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1

Greenberg, Marc Samuel. "Defining Benthic Organism Exposure: Bioavailability and Effects of Non-Polar Organics." Wright State University / OhioLINK, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=wright1074096654.

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2

Harrigan, Kristen M. "Scaling to the Organism: An Innovative Model of Dynamic Toxic Hotspots in Stream Systems." Bowling Green State University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu149019827523479.

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3

Dallas, Lorna Jane. "An ecotoxicological assessment of the impacts of chronic exposure to metals and radionuclides on marine mussels : relating genotoxicity to molecular and organism-level effects." Thesis, University of Plymouth, 2013. http://hdl.handle.net/10026.1/2850.

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Metals and radionuclides are environmentally relevant contaminants, yet their potential impacts on marine organisms have not been adequately evaluated. This is especially true for exposures of longer duration and/or lower contaminant concentration (i.e. chronic) which are often more representative of real world scenarios. In this context, a suite of biomarkers at different levels of biological organisation were investigated in an ecologically relevant bivalve species, Mytilus galloprovin- cialis after exposure to nickel (a metal), zinc pyrithione (an organometal) and tritiated water (a radionuc
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4

Сулим, Людмила Григорівна, Людмила Григорьевна Сулим, Liudmyla Hryhorivna Sulym, Віталій Зіновійович Сікора, Виталий Зиновьевич Сикора та Vitalii Zinoviiovych Sikora. "Морфоструктура паренхимы почек при общем облучении". Thesis, Издательство СумГУ, 1997. http://essuir.sumdu.edu.ua/handle/123456789/24761.

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5

Mager, Edward Michael. "Interactions Between Water Chemistry and Waterborne Lead Exposure to Freshwater Organisms." Scholarly Repository, 2010. http://scholarlyrepository.miami.edu/oa_dissertations/666.

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This dissertation characterizes the influences of water chemistry on the acute toxicity of lead (Pb) to two of the long-standing sentinel test organisms commonly employed by the United States Environmental Protection Agency (USEPA), the fathead minnow (Pimephales promelas) and daphnid (Ceriodaphnia dubia), for parameterization of an acute Pb Biotic Ligand Model (BLM). In addition, a toxicogenomic approach was employed to identify genes that might serve as molecular markers of Pb exposure and long-term effects, as well as provide new insights as to the underlying toxic mechanisms of chronic Pb
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6

Steele, Alexandra Nicole. "Reconsidering exposure: The effects of dynamic contaminant plumes on aquatic organisms." Bowling Green State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1586946141792686.

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7

Lindgren, Torsten. "Cabin Air Quality in Commercial Aircraft : Exposure, Symptoms and Signs." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3462.

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8

Ashauer, Roman. "Predicting effects of fluctuating or pulsed exposure to pesticides on aquatic organisms." Thesis, University of York, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.440836.

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9

Wenger, Michael. "Impacts of multiple stressors on fish : responses to pathogen and pollutant exposures on molecular and organism-levels /." [S.l.] : [s.n.], 2009. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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10

FUSCO, LAURA. "TOXICOLOGICAL EFFECTS OF GRAPHENE FAMILY NANOMATERIALS AFTER CUTANEOUS EXPOSURE." Doctoral thesis, Università degli Studi di Trieste, 2018. http://hdl.handle.net/11368/2918471.

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Graphene and the so-called Graphene Family Nanomaterials (GFNs) have unique physicochemical properties, making them promising candidates for a wide range of applications in several fields. However, they may pose health risks, and little is known about their potential human toxicity, so far. Skin is the largest organ of human body and the cutaneous exposure represents one of the major exposure routes to GFNs. Even though cutaneous contact to other related materials, such as graphite and carbon nanomaterials, has been associated with increased incidence of skin diseases, such as airborne irritan
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11

Remaili, Timothy Michael. "The influence of sediment bioturbation on contaminated sediment biogeochemistry, contaminant exposure and toxicity to benthic organisms: perspectives on assessment and remediation." Thesis, Griffith University, 2018. http://hdl.handle.net/10072/380991.

