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1

Coble, Jeffrey P., Justin L. Grobe, Alan Kim Johnson, and Curt D. Sigmund. "Mechanisms of brain renin angiotensin system-induced drinking and blood pressure: importance of the subfornical organ." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 308, no. 4 (2015): R238—R249. http://dx.doi.org/10.1152/ajpregu.00486.2014.

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It is critical for cells to maintain a homeostatic balance of water and electrolytes because disturbances can disrupt cellular function, which can lead to profound effects on the physiology of an organism. Dehydration can be classified as either intra- or extracellular, and different mechanisms have developed to restore homeostasis in response to each. Whereas the renin-angiotensin system (RAS) is important for restoring homeostasis after dehydration, the pathways mediating the responses to intra- and extracellular dehydration may differ. Thirst responses mediated through the angiotensin type
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2

Prykhodko, Olha. "STRUCTURAL CHANGES OF ORGANS AND TISSUES UNDER CONDITIONS OF DEHYDRATION DISORDERS OF WATER-SALT EXCHANGE." Clinical anatomy and operative surgery 21, no. 4 (2022): 98–106. http://dx.doi.org/10.24061/1727-0847.21.4.2022.52.

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Most processes in the body take place with the participation of water. It is an indispensable component of living organisms. Any violations of the water- electrolyte balance have consequences for the structural organization of all organs and tissues. Studying changes in the structural organization of organs and tissues during dehydration is an urgent task of both theoretical and practical medicine. The aim was to analyze and generalize data from modern scientifi c literature on structural changes in organs and tissues during dehydration. Water is involved in maintaining a normal body temperatur
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3

Huang, Ju, Fulvio Reggiori, and Daniel J. Klionsky. "The Transmembrane Domain of Acid Trehalase Mediates Ubiquitin-independent Multivesicular Body Pathway Sorting." Molecular Biology of the Cell 18, no. 7 (2007): 2511–24. http://dx.doi.org/10.1091/mbc.e06-11-0995.

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Trehalose serves as a storage source of carbon and plays important roles under various stress conditions. For example, in many organisms trehalose has a critical function in preserving membrane structure and fluidity during dehydration/rehydration. In the yeast Saccharomyces cerevisiae, trehalose accumulates in the cell when the nutrient supply is limited but is rapidly degraded when the supply of nutrients is renewed. Hydrolysis of trehalose in yeast depends on neutral trehalase and acid trehalase (Ath1). Ath1 resides and functions in the vacuole; however, it appears to catalyze the hydrolysi
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4

Pankonien, Ines, Margarida C. Quaresma, Cláudia S. Rodrigues, and Margarida D. Amaral. "CFTR, Cell Junctions and the Cytoskeleton." International Journal of Molecular Sciences 23, no. 5 (2022): 2688. http://dx.doi.org/10.3390/ijms23052688.

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The multi-organ disease cystic fibrosis (CF) is caused by mutations in the gene encoding the CF transmembrane conductance regulator (CFTR) protein, a cAMP regulated chloride (Cl−) and bicarbonate (HCO3−) ion channel expressed at the apical plasma membrane (PM) of epithelial cells. Reduced CFTR protein results in decreased Cl− secretion and excessive sodium reabsorption in epithelial cells, which consequently leads to epithelial dehydration and the accumulation of thick mucus within the affected organs, such as the lungs, pancreas, gastrointestinal (GI) tract, reproductive system and sweat glan
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5

Dunne, W. Michael. "Bacterial Adhesion: Seen Any Good Biofilms Lately?" Clinical Microbiology Reviews 15, no. 2 (2002): 155–66. http://dx.doi.org/10.1128/cmr.15.2.155-166.2002.

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SUMMARY The process of surface adhesion and biofilm development is a survival strategy employed by virtually all bacteria and refined over millions of years. This process is designed to anchor microorganisms in a nutritionally advantageous environment and to permit their escape to greener pastures when essential growth factors have been exhausted. Bacterial attachment to a surface can be divided into several distinct phases, including primary and reversible adhesion, secondary and irreversible adhesion, and biofilm formation. Each of these phases is ultimately controlled by the expression of o
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Jaikumpun, Pongsiri, Kasidid Ruksakiet, Balázs Stercz, et al. "Antibacterial Effects of Bicarbonate in Media Modified to Mimic Cystic Fibrosis Sputum." International Journal of Molecular Sciences 21, no. 22 (2020): 8614. http://dx.doi.org/10.3390/ijms21228614.

