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1

Downs, John B. "Extubation criteria." Critical Care Medicine 14, no. 2 (1986): 169. http://dx.doi.org/10.1097/00003246-198602000-00022.

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Templeton, T. Wesley, Eduardo J. Goenaga-Díaz, Martina G. Downard, et al. "Assessment of Common Criteria for Awake Extubation in Infants and Young Children." Anesthesiology 131, no. 4 (2019): 801–8. http://dx.doi.org/10.1097/aln.0000000000002870.

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Abstract Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New Background Practice patterns surrounding awake extubation of pediatric surgical patients remain largely undocumented. This study assessed the value of commonly used predictors of fitness for extubation to determine which were most salient in predicting successful extubation following emergence from general anesthesia with a volatile anesthetic in young children. Methods This prospective, observational study was performed in 600 children from 0 to 7 yr of age. The presence or absence of ni
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Bösel, Julian. "Who Is Safe to Extubate in the Neuroscience Intensive Care Unit?" Seminars in Respiratory and Critical Care Medicine 38, no. 06 (2017): 830–39. http://dx.doi.org/10.1055/s-0037-1608773.

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AbstractPatients admitted to the neuroscience intensive care unit (NICU) may have respiratory compromise from either central or peripheral neurological pathology, and may hence require intubation and mechanical ventilation for very diverse reasons. Liberation from invasive ventilation, that is, extubation, at the earliest possible time is a widely accepted principle in intensive care. For this, classic extubation criteria have been established in the general critical care setting, mainly targeting pulmonary function and cooperativeness of the patient. However, classic extubation criteria have
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DEHAVEN, C. BRYAN, JAMES M. HURST, and RICHARD D. BRANSON. "Evaluation of two different extubation criteria." Critical Care Medicine 14, no. 2 (1986): 92–94. http://dx.doi.org/10.1097/00003246-198602000-00003.

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5

Stocchetti, Nino, Luigi Beretta, and Giuseppe Citerio. "Criteria for extubation in neurologic patients." Critical Care Medicine 37, no. 4 (2009): 1529. http://dx.doi.org/10.1097/ccm.0b013e31819d2e62.

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Navalesi, Paolo, and Anna Levati. "Criteria for extubation in neurologic patients." Critical Care Medicine 37, no. 4 (2009): 1529–30. http://dx.doi.org/10.1097/ccm.0b013e31819d2f4e.

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7

Wang, Jing, Yingmin Ma, and Qiuhong Fang. "Extubation With or Without Spontaneous Breathing Trial." Critical Care Nurse 33, no. 6 (2013): 50–55. http://dx.doi.org/10.4037/ccn2013580.

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Purpose— To evaluate whether spontaneous breathing trials (SBTs) are necessary when extubating critical care patients. Methods— A prospective, randomized, double-blind study was performed in adult patients supported by mechanical ventilation for at least 48 hours in the general intensive care unit of a teaching hospital. Patients ready for weaning were randomly assigned to either the SBT group (extubation with an SBT) or the no-SBT group (extubation without an SBT). Patients in the SBT group who tolerated SBT underwent immediate extubation. Patients in the no-SBT group who met the weaning read
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8

Wong, Tiffany H., Garret Weber, and Apolonia E. Abramowicz. "Smooth Extubation and Smooth Emergence Techniques: A Narrative Review." Anesthesiology Research and Practice 2021 (January 15, 2021): 1–10. http://dx.doi.org/10.1155/2021/8883257.

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There is a paucity of literature on extubation technique and a lack of consensus regarding the definition of smooth extubation. This narrative review paper defines an ideal extubation, otherwise known as a “smooth extubation,” reviews perioperative criteria for extubation and risks and adverse events related to extubation, and explores various perioperative techniques that can be used to achieve a smooth extubation while caring for an uncomplicated patient without significant risk factors for extubation failure. In light of the evolving practice during the SARS CoV2 (COVID-19) pandemic to mini
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Ohtsuka, Masahide. "Extubation criteria of the tracheal tube in adults." Journal of the Japanese Society of Intensive Care Medicine 19, no. 3 (2012): 340–45. http://dx.doi.org/10.3918/jsicm.19.340.

