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Journal articles on the topic 'Falciparum and P'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Gangesh, Kumar Gunjan, and Kumar Jha Anand. "A Retrospective Assessment of Clinical Profile of P. Falciparum, P. Vivax and Mixed Infections of Malaria." International Journal of Current Pharmaceutical Review and Research 16, no. 2 (2024): 384–88. https://doi.org/10.5281/zenodo.12740030.

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Aim: The objective of this study was to compare the clinical profile of P. falciparum, P. vivax and mixedinfections of malaria.Methods: This retrospective observational study included malaria patients who were admitted to Department ofGeneral Medicine, Jannayak Karpoori Thakur Medical College and Hospital Madhepura,, Bihar, India for 12months. Inpatient retrieved and scrutinized on the basis of the patient’s demographic profile, clinical findings,investigations, treatment, and complications during this 12- month period.Results: The subjects consisted of 60 P. vivax and 40 P. falciparum c

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ARICAN ÇELİK, Aslı, Rıfat TAMALI, Gülruhsar YILMAZ, Pınar KARABACAK, and Mustafa Soner ÖZCAN. "A Rare Cause of Fever in ICU; Malaria." Acta Medica Nicomedia 5, no. 3 (2022): 235–37. http://dx.doi.org/10.53446/actamednicomedia.1103400.

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Sıtma, anofel cinsi sivrisineklerin insanları sokması sonucu bulaşan paraziter bir hastalıktır. Plasmodium falciparum (P Falciparum) en ölümcül tabloya yol açan türüdür, ülkemizde nadir görülür ve genellikle yurtdışı kaynaklıdır. Yoğun bakımda yüksek ateş pek çok klinik durumda karşımıza çıksa da nadir görülen bir durum olan P. Falciparuma bağlı sıtma aklımızda bulunmalıdır Bu olgu sunumunda, yurt dışı seyahat öyküsü bulunan P. Falciparum sıtma tanısı konulan hastanın yoğun bakım takip ve tedavi süreci sunulmuştur.

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Taguchi, Nao, Toshimitsu Hatabu, Haruyasu Yamaguchi, Mamoru Suzuki, Kumiko Sato, and Shigeyuki Kano. "Plasmodium falciparum: selenium-induced cytotoxicity to P. falciparum." Experimental Parasitology 106, no. 1-2 (2004): 50–55. http://dx.doi.org/10.1016/j.exppara.2004.01.005.

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Dr., Deepak Kumar Gindora, Mayank Gupta Dr., Sunil Kumar Mahavar Dr., Jai Purohit Dr., and Raman Sharma Dr. "Biochemical characteristics of Malaria patients with their association with severity of disease." International Multispeciality Journal of Health 3, no. 7 (2017): 215–22. https://doi.org/10.5281/zenodo.837945.

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<strong><em>Abstract—</em></strong><em> Malaria is one of the oldest and most widespread disease which affects more than 2400 million people, over 40% of world's population, in more than 100 countries in tropics from South America to Indian Peninsula.</em><em> This study was designed to assess the </em><em>platelet counts, haematocrit & liver enzymes (Alanine transaminase, Aspartate transaminase, Alkaline phosphatase) in patients of Plasmodium vivax & Plasmodium falciparum malaria and its association with the severity and prognosis of disease. I</em><em>n a hospital based observational

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Cserti, Christine M., and Walter H. Dzik. "The ABO blood group system and Plasmodium falciparum malaria." Blood 110, no. 7 (2007): 2250–58. http://dx.doi.org/10.1182/blood-2007-03-077602.

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In the century since the discovery of the ABO blood groups, numerous associations between ABO groups and disease have been noted. However, the selection pressures defining the ABO distributions remain uncertain. We review published information on Plasmodium falciparum infection and ABO blood groups. DNA sequence information dates the emergence and development of the group O allele to a period of evolution before human migration out of Africa, concomitant with P falciparum's activity. The current geographic distribution of group O is also consistent with a selection pressure by P falciparum in

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Zakeri, S., S. Mamaghani, A. A. Mehrizi, et al. "Molecular evidence of mixed P. vivax and P. falciparum infections in northern Islamic Republic of Iran." Eastern Mediterranean Health Journal 10, no. 3 (2004): 336–42. http://dx.doi.org/10.26719/2004.10.3.336.

