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1

Medeiros, Célia Maria Santos Vieira de. ""O produtor familiar rural e a dinâmica econômica e social do espaço rural da região de Presidente Prudente nos anos 1980-90"." Universidade de São Paulo, 2003. http://www.teses.usp.br/teses/disponiveis/8/8136/tde-19032004-172610/.

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Essa pesquisa objetiva compreender a dinâmica espacial do Sudoeste Paulista, através de abordagem econômica e social do espaço rural, analisando e refletindo sobre o universo da produção agrícola familiar e as possibilidades futuras deste setor frente às políticas públicas, as possíveis mudanças no dinamismo regional, e os limites que os mesmos têm enfrentado com relação à estrutura fundiária, à produção, à comercialização, aos recursos financeiros, ao acesso à tecnologia, à assistência técnica, sua representação e atuação em associações, cooperativas, sindicatos e outras entidades. As áreas pesquisadas fazem parte do Escritório de Desenvolvimento Rural de Presidente Prudente, composto de 21 municípios, entre os estratos de área de até 100 hectares. No levantamento de campo foram entrevistados produtores rurais, destacando-se questões ligadas à unidade de produção, bem como à unidade social dos agricultores familiares. A região estudada, embora apresente, desde sua formação histórica, alta concentração fundiária de caráter capitalista, com predomínio da atividade pecuária de corte extensiva, não levou, necessariamente, ao desaparecimento das unidades de produção familiares, fossem elas pequenas ou médias. Tampouco levou a uma homogeneização da produção; antes, observa-se uma dinâmica que muitas vezes inclui múltiplos caminhos, os quais proporcionam uma adaptação contraditória frente às novas circunstâncias sociais e de produção. Com relação às políticas públicas para o setor destacado neste estudo, verifica-se que o Programa Nacional de Fortalecimento da Agricultura Familiar não foi, até agora, suficiente para atender, de forma eficaz, os produtores familiares. A comercialização indireta da produção e a insegurança com relação aos preços foram fatores destacados, entre outros aspectos, como limitantes para o produtor familiar, que mostrou resistência em adotar formas de organização social que pudessem protegê-lo. Entretanto, através de estratégias, esses produtores têm sido os responsáveis por parte significativa da produção agropecuária regional, bem como da absorção de mão-de-obra no campo. Neste sentido, analisando-se processos sociais concretos, apreendem-se a diversidade e a complexidade de possibilidades neles contidas, podendo, então, apontar caminhos que possam trazer transformações ao dinamismo regional.<br>This study aims to understand the space dynamics of the Paulista Southwestern region, through the economic and social approach of the rural, analyzing and reflecting on the overall family agricultural production and its future possibilities before public policies, the possible shifts in the regional dynamics, and the limits that they have faced in relation to land structure production, trade, financial resources, access to technology, and technical assistance, its representation and performance in associations, cooperatives, unions and other entities. The areas researched are parts of the Presidente Prudente Rural Development Office, formed by 21 counties, in up-to-100-hectare area levels. During the field survey, rural producers were interviewed, emphasizing matters connected to the production unit, as well as to the social unit of the family farmers. The region considered, although it has presented a high-level land concentration of capitalist character since its historical formation, and in which the animal husbandry activity of extensive slaughter has been predominant, has necessarily led neither to the disappearance of the little or large family production units, nor to a production homogenity; instead, I have observed a dynamics that has often included multiple ways, which have provided a contradictory adaptation before the new social and production circumstances. In relation to public policies for the field focused in this study, I have verified that the Family Agriculture Development National Program has not been enough to assist the family producers efficiently up to now. The indirect commercialization of the production and the insecurity in relation to prices were the main aspects in focus, among others, as limits for the family producer, who has showed resistance in adapting ways of social organization which could protect them. Nevertheless, through strategies, these very producers have been responsible for a meaningful part of the regional agricultural and animal husbandry production, as well as for labour absorption in the country. Therefore, in analyzing concrete social processes, I have realized the diversity and complexity of possibilities within them, so that, I believe it is able to indicate ways that could bring changes to the regional dynamics.
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2

Orfi, Nihal Mohamed Sherif. "Harnessing Product Complexity: An Integrative Approach." Diss., Virginia Tech, 2011. http://hdl.handle.net/10919/77292.

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In today's market, companies are faced with pressure to increase variety in product offerings. While increasing variety can help increase market share and sales growth, the costs of doing so can be significant. Ultimately, variety causes complexity in products and processes to soar, which negatively impacts product development, quality, production scheduling, efficiency and more. Product variety is just one common cause of product complexity, a topic that several researchers have tackled with several sources of product complexity now identified. However, even with such progress, product complexity continues to be a theoretical concept, making it difficult for companies to fully implement advances and fully manage product complexity. More and more companies are relying on product family design to handle product variety. Broadly, a product family can be defined as a group of products sharing common elements. The advantages for companies using product family strategies can be significant: they enable efficient derivation of product variants, reduce inventory and handling costs, as well as setup and retooling time. The design challenge however, is to select the product platform to generate a variety of products with minimum deviation from individual requirements. Accordingly, the structure of product families makes designing and evaluating them a challenging process. In order to fully embrace the relationships between variety, product complexity, and product families an understanding of product complexity causes and impacts is essential. This research begins by introducing four main dimensions of product complexity within the context of a generalized definition. Product complexity indicators suitable in product design, development and production are derived. By establishing measurements for the identified indicators and using clustering techniques, a complexity evaluation approach for product family designs is also developed in this research. The evaluation approach is also applied on a component basis, to identify Critical Components that are main sources and contributors of complexity within product families. By standardizing identified Critical Components, product complexity levels and associated costs can be managed. A case application of three product families from a tire manufacturing company is used to verify that this research approach is suitable for evaluating and managing product complexity in product families.<br>Ph. D.
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3

Petersson, Rickard. "Managing product family variance : Development of product family architecture and its realization in a PLM system." Thesis, Tekniska Högskolan, Högskolan i Jönköping, JTH, Industriell produktutveckling, produktion och design, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-44698.

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Singh, Rahul. "Models for integrated product family development /." Digital version accessible at:, 1998. http://wwwlib.umi.com/cr/utexas/main.

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Gupta, Saurabh. "Design methodologies for family-based development of products /." Digital version accessible at:, 1998. http://wwwlib.umi.com/cr/utexas/main.

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6

Yearsley, Jonathan D. "Product family design using Smart Pareto filters /." Diss., CLICK HERE for online access, 2009. http://contentdm.lib.byu.edu/ETD/image/etd2687.pdf.

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Yearsley, Jonathan D. "Product Family Design Using Smart Pareto Filters." BYU ScholarsArchive, 2008. https://scholarsarchive.byu.edu/etd/1664.

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Product families are frequently used to provide consumers with a variety of appealing products and to help maintain reasonably low production costs for manufacturers. Three common objectives in the design of product families are used to balance the interests of both consumers and manufacturers. These objectives are to maximize (i) product performance, (ii) product distinctiveness as perceived by the consumer, and (iii) product commonality as seen by the manufacturer. In this thesis, three methods are introduced that use multiobjective optimization and Smart Pareto filtering to satisfy the three objectives of product family design. The methods are progressive in nature and begin with the selection of product family members using Smart filtering and develop through the establishment of scale- based product platforms to the design of combined scale- based and module-based product platforms. Each of the methods is demonstrated using a well-know universal electric motor example problem. The results of each method are then compared to a benchmark electric motor product family that was previously defined in the literature. Additionally, a pressure vessel example problem is used to further demonstrate the first of the three methods.
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Arnold, Harry C. "Product Placement during the Family-Viewing Hour." Digital Commons @ East Tennessee State University, 2006. https://dc.etsu.edu/etd/2238.

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The so-called family-viewing hour, the eight to nine o’clock hour of prime time, is one of the most watched hours of television by both adults and children. Advertisers, of course, favor shows that draw large audiences so their product presentations or commercials are witnessed by masses of people. Now, because of videocassette recorders and other similar control devices, viewers are eliminating commercials from their viewing experience1 and advertisers are clamoring for new ways to get their products into the mind of the consumer.2 To counteract this commercial avoidance by consumers, advertisers are embedding products within television programming thereby hindering the viewer’s ability to eliminate commercials or product promotions. The result is that products that are normally not viewed become part of the viewing experience. This study revealed that the family-viewing hour is laden with product placements that include a variety of different types of products and brands.
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Gonzalez-Zugasti, Javier P. (Javier Patricio) 1965. "Models for platform-based product family design." Thesis, Massachusetts Institute of Technology, 2000. http://hdl.handle.net/1721.1/9300.

