Relevant bibliographies by topics / Extracorporeal Membrane Oxygenation (ECMO)

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Academic literature on the topic 'Extracorporeal Membrane Oxygenation (ECMO)'

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Published: 4 June 2021
Last updated: 10 March 2023

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Journal articles on the topic "Extracorporeal Membrane Oxygenation (ECMO)"

1

DONN, STEVEN M. "Neonatal Extracorporeal Membrane Oxygenation." Pediatrics 82, no. 2 (August 1, 1988): 276–77. http://dx.doi.org/10.1542/peds.82.2.276.

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The number of centers providing extracorporeal membrane oxygenation (ECMO) therapy to newborns with intractable respiratory failure has grown dramatically. The ECMO registry now includes 37 institutions in the United States,1 and there may be additional centers offering ECMO but not participating in the registry. To date, more than 1,400 patients have been treated with ECMO with a survival rate exceeding 80%. Widespread acceptance of ECMO therapy has been accomplished despite a paucity of controlled clinical trials2 and without the benefit of long-term follow-up of survivors. Initial fervor about neonatal ECMO has stemmed from the excellent survival statistics cited by most of the earlier investigators.2-4
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Thiara, AS. "Influence of Extracorporeal Membrane Oxygenation Circuit on Nutritional Supplements." Journal of Clinical Research and Reports 3, no. 5 (March 24, 2020): 01–09. http://dx.doi.org/10.31579/2690-1919/057.

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Background The main function of extracorporeal membrane oxygenation (ECMO) is to provide systemic perfusion and gas exchange for patients with severe, acute respiratory or cardiac illness. The ECMO system consists of blood pump and a membrane oxygenator. ECMO oxygenator fibers, blood pump and tubing may bind circulating compounds such as drugs and nutritional components during ECMO support. Any loss of vital nutrients due to adsorption to the ECMO circuits may lead to further nutritional debilitation in critical ill patients. Objective The purpose of study is to analyze the amount of nutritional supplements adsorbed to the ECMO circuit under controlled ex vivo conditions Methods Six identical ECMO circuits were primed with fresh human whole blood and maintained under physiological conditions at 36°C for 24 hours. A dose of nutritional supplement calculated for a 70 kg patient was added. 150 mL volume was drawn from priming bag for control samples and kept under similar conditions. Blood samples were obtained at predetermined time points and analyzed for concentrations of vitamins, minerals, lipids, and proteins. Statistical analyses were performed using mixed models with robust standard errors, which allows for repeated samples within each setup and incomplete data. Results No significant differences were found between the ECMO circuits and controls for any of the measured variables: cobalamin, folate, vitamin A, glucose, concentration of minerals, HDL cholesterol, LDL cholesterol, total cholesterol, triglycerides, and total proteins. There was an initial decrease and then and increase in the concentration of cobalamin and folate. Vitamin A concentrations decreased in both groups over time. There was a decrease in concentration of glucose and an increased concentration of lactate dehydrogenase over time in both groups. Conclusion There were no changes in the concentrations of nutritional supplements in an ex vivo ECMO circuit compared to control samples, indicating that parenteral nutrition can be given during ECMO support. However, the time span of this study was limited, and the design made it impossible to investigate any functional and structural changes over time in nutritional supplements which lead to diminished effects through the ECMO circuit.
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Richards, Guy A., and I. Joubert. "Extracorporeal membrane oxygenation (ECMO)." Southern African Journal of Critical Care 29, no. 1 (June 18, 2013): 7. http://dx.doi.org/10.7196/sajcc.161.

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Gupta, Sandip, Arpan Chakraborty, Kunal Sarkar, Dipanjan Chatterjee, and Pranay Oza. "Primary transport on extracorporeal membrane oxygenation: Two Indian center experience." Edorium Journal of Anesthesia 7, no. 1 (August 11, 2021): 1–8. http://dx.doi.org/10.5348/100021a05sg2021ra.

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Aims: Extracorporeal membrane oxygenation (ECMO) can be a lifesaving modality for patients with severe reversible pulmonary and/or cardiac failure, but its use remains restricted to a few highly equipped referral centers. Conventional transports to an ECMO center can be hazardous. Transport teams are usually trained to transfer stable patients across hospitals. As ECMO patients are extremely sick, specially trained critical care teams to deal with all possible complications in these critically ill patients will be required. Therefore, many ECMO centers have developed transport programs with the mobile ECMO team. In this study, we aim to present a brief account of the two-center experience of ECMO transport from India. Methods: Retrospective observational study is depicting the data of two mobile ECMO teams over 4 years, where 21 patients (16–74 years) were evaluated. Analysis was done for the transport arrangements, different characteristics of ECMO retrieval patients, their outcomes, and predictors of mortality of a total of 21 patients from two different referral centers of India. As it is a retrospective observational study, hence institutional ethical committee approval was waived off. Results: The mean distance of travel was 87.24±104.5 km (range 2–250 km) and transportation was by road in all cases. About 38% (n=8/21), patients had suffered from complications during transport like hypotension, cardiac arrest. There were no deaths in connection with transportation. The overall mortality rate was 33.3% with no difference over gender, age, duration of pre-ECMO ventilation, or duration of transport. The most common indication associated with ECMO transport was H1N1 infection. Conclusion: We found that patient transfer if done with proper protocols by a prepared team with full knowledge of problem areas to a referral institution while on ECMO support seems to be safe and adds no significant risk of mortality to ECMO patients.
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Prine, Kelli Beckvermit, Kimberly Goracke, and Lori Baas Rubarth. "Extracorporeal Membrane Oxygenation in the NICU." Neonatal Network 34, no. 3 (2015): 183–88. http://dx.doi.org/10.1891/0730-0832.34.3.183.

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ABSTRACTExtracorporeal membrane oxygenation (ECMO) was developed for adults but has been used in neonates as a life-saving rescue therapy for infants with respiratory failure and/or cardiac collapse as a result of congenital diaphragmatic hernia, meconium aspiration syndrome, persistent pulmonary hypertension, or systemic sepsis. ECMO has been proven to increase the survival rate for these diseases. This article provides an overview of neonatal ECMO: the history and development of neonatal ECMO, patient selection criteria, clinical management, the ECMO circuit, weaning from ECMO, and possible complications of ECMO.
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Lister, George. "Extracorporeal Membrane Oxygenation." International Journal of Technology Assessment in Health Care 7, S1 (January 1991): 52–55. http://dx.doi.org/10.1017/s0266462300012502.

