Dissertations / Theses on the topic 'Facteur de capacité'
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Mejdoub, Nacim. "Évaluation du facteur de transfert pulmonaire et de la capacité résiduelle fonctionnelle chez le nourrisson : méthode dynamique." Compiègne, 1997. http://www.theses.fr/1997COMP1027.
Full textCardoso, Bueno de Camargo Lívia. "Le rôle des vésicules extracellulaires dans la capacité invasive du cancer du sein : les fonctions de la famille des facteurs de transcription NFAT." Sorbonne Paris Cité, 2016. http://www.theses.fr/2016USPCC093.
Full textExtracellular vesicles (EVs) represent an important means of cell communication, through which cells can exchange functional mRNAs, microRNAs and proteins, amongst other molecules. During the past few years, the understanding of their role in cancer onset and progression has been largely developed. In this work, we approach the role of EVs in changing the invasive profiles of breast cancer cell lines. We were specifically interested in studying whether the opposite effects of the members NFAT1/NFAT5 and NFAT3 (members of the Nuclear Factor of Activated T cells family of transcription factors) in breast cancer cell motility could be linked to EV function in modulating cell invasiveness. While NFAT1 and NFAT5 are expressed by more invasive breast cancer cell lines that do not express the estrogen receptor alpha (ER alpha -), NFAT3 is expressed by cell lines with less aggressive profile, that are ER alpha +. To study the possible transfer of these opposite effects of NFAT factors through EVs, highly invasive (MDA-MB 231) and poorly-invasive (T47D) breast cancer cell lines were treated with each other's EVs. We have observed that an increase of invasion is induced through EVs secreted by MDA-MB 231. EVs secreted by T47D, on the other hand reduce invasiveness. Moreover, NFAT3 expression in T47D is an essentiel aspect in this second type of response, since when its expression is inhibited in these cells their EVs no longer have the power to reduce MDA-MB 231 invasiveness. We also show that EVs originated from T47D induce the active transcription of TGFbetal ir the recipient MDA-MB 231 to blunt cell nnotility. These results were extended in vivo, where we have demonstrated that T47D EVs are able to reduce primary tumour size and decrease metastasis formation in nude mice injected with human MDA-MB 231 D3H2LN cells in the mammary fat pad. Similarly to our in vitro results, NFAT3 expression in the EV producing cells was shown to be key for their EVs to present these effects. Furthermore, we could also observe TGFbetal sera levels increased in the mice where the treatment was effective, making this molecule a potentiel candidate for following treatment efficiency. Our findings suggest that EVs could represent a possible means of inhibiting the invasion of aggressive cancer cells, and therefore may be an attractive option to decrease tumor progression and metastasis in patients
Lardon, Arnaud. "Les facteurs prédictifs de douleur rachidienne commune chez les enfants et les adolescents." Thesis, Paris 11, 2015. http://www.theses.fr/2015PA113007/document.
Full textSpinal pain is a major health problem with socio-economic impacts. Back pain starts early, during childhood, the prevalence increases with age, particularly during puberty, to reach a similar level to that found at adulthood, around the age of 20. Despite the high prevalence of this condition, predictors for the first episode or for a recurrent episode are not known. The aim of this thesis is to explore different potential predictors of back pain during childhood and adolescence. A first literature review showed an association between puberty and back pain. The causality criteria described by Bradford- Hill, e.g. strength of the association, consistency across studies and dose -response are also present. Unfortunately,, it is not yet possible to conclude whether there is a temporal aspect as well; for temporality being the most important criterion. The second literature review showed a positive association between muscular endurance in extension and back pain, whereas no association was found between muscle strength in trunk extension and spinal pain. The available literature does not allow us to conclude about the potential association between aerobic capacity and back pain. The third study is a prospective study, in which children were followed during ten months. This study did not reveal any association between aerobic capacity, body composition and back pain. In conclusion, two factors are associated with back pain, puberty and low muscle endurance. Future research in this area should focus on the causal relationship between these factors and back pain
Hamlaoui, Madani. "Capacité portante des fondations superficielles pour géomateriaux avec modèles plastiques non associés." Thesis, Lille 1, 2015. http://www.theses.fr/2015LIL10146.
Full textIn associated plasticity, i.e. with the normality law, Prandtl-Hill analytical solution gives the exact limit load of a punch on a semi-infinite massive of foundation with Mohr-Coulomb model. However, it is experimentally recognized that geomaterial shave a non-associated behavior, what means that in reality the value of the limit load is only an estimation.In this work, it is proposed to fill this lack in addressing the problem of the bearing capacity of a shallow foundation, when the low of plasticity is no-associated. On the basis of numerical simulations and an extension of the limit analysis method to materials with non-associated laws by the bipotential approach, de Saxcé (1992), we proposed an approximated analytical solution by a variational method and we compared to Drescher-Detournay formula (1993) and numerical results
Zhu, Chaobin. "Rôle du facteur de croissance IGF-1 (Insulin-Like Growth Factor-1) sur la progression tumorale invasive et métastatique du mélanome : approches anti-tumorales basées sur l'inhibition du facteur IGF-1." Thesis, Paris 11, 2015. http://www.theses.fr/2015PA11T012.
