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Biancalana, Adriano. "Analise morfologica, biomecanica e bioquimica de tendão de ratos Zucker (fa/fa) obesos." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317667.
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Orientadores: Laurecir Gomes, Licio Augusto VellosoTese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia
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Resumo: A obesidade é considerada hoje uma epidemia mundial. A obesidade é um dos maiores problemas de saúde pública em muitas partes do planeta, onde cresce em taxas alarmantes. No Brasil, a diminuição das taxas de desnutrição vieram acompanhadas pelo aumento das taxas de sobrepeso e obesidade. A obesidade pode ser definida como o acúmulo anormal ou excessivo de gordura, que pode prejudicar a saúde. A obesidade aumenta significativamente o risco do desenvolvimento de problemas de saúde como a hipertensão arterial, derrame, problemas respiratórios, diabetes Melitus (Tipo II), incidência de certas formas de câncer, doenças do coração, alterações músculo esqueléticas e osteoartrites das grandes e pequenas articulações. Sendo que a adiposidade está relacionada aos níveis individuais de gordura para cada individuo. A função dos tendões é transmitir a força criada nos músculos aos ossos, possibilitando o movimento articular. Os tendões são constituídos por células (tenócitos e tenoblastos) e por uma matriz extracelular desenvolvida, constituída por macromoléculas que interagem entre si e com a célula que a produz. A matriz extracelular dos tendões é constituída por colágeno, proteoglicanos e proteínas não colagênicas. Este trabalho objetivou analisar as alterações morfológicas, bioquímicas e biomecânicas do tendão do músculo flexor digital profundo em ratos Zucker geneticamente obesos (fa/fa) e dos animais magros (Fa/_). Os ratos Zucker possuem receptores para leptina não funcionais, e devido a isso desenvolvem obesidade. A avaliação histológica não revelou diferenças, assim como os testes imunohistoquímicos para colágeno do tipo III, nos tendões de ambos os grupos. Na análise ultraestutural do tendão de ambos os animais foram observadas gotículas de lipídio ao longo dos feixes de fibrilas de colágeno. Somente os animais obesos apresentaram fibrilas de colágeno desorganizadas, diferente da distribuição típica esperada para o tecido. O diâmetro das fibrilas de colágeno apresentou distribuição e diâmetro de massa-médio diferente entre os dois grupos. Com relação aos parâmetros mecânicos houve diferença significativa com relação ao deslocamento e a deformação máxima. Os animais obesos apresentaram conteúdo maior de hidroxiprolina enquanto os animais magros apresentaram maior quantidade de proteínas não colagênica e de glicosaminoglicanos. Devido ao elevado sobrepeso e as características do tendão dos animais obesos pode ser concluído que a influência da obesidade sobre os tendões provoca alterações na constituição e organização dos componentes da matriz extracelular. Alterações estas que podem ser relacionadas a modificações organizacionais e estruturais dos feixes de colágeno, influenciando as propriedades mecânicas do tendão e a evolução para um estado patológico.
Abstract: Obesity is considered a worldwide epidemic, one of the biggest public health problems in many parts of the planet, which grows in alarming rates. In Brazil, the decline in rates of malnutrition has been accompanied by rising rates of overweight and obesity, which can be defined as the accumulation of abnormal or excessive fat which presents a risk to health. Obesity significantly increases the risk of developing health problems as hypertension, stroke, respiratory problems, diabetes, cancer, cardiovascular diseases, skeletal muscle alteration and osteoarthritis. The tendons transmit the strength created in muscles to bones, allowing the joints movement. Tendons consist of cells (tenocyte and tenoblast) and an abundant extracellular matrix composed by collagen, proteoglycans and non-collagenous proteins. This study aimed to analyze the morphological, biochemical and biomechanical alterations of the deep digital flexor tendon in Zucker rats genetically obese (fa/fa) and of lean animals (Fa/_). Histological evaluation and immunohistochemical tests for collagen type III, showed no differences in tendons of both groups. Ultrastructural analysis, showed presence of lipid droplets on the bundles collagen. Only the obese animals showed disorganization in the distribution of fibrils. The diameter of collagen fibrils presented different distribution and mass-average diameter between the two groups, being bimodal in lean rats and unimodal in obese rats. With regard to mechanical parameters significant difference was observed, larger maximum displacement and strain in obese animals. The obese animals presented higher content of hydroxyproline while lean animals showed a larger amount of non-collagenous proteins and glycosaminoglycans. Due to the high overweight of the obese animals can be concluded that the obesity causes changes in the composition and organization of extracellular matrix of the tendon. These alterations may be related to organizational and structural changes of collagen bundles, influencing the mechanical properties of tendon and developments toward a pathological condition.
Doutorado
Biologia Celular
Doutor em Biologia Celular e Estrutural
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Slyvka, Y., Y. Feldman, S. R. Inman, and F. V. Nowak. "Kidney nos isoforms variance in female zucker rats (FA/FA) on antioxidant diet." Thesis, Видавництво СумДУ, 2008. http://essuir.sumdu.edu.ua/handle/123456789/11454.
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TharinduPriyanDeAlwis, MahappuKankanamge. "PCA and FA model for Matrix Valued Time Series Data." OpenSIUC, 2017. https://opensiuc.lib.siu.edu/theses/2197.
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Due to the advance of storage technology in computers, matrix valued time series observations are collecting in many fields like finance, economics, weather forecasting, and many fields. The matrix valued data bring information along its row wise and column wise, and if they are collect over the time we have to treat the data as a time series. If we use classical dimension reduction by converting the matrix into a long vector, the structural information is lost. Here, we discuss two different ways of dimension reduction namely: PCA model for matrix valued time series data and the FA model for matrix valued time series data which keep the matrix structure and reduce the dimension of the observed data. The estimating procedure, theoretical properties and a simulation study are presented and demonstrated for both of these models.
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Langley, Simon Cooke. "Central activity of glucocorticoids and glucocorticoid receptors in the genetically obese zucker rat (fa/fa)." Thesis, University of Southampton, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.293839.
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Nakouzi, Ghunwa Akram. "Genetic and Phenotypic Response of Neural Tube Defect Mouse Mutants to Folic Acid." Case Western Reserve University School of Graduate Studies / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=case1246538783.
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Allars, J. M. "Regulation of diet induced brown adipose tissue thermogenesis in the genetically obese (fa/fa) Zucker rat." Thesis, University of Southampton, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.377433.
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Stoller, Dora. "FA Fièvre aphteuse chez les bovins." [S.l.] : [s.n.], 2001. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.
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Cole, Rachel M. "The effects of fermented soy and soy diets on hepatic lipid composition in zucker (fa/fa) rats." Connect to resource, 2006. http://hdl.handle.net/1811/6601.
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Thesis (Honors)--Ohio State University, 2006.Title from first page of PDF file. Document formatted into pages: contains 26 p.; also includes graphics. Includes bibliographical references (p. 23-26). Available online via Ohio State University's Knowledge Bank.
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D'Isep, Marta <1988>. "«L’uomo fa il luogo e il luogo fa l’uomo». Il paesaggio-personaggio ne "Le Confessioni d'un italiano"." Master's Degree Thesis, Università Ca' Foscari Venezia, 2013. http://hdl.handle.net/10579/2926.
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Marchington, D. R. "Regulation of brown adipose tissue by the sympathetic nervous system in the genetically obese (fa/fa) Zucker rat." Thesis, University of Southampton, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356785.
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MARIE-MOHAMMAD-ALI, MARIE VERONIQUE. "Role du systeme nerveux sympathique et des hormones thyroidiennes dans l'installation de l'obesite du rat zucker fa/fa." Paris 7, 1994. http://www.theses.fr/1994PA077066.
