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1

1964-, Murray Dennis L., ed. Pathogens, nutritional deficiency, and climate influences on a declining moose population. Wiildlife Society, 2006.

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2

Lynch, Sean Martin. Copper deficiency in the rat - sex differences and the influence of dietary factors. The Author], 1988.

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3

Fitch, Cindy. Factors associated with iron status among WIC infants and toddlers in rural West Virginia. USDA, Economic Research Service, 2007.

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4

Network, Tibet Information, ed. Delivery and deficiency: Health and health care in Tibet. Tibet Information Network, 2002.

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5

Kilbane, Mark T. Investigations into the presence and influence of thyroid associated factors in the natural history of breast disease. University College Dublin, 1998.

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6

M, Gould Jay, and Radiation and Public Health Project., eds. The enemy within: The high cost of living near nuclear reactors : breast cancer, AIDS, low birthweights, and other radiation-induced immune deficiency effects. Four Walls Eight Windows, 1996.

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7

1930-, Wu Bing-quan, and Zheng Jie, eds. Immune-deficient animals in experimental medicine. Karger, 1989.

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8

Rebafka, Franz-Peter. Deficiency of phosphorus and molybdenum as major growth limiting factors of pearl millet and groundnut on an acid sandy soil in Niger, West Africa. Universität Hohenheim, 1993.

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9

Magne, Ueland Per, and Rozen Rima, eds. MTHFR polymorphisms and disease. Landes Bioscience/ Eurekah.com, 2005.

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10

E, Groopman Jerome, Golde David W, Evans Charles H. 1940-, Hoffmann-La Roche inc, Smith, Kline & French Laboratories., and University of California, Los Angeles., eds. Mechanisms of action and therapeutic applications of biologicals in cancer and immune deficiency disorders: Proceedings of a Hoffmann-La Roche-Smith Kline & French-UCLA symposium, held at Keystone, Colorado, April 23-30, 1988. Liss, 1989.

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11

Ueland, Per Magne, and Rima Rozen. MTHFR polymorphisms and disease. Landes Bioscience, 2005.

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12

1911-, Riley Matilda White, Ory Marcia G, and Zablotsky Diane, eds. AIDS in an aging society: What we need to know. Springer Pub. Co., 1989.

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13

R, Egbring, McDonagh Jan 1942-, Seitz R, and International Conference on Factor XIII. (2nd : 1991 : Marburg, Germany), eds. Factor XIII: Second international conference, Marburg, July 9-10, 1991. Schattauer, 1993.

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14

S, Holmes Clarissa, ed. Psychoneuroendocrinology: Brain, behavior, and hormonal interactions. Springer-Verlag, 1990.

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15

Nichols, Eve K. Expanding access to investigational therapies for HIV infection and AIDS: March 12-13, 1990, conference summary. National Academy Press, 1991.

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16

Brahm, Amanda J., and Robert A. Hegele. Monogenic Chylomicronemia: Deficiency of Lipoprotein Lipase and Related Factors. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199972135.003.0033.

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Monogenic chylomicronemia is an autosomal recessive condition characterized by severely elevated fasting triglyceride that carries lifelong elevated risk of developing pancreatitis. The majority of cases are caused by mutations in the LPL gene encoding lipoprotein lipase, the enzyme primarily responsible for chylomicron clearance. Mutations in genes encoding associated proteins (APOC2, APOA5, GPIHBP1 and LMF1) may also present with a very similar phenotype. Current management, which includes restriction of dietary fat intake and standard pharmacologic interventions, has met with limited succes
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17

AIDS, psychosocial factors in the Acquired Immune Deficiency Syndrome. Thomas, 1985.

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18

Puntis, John. Iron deficiency. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198759928.003.0009.

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Iron deficiency is the most common nutritional deficiency in the world, affecting around 5 billion people mostly in developing countries. Risk factors in infants include low birthweight, high cow milk consumption, low intake of iron containing complementary foods, low socioeconomic status, and immigrant status. Developmental delay and poor educational achievement are among the long-term complications. Preventative strategies include promotion of breastfeeding, use of iron-fortified formula if breast milk not available, encouraging intake of iron-rich foods, vitamin C-rich drinks with meals to
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19

Marchetta, Anthony R. Role of soluble factors in the enhanced tumor resistance in protein-malnourished mice. 1997.