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Extracorporeal membrane oxygenation (ECMO) is a means of diverting a fraction or all of the circulation through a device that permits gas exchange across a permeable membrane. The site of removal and the site of return of blood are dictated primarily by practical considerations based on the volume of flow of blood to be diverted and whether a particular organ is to be bypassed. The prototype of extracorporeal oxygenation is heart-lung bypass, used for various types of cardiac surgery, in which the entire venous return is diverted through an oxygenator (bubble or membrane type) and returned to the aorta. Since the earliest reports of the use of ECMO in neonates, venoarterial bypass has been the preferred route, with blood drained from the right atrium and returned either to the carotid artery or to the femoral artery, although the former seems to have been used most often (2;4;11;12;14;18). In some reports, veno-venous bypass has also been accomplished with removal of blood from the right atrium and return into the umbilical or femoral vein (13;19). Gas exchange across the lung may also continue, although the ventilator rate, tidal volume, or peak inspiratory pressure are usually reduced markedly during the period of extracorporeal oxygenation. Anticoagulation is accomplished with few problems by infusion of heparin sulfate throughout the duration of the procedure. There now have been enough reports in the literature (individual cases or series of patients) to demonstrate that the procedure can be carried out with a minimum of technical difficulties in newborn infants (2;3;4;11;12;18), although the selection of “appropriate” patients reduces the morbidity and technical challenges of the procedure.
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Butt, Warwick, and Graeme MacLaren. "Extracorporeal membrane oxygenation 2016: an update." F1000Research 5 (April 26, 2016): 750. http://dx.doi.org/10.12688/f1000research.8320.1.

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The use of extracorporeal membrane oxygenation (ECMO) is an important issue for intensivists, critical care nurses, surgeons, cardiologists, and many others. There has been a continued increase in the number of centres performing ECMO. This review examines novel applications and recent trends in the use of ECMO over the last 2 years. These include ECMO to facilitate the safe use of other treatments, changing the timing of initiation, newer equipment and better biocompatibility, and the ability of ECMO programs to essentially choose which cluster of potential complications they are prepared to accept. ECMO continues to evolve, diversify in its applications, and improve in safety.
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Yu, Xindi, Yinyu Yang, Wei Zhang, Zheng Guo, Jia Shen, Zhuoming Xu, Haibo Zhang, and Wei Wang. "Postcardiotomy Extracorporeal Membrane Oxygenation in Neonates." Thoracic and Cardiovascular Surgeon 69, S 03 (July 29, 2021): e41-e47. http://dx.doi.org/10.1055/s-0041-1730034.

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Abstract Background Extracorporeal membrane oxygenation (ECMO) provides circulatory support in children with congenital heart disease, particularly in the setting of cardiopulmonary failure and inability to wean from cardiopulmonary bypass. This study summarized the clinical application of ECMO in the treatment of heart failure after cardiac surgery in neonates. Materials and Methods Clinical data of 23 neonates who received ECMO support in our center from January 2017 to June 2019 were retrospectively analyzed. Results Twenty-three neonates, aged from 0 to 25 days and weight between 2,300 and 4,500 g, with heart failure postcardiotomy were supported with ECMO. The successful weaning rate was 78.26% and discharge rate was 52.17%. Bleeding and residual malformation were the most common complications. The univariate analysis showed that nonsurvivors were related to the factors such as higher lactate value of ECMO 12 and 24 hours (p = 0.008 and 0.001, respectively), longer time to lactate normalization (p = 0.001), lactate > 10 mmol/L before ECMO (p = 0.01), lower weight (p = 0.01), longer ECMO duration (p = 0.005), lower platelet count (p = 0.001), more surgical site bleeding (p = 0.001), and surgical residual malformation (p = 0.04). Further logistic regression analysis revealed that higher lactate value of ECMO 24 hours (p = 0.003), longer ECMO duration (p = 0.015), and surgical site bleeding (p = 0.025) were independent risk factors. Conclusion ECMO was an effective technology to support the neonates with cardiopulmonary failure after open heart surgery. Control the lactate acidosis and surgical site bleeding event may be helpful for patients' recovery.
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Mehta, Chitra, and Yatin Mehta. "Nosocomial Infections in Extracorporeal Membrane Oxygenation." Journal of Cardiac Critical Care 7 (January 30, 2023): 12–16. http://dx.doi.org/10.25259/mm_jccc_302.

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Extra corporeal membrane oxygenation (ECMO) has become an important modality in ICU for treating patients with severe hemodynamic and respiratory failure. It helps clinicians gain time for the primary disease to recover with definitive treatment, and aids in cardio pulmonary recovery of the patient. Most of the patients who require ECMO support are quite sick and fragile. Nosocomial infection is second most common complication after hemorrhage in ECMO patients.It affects about two-third of patients receiving ECMO. There is a lack of sufficient knowledge in this particular area. More focused efforts should be made in future to combat nosocomial infection in ECMO patients.
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., Chandni. "A 22 Year Old Female Case Scenario: Veno-venous Extracorporeal Membrane Oxygenation." Indian Journal of Holistic Nursing 12, no. 1 (March 27, 2021): 13–16. http://dx.doi.org/10.24321/2348.2133.202103.

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ECMO (Extracorporeal membrane oxygenation) is one of the epic innovations of medical science to support the life of a human, in various conditions of lung failure, where it is difficult to maintain oxygenation of the body. ECMO was considered a very good option for conventional cardiopulmonary bypass technique and evolved into treatment of severe acute respiratory distress syndrome (ARDS) during the 1970s. Many kinds of research have been done on a similar topic. The initial reports on the utilisation of ECMO in ARDS patients were very exciting, and afterwards, ECMO proved to be certainly advantageous in infants having acute respiratory failure with a survival rate of almost 80%. There were two large randomised controlled trials, done during the period of 1979-1994 in adults with ARDS, that showed the failure of ECMO, with the survival rate range between 10% to 33%in the ECMO groups. Since then, ECMO treatment for ARDS patients has undergone further advancements by combining with lung-protective ventilation strategies and further by applying heparin-coated equipment, membranes, and tubings. Many healthcare facilities have used this advanced ECMO technology and achieved survival rates of more than 50%. However, whether improved ECMO can really challenge the advanced conventional treatment of adult ARDS is still a matter of debate and needs further studies.It was seen that acute respiratory failure requires intensive care. In few cases where ventilator support doesn’t prove effective, only the option of V-V ECMO remains. The present article describes the case of a 22-year-old female patient who was admitted with severe acute respiratory distress syndrome with associated multiple organ failure. The patient was admitted to the emergency of the Fortis Hospital with suspected acute kidney injury of unknown aetiology. After the initial 4 days of diagnostics at the ward, the patient required a further 24 days of hospital treatment and spent 16 days at the Intensive Care Unit. There, she underwent ECMO V-V therapy, lasting 14 days, which resulted initially in the improvement of his arterial blood gas parameters and clinical condition but later on, she developed pneumothorax and her condition worsened day by day gradually becoming critical.
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Dissertations / Theses on the topic "Extracorporeal Membrane Oxygenation (ECMO)"

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Wellman, Joshua. "An exploration of staff experiences of extracorporeal membrane oxygenation (ECMO)." Thesis, University of East London, 2017. http://roar.uel.ac.uk/6732/.

