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Journal articles on the topic 'Fast Dissolving Tablet'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Aniket, G. Karodade, P. Wable Aniket, kharbal Gopal, S. Bhagat Sunil, and P. Deshmukh Swati. "Fast dissolving tablet." GSC Biological and Pharmaceutical Sciences 27, no. 1 (2024): 001–7. https://doi.org/10.5281/zenodo.11951879.

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Fast dissolving tablets have emerged as a popular dosage form, particularly beneficial for pediatric and geriatric patients facing challenges such as dysphagia or hand tremors. These tablets dissolve quickly in saliva without needing water, enhancing compliance and effectiveness of therapy. They offer advantages like easy portability, accurate dosing, and improved bioavailability. Various technologies, including spray drying and melt granulation, have been developed for their manufacturing. This review provides comprehensive information on fast dissolving tablets, covering their definition, ad

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2

Aniket G. Karodade, Aniket P. Wable, Gopal kharbal, Sunil S. Bhagat, and Swati P. Deshmukh. "Fast dissolving tablet." GSC Biological and Pharmaceutical Sciences 27, no. 1 (2024): 001–7. http://dx.doi.org/10.30574/gscbps.2024.27.1.0096.

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Fast dissolving tablets have emerged as a popular dosage form, particularly beneficial for pediatric and geriatric patients facing challenges such as dysphagia or hand tremors. These tablets dissolve quickly in saliva without needing water, enhancing compliance and effectiveness of therapy. They offer advantages like easy portability, accurate dosing, and improved bioavailability. Various technologies, including spray drying and melt granulation, have been developed for their manufacturing. This review provides comprehensive information on fast dissolving tablets, covering their definition, ad

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3

Masih, Ashish, and Ajay Kumar Tiwari. "FORMULATION AND EVALUATION OF FAST DISSOLVING TABLETS OF AMOXYCILLIN TRIHYDRATE AND POTASSIUM CLAVULANATE." International Journal of Current Pharmaceutical Research 9, no. 2 (2017): 48. http://dx.doi.org/10.22159/ijcpr.2017v9i2.17385.

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Objective: The present work is aimed to formulate fast dissolving stable tablet formulation a preferred combination of Amoxycillin trihydrate (Beta-lactum antibiotic) and Potassium clavulanate (Beta-lactum inhibitor) by using various super disintegrants.Methods: Fast dissolving tablets are prepared by direct compression method using super disintegrants i.e. sodium starch glycolate, crospovidone, croscarmellose sodium. Aspartame as a sweetener and trusil mango flavor were used to increase palatability. Reduction in the dose of Amoxycillin trihydrate and Potassium clavulanate tablet was possible

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4

Rushikesh, Bhanage* Dhanashri Ghude Dr. Anil Pawar. "Fast Dissolving Tablet: An Overview." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 5190–97. https://doi.org/10.5281/zenodo.15563036.

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Oral delivery is the preferred route of drug delivery in the pharmaceutical industry because to its safety, convenience, and cost-effectiveness, with high patient compliance. Fast dissolving tablets have become a prevalent and widely recognized dose form, particularly for young patients due to the insufficient development of their muscular and neural systems, as well as for senior individuals experiencing Parkinson’s disease or hand tremors. Nowadays, a small number of solid dosage forms, such as tablets and capsules, have issues such dysphagia, which makes it difficult to swallow. This

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5

S., Aher Smita, Saudagar R. B., and Shinde Mayuri S. "REVIEW: FAST DISSOLVING TABLET." International Journal of Current Pharmaceutical Research 10, no. 2 (2018): 5. http://dx.doi.org/10.22159/ijcpr.2018v10i2.25876.

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Fast dissolving tablets is one of the most widely accepted dosage forms and also most popular dosage form, especially for pediatric patients because of incomplete development of the muscular and nervous system and a case of geriatric patients suffering from Parkinson’s disorder or hand tremors. Some solid dosage forms like tablets and capsules are present days facing the problems like difficulty in swallowing (dysphagia), resulting in many incidences of non-compliance and making the therapy ineffective. Oral dosage form and oral route are the most preferred route of administration for various

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6

Kaur, Kiranpreet* and Garg Rajeev. "FAST DISSOLVING TABLET – AN INNOVATIVE APPROACH." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 10 (2018): 10603–11. https://doi.org/10.5281/zenodo.1469989.

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<em>Fast dissolving tablets are the most supportive and widely accepted dosage forms, commonly for pediatric patients. </em><em>Some solid dosage forms like capsules and tablets have issue like worry of swallowing called dysphagia, resulting in matter of patient non-compliance and making the therapy inefficient. FDT disintegrate or dissolve quickly in the saliva in lack of water in within a few seconds (less than 60 seconds) and are real fast dissolving tablets. FDTs are designed to disintegrate speedily, absorb faster so,in vitro drug release time improve and this property of drugs enhanced b

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7

Prachi, Pawar* Akanksha Jadhav Gayatri Ghodke Vidya Anap Dr. Sanjay Ingale. "Review On Fast Dissolving Tablets." International Journal of Pharmaceutical Sciences 2, no. 10 (2024): 1748–60. https://doi.org/10.5281/zenodo.14011672.