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Nous avons voulu preciser le role du systeme nerveux sympathique et des hormones thyroidiennes dans l'installation de l'obesite du rat zucker fafa en etudiant: la capacite de conversion de la thyroxine en triiodothyronine, l'hormone active, dans differents tissus et l'effet de l'administration aigue d'un agoniste beta-adrenergique atypique sur l'activite du tissu adipeux. Chez le rat preobese nouveau-ne compare a son frere non obese, on detecte une reduction de la capacite de production de triiodothyronine dans le tissu adipeux brun. Cette difference disparait a la fin de la periode d'allaitement. Dans le foie, au contraire, l'activite desiodase, est normale, puis elle diminue apres le sevrage, de sorte qu'une faible capacite de production de triiodothyronine est maintenue chez l'obese. La concentration serique de cette hormone est effectivement diminuee des la deuxieme semaine de la vie ; ce defaut pourrait affecter la production d'energie dans les autres tissus, notamment le muscle. Dans le cerveau, la capacite de conversion de la thyroxine en triiodothyronine est normale, puis augmentee au moment du sevrage, lorsque la concentration serique en thyroxine libre diminue significativement, permettant ainsi de preserver la concentration locale en hormone active. L'administration d'agoniste beta-adrenergique corrige la plupart des alterations du tissu adipeux brun. L'ensemble de nos resultats suggere qu'une diminution de la stimulation sympathique intervient tres tot dans l'installation de l'obesite du rat zucker, et confirme que le tissu adipeux brun est un site precoce de l'expression du gene fa
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HALLAKOU, SOPHIE. "Thiazolidinediones et sensibilite a l'insuline : actions au niveau adipocytaire et musculaire chez le rat zucker obese fa/fa." Paris 7, 1998. http://www.theses.fr/1998PA077075.
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Le diabete noninsulinodependant se caracterise par une alteration de la secretion d'insuline et par une insulinoresistance. Une famille d'antidiabetiques oraux, les thiazolidinediones (tzd), dont l'action passe par une amelioration de la sensibilite a l'insuline est commercialisee. Le mecanisme d'action des tzd est aujourd'hui tres mal connu. Les tzd sont des ligands d'un recepteur nucleaire adipocytaire : le ppar. Celui-ci est implique dans le processus de differenciation adipocytaire. Il a ete etabli une relation directe entre l'activite antidiabetique des tzd et leur affinite pour le ppar. Le but de notre travail a ete d'etudier chez le rat obese zucker fa/fa quelle etait l'action des tzd au niveau musculaire et adipocytaire. Nous avons pu verifier sur ce modele, que le traitement par la pioglitazone (pio) entraine une amelioration de la tolerance au glucose et de la sensibilite a l'insuline. Cette amelioration de la sensibilite a l'insuline affecte le tissu adipeux et les muscles. Dans le tissu adipeux blanc, la pio entraine une augmentation de l'expression de proteines controlant les etapes clefs de l'utilisation de glucose : le transporteur de glucose glut4, la synthase des acides gras et enfin la phosphoenolpyruvate carboxykinase (pepck). L'augmentation de l'expression de ces genes pouvait s'expliquer soit par une action genique directe de la pio soit par une augmentation de la differenciation adipocytaire. Un traitement court par la pio entraine une augmentation de l'expression de genes identifies comme etant des marqueurs precoces du processus de differenciation adipocytaire : c/ebp et a2co16. Le denombrement des adipocytes revele que la pio entraine une augmentation du nombre de petits adipocytes. Ces deux observations demontrent que la pio in vivo active la differenciation adipocytaire. Les petits adipocytes sont capables de se charger en triglycerides a la suite d'un regime riche en lipides. La pio exerce egalement un effet direct sur l'expression de la pepck dans des adipocytes matures primaires en culture. Enfin, nous avons montre que l'augmentation de la sensibilite a l'insuline musculaire par la pio, in vivo, n'est pas due a une augmentation de la differenciation adipocytaire intramusculaire ni a une dedifferenciation des myoblastes en adipoblastes comme ceci a ete suggere in vitro.
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NAGATA, KOHZO, TOYOAKI MUROHARA, SHOGO WATANABE, YUURI TAKESHITA, SAE OHURA, TAMAYO MURASE, TAKUYA HATTORI, MIWA TAKATSU, and KEIJI TAKAHASHI. "Premature Cardiac Senescence in DahlS.Z-Lepr fa/Lepr fa Rats as a New Animal Model of Metabolic Syndrome." Nagoya University School of Medicine, 2014. http://hdl.handle.net/2237/19482.
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Paramasivam, Jithendra. "Awning Arm Folding Mechanism : FA-40 Series." Thesis, Högskolan i Halmstad, Maskinteknisk produktframtagning (MTEK), 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-31074.
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The necessity to change the mechanism of the arm folding is to make a major difference in the field of Sun roofing systems and also to reduce the cost of the Awning system. The reduction of cost may help the market of the awning system to reach the Upper- Middle Class customers. In this project various technical solutions were investigated by simulation softwares and the data was taken into consideration. The best solution has been processed and investigated in depth with cost and material cost with high preference which cannot be exceeded when compared to today’s Awning arm folding solution. The best solution for replacing today’s mechanism is a torsion spring folding mechanism. The torsion spring has been designed and simulated using the SolidWorks simulation software. A virtual bench test of the Awning system has been created and designed using SolidWorks and the working mechanism has been tested virtually. The torsion spring’s data was calculated by using a spring dimension calculator. The spring data has been included in the bench test and the test simulation has been run by a virtual technique and then the result has been obtained by the virtual test bench. The torsion spring’s stress and strain analysis during maximum load on the Awning in an open condition has also been calculated for the study purpose of the spring stability and compared with the previous method of the awning system in order to calculate the factor of safety (FOS) equal or more stabilise for the environment as it has been used. The environmental condition is a main focus in this project. There are different types of weather conditions in Sweden. Customers may use the Awning during rainy weather. While it is raining the rain water are collected on top of the fabric. In order to withstand the weight of the water the arm of the awning should be strong. Hence the environmental condition is a main factor in this project with respective to speed of the wind. The economical manufacturing cost for the product and the replacement of the arm folding mechanism are mainly focused.
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Tzeng, Chin-Fa. "Mes de la fotografía: Tzeng - Chin Fa." Universidad Peruana de Ciencias Aplicadas (UPC), 2021. http://hdl.handle.net/10757/657590.
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El Mes de la fotografía compartirá en esta edición las obras de cinco reconocidos fotógrafos de Taiwán que serán expuestas en el emblemático pasaje Santa Rosa a pocos metros de la Plaza Mayor de Lima. La carrera de Comunicación y Fotografía de la Universidad Peruana de Ciencias Aplicadas (UPC) con el apoyo de la Oficina Económica y Cultural de Taipéi en Lima y el Programa Spotlight Taiwán del Ministerio de Cultura de Taiwán compartirán a la sociedad peruana el trabajo fotográfico de Annie Hsiao-Ching Wang, Yehlin Lee, Shen Chao-Liang, Ze Wei y Tzen Chin-Fa.
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Treffandier, Hélène. "Etude du phosphorelais RcsCDB/FA d'Escherichia coli." Toulouse 3, 2009. http://thesesups.ups-tlse.fr/797/.
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Les phosphorelais histidine-aspartate constituent la voie préférentielle de transduction des signaux environnementaux chez les bactéries et médient un grand nombre de réponses adaptatives différentes. Le système Rcs d'Escherichia coli est un phosphorelais complexe constitué de cinq protéines RcsCDBFA. Exclusif des Entérobactéries, il module la formation des biofilms et la virulence de différents pathogènes. Il est activé par des altérations de l'enveloppe et contrôle 2 à 3 % du génome bactérien. Cependant, le rôle du système Rcs dans l'adaptation des cellules à leur environnement reste peu documenté. Mon travail de thèse avait pour objectifs (i) de progresser dans la connaissance du rôle du système Rcs dans des conditions environnementales pertinentes (ii) de rationaliser la complexité du phosphorelais Rcs et notamment d'expliquer le rôle du co-facteur accessoire RcsA au sein de la réponse Rcs (iii) de tendre vers une vision intégrative du système par l'identification de ses partenaires protéiques. Dans le cadre de ces objectifs, mon travail de thèse a démontré le rôle essentiel du système Rcs pour la survie aux pHs acides, situation rencontrée par l'entérobactérie E. Coli dans l'estomac des mammifères. Mes travaux suggèrent également que le co-facteur accessoire RcsA affecte la cinétique d'expression de l'ensemble des gènes du régulon RcsB et qu'il permet notamment de prolonger la réponse Rcs après la disparition du signal activateur du phosphorelais. Pour finir, il apparaît que la régulation de rcsA est bien plus complexe qu'initialement supposée. En effet, mes résultats ont mis en évidence deux niveaux de régulation : transcriptionnel et post-transcriptionnelTwo-component systems, also called phosphorelays are the major signalling pathways in bacteria. They are widespread and mediate a large variety of adaptative cellular responses. The Rcs system of Escherichia coli is a complex phosphorelay composed of five proteins: RcsCDBFA. Exclusive to the Enterobacteriacae, the Rcs phosphorelay modulates biofilm formation and virulence in several pathogens. It is activated by membrane alterations and influences expression of 2 to 3% of the bacterial genome. However, the role of the Rcs system in adaptation to the environment remains elusive. The three objectives of my PhD were (i) to explore further the role of the Rcs system in adaptation to relevant environmental conditions (ii) to rationalize the complexity of the Rcs phosphorelay and, in particular, to explain the role of the accessory co-factor RcsA in the Rcs response (iii) to develop an integrated vision of the system through the identification of its protein partners. Within the framework of these objectives, my work proved that the Rcs system is essential for resistance to low pH, a situation encountered by E. Coli in mammals' stomach. My research also suggests that the accessory cofactor RcsA modulates the kinetics of expression of the whole RcsB regulon, in particular by prolonging the Rcs response after the phosphorelay's activating signal has stopped. To finish with, my work revealed a greater complexity in rcsA regulation than was previously thought to exist, by showing that it is twofold: transcriptional and post-transcriptional
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Hori, Tsuyoshi. "Qin Han fa zhi shi lun kao." [Peking] : Fa lü chu ban she : Xin hua shu dian jing xiao, 1988. http://books.google.com/books?id=Hz06AAAAMAAJ.
