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Journal articles on the topic 'Failed DCR'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Gökçek, A., M. A. Argin, and A. K. Altintas. "Comparison of Failed and Successful Dacryocystorhinostomy by Using Computed Tomographic Dacryocystography Findings." European Journal of Ophthalmology 15, no. 5 (2005): 523–29. http://dx.doi.org/10.1177/112067210501500501.

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Purpose To compare the spiral computed tomographic dacryocystography (CT-DCG) findings of failed and successful dacryocystorhinostomies (DCR) and to detect the possible causes of failure before reoperation. Methods Eighteen patients with failed and 15 patients with functional DCR were examined by spiral CT-DCG, a combination of contrast dacryocystography and spiral computed tomography. Radiologists, who were blinded to the clinical status of the patients, measured the diameter of the osteotomy window, evaluated its position relative to the lacrimal sac, and documented any abnormal findings aro

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2

Sreenivas, V., P. Chaitanya, and Manjoo Reddy. "Early bi-canalicular silicone stent intubation in failed DCR with endoscopic visualization: a combined approach." International Journal of Otorhinolaryngology and Head and Neck Surgery 5, no. 3 (2019): 613. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20191619.

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<p class="abstract"><strong>Background:</strong> Chronic dacryosystitis is a common condition affecting the eye and presenting to ENT surgeons and ophthalmologists, and treated with DCR (dacryocystorhinostomy). In few cases there can be recurrence of symptoms following DCR surgery which can be treated with bi-canalicular silicone intubation. The aim of this study is to assess the effectiveness of an early bi-canalicular silicone intubation in patients with failed DCR using endoscopic visualisation.</p><p class="abstract"><strong>Methods:</strong> This

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3

Yu, Bo, Guang-Ming Zhou, Jie-Liang Shi, En-De Wu, and Wen-Can Wu. "Management of chronic dacryocystitis cases after failed external dacryocystorhinostomy using endoscopic technique with a novel lacrimal ostium stent." International Journal of Ophthalmology 15, no. 3 (2022): 413–19. http://dx.doi.org/10.18240/ijo.2022.03.07.

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AIM: To demonstrate the outcomes of endoscopic endonasal dacryocystorhinostomy (En-DCR) with an novel lacrimal ostium stent (LOS) which was performed in patients with recurrent epiphora after failed external dacryocystorhinostomy (Ex-DCR) and analyze the causes of failed Ex-DCR. METHODS: From September 2015 and December 2017, the clinic data of 29 cases suffered from recurrent epiphora after failed Ex-DCR was reviewed. The LOS were implanted into the ostium at the end of the revisional surgery. The causes of failed Ex-DCR were analyzed before revisional surgeries. Outcome of revisional surgeri

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Herzallah, Islam R., Osama A. Marglani, Sumaiya H. Muathen, and Arwa A. Obaid. "Endoscopic and Radiologic Findings in Failed Dacryocystorhinostomy: Teaching Pearls for Success." American Journal of Rhinology & Allergy 33, no. 3 (2018): 247–55. http://dx.doi.org/10.1177/1945892418815044.

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Background Although several studies have commented on causes of dacryocystorhinostomy (DCR) failure, detailed description of anatomical findings in such cases remains insufficient. Objective Our objective was primarily to analyze radiologic, endoscopic, and intraoperative findings in patients presenting with failed DCR and secondarily to assess the outcome of revision endoscopic DCR (endo-DCR) carried out at our institution. Methods Twenty-four failed DCRs presenting to our tertiary care center were retrospectively analyzed. Data collection included patients’ history, diagnostic, and managemen

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5

Ahmed, Mohammed Naveed, Muneeruddin Ahmed S, Mahendra Kumar M, Ramakrishna Ramakrishna, Siva Prasad G, and Boddikuri Sreekanth. "CLINICAL EVALUATION OF FAILED ENDONASAL DCR OPERATIONS AND THEIR MANAGEMENT." Journal of Evolution of Medical and Dental Sciences 3, no. 48 (2014): 11526–32. http://dx.doi.org/10.14260/jemds/2014/3510.

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Letarte, François, Julie Hallet, Sébastien Drolet, et al. "Laparoscopic Emergency Surgery for Diverticular Disease That Failed Medical Treatment." Diseases of the Colon & Rectum 56, no. 12 (2013): 1395–402. http://dx.doi.org/10.1097/dcr.0b013e3182a760b6.

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Lavryk, Olga A., Luca Stocchi, Sherief Shawki, et al. "Redo IPAA After a Failed Pouch In Patients With Crohn’s Disease." Diseases of the Colon & Rectum 63, no. 6 (2020): 823–30. http://dx.doi.org/10.1097/dcr.0000000000001644.

