Academic literature on the topic 'F-111s'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'F-111s.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "F-111s"

1

Feng, Ruize, Bo Wang, Shurui Cao, Tong Liu, Yongbo Su, Wuchang Ding, Peng Ding, and Zhi Jin. "Impact of symmetric gate-recess length on the DC and RF characteristics of InP HEMTs." Chinese Physics B 31, no. 1 (January 1, 2022): 018505. http://dx.doi.org/10.1088/1674-1056/ac364d.

Full text
Abstract:
Abstract We fabricated a set of symmetric gate-recess devices with gate length of 70 nm. We kept the source-to-drain spacing (L SD) unchanged, and obtained a group of devices with gate-recess length (L recess) from 0.4 μm to 0.8 μm through process improvement. In order to suppress the influence of the kink effect, we have done SiN X passivation treatment. The maximum saturation current density (I D_max) and maximum transconductance (g m,max) increase as L recess decreases to 0.4 μm. At this time, the device shows I D_max=749.6 mA/mm at V GS=0.2 V, V DS=1.5 V, and g m_max=1111 mS/mm at V GS=−0.35 V, V DS=1.5 V. Meanwhile, as L recess increases, it causes parasitic capacitance C gd and g d to decrease, making f max drastically increases. When L recess = 0.8 μm, the device shows f T=188 GHz and f max=1112 GHz.
APA, Harvard, Vancouver, ISO, and other styles
2

Carlyle, J. M. "Acoustic emission testing the F-111." NDT International 22, no. 2 (April 1989): 67–73. http://dx.doi.org/10.1016/0308-9126(89)90859-6.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Carlyle, J. "Acoustic emission testing the F-111." NDT & E International 22, no. 2 (April 1989): 67–73. http://dx.doi.org/10.1016/0963-8695(89)90158-8.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Lichovníková, Martina, and Alžbeta Jarošová. "The effect of genotype and age on the carcass quality of broilers and males of the laying hybrids." Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis 56, no. 4 (2008): 121–26. http://dx.doi.org/10.11118/actaun200856040121.

Full text
Abstract:
In the study the carcass quality of fast growing broilers (F) and slow growing layer males (S) was compared. The effect of age on the carcass quality of S (S1, S2) was also evaluated. The weights of the carcasses were as follows: F 1110 g, S at 90 days of age 1116 g (S1) and S at the age of 132 days 1878 g (S2). Despite similar carcass weight in F and S1, the weight of the breast, and it’s proportion to the total body weight was significantly higher (P < 0.001) in F (265 g and 23.9% vs. S1 174 g and 15.6%). Continued fattening of the layer males resulted in increased breast weight (S2 276 g, P < 0.001) but not in breast proportion (S2 14.7%).The weight of the legs was significantly higher (P < 0.001) in S1 in comparison with F, but it was due to the heavier weight of the leg bones in S1 (P < 0.001). There was no difference neither in the weight of the leg muscles, nor of the leg proportions between F and S1. The proportion of the leg muscles increased significantly (P < 0.05) in S2 (25.6%) in comparison with S1 (24.1%). The content of abdominal fat, fat in the breast and fat in the leg muscles was significantly lower (P < 0.01, P < 0.01, P < 0.05, respectively) in the layer males S1 in comparison with the F broilers. The proportion of abdominal fat was 1.79% in F, and 0.54% in S1. The content of the breast fat was 1.24% in F and 0.56% in S1. The proportion of fat in the leg muscles was 8.45% in F and 2.78% in S1. As the birds became older, the content of the fat increased: the abdominal fat in S2 – 1.38% (P < 0.01), the breast fat in S2 – 0.96% (P < 0.01) and the leg muscles fat in S2 – 3.94% (P < 0.05). There was significantly lower (P < 0.001) content of dry matter in S1 than in F both in the breast and in the leg muscles.At the same carcass weight as the broilers, the layer males had a lower proportion of breast meat and also a lower content of abdominal fat, fat in the breast and fat in the leg muscles. The proportion of the leg muscles was comparable between the two groups. Concerning meat production, the quality of the carcasses of the layer males improved with age. Comparing the F carcasses with weight at 1110 g with the S2 carcass with weight of 1878 g, the weigh of the breast was almost the same, the weight of the leg muscles was higher in S2, and mainly the content of the fat in leg muscles was lower. The content of the abdominal fat and the breast fat was similar in both groups.
APA, Harvard, Vancouver, ISO, and other styles
5

Pasti, Igor, Nemanja Gavrilov, and Slavko Mentus. "Fluorine adsorption on transition metal surfaces: A DFT study." Journal of the Serbian Chemical Society 78, no. 11 (2013): 1763–73. http://dx.doi.org/10.2298/jsc130729095p.

Full text
Abstract:
On the basis of Density Functional Theory calculation, the adsorption of fluorine was investigated on a) Cu(111), Au(111), Pd(111) and Pt(111) surfaces, b) on Pd monolayer surfaces over Cu(111), Au(111) and Pt(111) surface, and c) on the surfaces of Pd(111) monocrystal with inserted metal monolayer (M = Cu, Au, Pt) underneath the first Pd surface layer. The results evidenced that the adsorption did not cause significant structural parameters of metallic substrate. The strongest adsorption amounting to -4.49 eV was calculated in the case of Cu(111) surface. The Cu(111) and Au(111) surface atoms interact with F adatoms by the mediation of sp-band exclusively, while the surface atoms of Pt and Pd-based surfaces interact with F adatoms additionally by the mediation of d-band, too. In the case of Pt(111) and PdML/M(111) surfaces, the binding energies are correlated with the d-band center positions, which indicated a significant contribution of covalent interaction. These results confirmed that the nature of surface interaction of highly electronegative F atom with metallic surfaces depends significantly on the nature of the metal substrate.
APA, Harvard, Vancouver, ISO, and other styles
6

Shaw, Leonard, Rodney Clark, and Dick Talmadge. "F-111 generic weapons bay acoustic environment." Journal of Aircraft 25, no. 2 (February 1988): 147–53. http://dx.doi.org/10.2514/3.45555.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

