberson, B. L., G. J. Cote, and S. M. Berget. "Exon definition may facilitate splice site selection in RNAs with multiple exons." Molecular and Cellular Biology 10, no. 1 (1990): 84–94. http://dx.doi.org/10.1128/mcb.10.1.84-94.1990.

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Interactions at the 3' end of the intron initiate spliceosome assembly and splice site selection in vertebrate pre-mRNAs. Multiple factors, including U1 small nuclear ribonucleoproteins (snRNPs), are involved in initial recognition at the 3' end of the intron. Experiments were designed to test the possibility that U1 snRNP interaction at the 3' end of the intron during early assembly functions to recognize and define the downstream exon and its resident 5' splice site. Splicing precursor RNAs constructed to have elongated second exons lacking 5' splice sites were deficient in spliceosome assem
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Talerico, M., and S. M. Berget. "Intron definition in splicing of small Drosophila introns." Molecular and Cellular Biology 14, no. 5 (1994): 3434–45. http://dx.doi.org/10.1128/mcb.14.5.3434.

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Approximately half of the introns in Drosophila melanogaster are too small to function in a vertebrate and often lack the pyrimidine tract associated with vertebrate 3' splice sites. Here, we report the splicing and spliceosome assembly properties of two such introns: one with a pyrimidine-poor 3' splice site and one with a pyrimidine-rich 3' splice site. The pyrimidine-poor intron was absolutely dependent on its small size for in vivo and in vitro splicing and assembly. As such, it had properties reminiscent of those of yeast introns. The pyrimidine-rich intron had properties intermediate bet
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Dissertations / Theses on the topic "Exons Introns"

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Taylor, Pamela A. 1941. "Exon/Intron Discrimination Using the Finite Induction Pattern Matching Technique." Thesis, University of North Texas, 1997. https://digital.library.unt.edu/ark:/67531/metadc277629/.

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DNA sequence analysis involves precise discrimination of two of the sequence's most important components: exons and introns. Exons encode the proteins that are responsible for almost all the functions in a living organism. Introns interrupt the sequence coding for a protein and must be removed from primary RNA transcripts before translation to protein can occur. A pattern recognition technique called Finite Induction (FI) is utilized to study the language of exons and introns. FI is especially suited for analyzing and classifying large amounts of data representing sequences of interest. It
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Miller, James Keith. "Exon and intron detection in human genomic DNA." Online access for everyone, 2005. http://www.dissertations.wsu.edu/Dissertations/Spring2005/j%5Fmiller%5F030705.pdf.

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Desseyn, Jean-Luc. "Organisation du gène de mucine humaine MUC5B : bases moléculaires d'une nouvelle classification des mucines." Lille 1, 1997. http://www.theses.fr/1997LIL10151.

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Le gène humain MUC5B, localise avec muc6, muc2 et muc5ac en 11p15 code une grande mucine qui forme le gel de mucus. Il s'étend sur plus de 36,5 kb. La répartition complète exon-intron a été déterminée. Le gène comprend 48 exons qui ont des tailles comprises entre 32 et 10713 pb. Les 47 introns ont des tailles comprises entre 87 pb et 1,7 kb. Tous les introns, a l'exception de l'intron 8, ont des sites d'epissage conformes au site consensus gt/ag. Le peptide déduit de la région centrale (3570 aa) est compose de 19 sous-domaines. Certains ont des similarités entre eux et l'alternance de 3 sous-d
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Souza, Alessandra Finardi de. "Caracterização de metaloproteinases PIII a partir do DNA genômico de Bothrops jararaca." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/87/87131/tde-27092011-140544/.