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Zhu, Yong. "Qing dai zong zu fa yan jiu." Changsha Shi : Hunan jiao yu chu ban she : Hunan Sheng xin hua shu dian jing xiao, 1987. http://books.google.com/books?id=-tbSAAAAMAAJ.
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CHARON, CHRISTINE. "Mecanismes impliques dans le defaut d'activation sympathique du tissu adipeux brun du jeune rat zucker (fa/fa) pre-obese." Paris 6, 1995. http://www.theses.fr/1995PA066561.
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Le rat zucker fa/fa genetiquement obese se caracterise tres precocement par une augmentation du stockage d'energie dans les tissus adipeux associee a une diminution de la depense energetique. Bien que localise, le gene fa n'a pas encore ete clone et sa fonction reste inconnue. Dans l'hypothese ou un defaut d'activite sympathique pourrait jouer un role dans l'installation de cette obesite, nous avons cherche a savoir si l'administration d'agonistes -adrenergiques, durant la phase d'installation de la pathogenie, est capable de corriger outre le defaut de thermogenese, les autres anomalies qui caracterisent le tissu adipeux brun (tab) du jeune rat zucker pre-obese. Nous avons montre que l'administration chronique d'agonistes 3-adrenergiques, pendant la deuxieme semaine de la vie, limite le developpement de l'obesite et corrige la plupart des anomalies du tab du jeune rat zucker fa/fa pre-obese: (i) le contenu en lipides des tissus adipeux brun et blanc et l'hyperinsulinemie sont significativement diminues ; (ii) dans le tab, la capacite de thermogenese est restauree a un niveau comparable de celui des temoins non-obeses, l'hyperactivite de la synthetase des acides gras est diminuee, le deficit en lipoproteine lipase (activite et arn messagers) est partiellement corrige et la reduction du contenu en arn messagers du transporteur du glucose glut4 est totalement corrigee. Ainsi, un defaut d'activite sympathique pourrait jouer un role dans le developpement de cette obesite genetique. Afin de preciser le niveau de cette alteration, nous avons cherche a savoir si, dans le tab du rat pre-obese fa/fa age de 14 jours, la transduction du message catecholaminergique est alteree. Une approche pharmacologique et moleculaire nous a permis de mettre en evidence, une diminution de l'activite basale et stimulee (par differents agonistes - en particulier 3-adrenergiques) de l'adenylate cyclase (ac) dans le tab du rat zucker fa/fa pre-obese sans que l'activite de la sous-unite catalytique de l'ac soit affectee. Cette diminution d'activation par les catecholamines s'explique: (i) par la diminution de l'activite de la sous-unite stimulatrice de la proteine g (alphags) sans modification de celle de la sous-unite inhibitrice (alphagi) mais neanmoins, sans variation de la quantite de ces proteines dans la membrane plasmique ; (ii) par des differences, entre les deux genotypes, d'efficacite de couplage des recepteurs 1 et 3-adrenergiques a l'ac. En effet, malgre une diminution significative de la concentration des arn messagers du recepteur 3 chez le pre-obese compare au non-obese, aucune difference qualitative et quantitative de ces recepteurs n'a pu etre mise en evidence entre les deux genotypes. Ainsi, le rat zucker fa/fa pre-obese se caracterise tres precocement par une alteration de la transduction du message catecholaminergique au niveau du tab et par un defaut d'activite sympathique. Ces resultats sont en accord avec l'hypothese de l'existence d'un defaut central, chez le rat zucker fa/fa, pouvant contribuer a l'installation de son obesite. Des etudes recentes viennent de mettre en evidence que la mutation fa pourrait affecter un recepteur (non encore identifie) au niveau hypothalamique implique dans la reception d'un signal hormonal d'origine adipocytaire (leptine) permettant de reguler la masse adipeuse par des mecanismes non encore determines
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Kibenge, Molly J. Twinomwe. "Interaction between high-fat diet, adrenalectomy and/or exercise on pancreatic B-cell function in obese Zucker (fa/fa) rats." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/Nq48804.pdf.
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Sun, Zhiyang. ""Zuo zhuan" zhong de "shi dong yong fa" /." View abstract or full-text, 2006. http://library.ust.hk/cgi/db/thesis.pl?HUMA%202006%20SUN.
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Brochu, Mathieu. "Joining Si₃N₄ to FA-129 iron aluminide." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=84482.
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Joints between dissimilar materials are characterized particularly by compositional gradients and microstructural changes, which yield large variations in chemical, physical and mechanical properties across the joint. The joining of dissimilar materials is therefore more complex than the joining of similar materials. In this project, the joining procedure, from the interaction between the different components in a joint to the determination of the mechanical properties was applied to the Si3N4/FA-129 system. This iron aluminide intermetallic alloy (FA-129), was developed by Oak Ridge National Laboratories (ORNL) to have high temperature properties with good room temperature ductility. This intermetallic is replacing high strength ferritic stainless steel (SS) in moderate strength applications due to cost and property reasons. Joints between SS and Si3N4 are already used industrially and this project was to evaluate the potential to replace these Si3N 4/SS joints by those of Si3N4/FA-129.Broadly stated, the results obtained during this project are as follows: (I) The E2 energy for Si3N4 ceramic was calculated to be 3.01 keV. (II) The wetting of iron aluminide alloy by copper has been achieved and the spreading and reaction kinetics are influenced by the presence of Cr as alloying element. (III) The penetration and decohesion of the FA-129 microstructure is significantly reduced by the utilization of a Cu alloy containing a high titanium concentration. (IV) An active brazing alloy containing a high active element content can be fabricated by an electroless deposition technique. (V) The melting behavior of the powder was characterized and complete melting occurs in a multi-step process at different temperatures, which are a function of the heating rate. (VI) The strength of joint produced by brazing Si3N4 to itself using the composite powder reached 400 MPa. (VII) Direct brazing of Si 3N4 to FA-129 was shown to be unsuccessful and therefore a soft Cu interlayer was inserted to absorb residual stresses. The maximum joint strength reached was 160 MPa. (VIII) Partial Transient Liquid Phase Bonding was successfully applied to the Si3N4/FA-129 system using a nickel interlayer. The conventional silicide and nitride layers were not observed as the silicide layer dissolved into the nickel core at high temperature. The strength of the assembly was measured and a strength of 80 MPa was obtained, independent of the joining parameters.
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蕭偉成 and Wai-shing Siu. "On a subjective modelling of VaR: fa Bayesianapproach." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B31225159.
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Ishara, Cinthia. "A-fa-si-a : um sujeito em cena." [s.n.], 2008. http://repositorio.unicamp.br/jspui/handle/REPOSIP/270977.
