Journal articles: 'Farinae'

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Okamoto, Kiku. "Aggregative Behaviour of Dermatophagodes farinae." Medical Entomology and Zoology 50, no. 2 (1999): 196. http://dx.doi.org/10.7601/mez.50.196_3.

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Cui, Yubao, Cuixiang Gao, Ying Zhou, Peng Zhou, Ming Peng, Yingzi Lin, and Jianglong Peng. "Phylogenetic analysis of house dust mites." Open Medicine 5, no. 1 (February 1, 2010): 69–74. http://dx.doi.org/10.2478/s11536-009-0106-6.

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AbstractHouse dust mites live in house dusts and affect the health of humans. Among the many species, Dermatophagoides farinae, D. pteronyssinus, and Euroglyphus maynei have been found to be commonly associated with Ig-E-mediated allergic diseases. As a result, there is increasing effort to develop methods for the diagnosis and treatment of diseases caused by these species. The purpose of the current study was to explore the evolutionary relationships among house dust mites. After adult D. farinae were separated and isolated for total RNA extract, the cDNA coding for Der f 1 and Der f 2 were cloned and sequenced. Then amino acid sequences for group 1 and 2 allergens of two of the most common house dust mites, D. pteronyssinus, E. maynei, were obtained from databases. Interestingly, homological analysis of amino acid sequences showed that both Der p 1 and Der p 2 from D. pteronyssinus had more similarities to Eur m 1 and Eur m 2, respectively, than they had to Der f 1 and Der f 2 from D. farinae. In the phylogenetic trees, D. pteronyssinus clustered with E. maynei, but not with D. farinae, although D. pteronyssinus and D. farinae belong to the same genus according to morphological taxonomy. It was previously assumed that D. pteronyssinus was more similar to E. maynei than to D. farinae at evolutionary levels.

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ZEYTUN, Erhan, Salih DOĞAN, Edhem Ünver, and Fatih ÖZÇÜÇEK. "Evaluation of Dermatophagoides pteronyssinus (Trouessart) and D. farinae Hughes (Acari: Pyroglyphidae) sensitivity in patients with allergic rhinitis: a comparative study." Systematic and Applied Acarology 23, no. 2 (February 7, 2018): 206. http://dx.doi.org/10.11158/saa.23.2.2.

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This study was conducted to determine the sensitivity to Dermatophagoides pteronyssinus (Trouessart) and D. farinae Hughes with skin prick tests (SPT) and serologic tests in patients with allergic rhinitis (AR), and to specifically search for those mites in homes of patients. A total of 51 participants, (23 patients and 28 controls) were utilized. Skin-prick tests with D. pteronyssinus and D. farinae allergens were performed on all participants, and serum levels of allergen-specific lgE and total IgE were also measured. Dust samples were collected from homes of all participants and examined under a stereo microscope. 977 D. pteronyssinus (mean 44.4/g) and 24 D. farinae (mean 4.0/g) were isolated from the homes of patients, whereas 35 D. pteronyssinus (mean 4.4/g), and four D. farinae (mean 2.0/g) were isolated from the homes of the controls. Patients with D. pteronyssinus in their homes had 95.5% sensitivity to the species according to SPT and 27.3 according to IgE. Patients with D. farinae in their homes had 83.3% sensitivity to the species according to SPT, and 50% according to IgE. Dermatophagoides pteronyssinus sensitivity in the controls was detected as 12.5% according to SPT; however, D. farinae sensitivity was not detected according to both SPT and mite-specific IgE. Differences between patients and controls utilizing SPT results was statistically significant, but not when using mite-specific IgE results. As a result, it was determined that patients with AR in Erzincan province were sensitized to D. pteronyssinus and D. farinae, and that their homes contained those species. It may be helpful to consider these findings in clinical assessment of patients with AR, and also in treatment utilizing immunotherapy techniques.

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Molva, Vit, Marta Nesvorna, and Jan Hubert. "Feeding Interactions Between Microorganisms and the House Dust Mites Dermatophagoides pteronyssinus and Dermatophagoides farinae (Astigmata: Pyroglyphidae)." Journal of Medical Entomology 56, no. 6 (May 30, 2019): 1669–77. http://dx.doi.org/10.1093/jme/tjz089.

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Abstract The feeding interactions between house dust mites (HDM) and microorganisms are key factors in the survival of mites in human environments. The suitability of different microbes for HDM is not known. Here, microbial species isolated from HDM cultures were offered to HDM in food preference tests under laboratory conditions. The microbial species were added to the rearing diet of mites to reach 7% of Saccharomyces cerevisiae and 10% of each tested microorganism. The suitability of each microbe-supplemented diet for Dermatophagoides pteronyssinus and Dermatophagoides farinae was compared in terms of mite population growth and mite preference in a cafeteria test. The effect of mite feeding on the respiration of microorganisms in the diet was observed in microcosms. HDM were able to feed and reproduce on some bacterial and fungal species, but the suitability of microbial species differed. Increasing the yeast Sa. cerevisiae in the diet from 7 to 17% appeared the most suitable for both mite species. Staphylococcus spp. bacteria were preferred for D. farinae and were suitable for reproduction. The population growth and feeding preferences of D. pteronyssinus and D. farinae with respect to microorganisms indicate that D. farinae can develop on a diet with bacterial (Staphylococcus nepalensis and Staphylococcus kloosii) additions, whereas D. pteronyssinus was successful on a diet with fungal (Aspergillus jensenii and Aspergillus ruber) additions. The bacteria Kocuria rhizophila and Bacillus cereus decreased population growth in D. pteronyssinus, whereas the yeasts Hyphopichia pseudoburtonii, Hyphopichia burtonii, and Candida ciferrii decreased population growth in D. farinae. These results indicate that some microorganisms are an important food source for HDM.