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The fast dissolving tablet (FDT) is a new and unique drug delivery system that is rapidly focusing major  attention in the reasearch field of fast dissolving technology. In recent times, a few solid dosage forms, such as tablets and capsules, are dealing with issues such dysphagia, which causes difficulties  swallowing and leads to a high rate of non-compliance, ultimately causing the therapy  ineffective.Fast dissolving tablet are disintegrating or/and dissolve quickly without the need of water. These tablets are designed to dissolve or break down in saliva in the mouth, u

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8

Rahane, RD, and Punit R. Rachh. "A REVIEW ON FAST DISSOLVING TABLET." Journal of Drug Delivery and Therapeutics 8, no. 5 (2018): 50–55. http://dx.doi.org/10.22270/jddt.v8i5.1888.

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The convenience of administration and improved patient compliance are important in the design of oral drug delivery system which remains the preferred route of drug delivery inspite of various disadvantages. Fast disintegrating tablets (FDTs) have received ever-increasing demand during the last decade, and the field has become a rapidly growing area in the pharmaceutical industry. The popularity and usefulness of the formulation resulted in development of several FDT technologies. These techniques render the disintegration of tablet rapidly and dissolve in mouth in five seconds without chewing

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9

A V, Misal, G. R. Godage, and S. A. Belge. "Current Progress in the Formulation and Taste-Masking Technologies for Mouth Dissolving Tablets." International Journal of Pharmaceutical Sciences and Nanotechnology 9, no. 5 (2016): 3452–57. http://dx.doi.org/10.37285/ijpsn.2016.9.5.2.

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Within the past one decade, mouth dissolving or fast disintegrating tablet technology has received ever-increasing demand. Mouth dissolving or fast disintegrating tablet can be defined as a solid dosage form that can disintegrate or dissolved within half-minute in the oral cavity resulting in a solution or suspension without administration of water. Mouth dissolving tablet have been formulated for pediatric, geriatric, bedridden patient or mentally ill patient and may not have access to water. Patient incompliance occurs due to bitterness of formulation. So masking the bitterness become in dis

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10

Dev, Asish, Shravan Kumar Yadav, S. K. Kar, Smitapadma Mohanty, and Om Shelke. "Formulation and Characterization of Aceclofenac Mouth Dissolving Tablet by QbD." Journal of Drug Delivery and Therapeutics 9, no. 5 (2019): 43–50. http://dx.doi.org/10.22270/jddt.v9i5.3538.

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The purpose of this study was to develop fast dissolving tablets of Aceclofenac using different concentration of super disintegrants. Fast dissolving tablets of Aceclofenac were prepared by dry granulation technique using croscarmellose sodium together with avicel ph as superdisintegrants. The porous granules were then compressed in to tablets by direct compression technique. These tablets were evaluated for drug content, weight variation, friability, hardness, wetting time and dispersion time. All the formulations showed low weight variation with dispersion time less than 90 seconds and rapid

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11

Ahmed, Mohd Salman, Nikita Upadhyay, and P. K. Dubey. "A REVIEW ON FAST DISSOLVING TABLET." International Journal of Pharmaceutical Sciences and Medicine 7, no. 5 (2022): 37–47. http://dx.doi.org/10.47760/ijpsm.2022.v07i05.004.

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Fast dissolving tablets (FDTs) emerged as one of the popular and widely accepted dosage forms. Few solid dosage forms like capsules and tablets are present days facing the problems like difficulty in swallowing (dysphagia) resulting many incidences of non-compliance and making the therapy ineffective. Specifically for paediatric patients because of incomplete development of the muscular and nervous system and case of geriatric patients suffering from Parkinson’s disorder. Oral dosage form and oral route are the most preferred administration route for various drugs with limitations like first-p

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12

Shah, Akashkumar, and Khushbu Patel. "Development and Evaluation of Therapeutically Beneficial Fast Dissolving Tablet Containing Herbal Extracts: A Quality by Design Approach." Indian Journal Of Science And Technology 18, no. 9 (2025): 682–95. https://doi.org/10.17485/ijst/v18i9.3480.

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Objectives: The QbD approach validates the formulation during development, ensuring therapeutic benefits through the careful selection of herbal extracts. Methods: Oral dosage forms, especially fast dissolving tablets with different herbal extracts (curcumin, saffron, and gingerol) were developed to get their desired therapeutic actions immediately. Quality by Design (QbD) emphasizes a science-based approach to product development. Design of Experiments (DOE) and ANOVA are used to analyze high-risk Critical Quality Attributes (CQAs). Design Expert software helps determine the optimal quantitie

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13

Masih, Ashish, Amar Kumar, Shivam Singh, and Ajay Kumar Tiwari. "FAST DISSOLVING TABLETS: A REVIEW." International Journal of Current Pharmaceutical Research 9, no. 2 (2017): 8. http://dx.doi.org/10.22159/ijcpr.2017v9i2.17382.

