Log in

Relevant bibliographies by topics / Extraction (Chemistry) Forensic toxicology / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Extraction (Chemistry) Forensic toxicology.

Dissertations / Theses on the topic 'Extraction (Chemistry) Forensic toxicology'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 32 dissertations / theses for your research on the topic 'Extraction (Chemistry) Forensic toxicology.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Peterson, Kristina L. "Advances in flow extraction techniques : applications in forensic toxicology /." Thesis, Connect to this title online; UW restricted, 1997. http://hdl.handle.net/1773/11552.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Kashkary, Loay M. T. "Development of a combined DNA and drug extraction methodology for forensic toxicology application." Thesis, University of Hull, 2014. http://hydra.hull.ac.uk/resources/hull:11661.

Full text

Abstract:

Biological samples recovered at crime scenes may contain unsuspected and valuable evidence, such as illicit drugs, in addition to nucleic acids. Deoxyribonucleic acid (DNA) analysis provides valuable information to identify a suspect or victim, as well as to exclude an innocent individual as the perpetrator of a crime. Identification of drugs can also be very informative for forensic investigation to determine whether a perpetrator committed a crime under the influence of illicit substances. In the field of forensic analysis, sample preparation for identifying both DNA and drugs of abuse repre

APA, Harvard, Vancouver, ISO, and other styles

3

Harun, Norlida. "Application of molecularly imprinted solid phase extraction, enzyme-linked immunosorbent assay and liquid chromatography tandem mass spectrometry to forensic toxicology." Thesis, University of Glasgow, 2010. http://theses.gla.ac.uk/1992/.

Full text

Abstract:

The rapid growth of ketamine and amphetamine misuse worldwide has led to the development of methods for the detection and analysis of ketamine and amphetamines in biological specimens. Most methods previously developed in forensic toxicology for the detection of ketamine and amphetamines used GC-MS. The present work developed alternative methods based on LC-MS/MS. Ketamine was chosen as the drug of interest because there are no data currently available on the extent of ketamine abuse in Malaysia even though a large amount of ketamine has been seized by the Malaysian Royal Police, while ampheta

APA, Harvard, Vancouver, ISO, and other styles

4

Pipes, Latisha C. "Detection of Illicit Drug Use in Blood: A Validation Study of Solid Phase Extraction Coupled with Liquid Chromatography and Tandem Mass Spectrometry." Bowling Green State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1587613608312474.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Ariffin, Marinah Mohd. "The application of novel extraction and analytical techniques in forensic toxicology." Thesis, University of Glasgow, 2006. http://theses.gla.ac.uk/4144/.

Full text

Abstract:

The aim of this study was to investigate new methods of analysis which might be applied to forensic toxicology problems including those resulting from pesticides, particularly the quaternary ammonium herbicide group, and from drugs, particularly the benzodiazepine group. In the first part of this study, an efficient method for the determination of quaternary ammonium (QA) compounds (pesticides and drugs) in human whole blood was developed. The second part of this study concerned the development of a novel sorbents for solid phase extraction using molecularly imprinted polymers (MIPs). The appr

APA, Harvard, Vancouver, ISO, and other styles

6

Allen, Desiree Lisa. "The applications of supercritical fluid and solid-phase extraction techniques for the recovery of drugs of abuse from biological matrices." Thesis, University of Glasgow, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249963.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Betit, Caroline. "COMPARISON OF MULTIPLE DRUG AND METABOLITE LEVELS RECOVERED FROM SKELETONIZED REMAINS FOLLOWING STANDARD PASSIVE EXTRACTION, MICROWAVE-ASSISTED EXTRACTION AND ULTRASONIC SOLVENT EXTRACTION AND GC-MS OR UPLC-DAD." Thesis, Laurentian University of Sudbury, 2014. https://zone.biblio.laurentian.ca/dspace/handle/10219/2136.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Swortwood, Madeleine Jean. "Comprehensive Forensic Toxicological Analysis of Designer Drugs." FIU Digital Commons, 2013. http://digitalcommons.fiu.edu/etd/997.