MACHIDA, Kenji, Kenji USUI, and Hiroyuki OKAMURA. "F-1114 Hybrid Stress Analysis System by Speckle Photography." Proceedings of the JSME annual meeting VI.01.1 (2001): 209–10. http://dx.doi.org/10.1299/jsmemecjo.vi.01.1.0_209.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

AOKI, Hiroyuki, Akira SHIMAMOTO, Katsunori FUTASE, and Yukihiko KAMADA. "F-1117 Impact Tensile Behavior of Liquid Packaging Bag." Proceedings of the JSME annual meeting VI.01.1 (2001): 215–16. http://dx.doi.org/10.1299/jsmemecjo.vi.01.1.0_215.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Schofield, Peter W., Richard Gibson, Meredith Tavener, John R. Attia, Catherine D’Este, Maya Guest, Anthony M. Brown, et al. "Neuropsychological health in F-111 aircraft maintenance workers." NeuroToxicology 27, no. 5 (September 2006): 852–60. http://dx.doi.org/10.1016/j.neuro.2006.02.002.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Wittman, Vaughan, and Jon Weidanz. "F.111. Tumor Cell Lysis Using TCR Mimics." Clinical Immunology 119 (January 2006): S89—S90. http://dx.doi.org/10.1016/j.clim.2006.04.151.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "F-111s"

1

Crouch, Viv, and Anna Goldstein. "A HIGH-DEMAND TELEMETRY SYSTEM THAT MAXIMISES FUTURE EXPANSION AT MINIMUM LIFE-CYCLE COST." International Foundation for Telemetering, 1994. http://hdl.handle.net/10150/608556.

Full text
Abstract:
International Telemetering Conference Proceedings / October 17-20, 1994 / Town & Country Hotel and Conference Center, San Diego, California
The Aircraft Research and Development Unit (ARDU) of the Royal Australian Air Force (RAAF) is the only agency in Australia that performs the full spectrum of military flight testing and is the new custodian of the instrumented weapons range at Woomera. Receiving early attention will be the upgrade and integration of ARDU's telemetry systems with the meteorological and tracking data acquisition capabilities at Woomera to minimize overhead and data turnaround time. To achieve these goals, maximum modularity, extensibility, and product interoperability is being sought in the proposed architecture of all the systems that will need to cooperate on the forecast test programmes. These goals are also driven by the need to be responsive to a wide variety of tasks which presently include structural flight testing of fighter and training aircraft, weapons systems performance evaluation on a variety of combatant aircraft, and a host of other tasks associated with all fixed and rotary wing aircraft in the Army and Air Force inventory. Of all these tasks however, ARDU sees that responsiveness to future testing of F-111Cs fitted with unique Digital Flight Control Systems along with USAF standard F-111Gs may place the most significant demands on data handling —particularly in regard to providing an avionics bus diagnostic capability when performing Operational Flight Programme (OFP) changes to the mission computers. With the timely assistance and advice of Loral Test & Information Systems, who has long-term experience in supporting USAF F-111 test programmes, ARDU is confident of making wise design decisions that will provide the desired flexibility and, at the same time, minimize life-cycle costs by ensuring compliance with the appropriate telemetry and open systems standards. As well, via cooperative agreements with the USAF, the potential exists to acquire proven software products without needing to fund the development costs already absorbed by the USAF. This paper presents ARDU's perception of future needs, a view by LTIS of how best to meet those needs, and, based on ARDU data, a view of how LTIS' proposal will satisfy the requirement to provide maximum extensibility with minimum life-cycle costs.
APA, Harvard, Vancouver, ISO, and other styles
2

Matos, Izabela Teles de. "Padronização dos radionuclídeos F-18 e In-111 e determinação dos coeficientes de conversão interna total para o In-111 em sistema de coincidência por software." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/85/85131/tde-28052014-155222/.

Full text
Abstract:
O presente trabalho descreve a metodologia para a padronização dos radionuclídeos 111In e 18F e a determinação dos Coeficientes de Conversão Interna do 111In em Sistema de Coincidência por Software (SCS). O 111In decai com uma meia-vida de 2,8 dias por processo de captura eletrônica seguido por emissão de raios gama concorrendo com os elétrons da conversão interna. O 18F é um emissor de pósitrons de meia-vida curta (1,8 h), usado em Medicina Nuclear. As soluções radioativas usadas neste trabalho foram fornecidas pelo Centro de Radiofarmácia do IPEN e as massas determinadas pela técnica do picnômetro. As medidas foram feitas utilizando o Sistema de Coincidência 4πβ-γ constituído por um contador proporcional de geometria 4π a gás fluente e um semicondutor HPGe, acoplado a este sistema foi utilizado um sistema digital denominado de SCS com vantagem de obtenção da curva de extrapolação em uma única medida. A atividade do 111In foi determinada pela técnica de extrapolação linear da eficiência do contador proporcional usando absorvedores externos em ambos os lados das fontes. Os valores dos Coeficientes de Conversão Interna Total foram determinados selecionando duas janelas de raios gama (175 keV e 245 keV). A atividade do 18F foi determinada pela técnica de extrapolação linear da eficiência do contador proporcional utilizando a discriminação eletrônica. O código de simulação Monte Carlo ESQUEMA versão 9 foi usado para simular a extrapolação da curva da eficiência do 18F, considerando as características do esquema de desintegração e todos os detalhes geométricos do sistema de detecção.
This paper describes the methodology for standardization of radionuclides 111In and 18F and the determination of Total Internal Coefficients of 111In by means of a software coincidence system (SCS). The 111In decays with a half-life of 2.8 days by the electron capture process followed by gamma rays emission competing with internal conversion electrons. The 18F is a positron emitter with a short halflife (1.8 h), used in Nuclear Medicine. The radioactive solutions were provided by the Center for Radiopharmacy IPEN and the masses determined by pycnometer technique. The measurements were made using a Coincidence System 4πβ-γ consisting of a proportional counter in 4π geometry fluent gas and a HPGe semiconductor, coupled to the system was used a digital system called SCS with the advantage of obtaining the extrapolation curve in a single measurement. The activity of 111In was achieved by means of the linear extrapolation technique of the proportional counter efficiency using external absorbers on both sides of the sources. The values of the Total Internal Coefficients were determined selecting the two windows of gamma rays (175 keV and 245 keV). The activity of 18F was determined by means of the linear extrapolation, using electronic discrimination. The Monte Carlo simulation code ESQUEMA version 9 was used to simulate the efficiency curve extrapolation of the 18F, considering the characteristics of the system, the decay scheme of disintegration and all geometric details of the detection system.
APA, Harvard, Vancouver, ISO, and other styles
3

MATOS, IZABELA T. de. "Padronização dos radionuclídeos F-18 e In-111 e determinação dos coeficientes de conversão interna total para o In-111 em sistema de coincidência por software." reponame:Repositório Institucional do IPEN, 2014. http://repositorio.ipen.br:8080/xmlui/handle/123456789/10615.