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Fast dissolving tablets emerge as one of the popular and widely accepted dosage forms, especially for pediatric patients because of incomplete development of the muscular and nervous system and a case of geriatric patients suffering from Parkinson’s disorder or hand tremors. Few solid dosage forms like capsules and tablets are present days facing the problems like difficulty in swallowing (dysphagia), resulting in many incidences of non-compliance and making the therapy ineffective. Oral dosage form and oral route are the most preferred route of administration for various drugs have limitation

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14

Sharma, Ankit, Avinash Kumar Gupta, Manish Kumar Gupta, and Vijay Sharma. "A Review: Formulation and Characterization of Fast Dissolving Tablet of Carvidilol." Journal of Drug Delivery and Therapeutics 9, no. 3 (2019): 749–52. http://dx.doi.org/10.22270/jddt.v9i3.2738.

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Carvedilol a poorly water soluble drug undergoes extensive first pass metabolism, which reduces its bioavailability to 25-30%. Fast dissolving tablets of Carvedilol were prepared with the purpose of delivering the drug directly into the systemic circulation and bypassing the hepatic first pass metabolism with a concomitant increase in bioavailability. The solubility of Carvedilol was improved by forming inclusion complex with cyclodextrin which was then further used for the formulation of Fast dissolving tablet. Keywords: Carvedilol, Superdisintegrats, Fast dissolving Tablets and FDTs.

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15

Chauhan, Kalindi, Rakesh Solanki, and Shivani Sharma. "A REVIEW ON FAST DISSOLVING TABLET." International Journal of Applied Pharmaceutics 10, no. 6 (2018): 1. http://dx.doi.org/10.22159/ijap.2018v10i6.28134.

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In the present scientific scenario, the drug delivery technology has become extremely competitive and quickly evolving with ever-increasing demand. Fast dissolving tablet (FDT) is one such style of an innovative and distinctive drug delivery system. Once FDT is placed on the tongue, it disintegrates or dissolves quickly (in seconds) without chewing or water. Fast dissolving pills became well-liked because of higher patient compliance and most popular over typical capsules and tablets. Numerous FDT products entered the market in the nineteen eighties. This novel drug delivery like FDT or mouth

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16

Ashutosh, Sharma, Bansal Mayank, and Sweta. "A Review on Fast Dissolving Tablet." International Journal of Current Pharmaceutical Review and Research 15, no. 04 (2023): 215–19. https://doi.org/10.5281/zenodo.12635965.

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AbstractThe convenience of administration and improved patient compliance are important in thedesign of oral drug delivery system which remains the preferred route of drug delivery inspiteof various disadvantages. Fast disintegrating tablets (FDTs) have received ever- increasingdemand during the last decade, and the field has become a rapidly growing area in thepharmaceutical industry. The popularity and usefulness of the formulation resulted indevelopment of several FDT technologies. These techniques render the disintegration oftablet rapidly and dissolve in mouth in five seconds without chew

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17

Patil, Shailesh B., and Jitendra D. More. "Expansion and Valuation of Naproxen Sodium Fast Dissolving Tablet." Journal of Pharmaceutical Research 23, no. 3 (2024): 178–88. http://dx.doi.org/10.18579/jopcr/v23.3.98.

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The evaluation of Naproxen Sodium Fast Dissolving Tablets emphasizes the critical role of careful formulation design and thorough testing in pharmaceutical development. Among the formulations, F7 demonstrated outstanding properties, including excellent flow characteristics and optimal tablet hardness. Stability testing over a four-week period showed consistent performance, though minor variations in tablet attributes were observed. Continuous monitoring is advised to ensure sustained efficacy. The in-vitro release profile revealed rapid disintegration and dissolution, crucial for prompt drug r

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18

Afreen, Nagori* Akanksha Jagwani Vikas Jain. "A Review Of Fast Dissolving Tablet." International Journal in Pharmaceutical Sciences 2, no. 5 (2024): 601–9. https://doi.org/10.5281/zenodo.11186249.

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The fast-dissolving tablet (FDT) is an innovative and unique drug delivery system that is rapidly gaining attention in fast-dissolving technology research. Fast dissolving tablets are proving to be one of the most popular and widely accepted dosage forms, especially in pediatric patients due to incomplete development of muscles and nervous system and in geriatric patients suffering from Parkinson's disease or hand tremors. The oral dosage form and route is the most preferred route of administration for various drugs that have limitations such as e.g. First-pass metabolism, psychiatric patients

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19

Momin, Md Mubashshir, and Asish Dev. "Fast dissolving tablets: a novel approach." Indian Journal of Pharmaceutical and Biological Research 3, no. 01 (2015): 18–23. http://dx.doi.org/10.30750/ijpbr.3.1.4.

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An oral route of drug administration is the most popular route of administration. It have wide acceptance up to 50-60% of total dosage forms. Tablet is the most popular dosage forms existing today because of its convenience of self administration, compactness and easy manufacturing; however hand tremors, dysphasia in case of geriatric patients, the underdeveloped muscular and nervous systems in young individuals and case of uncooperative patients, the problem of swallowing is common phenomenon which leads to poor patient compliance. Mouth dissolving tablets (FDT) or fast dissolving tablets; (F

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20

Sumit S. Mohite, Amarnath B. Munde, Jai A. Lagad, and Trupti Shaha. "A Review on Mouth Dissolving Tablets." International Journal of Scientific Research in Science and Technology 11, no. 2 (2024): 427–35. http://dx.doi.org/10.32628/ijsrst52411276.