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Cystic fibrosis (CF) is a hereditary disease caused by mutations in the gene encoding an epithelial anion channel. In CF, Cl− and HCO3− hyposecretion, together with mucin hypersecretion, leads to airway dehydration and production of viscous mucus. This habitat is ideal for colonization by pathogenic bacteria. We have recently demonstrated that HCO3− inhibits the growth and biofilm formation of Pseudomonas aeruginosa and Staphylococcus aureus when tested in laboratory culture media. Using the same bacteria our aim was to investigate the effects of HCO3− in artificial sputum medium (ASM), whose
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7

Lozano-Iturbe, Víctor, Noelia Blanco-Agudín, Emma Vázquez-Espinosa, et al. "The Binding of Pseudomonas aeruginosa to Cystic Fibrosis Bronchial Epithelial Model Cells Alters the Composition of the Exosomes They Produce Compared to Healthy Control Cells." International Journal of Molecular Sciences 25, no. 2 (2024): 895. http://dx.doi.org/10.3390/ijms25020895.

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Cystic fibrosis (CF) is a genetic disease that causes dehydration of the surface of the airways, increasing lung infections, most frequently caused by Pseudomonas aeruginosa. Exosomes are nanovesicles released by cells that play an essential role in intercellular communication, although their role during bacterial infections is not well understood. In this article, we analyze the alterations in exosomes produced by healthy bronchial epithelial and cystic fibrosis cell lines caused by the interaction with P. aeruginosa. The proteomic study detected alterations in 30% of the species analyzed. In
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8

Nicolaidis, S., O. Galaverna, and C. H. Metzler. "Extracellular dehydration during pregnancy increases salt appetite of offspring." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 258, no. 1 (1990): R281—R283. http://dx.doi.org/10.1152/ajpregu.1990.258.1.r281.

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The propensity to prefer and to consume salty foods varies considerably from person to person, and excessive salt intake has been linked to a number of pathological conditions. Extracellular dehydration occurs in humans after vomiting or diarrhea and is commonly observed during pregnancy. Because the hormonal responses to extracellular dehydration are known to increase salt appetite, we tested the hypothesis that extracellular dehydration during pregnancy increases the propensity of offspring to consume salt. Pregnant rats were treated with polyethylene glycol, which is known to produce extrac
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9

Harrison, Harold E. "Dehydration in Infancy: Hospital Treatment." Pediatrics In Review 11, no. 5 (1989): 139–43. http://dx.doi.org/10.1542/pir.11.5.139.

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Dehydration of a degree severe enough to require intravenous replacement of water and electrolytes indicates (1) depletion of extracellular fluid sodium and water to such an extent that reduction of plasma volume results or (2) distortion of the composition of extracellular fluid with consequent disturbance of physiologic function. Such distortion may be marked hypernatremia, severe depletion of extracellular bicarbonate, or disturbances of potassium concentration resulting in either hyperkalemia or hypokalemia. In addition, hypocalcemia or hypomagnesemia may require specific replacement of th
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10

Tarasova, Z. G., O. K. Kirilochev, and G. R. Sagitova. "Case report of hypotonic dehydration with outcome in cerebral edema in a child." Meditsinskiy sovet = Medical Council, no. 1 (March 4, 2022): 264–67. http://dx.doi.org/10.21518/2079-701x-2022-16-1-264-267.

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Dehydration is one of the most common disorders of water and electrolyte metabolism in young children. The reasons leading to the lack of water in the child’s body are very diverse. In clinical practice, a correct assessment of the pathophysiological mechanisms in various types of dehydration is necessary, which will allow timely identification of changes in various organ systems and conduct rational rehydration therapy. Water losses in children occur in a certain sequence. First of all, the intravascular subsector of the extracellular sector is subjected to water losses (clinical manifestatio
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11

Owen, Julian A., Matthew B. Fortes, Saeed Ur Rahman, Mahdi Jibani, Neil P. Walsh, and Samuel J. Oliver. "Hydration Marker Diagnostic Accuracy to Identify Mild Intracellular and Extracellular Dehydration." International Journal of Sport Nutrition and Exercise Metabolism 29, no. 6 (2019): 604–11. http://dx.doi.org/10.1123/ijsnem.2019-0022.