Full text
Abstract:
Made available in DSpace on 2014-10-09T12:42:28Z (GMT). No. of bitstreams: 0
Made available in DSpace on 2014-10-09T14:02:00Z (GMT). No. of bitstreams: 0
Dissertação (Mestrado)
IPEN/D
Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP
APA, Harvard, Vancouver, ISO, and other styles
4

Amblard-Larolphie, Isabelle. "Intérêt de l'immunoscintigraphie dans le diagnostic des récurrences des cancers colo-rectaux avec les fragments F (ab') d'un anticorps anti antigène carcino-embryonnaire marques à l'indium 111." Bordeaux 2, 1993. http://www.theses.fr/1993BOR23043.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Maita, Pedro Antonio. "Investigación de las características de adherencia sobre matrices de embutición de acero f-1110, y análisis mediante ensayos de emisión acústica, de recubrimientos de níquel-óxidos y carburos cerámicos aplicados por proyección térmica, y de las carac." Doctoral thesis, Universitat Politècnica de València, 2008. http://hdl.handle.net/10251/1924.

Full text
Abstract:
En los últimos cinco años la tecnología de los recubrimientos superficiales se ha incrementado. Al respecto se tienen avances en las propiedades superificiales de los amteriales influyendo en el campo de la competitividad, producción de calidades y surgimiento de técnicas de recubrimientos, dependiendo de la adaptabilidad, aplicación y costo. En la actualidad el campo de las matrices de embutición apunta al problema generado en el servicio, modificaciones de medidas, desgastes, impactos, deformaciones y proceso de fractura, causado por las altas tensiones cortantes en zonas de deslizamiento de la chapa con la matriz. No obstante se puede recuperar la matriz por desgaste prematuro en bordes y posibles fisuras. A nivel mundial, el problema ha sido estudiado, pero dada su complejidad en la búsqueda de lograr la calidad y la efeciencia en las condiciones de servicio de la matriz, se aplican sobre su superficie las siguientes tecnologías: procesos térmicos, tratamientos superficiales, desposiciones superficiales y técnicas en recuperación por desgaste y fisuras. En esta investigación se aplicó la proyección térmica por llama con uso de polvo como ténica en reparación, en virud de la importancia de alternativas de recuperación de matrices de embutición para complementar las tecnologías existentes, garantizánose la función destino de la matriz, antes de ser consumida durante las operaciones de trabajo en frío y caliente. La proyección térmica por llama es una alternativa de bajo costo, aventajada en aplicación de capas cerámicas para recuperación de zonas desgastadas en matrices. Un requerimiento principal es la adherencia del recubrimiento en el sustrato y no es fácil alcanzar valores apropiados dadas la naturaleza cerámica del recubrimiento y los cortos tiempos de aplicación. Para cuantificar la adherencia se ensayaron las probetas recubiertas con aleaciones cerámicas sometidas a esfuerzos de cizalladura, para lograr en la intercara el deslizamiento cortante del recubrim
Maita, PA. (2007). Investigación de las características de adherencia sobre matrices de embutición de acero f-1110, y análisis mediante ensayos de emisión acústica, de recubrimientos de níquel-óxidos y carburos cerámicos aplicados por proyección térmica, y de las carac [Tesis doctoral no publicada]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/1924
Palancia
APA, Harvard, Vancouver, ISO, and other styles
6

Guest, Maya. "The study of health outcomes in aircraft maintenance personnel: sensory system effects." Thesis, 2011. http://hdl.handle.net/1959.13/928178.

