Relevant bibliographies by topics / Extrapulmonary Tumor / Journal articles

To see the other types of publications on this topic, follow the link: Extrapulmonary Tumor.

Journal articles on the topic 'Extrapulmonary Tumor'

Author: Grafiati

Published: 5 June 2025

Last updated: 15 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Extrapulmonary Tumor.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

Sedat Demircan, I. Cüneyt Kurul, A. "Intrathoracic Extrapulmonary Tumor Mass: Hemangiopericytoma." Scandinavian Cardiovascular Journal 35, no. 1 (2001): 58–60. http://dx.doi.org/10.1080/140174301750101564.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Biagi, Gianni, Giuseppe Gotti, Maurizio Di Bisceglie, Letizia Lorenzini, Michele Toscano, and Vincenzo Sforza. "Uncommon intrathoracic extrapulmonary tumor: Primary hemangiopericytoma." Annals of Thoracic Surgery 49, no. 6 (1990): 998–99. http://dx.doi.org/10.1016/0003-4975(90)90888-d.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Kim, Daeyeon, Sangjun Kim, Min Gyoung Pak, and Woo Yong Bae. "A Case of Small Cell Carcinoma Originated from Sphenoid Sinus in Patient with Recurrent Pituitary Tumor." Journal of Rhinology 28, no. 2 (2021): 110–15. http://dx.doi.org/10.18787/jr.2021.00351.

Full text

Abstract:

Small cell carcinoma (SmCC) is a type of neuroendocrine tumor commonly originating in the lung, with only about 2-4% of cases arising at extrapulmonary sites. Extrapulmonary SmCC of the head and neck has a poor prognosis and a high rate of distant metastasis. The paranasal sinus is a rare location for extrapulmonary SmCC and only a few related papers have been published to date. We report a rare case of SmCC originating from the sphenoid sinus in a patient with a recurrent pituitary tumor with a literature review.

APA, Harvard, Vancouver, ISO, and other styles

Tameron, Ashley M., and Scott R. Kelley. "Malignant Transformation of an Extrapulmonary Inflammatory Myofibroblastic Tumor." American Surgeon 82, no. 12 (2016): 361–62. http://dx.doi.org/10.1177/000313481608201212.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Morotti, Raffaella A., Michael D. Legman, Nanda Kerkar, Bruce R. Pawel, Warren G. Sanger, and Cheryl M. Coffin. "Pediatric Inflammatory Myofibroblastic Tumor with Late Metastasis to the Lung: Case Report and Review of the Literature." Pediatric and Developmental Pathology 8, no. 2 (2005): 224–29. http://dx.doi.org/10.1007/s10024-004-8088-5.

Full text

Abstract:

Inflammatory myofibroblastic tumors (IMTs) are challenging lesions with respect to classification, differential diagnosis, and biologic potential. In children, extrapulmonary IMTs, particularly those from the abdomen or mesentery, are generally aggressive, with frequent local recurrences. There are few documented patients with distant metastasis, and most of these had metastases at presentation or developed metastases within months to a few years. We add to the short list of metastatic extrapulmonary IMTs a pediatric patient in whom the primary lesion was widespread in the abdomen at presentation and metastatic disease to the lung was diagnosed 9 years after the primary resection. We describe the clinical and pathologic features of this patient and review the characteristics of extrapulmonary IMTs with distant metastasis reported in the literature.

APA, Harvard, Vancouver, ISO, and other styles

Asano, Naofumi, Michiro Susa, Seiichi Hosaka, et al. "Metastatic Patterns of Myxoid/Round Cell Liposarcoma: A Review of a 25-Year Experience." Sarcoma 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/345161.

Full text

Abstract:

Myxoid/round cell liposarcoma (MRCL), unlike other soft tissue sarcomas, has been associated with unusual pattern of metastasis to extrapulmonary sites. In an attempt to elucidate the clinical features of MRCL with metastatic lesions, 58 cases, from the medical database of Keio University Hospital were used for the evaluation. 47 patients (81%) had no metastases, whereas 11 patients (11%) had metastases during their clinical course. Among the 11 patients with metastatic lesions, 8 patients (73%) had extrapulmonary metastases and 3 patients (27%) had pulmonary metastases. Patients were further divided into three groups; without metastasis, with extrapulmonary metastasis, and with pulmonary metastasis. When the metastatic patterns were stratified according to tumor size, there was statistical significance between the three groups (P=0.028). The 8 cases with extrapulmonary metastases were all larger than 10 cm. Similarly, histological grading had a significant impact on metastatic patterns (P=0.027). 3 cases with pulmonary metastatic lesions were all diagnosed as high grade. In conclusion, large size and low histological grade were significantly associated with extrapulmonary metastasis.

APA, Harvard, Vancouver, ISO, and other styles

Asghar Nawaz, Muhammad, and Michael Shackcloth. "Unusual endobronchial prostatic metastatic tumor occluding right main bronchus." Asian Cardiovascular and Thoracic Annals 27, no. 3 (2019): 228–30. http://dx.doi.org/10.1177/0218492319827668.

Full text

Abstract:

Endobronchial metastasis from extrapulmonary solid tumors is rare, and endobronchial metastasis from the prostate is even more unusual. An 80-year-old patient presented with significant dyspnea secondary to metastatic stromal cell sarcoma of the prostate, which occluded the right main bronchus. The tumor, causing complete collapse of the right lung, was found on computed tomography and confirmed by bronchoscopy. We successfully excised the lesion using cryotherapy, with immediate resolution of symptoms and radiological lung reexpansion.

APA, Harvard, Vancouver, ISO, and other styles

Thar, Yu Yu, Poras Patel, Tiangui Huang, and Elizabeth Guevara. "An Extremely Rare Case of Advanced Metastatic Small Cell Neuroendocrine Carcinoma of Sinonasal Tract." Case Reports in Oncological Medicine 2016 (2016): 1–5. http://dx.doi.org/10.1155/2016/1496916.

Full text

Abstract:

Small cell neuroendocrine carcinoma (SNEC) is a rare form of malignancy. It mainly presents as bronchogenic neoplasm, and the extrapulmonary form accounts for only 0.1% to 0.4% of all cancers. These extrapulmonary tumors have been described most frequently in the urinary bladder, prostate, esophagus, stomach, colon and rectum, gall bladder, head and neck, cervix, and skin. Primary SNEC of the sinonasal tract is extremely rare with only less than 100 cases reported in the literature. Because of extreme rarity and aggressiveness of the tumor, the management for this entity varies considerably mandating multimodality approach. In this paper, we report a patient presented with left-sided facial swelling, and the histopathologic examination confirmed primary SNEC of left sinonasal tract. The tumor involved multiple paranasal sinuses with invasion into the left orbit and left infratemporal fossa and metastasized to cervical lymph nodes and bone. The patient encountered devastating outcome in spite of optimal medical management and treatment with palliative chemotherapy highlighting the necessity for further research of primary SNEC of head and neck.

APA, Harvard, Vancouver, ISO, and other styles

Sengoz, Meric, Ufuk Abacioglu, Taflan Salepci, Funda Eren, Fulden Yumuk, and Serdar Turhal. "Extrapulmonary Small Cell Carcinoma: Multimodality Treatment Results." Tumori Journal 89, no. 3 (2003): 274–77. http://dx.doi.org/10.1177/030089160308900308.

