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Dissertations / Theses on the topic 'FAR 23'

Author: Grafiati
Published: 4 June 2021
Last updated: 17 February 2022

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1

Fiala, Luboš. "Jednomotorový víceúčelový dopravní letoun v kategorii CS/FAR 23." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2013. http://www.nusl.cz/ntk/nusl-230775.

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Thesis deals with design of a single-engine aircraft. The purpose of this aircraft design is to carry up nine passengers. The work outlines technical solution of several structural elements. The design starts with aerodynamic calculations, mass analysis and concludes with calculation of flight performance and development cost estimation.
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2

Gabrlík, Jan. "Modifikace letounu EV-55 v kategorii CS/FAR 23 Commuter." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2013. http://www.nusl.cz/ntk/nusl-230957.

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This thesis deal with extended EV-55 version concept according to CS/FAR- 23 Commuter category specifications. Thesis objectives are design weights determination, mass analysis, calculation of aeroplane performances and comparison of aeroplane performances with current aeroplane.
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3

Majtán-Černák, Tomáš. "Návrh jednomotorového, víceúčelového dopravního letounu v kategorii CS/FAR 23." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2019. http://www.nusl.cz/ntk/nusl-400840.

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This diploma thesis deals with a design of single-engine, multi-purpose, transport airplane in Normal category, given by CS/FAR 23. Design is created in highest constructional and technological accordance with L 410 airplane series. Thesis determines airplanes conceptual layout, basic dimensions, basic weight and center of gravity analysis, aerodynamic and aerostatic foundation, flight performances and airplane properties. Thesis arranges various versions of cabin layouts and describes power plant installation and landing gear construction. Results of the thesis shows, that this design is advantageous in various aspects. Design is comparable with competition from perspective of its performances. Financial analysis showed, that costs of development are returnable in relatively low amount of sold airplanes, for a prices, that are lower than a prices, competition is selling similar airplanes for. Moreover, costs of maintenance are expected to be low, as a consequence of using only one engine unit.
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4

Gabrlík, Jan. "Modifikace letounu EV-55 v kategorii CS/FAR 23, Commuter." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2011. http://www.nusl.cz/ntk/nusl-374730.

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This thesis deal with extended EV-55 version concept according to CS/FAR- 23 Commuter category specifications. Thesis objectives are design weights determination, mass analysis, calculation of aeroplane performances and comparison of aeroplane performances with current aeroplane.
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5

Sokol, Filip. "Návrh kompozitového směrového kormidla pro letoun L 410 NG." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2015. http://www.nusl.cz/ntk/nusl-232083.

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This diploma thesis describes the design of composite structures rudder NG aircraft L410 based on the present Dural-weave construction. According to FAR 23 and circulars certification process is designed composite primary structure of the aircraft. It proposes the construction of a new rudder and selected materials design of a track composite materials. Program MSC Patran is this structure developed FEM model and using Nastran software Compost and the strength check.
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6

Hubáček, Jan. "Vyšetřování bezpečného únavového života křídla víceúčelového jednomotorového turbovrtulového letounu." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2021. http://www.nusl.cz/ntk/nusl-443732.

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Práce se zabývá stanovením bezpečné únavové životnosti křídla. Letadlo, které bylo podrobeno analýze, je vzpěrový hornoplošník celokovové konstrukce. Letadlo je certifikováno na základě předpisu FAR 23 Amendment 23-46. Výpočet bezpečné únavové životnosti musí být proveden v souladu s požadavky předpisu FAR 23 a jeho poradními oběžníky.\\ Teoretická část práce je věnována hlavně přehledu literatury a představení projektu, kde byla stručně shrnuta jeho historie vzniku. Část přehledu projektu také pojednává o podstatě požadavku na posouzení bezpečné únavové životnosti zadavatelem. V další části byl rovněž proveden rozbor literatury týkající se únavy. Jednalo se zejména o rozbor předpisu FAR 23, jeho poradních oběžníků a obecně literatury vztahující se k únavě jak v letectví, tak v obecném strojírenství.\\ Druhá část diplomové práce byla zaměřena zejména na výpočetní analýzu a vývoj specializovaného software. Výpočetní část obsahovala zejména přípravu vstupů, včetně obálek zatížení, stanovení typického letu, výpočet zatížení křídla a napjatostní analýza ve vybraných řezech křídla. Z výstupů prvotní analýzy se následně provedl výpočet poškození a životnosti pro daný typový let.
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7