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8

Poonam, Kumari Pinki, and Bhaskar Gyan. "A Hospital-Based Comparative Assessment of the Outcome of Revision External Dacryocystorhinostomy (DCR) With or Without Mitomycin C." International Journal of Pharmaceutical and Clinical Research 15, no. 3 (2023): 811–16. https://doi.org/10.5281/zenodo.12775214.

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<strong>Aim: </strong>The aim of the present study was to compare the outcome of revision external dacryocystorhinostomy (DCR) with or without mitomycin C. <strong>Methods: </strong>This prospective study was conducted on over 50 diagnosed patients with failed external dacryocystorhinostomy who arrived at the Regional Institute of Ophthalmology, IGIMS, Patna, Bihar, India for one year. <strong>Results: </strong>In 50 diagnosed patients with failed external dacryocystorhinostomy Group A underwent revision external dacryocystorhinostomy with Mitomycin–C and Group B

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Remzi, Feza H., Victor W. Fazio, Hasan T. Kirat, James S. Wu, Ian C. Lavery, and Ravi P. Kiran. "Repeat Pouch Surgery by the Abdominal Approach Safely Salvages Failed Ileal Pelvic Pouch." Diseases of the Colon & Rectum 52, no. 2 (2009): 198–204. http://dx.doi.org/10.1007/dcr.0b013e31819ad4b6.

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10

Lian, Lei, Victor W. Fazio, Feza H. Remzi, Bo Shen, David Dietz, and Ravi P. Kiran. "Outcomes for Patients Undergoing Continent Ileostomy After a Failed Ileal Pouch-Anal Anastomosis." Diseases of the Colon & Rectum 52, no. 8 (2009): 1409–14. http://dx.doi.org/10.1007/dcr.0b013e3181ab586b.

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11

Islam, AKM Rafiqul, Khandaker Anowar Hossain, Md Abdur Rashid, and Md Amjad Hossain. "A Study of Conventional Dacryocystorhinostomy Operation without Silicon Tube Intubation in a Secondary Hospital." Faridpur Medical College Journal 10, no. 1 (2016): 20–22. http://dx.doi.org/10.3329/fmcj.v10i1.27919.

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Dacryocystorhinostomy (DCR) is a bypass surgery in which an anastomosis is made between the medial wall of the lacrimal sac & the lateral wall of the nasal mucosa by cutting the intervening bone at the level of middle meatus to restore the flow of tears when the obstruction is beyond the common canaliculus. The only successful treatment of chronic dacryocystitis is DCR. The aim of this study was to evaluate the surgical intervention of conventional external DCR without silicon tube intubation. This prospective study was conducted at General Hospital, Faridpur from July 2012 to June 2014. E

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Aydinli, H. Hande, Eren Esen, Erman Aytac, et al. "Transabdominal Pouch Salvage for Failed Minimally Invasive Versus Open IPAA: A Case-Matched Study." Diseases of the Colon & Rectum 63, no. 8 (2020): 1102–7. http://dx.doi.org/10.1097/dcr.0000000000001609.

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13

Genser, Laurent, Gilles Manceau, Mehdi Karoui, et al. "Postoperative and Long-term Outcomes After Redo Surgery for Failed Colorectal or Coloanal Anastomosis." Diseases of the Colon & Rectum 56, no. 6 (2013): 747–55. http://dx.doi.org/10.1097/dcr.0b013e3182853c44.

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Wong, Mark T. C., Guillaume Meurette, François Rodat, Nicolas Regenet, Vincent Wyart, and Paul-Antoine Lehur. "Outcome and Management of Patients in Whom Sacral Nerve Stimulation for Fecal Incontinence Failed." Diseases of the Colon & Rectum 54, no. 4 (2011): 425–32. http://dx.doi.org/10.1007/dcr.0b013e318200f866.

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15

Jan, Sabhia, Apoorva ., Junaid S. Wani, Raheel Riaz, and Ovais Nazir. "Evaluation of dacryocystorhinostomy failure with computed tomographic dacryocystography." International Journal of Research in Medical Sciences 5, no. 12 (2017): 5197. http://dx.doi.org/10.18203/2320-6012.ijrms20175130.

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Background: The purpose of this study is to evaluate the causes of failure of dacryocystorhinostomy by computed dacryocystography (CT-DCG).Methods: CT-DCG was done in 38 patients of failed DCR of either sex in the age group of 16-60 years, the radiologist blinded to the clinical status of the patient evaluated position and size of bony ostium, soft tissue scarring, bony regrowth, secondary stenosis of canaliculi, synechiae between the ostium and nasal septum and anatomic variations in nasal cavity, turbinates or nasal septum.Results: The most common causes of failure in our study were inapprop

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16

Ukoette Jeremiah Ekah and Chibuzo Emeruwa. "Guaging of key performance indicators for 2G mobile networks in Calabar, Nigeria." World Journal of Advanced Research and Reviews 12, no. 2 (2021): 157–63. http://dx.doi.org/10.30574/wjarr.2021.12.2.0550.