Full text

Abstract:

Aims and Background Extrapulmonary small cell carcinoma is a distinct entity that can occur in many sites, and it is pathologically similar to small-cell lung cancer. We report the results of a retrospective study of a multimodality treatment of 16 consecutive patients with a diagnosis of extrapulmonary small-cell carcinoma. Methods Primary tumor site was prostate in 2, gallbladder in 2, uterine cervix in 2, liver in 2, endometrium in 1, epididymis in 1, colon in 1, larynx in 1, breast in 1, and unknown primary tumor in 3 patients. Patients’ ages ranged from 19 to 79 years (median, 62). Nine patients had limited and 7 had extensive disease. Histologically, 14 were pure extrapulmonary small-cell carcinoma and 2 were mixed with squamous-cell carcinoma. Results Curative surgery was attempted in 8 patients. Seven patients received local-regional adjuvant radiotherapy. All patients, except the one with a breast primary, were treated with chemotherapy (mostly platinum-based regimens). Overall survival for all patients was 41% and 11% at 2 and 5 years, respectively (median survival, 14 months). Median survival for patients with limited disease was 25 months compared to 12 months for patients with extensive disease (P = 0.05). Conclusions Treatment results for extrapulmonary small-cell carcinoma are comparable to those of small-cell carcinomas of the lung. Extent of disease is a significant prognostic factor for survival.

APA, Harvard, Vancouver, ISO, and other styles

Ramdial, P. K., and A. Madaree. "Aggressive CD34-positive Fibrous Scalp Lesion of Childhood: Extrapulmonary Solitary Fibrous Tumor." Pediatric and Developmental Pathology 4, no. 3 (2001): 267–75. http://dx.doi.org/10.1007/s100240010140.

Full text

Abstract:

Although solitary fibrous tumor (SFT) was originally described as a pleural tumor, an increasing number of extrapleural sites of SFTs have been documented. This has been attributed not only to the heightened awareness of the spectrum of histopathological features that characterizes SFTs but also to the recognition of the role of CD34 immunostaining in soft tissue tumors in general, and in SFTs in particular. Despite the large number of documented extrapleural SFTs in adults, cranial SFTs are rare, having been documented in the meninges, scalp, and infratemporal fossa. Extrapleural SFTs are, to date, an unrecognized entity in children. We document an aggressive fibrous scalp lesion in a 30-month-old female child that demonstrated features common to benign cranial fasciitis and SFT. However, based on bright, diffuse CD34 antigen immunopositivity, a diagnosis of SFT was made. The need to include the CD34 antigen stain in a panel of immunohistochemical markers used to assess spindle cell lesions of childhood is emphasized.

APA, Harvard, Vancouver, ISO, and other styles

Osama, Md Ali, Smita Singh, Sahaj Prajapati, Subhasis Roy Choudhury, and Nishat Amina. "Mesenteric Tumor of an Infant: A Clinical and Pathological Surprise." Annals of Pathology and Laboratory Medicine 9, no. 1 (2022): C4–7. http://dx.doi.org/10.21276/apalm.3143.

Full text

Abstract:

Inflammatory myofibroblastic tumor (IMT) is a tumefactive proliferation of spindled myofibroblastic cells admixed with inflammatory infiltrate. This tumor has a predilection for pulmonary location and also involves visceral soft tissues in children and adults. Tumors in extrapulmonary locations like abdomen, mesentery, bowel, head & neck, genitourinary and musculoskeletal are more aggressive locally and mimic malignancy. IMTs from colon are very rare and are treated by surgical excision. We report a case of a 9-month old female with IMT of sigmoid colon with no bowel complaints, treated by complete surgical excision with no further treatment needed.

APA, Harvard, Vancouver, ISO, and other styles

Lesmana, Andy, Hapsari Retno Dewanti, Lenty BR Perangin Angin, et al. "Tuberculosis Mimicking-Musculoskeletal Tumor of The Hand: An Uncommon Case of Extrapulmonary Tuberculosis." (JOINTS) Journal Orthopaedi and Traumatology Surabaya 12, no. 2 (2023): 77–82. http://dx.doi.org/10.20473/joints.v12i2.2023.77-82.

Full text

Abstract:

Background: Musculoskeletal extrapulmonary tuberculosis is accounting for only 10-15% of all cases. Current attention has been focused on hand tuberculosis due to its increasing prevalence. This study describes an unusual case of extrapulmonary tuberculosis that manifested as a soft tissue tumor of the hand.Case Report: A 17-year-old male presented with a painful swollen part of the 3rd finger of the left hand. The mass was irregular and suppurative, with discoloration and foul smell. Laboratory results showed anemia and increased erythrocyte sedimentation rate. The computed tomography scan showed an isodense soft tissue (size 2.19 cm x 1.59 cm x 4.21cm) across the distal to the proximal part of 3rd phalanx bone to the metacarpal region with a decrease of phalanx bone density with no sign of bone destruction or any periosteal reaction. The histopathology study revealed a chronic granulomatous structure surrounded by epitheloid cells, datia Langhans cells, and caseating necrosis. The acid-fast staining confirmed the presence of bacilliform bacteria.Discussion: Extrapulmonary tuberculosis typically results from secondary hematogenous dissemination and reactivation of the main foci. There are no specific tests to diagnose musculoskeletal tuberculosis preoperatively, leading to delayed diagnosis. Histopathological examination and culture are needed to confirm the diagnosis.Conclusions: Slow progression and multiple differential diagnoses frequently result in a delayed diagnosis, which leads to complications. Initial radical excision and anti-tuberculosis multidrug therapy provide excellent functional outcomes and recurrence prevention.

APA, Harvard, Vancouver, ISO, and other styles

Tazelaar, Henry D., Kenneth P. Batts, and John R. Srigley. "Primary Extrapulmonary Sugar Tumor (PEST): A Report of Four Cases." Modern Pathology 14, no. 6 (2001): 615–22. http://dx.doi.org/10.1038/modpathol.3880360.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Lardinois, Didier, Walter Weder, Marina Roudas, et al. "Etiology of Solitary Extrapulmonary Positron Emission Tomography and Computed Tomography Findings in Patients With Lung Cancer." Journal of Clinical Oncology 23, no. 28 (2005): 6846–53. http://dx.doi.org/10.1200/jco.2005.10.116.

Full text

Abstract:

Purpose The aim of this prospective study was to assess the incidence and the nature of solitary extrapulmonary [18F] fluorodeoxyglucose (FDG) accumulations in patients with non–small-cell lung cancer (NSCLC) staged with integrated positron emission tomography and computed tomography (PET/CT) and to evaluate the impact on management. Patients and Methods A total of 350 patients with NSCLC underwent whole-body PET/CT imaging. All solitary extrapulmonary FDG accumulations were evaluated by histopathology, further imaging, or clinical follow-up. Results PET/CT imaging revealed extrapulmonary lesions in 110 patients. In 72 patients (21%), solitary lesions were present. A diagnosis was obtained in 69 of these patients, including 37 (54%) with solitary metastases and 32 (46%) with lesions unrelated to the lung primary. Histopathologic examinations of these 32 lesions revealed a second clinically unsuspected malignancy or a recurrence of a previous diagnosed carcinoma in six patients (19%) and a benign tumor or inflammatory lesion in 26 patients (81%). The six malignancies consisted of carcinoma of the breast in two patients, and carcinoma of the orbit, esophagus, prostate, and non-Hodgkin's lymphoma in one patient each. Benign tumors and inflammatory lesions included eight colon adenomas, four Warthin's tumors, one granuloma of the lower jaw, one adenoma of the thyroid gland, one compensatory muscle activity due to vocal chord palsy, two occurrences of arthritis, three occurrences of reflux esophagitis, two occurrences of pancreatitis, two occurrences of diverticulitis, one hemorrhoidal inflammation, and one rib fracture. Conclusion Solitary extrapulmonary FDG accumulations in patients with newly diagnosed lung cancer should be analyzed critically for correct staging and optimal therapy, given that up to half of the lesions may represent unrelated malignancies or benign disease.

APA, Harvard, Vancouver, ISO, and other styles

Manouchehr, Aghajanzadeh, Alavi Foumani Ali, Tangestaninejad Azita, et al. "Evaluation of demographic and rare clinical characteristics of patients with thoracic carcinoid tumor in Razi and Aria Hospitals of Rasht during 2006-2019." GSC Advanced Research and Reviews 11, no. 2 (2022): 050–56. https://doi.org/10.5281/zenodo.6770322.