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Dhaliwal, Amandeep Kaur, Devinder Singh, Ramanpreet Kaur Randhawa, and Atinderpal Singh. "Sensitivity in allergic asthmatic subjects towards house dust mite allergens." Systematic and Applied Acarology 26, no. 1 (January 6, 2021): 75–84. http://dx.doi.org/10.11158/saa.26.1.5.

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Asthma is a common problem that affects about 20 million peoples in India and can be often under-diagnosed or misdiagnosed. It can be allergic or non-allergic though the former type is more common and prevalent. Allergic asthma can be triggered by many allergens and house dust mites (HDM) are one of the common indoor allergens. The present study emphasizes the significance of house dust mites in allergic asthmatic subjects which is based on 115 asthmatic subjects in Punjab, India. For the quantification and the estimation of total serum Immunoglobulin E and HDM specific IgE, a mixture of 14 allergens and a mixture of two mite allergens viz. Dermatophagoides pteronyssinus and D. farinae were used respectively. Total and specific IgE levels were detected on ImmunoCAP Phadia 100. A statistically significant correlation between total and HDM specific IgE levels of 115 asthmatic subjects was found as compared to control group of 30 non-allergic individuals. The specific IgE levels of 54.78% subjects against the allergen of two mite species were found to be positive. Dust samples were taken from various localities of the houses to identify the diversity of house dust mites which were responsible for allergic asthma. Five common house dust mite species viz. D. pteronyssinus Trouessart, D. farinae Hughes, D. microceras Griffiths and Cunnington, D. aureliani Fain and Euroglyphus maynei Cooreman were identified from the dust. The present study observed that total IgE levels were higher with higher specific IgE levels against the mixture of two mite allergens viz. D. pteronyssinus and D. farinae in the blood serum. D. pteronyssinus was the most abundant and prevalent mite species followed by D. farinae. Therefore, present study concluded that HDM specific IgE levels against the mite allergen of D. pteronyssinus and D. farinae in the serum of allergic asthmatic subjects were found to be higher because of the higher prevalence of these two mites (D. pteronyssinus i.e. 69.80% and D. farinae i.e. 20.72%) in the house of allergic asthmatic subjects as compared to other identified mites.

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Sung, Yoon-Young, and Ho Kim. "Crocin Ameliorates Atopic Dermatitis Symptoms by down Regulation of Th2 Response via Blocking of NF-κB/STAT6 Signaling Pathways in Mice." Nutrients 10, no. 11 (November 2, 2018): 1625. http://dx.doi.org/10.3390/nu10111625.

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Crocin, a major constituent of Gardenia jasminoides, is a natural colorant carotenoid compound that has been reported to have anti-inflammatory effects. This study investigated the therapeutic effects of crocin on mice with atopic dermatitis induced by Dermatophagoides farinae crude extract, which is a common environmental allergen in house dust that causes atopic dermatitis in humans. Crocin application ameliorated Dermatophagoides farinae crude extract-induced atopic dermatitis symptoms by inhibiting the dermatitis severity score, ear thickness, and serum immunoglobulin E levels in NC/Nga mice. The increases in epidermal thickness and dermal inflammatory cells (eosinophil and mast cells) infiltrations observed on the dorsal back skin of atopic dermatitis control mice were inhibited in a dose-dependent manner by topical application of crocin in atopic dermatitis treatment mice. Crocin inhibited the Dermatophagoides farinae crude extract-induced increase of thymus and activation-regulated chemokines, interleukin (IL)-4, and IL-13 on the dorsal skin of mice. Crocin also inhibited Dermatophagoides farinae crude extract-induced activation of nuclear factor-κB (NF-κB) and signal transducer and activator of transcription (STAT) 6. These results show that crocin ameliorates atopic dermatitis symptoms by down regulation of the Th2 cells-mediated immune response via blocking of NF-κB/STAT6 signaling pathways.

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7

Hashimoto, T., K. Minagawa, K. Mizutani, and N. Motoyama. "Susceptibility of Dermatophagoides farinae to several agents." Medical Entomology and Zoology 50, no. 2 (1999): 187. http://dx.doi.org/10.7601/mez.50.187_1.

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8

Duez, Catherine, Barbara Gross, Philippe Marquillies, Valérie Ledroit, Bernhard Ryffel, and Corine Glineur. "Regulation of IL (Interleukin)-33 Production in Endothelial Cells via Kinase Activation and Fas/CD95 Upregulation." Arteriosclerosis, Thrombosis, and Vascular Biology 40, no. 11 (November 2020): 2619–31. http://dx.doi.org/10.1161/atvbaha.120.314832.

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Objective: The occurrence of new blood vessel formation in the lungs of asthmatic patients suggests a critical role for airway endothelial cells (ECs) in the disease. IL-33 (Interleukin-33)—a cytokine abundantly expressed in human lung ECs—recently emerged as a key factor in the development of allergic diseases, including asthma. In the present study, we evaluated whether mouse and human ECs exposed to the common Dermatophagoides farinae allergen produce IL-33 and characterized the activated signaling pathways. Approach and Results: Mouse primary lung ECs were exposed in vitro to D farinae extract or rmIL-33 (recombinant murine IL-33). Both D farinae and rmIL-33 induced Il-33 transcription without increasing the IL-33 production and upregulated the expression of its receptor, as well as genes involved in angiogenesis and the regulation of immune responses. In particular, D farinae and rmIL-33 upregulated Fas/Cd95 transcript level, yet without promoting apoptosis. Inhibition of caspases involved in the Fas signaling pathway, increased IL-33 protein level in ECs, suggesting that Fas may decrease IL-33 level through caspase-8-dependent mechanisms. Our data also showed that the NF-κB (nuclear factor-κB), PI3K/Akt, and Wnt/β-catenin pathways regulate Il-33 transcription in both mouse and human primary ECs. Conclusions: Herein, we described a new mechanism involved in the control of IL-33 production in lung ECs exposed to allergens.

