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Journal articles on the topic 'Fast Dissolving Sublingual Film'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Sangale, Vaishali D., Smita S. Aher, and Ravindra B. Saudagar. "Fast Dissolving Sublingual Film." Asian Journal of Research in Pharmaceutical Science 6, no. 3 (2016): 153. http://dx.doi.org/10.5958/2231-5659.2016.00021.7.

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2

Fathei, Marzieh, Mitra Alami-milani, Sara Salatin, et al. "Fast Dissolving Sublingual Strips: A Novel Approach for the Delivery of Isosorbide Dinitrate." Pharmaceutical Sciences 25, no. 4 (2019): 311–18. http://dx.doi.org/10.15171/ps.2019.34.

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Background: Isosorbide dinitrate (ISDN) is used for treating the angina attacks. In addition, oral ISDN is available in immediate and sustained release formulations and the bioavailability of ISDN is about 20-25% when taken orally. Further, the ISDN films are developed for sublingual drug delivery by improving drug bioavailability. The present study aimed to design and evaluate the physicochemical properties of the film formulation for sublingual delivery of ISDN. Methods: In the present study, sublingual films were prepared by the solvent casting technique using the hydroxypropyl methylcellul

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3

Kareem, Hawraa, and Nawal Rajab. "Formulation and Characterization of Eplerenone Nanocrystal as Sublingual Fast-dissolving Film." Iraqi Journal of Pharmaceutical Sciences 33, no. 4 (2024): 150–64. https://doi.org/10.31351/vol33iss4pp150-164.

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Eplerenone, a Class-II according to the biopharmaceutical classification system (BCS), with poor water solubility, resulting in low bioavailability. To address these limitations, this study aimed to improve the drug solubility and dissolution rate, by formulating it as nanocrystals (NCs). The NCs were intended to enhance Eplerenone's solubility, thereby increasing its bioavailability when taken orally. Additionally, load it as a sublingual fast-dissolving film to be released immediately and enhance effectiveness by avoiding first-pass metabolism. Using the solvent anti-solvent precipitation me

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4

Kareem, Hawraa, and Nawal Rajab. "Formulation and Characterization of Eplerenone Nanocrystal as Sublingual Fast-dissolving Film." Iraqi Journal of Pharmaceutical Sciences 33, no. 4 (2024): 151–65. https://doi.org/10.31351/vol33iss4pp151-165.

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Eplerenone, a Class-II according to the biopharmaceutical classification system (BCS), with poor water solubility, resulting in low bioavailability. To address these limitations, this study aimed to improve the drug solubility and dissolution rate, by formulating it as nanocrystals (NCs). The NCs were intended to enhance Eplerenone's solubility, thereby increasing its bioavailability when taken orally. Additionally, load it as a sublingual fast-dissolving film to be released immediately and enhance effectiveness by avoiding first-pass metabolism. Using the solvent anti-solvent precipitation me

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5

Bamnia, Sooraj, Sunita Sonartiya, and Ekta Yadav. "A REVIEW ON FAST DISSOLVING FILM." International Journal of Pharmaceutical Sciences and Medicine 9, no. 5 (2024): 50–61. http://dx.doi.org/10.47760/ijpsm.2024.v09i05.006.

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Orally fast dissolving films (OFDFs) have been introduced in the market recently as they provide convenience and ease of use over other dosage forms such as orally disintegrating tablets. This technology evolved over the past few years from the confection and oral care markets in the form of breath strips and became a novel and widely accepted form by consumers, so OFDFs are gaining the interest of large number of pharmaceutical industries. Orally fast dissolving film is the type of drug delivery system which when placed in the oral cavity, disintegrate or dissolve within few seconds without t

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6

RATHORE, LAKSHITA, NARENDRA GEHALOT, and VIKAS JAIN. "A SHORT REVIEW ON ADVANCEMENT IN FAST DISSOLVING ORAL THIN FILMS." Current Research in Pharmaceutical Sciences 11, no. 4 (2022): 112–17. http://dx.doi.org/10.24092/crps.2021.110404.