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Identifying mild dehydration (≤2% of body mass) is important to prevent the negative effects of more severe dehydration on human health and performance. It is unknown whether a single hydration marker can identify both mild intracellular dehydration (ID) and extracellular dehydration (ED) with adequate diagnostic accuracy (≥0.7 receiver-operating characteristic–area under the curve [ROC-AUC]). Thus, in 15 young healthy men, the authors determined the diagnostic accuracy of 15 hydration markers after three randomized 48-hr trials; euhydration (water 36 ml·kg−1·day−1), ID caused by exercise and
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12

Kadekaro, M., J. Y. Summy-Long, S. Freeman, J. S. Harris, M. L. Terrell, and H. M. Eisenberg. "Cerebral metabolic responses and vasopressin and oxytocin secretions during progressive water deprivation in rats." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 262, no. 2 (1992): R310—R317. http://dx.doi.org/10.1152/ajpregu.1992.262.2.r310.

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Progressive water deprivation increased plasma osmolality, plasma Na+ concentration, and hematocrit in proportion to the severity of dehydration. With increases of 2% in plasma osmolality (24 h dehydration), glucose utilization increased in the supraoptic nuclei and tended to increase in the neural lobe. With further dehydration, glucose utilization also increased in the paraventricular nuclei. These increases were paralleled by depletion of vasopressin and oxytocin contents in the neural lobe and by the enhanced secretion of both hormones into plasma, with a predominant increase of vasopressi
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13

Ely, Brett R., Samuel N. Cheuvront, Robert W. Kenefick, et al. "Assessment of extracellular dehydration using saliva osmolality." European Journal of Applied Physiology 114, no. 1 (2013): 85–92. http://dx.doi.org/10.1007/s00421-013-2747-z.

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14

Sengun, Sermin, Atilla Uslu, and Salih Aydin. "Application of Multifrequency Bioelectrical Impedance Analysis Method for the Detection of Dehydration Status in Professional Divers." Medicina 48, no. 4 (2012): 29. http://dx.doi.org/10.3390/medicina48040029.

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Background and Objective. The level of dehydration has been known to be a predisposing factor for the development of decompression sickness in divers. The aim of this study was to determine the level of dehydration in divers who dove with heliox and to determine whether the source of this dehydration was intracellular and/or extracellular by means of multifrequency bioelectrical impedance analysis (MF-BIA). Material and Methods. Eleven male professional divers were enrolled in the study. In order to determine the level of dehydration, MF-BIA was carried out (at 5, 50, and 100 kHz) and capillar
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15

Proppe, D. W. "Effects of hyperosmolality and diuretics on heat-induced limb vasodilation in baboons." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 258, no. 2 (1990): R309—R317. http://dx.doi.org/10.1152/ajpregu.1990.258.2.r309.

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Dehydration attenuates the increase in limb skin blood flow elicited by environmental heating (EH). This study sought to determine which of the two primary effects of dehydration, increased body fluid osmolality or decreased body fluid volume, was primarily responsible for this cutaneous vasoconstrictor bias in baboons. Unanesthetized chronically instrumented baboons were exposed to EH while in euhydrated state, after 65-69 h of water deprivation (dehydration), after infusion of a small volume of hypertonic (20%) saline to raise plasma osmolality and sodium concentration to dehydration levels,
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16

Prykhodko, Olha, Olga Avilova, Serhii Dmytruk, Olha Yarmolenko, and Alina Ponyrko. "The thymus structural organization in severe extracellular dehydration and during readaptation." Polski Merkuriusz Lekarski 53, no. 3 (2025): 340–46. https://doi.org/10.36740/merkur202503107.

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Aim: To investigate the changes of the thymus structure under extracellular dehydration and after rehydration in model experiment. Materials and Methods: The study was conducted on 40 white male rats, divided into 4 groups of 10 animals each. 2 experimental groups were subjected to extracellular dehydration during 90 days. Following this period, one group was removed from the experiment and other one was switched to the vivarium’s standard ration for 30 days (rehydration). The control groups of animals received the vivarium’s standard ration throughout the 90 days and the 120 days respectively
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17

Stallone, J. N., and E. J. Braun. "Regulation of plasma arginine vasotocin in conscious water-deprived domestic fowl." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 250, no. 4 (1986): R658—R664. http://dx.doi.org/10.1152/ajpregu.1986.250.4.r658.