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Intensive care unit (ICU) staff are exposed to a broad range of professional, ethical and clinical practice issues such as when to offer and withdraw potentially life-saving care, which are most apparent when working with hyper-advanced technologies such as extracorporeal membrane oxygenation (ECMO). Despite the rapid increase in use of ECMO to support adults with critical heart and lung conditions, few studies have documented staff experiences of working with this technology. This study aimed to explore ICU doctors and nurses conceptualisations of key professional, ethical and clinical practice issues relating to ECMO, and the psychological impact of managing them. A qualitative design was utilised, in which semi-structured interviews were conducted with 10 ICU staff (five doctors and five nurses), working in a specialist ECMO centre in the United Kingdom (UK). Data were analysed using thematic analysis, underpinned by a critical realist epistemological stance. Three key themes were identified. 1) Embodying the ECMO Specialist: Staff experienced a sense of mastery when managing technical aspects of the work, but felt inept when dealing with abstract ethical issues. Specialists sought to drive forward clinical practice, and learning was considered important for developing clinical abilities. 2) Team dynamics: Staff came together as a team to address the technical, professional and ethical challenges associated with their work with ECMO, however ECMO was also described as a divisive force in the ICU. 3) Riding the Emotional Rollercoaster: Life or death outcomes were associated with intense emotions and staff reported various ways of managing them. These findings add a new dimension to the professional and ethical discussions in the academic literature and have several implications for clinical practice, which are discussed. Further research may wish to focus on more specific aspects of ECMO care, such as the processes involved in decision-making.
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Kazdan, David. "On the automated monitoring and control of extracorporeal membrane oxygenation." Case Western Reserve University School of Graduate Studies / OhioLINK, 1992. http://rave.ohiolink.edu/etdc/view?acc_num=case1060019332.

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Horan, Marie. "A pilot investigation of mild hypothermia in neonates receiving extracorporeal membrane oxygenation (ECMO)." Thesis, University of Leicester, 2007. http://hdl.handle.net/2381/29533.

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Objective: To investigate the feasibility of applying mild hypothermia in neonates receiving extracorporeal membrane oxygenation (ECMO).;Design: A prospective, non-randomised pilot study of twenty five neonates referred for ECMO. Whole body cooling was achieved by adjustment of the extracorporeal circuit water bath temperature. Five groups (N=5 per group) were each studied for the first five days of ECMO. The first group was maintained at 37°C throughout the study period. Subsequent groups were cooled to 36°C, 35°C and finally 34°C respectively for twenty four hours and the final group to 34°C for forty eight hours before being rewarmed to 37°C. Patients were carefully assessed clinically and biologically. In addition to routine laboratory tests, cytokines (IL-6 and IL-8) complement (C3a) and molecular markers of coagulation (thrombin-antithrombin III, antithrombin III and plasmin alpha 2 plasminogen) were measured.;Results: No major clinical or circuit problems were noted during cooling or rewarming. In particular there were no problems of bleeding or cardiac arrhythmias. No systematic difference was found between groups in terms of molecular markers of coagulation complement, cytokines and platelet transfusions. This could however not be tested statistically due to small group sizes.;Conclusions: This pilot study has demonstrated that the use of mild hypothermia in patients receiving ECMO is feasible and in the number of patients studied did not produce adverse effects, as indicated by the measurements undertaken.
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Papademetriou, M. D. "Multichannel near infrared spectroscopy to monitor cerebral oxygenation in infants and children supported in extracorporeal membrane oxygenation (ECMO)." Thesis, University College London (University of London), 2011. http://discovery.ucl.ac.uk/1335908/.

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Extracorporeal membrane oxygenation is a life support system for infants and children with intractable cardiorespiratory failure. The risk for developing neurological injuries in this group of patients is considerable. The causes are multifactorial and are not yet fully understood. Induction of ECMO involves ligation of the major neck vessels – common carotid artery and internal jugular vein – which may cause lateralised cerebrovascular injury. Physiologic changes such as hypoxia, hypotension and hypercarbia associated with ECMO can disrupt cerebral autoregulation. Near infrared spectroscopy (NIRS) offers the advantage of continuous non invasive means of monitoring cerebral oxygenation at the bedside. To date, NIRS systems used clinically are single or dual channel systems and do not allow evaluation of the status of cerebral circulation in the extended cerebral regions. This work involves the development of a multichannel NIRS system for use in paediatric cardiothoracic intensive care with specific application on patients supported on extracorporeal circulation. A novel flexible neonatal cap was designed and constructed to accommodate an array of sources and detectors that provide measurements of multisite cerebral oxygenation from 12 channels. Multimodal data collection (systemic and ECMO circuit parameters) simultaneous with multichannel NIRS was established to allow monitoring of multisite cerebral oxygenation and haemodynamics. A novel method of analysis, wavelet cross-correlation, was generated to study the concordance between multisite oxyhaemoglobin concentration (HbO2) and mean arterial pressure (MAP) as a means to investigate regional variations in cerebral circulation and assess cerebral autoregualtion. Group data of 6 patients showed statistically significant differences in WCC between right and left hemispheres during sequential changes in ECMO circuit blood flow. WCC between HbO2 and MAP provides a useful method to investigate the dynamics of cerebral autoregulation during ECMO. Modest manipulations of ECMO flows are associated with regional changes in cerebral autoregulation which may potentially have an important bearing on clinical outcome.
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Demarest, Caitlin T. "Prolonging the Useful Lifetime of Artificial Lungs." Research Showcase @ CMU, 2017. http://repository.cmu.edu/dissertations/870.