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Orientador: Maria Irma Hadler CoudryTese (doutorado) - Universidade Estadual de Campinas, Instituto de Estudos da Linguagem
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Resumo: Este trabalho apresenta o estudo de caso de um sujeito afásico (CN). Através de seu acompanhamento longitudinal, realizado com base em uma abordagem discursiva da afasia, buscou-se compreender as características de sua afasia, discutindo as classificações propostas na literatura e a relação entre sua caracterização e o processo terapêutico. Esta tese destaca as características singulares de um caso que se recusa a encaixar-se nas tipologias existentes, evidenciando a heterogeneidade do fenômeno afásico e as contribuições de um processo terapêutico que não exclui o sujeito. Os dados mostram as relações entre os níveis lingüísticos e apontam que os gestos articulatórios não caminham dissociados de outros aspectos da linguagem em seu funcionamento. O esforço para conter cadeias de associações fônicas e a constante re-instauração da cena enunciativa na produção de seus enunciados se destacam enquanto características do funcionamento da afasia de CN. O processo terapêutico mostra que não se trata de ensinar ou treinar os aspectos alterados pela afasia. O processo com CN ensina que a opção por uma teoria de linguagem que inclua o sujeito, ao invés de uma teorização voltada apenas para o sintoma e para o que falta em sua fala, se mostra decisiva para promover e explicar as mudanças que CN faz durante o período do acompanhamento
Abstract: This thesis presents a case study of an aphasic person (CN). We longitudinally examine the performance of CN in different situations. The study adopts the aphasia¿s discursive approach (Coudry, 1986/88). We try to understand changes in CN¿s language functioning and the characteristics of CN¿s aphasia. The CN¿s aphasia presentation differs from typical aphasias described in traditional typologies. CN¿s language exhibits unique characteristics that lead us to consider the heterogeneity in aphasia and the advantages of a therapeutic process based on a specific view about the relationship between language and subject. Our findings support the relationship between linguistic levels and the relation between articulatory gestures and other language aspects. The effort to limit phonic associations and to build the enunciative scene is frequent and constitutes a typical aspects that demonstrates how language works in this case. The improvements in CN¿s language functioning from our initial evaluation provides support for the language¿s view that includes the subject in its scope and the therapeutic process that is not limited to following training programs or educational treatments
Doutorado
Doutor em Linguística
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Lidbeck, Anders. "IT-system och organisationsutveckling." Thesis, Högskolan Dalarna, Informatik, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:du-5056.
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This report describes work on the thesis “IT systems and organizational development”. The work is carried out on Stocksbro Energi AB, during spring 2009. The company wanted better flow in their production but also review if the inventory management function located in Visma SPCS Administration 2000, could be used in the organization. Under the first part of this report the system were tested to ensure if the system would work together with the organization. After testing the desired features they were evaluated along with two of the users to the system at the company. The wanted functions could not be obtained whenthe Admin 2000 is an economic system and are not made for the producing companies. Thereafter the theoretical possibility was examined of introducing a more advanced system to get the desired functionality to work together with the organization. To introduce a more advanced system will require major changes of the organization, before, during and after the introduction. It is therefore important how the management implements a possibility of a new system. It’s important to make the staff join in this implementation but also get as much as possible out of the system.To conclude the thesis a goal and problem analysis but also a solution proposal was made with the help of the FA/SIMM method. Also some suggestions are mentioned how the company could proceed in the implementation of the proposals for a solution.
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Petroulakis, Kathy. "The effects of dietary zinc on adipocyte Glut 4 expression, adiposity, hyperinsulinemia and zinc status of the obese, fa/fa, Zucker rat." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0018/MQ53204.pdf.
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Py, Guillaume. "Étude du transport sarcolemmal du lactate et de l'expression des isoformes MCT1 et MCT4 chez le rat diabétique et Zucker fa/fa." Montpellier 1, 2001. http://www.theses.fr/2001MON1T014.
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Le lactate a longtemps ete considere comme un produit final de la glycolyse et le temoin d'une limitation de l'apport en oxygene au niveau des tissus. Durant les vingt dernieres annees, grace au developpement de nouvelles techniques, des travaux ont permis de montrer que le lactate etait produit en condition d'oxygenaton normale et que celui-ci etait le substrat neoglucogenique de choix au niveau hepatique. Associe aux anomalies du metabolisme du glucose, l'etat de diabete et d'insulinoresistance sont caracterises par des lactatemies basales anormalement elevees. L'origine de ces niveaux eleves de lactate est encore mal definie. Nous avons, dans ce travail, mis en evidence des alterations des echanges sarcolemmaux du lactate dans des modeles animaux de diabete et d'obesite, a l'aide d'un modele subcellulaire que sont les vesicules de sarcolemme. [. . . ] ainsi, meme si les alterations de l'activite de transport du lactate dans le diabete de type 1 ne trouvent pas leur explication dans l'expression des isoformes musculaires de mct, il semble aux vues de donnees recentes, que ceux-ci soient quand meme impliques dans la diminution de la clearance du lactate. A la difference, la perturbation musculaire des echanges et du metabolisme du lactate dans l'obesite pourrait participer a l'etat d'insulinoresistance.
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Gaučytė, Ieva. "Specialiųjų poreikių vaikų fizinis aktyvumas: pedagogų ir tėvų nuostatos." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2009~D_20140626_194858-12894.
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SANTRAUKA Tyrimo tikslas: Nustatyti tėvų ir pedagogų požiūrį į specialiųjų poreikių vaikų fizinį aktyvumą. Metodika. Šiame darbe buvo taikoma kiekybinio tyrimo metodika, anoniminės anketinės apklausos būdas. Rezultatai. Tyrimo metu buvo apklausta 120 respondentų: iš jų-70 mokytojų ir 50 tėvų. Respondentai buvo apklausti trijose Lietuvos miestuose. Tyrimo uždaviniai: 1. Išsiaiškinti tėvų – globėjų nuomonę apie specialiųjų poreikių vaikų FA. 2. Išsiaiškinti mokytojų nuomonę apie specialiųjų poreikių vaikų FA. 3. Nustatyti mokytojų ir tėvų – globėjų, nuomonę, kas turėtų padėti užsiimti FA vaikams turintiems specialiųjų poreikių. 4. Išsiaiškinti, kokios pagrindinės yra problemos trukdančios negalią turinčiam vaikui užsiimti FA Gauti tokie rezultatai: 1. Tėvų nuomone, vaikų FA yra vidutiniškai pakankamas, visiškai pakankamu jį laiko vos 6%. Tėvai – globėjai mano, kad FA ir mankšta tikrai gali padėti specialiųjų poreikių turinčiam vaikui. Tėvams svarbiausia erdvė negalią turinčiam vaikui užsiimti FA yra mokykloje per kūno kultūros pamokas. 2. Mokytojai mano, kad vaikų FA yra nepakankamas. Jie taip pat kaip tėvai svarbiausią FA erdvę išskiria mokykloje per kūno kultūros pamokas. Nors pedagogai didelę reikšmę skyrė ir namų erdvei daug labiau negu tėvai. 3. Tyrimo metu išsiaiškinome, kad abi respondentų grupės labiausiai išskiria, kad mankštos specialistai turėtų labiausiai padėti specialiųjų poreikių turintiems vaikams. Savo indelį respondentai mato mažesnį. Pedagogai labiau negu... [toliau žr. visą tekstą]Summary Aim of the research: to find out the attitudes of parents and teachers in regard to physical activity of disabled children. Methodology. Data was gathered by anonymous questionnaire and analyzed using quantitative analysis methods. Results. 120 respondents (70 teachers and 50 parents) participated in the survey. Research was conducted in thress towns (Vilnius, Kaunas and Raseiniai) in Lithuania. Tasks of the research. 1. To find out parents’ attitudes towards physical activity of disabled children. 2. To find out teachers’ attitudes towards physical activity of disabled children. 3. To find out what would be helpful for disabled children according to their parents’ and teachers’ opinions. 4. To find out why disabled children are not sufficiently physically active. The results of research. 1. In parents’ opinion, the physical activity (of children) is mainly sufficient. Only 6% of parents think that physical activity level is very high. Parents believe that physical activity and exercise can help for disable children. The best time, in their opinion, to get involved in physical activity is in school during physical education classes. 2. Teachers think that children‘s physical activity is quite poor. They think that best time to get involved in physical activity is in school during physical education classes. But teachers note that home is also an important space for children’s physical activity. 3. Both groups of respondents agreed that the best help for children could... [to full text]
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Gallala, Ramzi. "CheckBreast, l'app per la prevenzione che fa per te." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2022.
