Relevant bibliographies by topics / Falciparum and P

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Falciparum and P'

Author: Grafiati
Published: 4 June 2021
Last updated: 26 July 2025

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Journal articles on the topic "Falciparum and P"

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Gangesh, Kumar Gunjan, and Kumar Jha Anand. "A Retrospective Assessment of Clinical Profile of P. Falciparum, P. Vivax and Mixed Infections of Malaria." International Journal of Current Pharmaceutical Review and Research 16, no. 2 (2024): 384–88. https://doi.org/10.5281/zenodo.12740030.

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Aim: The objective of this study was to compare the clinical profile of P. falciparum, P. vivax and mixedinfections of malaria.Methods: This retrospective observational study included malaria patients who were admitted to Department ofGeneral Medicine, Jannayak Karpoori Thakur Medical College and Hospital Madhepura,, Bihar, India for 12months. Inpatient retrieved and scrutinized on the basis of the patient’s demographic profile, clinical findings,investigations, treatment, and complications during this 12- month period.Results: The subjects consisted of 60 P. vivax and 40 P. falciparum c
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ARICAN ÇELİK, Aslı, Rıfat TAMALI, Gülruhsar YILMAZ, Pınar KARABACAK, and Mustafa Soner ÖZCAN. "A Rare Cause of Fever in ICU; Malaria." Acta Medica Nicomedia 5, no. 3 (2022): 235–37. http://dx.doi.org/10.53446/actamednicomedia.1103400.

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Sıtma, anofel cinsi sivrisineklerin insanları sokması sonucu bulaşan paraziter bir hastalıktır. Plasmodium falciparum (P Falciparum) en ölümcül tabloya yol açan türüdür, ülkemizde nadir görülür ve genellikle yurtdışı kaynaklıdır. Yoğun bakımda yüksek ateş pek çok klinik durumda karşımıza çıksa da nadir görülen bir durum olan P. Falciparuma bağlı sıtma aklımızda bulunmalıdır Bu olgu sunumunda, yurt dışı seyahat öyküsü bulunan P. Falciparum sıtma tanısı konulan hastanın yoğun bakım takip ve tedavi süreci sunulmuştur.
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Taguchi, Nao, Toshimitsu Hatabu, Haruyasu Yamaguchi, Mamoru Suzuki, Kumiko Sato, and Shigeyuki Kano. "Plasmodium falciparum: selenium-induced cytotoxicity to P. falciparum." Experimental Parasitology 106, no. 1-2 (2004): 50–55. http://dx.doi.org/10.1016/j.exppara.2004.01.005.

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Dr., Deepak Kumar Gindora, Mayank Gupta Dr., Sunil Kumar Mahavar Dr., Jai Purohit Dr., and Raman Sharma Dr. "Biochemical characteristics of Malaria patients with their association with severity of disease." International Multispeciality Journal of Health 3, no. 7 (2017): 215–22. https://doi.org/10.5281/zenodo.837945.

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<strong><em>Abstract—</em></strong><em> Malaria is one of the oldest and most widespread disease which affects more than 2400 million people, over 40% of world's population, in more than 100 countries in tropics from South America to Indian Peninsula.</em><em> This study was designed to assess the </em><em>platelet counts, haematocrit &amp; liver enzymes (Alanine transaminase, Aspartate transaminase, Alkaline phosphatase) in patients of Plasmodium vivax &amp; Plasmodium falciparum malaria and its association with the severity and prognosis of disease. I</em><em>n a hospital based observational
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Cserti, Christine M., and Walter H. Dzik. "The ABO blood group system and Plasmodium falciparum malaria." Blood 110, no. 7 (2007): 2250–58. http://dx.doi.org/10.1182/blood-2007-03-077602.