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O veneno de Bothops jararaca contém uma série de componentes, entre eles as metaloproteinases hemorrágicas jararagina e bothropasina. Os cDNAs dessas toxinas mostram 97% de identidade. As diferenças, distribuídas ao longo de seus cDNAs, sugerem que estes mRNas não resultam de splicing alternativo. O objetivo deste trabalho foi caracterizar os genes codificadores da jararagina e bothropasina pela identificação de exons e introns no DNA genômico. DNA foi extraído do sangue de um exemplar de B. jararaca; os primers para PCR foram baseados nos cDNAs publicados. Os produtos de amplificação foram cl
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Choi, Eun-Young Pintel David J. "Determinants that govern alternative splicing of the large intron of minute virus of mice p4-generated PRE-mRNA." Diss., Columbia, Mo. : University of Missouri--Columbia, 2008. http://hdl.handle.net/10355/6696.

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Title from PDF of title page (University of Missouri--Columbia, viewed on Feb 25, 2010). The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file. Dissertation advisor: David J. Pintel. Vita. Includes bibliographical references.
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Haut, Donald David. "Small intron definition of MVM pre-mRNAs." free to MU campus, to others for purchase, 1998. http://wwwlib.umi.com/cr/mo/fullcit?p9904845.

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Robinson, Robert Maxwell. "Splicing signals in Caenorhabditis elegans : candidate exonic splicing enhancer motifs /." Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/10846.

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Gersappe, Anand. "An analysis of genetic determinants that govern exon definition and alternative splicing of minute virus of mice (MVM) pre-mRNAs." free to MU campus, to others for purchase, 1998. http://wwwlib.umi.com/cr/mo/fullcit?p9904842.

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Barreaud, Jean-Pierre. "Les gènes de fucosyltransférases de Bos taurus : Organisation et expression de trois gènes (fut1, fut2, sec1) d'alpha2-fucosyltransférases." Limoges, 1999. http://www.theses.fr/1999LIMO0039.

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Chez l'homme, le fucose lie en 1,2 sur des glycoproteines ou des glycolipides joue un role majeur dans de nombreux processus cellulaires comme la differenciation et la maturation, les interactions hote-pathogenes ou la definition du systeme de groupes sanguins abh. Afin d'elucider le role des molecules 2-fucosylees chez l'espece bovine, nous avons isole plusieurs adn complementaires de differents tissus. Ces adnc correspondent a trois genes, fut1b, fut2b et sec1b qui sont les homologues respectifs des genes humains fut1, fut2 et sec1. Leur cadre ouvert de lecture code respectivement des protei
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Wierinckx, Anne. "Les gènes de fucosyltransférases de Bos Taurus "Organisation et expression d'un gène (futb) d'alpha 3-fucosyltransférase"." Limoges, 1999. http://www.theses.fr/1999LIMO0004.

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Le gene futb est constitue de 5 exons dont quatre sont non traduits et de 4 introns repartis sur 10 kpb. Seul un gene, correspondant aux trois genes humains fut3, fut5 et fut6, est identifie dans le genome bovin et serait ainsi l'homologue orthologue de l'ancetre des genes de ce cluster humain. La determination de la structure genomique du gene futb revele la presence de sequences dispersees de type sines dans ses introns. Nous pouvons ainsi avancer l'hypothese d'une duplication des genes de fucosyltransferases chez les primates selon un mecanisme similaire a celui des genes de globines. La de
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Books on the topic "Exons Introns"

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Wills, Christopher. Exons, introns, andtalking genes: The science behind the Human Genome Project. BasicBooks, 1991.

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Wills, Christopher. Exons, introns, and talking genes: The science behind the Human Genome Project. BasicBooks, 1991.

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Wills, Christopher. Exons, introns, and talking genes: The science behind the Human Genome Project. Oxford University Press, 1992.

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Patthy, László. Protein evolution by exon-shuffling. Springer-Verlag, 1995.

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Exons, Introns and Talking Genes: Science Behind the Human Genome Project. Oxford Paperbacks, 1992.

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Wills, Christopher. Exons, Introns, and Talking Genes: The Science Behind the Human Genome Project. Basic Books, 1993.

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Umekage, So. In Vivo Circular RNA Expression by the Permuted Intron-Exon Method. INTECH Open Access Publisher, 2012.