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Traditional dosage forms, such as pills and capsules, are now used to treat conditions like dysphagia, which increases the risk of non-compliance and makes therapy ineffective. Mouth dissolving tablets were created to solve the problems associated with traditional dosage forms. They offer good hardness, dose uniformity, and convenience of administration. For pediatric, geriatric, and travel patients, they are the preferred dose form. Providing the MDTs with enough hardness, integrity, and disintegration speed without the requirement for water was the aim of their development. For fast-dissolvi

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21

Abdul Qadir, Bhavana Singh, Deepika Joshi, and Nidhi Semwal. "Fast dissolving tablet: An updated review." World Journal of Biology Pharmacy and Health Sciences 11, no. 3 (2022): 052–59. http://dx.doi.org/10.30574/wjbphs.2022.11.3.0135.

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Improved patient management and patient tracking are essential to the development of an oral drug delivery system that remains a popular drug delivery route despite various maladies. Fast-dispersing pills (FDTs) have found growing demand over the past decade, and the field has become a fast-growing area in the pharmaceutical industry. The popularity and usefulness of the construction has led to the development of many FDT technologies. These are ways to make the tablet dissolve faster and spill in the mouth for five seconds without chewing and the need for beneficial water especially for child

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22

Abdul, Qadir, Singh Bhavana, Joshi Deepika, and Semwal Nidhi. "Fast dissolving tablet: An updated review." World Journal of Biology Pharmacy and Health Sciences 11, no. 3 (2022): 052–59. https://doi.org/10.5281/zenodo.7181372.

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Improved patient management and patient tracking are essential to the development of an oral drug delivery system that remains a popular drug delivery route despite various maladies. Fast-dispersing pills (FDTs) have found growing demand over the past decade, and the field has become a fast-growing area in the pharmaceutical industry. The popularity and usefulness of the construction has led to the development of many FDT technologies. These are ways to make the tablet dissolve faster and spill in the mouth for five seconds without chewing and the need for beneficial water especially for child

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23

S.Spandana*, T.Mallika Bhavani M.L.Prasanna. "ISOLATION, CHARACTERIZATION AND INVESTIGATION OF STARCH MALEATE AS NOVEL SUPERDISINTEGRANT IN DEVELOPING OF TELMISARTAN FAST DISSOLVING TABLETS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 08 (2018): 7611–23. https://doi.org/10.5281/zenodo.1400676.

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<em>Telmisartan, an angiotension II receptor antagonist widely used in the treatment of hypertension, characterized by low aqueous solubility. The present study focus on the formulation and evaluation of Telmisartan fast dissolving a tablet which offers a solution for those patients having difficulty in swallowing. In the formulation of fast dissolving tablets of Telmisartan, superdisintegrants like Starch Maleate (Novel Superdisintegrant), crosscarmellose sodium and crospovidone are employed. The synthesized Starch Maleate was characterized by FTIR, X-ray etc. The Telmisartan - Starch Maleate

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24

Akashkumar, Shah, and Patel Khushbu. "Development and Evaluation of Therapeutically Beneficial Fast Dissolving Tablet Containing Herbal Extracts: A Quality by Design Approach." Indian Journal of Science and Technology 18, no. 9 (2025): 682–95. https://doi.org/10.17485/IJST/v18i9.3480.

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<strong>Objectives:</strong> The QbD approach validates the formulation during development, ensuring therapeutic benefits through the careful selection of herbal extracts. <strong>Methods:</strong> Oral dosage forms, especially fast dissolving tablets with different herbal extracts (curcumin, saffron, and gingerol) were developed to get their desired therapeutic actions immediately. Quality by Design (QbD) emphasizes a science-based approach to product development. Design of Experiments (DOE) and ANOVA are used to analyze high-risk Critical Quality Attributes (CQAs). Design Expe

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25

Acharya, A., G. B. K. Kumar, P. Goudanavar, and K. Dhakal. "Various approaches to enhance the dissolution of Lornoxicam fast dissolving tablets prepared by using different categories of superdisintegrants: A comparative study." Journal of Manmohan Memorial Institute of Health Sciences 4, no. 1 (2018): 86–102. http://dx.doi.org/10.3126/jmmihs.v4i1.21147.

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Background: Recent developments in fast dissolving tablets have brought convenience in dosing to pediatric and elderly patients who have trouble in swallowing tablets.The main objective of the present study is to formulate fast dissolving tablet of Lornoxicam by direct compression method.Methods: Guar gum and crospovidone were used as natural and synthetic superdisintegrants respectively. Fast dissolving tablet of Lornoxicam were prepared by direct compression technique using three different approaches; superdisintegrant addition, sublimation, and solid dispersion.Results: IR and DSC studies s

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Nitish, Gaur* Rajan Kothari. "A comprehensive review on fast dissolving pantoprazole tablet: a promising approach for drug delivery." International Journal of Advances in Pharmacy Medicine and Bioallied Sciences 10, no. 3 (2022): 101–7. https://doi.org/10.5281/zenodo.7708959.