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Over 26 million Americans suffer from pulmonary disease, resulting in more than 150,000 deaths annually. Lung transplantation remains the only definitive treatment for many patients, but has meager survival rates and only approximately 1,700 of the 2,200 patients added to the lung transplant wait list each year are transplanted. Extracorporeal gas exchangers have been used as an alternative to mechanical ventilation in acute respiratory failure and as a bridge to transplantation in chronic respiratory failure. Current gas exchangers are limited by their high resistance and low biocompatibility that lead to patient complications and device clot formation. Therefore, there exists a dire need for improved devices that can act as destination therapy. To accomplish the goal of destination therapy, this dissertation discusses three studies that were performed to pave the way. First, I examined clot formation and failure patterns of two common clinical devices (Maquet’s CardioHelp (CH) and Quadrox (Qx)) to further our understanding of their limitations with respect to long-term support. Overall, it was demonstrated that the Qx devices fail earlier and more frequently than CH devices and result in a significantly greater reduction in platelet count, and that a four-inlet approach is beneficial. Next, I determined the optimal sweep gas nitric oxide (NO) concentration that minimizes platelet binding and activation while ensuring that blood methemoglobin (metHb) concentrations increase less than 5%. Miniature artificial lungs were attached to rabbits in a pumped veno-venous configuration and run for 4 h with NO added to the sweep gases in concentrations of 0, 100, 250, and 500 ppm (n=8 ea.). 100 ppm significantly reduced the amount of platelet consumption (p < 0.05), reduced platelet activation as measured by soluble p-selectin (p < 0.05), and had negligible increases in metHb and will thus be used in future experiments. Last, I tested the Pulmonary Assist Device (PAD) which was designed for long term use as a bridge to transplantation and destination therapy. Benchtop experiments were performed that confirmed that it meets our design and performance goals. From here, we are equipped to commence with 30-day PAD testing in sheep.
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Tarzia, Vincenzo. "Extracorporeal membrane oxygenation(ECMO) in refractory cardiogenic shock: impact of acute versus chronic etiology on outcome." Doctoral thesis, Università degli studi di Padova, 2015. http://hdl.handle.net/11577/3424162.

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Refractory cardiogenic shock (CS) is a condition that continues to have a very high mortality despite advances in medical therapy. Conventional treatment typically comprises inotrope infusions, vasopressors and intra-aortic-balloon-pump (IABP). When circulatory instability is refractory to these treatments, mechanical circulatory support represents the only hope for survival, as indicated by current guidelines. As most of these patients present with critical circulatory instability requiring urgent or emergent therapy, the chosen mechanical assistance should be rapidly and easily implanted. For this reason ExtraCorporeal Membrane Oxygenation (ECMO) represents the ideal “bridge-to-life” and increasingly it is used to keep the patient alive while the optimal therapeutic management is determined (bridge-to-decision). Management may then follow one of three courses: “bridge-to-recovery”: patient recovery, and weaning from ECMO; “bridge-to-transplant”: direct heart transplantation; “bridge-to-bridge”: placement of ventricular-assist-device or total artificial longer-term support. There have been several large reports on the use of ECMO as a mechanical support in post-cardiotomy patients but relatively few, mostly small case-series focusing on its role in primary acute cardiogenic shock outside of the post-cardiotomy setting. We present the results of our centre’s experience (Padova) in the treatment of primary acute cardiogenic shock with the PLS-Quadrox ECMO system (Maquet) as a bridge to decision. Furthermore, we evaluated the impact of etiology on patient outcomes by comparing acute primary refractory CS secondary to acute myocardial infarction (AMI), myocarditis, pulmonary embolism (PE) and post-partum cardiomyopathy (PPCM) with acute decompensation of a chronic cardiomyopathy, including dilated cardiomyopathy (DCM), ischemic cardiomyopathy (ICM) and grown-up-congenital-heart-diseases (GUCHD). We also analyzed whether duration and magnitude of support may predict weaning and survival. Materials and Methods. Between January 2009 and March 2013, we implanted a total of 249 ECMO; in this study we focused on 64 patients where peripheral ECMO was the treatment for primary cardiogenic shock. Thirty-seven cases (58%) were “acute” (Group A-PCS: mostly acute myocardial infarction, 39%), while twenty-seven (42%) had an exacerbation of “chronic” heart failure (Group C-PCS: dilated cardiomyopathy 30%, post-ischemic cardiomyopathy 9%, congenital 3%). Results. In group C-PCS, 23 patients were bridged to a LVAD (52%) or heart transplantation (33%). In group A-PCS, ECMO was used as bridge-to-transplantation in 3 patients (8%), bridge-to-bridge in 9 (24%), and bridge-to-recovery in 18 patients (49%). One patient in both groups was bridged to conventional surgery. Recovery of cardiac function was achieved only in group A-PCS (18 vs 0 pts, p=0.0001). Mean-flow during support ≤60% of the theoretical flow (BSA*2.4) was a predictor of successful weaning (p=0.02). Average duration of ECMO support was 8.9 ±9 days. Nine patients (14%) died during support; 30-day overall survival was 80% (51/64 pts); 59% of patients were discharged, in whom survival at 48 months was 90%. Better survival was observed in patients supported for 8 days or less (74% vs 36%, p=0.002). Conclusions. In “chronic” heart-failure ECMO represents a bridge to VAD or heart-transplantation, while in “acute” settings it offers a considerable chance of recovery, often representing the only required therapy.
Lo shock cardiogeno refrattario è una condizione gravata da alta mortalità nonostante i progressi nella terapia medica. Il trattamento convenzionale comprende infusione di inotropi, vasopressori, e contropulsazione aortica (intra-aortic-balloon-pump – IABP). Quando l’instabilità emodinamica è refrattaria a questi trattamenti, il supporto meccanico al circolo rappresenta la sola possibilità di sopravvivenza, come indicato dalle attuali linee guida. Tuttavia, poichè la maggior parte di questi pazienti si presenta con severa instabilità emodinamica che richiede un intervento urgente o emergente, l’assistenza meccanica scelta dovrebbe essere impiantabile in maniera rapida e semplice. Per questa ragione, l’ExtraCorporeal Membrane Oxygenation (ECMO) rappresenta l’ideale “bridge-to-life”, che sempre più viene usato per supportare le funzioni vitali in attesa che il programma terapeutico ottimale venga stabilito (bridge-to-decision). L’iter terapeutico può poi seguire tre diversi percorsi: “bridge-to-recovery”: il paziente recupera una funzione cardiocircolatoria tale da permettere lo svezzamento dall’ECMO; “bridge-to-transplant”: il paziente viene sottoposto a trapianto cardiaco; “bridge-to-bridge”: il paziente viene trattato con impianto di un’assistenza ventricolare o di un cuore artificiale totale. Sono state riportate diverse ampie casistiche sull’uso dell’ ECMO come supporto meccanico in pazienti con shock dopo intervento cardiochirurgico (“post-cardiotomy”), ma relativamente poche serie, e limitate a pochi casi, focalizzate sul ruolo dell’ECMO nello shock cardiogeno primario (non post-cardiotomico). In questo studio si presenta l’esperienza del centro di Padova nel trattamento dello shock cardiogeno primario con il sistema ECMO PLS-Quadrox (Maquet) come bridge-to-decision. In particolare, la ricerca proposta si prefigge di valutare l’impatto della differente eziologia sull'outcome dei pazienti, paragonando gli shock cardiogeni primari “acuti”, secondari ad infarto miocardico acuto, miocardite, embolia polmonare e cardiomiopatia post-partum, con scompensi acuti di cardiomiopatie “croniche”, includendo cardiomiopatie dilatative primitive, post-ischemiche, e cardiopatie congenite dell’adulto. Si è infine analizzato se la durata e l’entità del supporto possano predire la chance di sopravvivenza e di svezzamento. Materiali e metodi. Tra Gennaio 2009 e Marzo 2013, sono stati impiantati con ECMO un totale di 249 pazienti, di questi 64 erano affetti da shock cardiogeno "primario" (52 uomini e 12 donne, di 50±16 anni di età) e sono stati trattati con supporto ECMO periferico. Trentasette casi (58%) sono stati classificati come "acuti" (Gruppo A, Acuti, IMA 39%, miocardite 6%, embolia polmonare 8%, post-partum 2%), mentre i rimanenti 27 (42%) shock erano insorti in un quadro di scompenso cardiaco "cronico" (Gruppo B, Cronici, cardiomiopatia dilatativa primitiva 30%, cardiomiopatia dilatativa post-ischemica 9%, patologie congenite 3%). Risultati della ricerca. Nel gruppo con scompenso cardiaco cronico (Gruppo B), 23 pazienti sono stati trattati con impianto o di assistenza ventricolare sinistra (52%) o trapianto cardiaco ortotopico (33%). Nel gruppo con scompenso cardiaco acuto (Gruppo A), l' ECMO è stato usato come ponte a trapianto in 3 pazienti (8%), come ponte ad impianto di assistenza ventricolare sinistra in 9 pazienti (24%) e come ponte al recupero della propria funzionalità cardiaca in 18 pazienti (49%). Un solo paziente in ogni gruppo è stato trattato con chirurgia tradizionale. Il recupero della funzionalità cardiaca si è osservato solo all'interno del Gruppo A (18 vs. 0 pazienti, p=0,0001). E' stato visto che mantenere un flusso medio di supporto ≤60% del flusso teorico (BSA*2,4) costituisce un predittore positivo di svezzamento dal dispositivo (p=0,02). Globalmente, la durata media del supporto ECMO è stata di 8,9±9 giorni. Nove pazienti (14%) sono deceduti durante il supporto ECMO; la sopravvivenza globale a 30 giorni è stata dell' 80% (5/64 pazienti); il 59% dei pazienti è stato dimesso dall’ ospedale e, tra questi, la sopravvivenza a 48 mesi è stata del 90%, senza differenze significative nei due gruppi. La sopravvivenza migliore si è osservata in quei pazienti che hanno necessitato di supporto ECMO per un periodo inferiore o uguale ad 8 giorni (74% vs. 36%, P=0,002). In conclusione nei pazienti con shock cardiogeno refrattario nell'ambito di uno scompenso cardiaco cronico l'ECMO rappresenta un dispositivo-ponte verso l'impianto di assistenza ventricolare sinistra o verso trapianto cardiaco. Nei pazienti con shock refrattario dovuto ad eziologia acuta, invece, tale supporto offre sostanziali chance di recovery, costituendo spesso l'unica terapia necessaria.
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Mosier, Jarrod M., Melissa Kelsey, Yuval Raz, Kyle J. Gunnerson, Robyn Meyer, Cameron D. Hypes, Josh Malo, Sage P. Whitmore, and Daniel W. Spaite. "Extracorporeal membrane oxygenation (ECMO) for critically ill adults in the emergency department: history, current applications, and future directions." BioMed Central, 2015. http://hdl.handle.net/10150/621244.

