Relevant bibliographies by topics / Fast Disintegration Tablet (FDT)

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Academic literature on the topic 'Fast Disintegration Tablet (FDT)'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Fast Disintegration Tablet (FDT)"

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RAHMAWATI, TIAS EKA. "Effect of Disintegrating Agents on Red Ginger (Zingiber officinale Roxb) Dry Extract Fast Disintegrating Tablets Using Direct Compression Method." Media Farmasi Indonesia 19, no. 2 (2024): 130–36. http://dx.doi.org/10.53359/mfi.v19i2.278.

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Red ginger (Zingiber officinale Roxb) is one of the medicinal plants that is effective as a medicine for nausea and vomiting. One of the techniques for developing traditional medicinal products is to make fast disintegrating tablets (FDT). This research aims to compare the effect of these various disintegrating materials on the physical properties of FDT. FDT red ginger extract is made using the direct compression method. The tablets obtained were physically evaluated including weight uniformity, hardness, friability, and disintegration time. The statistical results using the one-way ANOVA tes
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2

Fahmansyah, Lingga Pratama, Agus S, and Suparman. "REVIEW : OF SUPERDISINTEGRANT INGREDIENTS IN FAST DISINTEGRANT TABLET TABLET PREPARATIONS." Medical Sains : Jurnal Ilmiah Kefarmasian 9, no. 3 (2024): 857–76. http://dx.doi.org/10.37874/ms.v9i3.1292.

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This study aimed to evaluate the potential of synthetic and natural disintegrating agents in fast-disintegrating tablet (FDT) formulations. The methodology used includes a comprehensive literature review on the definition, characteristics, working mechanisms, and applications of super disintegrants in the manufacture of FDTs. The results of the study showed that super disintegrants play an important role in facilitating rapid disintegration of tablets. Synthetic super disintegrants such as crospovidone, croscarmellose sodium, and sodium starch glycolate have the advantage of lower concentratio
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Zulfikar, Muhaini, Arisanty Arisanty, and Sisilia Tresia Rosmala Dewi. "Formulasi Fast Disintegrating Tablet Ekstrak Rimpang Kunyit (Curcuma domestica) dan Perasan Umbi Kentang (Solanum tuberosum L)." Journal of Experimental and Clinical Pharmacy (JECP) 3, no. 2 (2023): 88. http://dx.doi.org/10.52365/jecp.v3i2.483.

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Fast Disintegrating Tablet (FDT) merupakan tablet yang dapat dipecah dalam waktu kurang dari 60 detik saat diletakkan di atas lidah dengan jumlah air yang minimal. Kunyit dan kentang digunakan untuk menurunkan kadar asam dalam lambung yang bertujuan untuk mengobati pasien penderita gastritis. Tujuan penelitian ini membuat formulasi FDT rimpang kunyit (Curcuma domestica) dan perasan umbi kentang (Solanum tuberosum L) dengan variasi konsentrasi sodium starch glycolate sebagai bahan penghancur yaitu formula I (2%), formula II (3%) dan formula III (4%). Penelitian dilakukan dengan metode observasi
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4

Shrestha, Sumit, and Sujata Bhandari. "Formulation Optimization and in-vitro Evaluation of Diclofenac Fast Disintegrating Tablets." MedS Alliance Journal of Medicine and Medical Sciences 3, no. 5 (2023): 30–34. http://dx.doi.org/10.3126/mjmms.v3i5.60041.

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INTRODUCTION: Fast disintegrating tablets (FDTs) are solid dosage forms that disintegrate and dissolve in the mouth without the need for water within a matter of seconds. In the present study, a fast-disintegrating tablet of diclofenac sodium was prepared using WOWTAB (without water) technology, and its in-vitro characters were analyzed to prepare an optimum formulation. MATERIALS AND METHODS: Diclofenac sodium and its reference standard along with other excipients were collected. Softer tablets with hardness ranging from 1.493 to 1.522 kg/cm2 were prepared using Plackett-Burman (PB) design an
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5

Rahane, RD, and Punit R. Rachh. "A REVIEW ON FAST DISSOLVING TABLET." Journal of Drug Delivery and Therapeutics 8, no. 5 (2018): 50–55. http://dx.doi.org/10.22270/jddt.v8i5.1888.

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The convenience of administration and improved patient compliance are important in the design of oral drug delivery system which remains the preferred route of drug delivery inspite of various disadvantages. Fast disintegrating tablets (FDTs) have received ever-increasing demand during the last decade, and the field has become a rapidly growing area in the pharmaceutical industry. The popularity and usefulness of the formulation resulted in development of several FDT technologies. These techniques render the disintegration of tablet rapidly and dissolve in mouth in five seconds without chewing
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Chauhan, Kalindi, Rakesh Solanki, and Shivani Sharma. "A REVIEW ON FAST DISSOLVING TABLET." International Journal of Applied Pharmaceutics 10, no. 6 (2018): 1. http://dx.doi.org/10.22159/ijap.2018v10i6.28134.

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In the present scientific scenario, the drug delivery technology has become extremely competitive and quickly evolving with ever-increasing demand. Fast dissolving tablet (FDT) is one such style of an innovative and distinctive drug delivery system. Once FDT is placed on the tongue, it disintegrates or dissolves quickly (in seconds) without chewing or water. Fast dissolving pills became well-liked because of higher patient compliance and most popular over typical capsules and tablets. Numerous FDT products entered the market in the nineteen eighties. This novel drug delivery like FDT or mouth
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7

Sendy Fitriani and Monica Kristiani. "PENGARUH VARIASI KONSENTRASI CROSCARMELLOSE SODIUM SEBAGAI SUPERDISINTEGRANT TERHADAP KARAKTERISTIK FISIK FAST DISSOLVING TABLET (FDT) GLIBENKLAMID." Journal Clinical Pharmacy and Pharmaceutical Science 1, no. 1 (2022): 26–32. http://dx.doi.org/10.61740/jcp2s.v1i1.4.