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10

Zulian, Michaela, Jim W. Chisum, Edward L. Mosby, and W. Robert Hiatt. "Extubation criteria for oral and maxillofacial surgery patients." Journal of Oral and Maxillofacial Surgery 47, no. 6 (1989): 616–20. http://dx.doi.org/10.1016/s0278-2391(89)80078-3.

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Hennes, Hans J., Matthias David, Joern Oeltze, Matthias Schäfer, and Wolfgang F. Dick. "708 Safety Issues Regarding Early Extubation after Elective Craniotomy – A Prospective Evaluation of Extubation Criteria." Journal of Neurosurgical Anesthesiology 11, no. 4 (1999): 325. http://dx.doi.org/10.1097/00008506-199910000-00100.

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12

Steidl, Corinna, Julian Boesel, Sonja Suntrup-Krueger, et al. "Tracheostomy, Extubation, Reintubation: Airway Management Decisions in Intubated Stroke Patients." Cerebrovascular Diseases 44, no. 1-2 (2017): 1–9. http://dx.doi.org/10.1159/000471892.

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Background: Both delayed and premature extubation increase complication rate, the need for tracheostomy (TT), the duration of intensive care unit stay, and mortality. In this study, we therefore investigated factors associated with primary TT and predictors for extubation failure (EF) in a sample of severely affected ventilated stroke patients. Methods: One hundred eighty five intubated stroke patients were prospectively analyzed in this observational study. Patients not meeting predefined clinical and respiratory extubation criteria received a TT. All other patients were extubated and followe
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Maloney, Jillian, Bhavesh Patel, Linda Staley, Amelia Lowell, Dawn Jaroszewski, and Francisco Arabia. "Extubation Criteria for Patients With Total Artificial Heart (TAH)." Chest 142, no. 4 (2012): 405A. http://dx.doi.org/10.1378/chest.1386035.

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14

Khan, Nadeem, Shekhar Venkataraman, and Andrew Brown. "CRITERIA THAT PREDICT EXTUBATION SUCCESS IN MECHANICALLY VENTILATED CHILDREN." Critical Care Medicine 23, Supplement (1995): A225. http://dx.doi.org/10.1097/00003246-199501001-00395.

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15

Gilbert, Ralph W., Jeff C. McIlwain, Douglas P. Bryce, and Ian R. Ross. "Management of Patients with Long-Term Tracheotomies and Aspiration." Annals of Otology, Rhinology & Laryngology 96, no. 5 (1987): 561–64. http://dx.doi.org/10.1177/000348948709600516.

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The purpose of this study was to develop a management protocol for patients with long-term tracheotomies and aspiration, in order to develop clinical criteria for extubation and reduction of aspiration-related complications. We studied 39 patients with tracheotomies in place for over 3 months, 28 of whom completed management. Patients were classified according to degree of impairment and managed with the aims of avoiding aspiration and performing extubation whenever feasible. Criteria for choosing various management strategies are presented.
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Johnny, Jace D. "Readiness Assessment for Extubation Planning in the Intensive Care Unit: A Quality Improvement Initiative." Critical Care Nurse 41, no. 3 (2021): 42–48. http://dx.doi.org/10.4037/ccn2021912.

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Background Extubation failure is the reintubation of patients meeting criteria for weaning from mechanical ventilation. Extubation failure is correlated with mortality, prolonged mechanical ventilation, and longer hospital stays. Noninvasive ventilation or high-flow nasal cannula oxygen therapy after extubation is recommended to prevent extubation failure in high-risk patients. Local Problem The extubation failure rate is unknown. Prophylactic measures (noninvasive ventilation or high-flow nasal cannula) after extubation are not commonly used and vary among clinicians. The objective was to ass
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Ito, K., Z. Simons, C. I. Anderson, et al. "Postoperative Extubation in Head and Neck Surgery Patients: Risk Factors for Failure and Proposal for Extubation Criteria." Journal of Surgical Research 186, no. 2 (2014): 687. http://dx.doi.org/10.1016/j.jss.2013.11.1002.