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The pharmaceutical industry is pursuing the development of thin films as a novel method of drug administration. Thin films as an alternative to standard dosage forms have been described. They are a very adaptable platform capable of producing immediate, local, or systemic effects. Additionally, these systems are self-administered, which is advantageous for patients with dysphagia, elderly, pediatric, or bedridden patients and those who cannot administer with water. Thin film drug delivery methods are available for oral, buccal, sublingual, ophthalmic, and transdermal administration. This revie

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7

Tooba, Arif Rana, Qasim Maria, Kalam Alfia, and Parveen Saba. "Administration of Fast Dissolving Oral Thin Film Orlistat drug via sublingual route instead of oral route." International Journal of Innovative Science and Research Technology 7, no. 5 (2022): 1691–706. https://doi.org/10.5281/zenodo.6825008.

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Patients with obesity are given orlistat (120) mg capsules three times a day by oral route of administration, although oral method of administration does not produce good and accurate outcomes. Aim: To see if giving orlistat in tablet form as a sublingual medication delivery mechanism is useful in treating obesity in patients. Densign and Setting: This article is based on past research and does not include any experiments involving humans or animals undertaken by any of the authors. Method: We use Google Scholar, Medline, PubMed, Research Gate, and Science Direct to retrieve scientific databas

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8

Julie, E. James Sojan Abraham Joshua Bineesha K. B. Jicky T. Panicker Shaiju S. Dharan. "Formulation, Evaluation and Comparative Study of Effects of Super Disintegrants in Sublingual Fast Dissolving Niosomal Films of Nifedipine." British Journal of BioMedical Research 03, no. 04 (2019): 947–64. https://doi.org/10.24942/bjbmr.2019.526.

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The aim of the present work was to prepare and evaluate sublingual fast dissolving niosomal films containing Nifedipine with the purpose to achieve quick onset of action. Niosomes are utilized for prolonged release of the drug, and its film increases bioavailability via the sublingual route. Niosomes were prepared using span 60 and cholesterol at different drug to surfactant ratios. The niosomes were characterized for particle size and zeta-potential. The selected niosomal formulation was incorporated into polymeric films using hydroxypropyl methyl cellulose E15 and methyl cellulose as film-fo

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9

Alhamhoom, Yahya, Ashitha Kakarlapudi Said, Avichal Kumar, et al. "Sublingual Fast-Dissolving Thin Films of Loratadine: Characterization, In Vitro and Ex Vivo Evaluation." Polymers 16, no. 20 (2024): 2919. http://dx.doi.org/10.3390/polym16202919.

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Loratadine (LOR) is a second-generation antihistamine that exhibits a low and variable oral bioavailability (10–40%) and delayed onset owing to poor solubility and an extensive first-pass effect. Therefore, in light of the clinical need, the main goal of the present study was to develop sublingual fast-dissolving thin films of LOR–citric acid co-amorphous systems (LOR-CAs) with the aim of eliciting a faster onset and improving the bioavailability. We formulated sublingual fast-dissolving thin films of LOR by a film-casting technique using hydrophilic polymers like hydroxypropyl methylcellulose

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10

Perumalla, Ashok Kumar* Dr.Deenanath Jhade. "A PRECISE REVIEW ON FAST DISSOLVING ORAL FILMS." Indo American Journal of Pharmaceutical Sciences 04, no. 09 (2017): 3193–201. https://doi.org/10.5281/zenodo.936361.

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Orally fast dissolving films (OFDFs) have been introduced in the market recently as they provide convenience and ease of use over other dosage forms such as orally disintegrating tablets. This technology evolved over the past few years from the confection and oral care markets in the form of breath strips and became a novel and widely accepted form by consumers, so OFDFs are gaining the interest of large number of pharmaceutical industries. Orally fast dissolving film is the type of drug delivery system which when placed in the oral cavity, disintegrate or dissolve within few seconds without t

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11

Singh, Swati, Rajat Pawar, and Sunita Patidar. "A REVIEW ON MOUTH DISSOLVING FILM- A NOVEL APPROACH." International Journal of Pharmaceutical Sciences and Medicine 9, no. 2 (2024): 36–51. http://dx.doi.org/10.47760/ijpsm.2024.v09i02.006.