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9

Naz, Shumaila, Farhana Riaz Chaudhry, Dilawar Abbas Rizvi, and Muhammad Ismail. "Phylogenetic Analysis of Astigmatid Mites Sarcoptes scabiei and Dermatophagoides farinae using ITS-2 as a Genetic Marker." Life and Science 1, no. 2 (April 14, 2020): 5. http://dx.doi.org/10.37185/lns.1.1.75.

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Objective: The coding of astigmatid mites based on their morphological and developmental characteristics often leads to uncertainty in the results. The ribosomal internal transcribed spacer (ITS-2) region, being highly conserved in eukaryotes is commonly employed as a barcode for identification of mite species. The present study was an attempt to characterize the gene sequences of astigmatid mites i.e. Sarcoptes scabiei (S. scabiei), Dermatophagoides farinae (D. farinae) using ITS-2 as a genetic marker. Place and Duration of Study: The study was conducted at Department of Dermatology, Military Hospital (MH), Rawalpindi from September 2012 to October 2013. Materials and Methods: In order to characterize relationship of astigmatid mites, the ITS-2 marker was successfully amplified and sequenced. The resulting ITS-2 gene sequences were aligned using Clustal W. MEGA 7 was used to construct phylogenetic tree of the aligned sequence. Results: The phylogenetic tree showed an overall genetic distance of 0.53 indicating close genetic relationship among astigmatid mite species. Pairwise distance was calculated for the ITS-2 gene and low genetic diversity values were observed within S. scabiei and D. farinae that range from 0.003-0.008 and 0.006-0.038 respectively. Conclusion: The study supports the view that the ITS-2 region can be used to identify morphologically difficult astigmatid mites but is not useful in characterization of different species based on the geographical distribution. This study has important implication in our understanding of the epidemiology of S. scabiei and D. farinae and development of control strategies in human transmission.

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10

Masaki, Katsunori, Koichi Fukunaga, Yuji Kawakami, and Rubaiyat Haque. "Rare presentation of anaphylaxis: pancake syndrome." BMJ Case Reports 12, no. 3 (March 2019): e228854. http://dx.doi.org/10.1136/bcr-2018-228854.

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A 43-year-old woman presented with oral discomfort, sneezing, urticaria, eyelid angioedema, abdominal pain, diarrhoea, dyspnoea and wheeze soon after eating a Japanese flour pancake (okonomiyaki, containing wheat, egg, yam, pork, prawn and squid). Subsequent analysis of the flour used in the pancake revealed the presence of Dermatophagoides farinae (4500 mites/g). The patient tested positive for specific IgE to D. farinae (15.2 kU/L) and D. pteronyssinus (14.0 kU/L) with negative responses to other ingredients in the pancake. Oral ingestion of dust mite in poorly stored foods can cause anaphylactic reactions in patients with allergy.

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11

Arlian, Larry G., and Jacqueline S. Dippold. "Development and Fecundity of Dermatophagoides farinae (Acari: Pyroglyphidae)." Journal of Medical Entomology 33, no. 2 (March 1, 1996): 257–60. http://dx.doi.org/10.1093/jmedent/33.2.257.

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12

Dixit, A., R. D. Lewis, K. Ong, D. A. Backer, and M. MacDonald. "Interaction of fungi with dust mite Dermatophagoides farinae." Journal of Allergy and Clinical Immunology 115, no. 2 (February 2005): S98. http://dx.doi.org/10.1016/j.jaci.2004.12.404.

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13

Cunha, Victor E. S., Maria Helena Silva, and João Luiz H. Faccini. "Serological identification of house dust mite allergens in dogs with atopic dermatitis." Pesquisa Veterinária Brasileira 32, no. 9 (September 2012): 917–21. http://dx.doi.org/10.1590/s0100-736x2012000900016.

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House dust mite antigens have been used for decades to diagnose allergic diseases in humans and animals. The objective of this study was to identify allergens in commercial Dermatophagoides farinae and Blomia tropicalis extracts by immunoblotting using sera from allergic dogs and anti-dog IgE conjugate. The analysis of antigens present in the D. farinae extract (FDA Allergenic) using sera from 10 dogs allergic to D. farinae showed that eight sera recognized a band of approximately 102 kDa, eight recognized two bands of 52 to 76 kDa, five recognized one band of approximately 76 kDa, four recognized one band of 31 to 38 kDa, and two recognized one band of 12 to 17 kDa. Immunoblot assays of the B. tropicalis extract (FDA Allergenic) using sera from 10 animals allergic to B. tropicalis showed that five sera recognized two bands of 52 to 76 kDa. These results demonstrate the importance of the two house dust mite species for the pathogenesis of canine atopic dermatitis in Brazil. In addition, the results indicate which allergens should be present in allergenic extracts used for diagnosis and allergen-specific immunotherapy.

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14

Jeong, Y., T. Yun, H. Kim, Y. Koo, JH Kang, MP Yang, and BT Kang. "Induction of atopic dermatitis by epicutaneous sensitisation with Dermatophagoides farinae in nongenetically predisposed Beagle dogs." Veterinární Medicína 66, No. 10 (September 8, 2021): 413–22. http://dx.doi.org/10.17221/58/2020-vetmed.