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18

Rizzo, Julie A., Ryan McMahon, James K. Aden, Daniel B. Brillhart, and Leopoldo C. Cancio. "510 Incidence of Extubation Failure in a Burn Intensive Care Unit: Examination of Contributing` Factors." Journal of Burn Care & Research 41, Supplement_1 (2020): S91—S92. http://dx.doi.org/10.1093/jbcr/iraa024.142.

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Abstract Introduction Extubation failure is associated with negative outcomes making the identification of risk factors for failure paramount to patient selection. Burn patients experience a high incidence of respiratory failure requiring mechanical ventilation. There is no consensus on the acceptable rate of extubation failure and many conventional indices used in critical care do not accurately predict extubation outcome in burn patients. The purpose of this study was to examine the rate of extubation failure in the burned population and to examine the impact of inhalation injury, as well as
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19

Souter, M. J., and Edward M. Manno. "Ventilatory Management and Extubation Criteria of the Neurological/Neurosurgical Patient." Neurohospitalist 3, no. 1 (2012): 39–45. http://dx.doi.org/10.1177/1941874412463944.

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20

Ibrahimoglu, Ozlem. "Intraoperative variables associated with extubation time in patients undergoing open heart surgery." New Trends and Issues Proceedings on Humanities and Social Sciences 4, no. 2 (2017): 237–44. http://dx.doi.org/10.18844/prosoc.v4i2.2753.

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Decreasing mechanical ventilation and early extubation in patients has many clinical benefits. Hence, an awareness of some variables, associated with extubation time can help nurses to plan convenient care aimed at making a safe and early extubation. The purpose of this study was to investigate whether any intraoperative variables had a significant effect on extubation time following open heart surgery. The research was conducted on 60 open heart surgery patients who met inclusion criteria between April 2014 and November 2014 in a cardiac and vasculer surgery clinic of university hospital in I
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Swenker, Dominique, Anna van der Knijff-van Dortmont, Antonia Gonzalez Candel, Claudia Keyzer-Dekker, and Lonneke Staals. "Neuromuscular Blocking Agents and Rapid Sequence Induction for Laparoscopic Pyloromyotomy: Impact on Time to Extubation and Perioperative Complications." European Journal of Pediatric Surgery 30, no. 05 (2019): 440–46. http://dx.doi.org/10.1055/s-0039-1692656.

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Abstract Introduction Infants with hypertrophic pyloric stenosis have gastric outlet obstruction, indicating a pyloromyotomy. To prevent aspiration, a rapid sequence induction (RSI) of anesthesia used to be preferred. However, due to concerns about the side-effects of this technique in infants, a modified RSI with gentle mask ventilation is nowadays mostly used. This research investigates if induction with succinylcholine (classic RSI), cisatracurium (modified RSI), or no neuromuscular blocking agent (NMBA) influences time until extubation and incidence of complications in infants undergoing l
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Manno, Edward M., Alejandro A. Rabinstein, Eelco FM Wijdicks, et al. "A prospective trial of elective extubation in brain injured patients meeting extubation criteria for ventilatory support: a feasibility study." Critical Care 12, no. 6 (2008): R138. http://dx.doi.org/10.1186/cc7112.

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23

Maddali, Madan Mohan, Prakash Veru Matreja, and Mamie Zachariah. "Bispectral Index-Monitored Anesthesia Technique for Transsternal Thymectomy." Asian Cardiovascular and Thoracic Annals 17, no. 4 (2009): 389–94. http://dx.doi.org/10.1177/0218492309338120.