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20

García-Cazorla, Angels, and Rafael Artuch. Brain Serotonin Deficiency. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199972135.003.0032.

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Brain serotonin deficiency is a heterogeneous condition whose etiology remains unknown in the majority of cases. Strong evidence supports a major role for brain serotonin deficiency in common conditions such as depression and other psychiatric and cognitive disorders, which are probably due to interactions between genetic and environmental factors. Mendelian monogenic conditions leading to brain serotonin deficiency have also been identified, but they are rare. These diseases are associated with defects in other neurotransmitters (primarily dopamine), and it is difficult to link serotonin defi
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21

Living with Alpha-1 Antitrypsin Deficiency: Complete Guide to Risk Factors, Symptoms & Treatment Options. Hatherleigh Company, Limited, The, 2019.

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22

Moon, Martha Wellington. RISK FACTORS FOR HIV INFECTION IN RUNAWAY AND HOMELESS ADOLESCENTS IN SAN FRANCISCO (IMMUNE DEFICIENCY). 1995.

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23

Bartlik, Barbara, Janet Mindes, and Sheila Sperber Haas. Sexual Dysfunction Secondary to Micronutrient Deficiency (DRAFT). Edited by Madeleine M. Castellanos. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190225889.003.0008.

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Diverse micronutrient deficiencies can impair sexual function. The many recognized factors that can result in depleted vitamins and minerals include suboptimal diet, aging, toxins, malabsorption, and depleted soil. This chapter focuses on the generally unrecognized depleting effects due to a large and diverse variety of common pharmaceutical medications. Nearly half of all Americans take prescription drugs, frequently more than one, and many of them fall within this category and are discussed here. This chapter provides a detailed summary of clinical experience and research evidence for the de
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24

Schaffer, Susan D. ENVIRONMENTAL HIV/HBV RISK FACTORS RELATED TO PERCUTANEOUS AND MUCOCUTANEOUS EXPOSURE INCIDENTS IN NURSING STUDENTS (IMMUNE DEFICIENCY). 1995.

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25

(Editor), Jay M. Gould, ed. The Enemy Within: The High Cost of Living Near Nuclear Reactors : Breast Cancer, AIDS, Low Birthweights, And Other Radiation-induced Immune Deficiency Effects. Four Walls Eight Windows, 1996.

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26

Gava, Mathilda Zvinavashe. THE AIDS CRISIS: EXAMINING FACTORS THAT INFLUENCE USE OF CONDOMS BY YOUNG ADULT ZIMBABWEAN MALES (MEN, SHONA, IMMUNE DEFICIENCY). 1996.

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27

MTHFR polymorphisms and disease. Landes Bioscience/ Eurekah.com, 2005.

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28

Ueland, Per Magne. MTHFR Polymorphisms and Disease. Taylor & Francis Group, 2005.

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29

The Magnesium Factor. Avery, 2003.

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30

Geha, Raif, and FRED Rosen. Case Studies in Immunology: Factor I Deficiency. W.W. Norton & Company, 2010. http://dx.doi.org/10.4324/9780203853467.

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31

Riley, White Matilda, and Marcia G. Ory. AIDS in an Aging Society: What We Need to Know. Springer-Verlag, 1990.

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32

Charlotte, Mia Rnd. Factor X1 Deficiency Natural Remedy and Diet Plan. Independently Published, 2022.

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33

Bunch, Chris. Deficiency anaemias. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0279.

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This chapter addresses the diagnosis, investigation, and management of anaemia due to a deficiency in iron, vitamin B12, or folate. Erythropoiesis requires an adequate supply of iron for haem formation, as well as vitamin B12 and folic acid (folate) to support high levels of DNA synthesis, and a lack of any of these will result in anaemia. Iron-deficient anaemias are typically microcytic, while a deficiency in vitamin B12 or folate results in megaloblastic haemopoiesis and a macrocytic anaemia. Iron deficiency results from poor dietary iron intake, poor absorption, increased demands, blood los
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34

la Vecchia, Carlo, Cristina Bosetti, and Hans-Olov Adami. Thyroid Cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190676827.003.0025.

