Academic literature on the topic 'Familial aggregation'

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Journal articles on the topic "Familial aggregation"

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Houwing-Duistermaat, Jeanine J., Bert H. F. Derkx, Frits R. Rosendaal, and Hans C. van Houwelingen. "Testing Familial Aggregation." Biometrics 51, no. 4 (1995): 1292. http://dx.doi.org/10.2307/2533260.

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SUSSER, EZRA, and MERVYN SUSSER. "FAMILIAL AGGREGATION STUDIES." American Journal of Epidemiology 129, no. 1 (1989): 23–30. http://dx.doi.org/10.1093/oxfordjournals.aje.a115119.

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Guo, S. W. "Familial Aggregation of Environmental Risk Factors and Familial Aggregation of Disease." American Journal of Epidemiology 151, no. 11 (2000): 1121–31. http://dx.doi.org/10.1093/oxfordjournals.aje.a010156.

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BOLTON, DEREK, FRÜHLING RIJSDIJK, THOMAS G. O'CONNOR, SEAN PERRIN, and THALIA C. ELEY. "Obsessive–compulsive disorder, tics and anxiety in 6-year-old twins." Psychological Medicine 37, no. 1 (2006): 39–48. http://dx.doi.org/10.1017/s0033291706008816.

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Background. Previous reports of genetic influences on obsessive–compulsive disorder (OCD) symptoms have suggested moderate heritability. Family history studies of co-morbidity have found familial aggregation with tics, especially for early-onset OCD, and familial aggregation with anxiety disorders.Method. Heritability of OCD and familial aggregation of OCD, tics and anxiety disorders were investigated in a community sample of 6-year-old twins using a two-phase design in which 4662 twin pairs were sampled and 854 pairs were assessed in the second phase by maternal-informant diagnostic interview
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RYBICKI, BENJAMIN A, MICHAEL C IANNUZZI, MARGARET M FREDERICK, et al. "Familial Aggregation of Sarcoidosis." American Journal of Respiratory and Critical Care Medicine 164, no. 11 (2001): 2085–91. http://dx.doi.org/10.1164/ajrccm.164.11.2106001.

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Wing, Yun-Kwok, Lei Chen, Siu-Ping Lam, et al. "Familial aggregation of narcolepsy." Sleep Medicine 12, no. 10 (2011): 947–51. http://dx.doi.org/10.1016/j.sleep.2011.05.007.

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Heun, Reinhard, and Sandra Hein. "Familial aggregation of depression, but no familial aggregation of individual depressive symptoms." European Psychiatry 22, no. 1 (2007): 16–21. http://dx.doi.org/10.1016/j.eurpsy.2006.09.001.

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AbstractBackgroundFamilial aggregation of major depression might indicate a genetic liability for the disorder. The complete disorder or, alternatively, only some individual symptoms might be inherited. Under the latter condition, an increased frequency of inherited symptoms might consecutively increase the likelihood to reach the threshold for depression in relatives and, thus, might cause the familial aggregation of depression. Up to now, no study investigated the possibility of a relationship between individual depressive symptoms and the familial aggregation of depression.MethodsThe famili
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Kendler, Kenneth S. "Familial risk factors and the familial aggregation of psychiatric disorders." Psychological Medicine 20, no. 2 (1990): 311–19. http://dx.doi.org/10.1017/s0033291700017621.

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SynopsisAll major psychiatric disorders aggregate in families. For most disorders, both genes and environmental factors play an important role in this aggregation. While recent work has tended to concentrate on the importance of genetic factors, this report focuses on the potential importance of environmental risk factors which themselves aggregate in families. In particular, this article examines how much of the familial aggregation of a psychiatric disorder may result from the familial aggregation of a risk factor. The model is illustrated and then applied to putative familial risk factors f
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Shakhtarina, Svetlana Vasilevna, A. A. Danilenko, and N. A. Falaleeva. "Familial Aggregation in Hodgkin’s Lymphoma." Clinical oncohematology 14, no. 2 (2021): 193–97. http://dx.doi.org/10.21320/2500-2139-2021-14-2-193-197.