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This study was performed to induce atopic dermatitis (AD) using nongenetically predisposed Beagle dogs. Five healthy Beagle dogs were used. Twice weekly for 12 weeks, the dogs were painted on the axillae and groin with a solution of Dermatophagoides farinae (D. farinae). Each dog was thereafter placed in a cage where a house dust mite (HDM) solution was applied on the bottom of the cage. The dog remained in the cage for 3 h daily for 3 consecutive days for the environmental exposure to HDM. Serum samples were collected at 0 week and 6 weeks after sensitisation, and at 0 h and 72 h after the environmental exposure. During the environmental exposure, skin biopsies were obtained at 0 h, 36 h, and 72 hours. After the first environmental exposure, no dog had any marked clinical sign. An additional sensitisation was subsequently administered for 10–13 weeks. Three of the five dogs developed pruritic dermatitis with skin lesions after the second exposure. The histopathology of the lesions revealed severe infiltration of inflammatory cells and dermal oedema. The levels of D. farinae-specific IgE were also elevated. This study demonstrated that AD could be induced by epicutaneous sensitisation with HDM in nongenetically predisposed dogs.

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Kreil-Ouschan, Claudia. "Management der felinen atopischen Dermatitis." kleintier konkret 20, no. 06 (December 2017): 32–34. http://dx.doi.org/10.1055/s-0043-120729.

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Die feline Atopie ist eine Überempfindlichkeitsreaktion gegenüber Umweltallergenen (Hausstaubmilben, Vorratsmilben, Gräser-, Kräuter- und Baumpollen). Hausstaubmilben, insbesondere Dermatophagoides farinae, gehören zu den häufigsten Auslösern bei der Katze.

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16

Tajima, Kimio. "DETECTION OF LIMULUS POSITIVE SUBSTANCES IN DERMATOPHAGOIDES FARINAE EXTRACTS." Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology 2, no. 1 (1988): 49–51. http://dx.doi.org/10.3388/jspaci.2.49.

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17

Yamakawa, H., Y. Ino, and M. Iwaki. "Immunopharmacological study of spontaneously sensitized dog with dermatophagoides farinae." European Journal of Pharmacology 183, no. 3 (July 1990): 893. http://dx.doi.org/10.1016/0014-2999(90)92720-4.

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18

Jamora, Maria Jasmin J., Vermén M. Verallo-Rowell, and Maria Teresa Y. Samson-Veneracion. "Patch Testing With 20% Dermatophagoides pteronyssinus/farinae (Chemotechnique) Antigen." Dermatitis 12, no. 2 (June 2001): 67–71. http://dx.doi.org/10.1097/01206501-200106000-00001.

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Jamora, Maria Jasmin J., Vermén M. Verallo-Rowell, and Maria Teresa Y. Samson-Veneracion. "Patch Testing With 20% Dermatophagoides pteronyssinus/farinae (Chemotechnique) Antigen." American Journal of Contact Dermatitis 12, no. 2 (June 2001): 67–71. http://dx.doi.org/10.1097/01634989-200106000-00001.

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20

Matsushima, A., K. Shioya, M. Kobayashi, Y. Kodera, and Y. Inada. "Activation of Fibrinolysis with the Protease from Dermatophagoides Farinae." Thrombosis and Haemostasis 70, no. 03 (1993): 545. http://dx.doi.org/10.1055/s-0038-1649622.

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21

Matsuoka, Akito, Toshihide Isobe, Tsunehiro Aki, Seiji Kawamoto, Takaharu Hayashi, Yoshiko Asaoku, and Kazuhisa Ono. "A novel group 2 mite allergen from dermatophagoides farinae." World Allergy Organization Journal &NA; (November 2007): S256. http://dx.doi.org/10.1097/01.wox.0000301388.95686.93.

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22

Tang, Mingjuan, Ye Shen, Yuanlei Hu, Lei Cao, Ting Ni, Hongyu Zhang, and Zhongping Lin. "Allergenicity assay of allergen fromDermatophagoides farinae in transgenic tobacco." Chinese Science Bulletin 49, no. 5 (March 2004): 452–55. http://dx.doi.org/10.1007/bf02900963.

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23

Jamora, M. "Patch testing with 20% Dermatophagoides pteronyssinus/farinae (Chemotechnique) antigen." American Journal of Contact Dermatitis 12, no. 2 (June 2001): 67–71. http://dx.doi.org/10.1053/ajcd.2001.24161.

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Erban, Tomas, and Jan Hubert. "Two-dimensional gel proteomic analysis of Dermatophagoides farinae feces." Experimental and Applied Acarology 65, no. 1 (August 7, 2014): 73–87. http://dx.doi.org/10.1007/s10493-014-9848-1.

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TONGU, Yasumasa, Akira ISHII, and Heinan OH. "Ultrastructure of house-dust mites, Dermatophagoides farinae and D. pteronyssinus." Medical Entomology and Zoology 37, no. 3 (1986): 237–44. http://dx.doi.org/10.7601/mez.37.237.

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Bogomolov, A. Ye. "DIFFERENT METHODS OF DERMATOPHAGOIDES FARINAE SENSITIZATION DETERMINATION IN PATIENTS WITH RESPIRATORY ALLERGY." Asthma and allergy, no. 2 (2019): 24–28. http://dx.doi.org/10.31655/2307-3373-2019-2-24-28.

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Sharikadze, Olena. "PARTICULAR QUALITIES OF THE TREATMENT IN PRE-SCHOOL AGE CHILDREN SENSITIZED TO HOUSE DUST MITES ALLERGEN." Inter Collegas 4, no. 2 (July 22, 2017): 72–78. http://dx.doi.org/10.35339/ic.4.2.72-78.