Full textMetastatic melanoma is the least common (5-7 %), but is responsible for most skin cancer deaths by its strong resistance to conventional anti-cancer treatments. Although immunogen, no effective treatment currently exists against this aggressive form, making urgent to find new therapeutic targets. In this context, we assessed whether the Insulin-like Growth Factor-1 (IGF-1) could represent a target of therapeutic interest in melanoma inhibiting the expression of IGF-1 by means of an episome-based vector encoding antisense IGF-1, in two cellular models: primary melanoma cells B16-F0 and metastatic B16-F10 (designated B16-F0mod and B16-F10mod when IGF-1 expression is inhibited).In experimental models in vivo, our results show that the reduction of IGF-1 expression induced a decrease of the melanoma cells tumorigenicity, generating smaller tumors under the skin (B16-F0 and B16-F10 in the C57BL/6 mice) and inhibiting totally (C57BL/6) or strongly (NSG mice) the developpment of B16-F10 lung metastases. We sought to understand whether this loss of tumorigenicity, following IGF-1 inhibition, was due to a change of immunogenicity/antigenicity of tumor cells and/or to intrinsic tumorigenic potential modification of metastatic tumor cells.1 / Immunization of mice C57BL/6 mice with B16-F0mod cells induces the formation of humoral lytic effectors in the presence of complement against the parental line, but also CD8+ effector cells capable of inducing tumor cells lysis in vitro and inhibiting tumor growth in vivo. Although the analysis of humoral and cellular pathways did not demonstrate IGF-1- dependent mechanisms involved in B16-F10 cells, immunization of C57BL/6 mice with B16 cells F0mod leads to skin tumor growth inhibition and a reduction in pulmonary metastases number, confirming the involvement of IGF-1 factor in tumor escape mechanisms of the immune system.2 / Our results also show that IGF-1 plays a direct role in the intrinsic tumorigenic potential of tumor cells. In addition to its effect on tumor cells proliferation, IGF-1 is involved in epithelial-mesenchymal transition (increased N-cadherin, vimentin, CD44 and CD29 markers), promoting the maintenance of tumor populations with stemness properties (Sox2, Oct3/4, CD44, CD24, ALDH activity side-population and ability to form spheroids). By this mechanism, IGF-1 promotes both migration properties and drugs efflux such as mitoxantrone, via ABC transporters, which partly explains the strong resistance of melanoma to conventional therapies.This work shows that the inhibition of IGF1/IGF1-R pathway might be a good strategy for the development of anti-tumor treatments against melanoma. In addition to developing immunotherapy strategies, blocking the IGF-1 pathway would also sensitize melanoma cells to conventional therapy and decrease the metastatic potential of tumor cells
Callier, Jacqueline. "La décomposition acido-basique comme facteur limitant de l'exercice musculaire : effets d'une alcalinisation exogène sur la capacité d'endurance a puissance sub-maximale et maximale du sujet sportif." Paris 5, 1991. http://www.theses.fr/1991PA05S018.
Full textBinti, Abd Jamil Roshamida. "Optimization of the capacity factor of energy ships for far-offshore wind energy conversion using weather-routing." Thesis, Ecole centrale de Nantes, 2022. http://www.theses.fr/2022ECDN0002.
Full textThe energy ship is a relatively new concept for offshore wind energy harvesting. It consists of a windpropelled ship that generates electricity using water turbines attached underneath its hull. Since the energy ship is not grid-connected, the generated energy is stored aboard (for instance, using batteries or through conversion to hydrogen using an electrolyzer). A key advantage of the energy ship is that it is mobile. Therefore, its trajectory can be optimized using weatherrouting in order to maximize energy production, which is the focus of this thesis. The analysis in the thesis is based on numerical simulations. The weather-routing software is a modified version of QtVlm in which the optimization objective has been replaced by the maximization of the energy production. The energy ship is modelled in the software by a velocity polar and a power production polar. The wind data is based on the ECMWF ERA-5 wind dataset. The energy ship concept is particularly well-suited for the harvesting of the wind energy conversion in the faroffshore. Therefore, the capacity factor of energy ships deployed in the North-Atlantic Ocean is investigated first. Results show that a capacity factor of 70% can be (annual average). It is similar to that of floating offshore wind farms which would be deployed in the same area. Energy ships may also be used for the power supply of islands and coastal communities. Therefore, the capacity factor of energy ships deployed nearshore is also investigated. Two case studies are considered: the island of “Ile de Sein” and the “Saint-Pierre-et-Miquelon” archipelagos. Results show that the capacity factor is in the order of 50%. In this case, it would be 10 to 20% smaller than that of offshore wind farms. The weather-routing optimization depends on physical (e.g. storage capacity, rated power) and numerical parameters. Sensitivity analyses are performed in order to understand their effect on energy production. Results show that the optimization algorithm in QtVlm tends to converge to local maxima. Therefore, future work should be directed towards the development of better optimization methods
Six, Vincent. "Analyse du comportement des colonnes ballastées : influence des conditions initiales." Lille 1, 2006. https://pepite-depot.univ-lille.fr/LIBRE/Th_Num/2006/50376-2006-Six.pdf.
Full textPaillot, Thomas. "Etude de composants MEMS RF pour les circuits hyperfréquences et millimètriques." Limoges, 2005. https://aurore.unilim.fr/theses/nxfile/default/4476a58f-9a3c-467d-93cf-45881d3a1e6a/blobholder:0/2005LIMO0040.pdf.