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Siu, Wai-shing. "On a subjective modelling of VaR fa Bayesian approach /." Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk/hkuto/record.jsp?B22823785.
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Hudeček, Jan. "Luciano Berio a jeho Sequenza XII pro fa got." Master's thesis, Akademie múzických umění v Praze.Hudební a taneční fakulta. Knihovna, 2015. http://www.nusl.cz/ntk/nusl-202882.
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The aim of my graduated work is the enter into problem of studies contemporary composition at the background of development music of the second half of 20th century. The work is aimed at the composition of Luciano Berio Sequenza XII. Bassoonists, who would like to study this work or studying it now, I can help them according to my practising experiences up to now and convince them how to win this "fight"
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THULARD, ADELINE. ""Ciò che fa sintomo" contributo al rinnovamento dell'analisi teatrale." Doctoral thesis, Università degli Studi di Milano, 2015. http://hdl.handle.net/2434/319746.
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“Ciò che fa sintomo…”
Contributo al rinnovamento dell’analisi teatrale
Attraverso l’analisi delle opere di Tadeusz Kantor, Pina Bausch, Jan Lauwers, Pippo Delbono ed Emma Dante, il presente studio propone un’apertura degli strumenti tradizionali degli studi teatrali ai concetti della psicanalisi e ai metodi utilizzati dai visual studies al fine di rendere conto dell’intensa esperienza emozionale suscitata dalle creazioni di questi artisti. La nozione di sintomo, teorizzata da Freud e ripresa nel campo della storia dell’arte da Georges Didi-Huberman, ci permette di superare la visione della scena come “sistema di segni” “da leggere” – sotto l’influenza della semiologia e dello strutturalismo – e di pensare al contrario ciò che nelle immagini proposte, non si lascia cogliere nell’immediato. Dopo aver mostrato i limiti degli strumenti drammaturgici, è possibile individuare i momenti in cui nelle opere studiate irrompe il gesto-sintomo, grazie all’adozione di un atteggiamento più fenomenologico. Il paradigma del sogno, in quanto modello analogico di una organizzazione-disorganizzazione, può renderci in grado di comprendere il concatenamento degli elementi scenici. Ciò che tocca lo spettatore non si situa più al livello della rappresentazione, destabilizzata dalla presenza del sintomo, ma al di sotto di quest’ultima e tra gli elementi scenici. Il rapporto al reale che si instaura per lo spettatore pertiene allora all’immaginabile piuttosto che a una forma di mimesi: le immagini aprono lo sguardo e modificano la posizione dello spettatore, colpito sia a livello corporeo che emozionale. Il soggetto teatrale diffratto, mosso dal corpo dell’attore, porta lo spettatore a fare l’esperienza dell’Altro sulla scena. Le opere in esame propongono in tal modo un’esperienza di soggetivazione e di simbolizzazione che riattiva i processi della costruzione psichica dell’individuo messa in crisi nella società contemporanea. Nel corpo a corpo che si stabilisce tra la scena e la sala, è alla propria posizione di soggetto rispetto agli altri, a se stesso e al mondo, che lo spettatore accede.“When comes the symptom…” A Contribution to the Renewal of Theatre Analysis Through an analysis of works by Tadeusz Kantor, Pina Bausch, Jan Lauwers, Pippo Delbono and Emma Dante, this thesis attempts to open up the traditional analytical tools that tend to be privileged by the discipline of theatre studies to concepts stemming from psychoanalysis or visual arts, which are more appropriate for rendering the intense emotional experience that these works induce. The notion of symptom, theorised by Freud and reappropriated by art history thanks to the work of Georges Didi-Huberman, can allow us to see the stage as more than a “system of signs”, “to be read”, under the influence of semiology and structuralism, but also to go beyond the image, towards something that is not immediately evident. Having shown the limitations of dramaturgical tools, it is possible to highlight the specific moments when a symptomatic gesture irrupts within these works by relying on a more phenomenological analysis. Dream patterns, which have the similar quality of being models of an order-disorder, are essential to our understanding of the organization of stage elements and processes. Whatever moves the spectator, is no longer strictly conditioned by representation, which is itself disrupted by the symptom, but is situated beyond it, under it, between the different scenic elements. The audience’s perception of reality becomes more reliant on imaginable rather than on some form of mimesis: images open up the gaze and alter the spectator’s stance, touching him physically and emotionally. The diffracted theatrical subject contained in the actor’s body helps the public witness Otherness onstage. The works studied here involve an experience of subjectivation and symbolisation, which activates the constitutive elements of the individual’s psyche, in crisis in contemporary society. Within the very physical relationship that is built between stage and audience, the spectator experiences his own position as a subject facing others, himself and the world.
« Ce qui fait symptôme… » Contribution au renouvellement de l’analyse du théâtre À travers l’analyse d’œuvres de Tadeusz Kantor, Pina Bausch, Jan Lauwers, Pippo Delbono et Emma Dante, cette étude propose une ouverture des outils traditionnels des études théâtrales aux concepts de la psychanalyse et aux méthodes des études visuelles pour rendre compte de l’expérience émotionnelle intense que les créations de ces artistes induisent. La notion de symptôme, théorisée par Freud et reprise dans le champ de l’histoire de l’art par Georges Didi-Huberman, permet de dépasser une vision de la scène comme « système de signes » « à lire » – sous l’influence de la sémiologie et du structuralisme – et de penser au contraire ce qui, dans les images proposées, ne se laisse pas saisir immédiatement. Après avoir montré les limites des outils dramaturgiques, il est possible de mettre en évidence les moments d’irruption du geste-symptôme dans les œuvres, en adoptant une attitude plus phénoménologique. Le paradigme du rêve, comme modèle analogique d’une organisation-désorganisation, peut nous permettre de comprendre l’agencement des éléments scéniques. Ce qui touche le spectateur ne se situe plus au niveau de la représentation, mise en branle par la présence du symptôme, mais sous celle-ci et entre les éléments. Le rapport au réel qui s’instaure pour le spectateur relève alors plus de l’imaginable que d’une forme de mimèsis : les images ouvrent le regard et modifient la position du spectateur touché corporellement et émotionnellement. Le sujet théâtral diffracté porté par le corps de l’acteur amène le spectateur à faire l’épreuve de l’Autre en scène. Les œuvres à l’étude proposent ainsi une expérience de subjectivation et de symbolisation qui réactive les processus de la construction psychique de l’individu mise en crise dans la société contemporaine. Dans le corps-à-corps qui s’installe entre la scène et la salle, c’est à sa position de sujet face aux autres, à lui-même et au monde, que le spectateur accède.
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Chen, Wenlan. "Bu qi jian pi qu tan fa zhi liao yuan fa xing gao xue ya bing de wen xian yan jiu yu tan tao /." click here to view the abstract and table of contents, 2006. http://net3.hkbu.edu.hk/~libres/cgi-bin/thesisab.pl?pdf=b19986786a.pdf.
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Artigas, Prous Josep. "L'obra poètica de Salvador Estrem i Fa. Estudi i edició." Doctoral thesis, Universitat Rovira i Virgili, 2017. http://hdl.handle.net/10803/461460.