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Sharikadze O.V.Background. This study determined the efficacy of sublingual allergen–specific immunotherapy (SLIT) in Ukrainian children younger than 5 years of age with allergic rhinitis and bronchial asthma sensitized to house dust mite allergens. Methods. A cohort prospective study was conducted over a two years period with assessment of the sensitization towards inhalant allergens, measured in-vivo by wheal size and number of positive reactions on the standard skin prick test (SPT). SPSS was used to analyse any statistical correlation. Results. A total of 125 atopic asthma or/and allergic rhinitis with the mean age of 4.11 ±0.83 who were sensitized to house dust mites Dermatophagoides pteronyssinus and/or Dermatophagoides farina were included. 47 children received two-years SLIT to treat house dust mite allergies using standardized extract of sublingual allergens containing a mixture of house dust mites (Der. pteronyssinus and Der. farinae) in the correlation of 1(0,175 НЕР):1(0,175 НЕР) (Diater, Spain). These patients were mono-sensitized with Der. pteronyssinus and Der. farinae or were SPT poly-sensitized, but these patients only had house dust mite allergy symptoms. In this group the assessment of clinical efficacy of SLIT showed the significant differences in VAS before treatment and 6 months after its receiving. The symptom “nasal obstruction” was assessed as 2.3±-1.6 points at the beginning of the therapy, and the data reduced almost twice (1.3±-1.1); Р <0,05 after 6 months of SLIT; then (12 and 24 months) it decreased to 0.91±0.9 and 0.34±0.5; Р <0,01, correspondingly. Conclusion. This study has shown that using of SLIT in atopic asthma or/and allergic rhinitis children under 5 year sensitized to house dust mites is an effective and safe treatment method and allows to quickly (over the first 6 months of SLIT) control the symptoms. The data of comparative analysis in the group of patients who didn’t receive SLIT has pointed to high frequency of disease symptom occurrence after the end of baseline therapy.KeyWords: sublingual allergen-specific immunotherapy, children, bronchial asthma, allergic rhinitis, sensitization, allergens, Diater ОСОБЛИВОСТІ ЛІКУВАННЯ ДІТЕЙ ДОШКІЛЬНОГО ВІКУ, СЕНСІБІЛІЗОВАНИХ ДО АЛЕРГЕНІВ ДОМАШНЬОГО ПИЛУШарикадзе О.В.Це дослідження визначило ефективність сублингвально алерген-специфічної імунотерапії (SLIT) українських дітей молодше 5 років з алергічним ринітом та бронхіальною астмою, сенсибілізованих до алергенів пилових кліщів. Методи. Проспективне дослідження когорти проводилося протягом двох років з оцінкою сенсибілізації до інгаляційних алергенів, виміряної in-vivo за розміром пухирів і кількості позитивних реакцій на стандартному тесті на шкірі (SPT). Для аналізу статистики використовувався пакет SPSS. Результати. Обстежено 125 дітей (середній вік 4,11 ± 0,83 років) з атопічною астмою та/або алергічним ринітом, які були сенсибілізовані до домашніх пилових кліщів Dermatophagoides pteronyssinus та/або Dermatophagoides farina. 47 дітей отримали дворічний курс SLIT з використанням стандартизованого екстракту сублінгвальних алергенів, що містять суміш кліщів домашнього пилу (Der. Pteronyssinus і Der. Farinae) в співвідношенні 1 (0,175 НЕР): 1 (0,175 НЕР) (Діатер, Іспанія). Пацієнти були моносенсібіровани Dermatophagoides pteronyssinus і / або Dermatophagoides farina або були полісенсібілізовані (за SPT), однак симптоми розвивалися тільки на домашній пил. У цій групі оцінка клінічної ефективності SLIT показала значні відмінності до лікування і через 6 місяців після його отримання. Симптом «носової обструкції» оцінювався як 2,3 ± 1,6 бала на початку терапії і зменшувалися майже в два рази (1,3 ± 1,1); Р <0,05 після 6 місяців SLIT. Потім (12 і 24 місяці) він знизився до 0,91 ± 0,9 і 0,34 ± 0,5; Р <0,01, відповідно. Висновок. Дослідження показало, що використання SLIT при атопічній астмі та/або алергічному риніті у дітей до 5 років, сенсибілізованих до домашніх пилових кліщів, є ефективним і безпечним методом лікування і дозволяє швидко (протягом перших 6 місяців SLIT) контролювати симптоми. Дані порівняльного аналізу в групі пацієнтів, які не отримували SLIT, вказують на високу частоту виникнення симптомів хвороби після закінчення базової терапії.Ключові слова: сублінгвальна алерген-специфічна імунотерапія, діти, бронхіальна астма, алергічний риніт, сенсибілізація, алергени, Діатер. ОСОБЕННОСТИ ЛЕЧЕНИЯ ДЕТЕЙ ДОШКОЛЬНОГО ВОЗРАСТА, СЕНСИБИЛИЗИРОВАННЫХ АЛЛЕРГЕНАМИ ДОМАШНЕЙ ПЫЛИШарикадзе Е.В.Это исследование определило эффективность сублингвальной аллерген-специфической иммунотерапии (SLIT) украинских детей моложе 5 лет с аллергическим ринитом и бронхиальной астмой, сенсибилизированных к аллергенам пылевых клещей. Методы. Проспективное исследование когорты проводилось в течение двух лет с оценкой сенсибилизации к ингаляционным аллергенам, измеренной in-vivo по размеру волдырей и количеству положительных реакций на стандартном тесте на коже (SPT). Для анализа статистики использовался пакет SPSS. Результаты. Обследованы 125 детей (средний возраст 4,11 ± 0,83 лет) с атопической астмой и/или аллергическим ринитом, которые были сенсибилизированы к домашним пылевым клещам Dermatophagoides pteronyssinus и/или Dermatophagoides farina. 47 детей получили двухлетний курс SLIT с использованием стандартизованного экстракта сублингвальных аллергенов, содержащих смесь клещей домашней пыли (Der. Pteronyssinus и Der. Farinae) в соотношении 1 (0,175 НЕР): 1 (0,175 НЕР) (Диатер, Испания). Пациенты были моносенсибированы Dermatophagoides pteronyssinus и/или Dermatophagoides farina или были полисенсибилизированы (по SPT), однако симптомы развивались только на домашнюю пыль. В этой группе оценка клинической эффективности SLIT показала значительные различия до лечения и через 6 месяцев после его получения. Симптом «носовой обструкции» оценивался как 2,3 ± -1,6 балла в начале терапии и уменьшались почти в два раза (1,3 ± -1,1); Р <0,05 после 6 месяцев SLIT. Затем (12 и 24 месяца) он снизился до 0,91 ± 0,9 и 0,34 ± 0,5; Р <0,01, соответственно. Вывод. Исследование показало, что использование SLIT при атопической астме или/или аллергическом рините детей до 5 лет, сенсибилизированных к домашним пылевым клещам, является эффективным и безопасным методом лечения и позволяет быстро (в течение первых 6 месяцев SLIT) контролировать симптомы. Данные сравнительного анализа в группе пациентов, которые не получали SLIT, указывают на высокую частоту появления симптомов болезни после окончания базовой терапии.Ключевые слова: сублингвальная аллерген-специфическая иммунотерапия, дети, бронхиальная астма, аллергический ринит, сенсибилизация, аллергены, Диатер.