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The contamination and degradation of many sediment environments have been attributed to the global surge of anthropogenic activities near coastlines. Organism-sediment interactions (i.e. bioturbation) are known to alter sediment biogeochemistry and potentially increase the risk of contaminant exposure and toxicity to surrounding ecosystems. Current risk assessment frameworks for contaminated sediments seldom consider the impacts of bioturbation on contaminant exposure explicitly, leading to potentially inaccurate assessments and ineffective management strategies. In this thesis, the impacts of
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12

SACCHI, ANGELA. "ASSESSING EFFECTS TO ACQUATIC ORGANISMS OF CONTAMINANTS EXPOSURE ACROSS LEVELS OF BIOLOGICAL ORGANISATION, IN THE FRAME OF WFD 2000/60/EC." Doctoral thesis, Università Cattolica del Sacro Cuore, 2011. http://hdl.handle.net/10280/977.

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Gli ecosistemi acquatici sono il comparto ambientale finale per molti contaminanti introdotti nell’ambiente, specialmente per quelli persistenti, provenienti da diverse attività antropiche. Gli organismi acquatici sono esposti simultaneamente a differenti classi di composti chimici e, la loro fisiologia può esserne affetta anche da basse concentrazioni ambientali che ne determinano un effetto a cascata drammatico sull’intero ciclo vitale delle stesse. Per identificare gli effetti ecotossicologici si devono scegliere delle variabili di studio che sono sensibili a cambiamenti di esposizione e qu
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13

SACCHI, ANGELA. "ASSESSING EFFECTS TO ACQUATIC ORGANISMS OF CONTAMINANTS EXPOSURE ACROSS LEVELS OF BIOLOGICAL ORGANISATION, IN THE FRAME OF WFD 2000/60/EC." Doctoral thesis, Università Cattolica del Sacro Cuore, 2011. http://hdl.handle.net/10280/977.

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Gli ecosistemi acquatici sono il comparto ambientale finale per molti contaminanti introdotti nell’ambiente, specialmente per quelli persistenti, provenienti da diverse attività antropiche. Gli organismi acquatici sono esposti simultaneamente a differenti classi di composti chimici e, la loro fisiologia può esserne affetta anche da basse concentrazioni ambientali che ne determinano un effetto a cascata drammatico sull’intero ciclo vitale delle stesse. Per identificare gli effetti ecotossicologici si devono scegliere delle variabili di studio che sono sensibili a cambiamenti di esposizione e qu
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14

Figueiredo, Joana Rita Monteiro. "Toxicity of novel anti-fouling nanomaterials in Marine organismsv." Master's thesis, Universidade de Aveiro, 2017. http://hdl.handle.net/10773/22019.

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Mestrado em Ecologia Aplicada<br>Biofouling is an ecological succession of fouling communities in submerged surfaces that has extensive ecological, environmental and economic impacts worldwide when developed over man-made structures. In order to minimize this problem, biocides with anti-fouling properties are commonly used in protective coatings of submerged structures. Some decades ago, organotin compounds were used as effective anti-fouling agents, however they were completely banned in 2008 due to the toxic and biomagnification effects. As a consequence, a new generation of biocides were de
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15

Nayek, Subhayu. "Toxicological and Biochemical Changes Induced by Sub-Acute Exposure of Biological Organisms to Silver Nanoparticles Using the Soft-Landing Ion Mobility Instrument." Thesis, University of North Texas, 2020. https://digital.library.unt.edu/ark:/67531/metadc1752347/.

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In this study, we have developed a novel way of generating and exposing biological organisms (both prokaryotic and eukaryotic) to silver nanoparticles (AgNPs) and studying the biochemical changes induced by these particles. We analyzed the various organs of Wistar rats for localization and quantification of these particles using mass spectrometric and molecular biological techniques. Highest levels of AgNP was found in the lung tissue in addition to being present in the liver and kidneys. Analysis of the of the blood plasma from AgNP exposed rats revealed elevated levels of glutathione-disulfi
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16

Buisset-Goussen, Adeline. "Etude des effets multigénérationnels d'une exposition chronique aux rayonnements ionisants chez un organisme modèle : le nématode Caenorhabditis elegans." Thesis, Aix-Marseille, 2014. http://www.theses.fr/2014AIXM4077/document.