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This study compared basic microscopy with molecular detection of Plasmodium species. According to thick-film microscopy, 100% of 142 malaria cases in Pars-Abad, Ardebil province, were infected with a single species, P vivax. However, nested polymerase chain reaction [PCR] detected mixed species infections of both P. vivax and P. falciparum in 7.0%. In Maz and eran province, 2/20 blood films were diagnosed with only P. falciparum and 18/20 with only P. vivax. However, nested PCR detected 17/20, 2/20 and 1/20 with P. vivax only, P. falciparum only and mixed species respectively. The unexpected p

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Goyal, Jagdish Prasad, and Aarti M. Makwana. "Comparison of Clinical Profile between P. vivax and P. falciparum Malaria in Children: A Tertiary Care Centre Perspective from India." Malaria Research and Treatment 2014 (April 9, 2014): 1–4. http://dx.doi.org/10.1155/2014/132672.

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Background. Malaria is a one of the leading causes of morbidity and mortality in tropical countries. Plasmodium vivax (P. vivax) is usually thought to be causing benign malaria with low incidence of complications as compared to Plasmodium falciparum (P. falciparum). Methods. This retrospective observational study included malaria patients who were admitted to K.T. Children Hospital and P.D.U. Government Medical College, Rajkot, a tertiary care teaching hospital, Gujarat, western India, during the period January 2012 to December 2012. Inclusion criteria were patients in whom either P. falciparu

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Dr., Tehmina Hayat Dr. Arshia Maqbool Dr. Muhammad Adnan Akbar. "PREVALANCE OF MALARIA IN EASTERN AREAS OF BALUCHISTAN AT BORDERS OF OTHER PROVINCES." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 05 (2018): 4395–400. https://doi.org/10.5281/zenodo.1254447.

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Objective:<em> The objective of the study was to decide the occurrences of parasites causing malaria in far flung human populations of Balochistan. </em> Methodology:<em> A large group of 3340 subjects was examined for malarial parasites by testing the blood samples during the timeframe of 2 years i.e. July 2015 to June 2017.</em> Results:<em> The laboratory tests revealed that 1095 (32.78%) cases were diagnosed with malaria out of total suspected sample of 3340. Among 1095 infected cases, 579 were due to </em>Plasmodium falciparum<em> infection and 516 cases were infected with </em>Plasmodium

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Dr, Fatima Altaf Dr. Namra Tufail Dr. Shifa Batool. "PREVALANCE OF MALARIA IN EASTERN AREAS OF BALUCHISTAN AT BORDERS OF OTHER PROVINCES." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 05 (2018): 4593–98. https://doi.org/10.5281/zenodo.1257636.

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Objective:<em> The objective of the study was to decide the occurrences of parasites causing malaria in far flung human populations of Balochistan. </em> Methodology:<em> A large group of 3340 subjects was examined for malarial parasites by testing the blood samples during the timeframe of 2 years i.e. July 2015 to June 2017.</em> Results:<em> The laboratory tests revealed that 1095 (32.78%) cases were diagnosed with malaria out of total suspected sample of 3340. Among 1095 infected cases, 579 were due to </em>Plasmodium falciparum<em> infection and 516 cases were infected with </em>Plasmodium

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Payal, Jivani, Panchal Bijal, Parmar Sudha, Mehta Neeta, Savaliya Chirag, and Sorani Ashvin. "A COMPARATIVE STUDY OF EFFECT OF P. FALCIPARUM AND P. VIVAX MALARIA ON PLATELET COUNT." International Journal of Basic & Applied Physiology 3, no. 1 (2014): 243–47. https://doi.org/10.5281/zenodo.4486391.

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<strong>Background & objectives</strong>: Malaria is a big menace in India affecting almost 24 million peoples and causing 2.4 deaths per 1, 00,000 populations annually. Malaria affects almost all the organs of body but varieties of typical hematological alterations have been reported. Present study aims to evaluate impact of malaria on platelet count and species specific changes if any. <strong>Methods:</strong> This study was carried out in Deendayal Upadhyay Govt. Medical College and Hospital, Rajkot 100 known hospitalized cases of malaria. All the hematological parameters including pla

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Umar, Khairuddin Zainuddin, Yuri P.Utami, and Muhammad A.Y. Ardi. "Antimalarial Activity of Ethanol Extract of Sampare Leaves (Glochidion sp var. Biak) Against Plasmodium falciparum In Vitro." Indonesian Journal of Pharmaceutical Science and Technology 10, no. 1 (2023): 10. http://dx.doi.org/10.24198/ijpst.v10i1.29477.