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In the century since the discovery of the ABO blood groups, numerous associations between ABO groups and disease have been noted. However, the selection pressures defining the ABO distributions remain uncertain. We review published information on Plasmodium falciparum infection and ABO blood groups. DNA sequence information dates the emergence and development of the group O allele to a period of evolution before human migration out of Africa, concomitant with P falciparum's activity. The current geographic distribution of group O is also consistent with a selection pressure by P falciparum in
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Zakeri, S., S. Mamaghani, A. A. Mehrizi, et al. "Molecular evidence of mixed P. vivax and P. falciparum infections in northern Islamic Republic of Iran." Eastern Mediterranean Health Journal 10, no. 3 (2004): 336–42. http://dx.doi.org/10.26719/2004.10.3.336.

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This study compared basic microscopy with molecular detection of Plasmodium species. According to thick-film microscopy, 100% of 142 malaria cases in Pars-Abad, Ardebil province, were infected with a single species, P vivax. However, nested polymerase chain reaction [PCR] detected mixed species infections of both P. vivax and P. falciparum in 7.0%. In Maz and eran province, 2/20 blood films were diagnosed with only P. falciparum and 18/20 with only P. vivax. However, nested PCR detected 17/20, 2/20 and 1/20 with P. vivax only, P. falciparum only and mixed species respectively. The unexpected p
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Goyal, Jagdish Prasad, and Aarti M. Makwana. "Comparison of Clinical Profile between P. vivax and P. falciparum Malaria in Children: A Tertiary Care Centre Perspective from India." Malaria Research and Treatment 2014 (April 9, 2014): 1–4. http://dx.doi.org/10.1155/2014/132672.

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Background. Malaria is a one of the leading causes of morbidity and mortality in tropical countries. Plasmodium vivax (P. vivax) is usually thought to be causing benign malaria with low incidence of complications as compared to Plasmodium falciparum (P. falciparum). Methods. This retrospective observational study included malaria patients who were admitted to K.T. Children Hospital and P.D.U. Government Medical College, Rajkot, a tertiary care teaching hospital, Gujarat, western India, during the period January 2012 to December 2012. Inclusion criteria were patients in whom either P. falciparu
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Dr., Tehmina Hayat Dr. Arshia Maqbool Dr. Muhammad Adnan Akbar. "PREVALANCE OF MALARIA IN EASTERN AREAS OF BALUCHISTAN AT BORDERS OF OTHER PROVINCES." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 05 (2018): 4395–400. https://doi.org/10.5281/zenodo.1254447.

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Objective:<em> The objective of the study was to decide the occurrences of parasites causing malaria in far flung human populations of Balochistan. </em> Methodology:<em> A large group of 3340 subjects was examined for malarial parasites by testing the blood samples during the timeframe of 2 years i.e. July 2015 to June 2017.</em> Results:<em> The laboratory tests revealed that 1095 (32.78%) cases were diagnosed with malaria out of total suspected sample of 3340. Among 1095 infected cases, 579 were due to </em>Plasmodium falciparum<em> infection and 516 cases were infected with </em>Plasmodium
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Dr, Fatima Altaf Dr. Namra Tufail Dr. Shifa Batool. "PREVALANCE OF MALARIA IN EASTERN AREAS OF BALUCHISTAN AT BORDERS OF OTHER PROVINCES." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 05 (2018): 4593–98. https://doi.org/10.5281/zenodo.1257636.

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Objective:<em> The objective of the study was to decide the occurrences of parasites causing malaria in far flung human populations of Balochistan. </em> Methodology:<em> A large group of 3340 subjects was examined for malarial parasites by testing the blood samples during the timeframe of 2 years i.e. July 2015 to June 2017.</em> Results:<em> The laboratory tests revealed that 1095 (32.78%) cases were diagnosed with malaria out of total suspected sample of 3340. Among 1095 infected cases, 579 were due to </em>Plasmodium falciparum<em> infection and 516 cases were infected with </em>Plasmodium
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Payal, Jivani, Panchal Bijal, Parmar Sudha, Mehta Neeta, Savaliya Chirag, and Sorani Ashvin. "A COMPARATIVE STUDY OF EFFECT OF P. FALCIPARUM AND P. VIVAX MALARIA ON PLATELET COUNT." International Journal of Basic & Applied Physiology 3, no. 1 (2014): 243–47. https://doi.org/10.5281/zenodo.4486391.