Thomson, Amanda Mary. "A modelling approach to farm management and vegetation degradation in pre-modern Iceland." Thesis, University of Stirling, 2003. http://hdl.handle.net/1893/23.

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Grazing by domestic livestock is one of the primary ways by which humans have modified landscapes. At low stocking rates livestock grazing can modify vegetation community composition, but at high stocking rates grazing can also reduce vegetation productivity and initiate soil erosion, leading to land degradation. The country of Iceland has undergone severe land degradation over the past 1100 years, with over half of the former vegetation cover being lost, and the remainder having depleted productivity. This work focuses upon the role that grazing by domestic livestock played in this degradation, and how the interactions between farm management, vegetation cover and climate affected grazing patterns in space and time. The aims of the research were achieved by constructing an environmental simulation model, called Búmodel, which allowed a cross-disciplinary approach that integrated landscape ecology, environmental archaeology and historical analysis. Búmodel was loosely coupled with GIS so that spatially based model inputs and outputs could be displayed and analysed in map form. The purpose of Búmodel was to predict spatial and temporal patterns of vegetation biomass production and utilisation (through grazing and hay-making) with a view to commenting on vegetation degradation in the pre-modern period (pre-1900 AD). The model was parameterised using contemporary and historical Icelandic agricultural data. Model validation was undertaken using sensitivity tests and comparison with data from an independent grazing experiment in the north of Iceland. Búmodel was then applied to two contrasting study areas: Vestur- Eyjafjallahreppur, a farming community on the south coast of Iceland, and Hofstaðir, a farm estate in the north east of the country, situated inland by Lake Mývatn. These applications demonstrated the importance of farm management in avoiding land degradation and in ameliorating the impact of climate. They also established the usefulness of Búmodel as a tool for the investigation of human and environmental interactions in Iceland.
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8

Mirza, Majd A. I. "The role of fibroblast growth factor-23 in chronic kidney disease-mineral and bone disorder." Doctoral thesis, Uppsala universitet, Medicin, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-130339.

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Fibroblast growth factor-23 (FGF23) was initially identified as the causative factor of autosomal dominant hypophosphatemic rickets. Further studies confirmed that FGF23 is predominantly expressed in the osteocytes and osteoblasts of bone and that circulating FGF23 acts on the kidney to inhibit renal phosphate reabsorption and 1,25(OH)2D3 hydroxylation. With the progression of chronic kidney disease (CKD), the kidneys become insufficient to maintain a normal systemic mineral homeostasis, resulting in various abnormalities of bone and mineral metabolism, generally referred to as Chronic Kidney Disease – Mineral and Bone Disorders (CKD-MBD). FGF23 increases early in the course of CKD in order to maintain normal serum phosphate levels; long before a significant increase in serum phosphate can be detected. Recent studies suggest that increased FGF23 levels are associated with progression of CKD, mortality, and the development of refractory secondary hyperparathyroidism. Because FGF23 is the very earliest marker of CKD-MBD, it is of particular interest to evaluate the relation between FGF23 and CKD-MBD abnormalities, in the setting of early CKD and also in individuals with normal renal function. In the present work, we show that FGF23 is linked to several dynamic measurements of vascular function, including endothelial dysfunction, arterial stiffness, and atherosclerosis. FGF23 is also positively associated with left ventricular mass index and an increased risk of having left ventricular hypertrophy. All associations were independent of serum phosphate and were strengthened in subjects with diminished renal function. Furthermore, we found significant evidence for an association between higher FGF23 and increased fat mass and dyslipidemia, which could represent a novel pathway linking FGF23 to cardiovascular disease. Finally, we show that FGF23 is a significant predictor of future fracture risk. Although these associations could be reflecting the increased risk associated with hyperphosphatemia and calcitriol deficiency, current evidence points towards FGF23 being more than an innocent bystander. At the very least, FGF23 holds promise of being a bio-marker of cardiovascular status and phosphate-related toxicity both in CKD and in the general population, and might be a therapeutic target that could improve the fatal prognosis in CKD patients.
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9