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Malaria is one of the health problems in the world and in Indonesia. This disease is caused by theprotozoan parasite, the genus Plasmodium. Plasmodium falciparum is the most important parasiticdisease with high morbidity and mortality in the world and tropical countries such as Indonesia inparticular. This study aims to determine the activity of sampare leaf extract in inhibiting the growth ofthe FCR-3 strain of the P. falciparum parasite which causes malaria. Sampare leaves were extracted bymaceration method using 70% ethanol. Extract the results extraction were tested against P. falciparumby

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Platon, Lucien, Jun Cao, and Didier Ménard. "Compensating P. falciparum artemisinin resistance." Cell Host & Microbe 29, no. 12 (2021): 1732–34. http://dx.doi.org/10.1016/j.chom.2021.11.007.

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Casalino, E., C. Choquet, and B. Doumenc. "Paludisme d’importation à P. falciparum." EMC - Médecine d 'urgence 7, no. 2 (2012): 1–11. http://dx.doi.org/10.1016/s1959-5182(12)56606-7.

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Ende, Jef, Rudi Paep, and Jan Clerinx. "Suboptimal Prophylaxis for P. falciparum." Journal of Travel Medicine 6, no. 4 (1999): 262–63. http://dx.doi.org/10.1111/j.1708-8305.1999.tb00531.x.

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Casalino, E., C. Choquet, and B. Doumenc. "Paludisme d’importation à P. falciparum." EMC - Urgence 25, no. 4 (2012): 1–11. https://doi.org/10.1016/s1241-8234(12)62817-x.

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Wångdahl, Andreas, Katja Wyss, Dashti Saduddin, et al. "Severity of Plasmodium falciparum and Non-falciparum Malaria in Travelers and Migrants: A Nationwide Observational Study Over 2 Decades in Sweden." Journal of Infectious Diseases 220, no. 8 (2019): 1335–45. http://dx.doi.org/10.1093/infdis/jiz292.

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Abstract Background The aim was to assess factors affecting disease severity in imported P. falciparum and non-falciparum malaria. Methods We reviewed medical records from 2793/3260 (85.7%) of all episodes notified in Sweden between 1995 and 2015 and performed multivariable logistic regression. Results Severe malaria according to WHO 2015 criteria was found in P. falciparum (9.4%), P. vivax (7.7%), P. ovale (5.3%), P. malariae (3.3%), and mixed P. falciparum episodes (21.1%). Factors associated with severe P. falciparum malaria were age <5 years and >40 years, origin in nonendemic countr

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M., Rukmini Ramya, and Rajya Lakshmi M. "A prospective comparative study of clinical profile and severity of plasmodium falciparum and plasmodium vivax in coastal Andhra Pradesh, India." International Journal of Advances in Medicine 5, no. 5 (2018): 1240. http://dx.doi.org/10.18203/2349-3933.ijam20183901.

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Background: Plasmodium falciparum (P. falciparum) causes vital organ dysfunction. The manifestation of severe form of falciparum malaria includes cerebral malaria, acidosis, severe anaemia, renal failure, hypotension, shock, disseminated intravascular coagulation and convulsion. Death rate used to be high. But vivax malaria is not presented in severe form and there is tendency of recurrence. Present study has been designed to compare clinical profile and severity of P. falciparum and Plasmodium vivax (P. vivax) malaria in coastal district of Andhra Pradesh.Methods: Present study is a prospecti

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Merrick, Catherine J. "Plasmodium falciparum." Emerging Topics in Life Sciences 1, no. 6 (2017): 517–23. http://dx.doi.org/10.1042/etls20170099.

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Plasmodium falciparum is a protozoan parasite that causes the most severe form of human malaria. Five other Plasmodium species can also infect humans — P. vivax, P. malariae, P. ovale curtisi, P. ovale wallikeri and P. knowlesi — but P. falciparum is the most prevalent Plasmodium species in the African region, where 90% of all malaria occurs, and it is this species that causes the great majority of malaria deaths. These were reported by the WHO at 438 000 in 2015 from an estimated 214 million cases; importantly, however, figures for the global burden of malaria tend to have wide margins of err

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Sariyanto, Iwan. "Aktivitas SGOT Dan SGPT Pada Penderita Malaria Falciparum Dan Malaria Vivax Di Puskesmas Hanura Kecamatan Teluk Pandan Kabupaten Pesawaran." Jurnal Analis Kesehatan 7, no. 1 (2018): 666. http://dx.doi.org/10.26630/jak.v7i1.913.