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To evaluate the role of bispectral index monitoring as an adjunct to balanced anesthesia in patients with myasthenia gravis undergoing transsternal thymectomy without the use of neuromuscular blocking agents, 10 patients were enrolled into this prospective observational study. After oral midazolam premedication, general anesthesia was induced with fentanyl, propofol, and sevoflurane. Tracheal intubation was performed without neuromuscular blocking agents. During maintenance, continuous monitoring of physiological and bispectral index parameters was used to titrate the doses of remifentanil, pr
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24

Kunikkakath, Shamjith, Shabeel Aboobacker C P, Melbin Baby, and Salman Mohammed Kutty C. "Effect of dexmedetomidine on hemodynamic and recovery responses during tracheal extubation." Indian Journal of Clinical Anaesthesia 8, no. 2 (2021): 310–15. http://dx.doi.org/10.18231/j.ijca.2021.057.

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Endotracheal extubation is associated with cardiovascular and airway responses leading to tachycardia, hypertension, arrhythmias, myocardial ischemia, coughing, agitation, bronchospasm, increased bleeding, raised intracranial and intraocular pressure which may be life threatening especially in vulnerable patients. Dexmedetomidine, a highly selective α2-adrenoreceptor agonist is found to attenuate these effects and provide a smooth extubation. To assess the effect of dexmedetomidine on hemodynamic and ventilatory recovery during tracheal extubation. This comparative study was done in 42 patient
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Keyal, Niraj Kumar, Roshana Amatya, Gentle Sunder Shrestha, Subash Prasad Acharya, Pramesh Sunder Shrestha, and Modh Nath Marhatta. "Influence of Arterial Blood Gas to Guide Extubation in Intensive Care Unit Patients after Spontaneous Breathing Trial." Journal of Nepal Health Research Council 18, no. 1 (2020): 21–26. http://dx.doi.org/10.33314/jnhrc.v18i1.2114.

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Background: Arterial blood gas is required for extubation decision after spontaneous breathing trial in most of intensive care unit. This study was conducted to assess the influence of arterial blood gas for extubation after successful spontaneous breathing trial in intensive care unit patients planned for extubation.Methods: It was prospective observation study conducted in all patients of age greater than eighteen year admitted in intensive care unit of tertiary care hospital for one year. It was done in 108 patients who were planned for extubation. Patients were assessed by intensivist clin
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Kansal, Amit, Shekhar Dhanvijay, Andrew Li, et al. "Predictors and outcomes of high-flow nasal cannula failure following extubation: A multicentre observational study." Annals of the Academy of Medicine, Singapore 50, no. 6 (2021): 467–73. http://dx.doi.org/10.47102/annals-acadmedsg.2020564.

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Introduction: Despite adhering to criteria for extubation, up to 20% of intensive care patients require re-intubation, even with use of post-extubation high-flow nasal cannula (HFNC). This study aims to identify independent predictors and outcomes of extubation failure in patients who failed postextubation HFNC. Methods: We conducted a multicentre observational study involving 9 adult intensive care units (ICUs) across 5 public hospitals in Singapore. We included patients extubated to HFNC following spontaneous breathing trials. We compared patients who were successfully weaned off HFNC with t
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Godard, Stephanie, Christophe Herry, Paul Westergaard, et al. "Practice Variation in Spontaneous Breathing Trial Performance and Reporting." Canadian Respiratory Journal 2016 (2016): 1–10. http://dx.doi.org/10.1155/2016/9848942.

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Background. Spontaneous breathing trials (SBTs) are standard of care in assessing extubation readiness; however, there are no universally accepted guidelines regarding their precise performance and reporting.Objective. To investigate variability in SBT practice across centres.Methods. Data from 680 patients undergoing 931 SBTs from eight North American centres from the Weaning and Variability Evaluation (WAVE) observational study were examined. SBT performance was analyzed with respect to ventilatory support, oxygen requirements, and sedation level using the Richmond Agitation Scale Score (RAS
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Neskovic, Vojislava, Predrag Milojevic, Dragana Unic-Stojanovic, Ivan Ilic, and Zoran Slavkovic. "High thoracic epidural anesthesia in patients with synchronous carotid endarterectomy and off-pump coronary artery revascularization." Vojnosanitetski pregled 70, no. 12 (2013): 1132–37. http://dx.doi.org/10.2298/vsp1312132n.