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UA Open Access Publishing Fund
Extracorporeal membrane oxygenation (ECMO) is a mode of extracorporeal life support that augments oxygenation, ventilation and/or cardiac output via cannulae connected to a circuit that pumps blood through an oxygenator and back into the patient. ECMO has been used for decades to support cardiopulmonary disease refractory to conventional therapy. While not robust, there are promising data for the use of ECMO in acute hypoxemic respiratory failure, cardiac arrest, and cardiogenic shock and the potential indications for ECMO continue to increase. This review discusses the existing literature on the potential use of ECMO in critically ill patients within the emergency department.
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Cederlund, Albin, and Victor Duphorn. "Kopplingantalets inverkan på bodplättsaktivering i ECMO-kretsar." Thesis, KTH, Skolan för teknikvetenskap (SCI), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-276577.

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ExtraCorporeal Membran Oxygenering (framgent ECMO) är en mycket användbar behandling i situationer där patientens tillstånd är kritiskt. ECMO kan potentiellt öka chanserna att överleva avsevärt för patienter som annars skulle avlida till följd av sina hjärt- eller lungproblem. Behandlingen är dock inte helt riskfri, utan komplikationer såsom tromboembolism och invärtes blödningar är vanliga. Dessa associeras båda med rapportens huvudsakliga ämne, nämligen blodplättsaktivering. Denna företeelse är en konsekvens av den icke fysiologiska miljö som slangsystemet utgör. Trombocyter (blodplättar) som utsätts för de höga skjuvspänningar och hastigheter i kombination med långa stillestånd i stagnationspunkter, löper ökad risk att aktiveras och därmed producera ansamlingar av koagulerat blod runtom i olika delar av systemet. I den här rapporten var kopplingarna, som utgör skarvar där olika delar av systemet kopplas samman, av intresse. Simuleringarna för att analysera kopplingarna i olika konfigurationer utfördes med hjälp av ANSYS Fluent på Parallelldatorcentrums (PDC) Beskow och Tegner. Det visade sig att flera kopplingar på rad ökade residenstiden för en individuell partikel mer än vad som vore väntat ifall resultaten från lika många enskilda koppling adderades. Från detta drogs slutsatsen att ett reducerat antal kopplingar är att föredra då det bidrar till att minska den totala blodplättsaktiveringen och därmed minska risken att patienten får komplikationer.
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9

Ferretti, Silvia. "Ruolo della fisioterapia nei soggetti adulti sottoposti a ECMO (ExtraCorporeal Membrane Oxigenation) in ICU (Intensive Care Unit): una Scoping Review." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2022. http://amslaurea.unibo.it/25937/.