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Radioimmunoassay methods were employed to quantitatively characterize secretion of the avian antidiuretic hormone [arginine vasotocin (AVT)] by the hypothalamo-neurohypophyseal system (HNS) of the conscious domestic fowl in response to chronic dehydration. Water deprivation permitted characterization of AVT secretion in response to the combined stimuli of extracellular hyperosmolality and hypovolemia; the subsequent repletion of extracellular volume permitted separation of potential osmotic and volemic factors involved in the regulation of AVT secretion. In normally hydrated birds, plasma AVT
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18

Hahn, Robert G., Dan Drobin, Yuhong Li та Joachim Zdolsek. "Kinetics of Ringerʼs Solution in Extracellular Dehydration and Hemorrhage". SHOCK 53, № 5 (2020): 566–73. http://dx.doi.org/10.1097/shk.0000000000001422.

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19

Holliday, Malcolm A. "Extracellular fluid and its proteins: dehydration, shock, and recovery." Pediatric Nephrology 13, no. 9 (1999): 989–95. http://dx.doi.org/10.1007/s004670050741.

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20

Perillan, C., M. Costales, M. Vijande, and J. Arguelles. "In utero extracellular dehydration modifies thirst in neonatal rats." Appetite 51, no. 3 (2008): 599–603. http://dx.doi.org/10.1016/j.appet.2008.04.015.

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21

Dohnalkova, Alice C., Matthew J. Marshall, Bruce W. Arey, Kenneth H. Williams, Edgar C. Buck, and James K. Fredrickson. "Imaging Hydrated Microbial Extracellular Polymers: Comparative Analysis by Electron Microscopy." Applied and Environmental Microbiology 77, no. 4 (2010): 1254–62. http://dx.doi.org/10.1128/aem.02001-10.

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ABSTRACTMicrobe-mineral and -metal interactions represent a major intersection between the biosphere and geosphere but require high-resolution imaging and analytical tools for investigation of microscale associations. Electron microscopy has been used extensively for geomicrobial investigations, and although usedbona fide, the traditional methods of sample preparation do not preserve the native morphology of microbiological components, especially extracellular polymers. Herein, we present a direct comparative analysis of microbial interactions by conventional electron microscopy approaches wit
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22

Maliutina, N. V. "Basic principles of infusion therapy: fundamentals of fluid and electrolyte balance." Infusion & Chemotherapy, no. 3.2 (December 15, 2020): 196–98. http://dx.doi.org/10.32902/2663-0338-2020-3.2-196-198.

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Background. Infusion therapy (IT) is a method of managing the functions of the organism by influencing purposefully the morphological composition and physiological properties of blood through parenteral administration of organic and inorganic solutions. The main feature of IT is that the drug completely enters the bloodstream.
 Objective. To describe the main characteristics of fluid and electrolyte balance and the IT principles.
 Materials and methods. Analysis of the literature sources on this topic.
 Results and discussion. Fluid comprises about 60 % of the human body (in chi
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23

Cheuvront, Samuel N., and Robert W. Kenefick. "Dehydration: Physiology, Assessment, and Performance Effects." Comprehensive Physiology 4, no. 1 (2014): 257–85. https://doi.org/10.1002/j.2040-4603.2014.tb00543.x.

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AbstractThis article provides a comprehensive review of dehydration assessment and presents a unique evaluation of the dehydration and performance literature. The importance of osmolality and volume are emphasized when discussing the physiology, assessment, and performance effects of dehydration. The underappreciated physiologic distinction between a loss of hypo‐osmotic body water (intracellular dehydration) and an iso‐osmotic loss of body water (extracellular dehydration) is presented and argued as the single most essential aspect of dehydration assessment. The importance of diagnostic and b
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Seger, Rony. "Special Issue: MAPK Signaling Cascades in Human Health and Diseases." International Journal of Molecular Sciences 25, no. 20 (2024): 11226. http://dx.doi.org/10.3390/ijms252011226.

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25

Mulyani, Guntari Titik, Setyo Budhi, and Kurnia . "Identifikasi Tipe Dehidrasi dan Profil Elektrolit Mayor pada Pasien Kucing di Rumah Sakit Hewan Prof. Soeparwi dan Beberapa Klinik Hewan di Wilayah Yogyakarta." Jurnal Sain Veteriner 39, no. 3 (2021): 272. http://dx.doi.org/10.22146/jsv.69901.