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Background/Aim. In order to reduce the risk of cerebrovascular insults (CVI), the latest recommendations suggest that carotid endarterectomy (CEA) is strongly indicated in patients scheduled for coronary surgery when significant carotid artery stenosis is symptomatic and/or bilateral. The best results are obtained in small studies with CEA performed immediately prior to off-pump coronary bypass (OPCAB). We present 16 consecutive patients who underwent synchronous CEA and OPCunder general anesthesia combined with high thoracic epidural anesthesia (TEA) in order to evaluate the safety and potent
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Cheng, Davy C. H., Jacek Karski, Charles Peniston, et al. "Early Tracheal Extubation after Coronary Artery Bypass Graft Surgery Reduces Costs and Improves Resource Use." Anesthesiology 85, no. 6 (1996): 1300–1310. http://dx.doi.org/10.1097/00000542-199612000-00011.

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Background Economics has caused the trend of early tracheal extubation after cardiac surgery, yet no prospective randomized study has directly validated that early tracheal extubation anesthetic management decreases costs when compared with late extubation after cardiac surgery. Methods This prospective, randomized, controlled clinical trial was designed to evaluate the cost savings of early (1-6 h) versus late tracheal extubation (12-22 h) in patients after coronary artery bypass graft (CABG) surgery. The total cost for the services provided for each patient was determined for both the early
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COPLIN, WILLIAM M, DAVID J PIERSON, KATHY D COOLEY, DAVID W NEWELL, and GORDON D RUBENFELD. "Implications of Extubation Delay in Brain-Injured Patients Meeting Standard Weaning Criteria." American Journal of Respiratory and Critical Care Medicine 161, no. 5 (2000): 1530–36. http://dx.doi.org/10.1164/ajrccm.161.5.9905102.

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31

Bach, John R., and Lou R. Saporito. "Criteria for Extubation and Tracheostomy Tube Removal for Patients With Ventilatory Failure." Chest 110, no. 6 (1996): 1566–71. http://dx.doi.org/10.1378/chest.110.6.1566.

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32

Georgiev, Stanimir, Gunter Balling, Bettina Ruf, et al. "Early postoperative extubation of unstable patients following total cavopulmonary connection: impact on circulation and outcome." Cardiology in the Young 27, no. 5 (2016): 860–69. http://dx.doi.org/10.1017/s1047951116001402.

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AbstractObjectivesWe aimed to investigate whether early postoperative extubation following the Fontan operation is universally feasible and can be used as a management tool in unstable patients.MethodsAll patients undergoing the Fontan operation in our centre between 2004 and 2013 (n=253) were analysed. Until 2008, patients were extubated according to standard criteria and comprised group 1. Group 2 included all patients presenting after 2009, when early extubation was always aimed regardless of the haemodynamic status. Patients who exceeded the 75th percentiles for volume requirements and ino
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Maharramova, Malak, and Katherine Taylor. "A Systematic Review of Caudal Anesthesia and Postoperative Outcomes in Pediatric Cardiac Surgery Patients." Seminars in Cardiothoracic and Vascular Anesthesia 23, no. 2 (2018): 237–47. http://dx.doi.org/10.1177/1089253218801966.

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Objectives. In pediatric cardiac surgery, does caudal anesthesia promote early extubation, reduce pain scores, reduce stress responses, and length of stay (LOS)? Design. A systematic review. Participants. Inclusion criteria included cardiac surgical procedures (with or without cardiopulmonary bypass) in any subject between the ages of full-term newborn and 18 years receiving caudal anesthesia of any medication combination. Searches were conducted with assistance of an Academic librarian from 1947 to July 2017. Methods. Relevant studies selected were randomized trials or cohort studies. Results
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Neskovic, Vojislava, Predrag Milojevic, Dragana Unic, Ivan Ilic, and Nada Popovic. "Early axtubation in cardiac surgery." Medical review 63, no. 3-4 (2010): 183–87. http://dx.doi.org/10.2298/mpns1004183n.