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Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2000.<br>Includes bibliographical references (p. 95-97).<br>Platform-based product families have been an effective way for companies to offer increased variety into markets, while containing the resulting complexity of developing large numbers of products. A product platform is the set of resources - components, processes, technologies, and knowledge - that are shared across multiple products offered by a firm. The products derived from that common platform are called the variants, and the set of variants forms a product family. This thesis presents a theoretical basis for modeling the design of platform-based product families, as well as practical implementations based on those models. The problem is formulated as an optimization, where the requirements of the desired variants must be balanced against family objectives, such as maximizing the value of developing the family. A general case is formulated that covers the effects of using a platform-based design on the benefits and investments required to produce the desired family. The problem is then simplified into a two-step optimization approach to apply it to actual design situations for complex products. The first stage considers the technical details of creating feasible product families that satisfy the variants' requirements while optimizing the expected value to the firm. The second stage evaluates the design alternatives generated by the first step, considering the effects of uncertainty during the actual development of the family on its value to the firm. This evaluation is then used to select the most appropriate choice of family design. A case study of the design of multiple NASA exploratory space missions based on alternative telecommunications technology platforms is shown. Applying the approach resulted in several alternative family designs, some of which had not been previously considered viable. The resulting candidate designs were evaluated through the use of decision analysis models developed in this thesis, which calculate the value to the firm of each design. Simulation was then used to evaluate the value of each alternative and its flexibility to changes in uncertain factors during the development process. As a reference, a Pugh-type selection method (a qualitative, multi-criteria approach) was also explored and applied to the example of platform-based spacecraft design.<br>by Javier P. Gonzalez-Zugasti.<br>Ph.D.
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Li, Yanfeng. "Multi-platform strategy and product family design." Diss., Virginia Tech, 2010. http://hdl.handle.net/10919/26353.

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The application of product families and platforms has gained attention as a promising approach to achieving organizational objectives that provide customers with mass customized products while allowing for significant savings from commonality and reuse strategies. While the single-platform strategy has been widely studied, it may lead to the over expansion of the product family. Designers have to either continuously extend the exiting platform and/or impose strict constraints on new variants in order that there is a fit. On the one hand, continuously “extending“ or “'stretching“ the platform forces the platform to become overburdened and less efficient. On the other hand, imposing strict constraints on new variants will force new variants to compromise performances. In this research, the concept of a multi-platform strategy has been put forward to reduce or eliminate negative effects of the single-platform strategy by coordinating products in a complex product family into two or more platforms to provide enough product variety as well as commonality. The method is developed by adopting and synthesizing various tools and concepts from different research areas, such as design management tools, clustering analysis, statistics, decision analysis, mathematical programming, and engineering costing. The product assets that can be shared by the products are determined through product asset value analysis and redesign effort analysis. The number of platforms is flexibly determined by a hierarchical clustering method based on product similarity/dissimilarity. The product-platform assignment problem is simultaneously solved during the clustering process. A multi-objective optimization model is formulated to determine the design specifications and address the product positioning. A Consistent Aggregate Function Formation Method (CAF2M) is put forward to convert the multi-objective optimization model into a single-dimension problem that can quantitatively balance the tradeoff among the multiple objectives. To evaluate the economic benefit from the platform-based product development, an adjusted Activity-Based Costing approach is utilized to identify the cost savings with the consideration of learning effects. A case application with seven automobile models is utilized to illustrate the proposed multi-platform strategy. The method was found helpful for determining and integrating critical design information into the design of product families and platforms.<br>Ph. D.
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Canela, Sánchez Jordi. "On a Family of Degree 4 Blaschke Products." Doctoral thesis, Universitat de Barcelona, 2015. http://hdl.handle.net/10803/292612.

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This PhD thesis belongs to the area of discrete dynamical systems in the complex plane, i.e. the iteration of analytic functions in one complex variable. Given a rational map f from the Riemann sphere onto itself, we consider the dynamical system given by its iterates. The Riemann sphere splits into two totally f-invariant subsets: the Fatou set, which is defined to be the set of points z where the family {f^n} is normal in some neighborhood of z, and its complement, the Julia set. The dynamics of the points in the Fatou set are stable in the sense of normality or equicontinuity whereas the dynamics in the Julia set present chaotic behavior. This thesis focuses on the study of the family of Blaschke products Ba(z)=z^3(z-a)/(1-\bar{a}z), where a and z are complex numbers. We study its parameter and its dynamical planes using intensive use of quasiconformal surgery techinques, which allow us to build rational maps with prescribed dynamics using quasiregular maps as models. The thesis is structured as follows. In Chapter 1 we give an overview on the preliminary results used throughout the thesis. In Chapter 2 we give an introduction to quasiconformal surgery. In Chapter 3 we give an overview of the dynamical plane of the Blaschke products Ba. We begin by studying their basic properties. Afterwards we show that the maps Ba cannot have doubly connected rotation domains (Herman rings) (Proposition 3.2.3) and prove a criterion of connectivity of the Julia set of Ba (Theorem 3.2.1). In Chapter 4 we introduce the family Mb of cubic polynomials with a superattracting fixed point. Then we show how to build polynomials Mb from Blaschke products Ba , obtaining a map Γ from a subset of the parameter plane of the Ba to the parameter plane of the polynomials Mb. We also prove that the map Γ is continuous and restricts to a homeomorphism on every disjoint hyperbolic component. In Chapter 5 we study the parameter plane of the Blaschke products Ba. We first describe the symmetries in the parameter plane. Then we classify the different hyperbolic dynamics which may take place and the sets of parameters for which they may happen. Afterwards we build a polynomial-like map for all non-escaping parameters contained in swapping regions which, under certain conditions, may relate the dynamics of Ba with the one of the antipolynomials pc(z) =\bar{z}^2+c (Theorem 5.3.4). Finally we parametrize all disjoint hyperbolic components whose disjoint cycles are bounded and do not lie on the unit circle (Theorem 5.4.2). In Chapter 6 we study the tongues of the Blaschke products Ba. We first prove some of their topological properties such as their connectivity modulo symmetry, their simple connectivity and the existence of a unique tip for every tongue (Theorem 6.2.1). Then we show how bifurcations take place along curves in a neighborhood of every tongue (Theorem 6.3.2). Finally we study how tongues extend in the annulus of parameters a such that 1<|a|<2. In Chapter 7 we study how the degree 4 Blaschke products Ba generalize to degree m+2 families of rational maps for m>2.<br>Aquesta tesi doctoral pertany a l’àmbit dels sistemes dinàmics discrets al pla complex, és a dir, la iteració de funcions analítiques en una variable complexa. Donada una funció racional f de l'esfera de Riemann en ella mateixa, considerem el sistema dinàmic donat pels seus iterats. L'esfera de Riemann es divideix en dos conjunts completament invariants per f el conjunt de Fatou, definit com el conjunt de punts z on la família {f^n} és normal en algun entorn de z, i el seu complement, el conjunt de Julià. La dinàmica de les òrbites del conjunt de Fatou és estable en el sentit de normalitat o equicontinuitat mentre que la dinàmica al conjunt de Julià presenta un caràcter caòtic. Aquesta tesi se centra en l'estudi de la família de productes de Blaschke Ba(z)=z^3(z-a)/(1-\bar{a}z), on a i z són nombres complexos. Estudiem el seu pla de paràmetres i el seu pla dinàmic fent us intensiu de les eines de cirurgia quasiconforme, que ens permeten construir funcions racionals amb una dinàmica prescrita fent servir funcions quasiregulars com a models. Al capítol 1 fem un repàs dels resultats preliminars usats al llarg del text. Primer expliquem els conceptes bàsics de la dinàmica de les funcions racionals. Després fem un repàs de les aplicacions del cercle, tot introduint els conceptes de producte de Blaschke i llengües. Finalment, presentem la fórmula de Riemann-Hurwitz i com s’aplica a la dinàmica de funcions racionals. Al capítol 2 donem una introducció a la cirurgia quasiconforme. Primer de tot definim els conceptes d’aplicació quasiconforme, estructures quasiconformes i “pullback” sota funcions que preserven l’orientació i introduïm el Teorema Mesurable de Riemann. Tot seguit mostrem com els conceptes previs són generalitzats per a funcions que giren l’orientació i veiem com això s’aplica a aplicacions que són simètriques respecte del cercle unitat. Finalment introduïm els conceptes d’aplicació polynomial-like i antipolynomial-like. Al capítol 3 donem una visió general del pla dinàmic dels productes de Blaschke Ba. Comencem estudiant les seves propietats bàsiques. Tot seguit mostrem que les funcions Ba. no poden tenir dominis de rotació doblement connexos (anells de Herman) (Proposició 3.2.3) i provem un criteri de connectivitat del conjunt de Julià dels Ba (Teorema 3.2.1). Al capítol 4 introduïm la família Mb de polinomis cúbics amb un punt fix superatractor. A continuació veiem com construir polinomis Mb a partir de productes de Blaschke Ba, tot obtenint una aplicació Γ que envia un subconjunt de l’espai de paràmetres de Ba a l’espai de paràmetres dels polinomis Mb. També provem que l’aplicació Γ és continua i és un homeomorfisme restringida a cada component hiperbòlica disjunta. Al capítol 5 estudiem l’espai de paràmetres dels productes de Blaschke Ba. Primer de tot en descrivim les simetries. A continuació classifiquem els diferents tipus de comportaments hiperbòlics que es poden donar i veiem a quines regions de l’espai de paràmetres poden aparèixer. Tot seguit construïm una aplicació polynomial-like al voltant de tot paràmetre de no escapament contingut en una regió d’intercanvi que, sota certes condicions, pot relacionar la dinàmica de Ba amb la dels antipolinomis pc(z)=\bar{z}^2+c (Teorema 5.3.4). Finalment parametritzem tota component hiperbòlica disjunta els cicles atractors de la qual són acotats i no rauen al cercle unitat (Teorema 5.4.2). Al capítol 6 estudiem les llengües dels productes de Blaschke Ba. Inicialment provem algunes de les seves propietats topològiques bàsiques com ara la seva connectivitat mòdul simetria, la seva connectivitat simple i l’existència d’una única punta per a cada llengua (Teorema 6.2.1). Tot seguit mostrem com es produeixen les bifurcacions en un entorn de la punta de cada llengua (Teorema 6.3.2). Finalment estudiem com les llengües s’estenen per a paràmetres a tals que 1<|a|< 2. Al capítol 7 estudiem com els productes de Blaschke Ba generalitzen a funcions racionals de grau m+2 per m>2.
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Sahin, Asli. "A Data Clustering Approach to Support Modular Product Family Design." Diss., Virginia Tech, 2007. http://hdl.handle.net/10919/29481.