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Page, Jessica M., Tsegaselassie Workalemahu, Nathan R. Blue, et al. "1036 Familial aggregation of stillbirth." American Journal of Obstetrics and Gynecology 224, no. 2 (2021): S642—S643. http://dx.doi.org/10.1016/j.ajog.2020.12.1061.

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Dissertations / Theses on the topic "Familial aggregation"

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Tahir, Hassaan. "Familial Aggregation of Severe Preeclampsia." Thesis, Linköpings universitet, Statistik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-73266.

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It has been proved from several studies that the genetic influence has been the most significant factor for having preeclampsia (PE). Still there are many uncertainties about origin and magnitude of the genetic effects as no specific inheritance patterns have been established. In this study, heritage risk of PE is in both the woman’s family and her partner’s family to her risk of PE is examined, along women and men own history with same and different partners. Moreover it is also examined whether timing of onset of PE is also has any impact on familial clustering of PE. Here, we used the popul
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Pappas, Sylvie Rachelle. "The familial aggregation of agoraphobia." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0017/MQ47079.pdf.

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Beaujeux, Timothy Paul. "Protein aggregation in a mouse model of familial motor neurone disease." Thesis, University of Sheffield, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427349.

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Seeley, John Robert. "Comorbidity between conduct disorder and major depression : phenomenology, correlates, course, and familial aggregation /." view abstract or download file of text, 2001. http://wwwlib.umi.com/cr/uoregon/fullcit?p3035576.

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Thesis (Ph. D.)--University of Oregon, 2001.<br>"Based on data collected from the Oregon Adolescent Depresssion Project (OADP)."--Abstract. Typescript. Includes vita and abstract. Includes bibliographical references (leaves 73-84). Also available for download via the World Wide Web; free to University of Oregon users.
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Brauer, Paula Mae. "Familial aggregation of diabetes, hypertension and cardiovascular conditions in a case-control study of colorectal neoplasia." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0023/NQ49836.pdf.

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Tisler, Andras. "Analysis of the familial aggregation of hypertension among patients with different types of kidney stone disease." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0022/MQ40818.pdf.

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Räsänen, Maija. "Familial aggregation and risk factors for asthma and hay fever among Finnish adolescent twins : a twin family study." Helsinki : University of Helsinki, 2000. http://ethesis.helsinki.fi/julkaisut/laa/kansa/vk/rasanen/.

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Andersson, Karin, M. Pokrzywa, Ingrid Dacklin, and Erik Lundgren. "Inhibition of TTR aggregation-induced cell death : a new role for serum amyloid P component." Umeå universitet, Institutionen för molekylärbiologi (Medicinska fakulteten), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-65622.

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BACKGROUND: Serum amyloid P component (SAP) is a glycoprotein that is universally found associated with different types of amyloid deposits. It has been suggested that it stabilizes amyloid fibrils and therefore protects them from proteolytic degradation. METHODOLOGY/PRINCIPAL FINDINGS: In this paper, we show that SAP binds not only to mature amyloid fibrils but also to early aggregates of amyloidogenic mutants of the plasma protein transthyretin (TTR). It does not inhibit fibril formation of TTR mutants, which spontaneously form amyloid in vitro at physiological pH. We found that SAP prevents
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de, Zwaan Sally Elizabeth. "The Genetics of Basal Cell Carcinoma of the Skin." Thesis, The University of Sydney, 2008. http://hdl.handle.net/2123/3878.

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BCC is the commonest cancer in European-derived populations and Australia has the highest recorded incidence in the world, creating enormous individual and societal cost in management of this disease. The incidence of this cancer has been increasing internationally, with evidence of a 1 to 2% rise in incidence in Australia per year over the last two decades. The main four epidemiological risk factors for the development of BCC are ultraviolet radiation (UVR) exposure, increasing age, male sex, and inability to tan. The pattern and timing of UVR exposure is important to BCC risk, with childhood
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de, Zwaan Sally Elizabeth. "The Genetics of Basal Cell Carcinoma of the Skin." University of Sydney, 2008. http://hdl.handle.net/2123/3878.