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<strong>Background &amp; objectives</strong>: Malaria is a big menace in India affecting almost 24 million peoples and causing 2.4 deaths per 1, 00,000 populations annually. Malaria affects almost all the organs of body but varieties of typical hematological alterations have been reported. Present study aims to evaluate impact of malaria on platelet count and species specific changes if any. <strong>Methods:</strong> This study was carried out in Deendayal Upadhyay Govt. Medical College and Hospital, Rajkot 100 known hospitalized cases of malaria. All the hematological parameters including pla
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Dissertations / Theses on the topic "Falciparum and P"

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Casals-Pascual, Climent. "Ineffective erythropoiesis in P. falciparum malarial anaemia." Thesis, University of Oxford, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.409709.

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Marques, João Pedro Nogueira. "Identificação de determinantes de resistência em P. falciparum." Master's thesis, Universidade de Aveiro, 2012. http://hdl.handle.net/10773/10904.

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Mestrado em Bioquímica<br>O presente estudo teve como objetivo a análise de possíveis determinantes de resistência por parte do Plasmodium falciparum ao fármaco antimalarico mefloquina. Para tal foi utilizada a estirpe W2, resistente à cloroquina e sensível à mefloquina, e uma estirpe isogénica W2mef, derivada de W2 e obtida por pressão seletiva em meio rico em mefloquina. Procedeu-se a um fracionamento subcelular e analisaram-se os extractos obtidos, com recurso a marcação com isótopos, O18 e iTRAQ, seguida de LC MS/MS MALDI, tendo sido identificadas 248 proteínas, sendo 76 de P. falciparum e
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Jaurigue, Jonnel Anthony [Verfasser]. "Antibodies against P. falciparum glycosylphosphatidylinositol epitopes / Jonnel Anthony Jaurigue." Berlin : Freie Universität Berlin, 2020. http://d-nb.info/1202463886/34.

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Seidlein, Lorenz von. "Transmission reduction of P. Falciparum by targeted drug intervention." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270781.

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Noble, Robert John. "Antigenic variation and its evolution in P. falciparum malaria." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:271b8ef9-4e14-42e3-80e6-5584119e20ca.

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This thesis investigates antigenic variation and its evolution in Plasmodium falciparum, the cause of the most deadly form of human malaria. Antigenic variation is a strategy for evading immunity by switching between antigenic variants during infection. In P. falciparum, such variable antigens confer different binding phenotypes that may affect parasite survival and have also been linked to pathology. Here, a new statistical method is described for determining the switching patterns that underlie antigenic variation. This method is then applied to experimental data to yield a full description
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Amrane, Dyhia. "Pharmacomodulation d'hétérocycles α-trichlorométhylés ciblant l'apicoplaste chez P. falciparum". Electronic Thesis or Diss., Aix-Marseille, 2021. http://www.theses.fr/2021AIXM0379.

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Le paludisme est la première parasitose en termes de mortalité à l’échelle mondiale. Les thérapies combinées à base d'artémisinine, traitement de première ligne du paludisme à Plasmodium falciparum, font face à des échecs dûs à l’apparition de résistances. Il est donc nécessaire de développer de nouvelles molécules antiplasmodiales possédant un mécanisme d’action novateur. Dans cet objectif, notre laboratoire a précédemment décrit la synthèse et les activités biologiques d'une chimiothèque de molécules azahétérocycliques α-trichlorométhylées, dont une molécule hit en série quinazoline qui prés
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Pugh, Kathryn Maria. "Developing chemical biological tools to probe phosphorylation in P. falciparum." Thesis, University of Leicester, 2014. http://hdl.handle.net/2381/28933.