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The oral route is one of the most important routes for local and systemic drug delivery due to its large surface area, high permeability and blood flow. Mouth dissolving films are the most advanced oral forms as they are simpler and easier to use than other dosage forms such as Oro-soluble tablets, sublingual tablets. Fast dissolving drug delivery system were rapidly developed in the 1970s as an alternative to capsules, syrups, and tablets for adults and adolescents who have difficulty swallowing conventional oral solid dosage form. The Oro- soluble film dissolves and disintegrates in less tha

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12

Akter, Sayeda Mushfika, Sreebash Chandra Bhowmik, Marzia Alam, Saimon Shahriar, Tanoy Saha, and Md Saiful Islam Pathan. "Formulation and Estimation of Rapidly Dissolving Sublingual Thin Film of Vildagliptin." Bangladesh Pharmaceutical Journal 26, no. 2 (2023): 212–18. http://dx.doi.org/10.3329/bpj.v26i2.67811.

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The purpose of the present research was to develop a fast and rapidly dissolving polymeric sublingual thin film of vildagliptin due to its simplicity of use as an alternative to oral disintegrating tablets and better compliance for diabetic patients. Nine different formulations (F1-F9) of vildagliptin sublingual films were produced using diverse concentrations of polymer A and plasticizer B by solvent casting method. Several physicochemical properties, including morphological properties, weight variation test, film thickness, folding endurance, surface pH, percentage of moisture loss, in-vitro

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13

Palepu, Swathi. "Preparation and evaluation of fast dissolving sublingual film of lisinopril." Journal of Drug Delivery and Therapeutics 9, no. 1-s (2019): 101–6. http://dx.doi.org/10.22270/jddt.v9i1-s.2342.

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14

Avni P, Desai. "An Overview of Oral Thin Film Drug Delivery Systems with Fast Dissolving Films." International Journal of Pharmaceutical Sciences and Medicine 8, no. 8 (2023): 1–10. http://dx.doi.org/10.47760/ijpsm.2023.v08i08.001.

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Fast-dissolving oral thin films (OTFs), rather than tablets, are the product of choice for many pharmaceutical businesses. The benefits of tablets (precise dose, simple administration) and liquid dosage forms (easily swallowed, quick bioavailability) are all present in films. Four out of five patients, according to statistics, prefer orally disintegrating dose forms over traditional solid oral dosage forms. Children, the elderly, people who are bedridden, people who are emetic, and those who have CNS illnesses have trouble swallowing or digesting solid dose forms. Many of these individuals ref

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15

Uddin, Mohammad Nasir, Amanda Allon, Monzurul A. Roni, and Samir Kouzi. "Overview and Future Potential of Fast Dissolving Buccal Films as Drug Delivery System for Vaccines." Journal of Pharmacy & Pharmaceutical Sciences 22 (August 5, 2019): 388–406. http://dx.doi.org/10.18433/jpps30528.

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Vaccination is considered one of the most successful public health interventions of the modern era. Vaccines are categorized based on the antigen used, delivery system and the route of administration. Traditional vaccines are produced from the dead, attenuated or inactivated pathogens that cause disease. However, newly developed vaccines are DNA based, liposome based, and virus like particle (VLP) based which are more effective and specific to some malignant diseases. The delivery system of vaccines has been advanced along with time as well. New delivery systems such as nanoparticles, liposome

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16

Rajagopalan, Senthamarai, Dinesh Rajendhiran, Ismail Abdulrahim Mohamed, and Shakila Banu Sherbudeen. "Fast dissolving oral thin films: an innovative herbal drug delivery system." International Journal of Research in Medical Sciences 12, no. 8 (2024): 3085–90. http://dx.doi.org/10.18203/2320-6012.ijrms20242250.

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Fast-dissolving drug delivery systems were first developed as an alternative to common dosage forms in the late 1970s. The oral thin film is an innovative drug administration approach based on transdermal patch technology. These systems consist of solid dosage forms that dissolve and disintegrate quickly in the mouth without the need for water. Oral thin films (OTFs) and oral disintegrating tablets (ODTs) are two types of fast-acting pharmaceutical delivery methods. ODTs are "A solid dosage form containing medicinal substances, which disintegrates rapidly, usually within a matter of seconds, w

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17

BEYATRICKS, JESINDHA, and ,. Dhananjaya. "Development of Fast Dissolving Oral Films Containing Vitamin B6 for Nausea and Vomiting of Pregnancy (NVP)." Journal of Drug Delivery and Therapeutics 9, no. 3 (2019): 51–59. http://dx.doi.org/10.22270/jddt.v9i3.2735.