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Product Platform Planning is an emerging philosophy that calls for the planned development of families of related products. It is markedly different from the traditional product development process and relatively new in engineering design. Product families and platforms can offer a multitude of benefits when applied successfully such as economies of scale from producing larger volumes of the same modules, lower design costs from not having to redesign similar subsystems, and many other advantages arising from the sharing of modules. While advances in this are promising, there still remain significant challenges in designing product families and platforms. This is particularly true for defining the platform components, platform architecture, and significantly different platform and product variants in a systematic manner. Lack of precise definition for platform design assets in terms of relevant customer requirements, distinct differentiations, engineering functions, components, component interfaces, and relations among all, causes a major obstacle for companies to take full advantage of the potential benefits of product platform strategy. The main purpose of this research is to address the above mentioned challenges during the design and development of modular platform-based product families. It focuses on providing answers to a fundamental question, namely, how can a decision support approach from product module definition to the determination of platform alternatives and product variants be integrated into product family design? The method presented in this work emphasizes the incorporation of critical design requirements and specifications for the design of distinctive product modules to create platform concepts and product variants using a data clustering approach. A case application developed in collaboration with a tire manufacturer is used to verify that this research approach is suitable for reducing the complexity of design results by determining design commonalities across multiple design characteristics. The method was found helpful for determining and integrating critical design information (i.e., component dimensions, material properties, modularization driving factors, and functional relations) systematically into the design of product families and platforms. It supported decision-makers in defining distinctive product modules within the families and in determining multiple platform concepts and derivative product variants.<br>Ph. D.
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Simpson, Timothy W. "A concept exploration method for product family design." Diss., Georgia Institute of Technology, 1998. http://hdl.handle.net/1853/17508.

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Freeman, Dane Fletcher. "A product family design methodology employing pattern recognition." Diss., Georgia Institute of Technology, 2013. http://hdl.handle.net/1853/50267.

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Sharing components in a product family requires a trade-off between the individual products' performances and overall family costs. It is critical for a successful family to identify which components are similar, so that sharing does not compromise the individual products' performances. This research formulates two commonality identification approaches for use in product family design and investigates their applicability in a generic product family design methodology. Having a commonality identification approach reduces the combinatorial sharing problem and allows for more quality family alternatives to be considered. The first is based on the pattern recognition technique of fuzzy c-means clustering in component subspaces. If components from different products are similar enough to be grouped into the same cluster, then those components could possibly become the same platform. Fuzzy equivalence relations that show the binary relationship from one products' component to a different products' component can be extracted from the cluster membership functions. The second approach builds a Bayesian network representing the joint distribution of a design space exploration. Using this model, a series of inferences can be made based on product performance and component constraints. Finally the posterior design variable distributions can be processed using a similarity metric like the earth mover distance to identify which products' components are similar to another's.
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Thompson, K. N., Ivy A. Click, R. A. Best, S. K. Thacker, and Russell W. Brown. "Acute Eticlopride Treatment Alleviates Cognitive Deficits Produced by Neonatal Quinpirole Treatment." Digital Commons @ East Tennessee State University, 2004. https://dc.etsu.edu/etsu-works/6408.

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This study was designed to investigate the effects of acute eticlopride (0.02 mg/kg, D2 antagonist) treatment, given immediately before training, in rats neonatally treated with quinpirole, which has been shown to produce long-term D2 receptor supersensitization. Rats were given quinpirole (1mg/kg) or saline treatment from P1-21. Beginning on P22, rats were administered eticlopride or saline (i.p.) fifteen mins before each of seven days of training. Rats were tested on the Morris water task (MWT). For the first three consecutive days, rats were tested on the place version of the MWT with a stationary platform. Animals were given 24 training trials followed by a probe trial, and swim patterns were analyzed with platform removed. The next day, animals began testing on the match-to-place version for four consecutive days and two daily trials were given with the platform moved to a new location each day. On both the search time and target visit measures of the probe trial, animals neonatally treated with quinpirole demonstrated a deficit, and eticlopride eliminated this deficit. Interestingly, animals neonatally treated with saline but given eticlopride before training also demonstrated a deficit on both measures. On the match-to-place version, the difference in latency to locate the platform between the two daily trials served as the dependent measure. Similar to the MWT place version, eticlopride treatment eliminated deficits produced by neonatal quinpirole treatment on this task, and eticlopride produced a deficit in saline controls. This study demonstrates that in a model of dopamine D2 supersensitivity, it appears that the increased sensitivity of the D2 receptor is important for cognitive function.
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Siu, Power Po Wa. "Development of a building configurator : product family architecture approach /." View abstract or full-text, 2005. http://library.ust.hk/cgi/db/thesis.pl?IEEM%202005%20SIU.

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Zamirowski, Erik J. (Erik John) 1973. "Product family architecture modularity using function and variety heuristics." Thesis, Massachusetts Institute of Technology, 1999. http://hdl.handle.net/1721.1/9058.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1999.<br>Includes bibliographical references (leaves 83-84).<br>This thesis examines the market and functional aspects of developing a product portfolio architecture. Product use based market analysis of customer needs and product features is performed to determine the set of portfolio target values. The variation in these target values among and within customers is interpreted to yield a portfolio architecture recommendation for each feature. Correlation analysis is used to reduce the combinatorial complexity of target values according to market trends. Functional representation of a product portfolio is achieved through a monolithic function structure created by combining individual product use function structures. This function structure is partitioned into function clusters, representing potential module options, using a set of function modularity and variety modularity heuristics. The function modularity heuristics reveal relationships among the product functions according to the interconnection and causality of the functions. The variety heuristic, through which product features are mapped to the functions that deliver them, reveals the potential for variety-dependent modularity. The set of function clusters is compared to determine the degree of interaction among them. When variety function clusters are not orthogonal to each other, the portfolio architecture rules must be modified to compensate for this coupling, or portfolio variety will be compromised. An algorithm is used to reconcile interactions among the function clusters to maximize portfolio variety. The result is a set of function clusters for candidate product modules that achieves the best product variety given functional constraints. The process is exemplified using a portfolio of xerographic products.<br>by Erik J. Zamirowski.<br>S.M.
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Estrada, David C. (David Charles) 1976. "Product family formation in linked-cell manufacturing system design." Thesis, Massachusetts Institute of Technology, 2000. http://hdl.handle.net/1721.1/89268.

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Martins, Lanna André Luiz Peron. "Feature-family-based reliability analysis of software product lines." reponame:Repositório Institucional da UnB, 2017. http://repositorio.unb.br/handle/10482/31239.