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Dehydration is defined as a lack of body fluids followed by loss of electrolytes, and changes in acid-base balance. The type of dehydration is limited based on the concentration of sodium in serum at the time of dehydration. Maintenance of osmotic pressure and distribution of several compartments of body fluids are the main functions of the four major electrolytes, namely sodium (Na +), potassium (K +), chloride (Cl‾), and bicarbonate (HCO3‾). Sodium is the most cation in extracellular fluid, most potassium cation in intracellular fluid and chloride is the most anion in extracellular fluid. Th
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Kovchun, V. Yu. "Histomorphometric assessment of changes in the acinus and islets of Langerhans’ of the pancreas under conditions of general dehydration of the body." Reports of Morphology 24, no. 2 (2018): 33–37. http://dx.doi.org/10.31393/morphology-journal-2018-24(2)-05.

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Dehydration accompanies a number of pathological conditions and causes alteration of the organs and systems of an organism. Research aim: to study histomorphometric changes in pancreas under the conditions of general dehydration of an organism, to identify correlation between the studied groups. The experiment was carried out on 35 white male rats. Pancreas was stained with haematoxylin and eosin and also Van Gieson’s stain was used. The size of acini and islets of Langerhans and other parenchyma formations were assessed. The acini area of has decreased by 6.5% (р˃0.05) in comparison with the
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27

Kravtsov, A. L. "Formation of Extracellular Traps - the Effective Mechanism of Organism Protection from Pathogen." Problems of Particularly Dangerous Infections, no. 2(112) (April 20, 2012): 69–74. http://dx.doi.org/10.21055/0370-1069-2012-2(112)-69-74.

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Summarized and analyzed are modern literature data on capability of cells (neutrophils, eosinophils and labrocytes) realizing the mechanisms of innate immunity, to form extracellular traps that capture and kill pathogens by secretion of DNA and antibacterial granules content into extracellular space. The efficiency of capture and bacterial clearance is higher in extracellular traps than that in phagocytosis. The mechanism of extracellular bactericidal activity is supposed to play an important role in protection of organism from bacteria which are resistant to phagocytosis by leukocytes.
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28

Howe, Debbie. "Fluid therapy for emergent and critical cases: hypovolaemia vs dehydration." Veterinary Nurse 14, no. 10 (2023): 432–36. http://dx.doi.org/10.12968/vetn.2023.14.10.432.

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Intravenous fluid therapy is commonly used in emergent and critical patients. Water is a nutrient that is vital to the survival of patients, but one that must be replenished daily. Fluid in the body can be subdivided into intracellular and extracellular portions, with extracellular being further divided into interstitial and intravascular compartments. Fluid loss from all compartments is called dehydration – this is not immediately life threatening. Hypovolaemia is fluid loss from the intravascular compartment – this is life-threatening and requires immediate treatment. Prompt patient assessme
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29

LABBE, RONALD G., KYUNG-RYOUL LEE, and PATRICK L. PERRY. "Lack of Correlation between the Enterotoxigenicity of Clostridium perfringens Isolates and Propionic Acid Formation or Amylase Activity at 46°C." Journal of Food Protection 59, no. 11 (1996): 1227–29. http://dx.doi.org/10.4315/0362-028x-59.11.1227.

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The absence in the supernatant fluid of either extracellular amylase in cultures grown at 46°C or propionic acid has been proposed for the presumptive identification of enterotoxin-positive strains of Clostridium perfringens. However we found that propionic acid was formed by several enterotoxin-positive, as well as enterotoxin-negative, strains of this organism. In addition 4 of 13 ent+ stains produced extracellular amylase during growth at 46°C. These results indicate that neither trait can be used as a reliable indicator of the enterotoxigenicity of isolates of this organism.
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30

Mongiat, Maurizio. "Extracellular Matrix and Cancer: An Intricate Affair." International Journal of Molecular Sciences 24, no. 18 (2023): 13969. http://dx.doi.org/10.3390/ijms241813969.

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In complex multicellular eukaryotes, the extracellular matrix (ECM) is an essential component of the organism, not only providing structure to the tissues, but also granting cellular cooperation through the engagement of an intricate crosstalk between all cell types [...]
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31

Lindinger, M. I. "Determining dehydration and its compartmentation in horses at rest and with exercise: a concise review and focus on multi-frequency bioelectrical impedance analysis." Comparative Exercise Physiology 10, no. 1 (2014): 3–11. http://dx.doi.org/10.3920/cep13034.