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Besides creating an easy-to-use dosage form for treatment, a revolutionary drug delivery system will increase the safety and effectiveness of therapeutic molecules and improve patient compliance. One such strategy resulted in the creation of fast-dissolving tablets. Fast-dissolving tablets (FDTs) are becoming more and more important today as a result of the variety of medications they can be used for. These are revolutionary tablet forms that dissolve/disperse/disintegrate in saliva in under 60 seconds without chewing or additional water. A popular proton-pump inhibitor (PPI) in clinics and ot

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K. Ahmed, Dua'a, and Balkis A. Kamal. "Formulation and Optimization of Oral Fast Dissolving Prochloperazine Maleate Tablets." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512) 21, no. 1 (2017): 46–55. http://dx.doi.org/10.31351/vol21iss1pp46-55.

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Prochloperazine maleate (PCM) is one of the most prescribed phenothiazine. The purpose of the present research was to develop fast dissolving tablets of PCM with Î²-cyclodextrin inclusion complex. Tablets prepared by wet granulation with sublimation and by using different superdisintegrants type [ low-hydroxypropylcellulose LH21 (L-HPC LH21), carboxymethylcellulose calcium (ECG505), crospovidone (CP)], and different type of subliming agents (urea and ammonium bicarbonate (AB)). Tablets evaluated for its % friability, disintegration time, wetting time, hardness, content uniformity, weight varia

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Palwinder, Singh* and Rajeev Garg. "FAST DISSOLVING ORAL FILMS: A NOVEL TREND IN DOSAGE FORM." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 05 (2018): 4571–78. https://doi.org/10.5281/zenodo.1256824.

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Oral routes are most commonly preferred route for drug delivery. Commonly used oral dosage forms are tablet and capsules. But many patients such as geriatric, paediatric and dysphasic patients find difficulty in swallowing conventional tablet and capsule. To overcome the problems related to swallowing, Fast dissolving Tablets (FDTs) were designed in early 19th century and hence further advancement has led to development of Fast Dissolving Oral Films (FDOFs). Many pharmaceutical groups are focusing their research on rapid dissolving technology. FDOFs technology is gaining much attention. This t

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Bhide, Prashant, and Reeshwa Nachinolkar. "FORMULATION DEVELOPMENT AND CHARACTERISATION OF MECLIZINE HYDROCHLORIDE FAST DISSOLVING TABLETS USING SOLID DISPERSION TECHNIQUE." International Journal of Applied Pharmaceutics 10, no. 4 (2018): 141. http://dx.doi.org/10.22159/ijap.2018v10i4.26493.

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Objective: The aim of the present investigation was to design and evaluate fast dissolving tablet (FDT) for the oral delivery containing solid dispersion of meclizine (MCZ) hydrochloride, an antiemetic drug.Methods: The solubility of meclizine was increased by preparing solid dispersions using mannitol as a carrier by fusion method. The prepared solid dispersion, was subjected for in vitro drug release, percent practical yield, drug content, infrared spectroscopy (IR), differential scanning calorimetry (DSC), scanning electron microscopy (SEM). Optimized solid dispersion was incorporated to pr

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Das, Pratik Swarup, Sushma Verma, and Puja Saha. "FAST DISSOLVING TABLET USING SOLID DISPERSION TECHNIQUE: A REVIEW." International Journal of Current Pharmaceutical Research 9, no. 6 (2017): 1. http://dx.doi.org/10.22159/ijcpr.2017v9i6.23435.

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Fast dissolving tablets are also called as mouth-dissolving tablets, melt-in mouth tablets, orodispersible tablets, quick dissolving etc. Fast dissolving tablets are those when put on tongue disintegrate instantaneously releasing the drug, which dissolve or disperses in the saliva. The faster the drug dissolved into solution, quicker the absorption and onset of clinical effect. Oral routes of drug administration have wide acceptance up to 50-60% of total dosage forms. Fast dissolving tablet containing solid dispersion was developed to improve the dissolution of drug and stability of solid disp

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Ansari, K. Kareemuddin, and Neeraj Sharma. "Formulation and evaluation of orodispersible tablets of lornoxicam." Journal of Drug Delivery and Therapeutics 8, no. 6 (2018): 225–28. http://dx.doi.org/10.22270/jddt.v8i6.2058.

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Orodispersible tablets (ODTs), also known as fast melt, quick melts, fast disintegrating have the unique property of disintegrating in the mouth in seconds without chewing and the need of water. The purpose of this investigation was to develop mouth dissolving tablets of Lornoxicam using KYRON T-314 (Polacrillin Potassium) as a novel superdisintegrant. Mouth dissolving tablets of lornoxicam were prepared by wet granulation technique using KYRON T-314 as superdisintegrant and menthol as subliming agent. The present study demonstrated potentials for rapid absorption, improved bioavailability, ef

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Rane, Devendra Revanand, Hemant Narhar Gulve, Vikas Vasant Patil, Vinod Madhaorao Thakare, and Vijay Raghunath Patil. "Formulation and evaluation of fast dissolving tablet of albendazole." International Current Pharmaceutical Journal 1, no. 10 (2012): 311–16. http://dx.doi.org/10.3329/icpj.v1i10.11848.