Full textThis work presents MEMS component applications for radio frequency and millimeter wave circuits. These components have been used for the realization of switch functions and also integrated to "classic" RF circuits, resonators and filters, in order to obtain frequency tunable circuits. Several circuits have been presented, low loss capacitive switches in Ka band, capacitive switches for high power applications and finally tunable resonators and filters. A particular study has been made so as to demonstrate microstrip tunable circuits. The measurements obtained on a two pole tunable filter using four MEMS variable capacitors show the potential of micro electromechanical components to realize high quality factor circuits
Vincent, Hugues. "Développement d'un modèle de calcul de la capacité ultime d'éléments de structure (3D) en béton armé, basé sur la théorie du calcul à la rupture." Thesis, Paris Est, 2018. http://www.theses.fr/2018PESC1038/document.
Full textTo evaluate the load bearing capacity of structures, civil engineers often make use of empirical methods, which are often manuals, instead of nonlinear finite element methods available in existing civil engineering softwares, which are long to process and difficult to handle. Yield design (or limit analysis) approach, formalized by J. Salençon, is a rigorous method to evaluate the capacity of structures and can be used to answer the question of structural failure. It was, yet, not possible to take advantage of these theoretical methods due to the lack of efficient numerical methods. Recent progress in this field and notably in interior point algorithms allows one to rethink this opportunity. Therefore, the main objective of this thesis is to develop a numerical model, based on the yield design approach, to evaluate the ultimate capacity of massive (3D) reinforced concrete structural elements. Both static and kinematic approaches are implemented and expressed as an optimization problem that can be solved by a mathematical optimization solver in the framework of Semi-Definite Programming (SDP).A large part of this work is on modelling the resistance of the different components of the reinforced concrete composite material. The modelling assumptions taken to model the resistance of concrete are discussed. And the method used to model reinforcement is also questioned. The homogenization method is used to model periodic reinforcement and an adaptation of this technique is developed for isolated rebars. To conclude this work, a last part is dedicated to illustrate the power and potentialities of the numerical tool developed during this PhD thesis through various examples of massive structures
Enette, Lievyn. "Faisabilité et comparaison d'un entrainement aérobie de type continu ou intermittent sur les capacités physiologiques, cognitives et la qualité de vie, chez des personnes âgées présentant un trouble neurocognitif majeur associé à la maladie d'Alzheimer." Thesis, Strasbourg, 2019. http://www.theses.fr/2019STRAJ054.
Full textAerobic training (AT) shows health benefits for older with Alzheimer disease, but the physiological mechanisms that explain these remain to be analyzed. The objectives of this work were to study the feasibility of continuous aerobic training (CAT) or interval aerobic training (IAT) over 9 weeks and to compare their effect on brain derived neurotrophic factor (BDNF) plasma level, aerobic fitness, cognitive capacities and quality of life (QoL) in older with AD. No significant changes in terms of BDNF plasma level and cognitive performance was measured but a significantly improvement of endurance parameters was found. QoL was improved after CAT. This work shown that CAT and IAT are both feasible and equally effective to improve aerobic fitness. CAT had a positive impact on QoL, but both aerobic training failed to induce significant BDNF responses and improve cognitive performances
Bleibtreu, Alexandre. "Rôle des capacités de croissance et de la résistance aux stress dans la virulence extra intestinale d’Escherichia coli : de l’espèce au clone." Paris 7, 2014. http://www.theses.fr/2014PA077244.
Full textThroughout long evolutionary time, we showed that at the species level the extra intestinal virulence is essentially explained by the number of virulence genes. Using a new collection, collected during the thesis, we have shown that mutations in the rpoS gene are essentially laboratory-acquired and the evolutionary history of rpoS is subjected to a pressure of purifying selection, that it respects the phylogeny of the species and that it follows a "source and sink" model. Moreover, the mode of acquisition is important. Strains responsible for pediatric community-acquired infections showed higher growth capacities officials pediatric nosocomial infection strains. We also showed that the ST131 clone had particularly high growth capacity may explain its spread in the community. In short evolutionary time, we studied vine isolates from a patient during a peritonitis with genetic and phenotypic microheterogeneity and different levels of RpoS. RpoS allele did not affect virulence. So it seems that across evolutionary time short growth capacities are predominant in the variations in virulence observed. Inactivation of virulence offset by increased resilience to stress must confer selective advantages in the unique : environment that is the peritoneal cavity during peritonitis E. Coli. Finally, data from the sequencing of complete genomes of isolates will better understand the mechanisms of microdiversité and its relationship with virulence
GUILBERT, BOURGOIS VERONIQUE. "Evaluation de la capacite de liaison du facteur willebrand au collagene par methode elisa." Lille 2, 1994. http://www.theses.fr/1994LIL2M296.
Full textRubinstein, Marianne. "La dynamique des capacités de production : le rôle des degrés d'utilisation des facteurs." Aix-Marseille 2, 1993. http://www.theses.fr/1993AIX24004.
Full textKompaore, Baowendsomdé Eliane Olga. "Les facteurs déterminants de la capacité à réussir l'innovation dans les PME manufacturières." Thèse, Université du Québec à Trois-Rivières, 2008. http://depot-e.uqtr.ca/1713/1/030054709.pdf.
Full textBenboubker, Lotfi. "Cellules souches hématopoi͏̈étiques du sang périphérique : caractérisation fonctionnelle et facteurs intervenant dans la capacité de mobilisation." Tours, 2002. http://www.theses.fr/2002TOUR3308.
Full textLeverrier, Céline. "Evaluation des capacités d'estimation de la force musculaire et influence de facteurs de perturbation." Caen, 2009. http://www.theses.fr/2009CAEN2076.