Full text

Abstract:

Introduction: Carcinoid tumors are malignant neoplasms of low-malignant neuroendocrine cells. This study tended to evaluate the demographic and rare clinical characteristics of patients with thoracic carcinoid tumor during 2006-2016 at Razi and Aria Hospitals in Rasht. Materials and Methods: The present study was performed on records of 43 patients with lung carcinoid tumors referred to Razi and Aria Hospitals of Rasht during 2006-2019. Information on age, gender, rare clinical symptoms, smoking history, diagnosis tools, treatment and outcome were analyzed. Results: Of the 43 patients treated with definitive diagnosis of carcinoid tumor pathology, 31 patients had typic carcinoid tumor and 12 patients had atypic carcinoma (mean age 43.14±15.16 years). The most common clinical symptom was cough and hemoptysis. Two cases presented with Cushing’s syndrome. The most common diagnostic method in this study was simultaneous use of both CT scan and bronchoscopy. In 95.3% of cases, the tumor manifested as pulmonary and in 4.7% of cases it was extrapulmonary. Right lower lobe was the most common site of tumor involvement and lobectomy was the most frequent surgical procedure performed. Conclusion: based upon our study the most common clinical sign of thoracic carcinoid was cough and the tumor was pulmonary in 95.3% of cases. Right lower lobe was the most common site of involvement and the most frequent surgical procedure performed was lobectomy. The outcome was good.

APA, Harvard, Vancouver, ISO, and other styles

Kumar, Rajeev, Kapil Sikka, C. Preetam, Rakesh Kumar, and Prashant Durgapal. "A Rare Association of Inflammatory Myofibroblastic Tumor of Maxilla and Idiopathic Orbital Inflammatory Disease." An International Journal Clinical Rhinology 6, no. 1 (2013): 41–43. http://dx.doi.org/10.5005/jp-journals-10013-1146.

Full text

Abstract:

ABSTRACT Inflammatory myofibroblastic tumor (pseudotumor) is a rare tumor belonging to the family of fibrous mesenchymal tumors. Though it usually involves lungs, but extrapulmonary site involvement, especially head and neck region is rare. In this paper, we are presenting a 26-year-old male patient, with inflammatory myofibroblastic tumor of maxilla, with a rare association with a prior history of idiopathic orbital inflammatory disease, treated medically. The patient was treated surgically with complete excision of the pathology from maxilla. This case report intents to review the controversies in management of this tumor and also to enlighten the possible association between the orbital and maxillary pseudotumor. How to cite this article Preetam C, Kumar R, Sikka K, Kumar R, Durgapal P. A Rare Association of Inflammatory Myofibroblastic Tumor of Maxilla and Idiopathic Orbital Inflammatory Disease. Clin Rhinol An Int J 2013;6(1):41-43.

APA, Harvard, Vancouver, ISO, and other styles

Heymann, Jonas J., Rana S. Hoda, and Theresa Scognamiglio. "Polyclonal Napsin A Expression: A Potential Diagnostic Pitfall in Distinguishing Primary From Metastatic Mucinous Tumors in the Lung." Archives of Pathology & Laboratory Medicine 138, no. 8 (2014): 1067–71. http://dx.doi.org/10.5858/arpa.2013-0403-oa.

Full text

Abstract:

Context.—Napsin A is a useful marker for distinguishing primary from metastatic lung tumors. Mucinous lung tumors may be difficult to distinguish from metastatic mucinous tumors. Objectives.—To evaluate napsin A expression in lung and extrapulmonary mucinous tumors on both histology and cytology specimens and to determine napsin A's utility in differentiating primary from metastatic mucinous tumors. Design.—Napsin A immunohistochemistry was performed using a rabbit polyclonal antibody on formalin-fixed, paraffin-embedded surgical and fine-needle aspiration biopsy–derived, paraffin-embedded cell block specimens. Positive expression was defined as coarse, granular, cytoplasmic staining in 10% or more of tumor cells. Results.—Sixteen of 32 mucinous lung tumors (50%) and 16 of 33 extrapulmonary mucinous tumors (48%), including 15 of 18 of gastrointestinal origin (83%), expressed napsin A. Positivity was concordant between surgical and cell block specimens in 5 of 9 cases (56%). In 3 of 4 discordant cases, napsin A expression was detected on the surgical specimen but not the cell block. The cell block material in these cases was paucicellular. Conclusions.—Napsin A shows decreased sensitivity and specificity for mucinous lung tumors and is unlikely to be reliable as a sole immunohistochemical marker of lung origin for such tumors (52% specificity in this study). The high frequency of napsin A expression in gastrointestinal mucinous tumors makes it particularly unreliable in distinguishing metastatic gastrointestinal from primary lung mucinous tumors. However, napsin A expression analysis may facilitate distinguishing mucinous tumors of pulmonary from those of nongastrointestinal origin. Interpretation of napsin A staining may be problematic in mucinous tumor specimens of low cellularity such as cell blocks.

APA, Harvard, Vancouver, ISO, and other styles

Kurniawan, Joshua, Annisa Ananda, and Kasum Supriadi. "Tumor-Like Mass in Patient with Tuberculosis : Is It Really a Malignancy? a Case Report." Malahayati Nursing Journal 5, no. 8 (2023): 2796–803. http://dx.doi.org/10.33024/mnj.v5i8.10964.

Full text

Abstract:

ABSTRACT Tuberculosis (TB) is not all about chronic cough or hemoptysis. The clinical manifestation of TB could be pulmonary and extrapulmonary, with the later defined as any site other than the lung, affected by the TB. The global burden for tuberculosis is still heavy, standing as the second leading infectious killer after COVID-19 (above HIV/AIDS), TB holds the 13th place of the leading cause of death. The World Health Organization (WHO) predicted around 1.6 million people died from TB, and 10.6 million people fell ill with TB worldwide in 2021. Due to the various manifestations and limitations of the diagnostic tools, determining the diagnosis and treatment of TB has always been a challenge since a long time ago. To give appropriate therapy, making an accurate diagnosis is crucial. It is known that extrapulmonary tuberculosis manifestation often mimics malignancy, both clinically and radiologically. The treatment for these cases should include treatment for the infection and the affected organ or site, following the recommended therapy dose and duration. Neurological examination should be evaluated, especially for tuberculosis of the spine. Surgical approach should be considered for cases with neurological deficits, patient with spine-at-risk, progressive spinal deformity, severe pain, spinal instability, or uncertain diagnosis. Physical therapy could be considered to improve respiratory function, improving muscle strength, reducing the pain, repair/improve the range of motion, sensory function, improve quality of life, and prevent other complications. Keywords: Extrapulmonary Manifestation, Mimics Malignancy, Tuberculosis

APA, Harvard, Vancouver, ISO, and other styles

Fiske, Christina T., Alexandre S. de Almeida, Ayumi K. Shintani, Spyros A. Kalams, and Timothy R. Sterling. "Abnormal Immune Responses in Persons with Previous Extrapulmonary Tuberculosis in anIn VitroModel That SimulatesIn VivoInfection with Mycobacterium tuberculosis." Clinical and Vaccine Immunology 19, no. 8 (2012): 1142–49. http://dx.doi.org/10.1128/cvi.00221-12.