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The aim of this study was to formulate and evaluate the oral fast-dissolving film of Vitamin B6 for the effective management of motion sickness and vomiting during pregnancy. Fast-dissolving films were prepared by the solvent-casting method using different polymers, HPMC-15 and Pullulan, along with Propylene glycol as a plasticizer. The Fourier-transform infrared study for the drug-polymer interaction was carried out. Evaluation of physical parameters such as physical appearance, surface texture, uniformity of weight, uniformity of strip thickness, surface pH, folding endurance, uniformity of

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18

R, Karthik D., H. S. Keerthy, and Rajkumar Prasad Yadav. "A Review on Fast Dissolving Oral Films." Asian Journal of Pharmaceutical Research and Development 9, no. 3 (2021): 122–28. http://dx.doi.org/10.22270/ajprd.v9i3.969.

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Oral route are the most convenient and common route of administration of drug because of the low cost of therapy and ease of administration lead to high levels of patient compliance as in the form of tablets and capsules. Generally In some cases, the oral solid dosage form may become difficult especially in swallowing. So to overcome these problems, fast dissolving drug delivery systems have been developed which disintegrate or dissolve within one minute when placed in the mouth without water or chewing. These are the formulations administered without water. These thin sized oral film stripes

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19

Alsafar, Zahraa A., and Fatima J. Jawad. "Formulation and characterization of lercanidipine hcl nanoparticles as fast-dissolving sublingual film." ACTA Pharmaceutica Sciencia 63, no. 1 (2025): 44. https://doi.org/10.23893/1307-2080.aps6303.

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20

Bir, Pawan Kumar* and Sandeep Kumar. "FAST DISSOLVING FILMS: AN INNOVATIVE APPROACH TO ORAL DRUG DELIVERY." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 05 (2018): 3714–19. https://doi.org/10.5281/zenodo.1245921.

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<em>Fast dissolving films is a novel approach that are rapidly gaining interest for the patients having difficulties in swallowing or chewing of solid dosage forms such as tablets or capsules. Fast-dissolving drug-delivery systems were first developed in the late 1970s for pediatric and geriatric patients who experience difficulties in swallowing traditional oral solid dosage forms. These films may deliver the drug in a systemically manner through sublingual or buccal route and also used for local action. The present review reflects the information regarding the ideal characteristics, method o

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Демчук, М. Б., Ю. Я. Мельник, Н. В. Маланчук, Т. А. Грошовий, and В. Й. Скорохода. "Research the influence of excipients on the technological properties of captopril fast dissolving films." Farmatsevtychnyi zhurnal, no. 2 (April 25, 2022): 61–72. http://dx.doi.org/10.32352/0367-3057.2.22.06.

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Drug-loaded films are of great interest among fast-dissolving drug-delivery systems. The creation of fast-dissolving films for the treatment of cardiovascular diseases is important.The first inhibitor of angiotensin-converting enzyme to appear on the world market was captopril, which is used to treat hypertension, chronic heart failure and others. Captopril has an antihypertensive effect, which manifests itself within 5–15 minutes after sublingual administration. The aim of our study was to develop the technology of captopril fast dissolving films by solvent casting method and analyze th

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22

Shivani, Honmode* Prakash katakam Jadhav S. B. "Comprehensive Review on Fast Mouth Dissolving Film As Novel Drug Delivery System." International Journal in Pharmaceutical Sciences 2, no. 1 (2024): 124–41. https://doi.org/10.5281/zenodo.10477153.

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Fast mouth dissolving films are solid dosage types that, when placed in the mouth, dissolve or disintegrate over the course of a few seconds. They are not manufactured or palatable. Fast-dissolving films are becoming more popular as an alternative to quick-dissolving tablets in order to reduce patients' concerns about choking and to overcome patients' obstacles. A complex alternative to the traditional pills, capsules, and liquids often associated with prescription and over-the-counter drugs is the quickly disintegrating thin film. Thin film strips are often intended for oral administration, w

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Kelodiya, Jayesh, Sunil Kumar Shah, C. K. Tyagi, and Prabhakar Budholiya. "FORMULATION, DEVELOPMENT OF FAST DISSOLVING SUBLINGUAL WAFERS OF AN ANTIEMETIC DRUG USING FILM FORMER." Asian Journal of Pharmaceutical Education and Research 10, no. 4 (2021): 71. http://dx.doi.org/10.38164/ajper/10.4.2021.71-78.

