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1

Andoni, Lamis. "Fracas in Fateh." Journal of Palestine Studies 17, no. 2 (January 1, 1988): 198–99. http://dx.doi.org/10.2307/2536887.

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2

Andoni, Lamis. "Fracas in Fateh." Journal of Palestine Studies 17, no. 2 (January 1988): 198–99. http://dx.doi.org/10.1525/jps.1988.17.2.00p02065.

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3

Abbasi, N. S. "Syed Fateh Shah Abbasi." BMJ 327, no. 7423 (November 8, 2003): 1111—a—1112. http://dx.doi.org/10.1136/bmj.327.7423.1111-a.

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4

Trocchio, James T. "Investigation of Fateh Mishrif Fluid-Conductive Faults." Journal of Petroleum Technology 42, no. 08 (August 1, 1990): 1038–45. http://dx.doi.org/10.2118/17992-pa.

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5

PAGAN, NICHOLAS O. "Inside Fateh Azzam's Baggage: Monologue and Forced Migration." Theatre Research International 32, no. 1 (March 2007): 16–31. http://dx.doi.org/10.1017/s0307883306002483.

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The work of Palestinian playwright Fateh Samih Azzam arises from his experience growing up as a refugee and from his strong commitment to human rights. His latest play, Baggage, is set in a crowded airport where a lone Traveler re-enacts the Catastrophe of 1948 and its consequences. This article begins by positioning Azzam's work in relation to post-1948 Palestinian theatre. It then looks in detail at how Baggage, written as a monodrama, incorporates a number of devices including airport announcements and other voiceovers to imbue monologue with dialogue. The question of the relationship between monologue and dialogue is examined in the context of the emergence of the ‘political’ in performance and especially in relation to Jon Erickson's recent contention that dialogues facilitate the representation of conflicting world views whereas monologues tend to be ‘vehicles for the overarching world view of the playwright’. Next, it discusses a recent staging of Baggage in Famagusta, North Cyprus, focusing in particular on the way in which the production was able to embellish and extend devices contained in the written text of the play to facilitate a movement from monologue to dialogue. In its conclusion, the article returns to the prevalence of monologue in Palestinian drama and to Erickson's idea that monologue involves partiality to one side of a dispute. The article contends that productions of Baggage, which, like the one in Famagusta, accentuate the dialogical, will make it clear that the play is not just a memory play for Palestinians, but that it also cries out for all those forced out of their homes and into what Edward Saïd has called ‘the trauma of exile’. Furthermore, it argues that the Traveler's monologues need to be heard and should initiate dialogues, which in some parts of the world have not yet even begun. Finally, it suggests that the universal appeal of this and other Palestinian plays could be even more striking were the heavy use of politically oriented symbolism counterbalanced by a more minimalist Beckett-like aestheticism.
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6

Kubiciel, Michael. "Funktionen und Dimensionen der Strafrechtsvergleichung (Beck/Burchard/Fateh-Moghadam)." Rechtswissenschaft 3, no. 2 (2012): 212–22. http://dx.doi.org/10.5771/1868-8098-2012-2-212.

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7

Kalra, Virinder S. "Punjabiyat and the music of Nusrat Fateh Ali Khan." South Asian Diaspora 6, no. 2 (May 15, 2014): 179–92. http://dx.doi.org/10.1080/19438192.2014.912464.

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8

Singh, Kanika. "Commemorating Baghel Singh’s ‘Conquest’ of Delhi: The Fateh Diwas." Studies in History 36, no. 2 (August 2020): 280–301. http://dx.doi.org/10.1177/0257643020956625.

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This article examines the changing importance, in Sikh history, of Baghel Singh, a Sikh military commander in eighteenth-century Punjab, and the significance of the most recent events commemorating him in Delhi—the Fateh Diwas. The Fateh Diwas was a spectacular event organized for the first time in 2014 at the Red Fort in Delhi, by the Shiromani Akali Dal (SAD; Badal)-led Delhi Sikh Gurdwara Management Committee. It celebrated the conquest of Delhi by the Sikhs and the unfurling of the Sikh flag on the Red Fort by Baghel Singh. This claim is significant for its timing, symbolism and the historical legacy it seeks to remember. This representation of Baghel Singh also appears in modern paintings on Sikh history which are widely reproduced in popular spheres and also constitute the display in Sikh museums. A comparison of this particular representation of Baghel Singh with that in the nineteenth-century text, Sri Gur Panth Prakash by Ratan Singh Bhangu, is useful in understanding how Baghel Singh’s role has changed in Sikh history and how is it being deployed in contemporary heritage politics.
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9

Denes, Nick. "Between Form and Function." Middle East Journal of Culture and Communication 7, no. 2 (2014): 219–41. http://dx.doi.org/10.1163/18739865-00702008.