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Tese (doutorado)—Universidade de Brasília, Instituto de Ciências Exatas, Departamento de Ciência da Computação, 2017.<br>Submitted by Raquel Almeida (raquel.df13@gmail.com) on 2017-12-22T10:53:47Z No. of bitstreams: 1 2017_AndréLuizPeronMartinsLanna.pdf: 4218714 bytes, checksum: a2374ea747f76f8e47ee2377c3a3a989 (MD5)<br>Approved for entry into archive by Raquel Viana (raquelviana@bce.unb.br) on 2018-02-15T20:00:30Z (GMT) No. of bitstreams: 1 2017_AndréLuizPeronMartinsLanna.pdf: 4218714 bytes, checksum: a2374ea747f76f8e47ee2377c3a3a989 (MD5)<br>Made available in DSpace on 2018-02-15T20:00:30Z (GMT). No. of bitstreams: 1 2017_AndréLuizPeronMartinsLanna.pdf: 4218714 bytes, checksum: a2374ea747f76f8e47ee2377c3a3a989 (MD5) Previous issue date: 2018-02-15<br>Contexto: Técnicas de verificação têm sido aplicadas para garantir que sistemas de software atinjam níveis de qualidade desejados e atenda a requisitos funcionais e nãofuncionais. Entretanto a aplicação dessas técnicas de verificação em linhas de produto de software é desafiador devido à explosão combinatorial do número de produtos que uma linha de produtos pode instanciar. As técnicas atuais de verificação de linhas de produtos utilizam model checking simbólico e informações sobre variabilidade para otimizar a análise, mas ainda apresentam limitações que as tornam onerosas ou inviáveis. Em particular, as técnicas de verificação do estado da arte para análise de confiabilidade em linhas de produto são enumerativas o que dificulta a aplicabilidade das mesmas devido à explosão combinatorial do espaço de configurações. Objetivo: Os objetivos dessa tese são os seguintes: (a) apresentar um método eficiente para calcular a confiabilidade de todas as configurações de uma linha de produtos de sotware composicional ou anotacional à partir de seus modelos comportamentais UML, (b) fornecer uma ferramenta que implemente o método proposto e, (c) relatar um estudo empírico comparando o desempenho de diferentes estratégias de análises de confiabilidade para linhas de produto de software. Método: Esse trabalho apresenta uma nova estratégia de análise feature-family-based para calcular a confiabilidade de todos os produtos de uma linha de produtos de software (composicional ou anotacional). O passo feature-based da estratégia divide os modelos comportamentais em unidades menores para que essas possam ser analisadas mais eficientemente. O passo family-based realiza o cálculo de confiabilidade para todas as configurações de uma só vez ao avaliar as expressões de confiabilidade em termos de uma estrutura de dados variacional adequada. Resultados: Os resulstados empíricos mostram que a estratégia feature-family-based para análise de confiabilidade supera, em termos de tempo e espaço, quatro outras estratéfias de análise do estado da arte (product-based, family-based, feature-product-based e family-product-based) para a mesma propriedade. No contexto da avaliação e em comparação com as outras estratégias, a estratégia feature-family-based foi a única capaz de escalar a um crescimento do espaço de configuração da ordem de 220. Conclusões: A estratégia feature-family-based utiliza e se beneficia das estratégias feature- e family- ao domar o crescimento dos tamanhos dos modelos a serem analizados e por evitar a enumeração de produtos inerentes a alguns métodos de análise do estado da arte.<br>Context: Verification techniques are being applied to ensure that software systems achieve desired quality levels and fulfill functional and non-functional requirements. However, applying these techniques to software product lines is challenging, given the exponential blowup of the number of products. Current product-line verification techniques leverage symbolic model checking and variability information to optimize the analysis, but still face limitations that make them costly or infeasible. In particular, state-of-the-art verification techniques for product-line reliability analysis are enumerative which hinders their applicability, given the latent exponential blowup of the configuration space. Objective: The objectives of this thesis are the following: (a) we present a method to eciently compute the reliability of all configurations of a compositional or annotationbased software product line from its UML behavioral models, (b) we provide a tool that implements the proposed method, and (c) we report on an empirical study comparing the performance of dierent reliability analysis strategies for software product lines. Method: We present a novel feature-family-based analysis strategy to compute the reliability of all products of a (compositional or annotation-based) software product line. The feature-based step of our strategy divides the behavioral models into smaller units that can be analyzed more eciently. The family-based step performs the reliability computation for all configurations at once by evaluating reliability expressions in terms of a suitable variational data structure. Results: Our empirical results show that our feature-family-based strategy for reliability analysis outperforms, in terms of time and space, four state-of-the-art strategies (product-based, family-based, feature-product-based, and family-product-based) for the same property. In the evaluation’s context and in comparison with the other evaluation strategies, it is the only one that could be scaled to a 220-fold increase in the size of the configuration space. Conclusion: Our feature-family-based strategy leverages both feature- and familybased strategies by taming the size of the models to be analyzed and by avoiding the products enumeration inherent to some state-of-the-art analysis methods.
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HONORATO, KATHARINE DE ANGELI. "PRODUCTION OPTIMIZATION: A CASE STUDY OF A FAMILY BUSINESS THAT PRODUCES SNACKS." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2013. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=29186@1.

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PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO<br>COORDENAÇÃO DE APERFEIÇOAMENTO DO PESSOAL DE ENSINO SUPERIOR<br>CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO<br>PROGRAMA DE SUPORTE À PÓS-GRADUAÇÃO DE INSTS. DE ENSINO<br>O cenário atual do mercado brasileiro é composto principalmente por micro e pequenas empresas, que crescem a cada ano, mas possuem baixa taxa de sobrevivência se comparada a de outros países. Uma vez que esses empreendimentos contribuem fortemente com o PIB do país, garantir a sobrevivência desse grupo é de suma importância para a economia brasileira. Neste trabalho, foi desenvolvido um modelo matemático para otimizar a produção de uma microempresa produtora de salgados. Através do modelo, determinam-se as quantidades de insumos a serem compradas de fornecedores, as quantidades a serem produzidas de itens intermediários e finais, em cada período do horizonte de planejamento, de modo a atender a demanda a um menor custo total. Para isso, foi realizado um levantamento sobre as características da produção da microempresa estudada e observou-se que um dos motivos que a impedem de ser competitiva é a falta de conhecimento e de aplicação de ferramentas de planejamento e controle da produção. Para avaliar o desempenho do modelo desenvolvido foram realizados testes com dados reais, e, os resultados obtidos para diferentes cenários da demanda mostram que o modelo pode ser útil para apoiar as decisões de dimensionamento de lotes de compra e de produção, pois mostram que os custos ótimos obtidos são menores que os custos obtidos pela empresa sem o uso da otimização.<br>The current scenario of the Brazilian market is composed mainly of micro and small enterprises that grow every year, but have low survival rate compared to other countries. Once these businesses contribute greatly to the country s GDP, ensuring the survival of this group is of paramount importance to the Brazilian economy. In this work, a mathematical model was developed to optimize the production of a micro producer of snacks. Through the model, the quantities of inputs to be purchased from suppliers and the quantities of intermediate and final items to be produced in each period of the planning horizon are determined, in order to meet demand at a lower total costs. For this, a survey was conducted on the characteristics of the production of the studied micro company and it was observed that one of the reasons that prevent them from being competitive is the lack of knowledge and application of tools for planning and control of production. To evaluate the performance of the developed model tests were carried out with real data, and the results of different scenarios for the demand show that the model can be useful to support decisions on lot sizing of purchasing and production, showing that the obtained optimal costs are less than the costs obtained by the company without the use of optimization.
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21

Kasprzyk, Milena, and milena kasprzyk@freehills com. "Synthetic Studies Towards the Tridachione Family of Marine Natural Products." Flinders University. Chemistry, Physics and Earth Sciences, 2008. http://catalogue.flinders.edu.au./local/adt/public/adt-SFU20081107.085933.

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Since the middle of the 20th century, significant interest has evolved from the scientific community towards the polypropionate family of marine natural products. A number of these compounds have been shown to possess significant biological activity, and this property, as well as their structural complexity, has driven numerous efforts towards their synthesis. The first chapter provides an introduction into the world of polypropionates, with a discussion on synthetic studies into a number of members of the tridachiapyrone family. Fundamental synthetic concepts utilised in this thesis towards the preparation of polyketides are also described, with a focus on their application towards the synthesis of 9,10-deoxytridachione, anti tridachiahydropyrone and syn tridachiahydropyrone. Chapter 2 describes the work undertaken towards the total synthesis of 9,10-deoxytridachione. The novel tandem conjugate addition-Dieckmann condensation of complex enones developed previously in the Perkins group was used to generate anti methylated cyclohexenones as key synthetic intermediates. The conversion of the cyclohexenones into the corresponding cyclohexadienes via allylic alcohols was attempted, utilising a Grignard-mediated reaction to achieve the selective 1,2-reduction. Studies into the Grignard-mediated reduction were also undertaken on seven additional cyclohexenones, in order to investigate the utility and scope of the reaction. The extension of the methodology previously developed for the synthesis of cyclohexenones is the subject of Chapter 3. This section describes investigations into the synthesis of stereochemically-diverse cyclohexenones from complex enones. The conjugate addition-Dieckmann condensation strategy was extended successfully towards the synthesis of a syn methylated cyclohexenone, which allowed the synthesis of the proposed true structure of tridachiahydropyrone to be pursued. The methodology developed in Chapter 3 was utilised in Chapter 4 to synthesise a model system of syn tridachiahydropyrone. A comparative analysis of the NMR data of the syn model, an anti model and anti tridachiahydropyrone with the natural product indicated that the true structure of tridachiahydropyrone may indeed have syn stereochemistry. The synthesis of syn tridachiahydropyrone was attempted, and to this end a suitable cyclohexanone was successfully synthesised. However, the subsequent methylation-elimination cascade failed to furnish the desired syn methylated cyclohexenone, producing only an anti methylated cyclohexanone. The stereochemistry of the methylation was deduced using high and low variable temperature NMR coupled with selective irradiation NOESY.
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22

Sigerson, Ralph Clark. "Formal synthesis of the asbestinin family of marine natural products." Thesis, University of Glasgow, 2012. http://theses.gla.ac.uk/3835/.