Full textThe aim of this work is the study of estimation capacities of muscular strength as well as the impact of disruptive factors. In order to answer this aim, 3 studies were realized without external feedback so as to carry out a diagnostic evaluation and analyse the reproducibility of estimation capacities as well as to quantify the effects of long and short-term disruptions. The recordings of mechanical parameters (isokinetic dynamometer), neurophysiologic (EMG) and different determined strength levels at the target-values of 25, 50 and 75% would allow studying the estimation capacities of muscular strength. First, different estimation capacities were underlined following the mode and velocity of tested muscular action. The reproductible characters of these estimations as well as the abilities of adaptation were established. A correction of the erroneous estimations in the dynamic mode is also observed. Second, following the submaximal isometric training protocol, a specificity of mode of muscular action and percentage of training was observed. Finally, in the shorter time, after a muscular fatigue exercise, the estimation capacities would adapt according to the contractile state of the muscle. On the other hand, they were strongly disrupted during the realization of the cognitive task implying so a cortical overload. The superior centers would seem to be the basis of estimation of muscular strength, with a contribution of peripheral mechanisms
Millet, Xavier. "Capacités cognitives résiduelles et facteurs d'optimisation des performances de mémoire dans la maladie d'Alzheimer." Thesis, Bordeaux 2, 2009. http://www.theses.fr/2009BOR21685/document.
Full textAlzheimer’s disease is characterised by severe memory deficits related to the inability to consciously recollect previously encountered information regarding place, people or events. However, some residual cognitive abilities could remain in Alzheimer’s disease allowing the patients to access these past experiences by non-conscious means of recovery. The main objective of this doctoral thesis is to investigate some residual cognitive abilities and the conditions that may optimise patients’ memory performances. The first study conducted provided results showing that implicit memory processes are preserved in Alzheimer’s disease including after quite long delays of about thirty minutes. Furthermore, through a meta-analysis including eighteen studies, we concluded that encoding conditions requiring generation or semantic elaboration processes are likely to optimise patients’ implicit memory processes. Lastly, we conducted a third study investigating the difference in visuo-spatial working memory abilities between men and women in Alzheimer’s disease. The results showing that male patients still present a greater ability than females to actively manipulate visuo-spatial information suggest that sex could figure among the numerous variables contributing to modulate the clinical manifestation of the disease. Despite the severity of the cognitive deterioration in Alzheimer’s disease, these studies illustrate the persistence of some cognitive abilities and also the conditions likely to optimise the enhancement of such residual abilities. These results may have potential clinical application dedicated to improve the cognitive rehabilitation of patients' memory deficits
Ross, Justin Henry. "Evaluating ultimate bridge capacity through destructive testing of decommissioned bridges." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 154 p, 2007. http://proquest.umi.com/pqdweb?did=1338919151&sid=8&Fmt=2&clientId=8331&RQT=309&VName=PQD.
Full textPrincipal faculty advisors: Michael J. Chajes and Jennifer Righman McConnell, Dept. of Civil & Environmental Engineering. Includes bibliographical references.
Gerome, Camille. "Les initiatives de transition comme facteur de développement des capacités territoriales d'adaptation aux effets des changements climatiques." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLV026/document.
Full textTo respond to social issues of adaptation to the effects of climate change, this thesis contributes to the understanding of adaptation capacity development processes. The main subject is the spontaneous transitional citizens dynamics. It is about a group of citizens wishing act locally for the development of their territory in a coherent way around shared values.This thesis helps to demonstrate the emergence and the development of innovative social practices. This is comparable to social innovations in transition arenas who reproduce characteristics of niches: protected and restricted space encouraging incubation. These social innovations, fostered by networking, cohesion and the sharing of values, contribute to the development of adaptability through a desire for transmission and a global dynamic of inclusion.Concretely, this study focuses on two transition initiatives similar in their intentions and different in their history. They participate in considering a new dynamic of society that is both spontaneous, autonomous and inclusive.By positioning itself neither "against" the territory and its institutions, nor "without" them, these transition initiatives represent remarkable alternatives to lead to more cooperative societies and more able to adapt to the effects of climate change
Lindström, Gustaf. "Is GSM-R the limiting factor for the ERTMS system capacity?" Thesis, KTH, Trafik och logistik, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-101811.
Full textMacchi, Lucie. "Facteurs prédictifs et caractéristiques des capacités de lecture d'enfants présentant des troubles du langage oral." Thesis, Lille 3, 2015. http://www.theses.fr/2015LIL30023.
Full textThis thesis is concerned with the reading abilities in children with specific language impairment (SLI). It aims to precise the process involved when these children read isolated words, by analyzing their written language abilities in relation to their spoken language abilities. Firstly, the main findings of the literature on this topic are presented. Then, four experimental studies conducted both in children with SLI and typically developing children are described. These studies deal with: (1) identification of isolated written words in reading aloud, (2) identification of isolated written words in silent reading, (3) written word comprehension, (4) and predictive factors of reading. The striking results of these studies indicate that, in written word identification in reading aloud, as well as in silent reading, children with SLI show an average delay of about three years, compared to reading control children. As a group, their phonological procedure is less efficient than their orthographic procedure. However, interindividual heterogeneity remains high. The children with the most severe impairment in language production at the phonological level are those with the greatest deficit in the phonological reading procedure. Isolated word comprehension, as for it, appears to be costly in terms of processing abilities. Finally, children with SLI display the same predictive factors of reading as typically developing children, with the exception of inconsistency in speech production, which is a reading predictor specific to children with SLI. Further research about this inconsistency would be useful
Vimalaraj, Panchalingam. "A simple equation for bearing capacity of a shallow foundation." abstract and full text PDF (free order & download UNR users only), 2006. http://0-gateway.proquest.com.innopac.library.unr.edu/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:1438933.