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The increase in the number of mobile subscribers, coupled with the increase in mobile services is enough reason to monitor the QoS of mobile network operators frequently. This work looks into the QoS of network operators in Calabar, Nigeria, taking into consideration some KPIs ((CSSR, DCR, CST, HOSR, and network quality and network coverage). Analysis of data obtained after a benchmarking drive test shows that Globacom network was within NCC performance threshold for all network KPIs monitored. Also, MTN network performed poorly in HOSR but met the minimum benchmark in other network KPIs. Airt

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Ukoette, Jeremiah Ekah, and Emeruwa Chibuzo. "Guaging of key performance indicators for 2G mobile networks in Calabar, Nigeria." World Journal of Advanced Research and Reviews 12, no. 2 (2021): 157–63. https://doi.org/10.5281/zenodo.5716638.

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The increase in the number of mobile subscribers, coupled with the increase in mobile services is enough reason to monitor the QoS of mobile network operators frequently. This work looks into the QoS of network operators in Calabar, Nigeria, taking into consideration some KPIs ((CSSR, DCR, CST, HOSR, and network quality and network coverage). Analysis of data obtained after a benchmarking drive test shows that Globacom network was within NCC performance threshold for all network KPIs monitored. Also, MTN network performed poorly in HOSR but met the minimum benchmark in other network KPIs. Airt

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18

Geetha, Abinish Dyneese, Rajavarma Paquirissamy, Aswin John, Kalaivani Sivakumar, and Lokeshvaran Deivendran. "A case report on the success of endoscopic dacryocystorhinostomy following unsuccessful external dacryocystorhinostomy in a patient with nasolacrimal duct obstruction." IP Journal of Otorhinolaryngology and Allied Science 7, no. 4 (2024): 83–87. https://doi.org/10.18231/j.ijoas.2024.021.

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Endoscopic dacryocystorhinostomy (DCR) is a surgical remedy for nasolacrimal duct obstructions (NLDO), addressing symptoms like excessive tear secretion and swelling. This article presents an observational case report of a 60-year-old female with persistent tear secretion and a non-healing ulcer below the left medial canthus at the previously operated external DCR site, managed initially with antibiotics and secondarily with closure of the external wound. Endoscopic DCR was subsequently performed under local anesthesia, effectively resolving symptoms and facilitating recovery. Advantages of en

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19

Kahn, D., R. D. Williams, M. K. Haseman, N. L. Reed, S. J. Miller, and J. Gerstbrein. "Radioimmunoscintigraphy with In-111-labeled capromab pendetide predicts prostate cancer response to salvage radiotherapy after failed radical prostatectomy." Journal of Clinical Oncology 16, no. 1 (1998): 284–89. http://dx.doi.org/10.1200/jco.1998.16.1.284.

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PURPOSE We investigated the ability of In-111-capromab pendetide to separate patients who have failed radical prostatectomy into categories of those who would versus those who would not respond to salvage radiotherapy. METHODS Prostate-specific antigen (PSA) levels in 32 men with prostate cancer who had failed radical prostatectomy and had undergone a whole-body In-111-capromab pendetide scan were followed-up for 13 months (median) after salvage radiotherapy to the pelvis. A logistic regression model was used to determine whether the scan findings, as well as other clinical variables, were ass

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Dantuluri, R. K. L. N. Raju. "Endoscopic dacryocystorhinostomy for nasolacrimal duct obstruction: an assessment of post-operative outcomes at a tertiary health care centre." International Journal of Research in Medical Sciences 9, no. 12 (2021): 3586. http://dx.doi.org/10.18203/2320-6012.ijrms20214466.

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Background: Endoscopic dacryocystorhinostomy (Endo DCR) is a well-established surgical treatment for nasolacrimal duct obstruction (NLDO) cases. Advances in surgical technique and a better understanding of the anatomy have resulted in improvement of the success rate. The objective of this study is to assess the factors responsible for the recurrence of nasolacrimal system obstruction by evaluating the post-operative outcomes of Endo DCR at a tertiary health care centre.Methods: A retrospective study was conducted in the department of ENT, GVP IHC and MT, Visakhapatnam – Andhra Pradesh on 52 pa

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21

Aytac, Erman, David W. Dietz, Jean Ashburn, and Feza H. Remzi. "Is Conversion of a Failed IPAA to a Continent Ileostomy a Risk Factor for Long-term Failure?" Diseases of the Colon & Rectum 62, no. 2 (2019): 217–22. http://dx.doi.org/10.1097/dcr.0000000000001277.