Full text
Abstract:
Research Doctorate - Doctor of Philosophy (PhD)
Introduction: The effects of workplace exposure to neurotoxins on the central nervous system are well documented, however the effects on senses is an emerging area. This thesis has examined the senses: hearing, balance, touch and colour vision in a group of aircraft maintainers from the Royal Australian Air Force who undertook deseal/reseal fuel tank maintenance on F-111 aircraft compared to two different control groups. This exposed group used formulations containing neurotoxins in the fuel tank deseal/reseal process. Methods: Study population: The study population consisted of three groups: F-111 deseal/reseal exposed personnel, technical-trade comparisons to assess different base, same job and non-technical comparisons to assess same base, different job. The study utilised a mailed postal questionnaire and a series of clinical assessments. As military personnel, this study population met minimum physical fitness requirements on enlistment. Clinical assessment: Hearing was assessed by measuring hearing thresholds of each ear at eight frequencies from 500 to 8000 Hz using pure-tone audiometry. The percentage loss of hearing was calculated. Balance was assessed by measuring functional reach. Touch was assessed by measuring vibration perception thresholds at distal extremities using biothesiometry. Colour vision was assessed using the Ishihara test plates and the Lanthony D-15 Desaturated colour disc arrangement test. Those who failed the Ishihara test were excluded from the analysis. From the Lanthony colour disc arrangement test results the type of colour deficient vision was diagnosed, and Bowman’s colour confusion index was calculated. Other risk factors: In the postal questionnaire and during the clinical examination a number of other risk factors were assessed: anxiety and depression were assessed using the composite International Diagnosis Interview, Kessler Psychological distress scale, height, weight, and visual acuity (using Snellen chart). From the postal questionnaire information on general health and well-being, alcohol intake, smoking history, existence of tinnitus, doctor diagnosed diabetes, medications regularly used and a civilian job history were obtained. Other risk factors included in all statistical modeling included age, posting category, rank and location of clinical assessment. Statistical methods: Regression models were used to examine whether there was an association between F-111 fuel tank maintenance and sensory impairments, adjusting for possible confounders. In addition multiple linear regressions were also used to determine whether any association exists between the functional reach and the auditory thresholds at the eight measured frequencies in both ears. Graphical comparison was made of the hearing thresholds at all eight frequencies with the published ISO-7029 medians. Results: The study population consisted of 614 exposed personnel, 513 technical-trade comparisons and 403 non-technical comparisons (numbers in each analysis differ slightly). The percentage loss of hearing ranged from nil to 96 (median 1.5, quartiles 0.3, 5.5). A logistic regression model showed no statistically significant difference in percentage loss of hearing among the three exposure groups (exposed verses non-technical controls OR 1.1: 95%CI 0.7, 2.0 and exposed verses technical OR 0.9: 95% CI 0.6, 1.3). However, at all eight frequencies measured, all populations had lower than expected hearing thresholds based on published ISO-7029 medians. The linear regression model showed that functional reach was slightly better for the comparison groups than the deseal/reseal group with only one group being statistically significant; however the difference was not clinically significant. The model did show that functional reach decreases significantly with age, anxiety and depression, whereas it improves with height. A significant association was found between vestibular function, measured by functional reach, and auditory thresholds at 500 and 1000 Hz, which were influenced by anxiety. Over 26% of all study participants had chronic persistent decreased vibration perception threshold in the great toe. Statistically significant higher vibration perception threshold of the great toe was observed in the comparison groups; this remained significant when vibration perception threshold was dichotomized into normal and abnormal categories; however the effect was small and about ¼ the magnitude of diabetes. Age, height and diabetes were all significant and stronger predictors in most models. Colour confusion index results ranged from 1 to 2.8 (median 1.2, quartiles 1.1, 1.4) in the 2600 eyes tested. Forty five percent of all study participants had blue-yellow colour deficient vision in at least one eye which is consistent with environmental exposures. Logistic regression demonstrated statistically significant differences in colour confusion index category in the exposed group versus technical group (OR 1.7: 95% CI 1.3-2.0) and a blue-yellow confusion in the exposed group versus technical group (OR 1.4: 95% CI 1.1-1.7). Discussion: This study has examined the effects of the deseal/reseal exposures and aircraft maintenance on four senses: hearing, balance, touch and colour vision. The hearing analysis showed that while the study participants had high levels of hearing loss in comparison to the published ISO7029 medians we did not observe any difference between the three exposure groups. The analysis for balance did show a difference with one of the exposure groups; however the difference was too small to be clinically significant. The analysis for touch did show that one quarter of all study participants had chronic persistent increased vibration perception threshold in the great toe and the analysis for colour vision indicated reduced colour discrimination among the exposed subjects compared to the Richmond controls. These findings are relatively weak in determining the effect of the deseal/reseal exposures on these senses. However, the comparison with normative data that were available (hearing and vibration perception) did show that the study population as a whole have higher hearing thresholds and higher vibration perception thresholds. In the absence of normative data for colour vision we observed almost one third of all participants had an abnormal colour confusion index or a blue-yellow deficit. These finding would suggest that whilst the deseal/reseal exposures to ototoxins and neurotoxins were high, a Royal Australian Air Force effect is also being observed. This statement can be made with some confidence as all military personnel are required to be physically fit and pass a stringent medical before enlistment. Study strengths and weaknesses: a strength is the number of study participants; 1538 participants were examined for the general health and medical assessment making the SHOAMP study one of the largest in the examination of sensory neuropathy. Another is that all outcomes reported were directly measured in the health examination; no self-reported data has been used. One caveat is the study was carried out retrospectively without exposure data for the substances used in the deseal/reseal programs. Conclusion: This thesis has compared a series of sensory outcomes in personnel involved in F-111 DSRS activities with two contemporaneous comparisons groups. It shows non-specific decrease in hearing due to Air Force wide exposures, likely noise, but it does show a specific decrease in colour vision probably due to deseal/reseal exposures.
APA, Harvard, Vancouver, ISO, and other styles
7

Qiu, Jian Ming, and 邱建銘. "studies on the alkaline lipase from pseudomonas pseudoalcaligenes F-111 strain." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/03220418238780954517.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Lee, Wei-yu, and 李韋佑. "Gene cloning and characterization of lipase chaperone from Pseudomonas pseudoalcaligenes F-111." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/72748685746065189946.

Full text
Abstract:
碩士
國立高雄大學
生命科學系碩士班
103
Escherichia coli is a commonly used gene transformation and protein production host in modern bioengineering. However, its Gram-negative double layer membrane structure also causes target protein aggregation in its periplasm space, leading to a result of inactive inclusion body formation. The aim of this study is to utilize a bacterial strain Pseudomonas pseudoalcaligenes F-111 to study its lipase chaperone’s characteristics of assisting lipase secretion. By utilizing PCR, both the lipase and lipase chaperone genes from F-111 were cloned and ligated with vector pGEM-3zf(+). The computer bioinformatics prediction showed the lipase polypeptide contains a signal peptide, a necessary for secretion. Meanwhile, the structure of lipase chaperone was predicted by homology modeling. Protein analysis showed the E. coli strain transformed with complete lipase and lipase chaperone genes express lipase activities. However, if the lipase chaperone gene is knocked out, despite SDS-PAGE still shows lipase expression, it did not express its activity as the E. coli strain transformed with complete lipase and lipase chaperone genes. In conclusion, the lipase chaperone gene cloned in this study plays a crucial role in lipase activity. The study expects the discovery would lead to constructing an expression vector with the lipase chaperone gene attached for it assisting target protein secreting, to improve the convenience of protein purification in future.
APA, Harvard, Vancouver, ISO, and other styles
9

Hsiao-Jung, Wu, and 吳曉蓉. "C-C Bond Formation and C-F Bond Activation on the Ag(111) Surface." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/91299292672584759006.