Full textLOISEAU, CELINE. "Modelisation et caracterisation de la capacite activatrice de polymeres hydrosolubles vis-a-vis du facteur xii (facteur hageman) en milieu purifie ou plasmatique (systeme contact de la coagulation)." Cergy-Pontoise, 1996. http://www.theses.fr/1996CERG0016.
Full textHillhouse, William Jeffrey. "Application of motor capacitors to improve facility power usage in the industrial setting." Texas A&M University, 2005. http://hdl.handle.net/1969.1/4315.
Full textVitkova, Anna. "Decrease in resource capacity as the factor of minimization of technogenic loading." Thesis, Видавництво СумДУ, 2011. http://essuir.sumdu.edu.ua/handle/123456789/10384.
Full textGhislin, Stéphanie. "Contrôle épigénétique sur les capacités invasives des cellules tumorales dans le mélanome humain." Paris 7, 2011. http://www.theses.fr/2011PA077224.
Full textThe chemotherapy currently used to treat metastatic melanoma has a very low efficiency, the study of mechanisms involved in its development is essential to develop new therapies. However it is complicated due to the existence of high plasticity, with conversions between proliferative phases and invasive phases, the latter being associated with dedifferentiation. We first showed that melanoma cells cultured in three dimensions in a defined medium for growing neurospheres were polarized to a state invasive and overexpressed Oct4 and Nanog. To explain the observed transcriptional dysregulation, we analyzed the epigenetic changes which take place in these conditions and showed significant changes at the level of histone H3. We then identified the protein PHF19 as an important factor in the phenotypic switching, but not involved in regulating the expression of Oct4 and Nanog, suggesting the involvement of at least another factor. Thus we have shown that P-Akt is an inhibitor of the expression of these two genes and an activator that of PHF19, thus suggesting a central role of Akt pathway in the phenotypic conversion. We also sought to identify some molecules involved in extra vasation of melanoma cells. We have shown that melanoma lines can express JAM-A and/or JAM-C, molecules involved in transendothelial migration in lymphocyte. Thus we have shown that JAM-A inhibits the transmigration of melanoma cells while JAM-C favors
Kompaore, Baowendsomdé Eliane Olga. "Les facteurs déterminants de la capacité à réussir l'innovation dans les PME manufacturières /." Thèse, Trois-Rivières : Université du Québec à Trois-Rivières, 2008. http://www.uqtr.ca/biblio/notice/resume/30054709R.pdf.
Full textShi, Ming. "Simulation monte carlo de MOSFET à base de materiaux III-V pour une électronique haute fréquence ultra basse consommation." Phd thesis, Université Paris Sud - Paris XI, 2012. http://tel.archives-ouvertes.fr/tel-00666876.
Full textPoplin, Gerald Scott. "Aerobic Capacity and Injury Risk: Determining Associative Factor of Injury Among Emergency Service Employees." Diss., The University of Arizona, 2012. http://hdl.handle.net/10150/255164.
Full textGouthon, Polycarpe. "Entraînement et capacité aérobie dans une stratégie de prévention des risques cardiovasculaires chez des adolescents béninois." Bordeaux 2, 2001. http://www.theses.fr/2001BOR28950.
Full textThe present study examines the effect of training on aerobic capacity and physiological factors associated with cardiovascular risk in Beninese youngsters aged 13 to 18 years. The population consisted of 359 adolescents of both sexes living in Porto-Novo. The data made it possible : 1) to establish a set of norms regarding maximal aerobic power (MAP) and aerobic endurance assessed by the time limit of maintaining maximal aerobic speed (tlim100) ; 2) to demonstrate the factors of aerobic capacity and several physiological factors associated with cardiovascular risk ; 3) to assess the effects on aerobic capacity of school physical education with three training modes over 12 weeks with one or two sessions per week. - Evolution of aerobic capacity in relation to age had the same tendancies as noted in other countries, but the values differed from those observed in Canada, Belgium and France regarding tlim100 (369s to 493s in Beninese boys versus 316 s to 379 s in French ones). - The contribution of biometric and cardiovascular factors in predicting shuttle VO2max was significant (R2 = 0. 54, p < 0. 05) while lipidic factors were not. - Training at inframaximal intensities ( < 95 % Fcmax) is slightly less efficient than intensive training (85 % - 120 % MAS) for improving MAP (4. 7 % versus 6. 8 %), but it is more appropriate for preventing cardiovascular risk in youngsters, since it reduced body fat, heart rate at rest, the blood pressure gradient during exercise (b = 0. 39 versus b = 0. 36 at test and retest) and electrocardiographic abnormalities. These data confirm the influence of environmental factors as being thermal stressors influencing the expression of aerobic capacity, and the specificity of the effects of training
Garnier, Denis. "Analyse par la théorie du calcul à la rupture des facteurs de réduction de la capacité portante de fondations superficielles." Phd thesis, Ecole Nationale des Ponts et Chaussées, 1995. http://tel.archives-ouvertes.fr/tel-00529455.