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L'évaluation de l'impact écologique d'une exposition aux rayonnements ionisants est devenue une préoccupation majeure. L'objectif de ce doctorat était d'étudier les effets multigénérationnels d'une irradiation gamma chronique selon une approche intégrée, des traits d'histoire de vie aux mécanismes subcellulaires chez un organisme modèle, le nématode Caenorhabditis elegans. L'étude des effets d'une irradiation gamma chronique sur les traits d'histoire de vie de C. elegans a d'abord été effectuée. Pour cela, trois générations ont été exposées et deux générations ont été placées en environnement
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17

Van, der Merwe Nicolene. "DNA damage and repair in nail technicians caused by occupational exposure to volatile organic compounds / N. van der Merwe." Thesis, North-West University, 2010. http://hdl.handle.net/10394/4928.

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Objectives: The aim of this study was to determine if exposure to volatile organic compounds can lead to DNA damage and impaired DNA repair capacity. Nail cosmetics is a fast growing industry around the world where employees and clients are subjected to various chemical substances which may be harmful to their health: such as formaldehyde, toluene, acetone, xylene, ethylmethacrylate, methylmethacrylate and n–buthyl acetate. These chemicals have the potential to be harmful to their health and exposure to these chemicals should be actively controlled. Formaldehyde is classified as a human carcin
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18

SAVOCA, Dario. "STUDIO DELLA BIODISTRIBUZIONE DI SOSTANZE BIOLOGICAMENTE ATTIVE IN ORGANISMI ACQUATICI." Doctoral thesis, Università degli Studi di Palermo, 2022. http://hdl.handle.net/10447/564226.

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19

Silva, Ludimila Cristina Souza. "Percepção dos trabalhadores de saúde sobre a exposição a micro-organismos multirresistentes." Universidade Federal de Goiás, 2013. http://repositorio.bc.ufg.br/tede/handle/tede/3764.

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Submitted by Erika Demachki (erikademachki@gmail.com) on 2014-12-08T15:34:04Z No. of bitstreams: 2 Dissertação - Ludimila Cristina Souza Silva - 2013.pdf: 4243225 bytes, checksum: 53237624d72058c3a60ec16adc7e23f3 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)<br>Approved for entry into archive by Erika Demachki (erikademachki@gmail.com) on 2014-12-08T15:34:37Z (GMT) No. of bitstreams: 2 Dissertação - Ludimila Cristina Souza Silva - 2013.pdf: 4243225 bytes, checksum: 53237624d72058c3a60ec16adc7e23f3 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7
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20

Philamore, Hemma. "An energetically autonomous artificial organism." Thesis, University of Bristol, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.691260.

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A key environmental concern in the 21st century is polluted water, requiring monitoring or remediation, often in locations which are hazardous, expansive, or difficult to reach. Robots capable of long term autonomous operation with the ability to tackle these environmental challenges are in great need. Microbial fuel cells (MFCs) are an emerging technology for water decontamination and electricity generation which convert biodegradable matter found in waterways, including pollutants such as algae and petrochemicals, to usable electrical power. As such MFCs present a promising, bioinspired powe
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21

Louisot, Jean-Paul. "Enterprise-wide risk management : contribution au développement d’outils permettant la mise en place d’une gestion globale et intégrée dans les organismes." Thesis, Paris 1, 2014. http://www.theses.fr/2014PA010023.

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Plutôt qu’une méthode scientifique traditionnelle, basée sur la réflexion théorique ou sur l’analyse de données empirique, la plus fréquemment rencontrée dans les départements « risques &amp;assurances » des universités américaines, et également asiatique, je me suis documenté en assistant aux principales conférences professionnelles du monde entier, Amérique du Nord, Europe et Australasie sans oublier l’Afrique au travers de l’enseignement et des conférences des assureurs.Par ailleurs l’enseignement de la qualification professionnelle d’ARM à des générations de praticiens depuis 1994 a permis
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22

Miller, Ruth. "Staphylococcus aureus : the host-organism relationship." Thesis, University of Oxford, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.555258.