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Multi-frequency bioelectrical impedance analysis (MFBIA) has been, and likely will increasingly be, used to rapidly and non-invasively assess the time course of volume losses and recovery in horses. Dehydration in performance horses is frequently the cause of health and performance problems, and presently used techniques for objectively quantifying optimum hydration are time consuming and challenging to perform accurately. Dehydration can take a number of different forms, with a balanced loss of water and electrolytes from both extra- and intracellular fluid compartments, or a primarily extrac
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Qiu, Jing, Charles C. T. Hindmarch, Song T. Yao, Jeffrey G. Tasker, and David Murphy. "Transcriptomic Analysis of the Osmotic and Reproductive Remodeling of the Female Rat Supraoptic Nucleus." Endocrinology 152, no. 9 (2011): 3483–91. http://dx.doi.org/10.1210/en.2011-1044.

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The supraoptic nucleus (SON) of the hypothalamus is an important integrative brain structure that coordinates responses to perturbations in water balance and regulates maternal physiology through the release of the neuropeptide hormones vasopressin and oxytocin into the circulation. Both dehydration and lactation evoke a dramatic morphological remodeling of the SON, a process known as function-related plasticity. We hypothesize that some of the changes seen in SON remodeling are mediated by differential gene expression, and have thus used microarrays to document global changes in transcript ab
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Widjajanti, S. "The effect of artificial dehydration on the survival and reproduction of Lymnaea rubiginosa." Jurnal Ilmu Ternak dan Veteriner 4, no. 1 (2014): 55–59. https://doi.org/10.14334/jitv.v4i1.137.

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The effect of artificial dehydration on snail Lymnaea rubiginosa was investigated in the laboratory by monitoring its survival and development, because as aquatic organism, this snail must be able to adapt or tolerate with the changes in its habitat. Fifty laboratory-reared L. rubiginosa with shell length between 1.0-1.5 cm (adult) were placed in each sloping earth aquarium (60x80x20 cm) which were already filled with water about 15 cm depth. Five aquaria were used in this study, and one week after being established the water from 4 aquaria was drained while one aquarium was retained with wate
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Prykhodko, O. O., and A. O. Ponyrko. "SUBMICROSCOPIC CHANGES OF THYMUS UNDER CELLULAR DEHYDRATION." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 23, no. 3 (2023): 130–37. http://dx.doi.org/10.31718/2077-1096.23.3.130.

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Lack of water is one of the most stressful conditions for the body that can lead to changes in all the organs. The importance of the functional state of lymphoid organs for the homeostasis of the whole organism determines the relevance of their thorough investigation under their exposure to various factors, including dehydration. The purpose of the study is to investigate the patterns of submicroscopic changes in the thymus parenchyma of rats under cellular dehydration. Materials and methods. The study was conducted on 45 white mature male rats. The method of electron was applied. Results: Aft
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Taylor, Kris, Loretta P. Mayer, and Catherine R. Propper. "Intra- and Extracellular Dehydration-Induced Thirst-Related Behavior in an Amphibian." Physiology & Behavior 65, no. 4-5 (1998): 717–21. http://dx.doi.org/10.1016/s0031-9384(98)00227-3.

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36

Holliday, M. A., Aaron L. Friedman, and Steven J. Wassner. "Extracellular fluid restoration in dehydration: a critique of rapid versus slow." Pediatric Nephrology 13, no. 4 (1999): 292–97. http://dx.doi.org/10.1007/s004670050611.

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37

Arries, Cade, and Patricia Ferrieri. "Mobiluncus curtisii Bacteremia: Case Study and Literature Review." Infectious Disease Reports 14, no. 1 (2022): 82–87. http://dx.doi.org/10.3390/idr14010009.

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Background: There are few reports of bacteremia caused by Mobiluncus curtisii in the literature. We present a review of the literature in addition to a case study. Method: We describe the case of an 82-year-old patient who underwent gastrointestinal surgery and subsequently presented with dehydration, nausea, and hyperkalemia secondary to diarrhea. Further clinical work included blood cultures, and the patient was started empirically on piperacillin/tazobactam. Results: After five days, the blood culture bottle showed growth of a gram-variable, curved rod-shaped organism. After culture under a
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Lorenzo, Serra-Prat, and Yébenes. "The Role of Water Homeostasis in Muscle Function and Frailty: A Review." Nutrients 11, no. 8 (2019): 1857. http://dx.doi.org/10.3390/nu11081857.