Full text

Abstract:

ABSTRACTPersons with previous extrapulmonary tuberculosis have reduced peripheral blood mononuclear cell cytokine production and CD4+lymphocytes compared to persons with previous pulmonary tuberculosis or latent tuberculosis infection, but specific defects related toMycobacterium tuberculosisinfection of macrophages have not been characterized. The objective of this study was to further characterize thein vitroimmune responses toM. tuberculosisinfection in HIV-seronegative persons with previous extrapulmonary tuberculosis. Peripheral blood mononuclear cells were isolated from HIV-seronegative persons with previous extrapulmonary tuberculosis (n= 11), previous pulmonary tuberculosis (n= 21), latentM. tuberculosisinfection (n= 19), and uninfected tuberculosis contacts (n= 20). Experimental conditions includedM. tuberculosis-infected macrophages cultured with and without monocyte-depleted peripheral blood mononuclear cells. Concentrations of interleukin 1β (IL-1β), IL-4, IL-6, CXCL8 (IL-8), IL-10, IL-12p70, IL-17, CCL2 (monocyte chemoattractant protein 1), tumor necrosis factor alpha (TNF-α), and gamma interferon (IFN-γ) were measured by multiplex cytokine array. WhenM. tuberculosis-infected macrophages were cocultured with monocyte-depleted peripheral blood mononuclear cells, IFN-γ (P= 0.01), TNF-α (P= 0.04), IL-10 (P< 0.001), and IL-6 (P= 0.03) exhibited similar continua of responses, with uninfected persons producing the lowest levels, followed by extrapulmonary tuberculosis cases, pulmonary tuberculosis controls, and persons with latentM. tuberculosisinfection. A similar pattern was observed with CXCL8 (P= 0.04), IL-10 (P= 0.02), and CCL2 (P= 0.03) when monocyte-depleted peripheral blood mononuclear cells from the four groups were cultured alone. Persons with previous extrapulmonary tuberculosis had decreased production of several cytokines, both at rest and after stimulation withM. tuberculosis. Our results suggest that persons who develop extrapulmonary tuberculosis have a subtle global immune defect that affects their response toM. tuberculosisinfection.

APA, Harvard, Vancouver, ISO, and other styles

Kriki, P., E. Thodis, S. Deftereos, et al. "A tumor-like manifestation of extrapulmonary tuberculosis in a hemodialysis patient." Clinical Nephrology 71, no. 06 (2009): 714–18. http://dx.doi.org/10.5414/cnp71714.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Remick, Scot C., and John C. Ruckdeschel. "Extrapulmonary and pulmonary small-cell carcinoma: Tumor biology, therapy, and outcome." Medical and Pediatric Oncology 20, no. 2 (1992): 89–99. http://dx.doi.org/10.1002/mpo.2950200202.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Belhamidi, M. S., B. Slioui, and A. Bensal. "PERITONEAL TUBERCULOSIS MIMIKING GASTROINTESTINAL STROMAL TUMOR." International Journal of Advanced Research 12, no. 01 (2024): 710–12. http://dx.doi.org/10.21474/ijar01/18175.

Full text

Abstract:

Abdominal TB is a common site of extrapulmonary tubercilosis, and peritoneal tuberculosis (PTB) is one of the most common manifestations of abdominal tuberculosis. The diagnosis of PTB can be made based on a combination of clinical, radiological, histological, and laboratory tests. The diagnosis can be easy in the presence of ascites with peritoneal granulations. some forms of PTB can make a differential diagnosis with peritoneal or digestive tract pathologies. some forms of PTB can make a differential diagnosis with peritoneal or digestive tract pathologies. We report a case of primary mesenteric tuberculosis mimicking gastrointestinal stromal tumor. The final diagnostic was performed using a combination of invasive and imaging techniques.

APA, Harvard, Vancouver, ISO, and other styles

Çamtosun, Ahmet, Huseyin Çelik, Ramazan Altıntaş, and Nusret Akpolat. "Primary Small Cell Carcinoma in Urinary Bladder: A Rare Case." Case Reports in Urology 2015 (2015): 1–3. http://dx.doi.org/10.1155/2015/789806.

Full text

Abstract:

Small cell carcinoma of bladder, which does not have a common and accepted treatment protocol, is a rare and highly aggressive tumor. It is mostly pulmonary originated; however, it can rarely be seen in extrapulmonary sites. We presented an interesting and uncommon case, in which the transitional cell tumor was found in the transurethral resection specimen, but the small cell carcinoma was detected in the final radical cystectomy material.

APA, Harvard, Vancouver, ISO, and other styles

Abdulhaleem, Khadijah, Mohammad Anas Dababo, and Eyas Othman. "Parotid Gland Solitary Fibrous Tumor Presenting as a Long Duration Mass: A Case Report." Case Reports in Pathology 2022 (February 24, 2022): 1–5. http://dx.doi.org/10.1155/2022/2097634.

Full text

Abstract:

The solitary fibrous tumor (SFT) is a tumor of uncertain histogenesis, affecting deep soft tissues, particularly the pleura (pulmonary) and extrapulmonary sites including thighs, retroperitoneum, other serosal surfaces, and cranial and spinal meninges. SFT and hemangiopericytoma are now considered the same entity, with general agreement on referring to this group of tumors as “SFT.” SFTs are generally benign tumors with small subsets of malignant ones. Moreover, they are well-circumscribed with a good prognosis after surgical resection. SFTs are uncommon in the head and neck and are quite rare in the parotid gland region. Here, we present a case of a 48-year-old female with SFT of the parotid gland region; the diagnosis was confirmed by positive immunohistochemical staining for Bcl-2, CD34, and STAT6. STAT6 immunohistochemistry is sensitive and specific for SFTs.

APA, Harvard, Vancouver, ISO, and other styles

Amante, Marcelo Fabián. "Hepatic perivascular epithelioid cell tumors: Benign, malignant, and uncertain malignant potential." World Journal of Gastroenterology 30, no. 18 (2024): 2374–78. http://dx.doi.org/10.3748/wjg.v30.i18.2374.

Full text

Abstract:

In 2013, the World Health Organization defined perivascular epithelioid cell tumor (PEComa) as “a mesenchymal tumor which shows a local association with vessel walls and usually expresses melanocyte and smooth muscle markers.” This generic definition seems to better fit the PEComa family, which includes angiomyolipoma, clear cell sugar tumor of the lung, lymphangioleiomyomatosis, and a group of histologically and immunophenotypically similar tumors that include primary extrapulmonary sugar tumor and clear cell myomelanocytic tumor. Clear cell tumors with this immunophenotypic pattern have also had their malignant variants described. When localizing to the liver, preoperative radiological diagnosis has proven to be very difficult, and most patients have been diagnosed with hepatocellular carcinoma, focal nodular hyperplasia, hemangioma, or hepatic adenoma based on imaging findings. Examples of a malignant variant of the liver have been described. Finally, reports of malignant variants of these lesions have increased in recent years. Therefore, we support the use of the Folpe criteria, which in 2005 established the criteria for categorizing a PEComa as benign, malignant, or of uncertain malignant potential. Although they are not considered ideal, they currently seem to be the best approach and could be used for the categorization of liver tumors.

APA, Harvard, Vancouver, ISO, and other styles

Prokešová, Nikola, Petr Valha, Miloš Velemínský, Pavla Vítková, and Adéla Stehlíková. "Cervical tuberculosis in a postmenopausal patient." Česká gynekologie 86, no. 6 (2021): 392–96. http://dx.doi.org/10.48095/cccg2021392.