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22

Challine, Alexandre, Jeremie H. Lefèvre, Ben Creavin, et al. "Can a Local Drainage Salvage a Failed Colorectal or Coloanal Anastomosis? A Prospective Cohort of 54 Patients." Diseases of the Colon & Rectum 63, no. 1 (2020): 93–100. http://dx.doi.org/10.1097/dcr.0000000000001516.

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23

Mandal, Salil Kumar, Purban Ganguly, Nazibul Hasan Mallick, Pankaj Shil, Oishik Sarkar, and Anwesha Maitra. "Surgical Outcome of Intubation Dacryocystorhinostomy with Double Threaded Silk Sutures in Failed DCR." Journal of Evidence Based Medicine and Healthcare 7, no. 37 (2020): 2068–73. http://dx.doi.org/10.18410/jebmh/2020/429.

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24

Sahu, Sumit Kumar. "A Comparative Study of Safety and Efficacy of Mitomycin-C (0.08 mg) and Bevacizumab (7.5 mg) in Cases of External Dacryocystorhinostomy." Delhi Journal of Ophthalmology 33, no. 2 (2023): 97–100. https://doi.org/10.4103/dljo.dljo_95_23.

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Purpose: The purpose of this study was to evaluate the safety and efficacy of mitomycin-C (MMC) (0.08 mg) and bevacizumab (7.5 mg) in external dacryocystorhinostomy (DCR) and compare their outcomes. Methods: This was a prospective, randomized, comparative study in which a total of 20 patients were enrolled, 10 patients in Group A (MMC-assisted DCR) and 10 patients in Group B (bevacizumab-assisted DCR). All the patients were operated by a single surgeon. After fashioning of the nasal mucosal flap, in Group A, circumostial intramucosal injection of 0.02% MMC (0.08 mg in 0.4 mL) was injected equa

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Cancela, Héctor, Franco Robledo, Pablo Romero, and Pablo Sartor. "Diameter constrained reliability of ladders and Spanish fans." Yugoslav Journal of Operations Research 26, no. 1 (2016): 17–32. http://dx.doi.org/10.2298/yjor140721004c.

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We are given a graph G = (V, E), terminal set K ? V and diameter d > 0. Links fail stochastically and independently with known probabilities. The diameter-constrained reliability (DCR for short), is the probability that the K-diameter is not greater than d in the subgraph induced by non-failed links. The contributions of this paper are two-fold. First, the computational complexity of DCR-subproblems is discussed in terms of the number of terminals k = jKj and diameter d. Here, we prove that when d > 2 the problem is NP-Hard when K = V. Second, we compute the DCR efficiently for Ladders a

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Gou, Wenjun, Heng Li, Xu Yang, et al. "Influence of Indwelling Lacrimal Drainage Tube on the Curative Effect of Endonasal Endoscopic Dacryocystorhinostomy." Journal of Biomaterials and Tissue Engineering 11, no. 6 (2021): 1201–5. http://dx.doi.org/10.1166/jbt.2021.2718.

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Endonasal endoscopic dacryocystorhinostomy (EES-DCR) has gradually become the main surgical method for treating chronic dacryocystitis. Whether the placement of the lacrimal drainage tube during the operation can improve the operation’s success rate is an issue. This study observes the effect of an indwelling lacrimal drainage tube on the curative effect of EES-DCR in patients with chronic dacryocystitis. The cure rate of the Lacrimal duct drainage tube non-indwelling group A was 93.8% (46/49). The 3 cases failed because of the nasal cavity’s inflammation, which resulted in the adhesion of the

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27

Books, Charles N., James B. Talmage, and J. Mark Melhorn. "Rating Distal Clavicle Resection." Guides Newsletter 17, no. 1 (2012): 13–16. http://dx.doi.org/10.1001/amaguidesnewsletters.2012.janfeb02.

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Abstract Indications for excision of the distal clavicle include symptomatic degenerative arthritis of the acromioclavicular joint, impingement syndrome, and osteolysis of the distal clavicle if nonoperative treatment has failed. Distal clavicular resection (DCR), one could argue, is by definition an impairment because of the loss of a portion of a body part, the clavicle. Yet a competently performed and uncomplicated DCR generally results in improved function, not loss of use. DCR was first mentioned in the AMA Guides to the Evaluation of Permanent Impairment (AMA Guides), Fourth Edition, whi

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HUSSAIN, M., S. AKHTAR, M. A. CHOUDHRY, and N. DIN. "Close Intubation of Lacrimal Drainage System in Children." Annals of King Edward Medical University 4, no. 3 (2020): 68–70. https://doi.org/10.21649/akemu.v4i3.3954.

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A retrospective study was conducted at Eye Deptt. Lahore General Hospital Lahore for epiphora in children. We performed closed intubation in 19 children where syringing and probing had failed twice at least. All the patients were done under General Anesthesia. In three patients we had collaboration of ENR surgeon. We had success rate of 84.2%. Our procedure failed in three patients, we had to do dacryocystorhinostomy (DCR) in one 8 years old patient. The rest of the two patient had no relief of epiphora and discharge.

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Jeon, Hye Min, Dong Seob Ahn, and Joo Heon Roh. "Surgical Outcomes of Endonasal Revision Surgery for Failed DCR According to Number of Silicone Tubes." Journal of the Korean Ophthalmological Society 56, no. 5 (2015): 651. http://dx.doi.org/10.3341/jkos.2015.56.5.651.

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Khan, Md Anwar Hossain, AHM Zahirul Islam Biswas, and Md Mosharraf Hossain. "Outcome of External Dacryocysto-Rhinostomy (DCR) Operation Without Silicone Tube Intubation." Anwer Khan Modern Medical College Journal 9, no. 2 (2018): 121–23. http://dx.doi.org/10.3329/akmmcj.v9i2.39207.

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Background: Dacryocysto-rhinostomy (DCR) is a bypass surgery in which an anastomosis is made between the medial wall of the lacrimal sac & the lateral wall of the nasal mucosa by cutting the intervening bone at the level of middle meatus to restore the flow of tears when the obstruction is beyond the common canaliculus. The aim of this study was to evaluate the surgical intervention of conventional external DCR without silicon tube intubation.Methods: This study was conducted at Jahurul Islam Medical College Hospital, Kishoregonj, from July 2016 to January 2018. Fifty cases with chronic da

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Bismuth, Yaniv, Joris Beckers, Floris van Rooij, Mo Saffarini, and Arnaud Godenèche. "Outcomes of Secondary Arthroscopic Distal Clavicle Resection for Shoulders With Symptomatic Acromioclavicular Joint Arthropathy After Isolated Rotator Cuff Repair With Complete Tendon Healing." Orthopaedic Journal of Sports Medicine 11, no. 4 (2023): 232596712311631. http://dx.doi.org/10.1177/23259671231163143.

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Background: Recent meta-analyses have advised against distal clavicle resection (DCR) as an adjuvant procedure during rotator cuff repair (RCR), whether performed routinely or in shoulders diagnosed with symptomatic acromioclavicular joint (ACJ) arthropathy. However, the efficacy of DCR as a secondary procedure in patients with persistent pain attributed to symptomatic ACJ arthropathy remains unknown. Purpose: To evaluate outcomes of secondary DCR in patients with failed nonoperative treatment of symptomatic ACJ arthropathy after isolated RCR with complete tendon healing. Study Design: Case se

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32

Alnawaiseh, M., N. Mihailovic, A. C. Wieneke, et al. "Long-Term Outcomes of External Dacryocystorhinostomy in the Age of Transcanalicular Microendoscopic Techniques." Journal of Ophthalmology 2016 (2016): 1–4. http://dx.doi.org/10.1155/2016/5918457.

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Purpose.This study aimed to evaluate long-term results of external dacryocystorhinostomy (DCR) at a tertiary eye care center specializing in lacrimal duct surgery in Germany.Methods.The medical records of 1010 patients with acquired nasolacrimal duct obstruction (NLDO), who had undergone lacrimal duct surgery at a tertiary eye care center, were reviewed. Only adult patients who had undergone external DCR were included. The evaluation included the following parameters: age, gender, duration of symptoms, patient satisfaction, previous dacryocystitis, complication rates, and surgical outcome.Resu

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Lu, Shun, Zhen Zhou, Zi-Ming Li, et al. "Abstract CT008: First-in-human study of SYS6010, a novel EGFR targeting antibody drug conjugate (ADC) for patients with advanced solid tumors." Cancer Research 85, no. 8_Supplement_2 (2025): CT008. https://doi.org/10.1158/1538-7445.am2025-ct008.

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Abstract Background: SYS6010 is a novel ADC comprising of an anti-epidermal growth factor receptor (EGFR) humanized IgG1 monoclonal antibody conjugated to topoisomerase I inhibitor JS-1 via a cleavable glycine̶̶-glycine-phenylalanine-glycine tetrapeptide linker. Methods: This multicenter, open-label, phase 1 study evaluated the safety, tolerability and preliminary efficacy of SYS6010 in patients with advanced solid tumors who had failed or were intolerant to standard treatment. The study consisted of two parts, dose escalation, PK expansion (part 1) and dose expansion (part 2), part 1 used a 3

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Shen, Jie, Rutian Li, Jing Yan, et al. "A phase II study to evaluate the safety and efficacy of radiotherapy combined with irinotecan liposome followed by camrelizumab and apatinib for advanced solid tumors that failed standard treatments." Journal of Clinical Oncology 40, no. 16_suppl (2022): 2567. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.2567.

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2567 Background: Liposomes deliver the drug to tumors based on enhanced permeability and retention (EPR) effects. Radiotherapy further prompts the distribution of liposomal drugs to tumor sites receiving radiotherapy by altering the tumor microenvironment. In addition, radiotherapy might enhance systemic antitumoral responses to immunotherapy. Herein, we aimed to explore safety and efficacy of radiotherapy in combination with irinotecan liposome, immunotherapy, and antiangiogenic therapy in advanced solid tumors patients (pts) that failed standard treatments. Methods: Anopen single-arm, multi-

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Subudhi, Praveen. "External Repeat Dacryocystorhinostomy with Modified Silicone Intubation for Failed DCR: Analysis of Efficacy and Patient Tolerability." Delhi Journal of Ophthalmology 25, no. 4 (2015): 242–45. http://dx.doi.org/10.7869/djo.116.

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Khan, Imtiaz Ahmed, Naseeruddin Mujahid, and Nabeel Nabeel. "A Comparative Study of Dacryocystorhinostomy with or without Stent in a Tertiary Teaching Hospital of Telangana." Journal of Evidence Based Medicine and Healthcare 8, no. 20 (2021): 1532–37. http://dx.doi.org/10.18410/jebmh/2021/290.

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BACKGROUND Epiphora is a common annoying symptom, embarrassing the patient both socially and functionally and may even endanger the eye. Chronic Dacryocystitis is the most common cause of epiphora which arises from nasolacrimal duct occlusion. Dacryocystorhinostomy (DCR) is the procedure of choice in the management of Dacryocystitis. We wanted to study the final outcome following endonasal DCR for chronic dacryocystitis with or without using silicon stent, evaluate the causes of persistence of epiphora in patients with or without the use of lacrimal stents and identify the methods of overcomin

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Hsu, Chia-Chen, Lung-Chi Lee, Bo-I. Kuo, Che-Jui Lee, and Fang-Yu Liu. "Surgical and Anatomic Consideration in Endoscopic Dacryocystorhinostomy of a Patient with Damaged Sinonasal Anatomy Post–Caldwell-Luc Surgery: A Case Report." Medicina 58, no. 1 (2022): 78. http://dx.doi.org/10.3390/medicina58010078.

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Background: The Caldwell-Luc (CL) procedure, an outdated operative procedure that is used to treat inflammatory sinus diseases, is rarely performed presently. However, physicians may encounter patients with a history of CL surgery who develop considerable postoperative changes that may lead to diagnostic confusion in imaging evaluation; increase the difficulty of future surgery, such as sinonasal surgery; and increase the incidence of future intraoperative complications. Case summary: A 67-year-old man with a surgical history of chronic sinusitis reported epiphora of the left eye for five year

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Yang, Guang, and Hai Wang. "Optimal Pressure Sensor Deployment for Leak Identification in Water Distribution Networks." Sensors 23, no. 12 (2023): 5691. http://dx.doi.org/10.3390/s23125691.

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Pipe leakage is an inevitable phenomenon in water distribution networks (WDNs), leading to energy waste and economic damage. Leakage events can be reflected quickly by pressure values, and the deployment of pressure sensors is significant for minimizing the leakage ratio of WDNs. Concerning the restriction of realistic factors, including project budgets, available sensor installation locations, and sensor fault uncertainties, a practical methodology is proposed in this paper to optimize pressure sensor deployment for leak identification in terms of these realistic issues. Two indexes are utili

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Ul Kadir, Syeed Mehbub, Farhana Afrin Nipa, Sadia Sultana, Riffat Rashid, and Farzana Afzal. "The outcome of revision external dacryocystorhinostomy with or without mitomycin C: A single-center experience." Indian Journal of Clinical and Experimental Ophthalmology 8, no. 3 (2022): 320–24. http://dx.doi.org/10.18231/j.ijceo.2022.066.

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To compare the outcome of revision external dacryocystorhinostomy (DCR) with or without mitomycin C. This Quasi prospective study was conducted over 30 diagnosed patients with failed external dacryocystorhinostomy came to the Oculoplasty clinic at Ispahani Islamia Eye Institute and Hospital from July 2019 to June 2020. Maximum of 40.0% of the patients were 41–50 age group in Group A (Mitomycin C) and 40.0% in 41-50 age group in Group B (without Mitomycin C). There were 7(46.7%) males, and 54-58 8(53.3%) females in Group A, 6(40.0%) male and 9(60.0%) female in Group B. 18(60%) patients underwen

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Xu, Rui-hua, Lin Shen, Keming Wang, et al. "A randomized, double-blind, parallel-group, placebo-controlled, multicenter, phase II clinical study of famitinib in the treatment of advanced metastatic colorectal cancer." Journal of Clinical Oncology 33, no. 3_suppl (2015): 513. http://dx.doi.org/10.1200/jco.2015.33.3_suppl.513.

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513 Background: Colorectal cancer (CRC) is the third most frequently diagnosed cancer and is the fifth leading cause of cancer death in China. No standard care is available for patients with advanced CRC who failed the second-line treatment. Famitinib is a small-molecular, multi-target receptor tyrosine kinase inhibitor which primarily acts against angiogenesis. This phase II study was designed to evaluate the efficacy and safety of famitinib in the treatment of advanced colorectal cancer. Methods: This is a multi-center, randomized, double-blind, placebo-controlled, phase II clinical study (C

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Al-Arayedh, Mohamed, Muneera Al-Rowaila, and Heba Al-Reefy. "Foreign body in the right nasal cavity secondary to embedded dacryocystorhinostomy tube." International Journal of Otorhinolaryngology and Head and Neck Surgery 9, no. 3 (2023): 229–31. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20230412.

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A 39-year-old male patient was presented with foreign body sensation eight months post unilateral dacryocystorhinostomy (DCR) tube procedure in his right lower Punctum. On examination, the (silicon-based stent) was patent on the right orbital Punctum. However, the nasal element of the DCR tube was undetected during examination using the nasal speculum. endoscopic examination of the nasal cavity failed to reveal the nasal portion of the tube. None of the approaches performed were successful to detect the exact site of the stent. Therefore, the patient was transferred to the theatre to remove th

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Mansour, Hosam Othman, Riad Elzaher Hassan, Ehab Tharwat, et al. "Comparing the success rate of external dacryocystorhinostomy with anterior flap versus flap excision in managing chronic dacryocystitis." Medical hypothesis discovery and innovation in ophthalmology 12, no. 1 (2023): 1–8. http://dx.doi.org/10.51329/mehdiophthal1464.

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Background: Nasolacrimal duct obstruction (NLDO) is characterized by epiphora and recurrent episodes of acute dacryocystitis. Despite the temporary effect of antibiotics in the acute phase, it is primarily managed by dacryocystorhinostomy (DCR). There is a new modification of external DCR that is performed without either anterior or posterior flaps. This study aimed to compare the outcomes of flapless and single-flap external DCR in adult patients with chronic symptomatic dacryocystitis secondary to NLDO. Methods: In this retrospective, non-randomized, interventional, comparative study o

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Zhou, Juying, Chao Xu, Lu Zhang, and Chenying Ma. "Efficacy and safety of penpulimab-containing regimens for advanced malignant solid tumors that have failed immunotherapy: A real-world study." Journal of Clinical Oncology 41, no. 16_suppl (2023): e14700-e14700. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e14700.

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e14700 Background: Immuno-checkpoint inhibitors (ICI) have shown good anti-tumor efficacy and survival benefits in a variety of solid tumors, such lung cancer, gastric cancer, esophageal cancer, head and neck squamous cell carcinoma (HNSCC). ICI have rewritten the guidelines for multiple tumor types. However, there are still a large number of patients who are ineffective or initially effective after use ICI, and subsequently develop ICI resistance. For these patients, how we choose further treatment is currently uncertain clinically. Some studies suggest that even if the treatment of PD - (L)

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Mu, Fengchun, Bingjie Fan, Butuo Li, et al. "Albumin-bound paclitaxel plus PD-1/PD-L1 inhibitor versus second-line chemotherapy for patients with recurrent small cell lung cancer." Journal of Clinical Oncology 39, no. 15_suppl (2021): e20591-e20591. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e20591.

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e20591 Background: The main aim of this study was to evaluate the efficiency of albumin-bound paclitaxel (nab-PTX) plus PD-1/PD-L1 inhibitor versus second-line chemotherapy in small cell lung cancer (SCLC) patients who have failure to the first-line standard treatment. Methods: We retrospectively collected patients’ data from medical records between January 2015 to July 2020 in Shandong Cancer Hospital and Institute. Consecutive 42 patients who were treated with nab-PTX plus PD-1/PD-L1 inhibitor were enrolled and compared with, 126 patients who received second-line chemotherapy (1:3 matched wi

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Yao, Weitao, Jiaqiang Wang, Peng Zhang, et al. "Efficacy and safety of anlotinib hydrochloride in the treatment of advanced bone and soft tissue sarcoma after failure of first-line chemotherapy." Journal of Clinical Oncology 39, no. 15_suppl (2021): e23504-e23504. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e23504.

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e23504 Background: There were limit treatments for bone and soft tissue sarcomas that have failed chemotherapy. Anlotinib hydrochloride is a multi-targeted receptor of tyrosine kinase inhibitors (TKI), which has shown therapeutic effects on soft tissue sarcoma. Methods: This is a single-arm, prospective, single-center clinical study. The included criteria were patients with pathological diagnose of bone and soft tissue sarcoma, at least one measurable lesion (criteria of RECIST 1.1), failed of more than one line therapy (except for sarcoma subtypes insensitive to chemotherapy), with the normal

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Zhou, Tong, Xiaoyue Zhou, Peng Li, et al. "A retrospective study of low-dose apatinib combined with S-1 in patients with advanced non-small cell lung cancer." Journal of Clinical Oncology 37, no. 15_suppl (2019): e20666-e20666. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e20666.

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e20666 Background: Currently regimen for advanced non-small cell lung cancer (NSCLC) failing from standard treatment is deficient. This retrospective study aimed to assess the efficacy and safety of low-dose apatinib in combination with S-1 therapy in this NSCLC setting. Methods: In this retrospective study, advanced NSCLC patients who failed from standard treatment in Changzhou Cancer Hospital of Soochow University were screened for eligibility. Progression-free survival (PFS) was set as the primary endpoint. Overall response rate (ORR), disease control rate (DCR), Overall survival (OS) and s

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Weitao, Yao, Jiaqiang Wang, Peng Zhang, et al. "Preliminary evaluate the safety and efficacy of anlotinib in advanced sarcoma patients in multi-line therapy." Journal of Clinical Oncology 38, no. 15_suppl (2020): 11526. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.11526.

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11526 Background: Patients with advanced bone and soft tissue sarcoma are mostly treated with chemotherapy, but the effect is poor. Anlotinib hydrochloride is a multi-targeted receptor of tyrosine kinase inhibitors (TKI), which has demonstrated therapeutic effects on a variety of sarcoma subtypes, and is approved for the treatment of advanced soft tissue sarcomas in China. Methods: This is a single-arm, prospective, single-center clinical study. The included criteria were patients with pathological diagnose of bone and soft tissue sarcoma, at least one measurable lesion (according to RECIST 1.

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Wang, Feng, Boris Gorsh, Maral DerSarkissian, et al. "Treatment Patterns and Outcomes of Patients with Double-Class Refractory or Triple-Class Refractory Multiple Myeloma: A Retrospective US Electronic Health Record Database Study." Blood 138, Supplement 1 (2021): 2705. http://dx.doi.org/10.1182/blood-2021-152301.

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Abstract Introduction: Patients with relapsed/refractory multiple myeloma (RRMM) resistant to multiple drug classes remain a high unmet need population, despite advances in MM patient care. The objective of this study was to assess real-world treatment patterns and outcomes in patients with RRMM who had failed multiple prior lines of therapy (LOT) and were refractory to multiple drug classes to identify gaps in their treatment pathways. Methods: This longitudinal retrospective cohort study utilized the COTA de-identified real-world database derived from US electronic health records of partnere

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Gu, Xiaoqiang. "Fruquintinib in patients with metastatic colorectal cancer failed in previously bevacizumab-based therapy: A monocentric retrospective study." Journal of Clinical Oncology 39, no. 15_suppl (2021): e15555-e15555. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e15555.

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e15555 Background: Fruquintinib, a vascular endothelial growth factor receptor (VEGFR) inhibitor, is a new targeting anti-cancer agent for refractory metastatic colorectal cancer (mCRC). Promising antitumor effect of fruquintinib monotherapy was verified in a phase III FRESCO randomized study of mCRC patients, and only 30% patients were prior bevacizumab-treated. However, comprehensive effect evaluation of fruquintinib in mCRC patients who have previously failed in bevacizumab therapy were scarce. Methods: Forty patients with metastatic CRC who had previously failed at least 2 lines of standar

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Herzallah, Islam R., Osama A. Marglani, Ameen Z. Alherabi, Nuha S. Faraj, and Deemah H. Bukhari. "Bilateral Simultaneous Endoscopic Dacryocystorhinostomy: Outcome and Impact on the Quality of Life of the Patients." International Archives of Otorhinolaryngology 23, no. 02 (2019): 191–95. http://dx.doi.org/10.1055/s-0038-1675394.

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Introduction Bilateral simultaneous endoscopic dacryocystorhinostomy (endo-DCR) has received little attention in the literature, thus many surgeons continue to address bilateral nasolacrimal duct obstruction at two stages, rather than in the same setting. Objective To evaluate the feasibility and the outcome of simultaneous bilateral Endo-DCR and its impact on the quality of life of the patients. Methods We have conducted a retrospective analysis of patients who underwent bilateral simultaneous endo-DCR between March 2013 and February 2017 at our tertiary care institution. The reviewed data in

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