Full text
Abstract:
碩士
國立中山大學
化學研究所
86
The insertion of methylene (CH2) into the metal-alkyl bonds has been studied on Ag(111) surface under ultrahigh vacuum (UHV) conditions. The methyl (CH3) groups formed on Ag(111) by thermal dissociation of the C-Ibond in adsorbed methyl iodide (CH3I) below 200 K were coupled to produceethane (C2H6) around 250 K in temperature-programmed reaction (TPR) experiments. Similar low temperature C-I bond scissions in adsorbed methylene iodide (CH2I2) forming CH2(ad) was implicated based on the evolution of ethylene (C2H4) at 260 K in TPR. By studying the interaction of CH3(ad) and CH2(ad) coadsorbed on Ag(111), propane (C3H8) and butane (C4H10) were detected. It suggests that methylene was inserted into the Ag-CH3 bond to produce an ethyl (CH2CH3) group on Ag(111). In the presenceof methyl and ethyl groups, the fo;;owing self and cross coupling reactionsresulted in those longer-chain hydrocarbon compounds. In order to demonstratethe methylene insertion mechanism again, we used CF3 to substitute CH3 as thetarget for the methylene insertion. Trifluoromethyl iodide (CF3I) was used asa molecular precursor to generate adsorbed trifluoromethyl (CF3) fragments on Ag(111) surface. TPR studies of the CF3(ad) + CD2(ad) showed that CD2 was also inserted into the Ag-CF3 bond, however, followed by a simple termination step ,B-fluoride elimination, to produced 1,1-difluoroethylene-d2(CF2=CD2) in the gas phase. Two sequential methylene insertions were also implicated as evidencedby the production of 1,1,1-trifluoropropyl iodide - 2,3-d4 (CF3CD2CD2I) as aresult of the rcombination of CF3CD2CD2 with iodine. To our knowledge, this is the firat example of explicitly demonstrate the methylene insertion onAg(111) surface under ultrahigh vacuum conditions.
APA, Harvard, Vancouver, ISO, and other styles
10

Wang, Shing-Kuen, and 王興焜. "Photolysis Study of CF2Cl2 Adsorbed on Si(111)-7*7 Using Photons Near F(1s) Edge." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/13231874515361798855.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Books on the topic "F-111s"

1

Don, Greer, and Spraggins Matheu, eds. F-111 Aardvark. Carrollton, TX: Squadron Signal Publications, 2008.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
2

F-111 AARDVARK. London: Arms and Armour Press, 1989.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
3

Neubeck, Ken. F-111 Aardvark. Carrollton, TX: Squadron Signal Publications, 2008.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
4

Logan, Don. General Dynamics F-111 Aardvark. Atglen, PA: Schiffer Pub., 1998.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
5

Kinzey, Bert. F-111 Aardvark in detail & scale. Blue Ridge Summit, PA: TAB Books, 1988.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
6

F-111 Aardvark in detail & scale. Blue Ridge Summit, PA: TAB Books, 1989.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
7

E, Davies Peter, ed. F-111: Success in action. London: Arms & Armour, 1989.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
8

Coulam, Robert F. Illusions of choice: The F-111 and the problem of weapons acquisition reform. Washington, DC: Beard Books, 2000.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
9

McNess, Jan. Thirteenth night: A mother's story of the life and death of her son. Fremantle, W.A: Fremantle Arts Centre Press, 2003.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
10

Larson, Richard R. AFTI/F-111 MAW flight control system and redundancy management description. Edwards, Calif: National Aeronautics and Space Administration, Ames Research Center, Dryden Flight Research Facility, 1987.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Book chapters on the topic "F-111s"

1

Massuger, Leon F. A. G., Roland A. M. J. Claessens, Lambert G. Poels, René H. M. Verheijen, Charles P. T. Schijf, Frans H. M. Corstens, and Peter Kenemans. "Pharmacokinetics and Tissue Distribution of Indium-111-Labeled OV-TL 3 F(ab’)2 in Ovarian Cancer Patients." In From Clone to Clinic, 83–88. Dordrecht: Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-011-3780-5_10.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

"The F-111B and the Lineage of the F-14." In The Aircraft Designers: A Grumman Historical Perspective, 103–42. Reston ,VA: American Institute of Aeronautics and Astronautics, 2013. http://dx.doi.org/10.2514/5.9781624101786.0103.0142.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Marks II, Robert J. "Signal Recovery." In Handbook of Fourier Analysis & Its Applications. Oxford University Press, 2009. http://dx.doi.org/10.1093/oso/9780195335927.003.0015.

Full text
Abstract:
The literature on the recovery of signals and images is vast (e.g., [23, 110, 112, 257, 391, 439, 791, 795, 933, 934, 937, 945, 956, 1104, 1324, 1494, 1495, 1551]). In this Chapter, the specific problem of recovering lost signal intervals from the remaining known portion of the signal is considered. Signal recovery is also a topic of Chapter 11 on POCS. To this point, sampling has been discrete. Bandlimited signals, we will show, can also be recovered from continuous samples. Our definition of continuous sampling is best presented by illustration.Asignal, f (t), is shown in Figure 10.1a, along with some possible continuous samples. Regaining f (t) from knowledge of ge(t) = f (t)Π(t/T) in Figure 10.1b is the extrapolation problem which has applications in a number of fields. In optics, for example, extrapolation in the frequency domain is termed super resolution [2, 40, 367, 444, 500, 523, 641, 720, 864, 1016, 1099, 1117]. Reconstructing f (t) from its tails [i.e., gi(t) = f (t){1 − Π(t/T)}] is the interval interpolation problem. Prediction, shown in Figure 10.1d, is the problem of recovering a signal with knowledge of that signal only for negative time. Lastly, illustrated in Figure 10.1e, is periodic continuous sampling. Here, the signal is known in sections periodically spaced at intervals of T. The duty cycle is α. Reconstruction of f (t) from this data includes a number of important reconstruction problems as special cases. (a) By keeping αT constant, we can approach the extrapolation problem by letting T go to ∞. (b) Redefine the origin in Figure 10.1e to be centered in a zero interval. Under the same assumption as (a), we can similarly approach the interpolation problem. (c) Redefine the origin as in (b). Then the interpolation problem can be solved by discarding data to make it periodically sampled. (d) Keep T constant and let α → 0. The result is reconstructing f (t) from discrete samples as discussed in Chapter 5. Indeed, this model has been used to derive the sampling theorem [246]. Figures 10.1b-e all illustrate continuously sampled versions of f (t).
APA, Harvard, Vancouver, ISO, and other styles
4