Full text

Abstract:

Objective: Description of a case of extrapulmonary genital tuberculosis of the uterine cervix in a postmenopausal patient. Case report: A 66-year-old patient with a history of metrorrhagia, an ulcerated process in the area of the uterine cervix and vagina, with infiltration of parametria, serosanguinolent discharge and progressive cachectization was admitted to the oncogynecological center of the Hospital of České Budějovice, a. s. As part of the diagnostics, physical examination, colposcopy, targeted biopsy, polymerase chain reaction (PCR) and microbiological examination, oncogynecological ultrasound and CT examination were performed. Clinically, the lesion acted as an advanced tumor. However, no malignant cells were detected in the biopsy and the histopathological finding corresponded to a granulomatous inflammatory condition with giant cell histiocytic elements. Bacterial DNA of Mycobacterium tuberculosis complex was detected by PCR testing. The patient underwent controlled antituberculosis treatment with regular gynecological examinations. Conclusion: Tuberculosis of the uterine cervix occurs rarely. Its clinical manifestation may mimic the tumor process. Diagnosis is based on the identification of the causative agent and treatment consists of long-term controlled administration of antituberculotics, and in rare cases, combination with surgical treatment. Key words: extrapulmonar tuberculosis – genital tuberculosis – uterine cervix – Mycobacterium tuberculosis complex

APA, Harvard, Vancouver, ISO, and other styles

Chang, Jinjia, Wenhua Li, Qijie Jian, et al. "Circulating tumor DNA guided therapeutic strategies for colorectal cancer patients with multiple small pulmonary-limited nodules: An open-label, prospective, phase II cohort study." Journal of Clinical Oncology 41, no. 16_suppl (2023): e15645-e15645. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e15645.

Full text

Abstract:

e15645 Background: The clinical diagnosis and treatment of small pulmonary nodules (suspected to be lung metastases) in advanced colorectal cancer (CRC) patients remain controversy. Previous studies have shown that tumor-informed circulating tumor DNA (ctDNA) testing with blood sample can sensitively detect recurrence or metastasis of CRC patients. This study was designed to explore the clinical value of tumor-informed ctDNA test in metastatic CRC patients with small pulmonary-limited nodules. We aimed to identify the low-risk patients for de-escalation therapy, as well as high-risk patients with no evidence of disease (NED) for escalation therapy. Methods: This is an ongoing, open-label, prospective and phase II cohort study (NCT 05495672). According to the longest diameter of the pulmonary nodule, patients were divided into two cohorts: Cohort 1(0-1cm) and Cohort 2 (1-2cm). Tumor-informed ctDNA test (OriMIRACLE S) would be performed every three months until progression or 2 years. The treatment strategy of each patient is decided by a multidisciplinary team depending on ctDNA and lung CT scan results. In general, negative minimal residual disease (MRD) patients will receive only regular follow-up. Patients with positive MRD will receive intensive examination and local treatments for pulmonary nodules such as surgery, radio frequency ablation or stereotactic body radiotherapy combined with or without systemic therapeutic treatment, aiming to achieve NED or cure. Results: From June 2022 to December 2022, a total of 26 patients were screened in the group, one patient was eliminated (with extrapulmonary metastasis), and a total of 25 patients were successfully enrolled. At present, 1 patient died (by acute intestinal perforation), 4 patients were excluded from the group (with the emergence of extrapulmonary metastasis), and a total of 20 patients were in the group. The positive rate of MRD in baseline were 4/11(36.4%) for Cohort 1 and 10/14 (71.4%) for Cohort 2, respectively. Notably, in Cohort 1, 3 of 4 patients with positive MRD at baseline were examined extrapulmonary metastasis during the follow-up examination. Conclusions: Our preliminary results suggested that the positive rate of MRD were higher in Cohort 2 than Cohort 1. Patients with pulmonary nodule less than 1 cm tended to develop extrapulmonary metastasis if baseline MRD was positive. In such circumstances, more intensive follow-up examination is suggested to prevent early disease progression. Clinical trial information: NCT05495672 .

APA, Harvard, Vancouver, ISO, and other styles

Patel, Devin P., Yogesh S. Gandhi, Keith E. Sommers, Devanand Mangar, and Enrico M. Camporesi. "Primary Pulmonary Malignant Fibrous Histiocytoma." Case Reports in Pulmonology 2015 (2015): 1–5. http://dx.doi.org/10.1155/2015/381276.

Full text

Abstract:

Malignant fibrous histiocytoma (MFH) is one of the most common adult soft tissue sarcomas. MFH is very aggressive and is most often found in the extremities and the retroperitoneum, but it can manifest at other sites. Though the lungs are the most common sites of metastasis, they rarely present there as a primary tumor. Our report describes a rare case of a primary MFH tumor in the lung. Careful diagnostic procedure should be followed to ensure the tumor does not have extrapulmonary origins. Though MFH is highly invasive and deadly, surgical excision of the tumor has been shown to be successful.

APA, Harvard, Vancouver, ISO, and other styles

Sarkar, Nirmal Kanti, and Md Mofizur Rahman Mia. "Tuberculous Abscess of the Chest Wall." Journal of Bangladesh College of Physicians and Surgeons 40, no. 2 (2022): 136–37. http://dx.doi.org/10.3329/jbcps.v40i2.58698.

Full text

Abstract:

Chest wall tuberculosis (TB) is a rare form of extrapulmonary TB, especially in an immunocompetent patient. The disease may resemble a pyogenic abscess or tumor. We present a young lady who developed a slowly growing chest wall swelling, proven as tuberculous etiology. J Bangladesh Coll Phys Surg 2022; 40: 136-137

APA, Harvard, Vancouver, ISO, and other styles

Sahin, Mehmet F., Muhammet A. Beyoglu, Merve M. Kıran, and Erdal Yekeler. "A rare lung tumor: Primary pulmonary synovial sarcoma." Journal of Cancer Research and Therapeutics 19, Suppl 2 (2023): S901—S903. http://dx.doi.org/10.4103/jcrt.jcrt_1810_21.

Full text

Abstract:

ABSTRACT Synovial sarcoma is one of the rare soft tissue sarcomas occurring in the periarticular region originating from synovia. Synovial sarcomas occur less frequently in the neck, tongue, larynx, mediastinum, heart, lung, abdominal wall, small intestine, mesentery, and retroperitoneum. Primary pulmonary synovial sarcoma is a poor pathological condition without extrapulmonary involvement. In these rapidly progressing tumors, making quick decisions is important and performing complete resection is the best treatment that contributes to survival. Herein, we present a case of primary pulmonary synovial sarcoma in which we were able to achieve long-term survival with the multimodal approach after complete resection.

APA, Harvard, Vancouver, ISO, and other styles

Koerniawan, Heru Sutanto, Wayan Yudiana, I. Made Bayu Indratama, Novitasari Novitasari, and Yofatifa Ramandey. "Orchioepididymitis Tuberculosis in Limited Setting: A Case Report and Brief Literature Review." Open Access Macedonian Journal of Medical Sciences 8, no. C (2020): 209–12. http://dx.doi.org/10.3889/oamjms.2020.5460.

Full text

Abstract:

BACKGROUND: Tuberculosis (TB) remains a major global health concern and highly prevalent in Indonesia. Extrapulmonary TB presents a diagnostic and therapeutic challenge. Clinically, orchioepididymitis TB of the scrotum often cannot be distinguished from lesions such as tumor and infarction, especially in apparently healthy patients.  CASE REPORT: We present a rare case of unilateral orchioepididymitis TB which present as a testicular tumor resulted in the removal of the testis.  CONCLUSION: The pathological finding revealed orchioepididymitis TB.

APA, Harvard, Vancouver, ISO, and other styles

Dixit, Sapna, Nagendra Kumar, Anand Srivastava, Rajiv Garg Garg, and Sumaira Qayoom. "An Interesting Case of Extrapulmonary Manifestation of a Rare Mediastinal Tumor-Schwannoma." Clinical and Research Journal in Internal Medicine 5, no. 2 (2024): 184–87. https://doi.org/10.21776/ub.crjim.2024.005.02.13.