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In 2010 there were an estimated 219 million cases of malaria worldwide, accounting for approximately 0.66 million deaths. With growing resistance to current antimalarial agents a challenge is placed on the scientific community to provide efficacious and cost effective methods for the diagnosis and treatment of malaria. As protein phosphorylation regulates most aspects of cell life, understanding the function of protein kinases in malaria parasites has the potential to uncover novel drug targets. To this end, this work focused on the study of three essential Plasmodium falciparum kinases using
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Lemieux, Jacob E. "Gene expression in P. falciparum : statistical patterns and molecular determinants." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:f6827b50-ca5f-4fe2-a52c-1947fef224ab.

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This thesis investigates patterns and mechanisms of gene expression in P. falciparum. The rapidly cycling patterns of genes during the asexual stages confounds the analysis of gene expression in culture and in patients. In order to overcome this problem, we develop statistical models to estimate the temporal progression of malaria parasites by using the observed gene expression values and known reference sets. We extend this framework to account for lineage commitment, and show that, similar to asexual development, it is also possible to recover information about parasite sexual differentiatio
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Sussmann, Rodrigo Antonio Ceschini. "Biossíntese de vitamina E nos estágios intraeritrocitários de P. falciparum." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/42/42135/tde-05082011-105023/.

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O estudo da biossíntese de isoprenóides em P. falciparum por meio da via 2C-metil-D-eritritol-4-fosfato (MEP) é apontado como possível alvo terapêutico, visto a via ser ausente em humanos. Foi descrito que nos estágios intraeritrocitários de P. falciparum a via essencial de biossíntese de isoprenóides é a via MEP. As vias do Chiquimato e MEP são precursoras da biossíntese de vitamina E e ambas já foram descritas em P. falciparum. É sugerido que a biossíntese de vitamina E possa ocorrer no parasita, representando um possível alvo para o desenvolvimento de novas drogas antimaláricas. Empregando
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Saif, A. M. "Pharmacology and pharmacodynamics of selected antimalarials against P. falciparum gametocytes." Thesis, University of Liverpool, 2017. http://livrepository.liverpool.ac.uk/3005700/.

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Malaria is a vector-borne disease that is still responsible for high human morbidity and mortality. Of the five Plasmodium species that can cause malaria in humans, Plasmodium falciparum is regarded the most virulent species. The most fundamental component of sustained control and eradication efforts is the development of effective drugs for malaria treatment and prophylaxis. Plasmodium falciparum’s sexual stages (gametocytes) are not associated with malarial pathogenesis or the clinical symptoms, but they are responsible for the transmission of the disease from human hosts to mosquitos. As su
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Books on the topic "Falciparum and P"

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Shujatullah, Fatima, and Haris M. Khan. Laboratory Diagnostic Approaches in Plasmodium falciparum Malaria: Rapid Diagnosis of P. falciparum. LAP Lambert Academic Publishing, 2012.

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Fritsch, Karl-Gerd. Zur Biochemie der Malaria-Blutstadien: Isolierung und Charakterisierung von Glutathionreduktase aus Malaria-Parasiten P. vinckei, P. berghei und P. falciparum mit Hilfe einer modifizierten HPLC-Anlage. 1989.

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Sakhuja, Vinay, and Harbir Singh Kohli. Malaria. Edited by Vivekanand Jha. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0183_update_001.

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Of the four pathogenic malarial species, clinically significant renal dysfunction is mainly associated with Plasmodium malariae and Plasmodium falciparum infections.P. falciparum infection frequently causes acute kidney injury (AKI). AKI may be the sole manifestation with a complete recovery after treatment or it may be a part of multi-organ failure which is often fatal. AKI due to Plasmodium vivax infection alone or as a result of mixed infection by vivax and falciparum can also occur.‘Quartan malarial nephropathy’ has been attributed to P. malariae infection although this relationship must b
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Book chapters on the topic "Falciparum and P"

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Bialasiewicz, Seweryn, David M. Whiley, and Theo P. Sloots. "Malaria (P. falciparum, P. vivax, P. malariae, P. ovale)." In PCR for Clinical Microbiology. Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-9039-3_64.