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<p>Penyakit Malaria bersifat endemik di daerah tropis dan subtropis. <em>Plasmodium falciparum</em> dan <em>plasmodium vivax</em> merupakan penyebab malaria terbanyak di Indonesia. <em>Plasmodium falciparum</em> menginvasi sel darah merah hingga mencapai 50%. Pembesaran hati lebih sering ditemukan dari pada pembesaran limpa. Sedangkan pada <em>plasmodium vivax </em> menginveksi retikulosit, sehingga parasitemia biasanya terbatas sekitar 2-5%,<em> </em>dapat terjadi relaps, karena maturasi hipnozoit yang tertinggal dalam hati. &l

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Alam, Mohammad Tauqeer, Hema Bora, Praveen K. Bharti, et al. "Similar Trends of Pyrimethamine Resistance-Associated Mutations in Plasmodium vivax and P. falciparum." Antimicrobial Agents and Chemotherapy 51, no. 3 (2006): 857–63. http://dx.doi.org/10.1128/aac.01200-06.

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ABSTRACT The antifolate drugs sulfadoxine and pyrimethamine are commonly used to treat Plasmodium falciparum malaria. However, they can also affect the Plasmodium vivax parasite if it coexists with P. falciparum, as both species have common drug targets. Resistance to the antifolate drugs arises due to point mutations in the target enzymes of the respective parasite. To assess the cross-species impact of antifolate drug treatment, we describe here the dihydrofolate reductase (DHFR) mutations among field isolates of P. vivax and P. falciparum. The overall DHFR mutation rate for P. vivax was low

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Aich, Tarkeswar. "P. falciparum Malaria induced Renal impairment." Journal of Medical Research 5, no. 6 (2019): 220–23. http://dx.doi.org/10.31254/jmr.2019.5605.

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Introduction: The involvement of the kidney in falciparum malaria has been known for decades. In 1944, Spitz observed acute renal failure due to falciparum infection in soldiers during World War II. This observation was later supported by other workers who detected oliguria developing in patients with black water fever. The initial clinical pattern is that of reversible renal dysfunction or pre-renal azotemia, which rapidly progresses to acute tubular necrosis if treatment is not started early. Patients with malaria induced renal failure are hypercatabolic with blood urea and serum creatinine

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Njila, HL, JE Idoko, A. Ombugadu, and H. Zakari. "Hemoglobin genotype variants and Plasmodium Falciparum malaria in children receiving postpartum care at Faith Alive Foundation Jos, Plateau State, Nigeria." Archives of Community Medicine and Public Health 8, no. 4 (2022): 147–51. http://dx.doi.org/10.17352/2455-5479.000191.

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More and more data are showing a link between hemoglobin genotypes and Plasmodium falciparum malaria. In order to establish the prevalence of hemoglobin genotype variants and their association with P. falciparum malaria in children receiving postpartum care at Faith Alive Foundation Jos, Plateau State, we study the distribution of these variants. From each sample, thick and thin blood films were created, and hemoglobin genotypes were determined using electrophoresis. Out of 172 samples examined, 131 (76.16%) were infected with P. falciparum malaria while 41 (23.84%) were not infected. There wa

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Mansouri, Reza, Mohammad Ali-Hassanzadeh, Reza Shafiei, et al. "The use of proteomics for the identification of promising vaccine and diagnostic biomarkers in Plasmodium falciparum." Parasitology 147, no. 12 (2020): 1255–62. http://dx.doi.org/10.1017/s003118202000102x.

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AbstractPlasmodium falciparum is the main cause of severe malaria in humans that can lead to death. There is growing evidence of drug-resistance in P. falciparum treatment, and the design of effective vaccines remains an ongoing strategy to control the disease. On the other hand, the recognition of specific diagnostic markers for P. falciparum can accelerate the diagnosis of this parasite in the early stages of infection. Therefore, the identification of novel antigenic proteins especially by proteomic tools is urgent for vaccination and diagnosis of P. falciparum. The proteome diversity of th

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Christian, Dayena J., Rajesh H. Vekariya, Kinjal D. Patel, et al. "Molecular Docking and QSAR Study of Chalcone and Pyrimidine Derivatives as Potent Anti-Malarial Agents against <i>Plasmodium falciparum</i>." International Letters of Chemistry, Physics and Astronomy 85 (December 24, 2020): 23–34. http://dx.doi.org/10.56431/p-75shdg.