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Ohashi, Yoshihiro, Hiroyuki Furuya, Yoshiaki Nakai, Yusuke Esaki, Hiroshi Ikeoka, and Shoko Kato. "Increased Ciliary Beating Frequency of Nasal Mucosa following Immunotherapy for Allergy." Annals of Otology, Rhinology & Laryngology 98, no. 5 (May 1989): 350–54. http://dx.doi.org/10.1177/000348948909800507.

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The present study was designed to elucidate the effect of immunotherapy on the beating frequency of nasal cilia in patients with nasal allergy. Of 40 patients with nasal allergy due to Dermatophagoides farinae, 20 were treated with immunotherapy by the use of D farinae extracts, and 20 control patients were treated with antihistamine tablets. Mucosal pieces were taken from the right inferior turbinate before and 1 year after the initiation of treatment, and the ciliary beating frequency (CBF) was examined by a photoelectric method. The use of antihistamine tablets did not increase CBF even when it relieved the nasal symptoms. Immunotherapy, on the other hand, increased CBF in 66.7% of patients when it alleviated their nasal symptoms. The CBF before immunotherapy of patients who showed an increased CBF after treatment was statistically higher than that of patients who did not.

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Chermprapai, Suttiwee, Pojnicha Chuayjuljit Anukkul, Teerawat Kritsadasima, Pudcharaporn Kromkhun, and Naris Thengchaisri. "Comparing the results of intradermal skin tests for four dust mite allergens in dogs with atopic dermatitis in Thailand." November-2020 13, no. 11 (2020): 2381–87. http://dx.doi.org/10.14202/vetworld.2020.2381-2387.

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Background and Aim: Hypersensitivity to house dust mites is a common cause of atopic dermatitis in dogs. The intradermal test (IDT) identifies allergens to be included in allergen-specific immunotherapy. Common mite allergens used for IDT include single source extracts obtained from Dermatophagoides farinae or Dermatophagoides pteronyssinus or multisource extracts from multimite species (mixed mites), as well as a combination of multimite species and proteins from feces and shed skin (house dust). The objectives of the present study were to evaluate the prevalence of mite sensitivity in dogs diagnosed with atopic dermatitis in different Thailand provinces and to determine if positive test results to mite allergens aligned. Materials and Methods: Eighty-two dogs (median age [range]: 5 years [11 months-11 years]; 51 males and 31 females) diagnosed with atopic dermatitis underwent IDTs with four different mite-related allergens (D. farinae, D. pteronyssinus, mixed mites, and house dust). The skin reactions were reported on a scale of 0-4 and the reactions 2+ were considered clinically relevant. The relationship between IDT results from different allergens was determined using Pearson's correlation coefficient (r). Fisher's exact test was used to compare IDT results for different mite allergens as well as for dogs residing in Bangkok versus other provinces in Thailand. Results: The prevalence (95% confidence interval [CI]) of positive IDT results for D. farinae, D. pteronyssinus, mixed mites, and house dust in dogs with atopic dermatitis was 64.63% (52.30-74.88), 58.54% (47.12-69.32), 47.56% (36.41-58.89), and 35.37% (25.12-46.70), respectively. A moderate correlation was found in IDT results between D. pteronyssinus and house dust (r=0.514), between D. pteronyssinus and D. farinae (r=0.426), and between D. farinae and mixed mites (r=0.423). The prevalence of dogs with positive IDT results for mite allergens with mono-sensitization, bi-sensitization, tri-sensitization, and quadru-sensitization did not differ significantly between dogs residing in Bangkok (11.63%, 18.60%, 25.58%, and 16.28%) and dogs residing in other provinces (12.82%, 30.77%, 35.90%, and 10.26%). The overall sensitivity (95% CI) and specificity (95% CI) of the mixed mites test associated with atopic dermatitis in dogs were 60.32% (47.20-72.40%) and 94.70% (74.00-99.90%), respectively. The overall sensitivity (95% CI) and specificity (95% CI) of the house dust test associated with atopic dermatitis in dogs were 42.90% (30.50-56.00%) and 89.50% (66.90-98.70%), respectively. Conclusion: House dust mites are an important source of allergens for dogs with atopic dermatitis. In the present study, no significant difference in the prevalence of atopic dermatitis was found in dogs living in the urban area compared with dogs living in the countryside. Application of multisource extracts from mites for IDT revealed a higher reaction to mixed mites than that of house dust.

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Hong, Chein Soo, Hae Sim Park, and Seung Heon Oh. "Dermatophagoides Farinae, an Important Allergenic Substance in Buckwheat-Husk Pillows." Yonsei Medical Journal 28, no. 4 (1987): 274. http://dx.doi.org/10.3349/ymj.1987.28.4.274.