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Doctor of Philosophy(PhD)<br>BCC is the commonest cancer in European-derived populations and Australia has the highest recorded incidence in the world, creating enormous individual and societal cost in management of this disease. The incidence of this cancer has been increasing internationally, with evidence of a 1 to 2% rise in incidence in Australia per year over the last two decades. The main four epidemiological risk factors for the development of BCC are ultraviolet radiation (UVR) exposure, increasing age, male sex, and inability to tan. The pattern and timing of UVR exposure is importan
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Books on the topic "Familial aggregation"

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Koch-Henriksen, Nils. An epidemiological study of multiple sclerosis: Familial aggregation, social determinants, and exogenic factors. Munksgaard, 1989.

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Tisler, Andras. Analysis of the familial aggregation of hypertension among patients with different types of kidney stone disease. National Library of Canada, 1998.

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Brauer, Paula Mae. Familial aggregation of diabetes, hypertension and cardiovascular conditions in a case-control study of colorectal neoplasia. 2000.

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Mittal, Sajjan. Amyloidosis. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0181.

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Amyloidosis is a multisystem disease caused by the extracellular deposition of insoluble abnormal fibrils that injure tissues and organs. The fibrils are formed by the aggregation of misfolded, normally soluble proteins. Systemic amyloid light-chain (AL) amyloidosis (primary amyloidosis) is the commonest type of amyloidosis in the developed world, accounting for 80% of cases. The remainder are due to AA amyloidosis (secondary or reactive amyloidosis), familial amyloidosis, or other rare types of amyloidosis. The most common clinical features at diagnosis are nephrotic syndrome, heart failure (
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Otowa, Takeshi, Roxann Roberson-Nay, Mandakh Bekhbat, Gretchen N. Neigh, and John M. Hettema. Genetics of Anxiety Disorders. Edited by Dennis S. Charney, Eric J. Nestler, Pamela Sklar, and Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0033.

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This chapter provides a broad overview of the state of research in the genetics of the major anxiety disorders (ADs). They exhibit moderate familial aggregation and heritability due to genetic risk factors that are shared between them as well as those that are disorder-specific. Many candidate gene association studies have been published, with a small set of genes that have been consisted validated for their role in one or more anxiety phenotypes. Genome-wide association studies of ADs are in their infancy, with a handful of published studies for each disorder so far and more to come conducted
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Samuels, Jack, Marco A. Grados, Elizabeth Planalp, and O. Joseph Bienvenu. Genetic Understanding of OCD and Spectrum Disorders. Edited by Gail Steketee. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780195376210.013.0025.

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This chapter reviews the evidence for the genetic etiology of OCD and spectrum conditions. A genetic basis is supported by the familial aggregation of OCD; evidence for involvement of genes of major effect in segregation analyses; and higher concordance for OCD in identical than non-identical twins. Recent studies also support linkage of OCD to specific chromosomal regions and association of OCD with specific genetic polymorphisms. However, specific genes causing OCD have not yet been firmly established. The search for genes is complicated by the clinical and etiologic heterogeneity of OCD, as
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Ugarte-Gil, Manuel F., and Graciela S. Alarcón. History of systemic lupus erythematosus. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198739180.003.0001.

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The first description of cutaneous ulcerations consistent with systemic lupus erythematosus (SLE) has been attributed to Hippocrates. The term lupus first appeared in English literature in the tenth century. Until the nineteenth century, however, this term was used to describe different conditions. Osler first recognized that organ involvement may occur with or without skin involvement. With the discovery of LE cells and autoantibodies, the use of lupus murine models, and the recognition of familial aggregation and the importance of genetic factors, the pathogenesis of SLE started to be unrave
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Feinberg, Melanie. Everyday Adventures with Unruly Data. The MIT Press, 2022. http://dx.doi.org/10.7551/mitpress/14198.001.0001.