Full text

Abstract:

New designer drugs are constantly emerging onto the illicit drug market and it is often difficult to validate and maintain comprehensive analytical methods for accurate detection of these compounds. Generally, toxicology laboratories utilize a screening method, such as immunoassay, for the presumptive identification of drugs of abuse. When a positive result occurs, confirmatory methods, such as gas chromatography (GC) or liquid chromatography (LC) coupled with mass spectrometry (MS), are required for more sensitive and specific analyses. In recent years, the need to study the activities of the

APA, Harvard, Vancouver, ISO, and other styles

9

Lee, Emma-Jane. "Forensic sample analysis using supercritical fluid extraction coupled with solid phase microextraction." Thesis, University of South Wales, 2007. https://pure.southwales.ac.uk/en/studentthesis/forensic-sample-analysis-using-supercritical-fluid-extraction-coupled-with-solid-phase-microextraction(0159ef22-bb14-433f-a50f-2bd2773ef937).html.

Full text

Abstract:

A third of adults in the UK admit to using controlled substances at least once hi their lives and the most commonly abused drug was found to be cannabis, followed by the opiates and ecognine derivatives. Forensic laboratories are continually trying to reduce the turnaround time for samples submitted for analysis, to less than the current time of four days. One of the main aims of this work was to reduce the time taken to prepare, extract and analyse hair for target analytes. A new method combining supercritical fluid extraction and solid phase micro-extraction (SFE/SPME) is introduced. This co

APA, Harvard, Vancouver, ISO, and other styles

10

Rafael, Venson. "Hollow-fibre liquid-phase microextraction : investigation into the potential use in clinical and forensic toxicology." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8697/.

Full text

Abstract:

Hollow-fibre liquid-phase microextraction (HF-LPME) was introduced in 1999 as a miniaturised version of liquid-liquid extraction (LLE) in order to reduce the consumption of organic solvents and offer an environmentally-friendly approach to extraction procedures. Since then, several studies have been published in the field of forensic and clinical toxicology applying the technique to a broad range of analytes; however more studies are necessary regarding its applicability to bioanalyses. The principle of HF-LPME is the extraction of analytes across a thin supported liquid membrane within the wa

APA, Harvard, Vancouver, ISO, and other styles

11

Connon, Catherine Cupples. "Improving Processing Efficiency for Forensic DNA Samples." Thesis, University of North Texas, 2015. https://digital.library.unt.edu/ark:/67531/metadc799515/.

Full text

Abstract:

The goal of this project was to reduce processing time for forensic DNA testing without incurring significant added costs and/or the need for new instrumentation, while still generating high quality profiles. This was accomplished by: 1) extraction normalization using the ChargeSwitch® Forensic DNA Purification Kit such that a small range of DNA concentrations was consistently obtained, eliminating the need for sample quantification and dilution; 2) developing fast PCR protocols for STR primer sets using shorter amplification methods, low volume reactions and non-fast thermal cyclers; and 3) d

APA, Harvard, Vancouver, ISO, and other styles

12

Barnard, Bernardus Francis. "The synthesis of selective immobilized ligands for the extraction of toxic metal ions from water doped with these contaminants." Thesis, Stellenbosch : Stellenbosch University, 2014. http://hdl.handle.net/10019.1/95964.

Full text

Abstract:

Thesis (PhD)--Stellenbosch University, 2014.<br>ENGLISH ABSTRACT: In this study, two novel ligands were synthesized and separately two crown ether derivatives were all immobilized onto four different silica substrates. These immobilized ligand systems were used to extract six different metal and metalloid ions in water. The extraction capacity of the different immobilized ligands was compared with each other to determine whether the substrates had any influence on the extraction capabilities of these ligands. After the extraction experiments, recovery of the immobilized ligands was attempted b

APA, Harvard, Vancouver, ISO, and other styles

13

Eckberg, Melanie N. "Forensic Toxicological Screening and Confirmation of 800+ Novel Psychoactive Substances by LC-QTOF-MS and 2D-LC Analysis." FIU Digital Commons, 2018. https://digitalcommons.fiu.edu/etd/3923.

Full text

Abstract:

Novel psychoactive substances (NPS) represent a great challenge to toxicologists due to the ability of illicit drug manufacturers to alter NPS chemical structures quickly and with ease to circumvent legislation regulating their use. Each time a new structure is introduced, there is a possibility that it has not been previously recorded in law enforcement or scientific databases. Many toxicology laboratories use targeted analytical methods that rely on libraries of known compounds to identify drugs in samples. However, these libraries do not include large numbers of NPS which could result in no

APA, Harvard, Vancouver, ISO, and other styles

14

Casper, Brent. "DEVELOPMENT OF AN EXTRACTION METHOD FOR THE MASS SPECTRAL ANALYSIS OF ORGANIC GUNSHOT RESIDUE FROM CLOTHING." UKnowledge, 2015. http://uknowledge.uky.edu/chemistry_etds/48.