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HUGHES, T. E. "The embryonie development of the mite Tyroglgphus farinae Linnaeus 1758." Proceedings of the Zoological Society of London 119, no. 4 (August 20, 2009): 873–86. http://dx.doi.org/10.1111/j.1096-3642.1950.tb00914.x.

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TANG, Mingjuan. "Allergenicity assay of allergen from Dermatophagoides farinae in transgenic tobacco." Chinese Science Bulletin 49, no. 5 (2004): 452. http://dx.doi.org/10.1360/03wc0455.

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Hirota, Ryoji, Hiroyuki Nakamura, Sabah Asif Bhatti, Nlandu Roger Ngatu, Basilua Andre Muzembo, Narongpon Dumavibhat, Masamitsu Eitoku, Masayoshi Sawamura, and Narufumi Suganuma. "Limonene inhalation reduces allergic airway inflammation inDermatophagoides farinae-treated mice." Inhalation Toxicology 24, no. 6 (May 2012): 373–81. http://dx.doi.org/10.3109/08958378.2012.675528.

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Siegert, Monica Krauze, Guilherme Liberato Da Silva, Maicon Toldi, Liana Johann, and Noeli Juarez Ferla. "Assessment on abiotic factors and the presence of storage mites in an animal feed factory." Systematic and Applied Acarology 23, no. 12 (December 7, 2018): 2317. http://dx.doi.org/10.11158/saa.23.12.4.

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Pest mites found in grain, flour, and feed warehouses and also on the shelves of business establishments are common in Brazil. This study aimed at describing the mite fauna associated with environmental factors and several production-line environments inside animal feed factories. Mites were collected from: package depositing (PD), rice bran milling machine (RB), corn conveyor belt (CB), soybean silo (SS), pigeon nests (PN), animal product elevator (AP), pellet cooler (PC), and from the roof of an animal feed factory (R). A total of 2401 mites were collected, belonging to 13 species in 12 families, along with Uropodina and the suborder Oribatida. Higher richness was observed for Cheyletidae, and the highest richness was observed in PN and SS. Dermatophagoides farinae was the most abundant species (883 specimens), followed by T. putrescentiae (654) and C. malaccensis (506). In PC, the place with the highest infestation, we observed 36% of total mite populations, followed by CB with 17.5%, and RB and SS, with 14% each. There was no significant correlation among mite infestation, temperature, and relative humidity (RH). The period with the highest abundance was between March and August. The most abundant species in March was D. farinae, and T. putrescentiae was the most abundant in August. From December to February, C. malaccensis was the most predominant species. Thus, this study showed the prevalence of two pest species (D. farinae and T. putrescentiae) in several production-line environments in an animal feed factory and the presence of a potential predator, C. malaccensis.

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Hongzhi, Gu, Deng Xiangfen, Zhang Jing, and Xiaoyan. "Analysis of skin prick test results for 224 patients with eczema." E3S Web of Conferences 185 (2020): 03004. http://dx.doi.org/10.1051/e3sconf/202018503004.

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Objective: To understand the common inhalant allergens and food allergens and their characteristics on patients with eczema in Chongqing area. Method: Skin prick tests of common inhalant allergens and food allergens were performed on 224 patients with eczema and the test results were analyzed. Results: Among the 224 patients with eczema, 137 reacted positively to one or more allergens, with a positive rate reaching 61.2%; the inhalant allergens that ranked top 3 in the positive rate were dermatophagoides pteronyssinus (41.1%), dermatophagoides farina (37.5%), cockroach (35.3%). The top three food allergens were shrimp (7.1%), milk (4.5%), egg (4%). Conclusions: Patients with eczema were allergic to one or more allergens, and the major inhalant allergens were dermatophagoides pteronyssinus, dermatophagoides farinae and cockroaches. The positive rate of food allergens was lower that the inhalant counterparts, and the difference between male and female was not statistically significant (P>0.05). Allergen prick tests could facilitate identifying the inhalant allergens and food allergens of patients with eczema, improve treatment and health education of patients with eczema, and provide a reliable basis for effective prevention and normalized treatment.

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TATAMI, Kenji, Naoki MORI, Ritsuo NISHIDA, and Yasumasa KUWAHARA. "2-Hydroxy-6-methylbenzaldehyde : the female sex pheromone of the house dust mite Dermatophagoides farinae (Astigmata : Pyroglyphidae)." Medical Entomology and Zoology 52, no. 4 (2001): 279–86. http://dx.doi.org/10.7601/mez.52.279.

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Choopong, Jintarat, Onrapak Reamtong, Nitat Sookrung, Watee Seesuay, Nitaya Indrawattana, Yuwaporn Sakolvaree, Wanpen Chaicumpa, and Anchalee Tungtrongchitr. "Proteome, Allergenome, and Novel Allergens of House Dust Mite, Dermatophagoides farinae." Journal of Proteome Research 15, no. 2 (January 25, 2016): 422–30. http://dx.doi.org/10.1021/acs.jproteome.5b00663.

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OROURKE, M., S. JIN, and A. ATMOWIDJOJO. "171 Peak expiratory flow (PEF) variability and exposure to Dermatophagoides farinae." Journal of Allergy and Clinical Immunology 97, no. 1 (January 1996): 225. http://dx.doi.org/10.1016/s0091-6749(96)80389-7.

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LEMAO, J., C. MAYER, G. PELTRE, F. DESVAUX, B. DAVID, A. WEYER, and H. SENECHAL. "Mapping of Dermatophagoides farinae mite allergens by two-dimensional immunoblotting☆☆☆★." Journal of Allergy and Clinical Immunology 102, no. 4 (October 1998): 631–36. http://dx.doi.org/10.1016/s0091-6749(98)70280-5.