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È stato dimostrato che la fisioterapia è indicata ed efficace sui pazienti ricoverati in ICU (Intensive Care Unit), ma ad oggi in letteratura non si è ancora arrivati ad un accordo sulla posologia del trattamento fisioterapico in tali pazienti in trattamento con ECMO (ExtraCorporeal Membrane Oxygenation). Questo sia perché l’utilizzo di questa procedura ha avuto solo ultimamente una grande crescita, sia perché praticare fisioterapia in una ICU presenta molti limiti, dalle condizioni psicofisiche dei pazienti alla presenza di numerosi device che creano ulteriori difficoltà. L’obiettivo di questa tesi è esporre una panoramica della letteratura riguardo l’utilizzo dell’ECMO nelle ICU, ponendo particolare attenzione alla fisioterapia e agli effetti nel trattamento tempestivo di pazienti sottoposti a ECMO. Questa Scoping Review include numerose evidenze scientifiche trovate in letteratura nelle principali banche dati (PubMed, CINAHL, EMBASE, Cochrane, PEDro), selezionando sia studi primari e secondari, che linee guida, capitoli di libri ecc pubblicati negli ultimi 10 anni. In letteratura si evince che la riabilitazione fisioterapica intensiva precoce è indicata e sicura, e può portare a una dimissione del paziente più rapida con migliori outcome. Gli studi selezionati concordano sul fatto che effettuare fisioterapia durante l’ECMO è sicuro ed efficace, se inserite all’interno di un team specializzato. Alcuni hanno evidenziato una minor durata della degenza in ICU, e un miglioramento di mobilità e forza muscolare. Pochi altri hanno rilevato un’associazione tra fisioterapia ed aumento della mortalità in ICU. Nonostante la scarsa letteratura disponibile, i benefici della fisioterapia su questo tipo di pazienti sono promettenti, anche se sono necessari ulteriori studi che valutino potenziali rischi e vantaggi riguardo l’uso di questa innovativa tecnica. Keywords: ExtraCorporeal Membrane Oxygenation (ECMO), Intensive Care Unit (ICU), Physical Therapy, Rehabilitation
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Gandolfi, José Francisco. "Avaliação in vitro e ex vivo de oxigenador de membrana de baixa resistência para o uso ECMO sem auxílio de bomba." Faculdade de Medicina de São José do Rio Preto, 2006. http://bdtd.famerp.br/handle/tede/239.

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Made available in DSpace on 2016-01-26T12:51:54Z (GMT). No. of bitstreams: 1 josefranciscogandolfi_tese.pdf: 946147 bytes, checksum: 007d161afcdde952537f95c14f87bb0c (MD5) Previous issue date: 2006-03-06
Introduction: Extracorporeal pulmonary assistance has been proposed as an invasive alternative to the conventional treatment when adequate oxygenation becomes impossible by mechanical ventilation. Extracorporeal membrane oxygenation (ECMO) attained using assisted circulation may cause hemolysis, coagulation disorders, an inflammatory response and complications inherent to a high-risk high-cost procedure. The objective of this work was to evaluate the efficacy, both in vitro and ex vivo, of a low-resistance oxygenator in ECMO without assisted circulation. Material and Method: Initially, different prototypes of the low-resistance membrane oxygenator were developed to test the influence of the of inlet and outlet conditions of the blood, the area, the quantity and placement of the fibers in the oxygenation process and the removal of carbon dioxide gas (CO2). In the in vitro tests when bovine blood was utilized, the mean flow, volume of blood needed to fill the oxygenator and for priming, oxygen saturation, carbon dioxide gas exchange and the pressure gradient were measured. For the ex vivo experiments, five Santa Inês sheep, weighing between 5 and 33 kg, were used. In each animal, variations in respect to the oxygen saturation, the PO2 and the PCO2 were studied in the systemic blood at the outlet of the oxygenator and of the venous blood using oxygen flow rates of 0.5L/min, 1.0 L/min and 1.5 L/min. Results: The oxygenator had an excellent mechanical performance, which was seen by the PO2, PCO2 and oxygen saturation of the blood at the outlet of the oxygenator. From the clinical point of view, the improvement in the PO2 and oxygen saturation and the reduction in PCO2 of the systemic arterial blood (femoral artery of the sheep), were evident in the five sheep. A tendency of better results was seen when the weight was less than 10kg. Translating these relationships in terms of blood flow and total volume, the best results appeared when the blood flow in the oxygenator/volume proportion was 20% or greater, establishing this cutoff point as the ideal flow necessary for the best performance of the oxygenator. Conclusion: The in vitro and ex vivo performance tests achieved with the low-resistance membrane oxygenator used in arteriovenous extracorporeal circulation without the assistance of a propulsion pump, proved that this device is capable of providing oxygen and removing carbon dioxide from the blood in sufficient quantities to maintain the tested parameters at acceptable limits when ventilation is prejudiced.
Introdução: A assistência pulmonar extracorpórea tem sido proposta como uma alternativa invasiva ao tratamento convencional, quando a oxigenação adequada torna-se impossível pelo uso de ventilação mecânica. A oxigenação extracorpórea por membrana (ECMO) realizada com auxílio circulatório pode produzir hemólise, distúrbios da coagulação, resposta inflamatória e complicações inerentes a um procedimento de alto risco e elevado custo. O objetivo deste trabalho foi avaliar a eficácia in vitro e ex vivo de um oxigenador de baixa resistência em ECMO sem auxílio circulatório. Material e Método: Inicialmente foram desenvolvidos diferentes protótipos do oxigenador de membrana de baixa resistência para testar a influência das condições de entrada e saída do sangue, área, quantidade e disposição das fibras no processo de oxigenação e remoção de gás carbônico (CO2). Nos testes in vitro, utilizando-se sangue bovino, foram avaliados fluxo médio, volume de sangue necessário para preencher o oxigenador ou priming, saturação de oxigênio e transferência de gás carbônico e o gradiente de pressão. Nos experimentos ex vivo foram utilizados cinco carneiros da raça Santa Inês, pesando entre 5 a 33 Kg. Em cada animal foram estudadas as variações com relação à saturação de O2, PO2 e PCO2, no sangue sistêmico, na saída do oxigenador e no sangue venoso com fluxos de oxigênio no oxigenador 0,5 L/min, 1,0 e 1,5 L/min. Resultados: O oxigenador demonstrou excelente desempenho mecânico, o que pode ser verificado pelos valores de PO2, PCO2 e SatO2 do sangue na saída do oxigenador. Do ponto de vista clínico, a melhora de PO2 e SO2 e a redução de PCO2 no sangue arterial sistêmico (artéria femoral do carneiro) foram evidentes nos cinco experimentos. Foi possível observar uma tendência para melhores resultados com pesos inferiores a 10,0 kg. Traduzindo-se essas relações em termos de fluxo sanguíneo e volemia total, os melhores resultados apareceram com proporção fluxo sangüíneo no oxigenador/volemia, de 20% ou maior, podendo-se estabelecer esse limite de corte, como fluxo ideal necessário para bom desempenho do oxigenador. Conclusão: Os testes de performance in vitro e desempenho ex vivo, realizados com o oxigenador de membrana de baixa resistência ao fluxo, para uso em circulação extracopórea arteriovenosa, sem o auxílio de bomba propulsora, mostraram resultados suficientes para concluir que tais dispositivos são capazes de fornecer Oxigênio e retirar gás Carbônico do sangue em quantidades suficientes para manter tais parâmetros em níveis aceitáveis, quando a ventilação está prejudicada.
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Books on the topic "Extracorporeal Membrane Oxygenation (ECMO)"

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B, Zwischenberger Joseph, Bartlett Robert H, and Extracorporeal Life Support Organization, eds. ECMO: Extracorporeal cardiopulmonary support in critical care. 2nd ed. [Ann Arbor, Mich.?]: Extracorporeal Life Support Organization, 2000.