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Association of a nonsense mutation at the codon for Glu 54 in the GM2A gene with AB variant G(M2) gangliosidosis: Characterizing the intron/exon junctions of the gene. National Library of Canada, 1999.

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Book chapters on the topic "Exons Introns"

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Forsdyke, Donald R. "Exons and Introns." In Evolutionary Bioinformatics. Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-7771-7_13.

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Forsdyke, Donald R. "Exons and Introns." In Evolutionary Bioinformatics. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-28755-3_13.

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Forsdyke, Donald R. "Exons and Introns." In Evolutionary Bioinformatics. Springer US, 2006. http://dx.doi.org/10.1007/978-0-387-33419-6_10.

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Samuelsson, Tore. "Exons, Introns, and a Royal Bleeding Disorder." In The Human Genome in Health and Disease. Garland Science, 2019. http://dx.doi.org/10.1201/9780429021732-9.

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Been, M. D., and M. Puttaraju. "Circular RNAs: Generation of Small RNAs with Unique Properties by Splicing Permuted Intron-Exon Sequences." In Nucleic Acids and Molecular Biology. Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-61202-2_8.

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Carmel, Liran, Igor B. Rogozin, Yuri I. Wolf, and Eugene V. Koonin. "An Expectation-Maximization Algorithm for Analysis of Evolution of Exon-Intron Structure of Eukaryotic Genes." In Comparative Genomics. Springer Berlin Heidelberg, 2005. http://dx.doi.org/10.1007/11554714_4.

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Stoltzfus, A. "Introns and Exons." In Encyclopedia of Genetics. Elsevier, 2001. http://dx.doi.org/10.1006/rwgn.2001.0708.

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Stoltzfus, A. "Introns and Exons." In Brenner's Encyclopedia of Genetics. Elsevier, 2013. http://dx.doi.org/10.1016/b978-0-12-374984-0.00814-7.

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Lucchesi, John C. "DNA methylation and gene expression." In Epigenetics, Nuclear Organization & Gene Function. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198831204.003.0008.

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DNA methylation is an epigenetic modification that consists of the addition of a methyl, or of a hydroxyl and a methyl group, to the cytosine of CpG dinucleotides. Some gene promoters are rich in CpGs that are predominantly not modified; other promoters and most enhancers are poor in CpGs. These elements, as well as most exons, introns and intergenic regions, tend to be methylated. CpG methylation plays an important role in maintaining transposable elements and tandem arrays of repetitive sequences in a repressed state. CpG methylation is also responsible for the uniparental silencing of imprinted alleles, allowing the monoallelic expression of some genes, and for the silencing and clonal transmission of the inactive X chromosome in mammals. The use of this modification as a means of dynamically turning individual genes on or off, illustrated by the activation of individual odorant receptor genes, is less common.
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Long, Manyuan, and Sandro J. de Souza. "Intron-exon structures." In Advances in Genome Biology. Elsevier, 1998. http://dx.doi.org/10.1016/s1067-5701(98)80020-x.

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Conference papers on the topic "Exons Introns"

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O'hara, Patrick J., Frank A. Grant, A. Betty, J. Haldmen, and Mark J. Murray. "Structure of the Human Factor VII Gene." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643786.

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Factor VII is a member of a family of vitamin K-dependent, gamma-carboxylated plasma protein which includes factor IX, factor X, protein C, protein S and prothrombin. Activated factor VII (factor Vila) is a plasma serine protease which participates in a cascade of reactions leading to the coagulation of blood. Two overlapping genomic clones containing sequences encoding human factor VII were isolated and characterized. The complete sequence of the gene was determined and found to span 12.8 kilobases. The mRNA for factor VII as demonstrated by cDNA cloning is polyadenylated at multiple sites bu
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Chung, D. W., R. Asakai, and E. W. Davie. "THE ORGANIZATION OF THE HUMAN FACTOR XI GENE: CORRELATION OF INTRON AND EXON LOCATIONS WITH STRUCTURAL DOMAINS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642802.