"Plate 30 Distillation of perfumes and essences (f.111b)." In The Ni'matnama Manuscript of the Sultans of Mandu, 157. Routledge, 2004. http://dx.doi.org/10.4324/9780203330920-37.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

PAGAN, A. A. "UMA BIOLOGIA AFETIVA BASEADA NO AUTOCONHECIMENTO COMO POSSIBILIDADE DE INCLUSÃO DE GÊNEROS." In Interculturalidade e transdisciplinaridade: “o que a Biologia tem a ver com isso?”, 111–22. Navegando Publicações, 2021. http://dx.doi.org/10.29388/978-65-86678-66-6-f.111-122.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

"136 To Ralph Pilkington, Cadize 18 August 1756 [f. 111]." In Records of Social and Economic History: New Series, Vol. 28: Letterbook of Greg & Cunningham, 1756–57: Merchants of New York and Belfast, edited by Thomas M. Truxes. British Academy, 2001. http://dx.doi.org/10.1093/oseo/instance.00164148.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

CISLAGHI, J. F. "Financeirização, Ultraneoliberalismo e Política Social: impactos para o trabalho dos assistentes sociais." In Serviço Social em tempos ultraneoliberais, 111–26. Navegando Publicações, 2021. http://dx.doi.org/10.29388/978-65-81417-38-3-0-f.111-126.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

GAMA, Zacarias Jaegger. "A Formação de Profissionais de Educação no Brasil: entre o público e o privado." In Cenários políticos e pedagógicos, 111–32. Navegando Publicações, 2021. http://dx.doi.org/10.29388/978-65-86678-74-1-0-f.111-132.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

VALDO, J. P. "CAPITALISMO DEPENDENTE E A UNIVERSIDADE PÚBLICA BRASILEIRA: PARTICULARIDADES E DESAFIOS NO SÉCULO XXI." In Capitalismo dependente, racismo estrutural e educação brasileira: diálogos com Florestan Fernandes, 111–32. Navegando Publicações, 2020. http://dx.doi.org/10.29388/978-65-86678-36-9-0-f.111-132.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

PERES, Lúcia M. V. "Por entre gestos e dribles no tempo: o amor e o simbólico em pauta!" In Imaginar: uma constelação de estudos sob a ótica do imaginário, 11–126. Navegando Publicações, 2019. http://dx.doi.org/10.29388/978-65-81417-00-0-0-f.111-126.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "F-111s"

1

Zhang, Yuxiang, Ryan Buntain, Jacob Edwards, Boian Alexandrov, and Jorge A. Penso. "Evaluation of Susceptibility to Thermal Fatigue Cracking in High Temperature Alloys for Refinery Olefin Applications." In ASME 2020 Pressure Vessels & Piping Conference. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/pvp2020-21741.

Full text
Abstract:
Abstract High carbon, Cr – Ni alloys are used for tubing in refinery olefin furnaces. During furnace operation, such tubes might be exposed to thermal shock and fatigue loading, which may result in cracking and/or complete rupture. The objective of this study was to develop and validate a testing procedure for evaluation and ranking the susceptibility to thermal fatigue cracking in tubing of such Cr – Ni alloys. The proposed thermal fatigue testing procedure utilizes the Gleeble™ thermo-mechanical simulator and was developed to closely match extreme service conditions. Test samples with notched gauge section were subjected to repeating thermal cycles under fixed displacement to restrict the sample expansion and contraction, during heating and cooling, and simulate high level of structural restraint. The temperature range of thermal cycling was between 1110°F (600°C) and 2040°F (1115°C) with heating rate of 10,000°F/hr (1.54°C/s) and cooling rate of 83,462°F/hr (12.88°C/s). The following parameters were recorded and used for ranking the thermal fatigue cracking susceptibility: number of cycles to failure, stress vs. time integral, maximum experienced tensile and compressive stresses, and change in gauge section area. All failed test samples were subjected to fracture surface analysis using scanning electron microscopy. The non-failed samples were examined for notch cracks using binocular microscope at up to x100 magnification. The gauge section of all tested samples was characterized with light optical and scanning electron microscopy to correlate crack nucleation and propagation to susceptible microstructural constituents.
APA, Harvard, Vancouver, ISO, and other styles
2

Smith, Francis R., Glenn W. Harshberger, and Vaclav G. Ujcik. "AFTI/F-111 Performance Flight Test Summary." In Aerospace Technology Conference and Exposition. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 1987. http://dx.doi.org/10.4271/871881.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

SHAW, LEONARD, RODNEY CLARK, and DICK TALMADGE. "F-111 generic weapons bay acoustic environment." In 25th AIAA Aerospace Sciences Meeting. Reston, Virigina: American Institute of Aeronautics and Astronautics, 1987. http://dx.doi.org/10.2514/6.1987-168.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Stuckey, R. "Flight-estimated spoiler aerodynamics of the F-111C aircraft." In 19th Atmospheric Flight Mechanics Conference. Reston, Virigina: American Institute of Aeronautics and Astronautics, 1994. http://dx.doi.org/10.2514/6.1994-3459.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Sutherland, Bill. "F-111 service experience - Use of high strength steel." In 36th Structures, Structural Dynamics and Materials Conference. Reston, Virigina: American Institute of Aeronautics and Astronautics, 1995. http://dx.doi.org/10.2514/6.1995-1515.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

BONNEMA, KENNETH, and STEPHEN SMITH. "AFTI/F-111 Mission Adaptive Wing flight research program." In 4th Flight Test Conference. Reston, Virigina: American Institute of Aeronautics and Astronautics, 1988. http://dx.doi.org/10.2514/6.1988-2118.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Li, Zhong, Yuan Fu, Jianyu Zhang, Liancheng Lin, Jianping Huang, Wenyu Mao, Dongsheng Yang, Dandan Zhao, and Xiao Wang. "Design and Test for a High-Temperature Molten Salt Pump." In ASME/NRC 2014 12th Valves, Pumps, and Inservice Testing Symposium. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/nrc2014-5024.