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A data set of chalcone and pyrimidine derivatives with anti-malarial activity against Plasmodium falciparum was employed in investigating the quantitative structure-activity relationship (QSAR). Molecular docking study was performed for plasmodium falciparum dihydrofolate reductase (PfDHFR-TS). Genetic function approximation (GFA) technique was used to identify the descriptors that have influence on anti-malarial activity. The most influencing molecular descriptors identified include thermodynamics, structural and physical descriptors. Generated model was found to be good based on correlation

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Gomes, Luciano T., Mauro S. Tada, Tony H. Katsuragawa, et al. "Low sensitivity of malaria rapid diagnostic tests stored at room temperature in the Brazilian Amazon Region." Journal of Infection in Developing Countries 7, no. 03 (2013): 243–52. http://dx.doi.org/10.3855/jidc.2564.

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Introduction: In remote areas of the Amazon Region, diagnosis of malaria by microscopy is practically impossible. This study aimed to evaluate the performance of two rapid diagnostic tests (RDTs) targeting different malaria antigens stored at room temperature in the Brazilian Amazon Region. Methodology: Performance of the OptiMal Pf/Pan test and ICT-Now Pf/Pan test was analyzed retrospectively in 1,627 and 1,602 blood samples, respectively. Tests were performed over a 15-month period. Kits were stored at room temperature in five community health centres located in the Brazilian Amazon Region.

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Tan, Nie, Yuemeng Zhao, Yan Ding, et al. "Potential role of CI-679 against artemisinin-resistant <i>Plasmodium falciparum</i>." Tropical Journal of Pharmaceutical Research 23, no. 1 (2024): 85–90. http://dx.doi.org/10.4314/tjpr.v23i1.11.

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Purpose: To investigate the role of nitroquine (CI-679) against artemisinin-resistant Plasmodium falciparum (P. falciparum) C580Y strain. Methods: Antimalarial activity of CI-679 against blood stages in Plasmodium yoelii (P. yoelii) - infected BALB/c mice model was first identified. Thereafter, in vitro assays were performed to investigate the inhibitory activity against blood stages of artemisinin-sensitive P. falciparum 3D7 strain. Finally, the potential effect of CI-679 was also investigated on artemisinin-resistant P. falciparum, which was constructed by introducing C580Y mutation in

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Kumari, Preeti Ranjana, Kumar Sujit, and Kumar Aravind. "Spectrum of Clinical Manifestations in Patients Diagnosed of Malaria and to Compare the Severity of P. Vivax and P. Falciparum Malaria." International Journal of Pharmaceutical and Clinical Research 14, no. 6 (2022): 423–27. https://doi.org/10.5281/zenodo.13625821.

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<strong>Aim: </strong>The aim of our study was to find out the spectrum of clinical manifestations, infecting species, age distribution and mortality in admitted patients of malaria in our hospital and to compare the clinical profile with severity of P.vivax and P. falciparum malaria. <strong>Material & Method: </strong>The study was carried out on 150 patients admitted during the period of seven months in the hospital. It was analytical cross-sectional study, which was done in the Vardhman Institute of Medical sciences, Pawapuri, Nalanda, Bihar, India. <strong>Results:

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Nkansah, Charles, Simon Bannison Bani, Kofi Mensah, et al. "Serum anti-erythropoietin antibodies among pregnant women with Plasmodium falciparum malaria and anaemia: A case-control study in northern Ghana." PLOS ONE 18, no. 3 (2023): e0283427. http://dx.doi.org/10.1371/journal.pone.0283427.

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Background Anaemia in pregnancy is common in underdeveloped countries, and malaria remains the predominant cause of the condition in Ghana. Anti-erythropoietin (anti-EPO) antibody production may be implicated in the pathogenesis of Plasmodium falciparum malaria-related anaemia in pregnancy. This study ascertained the prevalence of anti-EPO antibody production and evaluated the antibodies’ relationship with Plasmodium falciparum malaria and malaria-related anaemia in pregnancy. Methods This hospital-based case-control study recruited a total of 85 pregnant women (55 with Plasmodium falciparum m

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Muhammad TH, Inabo HI, Machido DA та Ameh JB. "Interferon alpha (IFN-ɑ) among Human Immunodeficiency Virus (HIV) patients exposed to Plasmodium falciparum infection in selected Hospitals in Niger State, Nigeria". World Journal of Biology Pharmacy and Health Sciences 14, № 3 (2023): 026–32. http://dx.doi.org/10.30574/wjbphs.2023.13.3.0094.