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While thyroid cancer incidence has globally increased over the last few decades, mortality has been steadily declining. This is essentially due to increased diagnosis of papillary thyroid cancer, due to the widespread use of ultrasound scan. Thyroid cancer is one of the few neoplasms more common in women than in men. Familial and genetic factors account for 5% to 15% of papillary or follicular neoplasms, and the association is even stronger for medullary carcinomas. Thyroid cancer risk is strongly related to benign thyroid diseases, particularly nodules and adenomas and goiter. The other major
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35

Roman, Eve, Tracy Lightfoot, Susan Picton, and Sally Kinsey. Childhood Cancers. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190238667.003.0059.

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This chapter addresses the wide range of histological and site-specific cancers that occur before age 25. It considers disease classifications, predisposing factors, and the epidemiology of the most common malignancies seen in children, and adolescents and young adults (AYAs). Cancer before age 25 is rare, accounting for < 2% of diagnoses in economically developed countries. The global burden of childhood cancers is, difficult to quantify, however, since over 80% of the world’s children and AYAs live in economically developing countries, where high morbidity/mortality from infectious diseas
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36

Moser, Janet. Von Willebrand factor: Measurement, changes during pregnancy, and inheritance of von Willebrand factor deficiency. 1994.

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37

Geha, Raif, and Fred Rosen. Case Studies in Immunology : Factor I Deficiency: A Clinical Companion. Norton & Company, Incorporated, W. W., 2010.

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38

Geha, Raif, and Fred Rosen. Case Studies in Immunology : Factor I Deficiency: A Clinical Companion. Norton & Company, Incorporated, W. W., 2010.

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39

Geha, Raif, and Fred Rosen. Case Studies in Immunology : Factor I Deficiency: A Clinical Companion. Norton & Company, Incorporated, W. W., 2010.

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40

Geha, Raif, and Fred Rosen. Case Studies in Immunology : Factor I Deficiency: A Clinical Companion. Norton & Company, Incorporated, W. W., 2010.

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41

Geha, Raif, and Fred Rosen. Case Studies in Immunology : Factor I Deficiency: A Clinical Companion. Taylor & Francis Group, 2010.

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42

Gluckman, Sir Peter, Mark Hanson, Chong Yap Seng, and Anne Bardsley. Magnesium in pregnancy and breastfeeding. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780198722700.003.0021.

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Magnesium in important for a wide variety of physiological processes; prominent among them is the control of muscle contractions, cardiac function, and carbohydrate metabolism. In pregnancy, low magnesium status is associated with hypertension, pre-eclampsia, gestational diabetes, leg cramping, and preterm labour. Magnesium has been used extensively in obstetrics to reduce uterine contractility in threatened preterm labour. Although current evidence does not support a requirement for magnesium supplementation for most pregnant women, those who are overweight, have risk factors for hypertensive
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43

Cassady, Charlyn Enid. AN ANALYSIS OF FACTORS INFLUENCING AIDS-RELATED OCCUPATIONAL STRESS, STATED WILLINGNESS TO PROVIDE CARE FOR THE PERSON WITH AIDS, AND THE STATED LIKELIHOOD OF PARTICIPATING IN AIDS RELATED WORK INCENTIVE PROGRAMS: A STUDY OF HOME HEALTH CARE WORKERS (IMMUNE DEFICIENCY). 1990.

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44

Wordsworth, B. P. Skeletal dysplasias. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0150.

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Bone is metabolically active throughout life and metabolic disturbances may have wide-ranging consequences that are not restricted to altering its mechanics. The study of some genetic bone diseases has already provided remarkable insights into the normal regulation of bone metabolism. Skeletal dysplasias are developmental disorders of the chondro-osseous tissues commonly resulting in short stature, which is often disproportionate. The underlying mutations are often in the structural genes encoding components of the matrix but may also involve growth factors or cell signalling. In contrast, the
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45

O’Riordan, Stephen MP, and Antoinette Moran. Cystic fibrosis-related diabetes. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780198702948.003.0008.