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B, Zwischenberger Joseph, Bartlett Robert H, and Extracorporeal Life Support Organization, eds. ECMO: Extracorporeal cardiopulmonary support in critical care. [Ann Arbor, MI]: Extracorporeal Life Support Organization, 1995.

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Harris, Samantha. A grounded theory study to explore the experiences of nurses concerning the withdrawal of extracorporeal membrane oxygenation (ECMO) treatment. Leicester: De Montfort University, 2001.

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Schmidt, Gregory A., ed. Extracorporeal Membrane Oxygenation for Adults. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-05299-6.

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M, Arensman Robert, and Cornish J. Devn, eds. Extracorporeal life support. Boston: Blackwell Scientific Publications, 1993.

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1948-, Boynton Bruce R., Carlo Waldemar A, and Jobe Alan H, eds. New therapies for neonatal respiratory failure: A physiological approach. Cambridge: Cambridge University Press, 1994.

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1958-, Duncan Brian W., ed. Mechanical support for cardiac and respiratory failure in pediatric patients. New York: M. Dekker, 2001.

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Maybauer, Marc O., ed. Extracorporeal Membrane Oxygenation. Oxford University Press, 2022. http://dx.doi.org/10.1093/med/9780197521304.001.0001.

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Extracorporeal Membrane Oxygenation—An Interdisciplinary Problem-Based Learning Approach provides an overview of the latest techniques, management strategies, and technology surrounding the clinical use of ECMO. This interdisciplinary book reviews the most common scenarios of ECMO in 62 chapters exploring the conditions and problems arising in ECMO practice. Each chapter begins with a stem case, followed by open questions to encourage critical thinking and enable the reader to follow the management strategies of the authors, who are world leaders in the field. Followed by an evidence-based discussion, each chapter concludes with multiple-choice questions for self-assessment. This book is current in its knowledge of organ systems and management and keeps pace with new ECMO technology and surgical techniques coupled with current guidelines for management. Starting with the history of ECMO to technical aspects, circuit biocompatibility and interaction with blood, drugs, and flow physics, the volume then continues into pediatric and adult sections, focusing on both respiratory and cardiovascular support, followed by a section on trauma. The volume then concludes with a section on neurologic complications and ethics, as well as rehabilitation and ambulation of ECMO patients. In addition, to reflect the current global health situation, this book includes a chapter on ECMO management in patients suffering with COVID-19 to cover the most urgent and pressing questions around ECMO during the ongoing pandemic. This is the first ECMO book on the market to utilize a problem-based learning approach and as such is an important unprecedented project on ECMO education.
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Manual of Extracorporeal Membrane Oxygenation (ECMO) in the ICU. Jaypee Brothers Medical Publishers (P) Ltd., 2014. http://dx.doi.org/10.5005/jp/books/12297.

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Baram, Michael, Nitin Puri, and Nicholas Cavarocchi. Extracorporeal Membrane Oxygenation (ECMO), an Issue of Critical Care Clinics. Elsevier - Health Sciences Division, 2017.

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Book chapters on the topic "Extracorporeal Membrane Oxygenation (ECMO)"

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Keszler, Martin. "ECMO (Extracorporeal Membrane Oxygenation)." In Textbook of Clinical Pediatrics, 257–59. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-02202-9_22.

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Cooley, Laura A., Daniel G. Bausch, Marija Stojkovic, Waldemar Hosch, Thomas Junghanss, Marija Stojkovic, Waldemar Hosch, et al. "Extracorporeal Membrane Oxygenation (ECMO)." In Encyclopedia of Intensive Care Medicine, 918. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-00418-6_1587.

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Skinner, Sean C. "Extracorporeal Membrane Oxygenation (ECMO)." In Pediatric Surgery, 307–16. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-96542-6_27.

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Butt, Warwick, Shannon Buckvold, and Georgia Brown. "Extracorporeal Membrane Oxygenation (ECMO)." In Pediatric and Congenital Cardiology, Cardiac Surgery and Intensive Care, 1–33. London: Springer London, 2020. http://dx.doi.org/10.1007/978-1-4471-4999-6_178-2.

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Eaton, Jonathan, Christopher Trosclair, and L. Keith Scott. "Modes of ECMO." In Extracorporeal Membrane Oxygenation for Adults, 81–96. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-05299-6_3.

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McCartney, Sharon L., and Sundar Krishnan. "ECMO Weaning and Decannulation." In Extracorporeal Membrane Oxygenation for Adults, 265–75. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-05299-6_15.

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Perepu, Usha S. "Antithrombotic Therapy for ECMO." In Extracorporeal Membrane Oxygenation for Adults, 159–72. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-05299-6_8.

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Wiggins, Luke, and Amy Hackmann. "Extracorporeal Membrane Oxygenation (ECMO) Cannulation." In Atlas of Critical Care Procedures, 87–94. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-78367-3_11.

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Tung, Avery, and Tae H. Song. "Venoarterial ECMO in Respiratory Failure." In Extracorporeal Membrane Oxygenation for Adults, 277–91. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-05299-6_16.

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Kuehn, Christian, and Ruslan Natanov. "ECMO as a Bridge to Lung Transplantation." In Extracorporeal Membrane Oxygenation for Adults, 205–15. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-05299-6_11.

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Conference papers on the topic "Extracorporeal Membrane Oxygenation (ECMO)"

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Custer, Chasity M., Erika Bernardo, Carolina Gazzaneo, Janaki Paskaradevan, and Brian Rissmiller. "Extracorporeal Membrane Oxygenation (ECMO) Support For Near Fatal Asthma." In AAP National Conference & Exhibition Meeting Abstracts. American Academy of Pediatrics, 2021. http://dx.doi.org/10.1542/peds.147.3_meetingabstract.433-a.

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Naqvi, A., M. Pradhan, S. Kapoor, and P. Dicpinigaitis. "Outcomes of Extracorporeal Membrane Oxygenation (ECMO) in Severe Legionella Pneumonia." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1604.