Duvallet, Emilie. "Etude dans l’arthrite expérimentale au collagène de stratégies d’immunothérapies actives ciblant : l’interleukine-23, le vascular endothelial growth factor et le tumor-necrosis factor-α." Paris 13, 2012. http://scbd-sto.univ-paris13.fr/intranet/edgalilee_th_2012_duvallet.pdf.

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La polyarthrite rhumatoïde (PR) est le rhumatisme inflammatoire le plus fréquent. Des immunothérapies passives utilisées pour le traitement de la PR, ciblent principalement les cytokines pro-inflammatoires majeures dans la PR. Ces traitements sont efficaces mais présentent de nombreux inconvénients (coût, perte d’efficacité, infections et cancers), ce qui laisse la place pour le développement d’une stratégie vaccinale anti-cytokine. Notre travail s’est organisé en trois axes : - Cibler spécifiquement la cytokine pro-inflammatoire interleukine-23 par une approche vaccinale et rechercher les mécanismes impliqués dans l’amélioration des arthrites. - Cibler l’angiogenèse pathologique par une approche vaccinale anti-peptide du VEGF. - Etudier la faisabilité et la sécurité de la vaccination anti-TNF lorsqu’elle est coadministrée avec des immunosuppresseurs. Nos résultats ont montré que bien que l’inhibition des arthrites ne soit que partielle, la vaccination dirigée contre l’IL-23 ou le VEGF permet de moduler les arthrites au niveau clinique, tout en diminuant nettement l’inflammation et la destruction ostéo-articulaire au niveau histologique. De plus, l’utilisation combinée d’immunosuppresseurs avec un vaccin anti-TNF ne diminue pas l’efficacité de ce dernier. Enfin, il est intéressant de noter que l’utilisation de forte dose de cyclophosphamide neutralise l’action du vaccin. Ainsi nous montrons que le VEGF et l’IL-23 sont de bonnes cibles thérapeutiques potentielles dans l’arthrite et que l’approche vaccinale est compatible avec le maintien d’un traitement de fond par des immunosuppresseurs
Rheumatoid arthritis (RA) is the most frequent inflammatory rheumatism. Passive immunotherapies used for the treatment of RA, mainly target the main pro-inflammatory cytokines in RA. These therapies are efficient but possess many drawbacks (cost, loss of efficacy, infections, and cancers), which lives some room for the development of a strategy by anti-cytokine vaccination. Our work was organized into three axes: - Specifically target the pro-inflammatory cytokine interleukine-23 through vaccination and look for the mechanisms implied in the arthritis decrease. - Target the pathological angiogenesis through a peptide-based anti-VEGF vaccination. - Study feasibility and safety of the anti-TNF vaccination when it is coadministered with immunosuppressive drugs. Our results showed that even of arthritis inhibition is partial, vaccination against IL-23 or VEGF can modulate arthritis at the clinical level while distinctly decreasing inflammation and osteo-articular destruction at the histological level. Additionally, the combined use of immunosuppressive drug with an anti-TNF vaccin does not decrease its efficiency. To finish, it is interresting to note that use an elevated dose of cyclophosphamide neutralize the vaccin’s action. So we show that VEGF and IL-23 are potential therapeutic targets in arthritis and that vaccination is compatible with maintenance of disease-modifying drugs as immunosuppressive drugs
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10

Pompilian, Mariette. "La contraction musculaire et les transformations de l'énergie thèse pour le doctorat en médecine présentée et soutenue le 23 juillet 1897 /." Paris : BIUM, 2003. http://www.bium.univ-paris5.fr/histmed/medica/cote?TPAR1897x622.