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Glibenclamide is a second generation DM drug sulfonylurea group with the properties of lowering blood sugar levels. Most glibenklamid preparations are available in conventional tablet form and can be developed into pharmaceutical preparations that are more practical and accelerate the therapeutic effect of Fast Dissolving Tablet (FDT). The physical characteristics of the FDT are faster wetting and disintegration times compared to conventional tablets. Superdisintegrant is an important component in FDT preparations because it affects the time of wettability and disintegration time of FDT. The p
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8

Rahmawati, Tias Eka, Agus Siswanto, and Asmiyenti Djaliasrin Djalil. "Optimization of Fast Disintegrating Tablets Diphenhydramine HCl using Co-process of Cross-link Yellow Kepok Banana Starch, Crospovidone, and Microcrystalline Cellulose." JURNAL ILMU KEFARMASIAN INDONESIA 21, no. 2 (2023): 231. http://dx.doi.org/10.35814/jifi.v21i2.1406.

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Diphenhydramine HCl is an antihistamine drug that is available in conventional tablet form. This study aimed to produce the optimum formula for a diphenhydramine fast disintegrating tablet (FDT) using a modification of starch, crospovidone, and microcrystalline cellulose (MCC) to produce quality tablets that meet the tablet's physical requirements and tablet dissolution. Starch modification was made using a two-step method of starch cross-link, then continued with silica coprecipitation. FDT was prepared by the direct compression method. Optimisation with the simplex lattice design (SLD) model
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9

Jayaramu, Rajamma Abburu, Sateesha Shivally Boregowda, Addanki Rahul Deva Varma, and Chandan Kalegowda. "Development of fast dispersing tablets of nebivolol: experimental and computational approaches to study formulation characteristics." Brazilian Journal of Pharmaceutical Sciences 50, no. 4 (2014): 956–63. http://dx.doi.org/10.1590/s1984-82502014000400031.

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Formulation of FDT (fast dispersing tablets) of nebivolol was optimized and evaluated using simplex lattice design (SLD). The influence of type and concentration of three disintegrants viz.,Ac-Di-Sol, Primojel and Polyplasdone XL on hardness, friability and disintegration time of tablet was studied. Response surface plot and the polynomial equations were used to evaluate influence of polymer on the tablet properties. Results were statistically analyzed using ANOVA, and a p < 0.05 was considered statistically significant. Results reveal that fibrous integrity and optimal degree of substituti
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10

Putranti, Widyasari, Desty Restia Rahmawati, Nining Sugihartini, and Teuku Nanda Saifullah. "Influence of croscarmellose in fast disintegrating tablet of Syzygium polyanthum extract." International Journal of Public Health Science (IJPHS) 13, no. 1 (2024): 438. http://dx.doi.org/10.11591/ijphs.v13i1.22666.

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Bay leaves (<em>Syzygium polyanthum</em>) contain the flavonoid quercetin which can be used as an antihyperlipidemic drug. The development of antihyperlipidemic drug formula in the form of fast disintegrating tablet (FDT) is needed for patients who experience dysphagia. FDT preparations require an optimal super disintegrant concentration to produce a good drug formula. This study aims to develop the FDT formula of bay leaves extract using the super disintegrant croscarmellose sodium (CCS) intra and extra-granular. FDT formulation using the wet granulation method with variations of
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Book chapters on the topic "Fast Disintegration Tablet (FDT)"

1

Sukanya, M., V. Rupa Sree Devi, K. Ravi Shankar, G. Ramana Reddy, and R. Anusha. "Optimization of Telmisartan Fast Dissolving Tablets by 32 Factorial Design." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00533.

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Telmisartan belongs to BCS Class II drug and needs enhancement in dissolution rate. The main objective of the study is to produce rapid dissolving tablets of telmisartan by complexation with β-cyclodextrin(βCD) and by using solid dispersions of MCC, Starch 1500, PEG 4000, Primojel and Mannitol. Telmisartan tablets with fast dissolution characteristics employing βCD were prepared using 32 factorial design and were prepared by direct compression method. Dissolution of Telmisartan from the βCD complexes was rapid and higher when compared to Telmisartan pure drug and with different carriers. Hence
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Devi, V. Rupa Sree, M. Sukanya, K. Ravi Shankar, G. Ramana Reddy, and KNV Chenchu Lakshmi. "Formulation, Preparation, and Evaluation of Nebivolol Fast-Dissolving Tablets by Using 32 Factorial Design." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00510.

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Nebivolol comes under BCS Class II Classification, so there is a need to improve the dissolution rate. The motive of the current work is to formulate the fast-dissolving tablets of Nebivolol from optimised solid dispersion by allowing complexation using solid dispersions of PEG 4000, Starch 1500, Poloxamer 188, and β-cyclodextrin (β CD). Nebivolol tablets with fast dissolution characteristics employing βCD were prepared using a 32 factorial study employing by direct compression technique. Dissolution of Nebivolol from the β-CD complexes was rapid and higher when seen with that of Pure Nebivolo
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