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L'objecte d'estudi d'aquesta tesi és l'obra poètica de Salvador Estrem i Fa (Falset, 1893-1936), de la qual proposo l'estudi i l'edició filològica. Aquesta obra és constituïda per quatre volums impresos —Les hores dolces, Elegia del Priorat i altres versos, La mala collita i El Crist de la Solitud—, un mecanoscrit de cinc composicions que és l'embrió d'un recull que va romandre inacabat i un conjunt de poesies publicades en premsa que no van ser aplegades en volum. La primera part se centra en l'estudi de la figura de Salvador Estrem i de la seva poesia i compta amb tres capítols: per una banda, una aproximació biogràfica al personatge en el context de la comarca i el temps en què va viure; per altra banda, la lectura interpretativa dels quatre llibres de poesia, que ens ha permès analitzar els fonaments més rellevants d'aquesta producció poètica i la seva evolució al llarg dels anys; finalment, l'estudi detallat de la llengua que usa Estrem en les seves composicions, juntament amb els canvis que experimenta, i l'anàlisi de les formes literàries. Aquest estudi vol posar de relleu la personalitat de Salvador Estrem i la seva obra en el context de la poesia catalana del període d'entreguerres, com a representant dels autors situats al marge dels nuclis culturals predominants, i mostrar la importància del moviment cultural a la comarca del Priorat en aquest període. La segona part és l'edició filològica d'aquesta obra, precedida per tres nous capítols: la descripció dels testimonis, la història textual dels llibres publicats i de les poesies no recollides en volum i la discussió sobre els criteris d'edició. La seva finalitat és oferir les poesies de Salvador Estrem a un lector actual perquè siguin llegides sense les dificultats gràfiques i les convencions ortogràfiques d'una edició de les primeres dècades del segle XX, però tot respectant, així mateix, els valors estilístics i la llengua literària del text original. El treball conclou amb les referències de la bibliografia completa d'Estrem, tant els llibres publicats com els articles i els textos literaris apareguts en publicacions periòdiques, i de les fonts hemerogràfiques i arxivístiques que he consultat.El objeto de estudio de esta tesis es la obra poética de Salvador Estrem i Fa (Falset, 1893-1936), de la que propongo el estudio y la edición filológica. Esta obra es constituida por cuatro volúmenes impresos —Les hores dolces, Elegia del Priorat i altres versos, La mala collita y El Crist de la Solitud—, un manuscrito de cinco composiciones que es el embrión de una recopilación que permaneció inacabada y un conjunto de poesías publicadas en prensa que no fueron reunidas en volumen. La primera parte se centra en el estudio de la figura de Salvador Estrem y de su poesía, y cuenta con tres capítulos: por un lado, una aproximación biográfica al personaje en el contexto de la comarca y el tiempo en que vivió; por otra parte, la lectura interpretativa de los cuatro libros de poesía, que nos ha permitido analizar los fundamentos más relevantes de esta producción poética y su evolución; finalmente, el estudio detallado de la lengua que usa Estrem en sus composiciones, junto con los cambios que experimenta, y el análisis de las formas literarias. Este estudio quiere poner de relieve la personalidad de Salvador Estrem y su obra en el contexto de la poesía catalana del período de entreguerras, como representante de los autores situados al margen de los núcleos culturales predominantes, y mostrar la importancia del movimiento cultural en la comarca del Priorat en este periodo. La segunda parte es la edición filológica de esta obra, precedida por tres nuevos capítulos: la descripción de los testigos, la historia textual de los libros publicados y de las poesías no recogidas en volumen y la discusión sobre los criterios de edición. Su finalidad es ofrecer las poesías de Salvador Estrem a un lector actual para que sean leídas sin las dificultades gráficas y las convenciones ortográficas de una edición de las primeras décadas del siglo XX, pero respetando, asimismo, los valores estilísticos y la lengua literaria del texto original. El trabajo concluye con las referencias de la bibliografía completa de Estrem, tanto los libros publicados como los artículos y los textos literarios aparecidos en publicaciones periódicas, y de las fuentes hemerográficas y archivísticas que he consultado.
The study object of this thesis is the poetical works of Salvador Estrem i Fa (Falset, 1893-1936). I propose its study and philological edition. The poetry of Estrem consists in four printed volumes —Les hores dolces, Elegia del Priorat i altres versos, La mala collita i El Crist de la Solitud—, a typescript of five poems —a book project that remained unpublished— and a collection of poems published in newspapers which were not collected in volume. The first part deals with the study of the poetry and has three chapters: on the one hand, a short biography of the poet in the context of the region and the time in which he lived; on the other hand, the critical analysis of these four books, allowing us to analyze the most important foundations of this poetry and its evolution over the years; finally, the detailed study of the language used by Estrem in his compositions, along with the changes taking, and the analysis of literary forms found in his poems. This study seeks to highlight the personality of Salvador Estrem and his work in the context of Catalan poetry during the studied period, as a representative of the authors located outside the predominant cultural centers, and to show the importance of the cultural movement to the Priorat region in this period. The second part is the philological edition of this poetry, preceded by the description of the testimonies, the textual history of the published books and the poetry not included in volume and the discussion about the editing criteria. Its purpose is to offer the poetry of Salvador Estrem to a current reader to be read without the graphic difficulties and the spelling conventions of an old edition. The thesis concludes with the references to the complete bibliography of Salvador Estrem, both published books and articles published in journals, and an appendix with the transcription of preserved discourses and the references to the correspondence.
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Fujino, Koichi. "Social Combination| Teaching Two Fa(u)lkners and Digital Literacy." Thesis, Indiana University of Pennsylvania, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=3736801.
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This dissertation explores the ways to teach the literary works of William Clark Falkner and William Faulkner to ESL (English as a Second Language) students in today’s digital environment. William Faulkner’s great-grandfather, William Clark Falkner, wrote romantic literary works, and William Faulkner critically uses the motifs of his great-grandfather’s works to establish his literary world. Applying Bakhtin’s dialogical theory, this study explores how these two authors imagine the social formations of the American South differently in their literary works. The coined term, social combination—which is defined as the individuals’ mutual effort to have equal relationships for a certain time—is used as a key term to examine how these two authors depict the characters’ personal relationships. William Faulkner employs his characters’ social combination as a resistance against the American South’s romantic illusions that are represented by William Clark Falkner’s literary works. William Faulkner’s historical perspective is beneficial for today’s ESL students, who explore their new egalitarian formations in their digitally expanded world. The last part of this study outlines how an American literary teacher can connect the works of William Clark Falkner and William Faulkner when teaching ESL students by using today’s digital environment. Using three digital platforms—Moodle, WordPress, and Google Drive—a teacher composes egalitarian relationships among class members and inspires students’ autonomous discussion on these two authors’ works. Through these activities, ESL students are expected to comprehend that the literature of the American South is not only the historical development of the foreign region, but the phenomenon that is connected to their own social formations.
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Niittula, Anneli, and Johar Johar. "Förändringsförslag förABB:s godshantering : – Utvärdering av existerandeautomatiska datafångstmetoder." Thesis, Högskolan Dalarna, Informatik, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:du-3594.
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Examensarbetet utfördes på uppdrag av ABB i Ludvika. ABB vill öka effektiviseringen förhanteringen av inkommande gods. Detta för att det mesta sker manuellt i dagens läge och det tarmycket tid och kan resultera i felkällor.Arbetet har två syften. Det första syftet är att förändra del av verksamheten, genom att kommamed ett förändringsförslag när det gäller godshanteringen. Det andra syftet är att jämförastreckkoder och RFID för att se vilket alternativ som passar bäst.För att få fram ett förändringsförslag har vi jobbat med FA/SIM-metoden.Vi har tagit fram ett antal förändringsförslag nedan följer ett urval av dessa:• Ställa krav på leverantörerna att de skall använda streckkoder med rätt standard Code128.• Utforma tydliga och enkla kravspecifikationer för att enklare kunna ta till sig.• Förbättra nuvarande kundrelationer. Genomför en uppföljning med jämna mellanrum föratt se hur kundrelationerna sköts.
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Sůkalová, Kateřina. "Složení mastných kyselin analogů tavených sýrů." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2010. http://www.nusl.cz/ntk/nusl-216614.
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This thesis deals with the determination of fatty acids of processed cheese analogues. The aim is to identify and quantify the fatty acids in selected samples of cheese analogues. The introduction is a brief overview of the composition and properties of cheese analogues, technology and application options. The following describes the appropriate method for the determination of fatty acids in cheese and cheese analogues. Of these methods the largest part is devoted to gas chromatography, which is most frequently used method for detection of volatile fatty acids. Individual cheese analogues used for the analysis, contained various types of added fats. Specifically, the milk fat, coconut oil, sunflower oil, palm oil and butter. Samples of these fats were extracted and then converted to methylesters by methanol esterification with catalysis by potassium hydroxide. The most important fatty acids were identified and quantified in samples of cheese analogues using gas chromatography and compared with fatty acids of fats used for the preparation of these analogues are used.
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Sýkora, Michal. "Optimalizace a validace metody stanovení volných mastných kyselin." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2016. http://www.nusl.cz/ntk/nusl-240526.