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Both Human Immunodeficiency Virus (HIV) and Plasmodium falciparum (P. falciparum) infection are associated with production of several cytokines such as type I Interferons which may be beneficial to the host during acute infection. The plasma level of type I interferons could vary among HIV patients co-infected with P. falciparum. This study therefore, aims to quantify the level of IFN-α, a type 1 interferon, among HIV patients exposed to P. falciparum infection in selected Hospitals in Niger State, Nigeria. This was a cross-sectional study. Blood samples were collected from 300 HIV patients fo

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Dashrath, Kumar Singh, Mudang Umbing, and Jha Vinayanand. "A Prospective Observational Study on Acute Kidney Injury in Patients of Falciparum and Vivax Malaria." International Journal of Pharmaceutical and Clinical Research 16, no. 12 (2024): 931–36. https://doi.org/10.5281/zenodo.14597884.

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<strong>Background:</strong> Although Plasmodium falciparum malaria is known to cause acute kidney injury (AKI), Plasmodium vivax malaria is now more often the cause of this outcome. Several recent studies have shown that P. vivax malaria also causes AKI. Examining the demographic profile, clinical traits, mortality indicators, need for dialysis, and overall outcome of patients with P. falciparum and P. vivax malaria is the aim of this study. <strong>Methods:</strong> In the Department of Medicine at Darbhanga Medical College and Hospital, Laheriasarai, Bihar, a prospective obse

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Mude, Abdirasak S. A., and Abd Elhadi M. Agena. "Assessing the distribution of ABO blood groups and how they are linked to Plasmodium falciparum malaria in Yashiid District, Somalia." Egyptian Journal of Haematology 49, no. 3 (2024): 272–76. https://doi.org/10.4103/ejh.ejh_84_23.

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Background Evaluation of the ABO blood group distribution and its connection with Plasmodium falciparum infection is crucial for transfusion therapy and malaria prevention. The goal of this study was to assess the distribution of ABO blood groups, and how they are linked to Plasmodium falciparum malaria in Yashiid District, Southern Somalia. Method From January to September 2022, a hospital-based cross-sectional study was conducted. For data collection, a structured questionnaire was used. After each participant had given their informed consent to take part in the study, a blood sample was tak

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Dao, Francois, Laurent Dembele, Backoroba Diarra, et al. "The Prevalence of Human Plasmodium Species during Peak Transmission Seasons from 2016 to 2021 in the Rural Commune of Ntjiba, Mali." Tropical Medicine and Infectious Disease 8, no. 9 (2023): 438. http://dx.doi.org/10.3390/tropicalmed8090438.

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Up-to-date knowledge of key epidemiological aspects of each Plasmodium species is necessary for making informed decisions on targeted interventions and control strategies to eliminate each of them. This study aims to describe the epidemiology of plasmodial species in Mali, where malaria is hyperendemic and seasonal. Data reports collected during high-transmission season over six consecutive years were analyzed to summarize malaria epidemiology. Malaria species and density were from blood smear microscopy. Data from 6870 symptomatic and 1740 asymptomatic participants were analyzed. The median a

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&NA;. "Antiretrovirals affect host-P. falciparum interactions." Inpharma Weekly &NA;, no. 1407 (2003): 19. http://dx.doi.org/10.2165/00128413-200314070-00044.

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&NA;. "Weekly tafenoquine prevents P. falciparum malaria." Inpharma Weekly &NA;, no. 1385 (2003): 6. http://dx.doi.org/10.2165/00128413-200313850-00017.

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Eridani, Sandro. "HbS Protection from P. falciparum Infection." British Journal of Medicine and Medical Research 3, no. 4 (2013): 790–801. http://dx.doi.org/10.9734/bjmmr/2013/2427.

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Martínez Rodríguez, José Enrique, Juan Pablo Horcajada Gallego, Joaquín Gascón Brustenga, and Manuel Corachán Cuyas. "Paludismo por P. falciparum y exanguinotransfusión." Medicina Clínica 114, no. 1 (2000): 37–38. http://dx.doi.org/10.1016/s0025-7753(00)71180-8.

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M, J. M. "Paludisme : 2 molécules éradiquent P. falciparum." Revue Francophone des Laboratoires 2013, no. 452 (2013): 14. http://dx.doi.org/10.1016/s1773-035x(13)72013-6.