Full text

Abstract:

This dissertation will focus on the extraction of volatile organic compounds associated with gunshot residue from articles of clothing, followed by analysis with mass spectrometry. During the discharge of a weapon, a cloud of volatile organic gunshot residue (OGSR) is dispersed around a firearm. This will create a high probability of transfer between the OGSR and the clothing of individuals who are near a discharged weapon. The first part of this dissertation will be the development of a method for removal of volatile OGSR from articles of clothing. Extraction of OGSR will be completed by soli

APA, Harvard, Vancouver, ISO, and other styles

15

Paul, Richard. "New developments in analytical toxicology for the investigation of drug facilitated crime." Thesis, University of South Wales, 2007. https://pure.southwales.ac.uk/en/studentthesis/new-developments-in-analytical-toxicology-for-the-investigation-of-drug-facilitated-crime(c2b2b4e3-b8c5-471f-bf3b-daca545d4afa).html.

Full text

Abstract:

Drug facilitated assault (DFA) is an increasing problem in the UK. The crime often occurs through the surreptitious administration of a drug into a victims drink, rendering the victim unable to resist the assault. The detection of these drugs in a biological specimen from the victim is one of the most challenging facets of forensic chemistry. Drug concentrations can be very low, as often only a single dose is administered, and the pharmacodynamics of commonly employed drugs further hinders the testing process. The research presented in this work shows the development of several new assays for

APA, Harvard, Vancouver, ISO, and other styles

16

Martinez, Vanessa. "The Optimization of Pressure Cycling Technology (PCT) for Differential Extraction of Sexual Assault Casework." FIU Digital Commons, 2016. http://digitalcommons.fiu.edu/etd/2999.

Full text

Abstract:

A two-step protocol has been devised as a rapid and selective alternative to conventional differential extraction techniques with an increased recovery of DNA. The protocol involves pressure cycling with the Barocycler® NEP 2320 from Pressure Biosciences. Inc. in alkaline conditions for epithelial cell lysis and removal. This step is followed by alkaline lysis at 95º C for extraction of sperm cell DNA. At 1:1 or 2:1 female to male cell ratios, high selectivity and complete separation can be achieved. But at higher ratios, male allelic dropout is observed. This protocol has been modified to gen

APA, Harvard, Vancouver, ISO, and other styles

17

Gangula, Srilatha. "Degradation of Chlorophenols in Swine Waste." TopSCHOLAR®, 2010. http://digitalcommons.wku.edu/theses/151.

Full text

Abstract:

Naturally occurring plant derived phenols can be degraded through bacteria in swine waste. Chlorinated phenols, which are not naturally present in the environment, are toxic and generated from industrial activities as such petrochemical, pharmaceutical, plastic, rubber, pesticide, iron, steel, paper production, coal conversion, wood preserving, and cellulose bleaching. Large scale coal gasification and carbonization plants are another source of chlorinated phenols. Although not normally present in the environment, chlorinated phenols are structurally similar to many plant derived phenolics. It

APA, Harvard, Vancouver, ISO, and other styles

18

Parker, Charly. "The relative recoverability of DNA and RNA profiles from forensically relevant body fluid stains." Master's thesis, University of Central Florida, 2011. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/5005.

Full text

Abstract:

Biological material (fluids or tissues) whether from the victim or suspect is often collected as forensic evidence, and methods to obtain and analyze the DNA found in that material have been well established. The type of body fluid (i.e. blood, saliva, semen, vaginal secretions, and menstrual blood) from which the DNA originated is also of interest, and messenger RNA typing provides a specific and sensitive means of body fluid identification. In order for mRNA profiling to be utilized in routine forensic casework, RNA of sufficient quantity and quality must be obtained from biological fluid st

APA, Harvard, Vancouver, ISO, and other styles

19

Colόn, Crespo Lauren J. "Determination of Human Scent Biomarkers for Race, Ethnicity and Gender." FIU Digital Commons, 2016. http://digitalcommons.fiu.edu/etd/2442.