Full textLaupèze, Béatrice. "Altération de la différenciation, de la capacité fonctionnelle et de la survie des cellules dendritiques myéloi͏̈des : : facteurs intrinsèques et environnementaux." Rennes 1, 2001. http://www.theses.fr/2001REN10154.
Full textHeron, Matthew Joseph. "Assessment of time-dependent capacity of driven piles in Ohio soils." University of Dayton / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1556303954380124.
Full textHolmgren, Henrik, Colin Platt, and Johan Svennerholm. "Capacity Performance Measures in International Airline Alliances : The case of Star Alliance." Thesis, Jönköping University, JIBS, EMM (Entrepreneurship, Marketing, Management), 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-1301.
Full textBackground
Strategic alliances have become increasingly popular within the business world, they can be seen as a way to improve the total output of the firm. Over the last 10 years, the industry endured trying times, the most notable being the events of September 11, 2001. That event drastically changed airline traveling all across the world. It also showed the importance of collaborations in order to stay competitive. Star Alliance began in 1997 and has since then grown into
the world’s largest airline alliance with a total market share of 25.1%.
Purpose
The raison d’être of this study is to quantify and analyze the augmentation of load factors over time, in terms of distribution, as they pertain to capacity performance of allied carriers within Star Alliance.
Method
In order to fulfill the purpose, a deductive approach to the research has been taken. Furthermore, due to the nature of the data, a quantitative approach has been used within. Two hypotheses will be stated and several research questions as well.
Result
It can be clearly seen that distribution of load factors has transformed during the years. There is a shift in both the skewness and the kurtosis of the distributions that can be seen when examining the frequency distribution charts. The kurtosis increases and the skew decreases, measures that are positive for the airlines, while the anomalies of 0% and 100% load factor have remained stable throughout the years. A general increase in the average load factors has also been seen.
Conclusion
By analyzing the empirical findings, it is clear that the load factor of the allied members has increased and that the proportion of the denied boardings decreased in relation to the average load factor. This means that the alternative hypothesis was accepted in the first hypothesis and that the second alternative hypothesis was accepted in the second hypothesis. The research also reveals a generally increased mean which together with the changes in the skew and kurtosis lead to an acceptance of the beta distribution. Furthermore, higher load factors were shown to have a strong correlation with the increase in efficiency and decrease in overselling.
Rauffet, Philippe. "Prise en compte des facteurs formels et contextuels dans la gestion des capacités organisationnelles : application aux organisations matricielles." Phd thesis, Ecole centrale de nantes - ECN, 2010. http://tel.archives-ouvertes.fr/tel-00562580.
Full textPeriac, Fabrice. "Les concepts de "diversité culturelle" et de "capital social" comme facteurs explicatifs de la capacité d'innovation des organisations et des territoires." Thesis, Saint-Etienne, 2014. http://www.theses.fr/2014STETT109/document.
Full textWe investigate whether tt is salient to çonsider the concept of "cultural diversity" (CD) and/or "social capital" (SC) as explanatory factors of organisations' and territories' innovative capacity (IC). The starting point of our demonstration is Reagans & Zuckerman's article (2001), who shows that at the level of work groups, CD does not have a direct impact on IC but rather an indirect impact, mediated by two variables of SC cohesion and external range. We propose that the concept of "bonding-and-bridging social capital"' (BBSC)- combination of the two SC variables- constitutes a salient explanatory factor of work group's IC. Through an interdisplinary literature review we show how and why this more complex pattern interaction can be extended at the level of organisation, territories, and territory -industry (Tl). We carry out two empirical analyses to test our hypotheses. The first study concerns Tl level. lt uses EPO patent date to reconstitute the co-inventor's network of 85 Tls of the EUI5 in the electric equipment industry. We evaluate BBSC and IC in each TI, and we test their interaction econometrically. Result.s confirm the existence of a positive impact of BBSC on Cl, and show thal cohesion stimulates the quantity or patents, while extemal range stimulate the sustainable and collective orientation of patents. The second analysis concerns organisation level. It uses a set of unique data collected from 104 French SMEs. Results broodly confirm our hypotheses although the empiricaI frame allows to test only a small part of the model
Furlan, Alessandro. "Rôle du facteur de transcription Ets-1 dans les capacités invasives et angiogéniques de cellules cancéreuses mammaires : implications dans la tumorigenèse mammaire." Lille 1, 2007. https://pepite-depot.univ-lille.fr/LIBRE/Th_Num/2007/50376-2007-Furlan.pdf.
Full textGueye, Lamine. "Facteurs déterminants de la capacité de remboursement du crédit agricole à la CNCAS, cas de la riziculture dans la vallée du fleuve Sénégal." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0004/MQ44715.pdf.
Full textFischmeister, Jindra. "Réussite ou échec scolaire chez les enfants de mêmes capacités intellectuelles : étude de la place de certains facteurs extra-intellectuels." Paris 10, 1994. http://www.theses.fr/1994PA100145.