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Newton, Paul N., Georg Michelson, Ronatrai Ruangveerayuth, and Nicholas J. White. "Retinal haemorrhage in P falciparum malaria." Lancet 360, no. 9332 (2002): 515. http://dx.doi.org/10.1016/s0140-6736(02)09739-8.

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Simon, F., D. Jeannel, I. Nicoulet, E. Rusch, J. P. Coulaud, and M. Gentilini. "Les acces graves a P. falciparum." Médecine et Maladies Infectieuses 18, no. 8-9 (1988): 360–66. http://dx.doi.org/10.1016/s0399-077x(88)80179-3.

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Casalino, E., C. Choquet, and B. Doumenc. "Malaria di importazione da P. falciparum." EMC - Urgenze 17, no. 1 (2013): 1–11. http://dx.doi.org/10.1016/s1286-9341(12)63934-9.

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Roberts, DJ, AG Craig, AR Berendt, et al. "Clonal Antigenic Variation in P. Falciparum." Clinical Science 85, s29 (1993): 30P—31P. http://dx.doi.org/10.1042/cs085030pc.

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Branco, Ana, and José Melo-Cristino. "Extreme parasitemia in P falciparum malaria." Blood 132, no. 8 (2018): 868. http://dx.doi.org/10.1182/blood-2018-07-861880.

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Alves-Rosa, María Fernanda, Nicole M. Tayler, Doriana Dorta, Lorena M. Coronado, and Carmenza Spadafora. "P. falciparum Invasion and Erythrocyte Aging." Cells 13, no. 4 (2024): 334. http://dx.doi.org/10.3390/cells13040334.

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Plasmodium parasites need to find red blood cells (RBCs) that, on the one hand, expose receptors for the pathogen ligands and, on the other hand, maintain the right geometry to facilitate merozoite attachment and entry into the red blood cell. Both characteristics change with the maturation of erythrocytes. Some Plasmodia prefer younger vs. older erythrocytes. How does the life evolution of the RBC affect the invasion of the parasite? What happens when the RBC ages? In this review, we present what is known up until now.

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Bhowmick, Ipsita Pal, Tulika Nirmolia, Apoorva Pandey, et al. "Dry Post Wintertime Mass Surveillance Unearths a Huge Burden of P. vivax, and Mixed Infection with P. vivax P. falciparum, a Threat to Malaria Elimination, in Dhalai, Tripura, India." Pathogens 10, no. 10 (2021): 1259. http://dx.doi.org/10.3390/pathogens10101259.

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With India aiming to achieve malaria elimination by 2030, several strategies have been put in place. With that aim, mass surveillance is now being conducted in some malaria-endemic pockets. As dry season mass surveillance has been shown to have its importance in targeting the reservoir, a study was undertaken to assess the parasite load by a sensitive molecular method during one of the mass surveys conducted in the dry winter period. It was executed in two malaria-endemic villages of Dhalai District, Tripura, in northeast India, also reported as P. falciparum predominated area. The present stu

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Mosso, Justhina Ensly, and Chrismerry Song. "Distribusi prevalensi infeksi Plasmodium serta gambaran kepadatan parasit dan jumlah limfosit absolut pada penderita malaria di RSUD Kabupaten Manokwari periode Januari – Maret 2019." Tarumanagara Medical Journal 2, no. 2 (2020): 320–30. http://dx.doi.org/10.24912/tmj.v3i1.9735.

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Malaria menjadi perhatian global karena tingginya angka mortalitas dan morbiditas, terutama pada kelompok berisiko tinggi di daerah endemis, termasuk di Manokwari, Papua Barat. Tujuan penelitian ini adalah untuk mendeskripsikan prevalensi infeksi Plasmodium serta kepadatan parasit dan jumlah limfosit pada penderita malaria di RSUD Manokwari. Penelitian deskriptif cross sectional ini terdiri dari data 100 sampel yang diperoleh dari rekam medis pasien periode Januari-Maret 2019. Dari 100 sampel penelitian didapatkan bahwa 52 (52%) pasien terinfeksi P. falciparum dan 42 (42%) pasien lainnya terin

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Nyamngee, A., H. A. Edogun, M. K. Sulaiman, R. T. Ikpe, and A. A. Njan. "Genetic Diversity of Plasmodium falciparum Based on Merozoite Surface Proteins 1 and 2 Genes." African Journal of Biomedical Research 25, no. 2 (2022): 163–67. http://dx.doi.org/10.4314/ajbr.v25i2.7.