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Albendazole is broad spectrum anthelmintic use against many helminths. It is used for treatment of Threadworm, Hookworm, and Tapeworm. It has low bioavailability due to its first pass metabolism. In the present work, fast dissolving tablet of Albendazole was design with a view to and provide a quick onset of action. The main objective of the study was to formulate fast dissolving tablets of Albendazole to achieve a better dissolution rate and further improving the bioavailability of the drug. Fast dissolving tablets prepared by direct compression and using super disintegrants in different conc

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Singh, Kehar, Gaikwad Dushyant Dadabhau, and Satbir Singh. "Formulation Design and Development of Fast Disintegrating Tablets of Losartan Potassium By Using Locast Bean Gum As Superdisintigrants." International Journal of Membrane Science and Technology 10, no. 5 (2023): 1084–96. http://dx.doi.org/10.15379/ijmst.v10i5.3700.

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For patients who have trouble swallowing tablets, capsules, etc., fast dissolving drug delivery devices provide an option. Water is not necessary for the swallowing of fast dissolving pills because they dissolve instantly in the mouth. Using locust bean gum as a natural superdisintegrant, the present work set out to produce fast-dissolving tablets of losartan potassium. Perform pre formulation studies like partition coefficient, solubility and identification of drug. The influence of precompressional parameters like interaction studies and compatibility. Other tablet properties were examined,

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Gupta, Sparsh, Rakesh Roshan Mali, and Vashali Goel. "Novel study in fast dissolving drug delivery system: a review." Indian Journal of Pharmaceutical and Biological Research 3, no. 01 (2015): 93–107. http://dx.doi.org/10.30750/ijpbr.3.1.14.

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Novel drug delivery systems are becoming increasingly sophisticated as pharmaceutical scientists acquire a better understanding of the physicochemical and bio-chemical parameters pertinent to their performance. Despite tremendous advancements in drug delivery, the oral route remains the perfect route for the administration. Novel drug delivery system assists to achieve better patient compliance. Fast dissolving tablets are one of them.FDT have benefits such as accurate dosing, easy portability and manufacturing, good physical and chemical stability and an ideal alternative for pediatric and ge

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Dr., Dilip Agrawal, Ashok Kumar Sharma Mr., Rakesh Goyal Dr., Mukesh Bansal Dr., Mohit Khandelwal Mr., and Shaneza Aman Ms. "DEVELOPMENT AND EVALUATION OF FAST DISSOLVING TABLET OF ETORICOXIB BY USING NATURAL SUPERDISINTEGRANT (FENUGREEK POWDER)." International Journal of Current Pharmaceutical Review and Research 12, no. 4 (2020): 01–08. https://doi.org/10.5281/zenodo.12667356.

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The demands for fast dissolving tablets have received ever increasing day by day during thelast two decade. In the proposed present project study, the effect of natural Superdisintegrantswas compared with synthetic Super disintegrants and conventional Super disintegrants in theof fast dissolving tablet formulation of Etoricoxib. Etoricoxib NSAID is used for thetreatment of mild to moderate pain in various conditions like (osteoarthritis) and reducingpain, swelling, and joint stiffness caused with rheumatoid arthritis. In the present work 9formulations of FDT (Fast dissolving tablet) of Etorico

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Singhal, Peeush. "OPTIMIZED FAST DISINTEGRATING TABLETS, BOOSTED OSELTAMIVIR PHOSPHATE ORALLY FAST DISINTEGRATING TABLETS." Journal of Medical pharmaceutical and allied sciences 10, no. 6 (2021): 3781–88. http://dx.doi.org/10.22270/jmpas.v10i6.1479.

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Background Around 33% of the populace (fundamentally pediatric and geriatric) has gulping hardships, bringing about helpless consistence with oral tablet drug treatment which prompts decreased in general treatment viability. For this explanation, tablets that can quickly break down or deteriorate in the oral cavity have drawn in a lot of consideration. Objective research was designed to develop and evaluate boosted orally fast disintegrating tablets (OFDT) for oro-buccal drug delivery of oseltamivir phosphate. Methods In the present study six formulations of mouth dissolving tablet of oseltami

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Gandhi, Lavika, and Md Semimul Akhtar. "Formulation and Characterization of Mouth Dissolving Tablet of Antiepileptic Drug using Natural Superdisintegrants." Journal of Drug Delivery and Therapeutics 9, no. 3-s (2019): 673–78. http://dx.doi.org/10.22270/jddt.v9i3-s.2950.

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MDTs is regarding as a good candidates for the patients with persistent nausea, who are traveling, or who have little or no access to water. The objective of present research work was to prepare and evaluate the mouth dissolving tablet of Lacosamide using Super disintegrants like Guar Gum, and other excipients like Microcrystalline Cellulose and Mannitol in different concentrations by Direct Compression method. Lacosamide has been shown to be an effective antiepileptic agent appropriate for the epilepsy patients. Effect of different formulation variables i.e. amount of polymer and type of poly

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RADA, SANTOSH KUMAR, and Annu Kumari. "Fast dissolving tablets: waterless patient compliance dosage forms." Journal of Drug Delivery and Therapeutics 9, no. 1 (2019): 303–17. http://dx.doi.org/10.22270/jddt.v9i1.2292.