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Introduction An early extubation in cardiac surgery (fast track cardiac anesthesia) refers to mechanical ventilation during 1-6 hours after the intervention, the extubation criteria being the same as for any other surgery. Different protocols have been established for managing patients undergoing fast track anesthesia, with high-thoracic epidural anesthesia being increasingly used in the last few years. Material and methods Thirty-five consecutive patients scheduled for OPCAB surgery, who were planned for very fast track cardiac anesthesia (planned extubation within one hour after the end of t
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Gross, SB. "Early extubation: preliminary experience in the cardiothoracic patient population." American Journal of Critical Care 4, no. 4 (1995): 262–66. http://dx.doi.org/10.4037/ajcc1995.4.4.262.

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BACKGROUND: Changing trends and economic forces that emphasize reduced length of stay and early discharge have commanded the need for redesign in the perioperative management of cardiovascular surgical patients. In an effort to explore alternative strategies a multidisciplinary group developed an early extubation program. OBJECTIVES: To determine the safety and efficacy of early extubation in terms of patient outcome, satisfaction and psychologic recovery, and cost and resource utilization. METHODS: A prospective analysis was conducted on patients who met eligibility criteria. Data were acquir
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Biancofiore, G. "Very early tracheal extubation without predetermined criteria in a liver transplant recipient population." Liver Transplantation 7, no. 9 (2001): 777–82. http://dx.doi.org/10.1053/jlts.2001.23785.

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Marupudi, Neelima, Martina Steurer, and Deborah Franzon. "1188: COMPARISON OF INTENSIVIST ASSESSMENT OF EXTUBATION READINESS WITH WIDELY ACCEPTED OBJECTIVE CRITERIA." Critical Care Medicine 48, no. 1 (2020): 572. http://dx.doi.org/10.1097/01.ccm.0000643676.82644.c1.

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&NA;. "CRITERIA FOR TRACHAEL EXTUBATION OF PEDIATRIC LIVER TRANSPLANT PATIENTS IN THE OPERATING ROOM." Transplantation 82, Suppl 2 (2006): 547. http://dx.doi.org/10.1097/00007890-200607152-01427.

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Chu, R. F., A. V. Scott, and N. R. Wright. "Failure to meet extubation criteria in the setting of suspected buffalo chest physiology." Anaesthesia Reports 9, no. 1 (2021): 32–36. http://dx.doi.org/10.1002/anr3.12095.

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Baptistella, Antuani Rafael, Laura Maito Mantelli, Leandra Matte, et al. "Prediction of extubation outcome in mechanically ventilated patients: Development and validation of the Extubation Predictive Score (ExPreS)." PLOS ONE 16, no. 3 (2021): e0248868. http://dx.doi.org/10.1371/journal.pone.0248868.

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Despite the best efforts of intensive care units (ICUs) professionals, the extubation failure rates in mechanically ventilated patients remain in the range of 5%–30%. Extubation failure is associated with increased risk of death and longer ICU stay. This study aimed to identify respiratory and non-respiratory parameters predictive of extubation outcome, and to use these predictors to develop and validate an “Extubation Predictive Score (ExPreS)” that could be used to predict likelihood of extubation success in patients receiving invasive mechanical ventilation (IMV). Derivation cohort was comp
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A., Sudheer K., Sunil B., P. K. Rajiv, Mathew Kripail, and E. Nithya. "Volume guarantee ventilation in premature neonates with respiratory distress: a comparative study." International Journal of Contemporary Pediatrics 6, no. 6 (2019): 2559. http://dx.doi.org/10.18203/2349-3291.ijcp20194734.