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11

Nélaton, Auguste. "Recherches sur l'affection tuberculeuse des os thèse présentée et soutenue à la Faculté de Médecine de Paris le 23 décembre 1836... /." Paris : BIUM, 2003. http://www.bium.univ-paris5.fr/histmed/medica/cote?TPAR1836x376.

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12

Jacobi-Putnam, Mary Corinna. "De la graisse neutre et des acides gras thèse pour le doctorat en médecine présentée et soutenue le 23 juillet 1871 /." Paris : BIUM, 2003. http://www.bium.univ-paris5.fr/histmed/medica/cote?TPAR1871x033.

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13

Dylion, Berta. "De l'insertion vicieuse du placenta : essai de clinique thérapeutique Thèse pour le doctorat en médecine présentée et soutenue le 23 juillet 1890 /." Paris : BIUM, 2003. http://www.bium.univ-paris5.fr/histmed/medica/cote?TPAR1890x335.

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14

Richet, Charles. "Recherches expérimentales et cliniques sur la sensibilité thèse présentée et soutenue à la Faculté de médecine de Paris le 23 janvier 1877 /." Paris : BIUM, 2003. http://www.bium.univ-paris5.fr/histmed/medica/cote?TPAR1877x069.

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15

Santos, Endrigo Sperto Rodrigues dos. "Correlação entre doença aterosclerótica, dieta hipercolesterolêmica e as perdas dentais, estudo em modelo animal." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/23/23147/tde-28042009-095027/.

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O objetivo deste trabalho foi de avaliar em Modelo animal, coelhos (raça Nova Zelândia) divididos em três grupos randomizados, (jovem com 60 dias (G1), um idoso com aterosclerose e ingestão de colesterol (G2) e um idoso com aterosclerose e sem ingestão do colesterol (G3)) se, a dieta rica em colesterol e a idade, causam lesões de aterosclerose e placas ateroscleróticas nos animais, alterações nos comprimentos dos dentes, aumento ou diminuição dos espaços periapicais dos dentes, perda óssea alveolar na maxila e mandíbula. Através da metodologia descrita e após as análises histológicas e morfológicas, verificou-se diferença estatisticamente significante, nas variáveis dos comprimentos dos dentes 1º prémolares superiores entre os grupos G3 versus G1 p<5%. médias de 1247,88 (p=0,017) e G3 versus G2, com diferença das médias de 1190,85 (p=0,025) ou seja o comprimento dos dentes fora diferente no grupo G2. Com relação à variável, espessura do osso alveolar, não ocorreu significância estatística, porém tendências de que este esteja sendo alterado. Com relação a variável espessura do espaço periapical fora verificado significância estatística com p=0,017 em relação ao G1, na região dos 1º Pré-molares, apresentando a diferença das médias (403,42) a favor do G2, ou seja aumento do espaço periapical. A variável da área de placa de aterosclerose, correlacionada, com os comprimentos dos dentes e espessura do osso alveolar, também teve resultado significante na região 1º e 2º pré-molares entre G2 e G3. com p=0,025 e r=0,476. Confirmando assim a correlação da aterosclerose, dietas hiperclesterolêmicas e as alterações da cavidade bucal e estrutura de sustentação dos dentes.
The aim of this study is, to evaluate on animal model (New Zealand rabbits), on different and randomized groups (G1 a young group, G2 an older rabbit, with atherosclerosis and ingesting hipercholesterolemic fat diet and another group G3, just an older group) investigated than the hipercholesterolemic fat diet induced atherosclerotic lesions and plaques in ascendant aorta, bone loss in maxillary and jaw, alterations on length of the tooth, alterations on tooth periapical spaces. By the methodology described and aplicated, before the histological and morphological analysis, was verified significant statistical variance in the length of the first premolar tooth and second premolar on maxillary region, the length of this tooth is reduced in G2 (p<5%). The medias are 1247,88 (p=0,017) and 1190,85 (p=0,025). Analyzing another variable on the alveolar bone thickness, was not found any statistical significance, but tendencies that this event may occur. According to another variable of the thickness found on the periapical space, it was verified a significant variable statistic such as p=0,017 related on G1, on first premolar region, suggesting a different statistic, between medias, favoring G2 meaning the increase of periapical space. The variable on the atherosclerosis plaque area, related to the teeth length and alveolar bone thickness, also showed significant results on first and second premolars regions between G2 and G3, with p=0,025 and r=0,476. That confirms the atherosclerosis correlations and hipercholestrolemic fat diet, also alterations in oral cavity and teeth implantation structure.
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16