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Drug delivery by the oral route is the most prescribable and acceptable route in terms of patient’s compliance. Improvement of patient’s compliance has always a challenge towards the development of oral drug delivery system. In the market different types of oral dosage forms are available in which tablets, capsules, syrups, suspensions are preferred ones. Oral solid drug delivery faces drawback in case of swallowing especially with paediatrics and geriatric psychotic patients. Therefore scientists attracted towards fast mouth dissolving drug delivery systems to encounter existing problems with

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Mahajan, Uday, Bharat Parashar, Nikhi Sharma, Yogesh Jadhav, Sunny Musasvad, and Vishal Patil. "Fast Dissolving Tablet- An Overview of Formulation Technology." Indo Global Journal of Pharmaceutical Sciences 02, no. 02 (2012): 157–66. http://dx.doi.org/10.35652/igjps.2012.19.

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In recent years, a variety of pharmaceutical research has been conducted to develop new dosage forms. Among the dosage forms developed to facilitate ease of medication, the rapid disintegrating tablet (RDT) is one of the most widely employed commercial products. As our society is becoming increasingly aged, the development of Fast or mouth dissolving tablets have been formulated for pediatric, geriatric, and bedridden patients and for active patients who are busy and traveling and may not have access to water. Such formulations provide an opportunity for product line extension in the many elde

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Y., Shiva Kumar* Dr.T. Mangilal Dr. M. Ravi Kumar J. Naveen. "PREPARATION AND EVALUATION OF TAPENTADOL MOUTH DISSOLVING TABLETS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 04 (2019): 8726–36. https://doi.org/10.5281/zenodo.2656643.

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<em>Mouth dissolving tablets are solid dosage forms containing tapentadol as active pharmaceutical ingredient which has analgesic effect, and has superdistegrants like croscarmellose sodium and starch glycolate which disintegrates fast usually less than 60 seconds without the need of water when placed on the tongue. To prepare and evaluate tapentadol mouth dissolving tablet by using direct compression method  and to determine the effect of formulation process and the excipients. Tapentadol MDT were formulated by using ingredients and superdisintegrants like sodium starch glycolate and cro

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Asija, Dr Rajesh, Karishma Sharma, and Seema Yadav Trimukhe. "A Review on Development of Fast Dissolving Tablet and Approaches in Pharmaceutical Dosage of Atorvastatin." International Journal of Research and Review 9, no. 5 (2022): 15–22. http://dx.doi.org/10.52403/ijrr.20220504.

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Dosage form tablets and capsules in the current era still have gained considerable importance and acceptance by the formulation scientists, physicians, and the patients due to their numerous advantages which include easy self-administration and cost-effectiveness experienced by the patients. However, the drug delivery through the tablet dosage is no doubt, associated with potential drawbacks which include difficulty for the older and pediatric patients to swallow (dysphagia), low fraction of drug available for absorption in the bloodstream due to first-pass hepatic effect, and a slower therape

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Sathali, A. Abdul Hasan, R. Prabhu, P. Rahmathnisha, and S. Ponnammal Asmi. "FORMULATION DEVELOPMENT AND EVALUATION OF FAST DISSOLVING TABLETS OF TORSEMIDE." International Journal of Pharmaceutical Sciences and Medicine 7, no. 4 (2022): 1–17. http://dx.doi.org/10.47760/ijpsm.2022.v07i04.001.

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Hypertension is a chronic disease that is characterized by a persistently high blood pressure. It can cause strokes, myocardial infarctions, heart failure, and chronic kidney failure if not treated properly. An effort has been made to develop a fast dissolving tablet containing torsemide, which is used in the treatment of hypertension, in enhancing the onset of action, therapeutic response, patient acceptance, and ease of access. Torsemide fast dissolving tablets (FDTs) were prepared by direct compression method using different ratios of super-disintegrants. The prepared tablets were subjected

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Jain, Janak, Harshad Parmar, Anand Patel, and Vishnu Patel. "FAST DISSOLVING TABLET: THE NEW ERA." International Journal of Biomedical Research 1, no. 1 (2010): 06. http://dx.doi.org/10.7439/ijbr.v1i1.190.

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Achal, Chavan, Bharatee Chaudhary, Vivek Kumar Redasani, Pooja Bhagat, and Rutuja Mahadik. "On Overview of Fast dissolving tablet." Asian Journal of Pharmaceutical Research and Development 11, no. 3 (2023): 190–93. http://dx.doi.org/10.22270/ajprd.v11i3.1276.