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Paired informal and scholarly essays show how everyday events reveal fundamental concepts of data, including its creation, aggregation, management, and use. Whether questioning numbers on a scale, laughing at a misspelling of one's name, or finding ourselves confused in a foreign supermarket, we are engaging with data. The only way to handle data responsibly, says Melanie Feinberg in this incisive work, is to take into account its human character. Though the data she discusses may seem familiar, close scrutiny shows it to be ambiguous, complicated, and uncertain: unruly. Drawing on the tools o
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Randhawa, Gurvaneet S., and Edwin A. Lomotan. Harnessing Big Data-Based Technologies to Improve Cancer Care. Edited by David A. Chambers, Wynne E. Norton, and Cynthia A. Vinson. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190647421.003.0034.

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Big data promises to harness the power of advanced computing to transform health and health care, including cancer research and care delivery. In health care, big data can be generated by administrative and clinical processes, by patients and families, and by machines. Ultimately, the goal of big data is to transform data into actionable knowledge with attention to four dimensions: person-level data collection; data access, exchange, and aggregation; population-level analytics; and provider, researcher, or patient-facing clinical decision support. A fabric of trust forms the basis for policies
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Piper, Ross. Extinct Animals. Greenwood Publishing Group, Inc., 2009. http://dx.doi.org/10.5040/9798400649219.

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Everyone is familiar with the dodo and the wooly mammoth, but how many people have heard of the scimitar cat and the Falkland Island fox? Extinct Animals portrays over 60 remarkable animals that have been lost forever during the relatively recent geological past. Each entry provides a concise discussion of the history of the animal—how and where it lived, and how it became extinct—as well as the scientific discovery and analysis of the creature. In addition, this work examines what led to extinction—from the role of cyclical swings in the Earth's climate to the spread of humans and their activ
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Book chapters on the topic "Familial aggregation"

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Naj, Adam C., Yo Son Park, and Terri H. Beaty. "Detecting Familial Aggregation." In Methods in Molecular Biology. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-555-8_8.

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Naj, Adam C., and Terri H. Beaty. "Detecting Familial Aggregation." In Methods in Molecular Biology. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7274-6_8.

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Wang, Xiaoling, and Harold Snieder. "Familial Aggregation of Blood Pressure." In Pediatric Hypertension. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60327-824-9_14.

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Snieder, Harold. "Familial Aggregation of Blood Pressure." In Pediatric Hypertension. Humana Press, 2004. http://dx.doi.org/10.1007/978-1-59259-797-0_15.

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Wang, Xiaoling, and Harold Snieder. "Familial Aggregation of Blood Pressure." In Pediatric Hypertension. Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-490-6_14.

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Wang, Xiaoling, and Harold Snieder. "Heritability and Familial Aggregation of Blood Pressure." In Pediatric Hypertension. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-31107-4_14.

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Wang, Xiaoling, and Harold Snieder. "Heritability and Familial Aggregation of Blood Pressure." In Pediatric Hypertension. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-31420-4_14-1.

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Nagasaka, Takamura. "Familial Amyloidotic Polyneuropathy and Transthyretin." In Protein Aggregation and Fibrillogenesis in Cerebral and Systemic Amyloid Disease. Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-94-007-5416-4_21.

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Aoki, Kunio, and Hiroshi Ogawa. "Familial Cancer Among Cancer Patients Registered at the Aichi Cancer Registry - Heterogeneity of Aggregation of Familial Cancer." In Familial Cancer Control. Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-77582-6_26.

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Malone, Kathleen E., and Kerryn W. Reding. "Inherited Predisposition: Familial Aggregation and High Risk Genes." In Breast Cancer Epidemiology. Springer New York, 2009. http://dx.doi.org/10.1007/978-1-4419-0685-4_13.

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Conference papers on the topic "Familial aggregation"

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Taytard, Jessica, Laurence Jordan, Pascal Garrec, Camille Aupiais, and Nicole Beydon. "Familial aggregation of obstructive sleep apnea syndrome based on a pediatric index case." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa2344.