Full text

Abstract:

A 23-year-old nonsmoking, female was sent to respiratory medicine department with suspicion of malignant intrathoracic lesion. The diagnosis was confirmed by performing Computed tomography of thorax. Suspicion for Benign posterior mediastinal schwannoma was raised as it is one of the most common posterior mediastinal mass. Complete resection of the mass was done & findings were confirmed by histopathological examination. We present here a case of posterior mediastinal schwannoma who presented with complaints of left-sided anhidrosis, headache, frequent tingling sensation & weakened hand grip for 4 years. To study the clinical presentation, course of progression, diagnosis & management of posterior mediastinal schwannoma. A case of posterior mediastinal schwannoma was studied with regular investigations, surgical management & follow-up. The patient recovered with complete resolution & uneventful postoperative period. In the list of common differential diagnoses for posterior mediastinal masses neurogenic tumors acquire the top position. Currently, video-assisted thoracoscopic surgery is the technique of choice for the diagnosis and treatment of benign posterior mediastinal masses as it is less invasive& has fewer complications. Survival rates for patients with benign neurogenic tumors are excellent. The benign posterior mediastinal schwannoma is completely resectable with less recurrence.

APA, Harvard, Vancouver, ISO, and other styles

GATZINSKY, P., P. MYKEN, and V. MANTOVANI. "Intrathoracic extrapulmonary hemangiopericytomaLate local recurrence after radical extirpation of a large tumor." European Journal of Cardio-Thoracic Surgery 8, no. 6 (1994): 331–32. http://dx.doi.org/10.1016/s1010-7940(05)80094-6.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Saravanan, ManickamNeethirajan, Kota Venugopal, and Balbir Singh. "Extrapulmonary inflammatory myofibroblastic tumor with synchronous involvement of the liver and appendix." Clinical Cancer Investigation Journal 5, no. 2 (2016): 175. http://dx.doi.org/10.4103/2278-0513.176250.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Tipirneni, Niharika, and Marc O. Siegel. "Pulmonary and Peritoneal Tuberculosis Associated with Tumor Necrosis Factor-Alpha Inhibitor Use: A Case Report and Review of the Literature." Case Reports in Pulmonology 2012 (2012): 1–4. http://dx.doi.org/10.1155/2012/598634.

Full text

Abstract:

The association between the use of tumor necrosis factor-αinhibitors and the increased risk of granulomatous infections, especially tuberculosis, has been well documented. Given the rapidly expanding list of inflammatory conditions for which tumor necrosis factor-αinhibitors are receiving FDA approval, the incidence of tuberculosis in this patient population has increased. Despite heightened awareness by physicians, the diagnosis of tuberculosis can remain challenging, given that extrapulmonary sites of infection are more frequently involved. We present a case of pulmonary and peritoneal tuberculosis in a gentleman being treated with a tumor necrosis factor-αinhibitor and discuss the diagnostic challenges of establishing the diagnosis.

APA, Harvard, Vancouver, ISO, and other styles

Gallego, Lorena, Tania R. Santamarta, Verónica Blanco, Luis García-Consuegra, Tommaso Cutilli, and Luis Junquera. "Inflammatory Myofibroblastic Tumor of the Lung and the Maxillary Region: A Benign Lesion with Aggressive Behavior." Case Reports in Dentistry 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/879792.

Full text

Abstract:

Inflammatory myofibroblastic tumor (IMT) is a rare mass-forming lesion characterized by fibroblastic or myofibroblastic spindle cell proliferation with varying degrees of inflammatory cell infiltration. Although it has been reported in virtually every organ in the body, the lung is the most common site of involvement. Extrapulmonary IMTs, although rare, have been reported and are characterized by different, more aggressive behavior. We report an extremely rare case of maxillary metastases of pulmonary IMT. Lung IMT was initially misdiagnosed, and oral lesion mimicked clinically and radiologically a radicular cyst. On histologic examination, cells exhibited diffuse and intense immunoreactivity forα-smooth muscle actin and vimentin whereas both pulmonary and oral IMTs presented absence of cellular atypia and lack of expressivity of oncogenic determinants. Distant metastases of lung IMT are extremely unusual, and this is the first report to our knowledge with this particular clinical course. Despite the possibility that the present case could also represent a metachronous multifocal IMT, with pulmonary and extrapulmonary lesions, similar histopathological and immunohistochemical patterns in lung and maxillary region suggest a metastatic course.

APA, Harvard, Vancouver, ISO, and other styles

Kim, G. E., Y. P. Cho, D. H. Chung, T. W. Kwon, and O. J. Kim. "Inflammatory Pseudotumor of Carotid Artery: A Case Report." Cardiovascular Surgery 7, no. 3 (1999): 342–47. http://dx.doi.org/10.1177/096721099900700313.

Full text

Abstract:

Inflammatory pseudotumor is an uncommon round and spindle cell proliferative lesion of unknown etiology that occurs most commonly in the lung. But it also occurs in diverse extrapulmonary locations such as the abdomen, retroperitoneum, pelvis, heart, head and neck, upper respiratory tract, trunk, bladder and extremities. The extrapulmonary inflammatory pseudotumor is often larger, less well circumscribed and multinodular. Proximity of the tumor to vital structures or involvement of vital organs compromises the opportunity for complete resection, thus higher recurrence rates are often reported even after surgical treatment. The authors report a case of inflammatory pseudotumor originating from the common carotid artery in a 42-year-old female patient with a rapidly growing neck mass, treated by en-bloc resection of inflammatory pseudotumor and a long segment of common carotid artery followed by PTFE graft interposition.

APA, Harvard, Vancouver, ISO, and other styles

Eberhardt, Joshua M., Karen Brown, Shelly Lo, Suneel Nagda, and Sherri Yong. "Extrapulmonary Small Cell Carcinoma of the Anal Canal: A Case Report and Review of the Literature." Case Reports in Medicine 2012 (2012): 1–5. http://dx.doi.org/10.1155/2012/341432.

Full text

Abstract:

Purpose. Extrapulmonary small cell carcinoma affecting the anal canal is a rare and poorly understood entity which can, in its early stages, masquerade as benign anorectal disease such as hemorrhoids.Methods. We report a case of this rare malignancy which initially presented with hematochezia and anal pain. We also review the literature with regard to previously described cases and management strategies including the role of surgery.Results. Despite aggressive multidisciplinary treatment consisting of chemotherapy and radiation, the disease progressed rapidly with dissemination occurring only three months after completion of treatment. Because of the aggressive nature of this tumor, the treatment options for this almost universally fatal malignancy are often palliative in nature.Conclusion. Chemoradiotherapy is likely the most reasonable approach to extrapulmonary small cell carcinoma of the anal canal given its aggressiveness.

APA, Harvard, Vancouver, ISO, and other styles

Modh, Vidhi Dineshkumar, Preeti Jhaveri, and Hinal Gajjar. "Solitary fibrous tumor of nasal cavity: A case report." Indian Journal of Pathology and Oncology 11, no. 2 (2024): 206–9. http://dx.doi.org/10.18231/j.ijpo.2024.045.

Full text

Abstract:

Solitary fibrous tumor is fibroblastic tumor, located mostly in deep soft tissue as well as extrapulmonary sites. In the present case, a 27-year female presented with complain of bilateral nasal blockage (right &#62;left) with history of nasal bleed. The CT scan report revealed p/o hypervascular nasal polyp and sinusitis. Patient underwent excision of granulomatous mass arising from lateral nasal wall in right nasal cavity. The pathological report stated nasal tumor with hemangiopericytoma like pattern with differential diagnosis of 1) Solitary fibrous tumor – right nasal cavity 2) Glomangiopericytoma; further Immunohistochemistry was positive for CD34 (membranous) and STAT6 (nuclear) which leads to final diagnosis of Solitary fibrous tumor – right nasal cavity. Histopathological characteristics serve as the primary criteria for differentiating this condition from other entities.

APA, Harvard, Vancouver, ISO, and other styles

Ladenstein, R., U. Pötschger, M. Le Deley, et al. "A prognostic score at diagnosis for Ewing tumor patients with metastatic disease at extrapulmonary sites." Journal of Clinical Oncology 27, no. 15_suppl (2009): 10544. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.10544.