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Fast dissolving tablets emerge as one of the popular and widely accepted dosage forms, especially for paediatric patients because of incomplete development of the muscular and nervous system and a case of geriatric patients suffering from Parkinson’s disorder or hand tremors. Few solid dosage forms like capsules and tablets are present days facing the problems like difficulty in swallowing (dysphagia), resulting in many incidences of non-compliance and making the therapy ineffective. Oral dosage form and oral route is the most preferred route of administration for various drugs have limitation

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Sagar, T. Malsane, S. Aher Smita, and B. Saudagar R. "A Review on Fast Dissolving Tablet." International Journal of Current Pharmaceutical Review and Research 9, no. 3 (2017): 284–92. https://doi.org/10.5281/zenodo.12674645.

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Oral route is presently the gold standard in the pharmaceutical industry where it is regarded as the safest, most economicaland most convenient method of drug delivery resulting in highest patient compliance. Over the past three decades, orallydisintegrating tablets (FDTs) have gained considerable attention due to patient compliance. Usually, elderly peopleexperience difficulty in swallowing the conventional dosage forms like tablets, capsules, solutions and suspensions becauseof tremors of extremities and dysphagia. In some cases such as motion sickness, sudden episodes of allergic attack orc

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Sagar, T. Malsane, S. Aher Smita, and B. Saudagar R. "A Review on Fast Dissolving Tablet." International Journal of Current Pharmaceutical Review and Research 8, no. 3 (2017): 284–92. https://doi.org/10.5281/zenodo.12677626.

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Oral route is presently the gold standard in the pharmaceutical industry where it is regarded as the safest, most economicaland most convenient method of drug delivery resulting in highest patient compliance. Over the past three decades, orallydisintegrating tablets (FDTs) have gained considerable attention due to patient compliance. Usually, elderly peopleexperience difficulty in swallowing the conventional dosage forms like tablets, capsules, solutions and suspensions becauseof tremors of extremities and dysphagia. In some cases such as motion sickness, sudden episodes of allergic attack orc

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Baijnath, Pal* Kavita Lovanshi Rita Mourya. "A Review on Fast Dissolving Tablet." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 3147–53. https://doi.org/10.5281/zenodo.15295648.

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The most common and preferred route of drug administration is through the oral route. Fast Dissolving tablets are gaining importance among novel oral drug-delivery system as they have improved patient compliance and have some additional advantages compared to other oral formulation. They are also solid unit dosage forms, which disintegrate in the mouth within a minute in the presence of saliva due to super disintegrants in the formulation. Thus this type of drug delivery helps a proper peroral administration in pediatric and geriatric population where swallowing is a matter of trouble. Various

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Aparna.P*, Subash Chandran M.P Jaghatha T. John Wesley I. Remya B.S. "A REVIEW ON FAST DISSOLVING TABLETS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 04 (2018): 2412–21. https://doi.org/10.5281/zenodo.1218253.

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Oral route is the most preferred route for administration of various drugs because it is regarded as safest, most convenient and economical route. Recently researchers developed the fast dissolving tablet (FDT) with improved patient compliance and convenience. FDTs are solid dosage forms which dissolve rapidly in saliva without chewing and additional water. FDTs overcome the disadvantages of conventional dosage form especially dysphagia (difficulty in swallowing) in pediatric and geriatric patients. This review includes ideal properties, characteristics, challenges in formulation, suitability

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Tiwari, Reshu, Mohd Haris Siddiqui, Tarique Mahmood, and Alvina Farooqui. "NEUROPROTECTIVE EFFECT OF POLYHERBAL FAST DISSOLVING TABLET OF CURCUMIN, QUERCETIN AND RUTIN AGAINST STREPTOZOTOCIN INDUCED DIABETIC NEUROPATHY IN RODANTS." International Journal of Advanced Research 11, no. 12 (2023): 704–19. http://dx.doi.org/10.21474/ijar01/18035.

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Purpose: In the Current study we conducted the neuroprotective effect of the Polyherbal combination of curcumin, quercetin and rutin in Streptozotocin-induced Diabetic neuropathy in diabetic rat. Method: In the 12 week study, two different formulations of polyherbal fast dissolving tablets were administered to diabetic rats. Neuropathic pain was assessed in diabetic rats with numerous aching trials and these tests were carried out for the consideration of thermal, mechanical, cold and hot hyperalgesia and nerve co-ordination. At the end of this study, trial animals were sacrificed and examined

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Siddhanshu, Jain, Khandelwal Mohit, Agrawal Dilip, and Goyal Rakesh. "DESIGN, DEVELOPMENT AND EVALUATION OF FAST DISSOLVING TABLET OF TIZANIDINE USING FENUGREEK SEED MUCILAGE." International Journal of Current Pharmaceutical Review and Research 14, no. 03 (2022): 108–12. https://doi.org/10.5281/zenodo.12658808.

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The demands for fast dissolving tablets have received ever increasing day by day during thelast decade. In the present projected study, the effect of natural superdisintegrant wascompared with synthetic super disintegrants and conventional super disintegrants in the offast dissolving tablet formulation of tizanidine Hcl. Tizanidine Hcl is a potent muscle relaxantwhich management of increased muscle tone associated with spasticity. In the present work12 formulations of FDT (Fast dissolving tablet) of tizanidine were prepared by using isolatedmucilage of fenugreek seed was evaluated and compiles

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