Full textIntellectual competence alone is not sufficient for school achievement. Other factors intervene; two of them are the "locus of control" (rotter, 1966) and the self-esteem. My study examined the relation between high or poor school achievement and these two personality and social-cognitive variables, for they take their origin in the interaction of the individual with his environment. The age of the subjects and their sexes can affect this relationship. The culture, French or other, and the context, favorable or disfavorable, can also have an effect on this relation. For to test the efficiency of all these parameters, I have chosen three groups of subjects. Group 1, second grade children, favorable context, 24 boys, 29 girls, group 2, second grade children, disfavorable context, 9 French boys, 9 French girls, 15 boys and 16 girls of other cultures; croup 3, seventh grade children, favorable context, 23 boys and 30 girls. Their intellectual competence was evaluated with a measure of "g" and a vocabulary test. For the locus of control used the pns-ie from Nowicki and Duke (1974) and the cns-ie from Nowicki and Strickland (1973); the test of person (1969) for the self-esteem. My results indicate that intelligent pupils are not always successful at school. This phenomenon becomes stronger with the age for the boys. Like that, in the group 3 no relationship was found between the both intelligence scores and school performance for the boys, and a strongly significant relationship held for the girls (***and**). I didn't find the internal more than the external control in "locus of control" being associated with success in school performance, excepted for the girls of the group 3 (significant to **)
Samozino, Pierre. "Capacités mécaniques des membres inférieurs et mouvements explosifs. Approches théoriques intégratives appliquées au saut vertical." Phd thesis, Université Jean Monnet - Saint-Etienne, 2009. http://tel.archives-ouvertes.fr/tel-00483683.
Full textMaldonado, Alvarado Pedro Gustavo. "Facteurs déterminants du pouvoir de panification de l’amidon de manioc modifié par fermentation et irradiation UV." Thesis, Montpellier 2, 2014. http://www.theses.fr/2014MON20004/document.
Full textThe breadmaking ability of sour cassava starch, cassava starch modified by fermentation and UV irradiation, have not been yet fully elucidated. The influence of genotype and postharvest treatments on expansion ability of sour cassava was the objective of this work. Thirteen cassava genotypes have been studied. All genotypes proceeded from Colombia. Two altitudes of origin (1000 m. and 1700 m.a.s.l. refered to respectively as lowland and highland), fermentation treatments (0 or 30 days) and drying treatments (oven or sun) were considered. Analyses of the granule size, RVA pasting behavior and intrinsic viscosity were analysed as indicators of breadmaking ability. Results showed that post-harvest treatments were prevailing factors in improving breadmaking ability while the genotype factors had a smaller influence. Among post-harvest treatments, fermentation had a greater influence than sun-drying on these indicators, in particular on starch granular structure. The combination of both treatments was needed to obtain a high capacity bread. Furthermore, the altitude of origin of cassava genotypes was observed to affect the fermentation process: different sensitivities to fermentation were found between granules of lowland and highland (exocorrosion and endocorrosion, respectively). Highland genotypes showed a better breadmaking ability. Other influencing factor related to genotype was the amylose content measured by DSC: it negatively influenced the expansion of the dough, probably due to the formation of amylose-lipid complex. As a conclusion, the combination of cassava genotypes (mainly amylose content) and post-harvest treatment is key for expansion ability of sour starch. This knowledge is a first, essential step to provide quality standards for sour starch, targeted particularly for use in gluten-free products
Loustau, Emilie. "Effet des facteurs environnementaux sur la nature des EPS, la capacité de sorption du cuivre et le potentiel de résilience de biofilms phototrophes simplifiés." Thesis, Toulouse 3, 2019. http://www.theses.fr/2019TOU30148.
Full textPhototrophic biofilm, the main benthic signature of fast-flowing rivers, provide an important number of ecosystem services related to self-purification mechanisms (nitrates, pesticides, metal contaminations, etc.). However, their functioning is strongly disturbed by the increasing anthropogenic pressures, particularly by the presence of traces metals (TM) or the sequential interruption of surface flow. In the context of global change, the response of phototrophic communities should be considered for river management, in term of chemical and ecological properties. The aim of this thesis was to understand the physiological responses of benthic phototrophic microorganisms to environmental parameters involved in global change (light, temperature, phosphorus) as well as their response to a multi-stress combining the exposure of biofilms to TM (Cu and Zn, alone or in cocktail) by the prolonged drying of biofilm. Physiological responses of biofilm (biomass, photosynthetic activity and EPS production (extracellular polymeric substances)) were studied to analyze the tolerance and resilience capacities of communities. Three benthic phototrophic species were chosen: the cyanobacteria Phormidium autumnale, the diatom Nitzschia palea and the green algae Uronema confervicolum. Cultures of biofilm in free surface flow microcosms (hydraulic mini-channels) allowed to control all the experimental parameters. The first step was to develop a method for EPS extraction from the biofilm matrix while preserving the cell integrity of phototrophic microorganisms. Subsequently, the study of physiological responses of monospecific phototrophic biofilm exposed to Cu or/and Zn showed different sensitivities of phototrophic species. Then the sorption capacity of Cu by these species depended on environmental parameters, via the modulation of EPS production and composition. Finally, the double-stress characterised by Cu exposition followed by drying biofilm induced also resilience responses when rewetting, modulated by the environmental parameters. Overall, the monospecific phototrophic biofilms studied present different tolerance and resilience capacities by modifying the abundance and composition of EPS produced
Jamali, Shojaeddin. "Assessing load carrying capacity of existing bridges using SHM techniques." Thesis, Queensland University of Technology, 2019. https://eprints.qut.edu.au/134484/1/Shojaeddin_Jamali_Thesis.pdf.
Full textHOELTGEBAUM, HENRIQUE HELFER. "FORECAST OF THE JOINT DENSITY OF WIND CAPACITY FACTOR THROUGH THE USE OF A MULTIVARIATE GAS MODEL." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2015. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=25286@1.