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Water, the main component of the body, is distributed in the extracellular and intracellular compartments. Water exchange between these compartments is mainly governed by osmotic pressure. Extracellular water osmolarity must remain within very narrow limits to be compatible with life. Older adults lose the thirst sensation and the ability to concentrate urine, and this favours increased extracellular osmolarity (hyperosmotic stress). This situation, in turn, leads to cell dehydration, which has severe consequences for the intracellular protein structure and function and, ultimately, results in
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Kottom, Theodore J., Julia R. Köhler, Charles F. Thomas, Gerald R. Fink, and Andrew H. Limper. "Lung Epithelial Cells and Extracellular Matrix Components Induce Expression of Pneumocystis carinii STE20, a Gene Complementing the Mating and Pseudohyphal Growth Defects of ste20 Mutant Yeast." Infection and Immunity 71, no. 11 (2003): 6463–71. http://dx.doi.org/10.1128/iai.71.11.6463-6471.2003.

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ABSTRACT Pneumocystis carinii causes severe pneumonia in immunocompromised hosts. The binding of P. carinii to alveolar epithelial cells and extracellular matrix constituents such as fibronectin and vitronectin is a central feature of infection, which initiates proliferation of the organism. Herein, we demonstrate that P. carinii binding to lung cells specifically alters the gene expression of the organism, regulating fungal growth. Subtractive hybridization was performed to isolate P. carinii genes expressed following binding to mammalian extracellular matrix constituents. P. carinii STE20 (P
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40

Degen, A. A., and M. Kam. "Body mass loss and body fluid shifts during dehydration in Dorper sheep." Journal of Agricultural Science 119, no. 3 (1992): 419–22. http://dx.doi.org/10.1017/s0021859600012260.

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SUMMARYDorper sheep are raised in extreme desert areas. Body mass loss and body fluid shifts were measured in Dorper rams denied water for 4 days and offered only wheat straw. The rams lost 16·3% body mass, 22·0% total body water volume, 35·1 % extracellular fluid volume and 41·7% plasma volume. On first drinking following dehydration, Dorpers were able to consume 19·7% of their dehydrated body mass and 100·3 % of their body mass loss. It was concluded that Dorpers can survive in harsh deserts through their ability to withstand dehydration and quickly replenish body mass losses when water beco
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41

Sachan, Nimisha, Nidhi Jain, Ashish Jain, and Arunima Bhardwaj. "Parotid Abscess a Rare Infection in Neonates." Journal of Clinical Neonatology 13, no. 4 (2024): 171–73. http://dx.doi.org/10.4103/jcn.jcn_47_24.

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Inflammation of salivary gland is rare during neonatal period. Its prevalence is reported as 3.8-14/1000 in early infancy.[1] Neonatal abscess is most commonly seen with parotid gland than submandibular gland.[2,3] Prematurity, dehydration, hot weather, prolonged orogastric feeding, maternal breast abscess being the most common predisposing factors.[4] Most common organism involved is staphylococcus aureus followed by other gram positive and gram-negative organisms and is rarely seen by anaerobic organisms.[1]
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42

Davydova, L. M. "MORPHOLOGICAL FEATURES OF THE RATS’ TONGUE UNDER EXPERIMENTAL HYPOTONIC DEHYDRATION OF THEIR ORGANISM." Bukovinian Medical Herald 21, no. 2 (82) p.2 (2017): 39–43. http://dx.doi.org/10.24061/2413-0737.xxi.2.82.2.2017.53.

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43

Kolesnyk, Yu M., and M. I. Isachenko. "Analysis of the body composition of rats with experimental diabetes mellitus type 1 and its correction." Modern medical technology 16, no. 4 (2024): 247–54. https://doi.org/10.14739/mmt.2024.4.311425.

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The aim was to determine the body composition of rats with experimental type 1 diabetes mellitus and its correction with amino acids using bioimpedance analysis. Material and methods. Diabetes mellitus was modeled by the injection of streptozotocin. On the 6th week the rats were divided into 3 subgroups: DM1-1 – without correction, DM1-2 – correction with L-arginine and DM1-3 – correction with N-acetyl-L-cysteine for 2 weeks. Body composition was determined by the Vet BIS1 impedance analyzer with a study of total water volume in the body, extracellular and intracellular fluid, fat and fat-free
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44

Bichet, Daniel G. "Vasopressin at Central Levels and Consequences of Dehydration." Annals of Nutrition and Metabolism 68, Suppl. 2 (2016): 19–23. http://dx.doi.org/10.1159/000446200.