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Das, B. S., and D. I. Thurnham. "Plasma Lipid Peroxidation in P. Falciparum Malaria." In Lipid-Soluble Antioxidants: Biochemistry and Clinical Applications. Birkhäuser Basel, 1992. http://dx.doi.org/10.1007/978-3-0348-7432-8_32.

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Cruz, Daniel, Maíla Claro, Rodrigo Veras, et al. "P-FideNet: Plasmodium Falciparum Identification Neural Network." In Advances in Visual Computing. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-64556-4_29.

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Datta, Nidhi, and Virender Singh Chauhan. "Origin and evolution of human malaria parasite, P. falciparum and P. vivax." In Nature at Work: Ongoing Saga of Evolution. Springer India, 2010. http://dx.doi.org/10.1007/978-81-8489-992-4_19.

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Andisi, Kivisi C., and Abdirahman I. Abdi. "Analysis of var Gene Transcription Pattern Using DBLα Tags." In Methods in Molecular Biology. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2189-9_14.

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AbstractThe Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) antigens, which are encoded by a multigene family called var genes, are exported and inserted onto the surface of the infected erythrocytes. PfEMP1 plays a key role in the pathogenesis of severe malaria and are major targets of naturally acquired immunity. Studying the expression pattern of var genes in P. falciparum clinical isolates is crucial for understanding disease mechanism and immunity to malaria. However, var genes are highly variable, which makes it difficult to study their expression in clinical isolates obtai
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Keough, D. T., A. L. Ng, B. T. Emmerson, and J. de Jersey. "Expression and Properties of Recombinant P. Falciparum Hypoxanthine-Guanine Phosphoribosyltransferase." In Advances in Experimental Medicine and Biology. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-5381-6_141.

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Patra, Poly, and Gouri Sankar Bhunia. "Spatial Clustering of P. falciparum Malaria Epidemiology in Murshidabad District." In Advances in Geographic Information Science. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-75197-5_15.

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Usluca, Selma. "Malaria and Molecular Diagnosis." In Molecular Approaches in Medicine. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359524.2.

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It is an endemic vector-borne parasitic disease caused by protozoan parasites of the genus Plasmodium in tropical and subtropical regions worldwide. In each endemic area, malaria is transmitted by a specific set of Anopheles species. Plasmodium consists of over 200 species, infecting mammals, birds, and reptiles, and malaria parasites generally tend to be host-specific. Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, Plasmodium ovale, and Plasmodium knowlesi are the five known species of the genus Plasmodium that causes malaria in humans. Of the five Plasmodium species that cause
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Russo, Donna M., John S. Sundy, Henry C. Maguire, and William P. Weidanz. "Potentiation of Cell-Mediated Immune Responses Directed against P. Falciparum Sporozoite Peptide Vaccine by Immunomodulators." In Immunobiology of Proteins and Peptides V. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4757-2046-4_19.

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Corradin, G., G. Del Giudice, A. R. Togna, et al. "Heterogeneity and Specificity of Murine Cell Response to Synthetic Peptide (NANP)n of P. Falciparum Circumsporozoite Protein." In Macromolecular Biorecognition. Humana Press, 1987. http://dx.doi.org/10.1007/978-1-4612-4600-8_23.

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Conference papers on the topic "Falciparum and P"

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Santana, AH, BX Kemper, APS Lima, C. Simon, and SL Mioranza. "PREVALÊNCIA DA MALÁRIA EM UM HOSPITAL UNIVERSITÁRIO NO PARANÁ." In Resumos do 54º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2022. http://dx.doi.org/10.5327/1516-3180.140s1.6791.