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Staphylococcus aureus is a worldwide leading cause of skin and soft tissue, bone and joint, and bloodstream infection. Despite this, S. aureus is also a harmless commensal in about one third of the population, although carriage is a risk factor for subsequent disease. S. aureus has evolved resistance to several antibiotics, including meticillin, resulting in meticillin-resistant S. aureus (MRSA), which in the UK largely consists of two epidemic lineages. In spite of much research, substantial aspects of the epidemiology and biology of S. aureus are still poorly understood. In investigating the
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23

Spencer, Mark. "Peronosporomycetes : molecular phylogenies and organism evolution." Thesis, University of Reading, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.414563.

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24

Muller, Rikky 1980. "A microfabricated dielectrophoretic micro-organism concentrator." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/28393.

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Thesis (M. Eng. and S.B.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, June 2004.<br>"May 2004."<br>Includes bibliographical references (leaves 83-85).<br>This project focuses on the development of a micro-organism concentrator. Pathogen detection, particularly MEMS based detection, is often limited by sample concentration. The proposed concentrator will interface with a pathogen detector. This type of pathogen concentrator can be useful for many kinds of applications including water purification systems, medical applications and biological warf
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25

Chi, Siu-chung. "Eco-toxicity of antibiotics on aquatic organism." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43783600.

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26

Kendig, Catherine Elizabeth. "Biology and ontology : an organism-centred view." Thesis, University of Exeter, 2008. http://hdl.handle.net/10036/42121.

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In this dissertation I criticize and reconfigure the ontological framework within which discussions of the organization, ontogeny, and evolution of organic form have often been conducted. Explanations of organismal form are frequently given in terms of a force or essence that exists prior to the organism’s life in the world. Traits of organisms are products of the selective environment and the unbroken linear inheritance of genetically coded developmental programs. Homological traits share unbroken vertical inheritance from a single common ancestor. Species are the product of exclusive gene fl
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27

Chi, Siu-chung, and 池少翀. "Eco-toxicity of antibiotics on aquatic organism." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43783600.

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28

Miller, Christopher. "Establishing Cryptosporidium parvum as a model organism." Thesis, University of Kent, 2017. https://kar.kent.ac.uk/66710/.

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Cryptosporidium parvum is among the most common parasites in the known world and represents one of the leading causes of death among the immunocompromised. As an apicomplexan, C. parvum has many similarities to other globally important parasites such as Plasmodium falciparum and Toxoplasma gondii. Among these similarities are a complex life cycle and the ability to invade host cells. However, unlike most other apicomplexans, the cryptosporidia appear to have lost their namesake organelle, the apicoplast, and drastically reduced the size of their genome. For decades this caused issues in classi
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Ellithey, M. S. (Mona). "Bioactivity of marine organism-derived natural products." Thesis, University of Pretoria, 2013. http://hdl.handle.net/2263/43332.

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Background: HIV/AIDS is one of the most devastating diseases in the world with approximately 36 million people living with the virus in 2012 and approximately 2.7 million new infections in that same year. Antiretroviral therapy (ART) successfully reduce infection and decrease symptoms; but, the emergence of viral drug resistance due to drug induced mutations in viral genes can render treatment ineffective. Infection with HIV not only weakens the immune system leading to AIDS and increasing the risk of opportunistic infections, but also increases the risk of several types of cancer. These
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Feroce, Marcello. "Cros-Organism Annotation Prediction through Deep Learning Algorithms." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amslaurea.unibo.it/14244/.

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Studying how genes or proteins influence humans and other species' lives is paramount. To study that, it's necessary to know which functional properties are specific for each gene or protein. The association between one gene or protein and a functional properties is called annotation. An annotion can be 0 or 1. 1 means that gene or protein contributes to the activation of a certain functional property. Functional properties are referred by terms, which are strings that belong to ontologies. This work aim is to predict novel gene annotations for little know species such as Bos Taurus. To predic
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31

Quarfood, Marcel. "Transcendental idealism and the organism : essays on Kant." Doctoral thesis, Stockholms universitet, Filosofiska institutionen, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-273.