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The asbestinins are a sub-class of the ether bridged 2,11-cyclised cembranoid family of marine natural products that have been isolated from octocoral species Briareum Asbestinum. They exhibit high structural complexity and a diverse range of bioactivities that include cytotoxicity against tumour cell lines, potent anti-bacterial properties and antagonism of both histamine and acetylcholine. This report presents the continued efforts in developing an efficient synthetic route to the asbestinins which will be general enough to enable the synthesis of virtually every member of this family of compounds. The key synthetic steps include; a samarium diiodide reductive cyclisation to generate 2,6-syn-5,6-anti tetrahydropyranol motif, oxonium ylide formation with subsequent [2,3]-sigmatropic rearrangement of a functionalised diazoketone and an intramolecular Diels-Alder cycloaddition to construct the cyclohexyl ring. Many studies have been carried out on other sub-classes within the ether bridged 2,11-cyclised cembranoid family of natural products, of particular interest have been the sarcodictyins and cladiellins, the latter of which has been extensively investigated within the Clark group.
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Wilkinson, Roger Lindsay. "Population dynamics and succession strategies of rural industry producers." full-text, 2009. http://eprints.vu.edu.au/1943/1/Roger_Wilkinson_PhD_thesis.pdf.

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Sheep farming in Australia has a long tradition, built up over several generations, of inheritance of the family farm, the occupation of sheep farming and the personal identity around being a sheep farmer. This tradition appears to be under threat, due to a combination of hard times and the long-term and inexorable decline in the terms of trade. I examined this threat to the continuation of family farming in Australia’s sheep industry by describing the demographic structure of the industry, documenting the structural changes and questioning whether the changes actually matter. The work involved demographic analysis of data from recent censuses of population and housing and in-depth interviews with sheep farming families. The average age of Australia’s sheep farmers is increasing, caused mainly by the decrease in entry of young people to the industry. This phenomenon is not confined to Australia’s sheep industry but is widespread and long-term through the industrialised world. Also, as some areas focus on agricultural production and others on amenity consumption, the rural landscape is changing. The changes to the structure of Australia’s sheep industry and the nation’s rural landscapes are driven by substantial forces that cannot be resisted easily. This has implications for policy-makers, extension agents and farm families.
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24

Choubey, Anand M. "Platform based approach for economic production of a product family." Thesis, Manhattan, Kan. : Kansas State University, 2007. http://hdl.handle.net/2097/434.

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25

Schubert, Maxi. "Modular design for a product family ofaesthetic medical laser devices." Thesis, KTH, Maskinkonstruktion (Inst.), 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-226145.

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This thesis covers a product development process carried out at the company “Asclepion Laser Technologies” for a product family of aesthetic medical laser devices. Due to different dimensions and dates of origin, an obvious divergence in the appearance of the present products within the product family had emerged in the company. Since the recognition value of a brand is greatly influenced by its product design the company aspired the development of a uniform design for the whole product family.   For this purpose, the objective of this thesis was the development of a new housing design. A modular design was pursued, to make it applicable for different devices of the same product family. Building multiple devices from the same housing modules reduces the overall production costs by decreasing tooling costs and decreasing the diversity of parts from suppliers. With the use of thermoforming as the predetermined production method, the production costs are kept low in addition.   During the master thesis project, the whole product development process was executed. The present thesis describes the development process in its four different phases, beginning with the pre-studies over ideation, concept development till the development of a final product ready for production. The implementation of suitable methods and tools in this design process, like observational studies and morphological idea generation, is outlined.   In collaboration with a thermoform specialist a CAD-model, ready for production, was delivered. After a revision of the developed product design by a commercial design company the design has been immediately transferred into serial production.<br>Denna uppsats beskriver den produktutvecklingsprocess som genomförts i samarbete med “Asclepion Laser Technologies” i syfte att ta fram ett gemensamt formspråk för en produktfamilj av medicinska lasrar. Eftersom att dessa produkter varierar i storlek såväl som utvecklingsår fanns stora skillnader i deras respektive formspråk. Eftersom att formspråk och design är viktiga för varumärkets identitet så eftersträvade företaget att införa ett gemensamt formspråk för sina produkter.   Examensarbetets syfte var sålunda att ta fram en design för nya kåpor. För att göra designen applicerbar över hela produktfamiljen så eftersträvades ett modulärt system. Genom att nyttja samma kåpor till flera produkter kan dessutom produktionskostnad, verktygskostnad och antal underleverantörer sänkas. Varmforming som preliminär tillverkningsmetod bidrar även det till en låg produktionskostnad.   Arbetet omfattade hela produktutvecklingsprocessen i fyra steg, med förstudie, idégenerering, konceptutveckling och produktionsklart koncept. Användandet av metoder och verktyg för utvecklingsprocessen, såsom observationsstudier morfologisk idégenerering, beskrivs övergripande.   I samarbete med en varmformningsspecialist levererades en produktionsklar CAD-modell. Efter att ha reviderats av ett kommersiellt designföretag har den framtagna designen satts i serieproduktion.
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Liu, C.-K. "A generic assembly relations model for product family variant management." Thesis, Cranfield University, 1999. http://dspace.lib.cranfield.ac.uk/handle/1826/11342.

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The objective of this thesis is to develop generic assembly relations to support variant management to aid the product development for products as families. The advent of the buyers' market has encouraged manufacturers to offer products as families to meet customers needs for differentiation. This creates the corresponding need for representing the product and process variants in a way to support the assessment of impact of product variants. Through the study of literature and standards, the current status of product modelling and product family was captured. Existing models of product model have considered representation of products as one of a kind and do not have the necessary capability to incorporate the variation in production variants that is commonly seen in the assembly of families of product. A Generic Assembly Relations Model (GARM) has been developed to meet the requirements. The generic Bill-of-Material (GBQM) and generic Bill-of-Process (GBQP) have been introduced as a single formalism to represent the product and process variants. The proposed model supports the reuse of product/process variants through the Generic Assembly Relations and GBQM and GBQP. The integration is achieved by the generic relations which act as the bridge between product and process models. This research increases the understanding of how to model product and process in the product family environment. The GARM model works as a production support tool for the product family in the Concurrent Engineering environment. With the GARM model, different views of the requirements can be developed at an early stage; the designer can be supported with feedback information such as the change of product component and assembly process. The GARM model supports variant management to aid the product development for products as families. The impact of the product variant on assembly process can be evaluated through the model. It has been validated by illustrating how the data structure definition supports the evaluation of changes in product family assembly process definition when additional variants are added through an example from the Personal Computer industry.
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Liu, Chi-Kuang. "A generic assembly relations model for product family variant management." Thesis, Cranfield University, 1999. http://dspace.lib.cranfield.ac.uk/handle/1826/11342.

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The objective of this thesis is to develop generic assembly relations to support variant management to aid the product development for products as families. The advent of the buyers' market has encouraged manufacturers to offer products as families to meet customers needs for differentiation. This creates the corresponding need for representing the product and process variants in a way to support the assessment of impact of product variants. Through the study of literature and standards, the current status of product modelling and product family was captured. Existing models of product model have considered representation of products as one of a kind and do not have the necessary capability to incorporate the variation in production variants that is commonly seen in the assembly of families of product. A Generic Assembly Relations Model (GARM) has been developed to meet the requirements. The generic Bill-of-Material (GBQM) and generic Bill-of-Process (GBQP) have been introduced as a single formalism to represent the product and process variants. The proposed model supports the reuse of product/process variants through the Generic Assembly Relations and GBQM and GBQP. The integration is achieved by the generic relations which act as the bridge between product and process models. This research increases the understanding of how to model product and process in the product family environment. The GARM model works as a production support tool for the product family in the Concurrent Engineering environment. With the GARM model, different views of the requirements can be developed at an early stage; the designer can be supported with feedback information such as the change of product component and assembly process. The GARM model supports variant management to aid the product development for products as families. The impact of the product variant on assembly process can be evaluated through the model. It has been validated by illustrating how the data structure definition supports the evaluation of changes in product family assembly process definition when additional variants are added through an example from the Personal Computer industry.
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Poorkiany, Morteza. "Enabling traceability of design rationale using the concept of product family description (PFD)." Thesis, Tekniska Högskolan, Högskolan i Jönköping, JTH, Maskinteknik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-16421.