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Genetic diversity of Plasmodium falciparum is an important feature that makes the parasite a successful pathogen and is a risk factor for generating mutant variants involved in pathogenicity, drug resistance and immune evasion. A study was designed to determine the diversity of P. falciparum isolates based on merozoite surface protein 1 and 2, determine the predominant circulating allelic families and multiplicity of infection in Nigeria. The diagnosis was based on finding the characteristic asexual stage of the parasite in Giemsa-stained blood smears under a compound microscope. The Deoxyribo

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Mulyana, Fathoni Ega, Stephanus Satria Wira Waskitha, Deni Pranowo, Melati Khairuddean, and Tutik Dwi Wahyumingsih. "Synthesis of chalcone derivatives with methoxybenzene and pyridine moieties as potential antimalarial agents." Pharmacia 70, no. (4) (2023): 1305–13. https://doi.org/10.3897/pharmacia.70.e107406.

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Malaria remains an endemic disease in tropical regions, urgently needed the search for effective antimalarial agents due to resistance against existing drugs. This study investigated the potential antimalarial activity of pyridine-based chalcone derivatives against <i>P. falciparum</i> 3D7 and FCR3 strains. The chalcones were synthesized through a one-pot method using various pyridine carbaldehyde, resulting in yields ranging from 53.74 to 86.37%, and all products were characterized using FTIR, GC-MS, and NMR spectroscopies. Among the six chalcones tested, chalcone A [1-(2-methoxyphenyl)-3-(py

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Shashi, Kiran Shankarappa, B. Udaykumar, S. Kulkarni Spurti, and B. Ganashree. "Comparative Study of Clinicoetiological Profile of Cerebral Malaria in Hospitalized Children Due to P. Falciparum and P. Vivax." International Journal of Pharmaceutical and Clinical Research 16, no. 11 (2024): 650–54. https://doi.org/10.5281/zenodo.14246542.

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<strong>Background & Methods:</strong> The aim of the study is to comparative study of clinicoetiological profile of cerebral malaria in hospitalized children due to p. falciparum and p. vivax. All those children who were previously neurologically normal, of age 6  months  – 18 years  and presented with a history of fever with generalised convulsion and   loss of conscious for more than 30 min, underwent a peripheral blood smear examination and rapid diagnostic test for malarial parasite. <strong>Results:</strong> Out of 41 children infected wi

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Sun, He, Bo-Chao Liu, Long-Fei He, Chao-Jiang Xiao, Bei Jiang, and Lei Shen. "Dobinin K Displays Antiplasmodial Activity through Disruption of Plasmodium falciparum Mitochondria and Generation of Reactive Oxygen Species." Molecules 29, no. 19 (2024): 4759. http://dx.doi.org/10.3390/molecules29194759.

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Dobinin K is a novel eudesmane sesquiterpenoids compound isolated from the root of Dobinea delavayi and displays potential antiplasmodial activity in vivo. Here, we evaluate the antiplasmodial activity of dobinin K in vitro and study its acting mechanism. The antiplasmodial activity of dobinin K in vitro was evaluated by concentration-, time-dependent, and stage-specific parasite inhibition assay. The potential target of dobinin K on Plasmodium falciparum was predicted by transcriptome analysis. Apoptosis of P. falciparum was detected by Giemsa, Hoechst 33258, and TUNEL staining assay. The rea

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Amari, Mutiara Rahmah, Hesti Lina Wiraswati, Nisa Fauziah, and Ilma Fauziah Ma’ruf. "Antimalarial Effect of Doxorubicin on Plasmodium Falciparum: An in Vitro Study in FCR-3 Strain." Biomedical and Pharmacology Journal 15, no. 1 (2022): 313–20. http://dx.doi.org/10.13005/bpj/2369.

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Plasmodium falciparum is the most common species of Plasmodium that causes malaria in Southeast Asia. Artemisinin, a drug with the mechanism of action by inducing oxidative stress in infected red blood cells (RBC) is currently used as the main therapy for malaria, after resistance to chloroquine has been found. However, evidence of artemisinin resistance was discovered in several regions in Southeast Asia. Therefore, a research is required to prove the existence of other drugs that have anti-malaria effects. A drug candidate, doxorubicin also can induce the formation of oxidative stress inside

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