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24

V, Attal, and Daniel K. "Preparation of Mouth Dissolving Sublingual Film of Fixed Dose Combination of Hydrochlorothiazide and Losartan Potassium and Statistical Optimization of Film." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 03 (2024): 1344–52. http://dx.doi.org/10.25258/ijddt.14.3.13.

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Fast-dissolving films (FDFs) are innovative dosage forms offering advantages such as improved patient compliance, rapid onset of action, precise dosing, and favorable taste. Particularly beneficial for patients unable to swallow or require immediate drug absorption, FDFs dissolve rapidly in the mouth, releasing medication directly into the oral cavity. The sublingual application enhances drug delivery due to the high permeability of the sublingual mucosa, bypassing hepatic first-pass metabolism. This route is advantageous for drugs like losartan potassium (LP) and hydrochlorothiazide (HCZ), wh

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25

Teaima, Mahmoud, Mohamed Yasser, Nehal Elfar, Kamel Shoueir, Mohamed El-Nabarawi, and Doaa Helal. "Construction of sublingual trilaminated Eszopiclone fast dissolving film for the treatment of Insomnia: Formulation, characterization and In vivo clinical comparative pharmacokinetic study in healthy human subjects." PLOS ONE 17, no. 6 (2022): e0266019. http://dx.doi.org/10.1371/journal.pone.0266019.

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Background Disturbed sleep can cause to m health problems such as cognitive impairment, depressed mood, and negative effects on cardiovascular, endocrine, and immune function. This study formulates and optimizes Eszopiclone trilaminate fast dissolving film. Methods Prepared Eszopiclone trilaminate fast dissolving film (Eszopiclone TFDF) was characterized by disintegration time, drug release, tensile strength (TS), percentage elongation (EB%), folding endurance, taste masking test, and in vitro dissolution test. The selected formulas were F2 (0.5% xanthan gum, 10% propylene glycol), F4 (3% sodi

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S., Jyothi Sri* Dr. K. S. Murali Krishna D. Kusuma Ch. Uma Shankar. "FORMULATION AND IN-VITRO EVALUATION OF BENAZEPRIL MOUTH DISSOLVING FILMS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 01 (2018): 552–60. https://doi.org/10.5281/zenodo.1162756.

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Oral route is most preferred route by medical practitioners and manufacturer due to highest acceptability of patients. But oral drug delivery systems still need some advancement to be made because of their some drawbacks related to particular class of patients which includes geriatric, pediatric and dysphasic patients associated with many medical conditions as they have difficulty in swallowing or chewing solid dosage forms. The aim of this is to highlight the potential role of fast dissolving drug delivery in achieving effective drug delivery of antihypertensive drug. It gives rapid absorptio

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Tejas Popat Desai, Tejas Popat Desai, Rohan Pramod Dhumal, Avdhoot Dilip Khot Avdhoot Dilip Khot, et al. "Exploring the Potential of Fast Dissolving oral Film for the Dental Pain Management." International Journal of Pharmaceutical Research and Applications 10, no. 3 (2025): 2108–22. https://doi.org/10.35629/4494-100321082122.

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In order to improve clinical outcomes, dentists frequently prescribe analgesics since pain management is an essential component of dental practice. In the late 1970s, fast-dissolving medication delivery systems were created as an alternative to tablets, capsules, and syrups for elderly and paediatric patients who had trouble swallowing conventional oral solid dosage forms. They are a multifaceted platform that can offer systemic, local, or immediate solutions. FDF have become a newer method of oral medication administration since they are easier to use and more convenient than previous dosage

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Shalini, G. C., Preeti Karwa, Aisha Khanum, and Vinay Pandit. "A Laconic Overview on Fast Dissolving Sublingual Films as Propitious Dosage Form." Drug Delivery Letters 4, no. 1 (2014): 49–61. http://dx.doi.org/10.2174/22103031113039990010.