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This master thesis deals with the development of method for free fatty acids determination in natural and processed cheese. In the theoretical part the possibilities of extraction, fractionation and determination of lipid fractions, characterization of fatty acids and various methods of their determination are described, as well as determination of free fatty acids. The main scope of the experimental section is optimization and validation of the selected method for determination of free fatty acids in various cheese matrices. For extraction of lipids from the sample the method with the mixture of diethylether and petrolether according to ČSN EN ISO 1735 was selected. Thin-layer chromatography and solid phase extraction were tested and compared for separation of free fatty acids. The method according to ČSN EN ISO 5509, using methanol solution of bortrifluoride, was applied for esterification. Fatty acid methyl esters were determined by gas chromatography with flame-ionization detection.
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Larsson, Eva. "FA/SIMMs tillämpbarhet vid verksamhetsdiagnos : En fallstudie om administration av kurser." Thesis, Linköping University, Department of Computer and Information Science, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-2528.
Full textAbstract:
Syftet med min undersökning är att utvärdera tillämpbarheten av metoden FA/SIMM. En utrednings- och analysansats som ska underlätta breda och välförankrade beslutsunderlag för förändringar inom olika verksamheter. Som underlag för min utvärdering har jag använt en fallstudie av grundutbildningen för informatikämnet inom ISM vid Institutionen för datavetenskap, Linköpings universitet. En fallstudie i vilken jag undersöker hur administrationen av kurser fungerar, administration i betydelsen planering, samordning och organisering av olika handlingar. I rapporten redovisar jag endast ett kort utdrag av resultatet från fallstudien. Däremot beskriver jag relativt utförligt hur det varit att arbeta praktiskt med FA/SIMM. Min upplevelse av arbetet har analyserats utifrån särskilda utvärderingskriterier som tagits fram under arbetets gång.
Resultatet av utvärderingen visar att tillämpbarheten totalt sett har stora brister för att FA/SIMM år 2003 ska kunna betraktas som praktisk att använda. Det gäller främst överskådligheten av metoden totalt. Det är inte genomskinligt vad FA/SIMM består av för delar och framför allt finns det inte någon lättillgänglig sammanställd beskrivning av alla ingående moment. Det saknas beskrivning av arbetssätt och analysstöd för vissa moment. Det finns inte heller några direkta praktiska hjälpmedel. Jag saknar också ett djupare beskrivande analysstöd som överensstämmer med metodförfattarnas perspektiv. Däremot finns det en flexibilitet att vid en verksamhetsdiagnos kunna välja vilka moment man vill använda beroende på syftet med diagnosen.
Trots ovanstående negativa kritik gick det att få fram en, i mitt tycke, relativt utförlig bild av verksamheten med en omfattande och bra översikt av bl a dess komplexitet.
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Zhao, Li Rui. "Fa (statute law), Li*(rationality), Qing(feeling) : Chinese concepts of law." Thesis, University of Macau, 2010. http://umaclib3.umac.mo/record=b2285465.
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Petravičiūtė, Monika. "Mokinių socialinės paramos, fizinės aplinkos ir mokymosi pasiekimų sąsajos su FA." Bachelor's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140620_100949-43278.
Full textAbstract:
Tyrimo objektas – Mokinių socialinės paramos, fizinės aplinkos ir mokymosi pasiekimų sąsajos su fiziniu aktyvumu
Tyrimo tikslas – Nustatyti 8–9 klasių mokinių socialinės paramos, fizinės aplinkos ir mokymosi pasiekimų sąsajas su fiziniu aktyvumu.
Uždaviniai:
1. Nustatyti mokinių fizinį aktyvumą lyties ir amžiaus aspektu.
2. Nustatyti socialinė paramos įtaką mokinių fiziniam aktyvumui.
3. Nustatyti fizinės aplinkos įtaką mokinių fiziniam aktyvumui.
4. Nustatyti mokinių mokymosi pasiekimus skirtingo fizinio aktyvumo aspektu.
5. Nustatyti fizinio aktyvumo, socialinės paramos įtakos, fizinės aplinkos ir mokinių mokymosi pasiekimų tarpusavio sąsajas.
Išvados:
1. Tyrimo metu nustatyta, kad 52,2 proc. tirtų mokinių buvo fiziškai aktyvūs ir 47,7 proc. pasyvių, fiziškai aktyvesni buvo vaikinai (p<0,05), fiziniu aktyvumu dažniau užsiima vyresni mokiniai. Dauguma mokinių fiziniam aktyvumui per savaitę skiria po 2–3 kartus per savaitę. Fiziškai aktyvesni mokiniai subjektyvų savo fizinį aktyvumą ir pajėgumą vertino aukštesniais balais.
2. Nustatyta, kad tėvai palaiko ir paremia jaunesnius mokinius ir vaikinus fiziniam aktyvumui (p<0,05). Tyrimo metu nustatyta, kad tėvai mažiau domisi vyresnio vaiko fiziniu aktyvumu, nei jaunesnio, o taip pat vaikinus fiziniam aktyvumui remia mažiau, nei merginas. Išanalizavus draugų įtaką mokinių fiziniam aktyvumui pastebėjome, kad vyresnių klasių mokiniai kur kas dažniau siūlo užsiimti fiziniu aktyvumu kartu. Šiuo atveju jaunesni mokiniai savo... [toliau žr. visą tekstą]The object of research – Students of social support, physical environment and learning outcomes interfaces with physical activity The aim – Set of 8-9 grade students of social support, physical environment and learning outcomes relationship with physical activity. Objectives: 1. Set the physical activity of students by gender and age. Third set of physical environment on students physical activity. 2. Identify social support impact on student physical activity. 3. Identify the physical environment on students' physical activity. 4. Identify students' learning achievements of different aspects of physical activity. 5. Set physical activity, social support influence the physical environment and the students' learning achievement between the interfaces. Conclusions: 1. The study found that 52,2 rate surveyed students were physically active and 47,7 rate passive, were more physically active males (p<0,05), physical activity, older students more engaged. Most of the students' physical activity per week to 2 – 3 times a week. Physically active students of their subjective physical activity and capacity by higher scores. 2. It was found that parents support and support younger pupils and boys physical activity (p<0,05). The study found that parents are less interested in the older child's physical activity than younger, but also guys supporting physical activity less than girls. The analysis of students' friends and influence physical activity found that older students much more... [to full text]
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Sequerra, Ruth. "The FA Women's Super League : framing developments in elite women's football." Thesis, Sheffield Hallam University, 2014. http://shura.shu.ac.uk/17163/.
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In 2009, the Football Association (FA), the national governing body of football in England, announced its plan to introduce the country's first semi-professional women's elite league. Launched in 2010 as the FA Women's Super League (FA WSL), its introduction provided both an opportunity to research whether this evidenced a change of position for the women's elite game within footballing narratives and also to examine the place of the FA within these. This study adopted a critical sociological feminist approach to deconstruct the assumptions, values and practices that frame the female game and the introduction of the FA WSL, while providing new insights into the role of the sport's governing organisation in defining elite women's football. Through observations at matches and interviews with people working within the women's game, an examination of the development and introduction of the FA WSL was undertaken, with valuable early insights provided into the first three years of the new League. The study identified that the introduction of the FA WSL was impacted upon by the complex, closed and gendered nature of the FA's organisational structure. The new League adhered to traditional societal concepts of hegemonic masculinity, heteronormativity and liberal approaches to gender equality. The study also found that the new elite women's structures required the clubs who gained entry into the FA WSL to adhere to commercialised, spectacularised and commodified values which dominate the men's game and neo liberal societal narratives. The increased inclusion of females into elite football structures did not profoundly disrupt traditional discourses or provide evidence of a fundamental challenge to gender inequality in the game.
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ZHAN, RONG-FA, and 粘榮發. "ZHAN, RONG-FA." Thesis, 1985. http://ndltd.ncl.edu.tw/handle/35887291548835672611.
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Röbel, Richard. "Passages: Tombeau en fa dièse." 2017. https://slub.qucosa.de/id/qucosa%3A8013.
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Passages
Tombeau en fa dièse
für sieben Vokalsolisten
mit Textfragmenten
von Michel de Montaigne und Étienne de La Boitié
für AUDITIVVOKAL
UA: 10. Dezember 2015 Deutsches Hygiene-Museum Dresden
Partitur
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LIN, ZIH-CHAO, and 林子超. "The study Yang Fa Calligraphy." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/u3p49z.