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The notion of the organism has a somewhat ambiguous status in Kant’s philosophy. On the one hand it belongs to natural science, on the other hand it is based on an analogy with the structure of reason. Biology therefore has a peculiar place among the sciences according to Kant: it is a natural science constituted by the use of a regulative maxim. The present study places Kant’s views on biological teleology in the larger context of transcendental idealism. It consists of five essays. The first one treats the notions of things in themselves and appearances, arguing for an interpretation in term
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Ball, J. M. "Antibiotic production and inactivation by a producing organism." Thesis, University of Southampton, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234469.

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Романюк, Оксана Костянтинівна, Оксана Константиновна Романюк, Oksana Kostiantynivna Romaniuk, S. Romanyuk, and Olamide O. Otesanya. "Smoking amond minors and their effects on organism." Thesis, Видавництво СумДУ, 2010. http://essuir.sumdu.edu.ua/handle/123456789/6668.

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34

Corris, Amanda B. "Organism-Environment Codetermination: The Biological Roots of Enactivism." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1593266129358889.

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35

Buchwitz, Brian. "Chromosome segregation in the holocentric organism C. elegans /." Thesis, Connect to this title online; UW restricted, 2004. http://hdl.handle.net/1773/4996.

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36

Davies, Nathaniel Jude. "Nasonia vitripennis : an emerging model organism for chronobiology." Thesis, University of Leicester, 2017. http://hdl.handle.net/2381/39828.

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The circadian clock co-ordinates a wide range of biological processes in animals and as such has implications for a range of research topics, including human disease. Recent research has shown that Drosophila, the most widely used insect clock model, may be somewhat esoteric, suggesting that other insects may make more suitable models. The work presented in this thesis advances the jewel wasp Nasonia vitripennis as a model for circadian research. Firstly, the response of the Nasonia circadian clock to temperature was characterised, revealing the presence of a temperature compensation mechanism
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37

Wang, Yushi Politano Marcela Weber Larry Joseph. "A multidimensional Eulerian-Lagrangian model to predict organism distribution." [Iowa City, Iowa] : University of Iowa, 2009. http://ir.uiowa.edu/etd/447.

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González, Moragas Laura. "Evaluating inorganic nanoparticles in the living organism Caenorhabditis elegans." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/400664.

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En aquesta tesi hem utilitzat el model animal Caenorhabditis elegans (C. elegans) com a sistema biològic viu per avaluar nanopartícules (NPs) per aplicacions biomèdiques. En concret, hem avaluat el comportament de dos tipus de partícules inorgàniques amb diferent mida i propietats de superfície: NPs d’òxid de ferro (SPIONs) recobertes de citrat i d’albúmina sèrica bovina (BSA), i NPs d’or recobertes de citrat de dos mides diferents (10 nm i 150 nm). Hem estudiat les interaccions nano-bio en C. elegans amb especial atenció en les propietats dels materials in vivo incloent el seu estat, ingesta,
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Beverley, Michael Charles. "Enzymology of response of an aquatic organism to xenobiotics." Thesis, University of Huddersfield, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239299.

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Kim, Young-Ju M. Arch Massachusetts Institute of Technology. "Organism of options : a design strategy for flexible space." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/42081.

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Thesis (M. Arch.)--Massachusetts Institute of Technology, Dept. of Architecture, 2008.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Includes bibliographical references (p. [83]-[86]).<br>The need for "flexibility" of architecture has been increasing as recent social demands are rapidly changing. However, many buildings designed in the name of flexibility are blocky, boring, and actually quite inflexible because of incomplete systems, or simple bad planning. A space is designed and built
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Grace, W. Mosi, S. Romanyuk, Оксана Костянтинівна Романюк, Оксана Константиновна Романюк, and Oksana Kostiantynivna Romaniuk. "Bad habits among teenagers and their effects on organism." Thesis, Видавництво СумДУ, 2009. http://essuir.sumdu.edu.ua/handle/123456789/5306.