Full text

Abstract:

Human scent has been the focal point of diverse scientific interests and research initiatives for the past several years. The knowledge gained about its composition has favored the advancement of multiple disciplines, and promoted the development of a wide variety of applications. Among these applications is the use of human scent as a resource for Forensic investigations, where scent profiles are often used as evidence to associate individuals to the scene of a crime. The characteristic nature of individual human scent has enabled this type of evidence to be used as a biometric tool for the d

APA, Harvard, Vancouver, ISO, and other styles

20

Sun, Xiaobo. "Forensic Applications of Gas Chromatography/Mass Spectrometry, High Performance Liquid Chromatography--Mass Spectrometry and Desorption Electrospray Ionization Mass Spectrometry with Chemometric Analysis." Ohio University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1329517616.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Bunch, Nathan. "Oral Fluid Method Validation for Bowling Green State University." Bowling Green State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1586969951770212.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Leufroy, Axelle. "Spéciation de l'arsenic dans les produits de la pêche par couplage HPLC/ICP-MS. Estimation de sa bioaccessibilité en ligne et applications à d'autres éléments traces métalliques d'intérêt." Phd thesis, AgroParisTech, 2012. http://pastel.archives-ouvertes.fr/pastel-00770330.

Full text

Abstract:

L'arsenic est un élément présent dans tous les compartiments de l'environnement, et les produits de la pêche représentent une source majeure d'exposition à l'arsenic par le biais de l'alimentation. Même s'il n'existe pas à ce jour de législation sur les teneurs en arsenic dans les aliments en France, les agences gouvernementales évaluent généralement les risques liés à la présence d'arsenic dans les produits de la pêche en se basant essentiellement sur la concentration totale de l'élément, sans tenir compte des différentes espèces présentes ni de leur bioaccessibilité. Par conséquent, le dével

APA, Harvard, Vancouver, ISO, and other styles

23

Costa, Judy. "The prevalence of synthetic cannabinoids in forensic casework based on data from the Drug Enforcement Administration's National Forensic Laboratory Information System." Thesis, 2015. https://hdl.handle.net/2144/13967.

Full text

Abstract:

"Synthetic Cannabinoids are among newly synthetized drugs that have become widely known throughout the United States and around the world. Originally, these compounds were used by researchers to isolate the medicinal effects of natural cannabis. Ultimately these compounds found their way into the illicit drug market as an alternative to marijuana. Unfortunately, the pharmacology of synthetic cannabinoids is not known in detail but it has been confirmed that they elicit stronger, more often times negative effects compared to natural cannabis. The use of these compounds have resulted in cases o

APA, Harvard, Vancouver, ISO, and other styles

24

Karanth, Neesha Claire. "Analysis of ketamine and xylazine in fur and bones using multidimensional liquid chromatography tandem mass spectrometry." Thesis, 2019. https://hdl.handle.net/2144/34874.

Full text

Abstract:

While ketamine is traditionally administered for anesthesia or pain management, illicit usage is often seen in forensic cases either as a recreational drug or as a tool in drug-facilitated sexual assault. Xylazine is an anesthetic agent used in veterinary medicine and does not have FDA approval for use in humans. However, it has recently been observed as a cutting agent in heroin. Post-mortem specimens present many challenges when it comes to toxicological analysis. Due to compound degradation and decomposition factors, analytes present at trace levels may be missed in blood and urine. Hair, b

APA, Harvard, Vancouver, ISO, and other styles

25

Chan, Chi Hin. "Validation and comparison of three sample preparation techniques for quantitation of amobarbital, butalbital and phenobarbital in blood and urine using UFLC-MS/MS." Thesis, 2019. https://hdl.handle.net/2144/38610.

Full text

Abstract:

This research study successfully completed three objectives: 1) validate liquid-liquid, supported-liquid, and solid-phase extractions for the quantitation of three barbiturates (amobarbital, butalbital, and phenobarbital) in blood and urine using liquid chromatography-tandem mass spectrometry; 2) to compare the efficiency and effectiveness among methods in accomplishing extraction of barbiturates under the laboratory setting at Boston University School of Medicine; and 3) to report all the analytical data to RTI International for interlaboratory comparison. For the validation study, a six-po

APA, Harvard, Vancouver, ISO, and other styles

26

McGowan, Courtney K. "Comparison of sample preparation techniques on twenty-three drugs in human whole blood and urine." Thesis, 2019. https://hdl.handle.net/2144/38672.

Full text

Abstract:

In forensic toxicology, analysis of drugs and metabolites in biological fluids is performed to determine cause of death, suspected drug use, drug facilitated sexual assaults, or whether someone was driving under the influence. Analyte identification and concentration determination can be determined in a variety of matrices (e.g., blood, urine, or oral fluid) and can be complex. It is therefore necessary to have optimal sample preparation and instrumental conditions that work for all matrices of interests. Determining the best approach can be challenging due to the amount of time and resources

APA, Harvard, Vancouver, ISO, and other styles

27

Steenkamp, P. A. "Chemical analysis of medicinal and poisonous plants of forensic importance in South Africa." Thesis, 2005. http://hdl.handle.net/10210/425.