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Objetivo: Avaliar a prevalência de casos de malária em um hospital do Paraná, por meio de teste imunocromatográfico e gota espessa. Método: A malária é transmitida através do mosquito do gênero Anopheles, sendo ocasionada no Brasil principalmente por Plasmodium falciparum e P. vivax. O P. falciparum é o responsável por desenvolver a forma mais grave da doença. Os protozoários se multiplicam dentro das hemácias, causando sintomas como febre, calafrios, tremores, dores no corpo e sudorese; eles também podem desencadear anemia hemolítica, edema pulmonar, hepatopatia e insuficiência renal aguda. O
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Nguyen, Tra, Kevin Shyong Wei Tan, and Pablo Bifani. "Hallmarks of Ivermectin Treatment on P. falciparum and Morphological Profiling of Ivermectin-Resistant Parasites." In 13th Asia Pacific Microscopy Congress 2025. ScienceOpen, 2025. https://doi.org/10.14293/apmc13-2025-0117.

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Martins, Claudio Fernando Graciano. "VACINA RTS, S/AS01: NOVA FERRAMENTA NO CONTROLE DA MALÁRIA." In II Congresso Brasileiro de Parasitologia Humana On-line. Revista Multidisciplinar em Saúde, 2022. http://dx.doi.org/10.51161/conbrapah/15.

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Introdução: A malária é uma doença transmitida por fêmeas dos mosquitos Anopheles infectadas por protozoários do gênero Plasmodium. Das cinco espécies que infectam humanos, P. falciparum representa uma maior ameaça. Apesar do progresso na redução da malária através das ferramentas e estratégias de prevenção disponíveis, a malária ainda é um grave problema de saúde pública. A vacina RTS, S/AS01 (Mosquirix TM), recentemente aprovada pela Organização Mundial da Saúde (OMS), surge como uma nova ferramenta contra a malária. A vacina age na fase pré-eritrocítica do ciclo de vida do P. falciparum evi
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Tesauro, C., S. Juul, B. Arno, et al. "Specific detection of topoisomerase i from the malaria causing P. falciparum parasite using isothermal Rolling Circle Amplification." In 2012 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2012. http://dx.doi.org/10.1109/embc.2012.6346451.

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Angwe, Martin Kamilo, Norah Mwebaza, Samson Nsombya, and Moses Ocan. "PA-324 CYP2B6*6 heterozygosity mediates slow P. falciparum clearance in malaria patients treated with Artemether-Lumefantrine." In Abstracts of The Eleventh EDCTP Forum, 7–10 November 2023. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/bmjgh-2023-edc.161.

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Silva, Saulo Brivaldo Mendonça da, Ana Bárbara Xavier da Silva, Mariana Souza Bezerra Cavalcanti, João Lucas Pessoa de Vasconcelos, Maria Clara Cavalcante Gomes, and Nathaly Bruna de Oliveira Silva. "A PROTEÍNA PfGARP COMO POSSÍVEL CANDIDATA À VACINA ANTIMALÁRICA." In XXVII Semana de Biomedicina Inovação e Ciência. Editora IME, 2021. http://dx.doi.org/10.51161/9786588884119/28.

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Introdução: A malária é uma parasitose que, apesar de antiga, continua sendo um grande risco para saúde pública com cerca de 445 mil mortes por ano ao redor do mundo(2). Apesar de possuir cinco agentes etiológicos, o Plasmodium falciparum é o principal, sendo responsável pelo maior número de mortes por malária(1,2). Uma vez que há diversos empecilhos quando se trata da erradicação da malária como resistência a inseticidas e a drogas antimaláricas, foi observada a necessidade de uma vacina contra o agravamento dessa parasitose(1). O fato de que a fase sanguínea do Plasmodium é atualmente aponta
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Luciano, Matheus Menezes, and Adria da Silva Santos. "CENÁRIO EPIDEMIOLÓGICO DA MALÁRIA NO BRASIL: UMA REVISÃO INTEGRATIVA DA LITERATURA." In I Congresso Brasileiro On-line de Ensino, Pesquisa e Extensão. Revista Multidisciplinar em Saúde, 2022. http://dx.doi.org/10.51161/ensipex/33.