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This thesis work is based on the previous researches in design automation at Sandvik Coromant. The concept of product family description (PFD) has been introduced to the company to improve documentation of knowledge in engineering design process. Current documentation at the company for engineering design covers mostly the design definition part of the knowledge. PFD is constituted by design definition and completed by design rationale. This kind of documentation improves reusing, revising and expanding the knowledge at the company. On the other side, PFD is an input for design programming and a good engineering design description for a product provides more efficiency in design programming. The project is started by a survey for several principles and applications for knowledge modelling. Product variant master (PVM) and Semantic MediaWiki are selected by the results of the survey. To show the concept of PVM, modelling of a test product is done in product model manager (PMM) software. The main part of the project is setting up product family description (PFD) by capturing design rationale for the test product, implementing in Semantic MediaWiki. Since the design rationale is not documented, it was recorded during several meetings with the designer of the test product. The description is completed by including the argumentations about the rules, figures, dimensions and etc. Also in the project has been tried to improve and revise the description to make it more simple and efficient. Another objective of the project is to show Semantic MediaWiki as a candidate application for modelling knowledge at the company. In this step the applicability and functionality of both PFD and Semantic MediaWiki is seen. In the next stage the project findings and company documentation are evaluated. In this step has been tried to show the pros and cons of the project. The emphasis of the evaluation is on PFD and the alternative application. In the end a conclusion of the whole methods and findings of the project comes with discussion with people who were involved in this work.
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Jacobsen, Jesse M. "TOWARDS THE TOTAL SYNTHESIS OF THE CAPURAMYCIN FAMILY OF NATURAL PRODUCTS." UKnowledge, 2011. http://uknowledge.uky.edu/gradschool_theses/162.

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Despite over a century of advancement, tuberculosis remains a grave threat to world health. In particular, third world countries continue to struggle with the crushing weight of the disease. Furthermore, the emergence of drug resistance in TB strains poses a significant threat to the first world where incidence and mortality is low. The dwindling efficacy of current drug regimens necessitates research into new small molecules capable of arresting the growth and spread of TB. The capuramycin family of nucleoside antibiotics shows strong potential to become part of this new generation of anti-TB small molecules. Indeed, their ability to inhibit Translocase I, a key enzyme in the biosynthesis of bacterial cell walls, makes them exciting targets for medicinal chemistry efforts. The synthesis of the family focused on dividing the molecules into three congruent, synthetically separate parts: the variable amide linked tail, the hexauronic acid linker, and the uridine "head". Construction of the ubiquitous core structure comprised of the hexauronic acid and uridine would allow rapid diversification while the variable tail would allow SAR studies and development of novel new members of the family.
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Romiti, Filippo. "Total synthesis of members of the amphidinolide family of natural products." Thesis, University of Glasgow, 2015. http://theses.gla.ac.uk/6445/.

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The amphidinolides are macrolide natural products isolated from marine dinoflagellates of the genus Amphidinium and most of them display potent cytotoxic activities in vitro. Amphidinolides C-C3, F and T1-5 represent attractive synthetic targets due to a combination of potent bioactivity and complex molecular architecture. This thesis describes the total syntheses of amphidinolides T1, T3 and T4, and the preparation of the C1-C17 fragment of amphidinolides C and F. Concise and high-yielding total syntheses of amphidinolides T1, T3, and T4 have been completed using an alkynyl macrolactone as a common late-stage intermediate. The α-hydroxy ketone motif was installed by sequential alkyne hydrosilylation, epoxidation, and Fleming–Tamao oxidation. A tandem oxonium ylide formation [2,3]-sigmatropic rearrangement reaction was used to construct the trisubstituted tetrahydrofuran core found within the natural products. The C1-C17 fragment of amphidinolides C, C2, C3 and F was synthesised employing [2,3]-sigmatropic rearrangement of an oxonium ylide generated by decomposition of 1-sulfonyl-triazole to construct the trisubstituted tetrahydrofuran ring found in the natural products. The two main segments were conjoined using a Stille cross-coupling reaction that allowed simultaneous installation of the isomerization-prone 1,3-diene unit.
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Powell, Kimberley Jade. "Synthetic and biophysical studies on the tridachiahydropyrone family of natural products." Thesis, University of Nottingham, 2014. http://eprints.nottingham.ac.uk/14228/.

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This thesis primarily details synthetic and biophysical studies on the tridachiahydropyrone family of natural products. The general aim of this work was to explore an hypothesis regarding the location and function of these metabolites, isolated from sacoglossan molluscs. Specifically, it was hypothesised that tridachiahydropyrone is synthesised photochemically from linear polyene precursors via a selective double bond isomerisation-6pi electrocyclisation sequence which occurs within the cell membrane of the producing organism. Furthermore, it was postulated that this reaction sequence, and subsequent photochemical transformations of tridachiahydropyrone into the related products phototridachiahydropyrone and oxytridachiahydropyrone, serve to protect the producing mollusc from the damaging effects of UV radiation. Firstly, the proposed polyene precursors were synthesised using a convergent strategy dependent upon a late-stage Suzuki coupling. Their photochemical, biomimetic conversion into tridachiahydropyrone, phototridachiahydropyrone and oxytridachiahydropyrone, was then accomplished. The interactions of tridachiahydropyrone and its biomimetic precursors with model membrane systems were next explored, using a fluorescence spectroscopic technique. This work demonstrated that the molecules bind to phospholipid vesicles (PLVs) of varying compositions. The synthesis of tridachiahydropyrone within the PLVs was also achieved The propensity of the compounds to act as sunscreens was lastly investigated, by measuring the degree of protection against photochemically-induced lipid peroxidation they conferred on irradiated PLVs, using the thiobarbituric acid reactive substances assay. At high compound concentrations the compounds were found to act as sunscreens, whilst at lower concentrations pro-oxidant activity was observed. In addition to this main work, methodology for the palladium-catalysed cyanation of vinyl halides with acetone cyanohydrin was developed. Conditions were optimised using beta-bromostyrene, and shown to be applicable to a range of diverse substrates. The protocol proved chemoselective for vinyl bromides in the presence of aryl bromides, which were left unaffected and available for further chemical transformations, adding to the synthetic utility of the reaction.
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Ramdharie, Priscilla, and Derk Brinxma. "A family business brand image: Associations affecting consumers’ buying behavior : A study on family business Dafgård, frozen foods." Thesis, Internationella Handelshögskolan, Högskolan i Jönköping, IHH, Marketing and Logistics, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-18130.

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Family business research is a rapidly growing topic of interest. Nevertheless there has been little research explicitly dedicated to the connection between consumers’ and family businesses. This paper gives insight about the influence of the family business brand image and consumers’ purchase intentions. Hereby it was taken into consideration  that  low-involvement and product knowledge can influence this path. This was done by a combination of qualitative and quantitative approaches. The findings showed that consumers associate family business with high quality, passion, heritage, traditions, small companies and craftsmanship. In general these associations do not influence consumers buying behavior. However, specific target groups showed different results. Implications focus on using the family business as a secondary brand image and family businesses should deal with caution when using their origin as a primary brand image.
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Jirapanthong, Waraporn. "A rule-based approach for software traceability on product family systems." Thesis, City University London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.435040.

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Brown, Russell W., J. T. Gass, Ivy A. Click, et al. "Ontogenetic Quinpirole Treatment Produces Spatial Memory Deficits and Reaching Accuracy Enhancement in Rats." Digital Commons @ East Tennessee State University, 2001. https://dc.etsu.edu/etsu-works/6410.

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Past studies have shown that ontogenetic treatment of quinpirole (QNP) produces a number of behavioral effects that can be alleviated by administration of antipsychotics such as haloperidol, providing a useful behavioral screen for disorders such as schizophrenia. In this study, 16 female Sprague-dawley rats were used, with 8 rats injected with QNP(1 mg/kg) and 8 rats injected with saline once daily from postnatal days (PD) 1-11. All rats were behaviorally tested as adults on several tasks: The reference and working memory versions of the Morris water task (MWT), the radial arm maze (RAM), the Whishaw reaching task, and locomotor activity. Results showed that on the MWT, QNP-treated rats demonstrated significant enhancement on acquisition latency of both versions, but a deficit on the probe trial of the reference memory version. The acquisition enhancement was due to hyperlocomotion observed in QNP-treated rats, because these animals demonstrated increased locomotion in an activity chamber compared to controls. On the RAM, QNP-treated rats demonstrated a deficit in reference memory but not working memory, congruent with MWT findings. Interestingly, QNP-treated rats demonstrated a significant enhancement in reaching accuracy on the Whishaw reaching task, which may due to an overactive dopaminergic system. Future studies will analyze underlying mechanisms.
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35

Chan, Fungyee Claudia. "The effects of Chinese immigrant's acculturation and changes in family environment on children's product influence in family purchase decisions." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/MQ39964.pdf.