Full text
Abstract:
A high-temperature molten salt pump, described as mechanical, free-surface, centrifugal, vertical-shaft, sump type, working at 500°C [932°F] to 600°C [1112°F], has been developed for the Thorium-Based Molten Salt Reactor (TMSR). Flow passage components of the pump are made of Hastelloy C-276 to ensure sufficient strength and corrosion resistance at high temperature. Also, a heat shield plug with air-cooled channels was designed to separate the drive motor, seal elements, and bearings from intense radioactivity and to keep the temperature of the flange seal below 150°C [302°F] and the temperature of the bearing below 80°C [176°F]. A dry gas seal was used so that there is zero leakage. Furthermore, some analysis of hydraulics characteristics, temperature field, thermal stress, and strain was performed to research the pump’s performance, and then the temperature field and the hydraulics were measured to validate the analysis results. The results show that the hydraulics, thermal stress, and strain meet the design value very well. The pump has been successfully operated on a LiF-NaF-KF test loop for over 250 hr. at temperatures of 500°C [932°F] to 600°C [1112°F], speeds of 1050 to 1450rpm, and flows of 15 m3/h [66 gpm] to 25 m3/h [110 gpm]. Paper published with permission.
APA, Harvard, Vancouver, ISO, and other styles
8

Cheruvu, N. S., V. P. Swaminathan, and C. D. Kinney. "Recovery of Microstructure and Mechanical Properties of Service Run GTD-111 DS Buckets." In ASME 1999 International Gas Turbine and Aeroengine Congress and Exhibition. American Society of Mechanical Engineers, 1999. http://dx.doi.org/10.1115/99-gt-425.

Full text
Abstract:
Degradation of microstructure and mechanical properties of a service run GTD-111 DS blade was evaluated. The blade was coated with a CoCrAlY coating (GT-29) and had operated on a GE Model MS 5002 engine for 54,850 hours. To recover the microstructure of the degraded blade, the effect of solution treatment temperature on the microstructure and properties was evaluated. The blanks removed from the airfoil tip section were given a commonly used partial solution treatment 2050°F (1120°C) for GTD-111 and a high temperature solution treatment 2175°F (1190°C) prior to the partial solution and aging treatments. Microstructure and creep test results of these heat treated specimens revealed that the high temperature solution treatment was necessary to recover the microstructure and properties of in-service degraded GTD-111 DS buckets.
APA, Harvard, Vancouver, ISO, and other styles
9

Grove, James, Leonard Shaw, John Leugers, and Graham Akroyd. "USAF/RAAF F-111 Flight Test with Active Separation Control." In 41st Aerospace Sciences Meeting and Exhibit. Reston, Virigina: American Institute of Aeronautics and Astronautics, 2003. http://dx.doi.org/10.2514/6.2003-9.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Kimura, Kazuhiro, and Kota Sawada. "Creep Deformation Property and Creep Life Evaluation of Super304H." In ASME 2020 Pressure Vessels & Piping Conference. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/pvp2020-21623.

Full text
Abstract:
Abstract Creep deformation behavior, creep strength property and microstructural evolution during creep exposure were investigated on Super 304H steel for boiler tube. In the high stress and lower temperature regime, creep rupture strength of Super 304H steel is higher than that of SUS304H steel. The slope of stress vs. time to rupture curve of Super 304H steel, however, becomes steeper with increases in creep exposure time and temperature, and the creep rupture strength of Super 304H steel becomes closer to that of SUS304H steel after the tens of thousands of hours at 700°C (1292°F) and above. In the short-term, at 600°C (1112°F), creep rupture ductility increases with increase in creep rupture life. However, it tends to decrease after showing this maximum value and the creep rupture ductility decreases with increase in temperature. The complex shape of creep rate vs. time curves, with two minima in creep rate, was observed at 600°C (1112°F). Several type precipitates of niobium carbonitride (Nb(C,N)), Z phase (NbCrN), and copper were observed in Super 304H steel, as well as M23C6 carbide and sigma phase observed in SUS304H steel. The change in slope of stress vs. time to rupture curve is caused by disappearance of precipitation strengthening effect during creep exposure. Accuracy of creep rupture life evaluation was improved by stress range splitting method which takes into account the change in slope of stress vs. time to rupture curves was demonstrated.
APA, Harvard, Vancouver, ISO, and other styles

Reports on the topic "F-111s"

1

Sotello, Wendy J., III Penner, Scharf John T., and Cynthia K. F/FB-111 Avionics Test Station and Component Specialist/Technician (AFSC 451X6) Training Requirements Analysis. Fort Belvoir, VA: Defense Technical Information Center, November 1991. http://dx.doi.org/10.21236/ada252048.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Bowman, Daniel R. Coupon and Birdstrike Testing of F-111 ADBIRT Windshields Which Have Been Subjected to Simulated Pressure/Thermal Service Life. Fort Belvoir, VA: Defense Technical Information Center, January 1992. http://dx.doi.org/10.21236/ada251767.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Raymond, Kara, Laura Palacios, and Evan Gwilliam. Status of climate and water resources at Big Bend National Park: Water year 2019. Edited by Tani Hubbard. National Park Service, September 2022. http://dx.doi.org/10.36967/2294267.