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Disorders of water balance are a common feature of clinical practice. An understanding of the physiology and pathophysiology of central vasopressin release and perception of thirst is the key to diagnosis and management of these disorders. Mammals are osmoregulators; they have evolved mechanisms that maintain extracellular fluid osmolality near a stable value, and, in animal studies, osmoregulatory neurons express a truncated delta-N variant of the transient receptor potential vannilloid (TRPV1) channel involved in hypertonicity and thermal perception while systemic hypotonicity might be perce
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45

Rodgers, Brooke, Naila Cannes do Nascimento, Abigail Cox, Taylor W. Bailey, M. Preeti Sivasankar, and Allison J. Schaser. "Molecular changes, histopathology, and ultrasonic vocalization acoustic profiles of systemically dehydrated rats." PLOS One 20, no. 4 (2025): e0322187. https://doi.org/10.1371/journal.pone.0322187.

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Systemic hydration is known to promote optimal functioning of bodily systems—including the vocal folds. The impact of systemic dehydration on the biology of the vocal folds and the downstream effects of dehydration on voice output are not well understood. An in vivo rat model of systemic dehydration was employed to investigate vocal fold gene expression, histological changes, and acoustic changes in vocalization. Ultrasonic vocalizations (USVs) were recorded every day for 5 days (baseline), in male and female Long-Evans rats (N = 36, ages: 3–4 months) using an anticipatory reward paradigm. Nex
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46

Reid, C. R., M. Beekman, T. Latty, and A. Dussutour. "Amoeboid organism uses extracellular secretions to make smart foraging decisions." Behavioral Ecology 24, no. 4 (2013): 812–18. http://dx.doi.org/10.1093/beheco/art032.

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47

Andersson, Sofia, Gunnel Dalhammar, Carl Johan Land, and Gunaratna Kuttuva Rajarao. "Characterization of extracellular polymeric substances from denitrifying organism Comamonas denitrificans." Applied Microbiology and Biotechnology 82, no. 3 (2009): 535–43. http://dx.doi.org/10.1007/s00253-008-1817-3.

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48

Cheuvront, Samuel N., Robert W. Kenefick, Nisha Charkoudian, et al. "Preliminary Characterization of Enterade® Rehydration Kinetics Following Intra- and Extracellular Dehydration." Medicine & Science in Sports & Exercise 48 (May 2016): 166. http://dx.doi.org/10.1249/01.mss.0000485502.14665.c8.

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49

Chesterfield, S. P., H. V. Joyce, T. D. Fooks, and P. W. Wilson. "PERSPECTIVE: Strategies used by organisms to survive very cold climates ‐ student’s guide." Cryoletters 46, no. 2 (2025): 67–73. https://doi.org/10.54680/fr25210110112.

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We briefly examine how cold-hardiness in general, including freeze-tolerance, freeze-avoidance and dehydration strategies allow survival in cold climates, through the eyes of some specific insects and fish. Strategies do vary with geography and latitude, even between two types of insects living in the same area. We look at ice nucleation proteins to enhance freezing and antifreeze proteins to help avoid ice formation or, in some cases, to hinder what is known as recrystallization, as a frozen organism thaws.
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NIKINMAA, MIKKO, KIRSTI TIIHONEN, and MARITA PAAJASTE. "Adrenergic Control of Red Cell pH in Salmonid Fish: Roles of the Sodium/Proton Exchange, Jacobs-Stewart Cycle and Membrane Potential." Journal of Experimental Biology 154, no. 1 (1990): 257–71. http://dx.doi.org/10.1242/jeb.154.1.257.

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We investigated the mechanisms by which adrenergic activation of sodium/proton exchange reduces the pH gradient across the membrane of rainbow trout red cells. In untreated cells, adrenergic stimulation caused a significant increase in the proton distribution ratio ([H+]e/[H+]i) across the red cell membrane. The increase in the proton distribution ratio caused by adrenergic stimulation was inhibited by the protonophore 2,4-dinitrophenol (2,4-DNP). Thus, sodium/proton exchange displaces protons from electrochemical equilibrium. Active regulation of intracellular pH by sodium/proton exchange is
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