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36

Beddie, David G. "Isolation, characterisation and synthesis of insecticidal natural products of the Myrtaceae family." Thesis, University of Nottingham, 1998. http://eprints.nottingham.ac.uk/30648/.

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New insecticidal natural products are required to find compounds with higher intrinsic activities to lower field application rates, and with novel modes of action to combat insect pest species which have developed resistance to current commercial insecticides. Using a taxonomic approach, studies on plants of the Myrtaceae family led to the isolation and characterisation of a range of insecticidal natural products 1 - 9 (figure 1). These compounds are all structurally related as they contain a tetramethylcyclohexenedione group, attached to either a terpene or a phloroglucinol moiety. Seven of the nine compounds (1 - 6, 9) are novel. For compounds 7 and 8, no synthesis had been previously reported. The compounds are active against a range of insect species, although in general they are less active than commercial natural products. Further tests show some of the compounds are potent antifeedants. Synthesis of seven of the nine natural products (1 - 5, 7, 8) by short, convergent, stereospecific and high yielding routes was achieved. The synthetic routes were devised to mimic the postulated biosynthesis of the compounds. Reaction of syncarpic acid, an aldehyde and pyrrollidine formed a Mannich base, which on elimination gave a key alkylidene intennediate. This key intermediate was reacted, with either terpenes in Diels-Alder reactions or with phloroglucinols in aromatic alkylation reactions, to synthesise seven of the natural products.
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37

Pakala, Padmavathi Krishna. "Optimal formation of supplier networks for product design and production phases to realize an evolving product family." Diss., Rolla, Mo. : University of Missouri-Rolla, 2007. http://scholarsmine.mst.edu/thesis/pdf/Pakala_completeThesis_09007dcc8043f836.pdf.

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Thesis (M.S.)--University of Missouri--Rolla, 2007.<br>Vita. The entire thesis text is included in file. Title from title screen of thesis/dissertation PDF file (viewed December 5, 2007) Includes bibliographical references (p. 56-62).
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38

Chamberlain, Matthew Kipp. "An Approach to Decision Support for Strategic Redesign." Diss., Georgia Institute of Technology, 2007. http://hdl.handle.net/1853/19838.

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Researchers have paid relatively little attention to the fact that most design activities are actually more like redesign. These activities are characterized by an attempt to leverage experience, knowledge, and the capital that a company has already invested into existing engineering systems. In this dissertation, it is proposed that an approach be developed to aid designers in making decisions in redesign problems when there exist systems to be leveraged and multiple new systems to be created. In addition, strategy is introduced to the problem through the consideration that new systems may not be offered all at once, as is often assumed in product family design research. In this dissertation, the aim of the designer is assumed to be a creation, through redesign, of a series of new systems with desirable and distinct performance levels. In addition, a plan is required to involve as little redesign effort throughout the life of the family of systems as possible The proposed approach is based upon the concepts of Constructal Theory and previous work to create methods for the design of mass customized families of products. The existing methods are abstracted and heavily modified through the infusion of the compromise Decision Support Problems at all stages of the decision-making process. In addition, two indices are developed to represent considerations unique to redesign as opposed to original design. These indices for redesign effort and commonality value are utilized in the overall objective formulation for the approach. Through a thorough validation process and a large number of redesign scenarios, it is shown that the overall approach proposed can lead the designer towards promising redesign plans involving leveraging of existing systems, but that the constructal-inspired approach in and of itself has certain limitations when applied to redesign.
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Wang, Haoyu Roy Utpal. "Graph-based mechanical product family modeling and functional tolerancing for mass customization." Related electronic resource: Current Research at SU : database of SU dissertations, recent titles available full text, 2004. http://wwwlib.umi.com/cr/syr/main.

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40

Goswami, Mohit. "Application of product family design for engineered systems in changing market space." Diss., Rolla, Mo. : Missouri University of Science and Technology, 2008. http://scholarsmine.mst.edu/thesis/pdf/Goswami_09007dcc804feafa.pdf.

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Thesis (M.S.)--Missouri University of Science and Technology, 2008.<br>Vita. The entire thesis text is included in file. Title from title screen of thesis/dissertation PDF file (viewed May 19, 2008) Includes bibliographical references (p. 33-35).
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41

Rosengren, Nils Richard, and Saman Abbasi. "The Impact of Socioemotional Wealth on Product Innovation in a Family Firm." Thesis, Högskolan i Jönköping, Internationella Handelshögskolan, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-44026.

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42

Chang, Min-Wen. "Teamwork for product innovation in Taiwanese family firms : an indigenous psychology perspective." Thesis, Aston University, 2012. http://publications.aston.ac.uk/18790/.

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As the existing team literature mostly excludes context and culture, little is known about how these elements affect real-life team working (Engestrom, 2008; Salas & Wildman, 2009), and how teams work in non-Western settings, such as in Chinese firms (Phan, Zhou, & Abrahamson, 2010).This research addresses this issue by investigating how new product design (NPD) teams use team working to carry out product innovation in the context of Chinese family businesses (CFBs) via an indigenous psychology perspective. Unlike mainstream teamwork literature which mostly employs an etic design, an indigenous psychology perspective adopts an emic approach which places emphasis on understanding real-life phenomena in context through a cultural-insider perspective (Kim, 2000). Compatible with this theoretical position, a multiple qualitative case study approach was used as the research methodology. Three qualitative case studies were carried out in three longstanding family-run manufacturing firms in Taiwan, where family firms have been the pillars of high economic growth in the past five decades (W.-w. Chu, 2009). Two salient findings were established across the three case studies. First, the team processes identified across the three family firms are very similar with the exception of owners’ involvement and on-the-job training. All three family firms’ NPD teams are managed in a highly hierarchical manner, with considerable emphasis placed on hierarchical ranking, cost-effectiveness, efficiency, practicability, and interpersonal harmony. Second, new products developed by CFBNPD teams are mostly incremental innovation or copycat innovation, while radical or original products are rare. In many ways, CFBNPD teams may not be the ideal incubators for innovation. This is because several aspects of their unique context can cast constraints on how they work and innovate, and thus limit the ratio of radical innovation. A multi-level review into the facilitators and inhibitors of creativity or innovation in CFBNPD teams is provided. The theoretical and practical implications of the findings and the limitations of the study are also addressed.
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Hume, Chad Albert. "Platform variable identification using sensitivity analysis for product platform design." Thesis, Georgia Institute of Technology, 2013. http://hdl.handle.net/1853/50362.

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The recent trend of mass customization has redefined the way companies do business. Each individual customer is now their own market, requiring products specific to their wants and needs at mass production prices. This need for ever-increasing variety is a significant challenge for industry that many times leads to ballooning manufacturing costs and lower product performance. One approach that has received widespread attention and implementation is to develop families of products from standardized product platforms. While, many methods have been developed to address different challenges within product platform design, they are not without their limitations/tradeoffs and therefore leave much room for development and improvement. The Product Platform Constructal Theory Method (PPCTM), developed by Dr. Gabriel Hernandez, is a novel approach for developing product platforms that enable customizable products. Rooted in the tenants of hierarchic systems theory and constructal theory, the PPCTM solves for the product platform as a problem of optimization of access in a geometric space. The result is a hierarchical organization of the modes for managing variety and the specification of their commonality across the product platform. Overall, the PPCTM offers an extremely comprehensive product platform design method, with the ability to accommodate multi-platform design, multiple design specifications, non-uniform demand modeling, and multi-objective decision-making. One limitation of this method is that the selection of platform variables and the modes for managing product variety must be pre-specified or determined ad hoc by the designer. This thesis seeks to address this limitation through the integration of a sensitivity-based analysis method to determine the effect of platform variable variation on the family performance. The result of this work is a Sensitivity-based PPCTM that facilitates the selection of common platform variables, such that modes for managing variety can be ranked and applied to the space element hierarchy. The proposed method is illustrated with three examples: the design of a line of customizable pressure vessels, universal electric motors, and finger pumps.
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Osnowski, Andrew P. "Studies towards the total synthesis of the amphidinolide C family of natural products." Thesis, University of Glasgow, 2013. http://theses.gla.ac.uk/4712/.