Full textCOORDENAÇÃO DE APERFEIÇOAMENTO DO PESSOAL DE ENSINO SUPERIOR
PROGRAMA DE EXCELENCIA ACADEMICA
Neste trabalho usamos o arcabouço dos modelos GAS para gerar previsões conjuntas de fator de capacidade eólico, pertencentes a diferentes usinas localizadas em áreas geográficas distintas. Esses cenários são insumos para gerar uma distribuição de fluxo de caixa associada a um portfólio de contratos atrelados aos parques eólicos em questão. Inicialmente modelamos as densidades marginais via um modelo GAS, supondo densidade Beta. De maneira a capturar a estrutura de dependência entre esses fatores de capacidade, usamos uma cópula t-Student com a matriz de correlação também sendo atualizada via mecanismo GAS. Uma das contribuições importantes desse trabalho para o setor elétrico está na geração de cenários conjuntos apenas em um passo, evitando a necessidade de modelar variáveis transformadas e posteriormente transforma-las para retornar às suas respectivas escalas originais. Assim como é feito no caso supondo normalidade para as marginais. Como é sabido, exponenciar valores simulados a partir de uma densidade normal pode gerar resultados equivocados para fatores de capacidade eólico, e por propagação, isso pode afetar severamente as medidas de risco que são obtidas a partir da distribuição simulada de fluxo de caixa associada com o portfolio das usinas eólicas. Nossos resultados mostram que quando a dependência é levada em consideração, os fluxos de caixa tendem a ser maiores do que quando ignora-se a dependência.
In this work we use the framework of GAS models to generate joint forecasts for capacity factors of several wind plants belonging to different geographical areas. Such scenarios are then used as input to raise the distribution of cash flows associated with a portfolio of contracts attached to these wind plants. We first model the marginal density of each capacity factor using a GAS model with Beta density. In order to capture the observed dependence among these capacity factors, we use a copula t- Student with correlation matrix evolving through a GAS mechanism. One of the important contributions of our framework is that generation of scenarios is accomplished in just one step, avoiding the need of transforming back variables to its original scale, as it is the case under a Gaussian assumption for the marginals. As it is known, exponentiation of simulated Gaussian values can result in unrealistic sampling paths for the wind capacity factor, and by propagation, this can badly a ect the risk measures obtained from the simulated distribution of the cash flows associated with a particular portfolio of wind plants. Our results shows that when taking into account dependence the cash flows are higher than when ignoring dependence.
Chunkag, Viboon. "Three-phase power-factor correction using single-switch and parallel connected switching converters." Thesis, University of Bath, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.336239.
Full textAckebjer, Turesson Hampus, and Jesper Werneskog. "The Challenge of Providing Sufficient Grid Capacity for Electrification to Be a Key Factor in Achieving Climate Neutrality Until 2045 : A national and regional demand analysis investigating the future electricity demand and the grid operators' perspectives on large-scale electrification in Sweden." Thesis, Linköpings universitet, Energisystem, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-168135.
Full textLalander, Emilia, Mårten Grabbe, and Mats Leijon. "On the velocity distribution for hydro-kinetic energy conversion from tidal currents and rivers." Uppsala universitet, Elektricitetslära, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-195499.
Full textMeurier, Marie. "Les capacités dynamiques et leurs facteurs d'influence dans des contextes réticulaires : une étude exploratoire dans des réseaux territorialisés de la région PACA." Thesis, Aix-Marseille, 2014. http://www.theses.fr/2014AIXM2021.
Full textThe dynamic capability of an organization is its ability to constantly change and develop its resources, skills and processes to meet the needs of, and act upon its changing environment. However, the link between dynamic capabilities (DC) and inter-organizational relationships is rarely developed in the literature. Therefore, our dissertation deals with whether the network environment, through its structural and contextual characteristics, is suitable for the deployment and the development of DC. We question the processes that enable the deployment, detection and the creation of DC to understand whether DCs operate individually or in combination, and try to understand which DCs operate. Also, we question the inter-organizational nature of dynamic capabilities in territorial networks. Can DC be built or emerge from interactions in these networks? To answer these questions, we chose to conduct in-depth interviews in different territorial networks in the PACA region in France. Results of this empirical study show the need to take into account collective actions initiated by these networks of organizations, underline the role of proximity (broadly defined) as a means to deploy dynamic capabilities, and indicate the emergence of "network dynamic capabilities". Research results allow us to confirm the role of structural and contextual characteristics of territorial networks on the deployment and the creation of these capabilities and allow us to identify them in these contexts
Nikandrou, Paul. "Dynamic valuation model For wind development in regard to land value, proximity to transmission lines, and capacity factor." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/52812.
Full textThis electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references (p. 38-39).
Developing a wind farm involves many variables that can make or break the success of a potential wind farm project. Some variables such as wind data (capacity factor, wind rose, wind speed, etc.) are readily available in map form. However, other variables such as complications that may arise while working with landowners and local governments, and negotiating with utility companies for a power purchase agreement can be challenging, particularly when there are other competitors involved. This thesis discusses an analysis tool that could potentially be used by wind developers to look at large areas of land, and be able to predict when an area that previously was not considered to be attractive for wind development could suddenly become attractive if for instance the government passes a law mandating new subsidies that were not in existence before. The analysis tool would allow the user to input the new subsidy or any other new variable and see how this affects the feasibility of wind development in an area.
by Paul Nikandrou.
S.B.