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Chandra, D., EJ Campbell, SI Rennard, et al. "Familial Aggregation of Augmentation Therapy Use in Severe Alpha-1-Antitrypsin (AAT) Deficiency." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a3526.

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Schwartz, Ann G. "Abstract IA03: Lung cancer risk in African Americans: Familial aggregation and genetic susceptibility." In Abstracts: Eighth AACR Conference on The Science of Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; November 13-16, 2015; Atlanta, Georgia. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7755.disp15-ia03.

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Fang, Yixin. "An Application of a Theorem of Johnstone and Forrester to Testing for Familial Aggregation." In 2008 International Conference on Biomedical Engineering And Informatics (BMEI). IEEE, 2008. http://dx.doi.org/10.1109/bmei.2008.349.

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Ganapati, A., GU Arunachal, S. Arya, et al. "403 Study of familial aggregation of autoimmune diseases in asian indian lupus patients (PROBANDS)." In LUPUS 2017 & ACA 2017, (12th International Congress on SLE &, 7th Asian Congress on Autoimmunity). Lupus Foundation of America, 2017. http://dx.doi.org/10.1136/lupus-2017-000215.403.

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Alexandru, C., M. Bojinca, S. Bezedica, et al. "AB0655 FAMILIAL AGGREGATION OF AUTOIMMUNE DISEASES IN PATIENTS WITH RHEUMATOID ARTHRITIS- A ROMANIAN STUDY." In EULAR 2024 European Congress of Rheumatology, 12-15 June. Vienna, Austria. BMJ Publishing Group Ltd and European League Against Rheumatism, 2024. http://dx.doi.org/10.1136/annrheumdis-2024-eular.4262.

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Nagayama, R., A. Hattori, I. Fuse, T. Takeshige, S. Takizawa, and A. Shibata. "PLATELET IONIZED CALCIUM MOBILIZATION (AEQUORIN METHOD) IN PATIENTS WITH PRIMARY PLATELET DYSFUNCTION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644571.

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Intracellular calcium level of platelets of the patients with primary platelet dysfunction (thrombasthenia, platelet cyclo-oxygenase deficiency, familial defect of A23187 induced platelet aggregation, Hermansky-Pudlak syndrome. Bernard-Soulier syndrome, each 1 case, and other 3 cases of platelet release mechanism defect of unknown etiology) were measured with the photoprotein Aequorin according to the method by Johnson et al. The peak level and the lag time to the peak were evaluated. Activation was done by 4 or more different concentrations of either thrombin (0.125-1.0μ/ml), A23187 (0.25-2.0
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Samama, M., J. Conard, M. H. Horellou, G. Nguyen, Van Dreden, and J. H. Soria. "ABNORMALITIES OF FIBRINOGEN AND FIBRINOLYSIS IN FAMILIAL THROMBOSIS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643716.

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We have reviewed our own experience (400 patients with documented thromboembolic disease) as well as that recorded in the literature. Impaired fibrinolysis after venous occlusion (VO) was the most common finding in patients with history of thrombosis (35% in our series). In contrast, very few families with such an alteration and thrombosis have been reported, suggesting that this disorder is most frequently acquired. In a series of 59 patients with history of thromboembolism, 25 patients with an abnormal responseto an 10 min. V0 on 2 different occasions (group A) were compared with 34 patients
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Pal, Partha, and Rupa Banerjee. "IDDF2018-ABS-0268 Familial aggregation of inflammatory bowel disease in india: prevalence, risks and impact on disease behaviour." In International Digestive Disease Forum (IDDF) 2018, Hong Kong, 9–10 June 2018. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2018. http://dx.doi.org/10.1136/gutjnl-2018-iddfabstracts.186.

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Smew, Awad, Cecilia Lundholm, Lars Sävendahl, Paul Lichtenstein, and Catarina Almqvist. "Familial co-aggregation of asthma and type 1 diabetes mellitus in children– a Swedish population-based cohort study." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.1214.

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