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The amphidinolide compounds represent an extensive array of marine natural products, a number of which demonstrate potent anti-cancer bioactivity in vitro. Amphidinolide C represents an attractive synthetic target due to a combination of potent bioactivity and complex molecular architecture. This project deals with a modular and convergent total synthesis approach to amphidinolide C from which two synthetic fragments of similar size and complexity, termed ‘northern’ and ‘southern’, were synthesised in a stereoselective fashion. The stereochemical commonality between the branched chains of the 2,5-trans tetrahydrofuran systems found within both fragments, led to the conclusion that a keystone common intermediate could be applied to the synthesis of each. Previous efforts within the group have shown that 2,5-trans tetrahydrofuran-3-ones could be prepared through a diastereoselective rearrangement of a free or metal-bound oxonium ylide generated from a metal carbenoid. This thesis details the scalable preparation of the intermediate tetrahydrofuranone through tandem oxonium ylide and [2,3]-sigmatropic rearrangement. Subsequent discussions show the applicability of the intermediate to forming the C-(18)—C-(34) fragment of amphidinolide C and the C-(18)—C-(29) fragment of amphidinolide F, through the use of palladium cross-coupling methodology; alternative methods found to prepare the ‘northern’ fragment are also discussed. Additionally, the C-(1)—C-(8) fragment was prepared from the common intermediate system, the key steps in this synthesis involved introduction of the C-(4) methyl group through homogeneous catalytic hydrogenation and Luche reduction to afford the C-(7) alcohol.
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45

Kim, Jung Yoon. "The impact of platform based product variety on product family performance examining the mediational roles of new product development proficiencies and structural features /." Thesis, Online version, 2003. http://ethos.bl.uk/OrderDetails.do?did=1&uin=uk.bl.ethos.274898.

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46

Moore, Jonathan Christopher. "Studies towards the biomimetic synthesis of members of the kingianin family of natural products." Thesis, University of Nottingham, 2016. http://eprints.nottingham.ac.uk/33493/.

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47

Pineda, Palomino Dante Andrés, and Hernández Janeth Lilian Munive. "Pequeña Tribu: producto utilitario orientado a la familia." Master's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2019. http://hdl.handle.net/10757/648686.

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Pequeña tribu es una pequeña empresa que empezó a funcionar en Lima (Miraflores) hace 4 años teniendo como producto principal el Tipi (carpa india a base 4 palos de madera y tela) ya que en el mercado local no existía o no estaba visibilizado dicho producto para niños. Paula Herrera, comunicadora, diseñadora y fotógrafa, creo la empresa con la idea de contribuir al bienestar familiar reforzando los valores y el tiempo en familia. La empresa se ha mantenido con niveles bajos de producción y comercialización por la poca experiencia de gestión de la creadora. El presente trabajo tiene como finalidad comprar a Paula Herrera la marca y el concepto del negocio por un valor de S/. 10,000 y mantener la filosofía y estilo de la marca. Se ha decidido trabajar con 4 productos: Tipis, cojines, bolsos y libros. El objetivo es lograr elaborar un plan de negocio que ordene cada uno de los procesos y diferentes etapas para lograr la rentabilidad de la marca y mejorar su posicionamiento de la dentro del target, NSE A/B de Lima moderna. Pequeña tribu utilizará el e-commerce como medio para llegar a su público, vivimos en una era digital y este es el futuro inmediato de los negocios. Hemos identificado que no existen productos en el mercado local que estén orientados a la familia y al refuerzo de sus valores. Y es ahí que Pequeña tribu tiene una oportunidad de negocio. En esta era donde estamos atravesando una crisis mundial de los valores humanos es que Pequeña tribu es pertinente y necesario. Finalmente, los resultados reflejan que existe demanda para el producto y en el aspecto financiero se alcanzó un TIR del 29.90% VAN positivo de 45,137 mil soles, lo cual permite afirmar que este proyecto es rentable.<br>Pequeña Tribu is a small company that began operating in Lima (Miraflores) 4 years ago having as its main product the Tipi (Indian tent based on 4 sticks of wood and cloth) since in the local market there was no or was not visible such product for children. Paula Herrera, communicator, designer and photographer, created the company with the idea of contributing to family well-being by strengthening values and family time. The company has maintained low production and marketing levels due to the lack of management experience of the creator. The purpose of this work is to buy the brand and business concept from Paula Herrera for a value of S /. 10,000 and maintain the philosophy and style of the brand. It has been decided to work with 4 products: Tipis, cushions, bags and books. The objective is to develop a business plan that orders each of the processes and different stages to achieve the profitability of the brand and improve its positioning within the target, NSE A / B of modern Lima. Pequeña Tribu will use e-commerce as a means to reach their audience, we live in a digital era and this is the immediate future of business. We have identified that there are no products in the local market that are family oriented and reinforce their values. And it is there that Little tribe has a business opportunity. In this era where we are going through a global crisis of human values is that Small tribe is relevant and necessary. Finally, the results reflect that there is demand for the product and in the financial aspect a positive IRR of 29.29% NPV of 45,137 thousand soles was achieved, which allows to affirm that this project is profitable.<br>Tesis
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48

Cartledge, Erica Elisabeth. "Liberalisation of the Australia-Japan beef trade : its effects on family beef producers in Australia and Japan /." Title page, table of contents and introduction only, 1999. http://web4.library.adelaide.edu.au/theses/09AR/09arc327.pdf.

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49

VIEIRA, AGENILDA DAMASCENO. "THE CONSTRUCTION OF DISCURSIVE AND SOCIAL IDENTITIES REGARDING THE INTERRELATED SPEED PRODUCED BY A FAMILY FROM BRASÍLIA." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2008. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=13342@1.

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PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO<br>A presente pesquisa volta-se para o estudo da construção das identidades sociais e discursivas na fala-em-interação de uma família brasiliense. Os objetivos consistem em mostrar: como cada pessoa/participante, em seus papéis interacionais, produz sua fala/interação; como as identidades são construídas na relação entre o eu e o outro; como se articulam identidades pessoais e de grupo, no contexto da família. A fundamentação teórica articula-se entre a Sociolingüística Interacional e uma concepção sociocultural e interacional sobre identidades sociais e discursivas. A metodologia é a micro-análise etnográfica, de natureza qualitativa e interpretativa, e baseia-se em análise lingüística de interações face-a-face transcritas, bem como em entrevistas de pesquisa. A análise focaliza: o conflito interacional que se estabelece entre pai e filha em eventos interacionais; as identidades pessoais de membros da família que se constroem na relação um com o outro; as identidades de família como um grupo social. Os resultados indicam que os participantes empregam recursos que mudam os enquadres e alinhamentos familiares, criando e mantendo relações de hierarquia e solidariedade numa co-construção de suas identidades. As construções de família como grupo social se mostram em mudança, do ponto de vista das relações, mas há ainda manutenção de valores conservadores. Este trabalho propõe subsídios e resultados para que se possa refletir sobre as interações familiares, auxiliando na compreensão da construção das identidades sociais e discursivas e, principalmente, nas relações de conflito e de negociação que permeiam a família em processo de mudança.<br>The present research aims at studying the construction of discursive and social identities regarding the interrelated speech produced by a family from Brasília. The goals intended to be attained consist at showing: the way each person / participant, playing their interrelated role, produce interrelated speech; how identities are built in the relationship between the self and the other; how personal and group identities are uttered in the family context. The theoretical support resides between the Interrelated Sociolinguistics and an interrelated sociocultural conception on discursive and social identities. The methodology is the ethnographic microanalysis of qualitative and interpretative nature, and based upon linguistics analysis of face-to-face written out interactions, as well as in research interviews. The analysis focuses; the interactional conflict that is established between father and daughter in interactional events; the family members personal identities that are built in the relationship with each other; the family identities considered as a social group. The results indicate that the participants use means which change the family’s frame and footing, creating and keeping hierarchy and solidarity relationships on a co-construction of their identities. From the viewpoint of relationships, the building of a family regarded as a social group appears to be changing, though people still maintain conservative values. The present paper proposes data and results, so that one can think upon the family’s interactions, helping to compensate the construction of social and discursive identities, mainly the ones involved in the relationships of conflict and negotiations, which are part of families in process of changes.
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50

Dedeban, Vincent. "Ontology-driven and rules-based system for management and pricing of family of product." Thesis, Norwegian University of Science and Technology, Department of Computer and Information Science, 2007. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-9532.

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<p>This report presents an approach to product family management using semantic technologies. There is a need for more flexible configuration management and pricing, explicitly representing domain knowledge and configuration rules. The thesis investigates requirements, needs and current issues to support product family in order to figure out the best candidate technologies. Ontology and rules are chosen to carry out the project. Our approach is applied to a case study provided by Det Norske Veritas Software, a company offering solutions for maritime, offshore and process industries. The contacts with the company have strengthened our work as the client helped us to clarify the problem and validate the suggested method. The report discusses pros and cons of semantic technologies applied in this context. Semantic technologies and rules help to create highly flexible system that allows supporting product family engineering. Our work highlights consistency improvements and redundancy diminution in features models.</p>
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