Full text

Abstract:

10544 Background: To assess prognostic factors at diagnosis in prospectively treated patients with primary extra-pulmonary metastatic Ewing tumors (EPM-ET) of the EURO-E.W.I.N.G. 99 Study. Methods: From 1999 to 2005, 281 patients were enrolled. Median age was 16.2 years (0.4–49). Primary site was extremity in 84 patients and axial in 197 (115 pelvic sites), with a tumor volume >200ml in 171 patients. Treatment consisted of 6 VIDE cycles, one VAI/VAC cycle, local treatment (surgery and/or radiotherapy), and high-dose busulfan-melphalan followed by peripheral stem cell transplantation (HDT/SCT). Results: After a median follow up of 3.8 years, event-free survival (EFS) and overall survival (OS) at 3 years for all 281 patients were 27%±3% and 34%±4%. Six VIDE cycles were completed by 250 patients (89%); 169 (60%) received HDT/SCT. Cox regression analyses demonstrated increased risk for patients with more than two bone metastatic sites (hazard ratio: HR 2.0), a primary tumor volume >200ml (HR 1.8), bone marrow metastases (HR 1.6), age >14 years (HR 1.6), and additional lung metastases (HR 1.5). A risk score based on these HR identified three risk groups with EFS rates of 50% for scores <_3 (82 patients), 25% for scores >3 to <5 (102 patients), and 10% for scores >_5 (70 patients), p< 0.0001. Conclusions: A proportion of EPM-ET patients may survive with intensive multimodal therapy. Age, tumor volume, and extent of metastatic spread are relevant risk factors. A score based on these factors identifies EPMD-ET patients with a more favorable outlook at diagnosis and may facilitate risk adapted treatment approaches. No significant financial relationships to disclose.

APA, Harvard, Vancouver, ISO, and other styles

Kontsevaya, Anna Y., Mariia A. Krylovetskaia, Olga A. Malikhova, and Igor G. Komarov. "Endoscopic semiotics of metastatic bronchial tumors." Journal of Modern Oncology 23, no. 1 (2021): 100–104. http://dx.doi.org/10.26442/18151434.2021.1.200714.

Full text

Abstract:

Aim. To study the possibilities of bronchoscopy in the detection and evaluation of metastatic lung tumors. Materials and methods. From 2017 to September 2020, 3719 bronchoscopies, including 1081 biopsies during bronchoscopy were performed at the Blokhin National Medical Research Center of Oncology. According to the results of the morphological verification, 40 patients had been diagnosed with lung metastasis. Results. Endobronchial metastatic tumors from extrapulmonary malignancies are quite rare. After had studying 40 cases of metastatic bronchial tumors, we found that the most commonly primary malignancies associated with endobronchial metastases were breast cancer (12 patients), colorectal cancer (6 patients) and thyroid cancer (4 patients). All patients who had been diagnosed with the pathology during the bronchoscopy had been required to make a biopsy for the purpose of morphological verification. Conclusion. The value of bronchoscopy lies in the possibility not only of the detailed visual studying and detecting the tumor pathology of the bronchial tree, but also of obtaining material for morphological analysis. In this regard, the role of biopsy during bronchoscopy is extremely important. In the visual signs of tumor lesion, it is necessary to take multiple biopsies from different parts of the tumor.

APA, Harvard, Vancouver, ISO, and other styles

Kakimoto, Tomoo, Mamoru Sasaki, Shojiroh Morinaga, Robert Nakayama, and Naoto Minematsu. "Asymptomatic Pulmonary Artery Intimal Sarcoma with Chest Wall Metastasis as an Initial Manifestation: An Autopsy Case." Case Reports in Medicine 2018 (May 27, 2018): 1–5. http://dx.doi.org/10.1155/2018/6153658.

Full text

Abstract:

Pulmonary artery intimal sarcoma (PAIS) is a rare mesenchymal malignancy arising in the pulmonary trunk or proximal pulmonary artery and shows intraluminal growth. Clinical manifestations in PAIS are predominantly related to the pulmonary artery embolism, so cases with initial symptoms related to an extrapulmonary metastasis are unusual. The present report describes an 82-year-old man without any cardiopulmonary symptoms who was detected with an abnormal shadow on chest radiography during a routine health checkup. Contrast medium-enhanced chest computed tomography revealed an enhancing mass in the right pulmonary artery, pulmonary nodules, and a chest wall tumor corresponding to the abnormal shadow observed using chest radiography. A core needle biopsy for the chest wall tumor determined a pathological diagnosis of unclassified sarcoma. The patient was diagnosed with PAIS on the basis of clinical, radiological, and pathological correlations. He was scheduled to receive supportive care, but died of respiratory failure 1 year from the first visit. An autopsy revealed the pleomorphic sarcoma occupying the entire lumen of the right pulmonary artery with the only site of extrapulmonary metastasis in the chest wall. We should be aware of rare cases of asymptomatic PAIS found through routine health checkups.

APA, Harvard, Vancouver, ISO, and other styles

Manouchehr Aghajanzadeh, Ali Alavi Foumani, Azita Tangestaninejad, et al. "Evaluation of demographic and rare clinical characteristics of patients with thoracic carcinoid tumor in Razi and Aria Hospitals of Rasht during 2006-2019." GSC Advanced Research and Reviews 11, no. 2 (2022): 050–56. http://dx.doi.org/10.30574/gscarr.2022.11.2.0090.

Full text

Abstract:

Introduction: Carcinoid tumors are malignant neoplasms of low-malignant neuroendocrine cells. This study tended to evaluate the demographic and rare clinical characteristics of patients with thoracic carcinoid tumor during 2006-2016 at Razi and Aria Hospitals in Rasht. Materials and Methods: The present study was performed on records of 43 patients with lung carcinoid tumors referred to Razi and Aria Hospitals of Rasht during 2006-2019. Information on age, gender, rare clinical symptoms, smoking history, diagnosis tools, treatment and outcome were analyzed. Results: Of the 43 patients treated with definitive diagnosis of carcinoid tumor pathology, 31 patients had typic carcinoid tumor and 12 patients had atypic carcinoma (mean age 43.14±15.16 years). The most common clinical symptom was cough and hemoptysis. Two cases presented with Cushing’s syndrome. The most common diagnostic method in this study was simultaneous use of both CT scan and bronchoscopy. In 95.3% of cases, the tumor manifested as pulmonary and in 4.7% of cases it was extrapulmonary. Right lower lobe was the most common site of tumor involvement and lobectomy was the most frequent surgical procedure performed. Conclusion: based upon our study the most common clinical sign of thoracic carcinoid was cough and the tumor was pulmonary in 95.3% of cases. Right lower lobe was the most common site of involvement and the most frequent surgical procedure performed was lobectomy. The outcome was good.

APA, Harvard, Vancouver, ISO, and other styles

Xiaoyan, Zhang1 5.-7* Lichao Sun2 5.-7. Bei Wang3 5.-7. Min Liu4-7. Qing Zhao1 5.-7. and Ye Wang. "A Large Volume of Unilateral Pleural Effusion Caused by Mediastinal Mass." Mega Journal of Case Reports 7, no. 3 (2024): 2001–9. https://doi.org/10.5281/zenodo.10894510.

Full text

Abstract:

IntroductionPleural effusion occurs due to an underlying medical condition that affects the balance in the fluiddistribution within the body (transudative effusion) or directly affects the pleura (exudative effusion),resulting in an accumulation of fluid in the pleural space [1]. The diagnosis of pleural effusion involvesa combination of patient history, physical examination, and diagnostic tests, including chest imaging,thoracentesis, and laboratory analysis of the pleural fluid. In general, the presence of a transudativepleural effusion suggests that extrapulmonary conditions like heart failure or cirrhosis and that it isexpected to occur on both sides of the chest. Conversely, exudative fluid accumulation indicates thatlocal pleural lesion like tumor growth or inflammation are the probable cause of the fluid buildup andmay often manifest on just one side of the chest. Here we would like to present a large volume ofunilaterally transudative pleural effusion case caused by extrapulmonary condition.