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29

Singh, Anoop, Shradha Shende, and Navjot Singh. "FORMULATION, DEVELOPMENT AND EVALUATION OF FAST DISSOLVING SUBLINGUAL WAFERS OF AN ANTIPSYCHOTIC DRUG USING FILM FORMER." Asian Journal of Pharmaceutical Education and Research 10, no. 4 (2021): 18. http://dx.doi.org/10.38164/ajper/10.4.2021.18-26.

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30

Song, Qing, Chengying Shen, Baode Shen, et al. "Development of a fast dissolving sublingual film containing meloxicam nanocrystals for enhanced dissolution and earlier absorption." Journal of Drug Delivery Science and Technology 43 (February 2018): 243–52. http://dx.doi.org/10.1016/j.jddst.2017.10.020.

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Pandey, Prachi, and Sonam Chauhan. "Fast Dissolving Sublingual Films of Zolmitriptan : A Novel treatment approach for Migraine Attacks." Indian Journal of Pharmaceutical Education and Research 48, supplementary (2014): 67–72. http://dx.doi.org/10.5530/ijper.48.4s.9.

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32

Tayel, Saadya A., Mohamed A. El Nabarawi, Maha M. Amin, and Mohamed H. Abou Ghaly. "Sumatriptan succinate sublingual fast dissolving thin films: formulation and in vitro/in vivo evaluation." Pharmaceutical Development and Technology 21, no. 3 (2015): 328–37. http://dx.doi.org/10.3109/10837450.2014.1003655.

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Fetih, Gihan, and Ayat Allam. "Sublingual fast dissolving niosomal films for enhanced bioavailability and prolonged effect of metoprolol tartrate." Drug Design, Development and Therapy Volume 10 (August 2016): 2421–33. http://dx.doi.org/10.2147/dddt.s113775.

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Sayed, Soha, Howida Kamal Ibrahim, Magdy Ibrahim Mohamed, and Mohamed Farid El-Milligi. "Fast-Dissolving Sublingual Films of Terbutaline Sulfate: Formulation and In Vitro/In Vivo Evaluation." Molecular Pharmaceutics 10, no. 8 (2013): 2942–47. http://dx.doi.org/10.1021/mp4000713.

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Londhe, Vaishali, and Rucha Shirsat. "Formulation and Characterization of Fast-Dissolving Sublingual Film of Iloperidone Using Box–Behnken Design for Enhancement of Oral Bioavailability." AAPS PharmSciTech 19, no. 3 (2018): 1392–400. http://dx.doi.org/10.1208/s12249-018-0954-y.

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Husseini, Rabab A., Mahran Mohamed Abd El-Emam, Sherif E. Emam, Eslam Hamed, Abdelsamed I. Elshamy, and Dina M. Abdelnabi. "Rutin-loaded fast-dissolving sublingual niosomal film: Design, characterization, hepatoprotective potential, and pharmacokinetic evaluation in ceftriaxone-induced liver injury in rats." Journal of Drug Delivery Science and Technology 112 (October 2025): 107225. https://doi.org/10.1016/j.jddst.2025.107225.

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Shah, Jigar N., Kashyap N. Shah та Tejal A. Mehta. "Hydroxy propyl β-cyclodextrin complexation of promethazine hydrochloride for the formulation of fast dissolving sublingual film: in vitro and in vivo evaluation". Journal of Pharmaceutical Investigation 45, № 1 (2014): 91–99. http://dx.doi.org/10.1007/s40005-014-0150-3.

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Alshaya, Hassa A., Ahmed J. Alfahad, Fatemah M. Alsulaihem, et al. "Fast-Dissolving Nifedipine and Atorvastatin Calcium Electrospun Nanofibers as a Potential Buccal Delivery System." Pharmaceutics 14, no. 2 (2022): 358. http://dx.doi.org/10.3390/pharmaceutics14020358.