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Arlian, Larry G., Jacqueline S. Neal, and DiAnn L. Vyszenski-Moher. "Reducing relative humidity to control the house dust mite Dermatophagoides farinae." Journal of Allergy and Clinical Immunology 104, no. 4 (October 1999): 852–56. http://dx.doi.org/10.1016/s0091-6749(99)70298-8.

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Kitajima, Takaaki, Masashi Muroi, Naomi Yamashita, and Ken-ichi Tanamoto. "Toll-Like Receptors Required for Dermatophagoides farinae to Activate NF-κB." Biological and Pharmaceutical Bulletin 37, no. 1 (2014): 74–80. http://dx.doi.org/10.1248/bpb.b13-00595.

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Maruo, K., and T. Ono. "111 Proteolytic activity of a group 3 allergen of Dermatophagoides farinae." Journal of Dermatological Science 15, no. 2 (August 1997): 121. http://dx.doi.org/10.1016/s0923-1811(97)81813-0.

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Matsushima, A., K. Shioya, M. Kobayashi, Y. Kodera, and Y. Inada. "Activation of Blood Coagulation Syetem with the Protease from Dermatophagoides Farinae." Thrombosis and Haemostasis 69, no. 05 (1993): 531–32. http://dx.doi.org/10.1055/s-0038-1651653.

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Zhang, Han-zhong, Wei Xie, Ying Wang, Jian Chen, and Ting-huan Wen. "Dermatophagoides farinae allergen encapsule for oral immunotherapy with HDM allergic rhinitis." Systematic and Applied Acarology 23, no. 9 (August 31, 2018): 1782. http://dx.doi.org/10.11158/saa.23.9.5.

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It is well known that the house dust mites (HDMs) are the most common and potent inhalant allergens world-wide and the allergen immunotherapy (AIT) can efficaciously and safely ameliorate the allergic symptoms. Different formulations and routes of HDMs AIT have been achieved symptomatic improvement with mite allergic rhinitis (AR) and/or asthma. The object of the present article is to observe the efficacy and safety of oral immunotherapy (OIT) by enteric-coated capsules (EC) of Dermatophagoides farinae allergen (Df) with mite AR. A year of single blind placebo trial was applied. A total of 54 AR patients aged 25.8 in average with/without asthma and skin prick test (SPT) positive in HDMs were selected into either active or placebo groups. The OIT started with 5 days of dose rush induction, succeeded by a maintenance dose for 12 months. The efficacy of the treatment was assessed by symptomatic evaluation and laboratory in vivo and in vitro parameters of pre-immunotherapy (pre-IT) and post-immunotherapy (post-IT) statistically. The patients each received a total accumulative dose of 16 715BU Df protein nitrogen, and 87.5% (21/24) subjects achieved symptomatic improvement. The post-IT symptom scores decreased (t=11.07, P<0.001); visual analog scale (VAS) decreased (t=10.68, P<0.001); number of patients required symptom-medication decreased from 23/24 to 3/24 cases (c2=33.57, P<0.001); SPT wheal sizes of both Df and Dp significantly reduced (Df t=2.64, P=0.015 and Dp t=6.01, P<0.001); nasal provocation test (NPT) with the antigen tolerance elevated more than 3 times (c2=9.65, P=0.008). The only unchanged parameter was the tIgE levels (P=0.07). The parameters of placebo group were changed but not significant statistically or negligible. There were no local or general adverse reactions in both groups happened in the one year course of OIT. It is concluded that the newly designed formulation and route of clinical administration by Df EC OIT with AR were comparable to that of Df sublingual IT. The new formulation is more convenient and promising approach to treat AR.

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SHIBASAKI, M., S. ISOYAMA, R. SUMAZAKI, and H. TAKITA. "Crossreactivity of IgE antibody against Dermatophagoides farinae with Limulus polyphemus agglutinin." Clinical Experimental Allergy 24, no. 4 (April 1994): 386–93. http://dx.doi.org/10.1111/j.1365-2222.1994.tb00252.x.

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FUJII, S., K. ONO, S. SHIGETA, T. JYO, and U. YAMASHITA. "Human T cell responses to recombinant mite antigens of Dermatophagoides farinae." Clinical & Experimental Immunology 108, no. 2 (May 1997): 284–88. http://dx.doi.org/10.1046/j.1365-2249.1997.3431244.x.

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Santos, Brenda. "Transmission ofEscherichia coliby the American dust mite,Dermatophagoides farinae(Acari: Pyroglyphidae)." International Journal of Acarology 26, no. 3 (September 2000): 243–45. http://dx.doi.org/10.1080/01647950008684195.

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Yasueda, Hiroshi, Haruhisa Mita, Yasuo Yui, and Takao Shida. "Isolation and Characterization of Two Allergens from Dermatophagoides farinae." International Archives of Allergy and Immunology 81, no. 3 (1986): 214–23. http://dx.doi.org/10.1159/000234137.

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Lee, Jinyoung, Ju Yeong Kim, Myung-hee Yi, Younjee Hwang, In-Yong Lee, Sung-Hyun Nam, Dongeun Yong, and Tai-Soon Yong. "Comparative microbiome analysis of Dermatophagoides farinae, Dermatophagoides pteronyssinus, and Tyrophagus putrescentiae." Journal of Allergy and Clinical Immunology 143, no. 4 (April 2019): 1620–23. http://dx.doi.org/10.1016/j.jaci.2018.10.062.

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Weyer, A., P. Ougen, J. P. Dandeu, F. Marchand, and B. David. "Passivein vitro sensitization of human basophils with dermatophagoides farinae specific IgE." Agents and Actions 18, no. 1-2 (April 1986): 178–81. http://dx.doi.org/10.1007/bf01988015.

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Journal articles on the topic 'Farinae'

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