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This chapter on CFRD reviews the ever-evolving topic and provides up-to-date information on how to diagnose and manage cystic fibrosis-related diabetes CFRD in the acute and chronic setting. The treatments necessary to treat and prolong life in CF, including their unique dietary requirements, must always be followed as a first priority, with diabetes care adjusted accordingly. Early intervention with insulin has been shown to reverse clinical deterioration, even in those with mild diabetes. Newly emerging treatments for CF which have the potential to restore defective chloride channels may hav
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46

Alihodžić, Sead, Erik Asplund, Ingrid Bicu, and Peter Wolf. Electoral Risks: Guide on Internal Risk Factors. The International Institute for Democracy and Electoral Assistance (International IDEA), 2024. http://dx.doi.org/10.31752/idea.2024.40.

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The organization of elections is a complex undertaking for any society. It requires the broadest social mobilization and implementation of various electoral activities, while complying with strict procedures and deadlines. Therefore, many things can—and often do—go wrong due to deficient laws, logistical hurdles, technical and human errors, or unethical actions taken by key electoral actors, to mention a few. When risks materialize, they can generate stresses, shocks or crises that can undermine the integrity of the electoral process. This Guide outlines key process-related (endogenous or inte
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47

Stanworth, Simon, and Stuart McKechnie. Pathophysiology of disordered coagulation. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0269.

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Imbalances in the regulation of haemostasis may manifest as bleeding (depletion of pro-coagulant factors) or thrombosis (deficiency of anti-coagulants). Disordered haemostasis is common in critically-ill patients and may result from infection, trauma, haemorrhage, inflammation, organ dysfunction (notably renal and liver dysfunction), or drug therapy. Complex patterns of coagulopathy where both bleeding and prothrombotic tendencies co-exist are well recognized in critical illness. The limitations of standard laboratory coagulation tests to predict bleeding risk, including activated partial thro
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48

Alihodžić, Sead, Erik Asplund, Ingrid Bicu, and Julia Thalin. Electoral Risks: Guide on External Risk Factors. 3rd ed. The International Institute for Democracy and Electoral Assistance (International IDEA), 2024. http://dx.doi.org/10.31752/idea.2024.39.

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The organization of elections is a complex undertaking for any society. It requires the broadest social mobilization and implementation of various electoral activities, while complying with strict procedures and deadlines. Therefore, many things can—and often do—go wrong due to deficient laws, logistical hurdles, technical and human errors, or unethical actions taken by key electoral actors, to mention a few. When risks materialize, they can generate stresses, shocks or crises that can undermine the integrity of the electoral process. The Guide outlines key context-related (exogenous or extern
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49

Bunch, Chris. Haemolytic anaemia. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0280.

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Haemolytic anaemias occur when the rate of red-cell breakdown is increased and exceeds the marrow’s capacity to generate new cells. Increased red-cell destruction, or haemolysis, may reflect a broad range of disorders. Some involve intrinsic defects in the red cell itself; in others, the red cells are normal but are subjected to external factors which lead to premature destruction. Many of the intrinsic defects are due to inherited disorders affecting the red-cell membrane, its enzymes, or haemoglobin. The marrow can normally compensate for moderate haemolysis by increasing red-cell production
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50

Albright, Robert C. Acid-Base and Electrolyte Disorders. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199755691.003.0474.

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The most important principle in understanding disorders of water balance is that sodium balance is determined by the adequacy of the effective circulating volume, while water balance is determined by osmoregulation and the interplay between vasopressin activity, renal concentrating and diluting ability, and thirst. Disorders of sodium balance can be determined only by clinical examination. Orthostatic hypotension implies volume depletion and sodium deficiency. Edema implies volume excess and sodium excess. Potassium is predominantly an intracellular cation. The intracellular balance of potassi
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