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Background: Respiratory distress syndrome (RDS) occurs in about 50% of preterm infants born at less than 30 weeks of gestational age. Surfactant therapy and mechanical ventilation have been the standard of care in the management of RDS. Objective of this study to compare the time required to achieve successful extubation criteria in Volume guarantee mode of ventilation to that with Time cycled pressure-limited mode of ventilation and the duration of mechanical ventilation between them in preterm neonates ventilated for respiratory distress syndrome.Method: The study was done at Neonatal intens
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Huon, C., G. Moriette, P. Mussat, S. Parat, and J. P. Relier. "Use of Preestablished Criteria for Deciding on Extubation in the Very Low Birthweight Newborn." Neonatology 63, no. 2 (1993): 75–79. http://dx.doi.org/10.1159/000243913.

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Kuci, Saimir, Alfred Ibrahimi, Ermal Likaj, et al. "The Benefits of early Extubation in OR and ICU after Cardiac Surgery." Albanian Journal of Trauma and Emergency Surgery 5, no. 1 (2021): 765–68. http://dx.doi.org/10.32391/ajtes.v5i1.169.

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Objective: Operating room (OR) extubation after adult cardiac surgery with cardiopulmonary bypass CPB is rare. We examined the outcome, factors, and benefits of OR extubation.
 Methods: We operated on 60 patients in German Hospital Tirana, from January 2019 to September 2020, who had undergone CABG cardiac operations: 52 patients, mitral valve repair 5 patients, aortic stenosis 1patient, Bentall procedure 1 patient, left atrial myxoma 1 patient. The patient's age was from 46-82 years old, there were 24 female patients and 36 male patients, 24 diabetic patients, 36 non-diabetic patients, i
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Thille, Arnaud W., Grégoire Muller, Arnaud Gacouin, et al. "High-flow nasal cannula oxygen therapy alone or with non-invasive ventilation during the weaning period after extubation in ICU: the prospective randomised controlled HIGH-WEAN protocol." BMJ Open 8, no. 9 (2018): e023772. http://dx.doi.org/10.1136/bmjopen-2018-023772.

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IntroductionRecent practice guidelines suggest applying non-invasive ventilation (NIV) to prevent postextubation respiratory failure in patients at high risk of extubation failure in intensive care unit (ICU). However, such prophylactic NIV has been only a conditional recommendation given the low certainty of evidence. Likewise, high-flow nasal cannula (HFNC) oxygen therapy has been shown to reduce reintubation rates as compared with standard oxygen and to be as efficient as NIV in patients at high risk. Whereas HFNC may be considered as an optimal therapy during the postextubation period, HFN
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Faruq, Mohammad Omar, ASM Areef Ahsan, Kaniz Fatema, et al. "A Survey of Mechanical Ventilation Weaning Practices in ICUs of Bangladesh." Bangladesh Critical Care Journal 9, no. 1 (2021): 4–11. http://dx.doi.org/10.3329/bccj.v9i1.53049.

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Objective : To determine mechanical ventilation discontinuation (weaning) practices in Bangladesh as there is currently no data available on this issue.
 Method : Analyzing the Survey on Bangladeshi respondents using questionnaire developed by and used by a pan Asian study where Bangladesh critical care physicians participated.
 Result : 40 physicians from 10 ICUs of Bangladesh participated. Majority of our participating doctors (62.5%) came from private for profit hospital. 19 out of 40 respondents were certified in critical care medicine. In our study spontaneous breathing trial (S
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Gonzalez, Carlos, James S. Reilly, Margaret A. Kenna, and Ann E. Thompson. "Duration of Intubation in Children with Acute Epiglottitis." Otolaryngology–Head and Neck Surgery 95, no. 4 (1986): 477–81. http://dx.doi.org/10.1177/019459988609500410.