Full text

Abstract:

The Forensic Chemistry Laboratory of Johannesburg (FCL JHB) is tasked with the chemical analysis of a variety of samples to assist in determining the cause of death where unnatural cause is suspected. Some of the samples submitted to the laboratory have a herbal or muti connotation, but a large portion of these cases turn out to have no herbal components present as only pharmaceutical or agricultural products are detected in these samples. This study combined, for the first time, forensic investigation, chemistry and botany to create a unique platform needed for the identification of poisonous

APA, Harvard, Vancouver, ISO, and other styles

28

Phung, Erika Dang. "Evaluation of the long-term stability of select phenylacetylindole, cycloalkylindole, quinolinyl, and carboxamide synthetic cannabinoids using LC-MS/MS." Thesis, 2019. https://hdl.handle.net/2144/38697.

Full text

Abstract:

Despite efforts to control synthetic cannabinoids, clandestine manufacturers continue to modify their structures to avoid legal consequences, creating an ever-changing analytical target for forensic laboratories (1). Forensic toxicology laboratories often lack the needed resources or do not have the capabilities to test for these compounds and metabolites, requiring specimens to be submitted to reference laboratories (2). Drug stability can be affected by long storage times, temperature and preservatives (3). Although these factors can be controlled, systematic research is necessary to identif

APA, Harvard, Vancouver, ISO, and other styles

29

Millard, Rebecca Elizabeth. "Optimization of extraction methodologies for condom lubricants and additives in the presence of biological fluids." Thesis, 2020. https://hdl.handle.net/2144/41303.

Full text

Abstract:

Over time, criminals have become more aware of the different types of trace evidence that are capable of being identified by forensic analysis. As a result, the frequency of actions taken to prevent the transmission of evidence, specifically biological fluids and subsequent DNA evidence, with the usage of condoms in the commission of sexual assaults, has increased. With the increased use of condoms, comes the increased awareness and probative nature of forensic analysis of the potentially unique chemical profiles residues may leave behind. This includes the identification of lubricant type

APA, Harvard, Vancouver, ISO, and other styles

30

Turner, Dee Ann. "Monitoring, characterizing, and preventing microbial degradation of ignitable liquids on soil." Thesis, 2013. http://hdl.handle.net/1805/5046.

Full text

Abstract:

Indiana University-Purdue University Indianapolis (IUPUI)<br>Organic-rich substrates such as soil provide an excellent carbon source for bacteria. However, hydrocarbons such as those found in various ignitable liquids can also serve as a source of carbon to support bacterial growth. This is problematic for fire debris analysis as samples may be stored at room temperature for extended periods before they are analyzed due to case backlog. As a result, selective loss of key components due to bacterial metabolism can make identifying and classifying ignitable liquid residues by their chemical comp

APA, Harvard, Vancouver, ISO, and other styles

31

(11178123), Chau Bao Nguyen. "Paper Spray - Mass Spectrometry: Investigation of Sampling Devices for Illicit Drug Detection and Quantification." Thesis, 2021.

Find full text

Abstract:

Different sampling devices for paper spray - mass spectrometry (PS - MS) were investigated to improve the assay’s simplicity and sensitivity over traditional approaches. In the first one, pressure-sensitive adhesive paper was used as both sampling tool to collect drug residues on surfaces and paper substrate in PS - MS analysis. This method showed a significant improvement in drug collection on surfaces leading to low nano-gram level detection limits. Other sampling device being investigated was snap-in solid-phase extraction column, which demonstrated the ability to detect trace amounts of dr

APA, Harvard, Vancouver, ISO, and other styles

32

Rainey, Christina. "Identification of Tobacco-Related Compounds in Tobacco Products and Human Hair." Thesis, 2014. http://hdl.handle.net/1805/4979.

Full text

Abstract:

Indiana University-Purdue University Indianapolis (IUPUI)<br>Analyses of tobacco products and their usage are well-researched and have implications in analytical chemistry, forensic science, toxicology, and medicine. As such, analytical methods must be developed to extract compounds of interest from tobacco products and biological specimens in order to determine tobacco exposure. In 2009, R.J. Reynolds Tobacco Co. released a line of dissolvable tobacco products that are marketed as a smoking alternative. The dissolvables were extracted and prepared by ultrasonic extractions, derivatization, a

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!