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Introdução: A malária, também conhecida como paludismo, é uma doença infecciosa causado por protozoário e transmitida pela fêmea do gênero Anopheles. No Brasil, a malária é endêmica e tem sua concentração de casos na região amazônica, onde somente se encontram as espécies P. falciparum, P.malariae e P. vivax. A malária pode se manifestar clinicamente como episódios de calafrios seguidos por febre alta e sudorese profunda. Caso não for tratada adequadamente, pode evoluir para uma forma mais grave. Objetivos: Analisar as evidências científicas disponíveis sobre a situação epidemiológica da malár
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PINHEIRO, JOSÉ CIRÍACO, OSMARINA PEREIRA DA PAIXãO E. SILVA, ANTONIO FLORêNCIO DE FIGUEIREDO, et al. "ESTUDO SAR E QSAR DE ARTEMISININAS ANTIMALÁRIAS." In II Brazilian Congress of Development. DEV2021, 2021. http://dx.doi.org/10.51162/brc.dev2021-0001.

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Artemisininas com atividade contra cepas K-1 de P. falciparum foram modeladas com o método HF/3-21G. Para identificar as principais características das artemisininas necessárias para suas atividades, mapas de MEP foram construídos e usados. Os estudos de PCA e HCA mostraram que as variáveis energia do HOMO-1, DM, Q1, BA e nCs são responsáveis pela separação entre compostos mais ativos e menos ativos. Um modelo PLS com três componentes principais explicando 89% do total de informações foi construído para 18/5 compostos no conjunto de treinamento/validação externa. Como aplicação, analisamos os
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Ribeiro, Deborah Helen Fabiano. "MALÁRIA: NOVAS PERSPECTIVAS DE PREVENÇÃO." In I Congresso Brasileiro de Parasitologia Humana On-line. Revista Multidisciplinar em Saúde, 2021. http://dx.doi.org/10.51161/rems/713.

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Introdução: Em 2014 houve cerca de 214 milhões de casos de malária mundiais, com uma estimativa de 438.000 óbitos, muitos na África subsaariana. O Brasil, por seus aspectos climáticos, também sofre com a malária. Possuindo registros de programas de controle desde 1905, contextuando a durabilidade do problema. A espécie da malária com 84% dos casos nacionais é a Plasmodium vivax, diferente da maior parte do mundo que é lesada pela Plasmodium falciparum. O mosquito transmissor, do gênero Anopheles, costuma atacar em certos períodos do ano, introduzindo o parasita. Por esse fato, foi elaborada a
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Miranda, Heverton Lukas de Jesus, Emilly Deganutti Casarin, Vinicios Gomes Da Silva, and Alcione De Oliveira Dos Santos. "PERFIL EPIDEMIOLÓGICO E DISSEMINATIVO DA MALÁRIA ENTRE OS ANOS DE 2011 E 2020 EM REGIÕES TROPICAIS E SUBTROPICAIS." In I Congresso Brasileiro de Doenças Infectocontagiosas On-line. Revista Multidisciplinar em Saúde, 2021. http://dx.doi.org/10.51161/rems/2185.

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Introdução: A malária é uma doença tropical que está relacionada à Região Amazônica, embora seu contexto histórico abranja todo o território nacional. Caracteriza-se por uma patologia febril aguda causada por protozoários do gênero Plasmodium. Atualmente a malária é considerada um importante problema de saúde pública devido aos casos de morbilidade e mortalidade nos últimos anos, principalmente em regiões tropicais e subtropicais. Objetivos: Descrever o cenário epidemiológico da malária, e sua disseminação entre os anos de 2011 e 2020 em regiões tropicais e subtropicais. Material e métodos: Fo
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Reports on the topic "Falciparum and P"

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สืบหลินวงศ์, ธาดา, та จุฑาพันธุ์ พิณสวัสดิ์. รูปแบบของโปรตีนใน Plasmodium falciparum โดยอิเล็คโตรฟอรีซิสสองมิติ : รายงานวิจัยฉบับสมบูรณ์. จุฬาลงกรณ์มหาวิทยาลัย, 1988. https://doi.org/10.58837/chula.res.1988.10.