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Nasotracheal intubation has been demonstrated to be effective in supporting the airways of children with acute epiglottitis. Length of intubation and criteria used for extubation are still controversial. A 6-year retrospective review at Children's Hospital of Pittsburgh identified 100 cases of acute epiglottitis, which were initially managed with nasotracheal intubation. Extubation was based on direct laryngeal inspection performed in the operating room (1979–1981) and, more recently, in the intensive care unit (1982–1984). Length of intubation decreased from 63.8 hours in 1979 to 42.1 hours i
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47

Davies, Kylie, Max K. Bulsara, Anne-Sylvie Ramelet, and Leanne Monterosso. "Audit of Endotracheal Tube Suction in a Pediatric Intensive Care Unit." Clinical Nursing Research 26, no. 1 (2016): 68–81. http://dx.doi.org/10.1177/1054773815598272.

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We report outcomes of a clinical audit examining criteria used in clinical practice to rationalize endotracheal tube (ETT) suction, and the extent these matched criteria in the Endotracheal Suction Assessment Tool(ESAT)©. A retrospective audit of patient notes ( N = 292) and analyses of criteria documented by pediatric intensive care nurses to rationalize ETT suction were undertaken. The median number of documented respiratory and ventilation status criteria per ETT suction event that matched the ESAT© criteria was 2 [Interquartile Range (IQR) 1-6]. All criteria listed within the ESAT© were do
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48

Ali, Liaquat, Amim Akhter, Muhammad Saeed, Usman Khalid, and Jawad Rehmani. "COMPARISON OF INTRAVENOUS LIGNOCAINE VS NALBUPHINE IN ATTENUATION OF HEMODYNAMIC RESPONSE TO AWAKE TRACHEAL EXTUBATION IN ENT SURGERIES." PAFMJ 71, Suppl-1 (2021): S37–41. http://dx.doi.org/10.51253/pafmj.v71isuppl-1.2355.

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Objective: To compare intravenous lignocaine vs. intravenous nalbuphine in terms of mean change in heart rate and mean arterial pressures (MAP) during awake tracheal extubation.
 Study Design: Randomized control trial.
 Place and Duration of Study: Main Operation Theatre, Combined Military Hospital Rawalpindi, from May 2016to Dec 2016.
 Methodology: After approval of the study by the institution’s research ethics committee, the patients meetinginclusion criteria were assigned randomly to one of the two groups by lottery method. On return of spontaneous ventilation, patients in g
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49

Sulzer, Christopher F., René Chioléro, Pierre-Guy Chassot, Xavier M. Mueller, and Jean-Pierre Revelly. "Adaptive Support Ventilation for Fast Tracheal Extubation after Cardiac Surgery." Anesthesiology 95, no. 6 (2001): 1339–45. http://dx.doi.org/10.1097/00000542-200112000-00010.

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Background Adaptive support ventilation (ASV) is a microprocessor-controlled mode of mechanical ventilation that maintains a predefined minute ventilation with an optimal breathing pattern (tidal volume and rate) by automatically adapting inspiratory pressure and ventilator rate to changes in the patient's condition. The aim of the current study was to test the hypothesis that a protocol of respiratory weaning based on ASV could reduce the duration of tracheal intubation after uncomplicated cardiac surgery ("fast-track" surgery). Methods A group of patients being given ASV (group ASV) was comp
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50

Berton, Alessandro Maria, Filippo Gatti, Federica Penner, et al. "Early Copeptin Determination Allows Prompt Diagnosis of Post-Neurosurgical Central Diabetes Insipidus." Neuroendocrinology 110, no. 6 (2019): 525–34. http://dx.doi.org/10.1159/000503145.

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Introduction: Central diabetes insipidus (CDI) is a frequent complication of pituitary surgery, but its diagnosis lacks standardized criteria. Copeptin, a surrogate marker of arginine vasopressin release, is triggered by psycho-physical stresses such as pituitary surgery. Low postoperative copeptin could predict CDI onset. The aims of this study were the validation of copeptin as a predictor of post-neurosurgical CDI and the identification of the optimal timing for its determination. Methods: Sixty-six consecutive patients operated for a hypothalamic-pituitary lesion were evaluated. Copeptin w
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