Edwards-Pilliet, Blanche. "De l'hémiplégie dans quelques affections nerveuses (ataxie locomotrice progressive, sclérose en plaques, hystérie, paralysie agitante) Thèse pour le doctorat en médecine présentée et soutenue le 23 janvier 1889 /." Paris : BIUM, 2003. http://www.bium.univ-paris5.fr/histmed/medica/cote?TPAR1889x111.

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17

Khalij, Leila Hariri Saïd Vaucher Rachel. "Détermination directe des états limites et des champs de contraintes résiduelles pour les structures chargées cycliquement application de la méthode d'analyse simplifiée /." [S.l.] : [s.n.], 2002. http://www.univ-lille1.fr/bustl-grisemine/pdf/extheses/50376-2002-23-24.pdf.

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18

Larsson, Mona. "STRAFFRÄTTSLIG PLIKT ATT BISTÅ NÖDSTÄLLD : En analys med huvudfokus på Norges lagstadgade plikt att bistå nödställd samt på Sveriges reglering angående medhjälp till självmord." Thesis, Örebro universitet, Akademin för juridik, psykologi och socialt arbete, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-13758.

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SAMMANFATTNING   Sverige har ännu ingen straffrättslig plikt att bistå nödställd som en del andra nordiska länder har. Genom ett dagsaktuellt direktiv har det begärts att eventuella följder vid ett införande av en sådan plikt skall utredas. Plikten är uppsatsens huvudämne och det ämnas redogöra för konsekvenser av ett eventuellt framtida införande av denna plikt.   Historiskt sett har ett flertal motioner lämnats om införande av plikt att bistå nödställd. Kritik handlar om att det är straffritt att se på utan att ingripa då andra till följd av olyckor eller brott hamnat i nöd. Motionerna har varje gång efterföljts av avslag. Grunden till detta baserar sig huvudsakligen på problem med lagens allmänna ordalydelse där det skulle bli svårt för allmänheten att förutse vad som är tillräcklig hjälp och inte. Sådan plikt ansågs också överflödig dels på grund av att Sverige har flertalet specialbestämmelser med påbud om ingripande men även för att allmänheten ser det som en moralisk plikt att hjälpa nödställda.   Då området för konsekvenserna är oöverskådligt har jag valt att fokusera på två huvudproblem som grund till frågeställningarna. Den första frågan är om Norges lagstadgade plikt i § 387 NSL är en god förebild för Sverige vid utformning av bestämmelsens ordalydelse och tillämpning av densamma?   Den andra frågan rör medhjälp till självmord som är straffritt i Sverige. Kan detta straffria område komma att påverkas rent straffrättsligt vid införande av plikt att bistå nödställd?   För att besvara dessa frågor har en i huvudsak rättsdogmatisk metod med komparativa inslag valts. Då Norges stadgande ligger till grund för en av frågeställningarna är det naturligt att huvudfokus ligger på detta grannland.   Vid äkta underlåtenhetsbrott är det uttryckligen underlåtenhet att vidtaga en påbjuden handling som är den straffbelagda gärningen. Oäkta underlåtenhetsbrott kriminaliserar en underlåtenhet som är kausal till uppkommen effekt. Dock måste gärningsmannen befinna sig i garantställning för att straffansvar skall kunna utkrävas vid detta brott. Handlingsplikten kan uppstå genom åligganden i lag, avtal eller eget föregående handlande. Det sistnämnda innebär att gärningsmannen själv framkallat en viss fara som resulterat i en effekt, det vill säga skada av något slag, där garanten bestraffas för underlåtenhet att avvärja denna effekt.   Norges § 387 NSL är utformad som ett äkta underlåtenhetsbrott, men uttryckligen i lagtexten stadgas att för det fall den nödställde omkommer utdöms ett högre fängelsestraff än om denne överlever. I praktiken tillämpas stadgandet som om det vore ett oäkta underlåtenhetsbrott där den underlåtande straffas för uppkommen effekt. Tidigare nämndes att i svensk rätt sker detta endast vid oäkta underlåtenhetsbrott där gärningsmannen är garant. Slutsatsen tillhörande den första frågeställningen är att Norges stadgande inte bör ses på som en god förebild vid ett eventuellt införande av hjälpplikt då allmänheten indirekt hamnar i garantställning och straffas i enlighet därmed.   Den andra frågeställningen gällande huruvida den straffria medhjälpen till självmord kan komma att påverkas av nämnda plikt besvaras jakande. Den som försöker begå självmord är i nöd. När medhjälparen underlåter att rädda den nödställdes liv kan denne dömas för underlåtenhet att bistå nödställd. Hur denna problematik för svensk del skall hanteras förtäljer inte historien.
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19