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Thanthitaweewat, Vorawut, and Thitiwat Sriprasart. "Therapeutic Bronchoscopy Under Extracorporeal Membrane Oxygenation (ECMO) Support: Case Series." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa3404.

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MEHTA, PANKAJ, SHAHZAD JOKHIO, and ROBERT J. LENOX. "Extracorporeal Membrane Oxygenation (ECMO) For Management Of Critical Tracheal Obstruction." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a3885.

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Pihera, L. Drew, Tommer R. Ender, and Matthew L. Paden. "Extracorporeal Membrane Oxygenation (ECMO) - A systems of systems engineering characterization." In 2013 8th International Conference on System of Systems Engineering (SoSE). IEEE, 2013. http://dx.doi.org/10.1109/sysose.2013.6575274.

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Dasi, Lakshmi P., Philippe Sucosky, Stephen Goldman, Mathew Paden, James Fortenberry, and Ajit P. Yoganathan. "Development of a Novel Fluid Management System for Accurate Continuous Hemofiltration in Extracorporeal Membrane Oxygenation." In ASME 2007 2nd Frontiers in Biomedical Devices Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/biomed2007-38062.

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Failure of the cardiac or respiratory system is a common problem in the pediatric and neonatal intensive care unit. When conventional management fails to improve the child’s condition, extracorporeal life support such as extracorporeal membrane oxygenation (ECMO) can serve to provide life-saving temporary heart and lung support [1]. Renal failure often complicates care of these critically ill children on ECMO, leading to accumulation of fluid and volume overload that can worsen their heart and lung disease. Restrictive fluid management has been demonstrated to improve patient outcomes in acute lung injury.
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Herrera Camino, A., N. O'Connor, H. Gu, C. Kuklinski, A. Said, J. G. Duncan, J. Blatter, and J. C. Lin. "Long-Term Pulmonary Outcomes in Pediatric Extracorporeal Membrane Oxygenation (ECMO) Survivors." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1946.

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King, C. S., M. Desai, J. Lantry, V. Khangoora, T. B. Lee, S. Amedeo, and S. D. Nathan. "Fostamatanib Therapy in Severe ARDS Requiring Extracorporeal Membrane Oxygenation (ECMO) Support." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a4296.

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Odish, M. F., S. Chicotka, C. Yi, B. Genovese, C. R. Tainter, E. Golts, T. L. Pollema, A. Meier, A. Malhotra, and R. L. Owens. "Effect of Veno-Venous Extracorporeal Membrane Oxygenation (VV-ECMO) on Vasopressor Requirements." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1590.

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Maqsood, Usman, Ali Fawzi, and Nehal Patel. "Extracorporeal membrane oxygenation (ECMO) for near fatal asthma refractory to conventional ventilation." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa361.

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Reports on the topic "Extracorporeal Membrane Oxygenation (ECMO)"

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Zerbib, Olivier, Yaniv Hadi, Daniel Kovarsky, Gal Sahaf Levin, Tamar Gottesman, Mor Darkhovsky, and Shaul Lev. Multiple Recurrent Pneumothoraces and Thoracic Drain Insertion in a Mechanically Ventilated Patient Suffering from Methadone Induced Cardiomyopathy. Science Repository, January 2023. http://dx.doi.org/10.31487/j.jcmcr.2022.01.02.

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Objective: To describe the experience of a multimodal therapeutic approach in a patient with methadone-induced dilated cardiomyopathy who developed recurrent bilateral tension pneumothorax. Setting: Department of Intensive Care. Patient: A patient with methadone-induced cardiomyopathy and severe left ventricular dysfunction who after mechanical ventilation underwent bilateral tension pneumothorax and prolonged cardiovascular resuscitation (CPR). Interventions: Cardiac Angiography, Multiple counter–shock (defibrillator dose), Multiple Thoracic Drains. Case Report: A 56-year-old man with past IV drug abuse and severe left ventricular dysfunction was transferred from the intensive cardiac care unit (ICCU) to our intensive care unit (ICU) ward due to suspected aspiration pneumonia. Multiple attempts of weaning off mechanical ventilation were unsuccessful, followed by development of septic shock. Following cardiothoracic consultation, two thoracic drains were placed. Due to repeated events of bilateral tension pneumothorax and CPR attempts, a total of seven thoracic drains were placed, permitting rapid control and improvement in the patient status. The possibility of Extracorporeal Membrane Oxygenation (ECMO) was not considered as supportive care due to methadone use and severe secondary cardiomyopathy. In the following days, control and stabilization of the patient status was obtained. Vasopressor treatment withdrawal, cessation of drainage and removal of five thoracic access points were successfully performed prior to percutaneous tracheostomy. The two remaining drains were removed later on during hospitalization. After 29 days in the ICU, the patient was discharged to a step down ward.
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lu, sijie, shilin wei, jian li, kerong zhai, and yongnan li. Extracorporeal membrane oxygenation in pregnancy and the postpartum period：A Systematic Review andMeta Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2022. http://dx.doi.org/10.37766/inplasy2022.11.0036.

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Huang, Hui-Bin, Hua Zhou, Xiang-Jun Zhang, Yuan Xu, and Bin Du. Outcomes of septic shock adult patients receiving extracorporeal membrane oxygenation: A pooled experience of 1,895 cases. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, July 2020. http://dx.doi.org/10.37766/inplasy2020.7.0040.

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Morris, Andrew M., Peter Juni, Ayodele Odutayo, Pavlos Bobos, Nisha Andany, Kali Barrett, Martin Betts, et al. Remdesivir for Hospitalized Patients with COVID-19. Ontario COVID-19 Science Advisory Table, May 2021. http://dx.doi.org/10.47326/ocsat.2021.02.27.1.0.

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Remdesivir, a direct-acting antiviral agent, may reduce mortality and progression to mechanical ventilation in moderately ill patients hospitalized with COVID-19 on supplemental low-flow oxygen. The benefits of remdesivir for critically ill patients requiring supplemental oxygen via high-flow nasal cannula or mask, or non-invasive mechanical ventilation, is uncertain. Remdesivir does not benefit and may harm critically ill patients already receiving mechanical ventilation or requiring extra-corporeal membrane oxygenation (ECMO), and it does not provide substantial benefit for hospitalized patients who do not require supplemental oxygen. Remdesivir appears to have comparable effects when used for 5 days or 10 days, and does not appear to be associated with significant adverse effects. Remdesivir is recommended in moderately ill hospitalized patients with COVID-19 requiring supplemental oxygen (Figure 1). Remdesivir may be considered for patients requiring oxygen supplementation via high-flow nasal cannula or mask, or non-invasive mechanical ventilation. It should not be used in critically ill patients on mechanical ventilation or those receiving ECMO. Remdesivir should not be used in patients who do not require supplemental oxygen.
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