APA, Harvard, Vancouver, ISO, and other styles

Meteroglu, Fatih, Atalay Sahin, and Sevval Eren. "A Case of Hydatid Cyst Mimicking Superior Sulcus Tumor: Intrathoracic, Extrapulmonary, Intraosseous Location." Respiratory Case Reports 2, no. 1 (2013): 32–34. http://dx.doi.org/10.5505/respircase.2013.68077.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Ismail, Heba, Susan Murin, and Brian M. Morrissey. "Pulmonary and Extrapulmonary Noncaseating Granulomas Due to Tumor Necrosis Factor-Alpha Blocker Therapy." Chest 138, no. 4 (2010): 81A. http://dx.doi.org/10.1378/chest.10867.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Terashima, T., C. Morizane, H. Ueno, et al. "Extrapulmonary neuroendocrine tumors: An institutional experience of 337 patients at the National Cancer Center Hospital in Japan." Journal of Clinical Oncology 29, no. 4_suppl (2011): 293. http://dx.doi.org/10.1200/jco.2011.29.4_suppl.293.

Full text

Abstract:

293 Background: Extrapulmonary neuroendocrine tumors (EPNET) are a rare and heterogeneous disease entity, and little information regarding these tumors is available. The aim of the present study was to clarify the clinical behavior, treatment strategy, and outcome of EPNET arising from various primary sites. Methods: We retrospectively reviewed the medical records of 337 patients with pathologically confirmed NET arising from extrapulmonary site between January 2000 and December 2008 at the National Cancer Center Hospital of Japan. Results: The major primary tumor site was the rectum followed by the pancreas and stomach. Among the gastrointestinal tract tumors, 113 patients had NET from the foregut, 92 patients from the hindgut, and only 4 patients from the midgut. The median patient age was 60 years, and 57% of the patients were male. The histologic grade was as follows: 39% were well-differentiated neuroendocrine tumors (WDNET); 20% were well-differentiated neuroendcrine carcinomas (WDNEC); 33% were poorly differentiated neuroendocrine carcinomas (PDNEC); and 8% were mixed exocrine-endocrine tumors (Mixed). Most NETs from the rectum or duodenum are WDNET, whereas the ratio of PDNEC was high among NET from the genital organs or esophagus. The treatment strategy was associated with the clinical stage or the primary organ; in particular, 94% of the localized rectal NET were resected endoscopically. The 2-year survival rate for all the patients were 70%. A multivariate analysis demonstrated that distant disease of clinical stage and PDNEC of histological grade had a stronger impact on a poor outcome than the primary tumor site. The 2-year survival rate among the patients with WDNET, WDNEC and PDNEC were 97%, 80% and 36%, respectively, and 94%, 72%, and 32% of the patients had localized, regional, and distant disease, respectively. Conclusions: Japanese patients with EPNET have different clinicopathological features such as the primary organ or treatment procedure compared with previous reports in Western countries. Identifying the precise clinical stage and histological grade of patients with NET is essential because these factors influence the patient outcome. No significant financial relationships to disclose.

APA, Harvard, Vancouver, ISO, and other styles

Pennington, Kelly, Humberto C. Sasieta, Guiherme P. Ramos, et al. "Flow Cytometric Immune Profiling in Infliximab-Associated Tuberculosis." Clinical Medicine Insights: Case Reports 10 (January 1, 2017): 117954761772477. http://dx.doi.org/10.1177/1179547617724776.

Full text

Abstract:

Tumor necrosis factor α antagonists are increasingly used to treat inflammatory and autoimmune disorders and are associated with increased risk of active tuberculosis. Diagnosis of active tuberculosis in patients taking tumor necrosis factor α antagonists can be challenging owing to increased incidence of extrapulmonary manifestations and false-negative results on current available diagnostic tests. We present a case of a young woman on infliximab for ulcerative colitis who presented with disseminated tuberculosis. As part of a research study, we performed flow cytometric immune profiling, which has previously not been reported in patients with active tuberculosis taking tumor necrosis α antagonists. The flow cytometry results were within the positive thresholds for tuberculosis infection. Flow cytometric immune profiling may be a valid diagnostic tool for patients taking tumor necrosis factor α antagonists.

APA, Harvard, Vancouver, ISO, and other styles

Abbasova, Daria V., Svetlana B. Polikarpova, Nikolai A. Kozlov, Madina P. Baranova, Irina P. Kovalenko, and Elena I. Ignatova. "Neuroendocrine carcinoma of the prostate (review of the literature)." Journal of Modern Oncology 21, no. 3 (2019): 52–55. http://dx.doi.org/10.26442/18151434.2019.3.190673.

Full text

Abstract:

Neuroendocrine neoplasia (NEC) of the prostate gland is a rather rare extrapulmonary neuroendocrine carcinoma and makes up only 0.5 to 1% of all malignant neoplasms of this localization. NEC of the prostate gland is a tumor of epithelial origin, histologically and immunohistochemically identical to analogues in the lungs and digestive system. When stained with hemotoxylin-eosin, neuroendocrine cells cannot always be visualized; they are best recognized by the immunohistochemical method of investigation using specific markers. Currently, a number of neuroendocrine markers are used, the expression of which may indicate a neuroendocrine nature. Androgen neuroendocrine cells themselves are independent and do not cause an increase in the concentration of prostate-specific antigen. Prostate NECs are represented by some histological forms according to WHO classification (2015): 1. Adenocarcinoma with focal neuroendocrine differentiation. 2. Well-differentiated neuroendocrine tumor. 3. Small cell neuroendocrine cancer is a high - grade tumor with high malignant potential. 4. Large cell neuroendocrine cancer is a high - grade tumor. Due to the rarity of NEC of the prostate, a specific algorithm for diagnosis and treatment has not been developed, as a rule, they are similar to methods of other malignant forms of prostate cancer and neuroendocrine tumors.

APA, Harvard, Vancouver, ISO, and other styles

Roumpou, Afroditi, Argyro-Ioanna Ieronimaki, Aspasia Manta, et al. "A Novel Pathogenic Variant of DICER1 Gene in a Young Greek Patient with 2 Different Sex-Cord Ovarian Tumors and Multinodular Goiter." International Journal of Molecular Sciences 26, no. 5 (2025): 1990. https://doi.org/10.3390/ijms26051990.

Full text

Abstract:

DICER1 syndrome (DICERs) represents a tumor predisposition genetic syndrome, inherited in an autosomal dominant manner. Germline loss-of-function variants of the DICER1 gene lead to impaired processing of microRNA, gene expression, and increased risk of tumorigenesis. Although pleuropulmonary blastoma (PPB) is the hallmark of the syndrome, multiple extrapulmonary malignant and non-malignant conditions have also been described, including multinodular goiter (MNG) and sex-cord stromal tumors. MNG is one of the most common components and is associated with an increased risk of thyroid carcinoma. Sertoli–Leydig cell tumor (SLCT) represents the most prevalent type of sex-cord stromal tumor associated with the syndrome, whereas juvenile granulosa cell tumor (JGCT) is considered to be a very rare phenotype. They both may present with abdominal pain due to mass effect and menstrual irregularities in case of hormone production. Although they exhibit low rates of mortality, recurrence rates highly depend on the grade of malignancy. Herein, we report a novel pathogenic DICER1 variant associated with MNG, bilateral ovarian SLCT, and JGCT in a young Greek patient. Clinicians should be aware of a potential germline DICER1 variant when evaluating MNG in young patients, especially if it coexists with other neoplasms.

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!