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Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein that participates in the contact activation of blood coagulation. In the present study, the organization of the gene for human factor XI has been elucidated. The gene for human factor XI has been isolated from two independent human genomic λ phage libraries using a full length cDNA for human factor XI as a hybridization probe. Four overlapping recombinant λ phage containing the human factor XI gene have been isolated and characterized. Restriction mapping, Southern blotting and hybridization studies indicate that the entire
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Pannekoek, H., M. Linders, J. Keijer, H. Veerman, H. Van Heerikhuizen, and D. J. Loskutoff. "THE STRUCTURE OF THE HUMAN ENDOTHELIAL PLASMINOGEN ACTIVATOR INHIBITOR (PAI-1) GENE: NON-RANDOM POSITIONING OF INTRONS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644767.

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The endothelium plays a crucial role in the regulation of the fibrinolytic process, since it synthesizes and secretes tissue-type plasminogen activator (t-PA) as well as the fast-acting plasminogen activator inhibitor (PAI-1). Molecular cloning of full-length PAI-1 cDNA, employing a human endothelial cDNA expression library, and a subsequent determination of the complete nucleotide sequence, allowed a prediction of the amino-acid sequence of the PAI-1 glycoprotein. It was observed that the amino-acid sequence is significantly homologous to those of members of the serine protease inhibitor ("Se
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Ben Nasr, Feriel, and Afef Elloumi Oueslati. "CNN for human exons and introns classification." In 2021 18th International Multi-Conference on Systems, Signals & Devices (SSD). IEEE, 2021. http://dx.doi.org/10.1109/ssd52085.2021.9429303.

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Cool, D. E., and R. T. A. MacGillivray. "CHARACTERIZATION OF THe HUMAN FACTOR XII GENE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642800.

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Surface activation of the plasma systems involved with coagulation, fibrinolysis, renin formation and kinin generation involves factor XII (Hageman factor). This protein is a 76,000 dalton glycoprotein which circulates in plasma as an inactive form of a serine protease. A human liver cDNA coding for factor XII was used to screen a human genomic phage library. Two overlapping clones were isolated, XHXII27 and XHXII76, and contain the entire gene for human factor XII. The gene is 13.5 Kbp in length and consists of 14 exons and 13 introns. The transcriptional start site of the mRNA was determined
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Gupta, Ravi, Ankush Mittal, Kuldip Singh, Prateek Bajpai, and Suraj Prakash. "A Time Series Approach for Identification of Exons and Introns." In 10th International Conference on Information Technology (ICIT 2007). IEEE, 2007. http://dx.doi.org/10.1109/icit.2007.54.

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Gupta, Ravi, Ankush Mittal, Kuldip Singh, Prateek Bajpai, and Suraj Prakash. "A Time Series Approach for Identification of Exons and Introns." In 10th International Conference on Information Technology (ICIT 2007). IEEE, 2007. http://dx.doi.org/10.1109/icoit.2007.4418274.

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Mitra, Uddalak, and Balaram Bhattacharyya. "A new statistical distanceuseful for analyzing exons and introns of eukaryotic genes." In 2016 2nd International Conference on Advances in Electrical, Electronics, Information, Communication and Bio-Informatics (AEEICB). IEEE, 2016. http://dx.doi.org/10.1109/aeeicb.2016.7538289.

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Melia, U. S. P., F. Claria, J. J. Gallardo, P. Caminal, A. Perera, and M. Vallverdu. "Exons and introns characterization in nucleic acid sequences by time-frequency analysis." In 2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2010). IEEE, 2010. http://dx.doi.org/10.1109/iembs.2010.5626756.

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"K11. A New Numerical Mapping Technique for Recognition of Exons and Introns in DNA Sequences." In 2013 30th National Radio Science Conference (NRSC). IEEE, 2013. http://dx.doi.org/10.1109/nrsc.2013.6587955.

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