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Романюк, Оксана Костянтинівна, Оксана Константиновна Романюк, Oksana Kostiantynivna Romaniuk, Heblo Ahmed, and Amed Ossein. "Alcogol abuse amond minors and their effects on organism." Thesis, Видавництво СумДУ, 2010. http://essuir.sumdu.edu.ua/handle/123456789/6704.

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43

Wang, Yushi. "A multidimensional Eulerian-Lagrangian model to predict organism distribution." Thesis, University of Iowa, 2009. https://ir.uiowa.edu/etd/447.

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The distribution of aquatic organism like fish eggs and snails over a river reach are crucial for research, fishing and animal protection purpose. The lack of knowledge about particle behavior close to the river bed remains a significant difficult to predict the deposit position of these particles. In this study, different boundary conditions based on bed shear stress are investigated. The 3D computational fluid dynamics (CFD) code Fluent is used for simulating the flow field.
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44

Boisvert, Catherine Anne. "The Origin of Tetrapod Limbs and Girdles: Fossil and Developmental Evidence." Doctoral thesis, Uppsala universitet, Evolutionär organismbiologi, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-98911.

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Around 375 million years ago, the first tetrapods appeared, marking one of the most important events in vertebrate evolutionary history. The fin to limb transition saw the appearance of fingers and a weight bearing pelvic girdle. While very little research has been done on the evolution of the tetrapod pelvic girdle, a fair amount has been done on the origins of fingers but some aspects remained controversial. A combination of palaeontology, developmental biology and comparative morphology was therefore used in this thesis to better understand the fin to limb transition. The pectoral fin of Pa
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Stewart, Terence John. "Molecular characterization of Sm20, a calcium binding protein of Schistosoma mansoni." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239659.

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Down, Graeme John. "Crook root disease of watercress : investigations into zoospore attraction, diagnostics, and phylogeny." Thesis, University of Bath, 2000. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323590.

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The plasmodiophorid organism, Spongospora subterranea f. sp. nasturtii, is the causal agent of crook root disease of watercress (Rorippa nasturtium-aquaticumy. The only current control measure is zinc, used such that levels do not exceed 0.07S~g mrl in effluent water. Laboratory results indicated that zinc acts by actively lysing zoospores of S. subterranea, but does not cause 100% mortality at field concentrations. At 8ug ml", around 20 % of zoospores were seen to survive compared to controls. Of other cations investigated as potential control agents, none were as effective as zinc at equival
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Naruse, Kiyoshi, Mitsuru Sakaizumi, and Akihiro Shima. "Medaka as a model organism for research in experimental biology." Laboratory of Freshwater Fish Stocks Bioscience Center Nagoya University, 1994. http://hdl.handle.net/2237/13792.

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48

Taylor-Burt, Kari. "Shiver me titin! Elucidating titin's role in organism-level performance." Thesis, Northern Arizona University, 2013. http://pqdtopen.proquest.com/#viewpdf?dispub=1543984.

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<p> The frequency of oscillatory behaviors, like shivering, depends on the animal size and the properties of the muscles driving them. Titin and other muscular proteins play an important role in determining muscle properties, such as stiffness. Because the frequency of oscillatory behaviors depends on muscle properties, we predict that changes in titin's structure would affect these behaviors. The muscular dystrophy with myositis (<i> mdm</i>) mouse model is characterized by a deletion in the N2A region of titin. Homozygous <i>mdm</i> mutants are substantially smaller (body mass is &frac12; to
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49

Temple, Graham Stuart. "Pseudomonas stutzeri : characteristics of the organism and its cell envelope." Thesis, University of Hull, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.304438.

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50

Bándi, Gergely. "Virtual living organism : a rapid prototyping tool to emulate biology." Thesis, Cranfield University, 2011. http://dspace.lib.cranfield.ac.uk/handle/1826/7230.

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Rapid prototyping tools exist in many fields of science and engineering, but are rare in biology especially not general tools that can handle the diversity and complexity of the many spatial and temporal scales in nature. In this thesis a general use, cell-based, middle-out biology emulation programming framework (outlining a programming paradigm) is presented, that enables biologists to emulate and use virtual biological systems of previously unimaginable complexity and potentially get results accurate enough to be used in research and ultimately, in clinical practice, such as diagnosis or op
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