Monyakane, ’Mampolokeng ’Mathuso Mary-Elizabeth. "The constitutionality of employers' investigative procedures and disciplinary hearing processes with specific reference to dismissal of employees on the basis of criminal misconducts in South Africa." Thesis, 2020. http://hdl.handle.net/10500/26956.

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This Doctoral thesis entitled the Constitutionality of Employers' Investigative Procedures and Disciplinary Hearing Processes with Specific Reference to Dismissal of Employees on the Basis of Criminal Misconducts in South Africa, focusses on individual labour law principles of fair labour practices entrenched in section 23(1) of the Constitution. The thesis deals with fairness in situation where an employee who is suspected of committing a criminal act is investigated and subsequently goes through a disciplinary hearing for dismissal. It determines the extent to which an employee’s criminal guilt is decided before dismissal. As such, the thesis is based upon South African judicial interpretation of the right to fair dismissal. In the process the thesis examines the application of principles informing the employer’s duty to provide fair reason concerning the dismissal of employees criminal suspects. In examining if employers observe constitutional transformative objective when conducting criminal investigations and disciplinary hearings - the thesis reviews the extent to which the employer respects constitutional rationales of equity based on the principles of natural justice. These natural justice principles are the basis upon which section 23(1) fairness is founded. Section 23 (1) is implemented through the LRA provisions. The thesis then concludes that, only one principle of natural justice - audi alteram partem is respected within employer flexibility-based fairness while the other principle - nemo judex in propria sua causa is ignored. It is this denial that causes serious procedural challenges in the quest for equity intended in section 23(1) fair labour practices. It is upon these foundational equity concerns that this thesis opposes the flexibility in employer’s criminal investigations and disciplinary hearing processes entrenched in item 4 (1) of Schedule 8 of the LRA fair procedure for dismissal of employees suspected of criminal acts. The thesis interlinks labour law and criminal law to advocate for the missing constitutionally justiciable fairness for employees who have committed criminal misconducts. It argues that the current judicial interpretation of labour law fairness is based upon the principle of flexibility underlying dismissals, asserting that fairness based on flexibility breeds informal procedural processes which exempt employers from observing crucial constitutional fairness principles expressed through proportionality-based prescripts. The thesis concludes that the practice of including the right against self-incrimination in employment law, done in other common law countries be introduced into the South African labour law through section 39 of the Constitution so that the identified procedural challenges are regulated.
Mercantile Law
LL.D.
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