Full text
Abstract:
Climate and hydrology are major drivers of ecosystem structure and function, particularly in arid and semi-arid ecosystems. Understanding changes in climate, groundwater, streamflow, and water quality is central to assessing the condition of park resources. This report combines data collected on climate, groundwater, and springs at Big Bend National Park (NP) to provide an integrated look at climate and water conditions during water year (WY) 2019 (October 2018–September 2019). However, this report does not address the Rio Grande or its tributaries. Annual precipitation was higher than normal (1981–2010) for Big Bend NP at four of the five National Oceanic and Atmospheric Administration Cooperative Observer Program weather stations: 111% of normal for Chisos Basin, 122% of normal for Panther Junction, 155% of normal for Persimmon Gap, and 124% of normal for Rio Grande Village. Castolon had 88% of normal annual precipitation. All five stations had higher than normal rainfall in October and December, while rainfall totals were substantially below normal at all stations in November, February, and March. Monthly precipitation totals for April through September were more variable from station to station. Mean monthly maximum air temperatures were below normal in the fall months, with Panther Junction as much as 7.5°F below normal in October. Monthly temperatures from January through July were more variable. Temperatures in August and September were warmer than normal at every station, up to +9.4°F at Rio Grande Village and +8.7°F at Chisos Basin in July. The reconnaissance drought index values indicate generally wetter conditions (based on precipitation and evaporative demand) at Chisos Basin since WY2016 and at Panther Junction and Persimmon Gap since WY2015, except for WY2017. This report presents the manual and automatic groundwater monitoring results at nine wells. Five wells had their highest water level in or just before WY2019: Panther Junction #10 peaked at 99.94 ft below ground surface (bgs) in September 2018, Contractor’s Well peaked at 31.43 ft bgs in November 2018, T-3 peaked at 65.39 ft bgs in December 2018, K-Bar #6 Observation Well peaked at 77.78 ft bgs in February 2019, and K-Bar #7 Observation Well peaked at 43.18 ft bgs in February 2019. This was likely in response to above normal rainfall in the later summer and fall 2018. The other monitoring wells did not directly track within-season precipitation. The last measurement at Gallery Well in WY2019 was 18.60 ft bgs. Gallery Well is located 120 feet from the river and closely tracked the Rio Grande stage, generally increasing in late summer or early fall following higher flow events. Water levels in Gambusia Well were consistently very shallow, though the manual well measurement collected in April was 4.25 ft bgs—relatively high for the monitoring record—and occurred outside the normal peak period of later summer and early fall. The last manual measurement taken at TH-10 in WY2019 was 34.80 ft bgs, only 0.45 ft higher than the earliest measurement in 1967, consistent with the lack of directional change in groundwater at this location, and apparently decoupled from within-season precipitation patterns. The last water level reading in WY2019 at Oak Springs #1 was 59.91 ft bgs, indicating an overall decrease of 26.08 ft since the well was dug in 1989. The Southwest Network Collaboration (SWNC) collects data on sentinel springs annually in the late winter and early spring following the network springs monitoring protocol. In WY2019, 18 sentinel site springs were visited at Big Bend NP (February 21, 2019–March 09, 2019). Most springs had relatively few indications of natural and anthropogenic disturbances. Natural disturbances included recent flooding, drying, and wildlife use. Anthropogenic disturbances included flow modifications (e.g., springboxes), hiking trails, and contemporary human use. Crews observed one to seven facultative/obligate wetland plant...
APA, Harvard, Vancouver, ISO, and other styles
4

Dickman, Martin B., and Oded Yarden. Genetic and chemical intervention in ROS signaling pathways affecting development and pathogenicity of Sclerotinia sclerotiorum. United States Department of Agriculture, July 2015. http://dx.doi.org/10.32747/2015.7699866.bard.

Full text
Abstract:
Abstract: The long-term goals of our research are to understand the regulation of sclerotial development and pathogenicity in S. sclerotior11111. The focus in this project was on the elucidation of the signaling events and environmental cues involved in the regulation of these processes, utilizing and continuously developing tools our research groups have established and/or adapted for analysis of S. sclerotiorum, Our stated objectives: To take advantage of the recent conceptual (ROS/PPs signaling) and technical (amenability of S. sclerotiorumto manipulations coupled with chemical genomics and next generation sequencing) developments to address and extend our fundamental and potentially applicable knowledge of the following questions concerning the involvement of REDOX signaling and protein dephosphorylation in the regulation of hyphal/sclerotial development and pathogenicity of S. sclerotiorum: (i) How do defects in genes involved in ROS signaling affect S. sclerotiorumdevelopment and pathogenicity? (ii) In what manner do phosphotyrosinephosphatases affect S. sclerotiorumdevelopment and pathogenicity and how are they linked with ROS and other signaling pathways? And (iii) What is the nature of activity of newly identified compounds that affect S. sclerotiori,111 growth? What are the fungal targets and do they interfere with ROS signaling? We have met a significant portion of the specific goals set in our research project. Much of our work has been published. Briefly. we can summarize that: (a) Silencing of SsNox1(NADPHoxidase) expression indicated a central role for this enzyme in both virulence and pathogenic development, while inactivation of the SsNox2 gene resulted in limited sclerotial development, but the organism remained fully pathogenic. (b) A catalase gene (Scatl), whose expression was highly induced during host infection is involved in hyphal growth, branching, sclerotia formation and infection. (c) Protein tyrosine phosphatase l (ptpl) is required for sclerotial development and is involved in fungal infection. (d) Deletion of a superoxidedismutase gene (Sssodl) significantly reduced in virulence on both tomato and tobacco plants yet pathogenicity was mostly restored following supplementation with oxalate. (e) We have participated in comparative genome sequence analysis of S. sclerotiorumand B. cinerea. (f) S. sclerotiorumexhibits a potential switch between biotrophic and necrotrophic lifestyles (g) During plant­ microbe interactions cell death can occur in both resistant and susceptible events. Non­ pathogenic fungal mutants S. sclerotior111n also cause a cell death but with opposing results. We investigated PCD in more detail and showed that, although PCD occurs in both circumstances they exhibit distinctly different features. The mutants trigger a restricted cell death phenotype in the host that unexpectedly exhibits markers associated with the plant hypersensitive (resistant) response. Using electron and fluorescence microscopy, chemical effectors and reverse genetics, we have established that this restricted cell death is autophagic. Inhibition of autophagy rescued the non-pathogenic mutant phenotype. These findings indicate that autophagy is a defense response in this interaction Thus the control of cell death, dictated by the plant (autophagy) סr the fungus (apoptosis), is decisive to the outcome of certain plant­ microbe interactions. In addition to the time and efforts invested towards reaching the specific goals mentioned, both Pls have initiated utilizing (as stated as an objective in our proposal) state of the art RNA-seq tools in order to harness this technology for the study of S. sclerotiorum. The Pls have met twice (in Israel and in the US), in order to discuss .נחd coordinate the research efforts. This included a working visit at the US Pls laboratory for performing RNA-seq experiments and data analysis as well as working on a joint publication (now published). The work we have performed expands our understanding of the fundamental biology (developmental and pathogenic) of S. sclerotioז111וז. Furthermore, based on our results we have now reached the conclusion that this fungus is not a bona fide necrotroph, but can also display a biotrophic lifestyle at the early phases of infection. The data obtained can eventually serve .נ basis of rational intervention with the disease cycle of this pathogen.
APA, Harvard, Vancouver, ISO, and other styles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography