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Journal articles on the topic 'Failles normales'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 May 2024

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1

Ngindu Buabua, David. "Rift Upemba et tectonique." Revue Congolaise des Sciences & Technologies 2, no. 2 (2023): 289–95. http://dx.doi.org/10.59228/rcst.023.v2.i2.31.

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Dans ce travail nous allons examiner l’évolution du Rift Upemba par rapport à la tectonique de la région et conclure sur les alignements des failles dans le Rift. Les méthodes utilisées pour cette étude comprennent la télédétection et le traitement par Système d’Information Géographique, grâce au logiciel ArcGIS 10.8. Comme résultats, le Rift Upemba, par rapport à la tectonique de la région, n’est pas constitué d’une seule faille en segment de droite mais de deux failles normales composées situées de part et d’autre du Rift dans la dépression délimitée par des lacs. D’où, le Rift Upemba est co

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Ngindu Buabua, David. "Rift Upemba et tectonique." Revue Congolaise des Sciences & Technologies 02, no. 02 (2023): 289–95. http://dx.doi.org/10.59228/rcst.023.v2.i1.31.

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Dans ce travail nous allons examiner l’évolution du Rift Upemba par rapport à la tectonique de la région et conclure sur les alignements des failles dans le Rift. Les méthodes utilisées pour cette étude comprennent la télédétection et le traitement par Système d’Information Géographique, grâce au logiciel ArcGIS 10.8. Comme résultats, le Rift Upemba, par rapport à la tectonique de la région, n’est pas constitué d’une seule faille en segment de droite mais de deux failles normales composées situées de part et d’autre du Rift dans la dépression délimitée par des lacs. D’où, le Rift Upemba est co

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Meyer, B., J. P. Avouac, P. Tapponnier, and M. Meghraoui. "Mesures topographiques sur le segment SW de la zone faillee d'El Asnam et interpretation mecanique des relations entre failles inverses et normales." Bulletin de la Société Géologique de France VI, no. 3 (1990): 447–56. http://dx.doi.org/10.2113/gssgfbull.vi.3.447.

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Hervouët, Yves, Nicolas Espurt, and Damien Dhont. "Failles normales Paléocène à Lutétien en zone sud-pyrénéenne (Aragon, Espagne) et flexuration de la plaque ibérique." Comptes Rendus Geoscience 337, no. 3 (2005): 385–92. http://dx.doi.org/10.1016/j.crte.2004.11.001.

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Graveleau, Fabien, Frank Chanier, Francis Meilliez, Jean-Yves Reynaud, and Geoffray Musial. "Observation de la surface de transgression du tuffeau thanétien sur la craie coniacienne au niveau du flanc nord de l'anticlinal du Mélantois (Nord)." Annales de la Société géologique du Nord - (2e Série), Tome 28, no. 28 (December 1, 2021): 99–110. http://dx.doi.org/10.54563/asgn.321.

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Le suivi régulier d’un chantier de terrassement localisé à la limite des communes de Lezennes et de Villeneuve d’Ascq, au cœur de la Métropole de Lille (59, Nord), a permis d’observer et d’analyser en détail le contact géologique entre le « tuffeau » du Thanétien et la craie du Coniacien. Cette surface de contact apparaît remarquablement nette et plane, sub-horizontale et faiblement déformée. Quelques failles normales (N100-110) et décrochantes (N-S) la fracturent avec des rejets verticaux décimétriques à métriques. Cette surface est marquée par la présence d’un impressionnant réseau de terrie

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Moulouel, Hakim, Luca Micarelli, Isabelle Moretti, and Djamel Machane. "Fracturation des carbonates dans la zone de faille normale active d’Aigion (Grèce) à partir des carottes du puits: conséquences sur les propriétés de transfert de fluides." Bulletin de la Société Géologique de France 186, no. 6 (2015): 387–97. http://dx.doi.org/10.2113/gssgfbull.186.6.387.

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Abstract La faille d’Aigion appartient à un système de failles normales à pendage nord affectant la bordure sud du golfe de Corinthe, témoin d’une extension active d’échelle régionale caractérisant la région égéenne. Les carottes du forage AIG-10, qui a traversé cette faille, montrent la présence d’une zone endommagée et d’une gouge. Ce travail présente une analyse des lames minces faites à partir de ces carottes. Il confirme la zonation en termes de fracturation à l’approche de la faille. Loin de cette dernière, la fracturation héritée de la phase compressive de l’orogenèse hellénique est dom

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Ferrière, Jacky, and Frank Chanier. "La marge Ouest-Maliaque de la Téthys (Hellénides) : une marge en hyper-extension, pauvre en magma." Annales de la Société géologique du Nord - (2e Série), Tome 28, no. 28 (December 1, 2021): 39–56. http://dx.doi.org/10.54563/asgn.288.

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La reconstitution des marges passives anciennes à partir de l’étude d’affleurements à terre se heurte au problème de la déformation des séries issues de la marge, en raison de leur mise en place tectonique sur les domaines continentaux. Dans le massif de l’Othrys, en Grèce, les témoins d’une marge téthysienne (Océan Maliaque) sont correctement préservés au sein de nappes syn-obduction du Jurassique. Dans ce massif, ces nappes sont nombreuses : 3 nappes ophiolitiques et 6 nappes issues de la marge. L’empilement des nappes est régulier : les nappes possédant des séries de forte profondeur (série

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Ferrière, Jacky, and Frank Chanier. "Analysis of an obduction process: the example of the Tethyan Maliac Ocean (Hellenides)." Annales de la Société Géologique du Nord, no. 27 (December 2, 2020): 37–54. http://dx.doi.org/10.54563/asgn.254.

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L’obduction, charriage de la lithosphère océanique sur la croûte continentale, à l’origine des ophiolites, a été défini suite à la révolution de la tectonique des plaques. Dans un premier temps, les analyses ont surtout porté sur la pétrographie et la géochimie des ensembles ophiolitiques (par ex. Vourinos en Grèce, Troodos à Chypre, nappe du Semail en Oman). Notre étude concerne principalement un secteur des Hellénides, le massif de l’Othrys, où l’on peut observer un système ophiolitique complet représenté par un empilement de nappes mises en place pendant l’obduction de l’Océan téthysien Mal

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Schoonmaker, Adam, William S. F. Kidd, Stephen E. DeLong, and John F. Bender. "Lawrence Head Volcanics and Dunnage Mélange, Newfoundland Appalachians: Origin by Ordovician Ridge Subduction or in Back-Arc Rift?" Geoscience Canada 41, no. 4 (2014): 523. http://dx.doi.org/10.12789/geocanj.2014.41.053.

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This paper reviews the geological setting and reports new geochemical trace element data from the Ordovician Lawrence Head Volcanics (LHV) and the underlying gabbro sills in the Exploits Group. In combination with existing published analyses and ages of these rocks, the volcanic rocks and sills are indistinguishable in composition and age, and the data are consistent with the hypothesis that they represent the same (mostly E-MORB composition) magmatic event in the early–mid Darriwilian (~465 ± 2 Ma). The LHV and their enclosing strata show regional evidence for: 1) upward decline of volume and

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Victor, Jonathan D., Mary M. Conte, Leslie Burton, and Ruth D. Nass. "Visual evoked potentials in dyslexics and normals: Failure to find a difference in transient or steady-state responses." Visual Neuroscience 10, no. 5 (1993): 939–46. http://dx.doi.org/10.1017/s0952523800006155.

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AbstractWe measured transient and steady-state checkerboard contrast-reversal visual evoked potentials (VEPs) in ten dyslexics, five patient controls, and 11 normals over a range of contrasts and luminances. Latency, amplitude, and phase measurements failed to distinguish the responses of dyslexics from those of normals or patient controls. Decreases in luminance or contrast resulted in an increased latency of the transient VEP in all groups, but these changes also did not distinguish the responses of dyslexics from those of the controls. Response variability was similar in dyslexics and norma

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Fioretto, P., R. Trevisan, A. Valerio, et al. "Impaired renal response to a meat meal in insulin-dependent diabetes: role of glucagon and prostaglandins." American Journal of Physiology-Renal Physiology 258, no. 3 (1990): F675—F683. http://dx.doi.org/10.1152/ajprenal.1990.258.3.f675.

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The renal response to 100 g/1.73 m2 protein load in the form of a meat meal was studied in 19 normal subjects and 35 normoalbuminuric insulin-dependent diabetic patients (IDDs) under conditions of sustained euglycemia. The area under the glomerular filtration rate (GFR) curve rose above base line by 1,904 +/- 292 in normals and 502 +/- 237 ml/1.73 m2 in IDDs (P less than 0.01). The meat meal induced a greater increment in the area under the glucagon curve in normals (14,930 +/- 186 pg.ml-1.min-1) than in IDDs (7,227 +/- 67, P less than 0.01); similarly urinary excretion of prostaglandin E2 and

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Penney, David G., and Bernd G. Barthel. "Effects of thyroid and growth hormone deficiency, and food restriction on heart mass, with and without added stress (carboxyhemoglobinemia)." Canadian Journal of Physiology and Pharmacology 63, no. 6 (1985): 642–48. http://dx.doi.org/10.1139/y85-107.

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The roles of thyroid and growth hormone, and food restriction in maintenance of heart mass and in carbon monoxide-stimulated cardiac growth were examined. First, thyroidectomized and normal adult male rats inhaled up to 500 ppm CO in air for 42 days. Combined ventricular weights of thyroidectomized rats inhaling CO and air were 12 and 23% smaller than predicted, respectively, while the combined ventricular weight of normal rats inhaling CO was 29% larger than predicted. Thyroidectomy increased the mass of the left ventricle relative to the right ventricle; this was reversed by CO treatment. Wh

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Frederick, Angela. "Risky Mothers and the Normalcy Project." Gender & Society 31, no. 1 (2017): 74–95. http://dx.doi.org/10.1177/0891243216683914.

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Feminist scholars have been critical of the expectations placed upon mothers to accomplish a perfect version of motherhood, but have often failed to interrogate the values about normalcy and disability imbedded in modern mothering ideologies. Mothers with disabilities are well positioned to expose the underlying beliefs about normalcy with which all mothers must contend. Drawing from interviews and focus groups conducted with mothers who have physical and sensory disabilities, I explore Deaf/disabled women’s experiences negotiating the scientific motherhood regime. Illuminating a paradox, I ar

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Salgado Durán, Andrés. "Pórticos prefabricados: uniones de elementos que mejoran su reacción frente a cargas = Precast frame constructions: connections that improve reaction through loads." Anales de Edificación 3, no. 1 (2017): 44. http://dx.doi.org/10.20868/ade.2017.3534.

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ResumenEl éxito del rendimiento de las estructuras prefabricadas se basa en la forma en que estos elementos aisladosconfiguran un edificio entero mediante sus conexiones. En la superposición de dos piezas, a veces es difícil hacer que aparezcanfallas comunes denominadas separación y extracción. Con el fin de mejorar la eficiencia de las articulaciones, esta investigaciónmuestra nuevas formas de construir uniones mejores y más desarrolladas, listas para sostener no sólo cargas normales sinotambién externas como fuerzas sísmicas.AbstractThe success of performance of prefabricate structures is ba

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Liu, Y. Y., J. B. Cao, H. S. Fu, Z. Wang, Z. Z. Guo, and R. J. He. "Failures of Minimum Variance Analysis in Diagnosing Planar Structures in Space." Astrophysical Journal Supplement Series 267, no. 1 (2023): 13. http://dx.doi.org/10.3847/1538-4365/acdd58.

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Abstract Minimum variance analysis of the magnetic field (MVAB), among various techniques of planar structure analysis, is most widely used for its numerical simplicity and loose requirements for data. Through a large number of studies based on MVAB, a global picture of the solar wind intermittency has been established. However, the huge discrepancy between the results from MVAB and other techniques like timing/triangulation implies that the uncertainty of MVAB is a crucial issue that is not fully understood. Utilizing Cluster data, we establish a data set comprised of 6752 discontinuities, wh

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Aranguren, Aitor, Julia Cuevas, José María Tubía, Manuel Carracedo, and Francisco J. Larrea. "La faille de Conquista: Caractérisation structurale et cinématique d'un cisaillement ductile dextre à composante normale dans le domaine sud de l'Arc ibéro-armoricain." Comptes Rendus de l'Académie des Sciences - Series IIA - Earth and Planetary Science 325, no. 8 (1997): 601–6. http://dx.doi.org/10.1016/s1251-8050(97)89461-x.

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Theodore, J. G., P. Kaliraj, S. Jayachandran, and K. Jayaraman. "Cloning, over-expression and evaluation of a recombinant fusion protein of Wuchereria bancrofti towards its application as a diagnostic agent for bancroftian filariasis." Parasitology 106, no. 4 (1993): 413–20. http://dx.doi.org/10.1017/s0031182000067160.

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SUMMARYA low molecular weight (15 kDa) surface antigen of the cattle filarial nematode, Setaria digitata, was earlier shown to be specifically recognized by the antibodies from human bancroftian filarial (Mf positive) patients' sera (Theodore & Kaliraj, 1990). The filarial specific antibodies bound to a 15 kDa peptide in preparative Western blots were eluted and employed in screening of candidate antigens expressed in the genomic library of Wuchereria bancrofti at the IgG4 subclass antibody level. A recombinant clone (λ WbG7) reacting strongly with filarial sera but poorly with sera from p

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de Saint Blanquat, Michel. "La faille normale ductile du massif du Saint Barthélémy. Evolution hercynienne des massifs nord-pyrénéens catazonaux considérée du point de vue de leur histoire thermique." Geodinamica Acta 6, no. 1 (1993): 59–77. http://dx.doi.org/10.1080/09853111.1993.11105239.

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RAMASWAMY, SHANKARAN, and JEFFERY K. HOVIS. "Ability of the D-15 panel tests and HRR pseudoisochromatic plates to predict performance in naming VDT colors." Visual Neuroscience 21, no. 3 (2004): 455–60. http://dx.doi.org/10.1017/s095252380421313x.

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Color codes in VDT displays often contain sets of colors that are confusing to individuals with color-vision deficiencies. The purpose of this study is to determine whether individuals with color-vision deficiencies (color defectives) can perform as well as individuals without color-vision deficiencies (color normals) on a colored VDT display used in the railway industry and to determine whether clinical color-vision tests can predict their performance. Of the 52 color defectives, 58% failed the VDT test. The kappa coefficients of agreement for the Farnsworth D-15, Adams desaturated D-15, and

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Penot-Lacassagne, Olivier. "Novölittérature… à la brisure des années 1970." Études françaises 54, no. 1 (2018): 135–52. http://dx.doi.org/10.7202/1042870ar.

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Comment « l’aventure punk » française a-t-elle été écrite ? Quel en fut le récit « littéraire » ? Par quels mots s’est-elle dite ? Jean-François Bizot, Patrice Eudeline, Kriss Vilà et Yves Adrien ont relaté avec éclat les avatars de ces « années blanches », 1976-1980. Entre témoignage, manifeste, roman-photos et fiction fantastique, leurs récits rendent compte de la brisure punk : débâcle de l’utopisme des années 1960, présent effondré, horizon sans lendemain. Les protagonistes de leurs récits traversent le vaste champ des désillusions des années 1970 et 1980. Inaptes ou indifférents au recycl

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Jacobson, Gary P., and Devin L. McCaslin. "A Reexamination of the Long Latency N1 Response in Patients with Tinnitus." Journal of the American Academy of Audiology 14, no. 07 (2003): 393–400. http://dx.doi.org/10.1055/s-0040-1715758.

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There have been disparate findings reported previously by investigators who have examined differences in the cortically generated N1 (i.e., N100) from control and tinnitus samples. Investigators have employed differing stimulation paradigms applied to relatively small subject samples. Accordingly, it is not surprising that there has been no unanimity in the reported findings. The present investigation was conducted to determine, once again, whether differences exist in the cortically generated N1 potential recorded from both normals and subjects with bothersome tinnitus. In this investigation

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Phillips, P. C. B. "Partially Identified Econometric Models." Econometric Theory 5, no. 2 (1989): 181–240. http://dx.doi.org/10.1017/s0266466600012408.

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This paper studies a class of models where full identification is not necessarily assumed. We term such models partially identified. It is argued that partially identified systems are of practical importance since empirical investigators frequently proceed under conditions that are best described as apparent identification. One objective of the paper is to explore the properties of conventional statistical procedures in the context of identification failure. Our analysis concentrates on two major types of partially identified model: the classic simultaneous equations model under rank condition

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Imamura, T., A. Yamadori, Y. Shiga, M. Sahara, and H. Abiko. "Is Disturbed Transfer of Learning in Callosal Agenesis due to a Disconnection Syndrome?" Behavioural Neurology 7, no. 2 (1994): 43–48. http://dx.doi.org/10.1155/1994/146072.

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Disturbed intermanual transfer of tactile learning in callosal agenesis has been interpreted as a sign of disconnection syndrome. We observed this sign in one of four acallosal patients with a conventional form-board task, and tried to elucidate the nature of the deficit. The form-board performance of the patient with disturbed transfer of learning totally depended on motor skill, while the other acallosals and normal controls executed the task based on spatial and somesthetic information. All acallosals and normals, however, failed to show transfer of learning with another tactile task which

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Gilbert, I. A., J. M. Fouke, and E. R. McFadden. "Heat and water flux in the intrathoracic airways and exercise-induced asthma." Journal of Applied Physiology 63, no. 4 (1987): 1681–91. http://dx.doi.org/10.1152/jappl.1987.63.4.1681.

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To explore the relationship between the flux of heat and water within the respiratory tract during exercise and recovery to the development of exercise-induced asthma (EIA), we recorded airstream temperature at multiple points throughout the tracheobronchial tree in 10 normal and 10 asthmatic subjects before, during, and after cycle ergometry. In both groups, the intra-airway temperature fell progressively as ventilation increased, and there were no significant differences between the thermal profiles of the two populations at rest or during exercise. Calculation of water losses and the osmola

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Fitzpatrick, E. A., J. S. Bryson, C. Rhoads, A. M. Kaplan, and D. A. Cohen. "T-deficient transmembrane signaling in CD4+ T cells of retroviral-induced immune-deficient mice." Journal of Immunology 148, no. 11 (1992): 3377–84. http://dx.doi.org/10.4049/jimmunol.148.11.3377.

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Abstract The defective virus found in the LP-BM5 mixture of murine leukemia viruses induces a severe immune deficiency disease in C57BL/6 mice that is characterized by the activation and expansion of T and B cells that become unresponsive to normal immune stimuli. The nature of the biochemical lesion in these defective lymphocyte populations remains unknown. Flow cytometric analysis of the T cell population in infected animals has demonstrated expansion of both CD4+ and CD8+ subsets. Despite chronic expansion in vivo, CD4+ T cells by wk 4 postinfection failed to up-regulate cell surface IL-2R

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Ozcan, Muhit, Colleen Morton, Anna Solovey, et al. "Whole Blood Tissue Factor Procoagulant Activity Remains Detectable during Severe Aplasia following Bone Marrow and Peripheral Blood Stem Cell Transplantation." Thrombosis and Haemostasis 85, no. 02 (2001): 250–55. http://dx.doi.org/10.1055/s-0037-1615705.

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SummaryUsing a novel whole blood assay, we recently demonstrated that tissue factor procoagulant activity (TF PCA) is present in normal individuals. Preliminary experiments suggested that this activity is localized in the mononuclear cell fraction. Postulating that whole blood TF PCA would therefore be undetectable when monocytes and neutrophils are absent from peripheral blood, we assayed TF PCA during the peri-transplant period in 15 consecutive patients undergoing allogeneic (n = 12) or autologous (n = 3) bone marrow transplantation (BMT) or peripheral blood stem cell transplantation (PBSCT

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ELLIOTT, R., B. J. SAHAKIAN, A. MICHAEL, E. S. PAYKEL, and R. J. DOLAN. "Abnormal neural response to feedback on planning and guessing tasks in patients with unipolar depression." Psychological Medicine 28, no. 3 (1998): 559–71. http://dx.doi.org/10.1017/s0033291798006709.

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Background. It has been suggested that patients with unipolar depression show abnormal responses to negative feedback in the performance of cognitive tasks. Positron emission tomography (PET) has previously identified blood flow abnormalities in depressed patients during cognitive performance. We have also used PET to identify regions where there is differential neural response to performance feedback in normal volunteers. In this study we aimed to test the hypothesis that blood flow in these regions, the medial caudate and ventromedial prefrontal cortex, would be abnormal in depressed patient

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Alam, R., J. B. Welter, P. A. Forsythe, M. A. Lett-Brown, and J. A. Grant. "Comparative effect of recombinant IL-1, -2, -3, -4, and -6, IFN-gamma, granulocyte-macrophage-colony-stimulating factor, tumor necrosis factor-alpha, and histamine-releasing factors on the secretion of histamine from basophils." Journal of Immunology 142, no. 10 (1989): 3431–35. http://dx.doi.org/10.4049/jimmunol.142.10.3431.

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Abstract Most cytokines possess multiple biologic activities. This study was undertaken to investigate the effect of rIL-1 beta, -2, -3, -4 and -6, IFN-gamma, TNF-alpha, and granulocyte-macrophage (GM)-CSF on basophils from 16 donors and the amount of histamine released was compared with that by partially purified mononuclear cell-derived histamine-releasing factor (HRF) and anti-IgE. We found that only IL-3 and GM-CSF at relatively high doses (50 to 500 ng/ml) released small amounts of histamine (3 to 14%) from two allergic donors. In contrast, both HRF and anti-IgE released significant amoun

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PATEL, Dilip D., Brian L. KNIGHT, Anne K. SOUTAR, Geoffrey F. GIBBONS та David P. WADE. "The effect of peroxisome-proliferator-activated receptor-α on the activity of the cholesterol 7α-hydroxylase gene". Biochemical Journal 351, № 3 (2000): 747–53. http://dx.doi.org/10.1042/bj3510747.

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Cholesterol 7α-hydroxylase (Cyp7a1) plays a central role in the regulation of bile acid and cholesterol metabolism, and transcription of the gene is controlled by bile acids and hormones acting through a complex interaction with a number of potential steroid-hormone-binding sites. Transcriptional activity of the human CYP7A1 gene promoter transfected into HepG2 cells was decreased in a concentration-dependent manner by co-transfection with an expression vector for peroxisome-proliferator-activated receptor-α (PPARα). This effect was augmented by 9-cis-retinoic acid receptor-α (RXRα) and activa

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Van Rooyen, Deanne, and Sharon D. Carr. "Deconstructing the Infrastructure: A Complex History of Diachronous Metamorphism and Progressive Deformation during the Late Cretaceous to Eocene in the Thor-Odin–Pinnacles Area of Southeastern British Columbia." Geoscience Canada 43, no. 2 (2016): 103. http://dx.doi.org/10.12789/geocanj.2016.43.097.

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The Thor-Odin dome is a basement-cored tectonothermal culmination in southern British Columbia containing high-grade metamorphic rocks that were polydeformed in the Late Cretaceous to Eocene. The rocks south of the Thor-Odin dome that extend ca. 20 km to the Pinnacles culmination and Whatshan batholith comprise a heterogeneous tract of polydeformed medium- to high-grade metamorphic rocks and host the South Fosthall pluton near the base of the structural section. They lie in the footwall of the Columbia River fault (CRF) zone, a moderately east-dipping, ductile-brittle, normal fault that was ac

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Roza, Carolina, Jennifer M. A. Laird, and Fernando Cervero. "Spinal Mechanisms Underlying Persistent Pain and Referred Hyperalgesia in Rats With an Experimental Ureteric Stone." Journal of Neurophysiology 79, no. 4 (1998): 1603–12. http://dx.doi.org/10.1152/jn.1998.79.4.1603.

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Roza, Carolina, Jennifer M. A. Laird, and Fernando Cervero. Spinal mechanisms underlying persistent pain and referred hyperalgesia in rats with an experimental ureteric stone. J. Neurophysiol. 79: 1603–1612, 1998. Spinal neurons processing information from the ureter have been characterized in rats 1–4 days after the implantation of an experimental ureteric stone and compared with those of normal rats. The effects of a conditioning noxious stimulation of the ureter in the presence of the hyperalgesia evoked by the calculosis also were examined. Extracellular recordings were performed at the T1

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MONCALEANO, J. S., L. M. JIMÉNEZ, and C. A. SÁNCHEZ. "Mosaicismo leucocitario asociado a infertilidad en cuatro yeguas." Orinoquia 11, no. 1 (2007): 87–91. http://dx.doi.org/10.22579/20112629.173.

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Titulo en ingles: Mosaicism leucocitary associated to infertility in four mares.RESUMEN: Se tomaron muestras de sangre periférica a cuatro yeguas de 19, 13, 10 y 4 años de edad, de raza Silla francesa, dos Criollas Colombianas y una Paso Fino Colombiano respectivamente, para realizar cultivo de linfocitos. Los animales fueron remitidos por la Clínica de Reproducción al Laboratorio de Citogenética Animal de la Facultad de Medicina Veterinaria y de Zootecnia de la Universidad Nacional de Colombia por antecedentes de problemas reproductivos. A la palpación se detectaron órganos reproductivos subd

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Greipp, Patricia, Greg Cascino, Teresa Kimlinger, et al. "Plasma Cell Folate Receptor Overexpression Differentiates Multiple Myeloma from Monoclonal Gammopathy of Undetermined Significance and Smoldering Myeloma." Blood 104, no. 11 (2004): 3649. http://dx.doi.org/10.1182/blood.v104.11.3649.3649.

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Abstract Background: Folate receptor (FR) is a recently recognized tumor marker that is being investigated for targeted delivery of drugs, imaging of cancer cells, and tumor immunotherapy. The small size of the molecule, simple conjugation chemistry and lack of immunogenicity make folate an ideal candidate for targeted delivery to tumors bearing the FR (Lu Y, Low PS. Folate-mediated delivery of macromolecular anticancer therapeutic agents. Adv Drug Deliv Rev. 2002 Sep 13;54(5):675–93). FR is overexpressed in 90% of ovarian cancers and in other human tumors including endometrial, colorectal, br

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Verfaillie, C., W. Miller, N. Kay, and P. McGlave. "Adherent lymphokine-activated killer cells in chronic myelogenous leukemia: a benign cell population with potent cytotoxic activity." Blood 74, no. 2 (1989): 793–97. http://dx.doi.org/10.1182/blood.v74.2.793.793.

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Abstract We generated a homogeneous population of cells with cytotoxic activity termed “adherent lymphokine-activated killer” (ALAK) cells from the peripheral blood of nine patients in the chronic phase of Ph1 positive chronic myelogenous leukemia (CML). The selective enrichment of CML ALAK cells depended on their propensity to adhere to plastic and proliferate when cultured in the presence of recombinant interleukin-2 (rIL-2) for 14 days. Culture of peripheral blood mononuclear cells under these conditions resulted in growth of a uniform population of cells with morphologic characteristics of

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Verfaillie, C., W. Miller, N. Kay, and P. McGlave. "Adherent lymphokine-activated killer cells in chronic myelogenous leukemia: a benign cell population with potent cytotoxic activity." Blood 74, no. 2 (1989): 793–97. http://dx.doi.org/10.1182/blood.v74.2.793.bloodjournal742793.

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We generated a homogeneous population of cells with cytotoxic activity termed “adherent lymphokine-activated killer” (ALAK) cells from the peripheral blood of nine patients in the chronic phase of Ph1 positive chronic myelogenous leukemia (CML). The selective enrichment of CML ALAK cells depended on their propensity to adhere to plastic and proliferate when cultured in the presence of recombinant interleukin-2 (rIL-2) for 14 days. Culture of peripheral blood mononuclear cells under these conditions resulted in growth of a uniform population of cells with morphologic characteristics of large gr

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Cutler, Jacky A., Mike J. Mitchell, and Geoffrey F. Savidge. "A Novel Frameshift Mutation in a Case of Familial May-Hegglin Anomaly." Blood 104, no. 11 (2004): 3033. http://dx.doi.org/10.1182/blood.v104.11.3033.3033.

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Abstract The May-Hegglin anomaly is a rare, autosomal dominant condition that is characterised by thrombocytopaenia, anisocytosis, and Dohlë-like inclusion bodies in leukocytes. The disorder generally results in a mild bleeding tendency. May-Hegglin anomaly results from defects in the MYH9 gene, which encodes the heavy chain of nonmuscle myosin IIA. The gene maps to chromosome 22q12.3-q13.2, comprises 40 exons, and produces a 5.8kb mRNA transcript. We present a case of familial May-Hegglin anomaly. This kindred was first identified, and published, in 1964; but no further analyses were carried

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Pai, Howard Huaihan, Tom Pickles, Mira Keyes, et al. "Randomized study evaluating testosterone recovery using short-versus long-acting luteinizing hormone releasing hormone agonists." Canadian Urological Association Journal 5, no. 3 (2013): 173. http://dx.doi.org/10.5489/cuaj.639.

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Introduction: We sought to compare the rate of return of testosteronelevels and sexual function in men with prostate cancerreceiving longer acting, 3-month preparation of luteinizing hormone-releasing hormone agonist (L-LHRH-A) versus shorter acting,1-month preparation of luteinizing hormone-releasing hormoneagonist (S-LHRH-A).Methods and Materials: Men with low to intermediate risk localizedprostate cancer were randomized to either L-LHRH-A (2-3 monthduration LHRH-A) or S-LHRH-A (6-1 month duration LHRH-A) ofandrogen suppression therapy (AST) and prostate brachytherapyusing iodine-125 radiois

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Silbermann, Rebecca, Marina Bolzoni, Paola Storti, et al. "Bone Marrow Monocyte / Macrophage Derived Activin A Mediates the Osteoclastogenic Effects of IL-3 in Myeloma,." Blood 118, no. 21 (2011): 3933. http://dx.doi.org/10.1182/blood.v118.21.3933.3933.

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Abstract Abstract 3933 Multiple myeloma (MM) is characterized by bone destruction with suppressed new bone formation that is mediated by multiple factors including MIP-1α (CCL3), RANKL, IL-3, DKK1 and recently, Activin A (ActA). IL-3 is a bifunctional cytokine that indirectly increases osteoclastogenesis and suppresses osteoblastogenesis via CD14+ bone marrow monocytes (BMM). Additionally, IL-3 levels are elevated in the BM plasma of MM patients compared with normals, however the mediators of IL-3's effects on myeloma bone disease are unknown. To investigate this we performed gene expression p

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Gutiérrez-Abril, Jesús, Gunes Gundem, Elise Fiala, et al. "A D e Novo Supernumerary Ring Chromosome 1 Causes B-Cell Acute Lymphoblastic Leukemia in Monozygotic Twins Due to Independent and Partially Convergent Evolutionary Trajectories." Blood 142, Supplement 1 (2023): 4352. http://dx.doi.org/10.1182/blood-2023-181194.

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Introduction B-cell acute lymphoblastic leukemia (B-ALL) is the most common pediatric cancer. In recent years, our understanding of B-ALL biology has benefited from genomic and transcriptomic analyses that identify driver alterations in 98% of patients. In addition, prior studies of monozygotic twins, who both developed B-ALL, have provided insight into the developmental timing and natural history of the disease, as well as the identification of novel mechanisms of leukemogenesis. Herein we study a case of monozygotic twins, who developed B-ALL (Table 1). We report the characterization of a de

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Konstantinovskaya, Elena, Gennady Ivanov, Jean-Louis Feybesse, and Jean-Luc Lescuyer. "Structural Features of the Central Labrador Trough: A Model for Strain Partitioning, Differential Exhumation and Late Normal Faulting in a Thrust Wedge under Oblique Shortening." Geoscience Canada, March 29, 2019, 5–30. http://dx.doi.org/10.12789/geocanj.2019.46.143.

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The west-verging fold and thrust belt of the Central Labrador Trough originated as a part of the New Quebec Orogen from rift inversion as a result of oblique collision and dextral transpression between the Archean Superior craton and the Archean block of the Core Zone during the Trans-Hudson orogeny (1.82−1.77 Ga). The structures associated with dextral transpression are well established in the northern segment of the orogen but not in the central part. We present new field structural observations along the ca. 70 km long W−E Minowean-Romanet transect that include not only elements of thrust t

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"Homeostasis and Homeorhesis: Sustaining Order and Normalcy in Human-Engineered Complex Systems." International Journal on Engineering Technologies and Informatics 2, no. 3 (2021). http://dx.doi.org/10.51626/ijeti.2021.02.00014.

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This letter explores the notions of biological homeostasis and homeorhesis for construction of hybrid decision & control laws for human-engineered complex systems. The complexity may remain dormant during normal operations, but it becomes acutely conspicuous when contributing to unanticipated cascading and pervasive failures. The objective here is to sustain order and normalcy under both anticipated and unanticipated anomalies, faults, and disturbances. As an example, macroscopic decision & control of material microstructures is presented.

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Anderson, Ronald. "Numéro 96 - juin 2012." Regards économiques, October 12, 2018. http://dx.doi.org/10.14428/regardseco.v1i0.14873.

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Partant du constat que toutes les crises financières se ressemblent (endettement excessif, vente panique d’actifs, etc.), je cherche à déterminer ce qui caractérise la crise financière de 2007. Je passe en revue les étapes du développement de la crise, depuis les premiers signaux d’alerte sur le marché du crédit hypothécaire nord-américain jusqu’à la crise des dettes souveraines de l’Eurozone. Je relève quatre leçons majeures qui, selon moi, devraient être attentivement étudiées par tous ceux qui s’intéressent à la gestion des institutions financières majeures, à la définition de nouvelles règ

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Anderson, Ronald. "Numéro 96 - juin 2012." Regards économiques, October 12, 2018. http://dx.doi.org/10.14428/regardseco2012.06.01.

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Partant du constat que toutes les crises financières se ressemblent (endettement excessif, vente panique d’actifs, etc.), je cherche à déterminer ce qui caractérise la crise financière de 2007. Je passe en revue les étapes du développement de la crise, depuis les premiers signaux d’alerte sur le marché du crédit hypothécaire nord-américain jusqu’à la crise des dettes souveraines de l’Eurozone. Je relève quatre leçons majeures qui, selon moi, devraient être attentivement étudiées par tous ceux qui s’intéressent à la gestion des institutions financières majeures, à la définition de nouvelles règ

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