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Geriatric patients are more likely to suffer from multiple chronic diseases that require using several drugs, which are commonly ingested. However, to enhance geriatric patients’ convenience, the electrospun nanofiber system was previously proven to be a successful alternative for the existing oral dosage forms, i.e., tablets and capsules. These nanofibers prepared either as single- or multi-layered fibers could hold at least one active compound in each layer. They might also be fabricated as ultra-disintegrated fibrous films for oral cavity administration, i.e., buccal or sublingual, to impro

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Koland, M., V. P. Sandeep, and N. R. Charyulu. "Fast Dissolving Sublingual Films of Ondansetron Hydrochloride: Effect of Additives on in vitro Drug Release and Mucosal Permeation." Journal of Young Pharmacists 2, no. 3 (2010): 216–22. http://dx.doi.org/10.4103/0975-1483.66790.

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40

Singh, Harmanpreet, Yash Paul Singla, Ramandeep Singh Narang, Deepti Pandita, Simerjit Singh, and Jasjeet Kaur Narang. "Frovatriptan loaded hydroxy propyl methyl cellulose/treated chitosan based composite fast dissolving sublingual films for management of migraine." Journal of Drug Delivery Science and Technology 47 (October 2018): 230–39. http://dx.doi.org/10.1016/j.jddst.2018.06.018.

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41

Maghsoodi, Maryam, Mahdieh Rahmani, Hamed Ghavimi, et al. "Fast Dissolving Sublingual Films Containing Sumatriptan Alone and Combined with Methoclopramide: Evaluation in Vitro Drug Release and Mucosal Permeation." Pharmaceutical Sciences 22, no. 3 (2016): 153–63. http://dx.doi.org/10.15171/ps.2016.25.

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S, Morris, Badola A, Nainwal N, Ghalwan PK, and Soni P. "Oral Transmucosal Drug Delivery: A Potential Route To Treat Migraine." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 04 (2024): 978–83. https://doi.org/10.25258/ijddt.14.4.73.

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Migraine is a complex neurological disease. Migraine headaches described as vascular headaches cause a throbbing and pulsating pain around the head. A migraine attack involves stimulating the sympathetic nerve system, and increased sympathetic activity leads to nausea, vomiting, and diarrhea. Therefore, treatment of migraine requires immediate onset of action of the drug to give fast relief from the pain. Absorption of drugs directly through the oral cavity is one of the efficient ways of treating various diseases. The oral cavity has low enzymatic activity, ease of access for patients to rece

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Patil, P. B., D. A. Patil, L. R. Zawar, B. Patil, and G. B. Patil. "DEVELOPMENT AND CHARACTERIZATION OF SUBLINGUAL FILM CONTAINING ROPINIROLE HYDROCHLORIDE." INDIAN DRUGS 56, no. 07 (2019): 33–42. http://dx.doi.org/10.53879/id.56.07.11513.

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In the present work films of ropinirole hydrochloride were prepared by using polymers such as hydroxy propyl methyl cellulose (HPMC E-15) and polyethylene glycol (PEG-400) as plasticizers, by a solvent casting method, for treatment of Parkinson's disease. HPMC E-15 was used as film forming agent in the range of concentration 50 mg – 600 mg and PEG-400 was used as plasticizer in the range of concentration 0.3-1.0 ml for solvent casting method. the optimized concentration of film forming agent was 400 mg and plasticizer concentration was 0.7ml. By using optimized concentration, Ropinirole Hydroc

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Şenel, Sevda, and Tansel Comoglu. "Orally disintegrating tablets, fast-dissolving, buccal and sublingual formulations." Pharmaceutical Development and Technology 23, no. 5 (2018): 431. http://dx.doi.org/10.1080/10837450.2018.1462471.

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Sakshi, D. Patil* Shubhangi S. Ambekar Sandip A. Tadavi Sunil P. Pawar. "Review On Mouth Dissolving Film: The Advancement In Oral Drug Delivery." International Journal in Pharmaceutical Sciences 2, no. 3 (2024): 559–68. https://doi.org/10.5281/zenodo.10824195.