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碩士國立臺灣藝術大學
書畫藝術學系
107
So far, there are no treatises on Yang Fa, one of the Eight Eccentrics of Yangzhou, and his calligraphy works and paintings. Historical records about him is sparse, while most of the relevant articles and passages gleaned from journals and books are either dubious or incomplete. Therefore, in this paper, I tried to fully reconstruct the biography and work of Yang Fa, based on extant studies. There are five chapters. Chapter 1 explains how, in the beginning of my study, I gathered all the scattered information and produced a catalogue. Chapter 2 addresses the many problems related to Yang’s life and his courtesy name (zì) and art names (hào) arising from studying the signature and stamp on his works, and also probes into Yang’s association. Chapter 3 investigates the influence of early generations on Yang’s calligraphy – mainly the period from the late Ming dynasty to the middle Qing dynasty, but also as early as the stone inscriptions from Han dynasty – and the influence Yang had on calligraphers from the late Qing dynasty. Chapter 4 summarizes the artistic achievements of Yang Fa and analyzes forged works found on the market. Chapter 5 is the conclusion of my entire study. The main scripts Yang used in his works are seal and clerical scripts; running and cursive scripts are less common and only appear in some of the paratext and signature. His paintings are also few in number. Moreover, literature on Yang Fa is full of mistakes and there are a lot of controversies in regard to the circulation of his works, which is why I decided to analyze his signature and stamp as a way to determine the chronology of his works, to distinguish real and forged works, and to establish his position in history.
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Wojcik, Jennifer. "The Effects of High Protein Diets on Metabolic Syndrome Parameters in the fa/fa Zucker Rat." 2014. http://hdl.handle.net/1993/24049.
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Despite inconsistent results in the literature, high protein diets are being promoted for the management of metabolic syndrome parameters primarily due to their proposed favorable effects on weight loss. Therefore, lean and fa/fa Zucker rats were given normal and high protein diets with varying protein sources for 12 weeks. A high protein diet with a mixture of animal and plant protein sources was the most effective for improving metabolic syndrome parameters, specifically insulin resistance and hepatic steatosis. A high protein soy diet was the second most effective diet, while a high protein casein diet demonstrated no benefits compared to the other two high protein diets and minimal benefits compared to a normal protein casein diet. Interestingly, high protein diets did not affect body weight regardless of protein source. These findings suggest that the source of protein within a high protein diet is critical for improving metabolic syndrome parameters and that improvements can be observed independent of weight loss.
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Chiu, Wei-Ting, and 邱緯婷. "Development of FA/GGBFS Geopolymer Concrete." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/5e48n3.
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碩士國立臺北科技大學
土木工程系土木與防災碩士班
106
Iron blast-furnace slag is a by-product produced by the steel plant during the iron making process, and fly ash is a major by-product of coal-fired power plants. Every year, a large amount of blast-furnace slag and fly ash produced. With great difficulty, if it is disposed of as waste, it will not only be environmentally unfriendly, but will also cost a lot of costs. If blast-furnace slag is water-quenched cooling, grinding into fine powder and adding to concrete can replace part of the cement, it is generally considered that the concrete can be made denser and the durability is increased. The same is true for fly ash, which saves cement consumption. However, in order to make fuller and more efficient use of waste resources, this study attempted to produce geopolymer based on fly ash and blast-furnace slag, it is expected to develop cement-free concrete. According to the experimental results, a slurry of fly ash and geopolymer material ratio of 1, the strength of it can be up to 253.9 kgf/cm2 in 28 days. A slurry of blast-furnace slag and geopolymer material ratio of 1 and the performance is better, the strength of it can be up to 578.2 kgf/cm2. However, when gravel was separately added to make fly ash and blast-furnace slag geopolymer concrete specimens, the 28-day strength was only 148.8 kgf/cm2 and 229.7 kgf/cm2, respectively. It is initially known that the key factors may be in the gradation of coarse aggregates and will be discussed in subsequent research.
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Xu, Yong-Qin, and 許永欽. "kung t''ung yan fa tsai kung p''ing chiao i fa chih t''an t''ao." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/43770127095918103386.
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HSU, CHIH-PING, and 徐治平. "Systemic Role of Proline-Directed Protein Kinase FA (PDPK FA) in Various Types of Human Leukemia Cells." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/09264794861989891565.
Full textAbstract:
博士國立清華大學
生命科學系
89
Summary: The potential functional role of PDPK FA in various types of human leukemia cells was explored by investigating the effects of partial inhibition of this kinase on human acute lymphoblastic leukemia (Jurkat), acute myeloblastic leukemia (HL-60) and chronic myeloid leukemia (K562) cells by introducing antisense expression vector into these leukemia cells. In the stable antisense clones of Jurkat, HL-60 and K562 cells with specific suppression of PDPK FA exhibited growth retardation, poor clonogenic growth in soft agar and loss of serum independence. This is the first indication that suppression of PDPK FA is able to inhibit the malignant growth of various types of human leukemia cells. Furthermore, suppression of PDPK FA is also able to potentiate serum deprivation-induced apoptosis, suggesting an important role of this PDPK in regulating the resistance of leukemia cells to apoptosis. Moreover, suppression of PDPK FA is also able to dramatically enhance chemosensitivity of leukemia cells in response to various anticancer drugs. Mechanistic study further revealed that the enhanced chemosensitivity in these antisense clones is mainly due to potentiation of apoptotic induction. On the other hand, suppression of PDPK FA is also able to potentiate differentiation induction of leukemia cells in response to various differentiation-inducing agents. All the results presented in this thesis demonstrate the systemic functional role of PDPK FA in controlling malignant growth, apoptosis-, differentiation- and chemo-resistance of various types of human acute and chronic leukemia cells. Suppression of this multisubstrate/multifunctional PDPK may provide a new powerful strategy to serve as complementary therapy for human leukemia treatment.
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YANG, Chuan-Ching, and 楊銓慶. "Systemic Role of Proline-Directed Protein Kinase FA (PDPK FA) in Human Cervical, Prostate and Breast Cancers." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/05491026080119010086.
Full textAbstract:
博士國立清華大學
生命科學系
87
Proline-directed protein kinase FA (PDPK FA) was originally identified as the activating factor of type-1 protein phosphatase/glycogen synthase kinase-3a but has subsequently been demonstrated as a multisubstrate PDPK involved in the regulation of diverse cell functions. However, the systemic functional role of PDPK FA in human cancers remains largely unknown and is going to be the central theme of this thesis. The PDPK FA-specific antibody was firstly produced and characterized, which could efficiently and specifically immunoblot and immunoprecipitate PDPK FA from various human tissues and cells. By using this specific antibody, the expression of PDPK FA was found to be overexpressed many-fold in human cervical carcinoma tissues relative to normal control, suggesting an association of PDPK FA with human neoplastic disease. In human cervical carcinoma HeLa cells, it was further demonstrated that the activity of PDPK FA was duly controlled by protein overexpression and enhanced tyrosine phosphorylation, which is involved in the regulation of late mitosis. The observation was next extended to human prostate carcinoma cells. In order to further identify the functional role of PDPK FA in carcinoma cells, a specific PDPK FA antisense expression vector was constructed and transfected into human prostate carcinoma PC-3 cells. The stable antisense clones were selected and characterized, which exhibited cell growth retardation, impaired colony formation and loss of serum and anchorage-independent growth, demonstrating that specific antisense suppression of PDPK FA is sufficient to block proliferation and transformation of human prostate carcinoma cells. Moreover, specific antisense suppression of PDPK FA was also demonstrated to be sufficient to enhance chemosensitivity of various anticancer drugs and to potentiate apoptotic induction, demonstrating a primary essential role of PDPK FA in the regulation of proliferation, transformation, drug resistance and apoptosis of human cancer cells. In the final part of this thesis, the overexpression of PDPK FA was found to be systemically overexpressed in both tumors and lymphocytes of human cervical, prostate and breast cancer patients, suggesting a systemic role of PDPK FA in various human cancers. The results presented in this thesis may provide a hopeful clinic target for early cancer detection, prevention and treatment of various human cancers.