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โปรตีนในแต่ละเซลล์จะถูกสังเคราะห์ขึ้นอย่างรัดกุม มีการควบคุมในระดับยีน จึงมีคุณสมบัติเฉพาะตัวสำหรับแต่ละเซลล์หรือแต่ละชนิดของสัตว์และพืช ดังนั้น การศึกษารูปแบบของโปรตีนซึ่งถือเป็น gene product จึงอาจใช้เป็น marker ของเซลล์หรือสัตว์แต่ละชนิดได้ วัตถุประสงค์ของการวิจัยครั้งนี้เพื่อนำรูปแบบโปรตันซึ่งศึกษาโดยเทคนิค 2-D electrophoresis มาเป็น marker ของแต่ละสายพันธุ์บริสุทธิ์ของ P.falciparum โดยได้ศึกษารูปแบบโปรตีนของเม็ดเลือดแดงที่ติดเชื้อ P.falciparum ในตัวอย่างที่เป็น isolate และสายพันธุ์บริสุทธิ์รวม 70 ตัวอย่าง และศึกษาโปรตีนใน P. falciparum โดยใช้ [superscript 3 5]S-methionine incorporation, 2
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หาญยุทธนากร, พงชัย, та กาญจนา รังษีหิรัญรัตน์. การตรวจหาลำดับเบสของจีนไดไฮโดรไฟเลท รีดักเตส-ไทมิไดเลท ซินเทสของเชื้อมาเลเรียสายพันธุ์บริสุทธิ์ ที่มีระดับความไวต่อยาไพริเมทามีนต่างกัน ด้วยวิธีการหาลำดับเบสโดยตรง : รายงานผลการวิจัย. จุฬาลงกรณ์์มหาวิทยาลัย, 1998. https://doi.org/10.58837/chula.res.1998.31.

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ในอดีตยาไพริเมทามีน เป็นยาที่ให้ผลดีในการรักษษไข้มาลาเรียที่เกิดจาก Plasmodium falciparum โดยใช้ร่วมกับยาซัลฟาด็อกซิน แต่ในปัจจุบันยาดังกล่าวได้ลดความสำคัญในการใช้ลงเนื่องจากการแพร่กระจายของเชื้อมาลาเรียที่ดื้อต่อยาในส่วนต่าง ๆ ของโลกอย่างกว้างขวาง ไพริเมทามีนเป็นยาในกลุ่ม antifolate ที่สามารถยับยั้งการทำงานของเอนไซม์ dihydrofolate reductase-thymidylate synthase (DHFR-TS) ของเชื้อมาลาเรียซึ่งมีบทบาทสำคัญในการสังเคราะห์สารจำนวนนิวคลีโอไทด์ที่เป็นองค์ประกอบหลักของดีเอ็นเอ จากการศึกษาลำดับเบสของจีนที่มีรหัสในการสร้างเอนไซม์ DHFR-TS ของเชื้อมาลาเรียชนิด P. falciparum สายพันธุ์บริสุทธิ์ T9/94/RC17
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Ferro Mendez, Carolina. La malaria en Colombia, la antesala a la eliminación. Instituto Nacional de Salud, 2021. http://dx.doi.org/10.33610/01229907.2021v3n3a1.

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Introducción: la malaria es una enfermedad febril aguda, causada por parásitos del género Plasmodium spp, que puede generar desde cuadros asintomáticos y sintomáticos leves hasta la muerte. Es un problema de salud pública, en Colombia, ya que hay focos de alta transmisión. En este estudio se realizó un análisis del comportamiento del evento durante el 2019, el año de preparación en el país para la eliminación de la malaria. Materiales y métodos: se analizó la base de datos del Sistema Nacional de Vigilancia en Salud Pública – Sivigila. Se realizó una descripción de las variables demográficas y
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Liebman, Katherine. New 4-Aminoquinoline Compounds to Reverse Drug Resistance in P. falciparum Malaria, and a Survey of Early European Antimalarial Treatments. Portland State University Library, 2000. http://dx.doi.org/10.15760/etd.2112.

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