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Mouth dissolving films are the kind of drug delivery system which is gaining interest from a wide range of pharmaceutical industries. This is due to there  convenience and it’s easy to use than other dosage forms like buccal tablets and sublingual tablets. By studying transdermal patch technology, mouth dissolving film was formulated. Thin, solid dosage forms called mouth dissolving films dissolves in the mouth within seconds to a minute without chewing or water intake. Because of the oral buccal mucosa's high vascularization, medications can be absorbed immediately and reach the bl

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Patil, Pallavi C., S. K. Shrivastava, Vaidehi S., and Ashwini P. "ORAL FAST DISSOLVING DRUG DELIVERY SYSTEM: A MODERN APPROACH FOR PATIENT COMPLIANCE." International Journal of Drug Regulatory Affairs 2, no. 2 (2018): 49–60. http://dx.doi.org/10.22270/ijdra.v2i2.131.

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This review represents importance of mouth dissolving films as compared to other oral dosage forms. Fast dissolving oral drug delivery system are solid dosage form which disintegrate or dissolve within seconds when placed in the mouth without need of water or chewing. First developed fast dissolving dosage form in formulation and the rapid disintegrating properties were obtained through a special procedure or formulation modification, hence mouth dissolving film is proved to be better alternative in such cases. This fast dissolving drug delivery system is suited for the drugs which undergo hig

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Carpenter, Garima, and R. K. Maheshwari. "Formulation and development of fast dissolving oral film of a poorly soluble drug, frusemide with improved drug loading using mixed solvency concept and its evaluation." Journal of Drug Delivery and Therapeutics 8, no. 6 (2018): 132–41. http://dx.doi.org/10.22270/jddt.v8i6.2034.

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The aim of the present research work is to explore the application of mixed solvency concept to formulate and develop a fast dissolving oral film of furosemide with improved drug loading. In the present study, poorly soluble drug, furosemide was tried to be solubilized by employing the combination of physiologically compatible water-soluble additives (solubilizers) to formulate its fast dissolving formulations. For the development of fast dissolving oral film, firstly, different film forming polymers were tested for their film properties. The second fast dissolving layer was also formed and op

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Kaur, Prabhjot, and Rajeev Garg. "Oral dissolving film: present and future aspects." Journal of Drug Delivery and Therapeutics 8, no. 6 (2018): 373–77. http://dx.doi.org/10.22270/jddt.v8i6.2050.

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Over the past few decades, tendency toward innovative drug delivery systems has almightily increased attempts to ensure efficacy, safety and patient acceptability. As discovery and development of new chemical agents is a complex, expensive and time consuming process, so recent trends are shifting toward designing and developing innovative drug delivery systems for existing drugs. Orally fast dissolving film is the kind of drug delivery system which when placed in the oral cavity, disintegrate or dissolve within a few seconds without the intake of water. Oral fast dissolving film is relatively

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Bhalse, Pinki, Apurva Pagare, and Rajat Pawar. "A REVIEW ON MOUTH DISSOLVING FILM." International Journal of Pharmaceutical Sciences and Medicine 9, no. 1 (2024): 82–93. http://dx.doi.org/10.47760/ijpsm.2024.v09i01.007.

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Oral route is considered as one of the most convenient route for administration of various pharmaceutical dosage forms like, tablet, capsule, syrup, suspension and emulsion. Fast Dissolving Drug Delivery systems have developed various fast disintegrating preparations like mouth dissolving film, MDT. Oral thin film are new dosage form that are prepared from hydrophilic polymer which are when placed in mouth, buccal cavity disintegrate rapidly. Mouth dissolving film is superior as compare to mouth dissolving tablet as the cost of production is low. Geriatric and pediatric patients are facing dif

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Kheawfu, Kantaporn, Adchareeya Kaewpinta, Wisinee Chanmahasathien, Pornchai Rachtanapun, and Pensak Jantrawut. "Extraction of Nicotine from Tobacco Leaves and Development of Fast Dissolving Nicotine Extract Film." Membranes 11, no. 6 (2021): 403. http://dx.doi.org/10.3390/membranes11060403.

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Nicotine (NCT), administered in the form of a fast dissolving oral delivery system, can be a potential alternative to nicotine replacement therapy. NCT was extracted by maceration and acid-base extraction methods from Burley tobacco leaves with different stalk positions and extraction yield and NCT content were further determined. The extract with the highest nicotine content was selected for incorporation into a fast dissolving film formulation. The optimized film was evaluated for its physical and mechanical properties, in vitro disintegration, and drug release profile. The results demonstra

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