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In 1968, the first cinema unit of the Palestinian liberation movement was founded in Amman by Mustafa Abu Ali, Sulafa Jadallah and Hany Jawhariyyeh. Affiliated with Yasser Arafat’s rapidly ascendant Fateh movement, from 1969 to 1974 this organization completed a stylistically eclectic series of films addressing revolutionary changes in Palestinian society and politics. This essay identifies some of the more striking formal experiments undertaken in these early works, reading these in contact with historical and political conditions. It links a reading of the Fateh movement’s response to questions of political form or definition in this period, with an account of the aesthetic and structural innovations through which these early filmmakers pursued a cinema suited to the revolutionary moment. By distinguishing works of this early period from those that followed, and by highlighting the stylistic variations occurring in them, the essay shows filmmaking by militants affiliated with the liberation movement’s political establishment to have been more adventurous and formally unstable than has previously been suggested.
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10

Baud, Pierre-Alain. "Nusrat fateh ali khan: Le qawwali au risque de la modernité." Cahiers de musiques traditionnelles 9 (1996): 259. http://dx.doi.org/10.2307/40240603.

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11

Al-Azawi, Nagham Majeed, Ziyad Asmail Abed, and Mohammed Al-Issawi. "Detection of genes associated with qualitative characteristics of gluten." RUDN Journal of Agronomy and Animal Industries 14, no. 3 (December 15, 2019): 196–208. http://dx.doi.org/10.22363/2312-797x-2019-14-3-196-208.

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The research was aimed at analyzing allelic variants of protein in wheat varieties used in Iraqi bakery and evaluating these varieties via genetic source using grain quality selection. Variety tests were carried out at field experimental station of Russian State Agrarian University - Moscow Timiryazev Agricultural Academy. The analysis of wheat grain quality was made after harvesting in mid August. Allele state of genes controlling the quality of gluten in wheat grain was determined using the PCR method. Samples of Iraqi wheat varieties 12 (soft wheat) and One (durum wheat) are characterized by considerable variation of gluten content and quality. The five varieties whose genotype include an allelic variant of high molecular weight glutenins Glu-D1 5+10 and subunit Glu-A1-2* (Fateh, Tamuz-3, Abighreb-3, Iraq and Maxibak) were also studied. The highest gluten content was from 31.5 % in Iraq to 35.3 % in Fateh variety, while the gluten quality was not below the second group. Five varieties - Farah, AlMurug, Sham-6, Tahadi and Sabirbeg - had unusual combination of the allelic state of Glu-D1 2+12 (which is usually associated with low gluten quality) with a 2* subunit for the Glu-A1 locus, which determines the possibility of improving gluten quality to the wheat varieties.
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12

Cleanthis, Marcus, Gerard Stansby, and Jonathan Smout. "Comment on "Hyperresponsiveness of platelets in ischemic stroke" by Fateh-Moghadam et al." Thrombosis and Haemostasis 99, no. 01 (2008): 239. http://dx.doi.org/10.1160/th07-07-0467.

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عودة, نبيل. "الموقف الإسرائيلي من اتفاق المصالحة الفلسطينية لعام 2017 = Israeli Stance on Fateh - Hamas Reconciliation." مجلة دراسات شرق أوسطية 21, no. 82 (January 2018): 71–80. http://dx.doi.org/10.12816/0050609.

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14

Rawal, I., H. Joshi, and B. L. Chaudhary. "Water Quality Assessment Using Physicochemical and Bacteriological Parameters of Fateh Sagar Lake, Udaipur, India." Water Resources 45, no. 3 (May 2018): 427–35. http://dx.doi.org/10.1134/s0097807818030120.

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15

Talha Qadri, S. M., Bushra Nawaz, S. H. Sajjad, and Riaz Ahmad Sheikh. "Ambient noise H/V spectral ratio in site effects estimation in Fateh jang area, Pakistan." Earthquake Science 28, no. 1 (February 2015): 87–95. http://dx.doi.org/10.1007/s11589-014-0105-9.

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Balo, N. N., N. M. Shembesh, and R. Singh. "Maternal characteristics and infant and young child feeding in Benghazi." Eastern Mediterranean Health Journal 2, no. 3 (September 2, 2021): 432–39. http://dx.doi.org/10.26719/1996.2.3.432.

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Two hundred [200] mothers consecutively attending Al-Fateh Paediatric Hospital, Benghazi in 1992 were interviewed. The majority of women were under 30 years of age, had primary or no education, were housewives, had no experience of pregnancy wastage or child loss, used no contraception, had one to three living children, had information about breast-feeding from the mother-in-law, a relative or a neighbour, considered breast-feeding a natural way, nutritionally superior and hygienic, and practised mixed feeding. The reasons for introducing artificial feeding were maternal in 49.7% of cases, filial [related to the baby] in 36.5% and due to social pressure in 13.8%. Measures for successful breast-feeding are emphasized
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17

Shembesh, Nuri M., Nura Naseb M. Balo, and Ratan Singh. "Breast-feeding and weaning patterns in Benghazi, Libyan Arab Jamahiriya." Eastern Mediterranean Health Journal 3, no. 2 (March 15, 1997): 251–57. http://dx.doi.org/10.26719/1997.3.2.251.

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An interview survey of 200 mothers attending the emergency service of Al-Fateh Paediatric Hospital, Benghazi, showed that prelacteal feed was given to 18.5% of babies and breast-feeding was ever initiated in 90.5%. After three months exclusive breast-feeding was continued in less than 30%, mixed feeding in 44%-71% and supplementary feeding [with and without breast-feeding] in 65%-97%. Locally consumed food like fruit juice, vegetables, cooked rice and cereals and boiled eggs in mashed form were used as supplementary foods. No association was revealed between the type of feeding and childhood episodes of any illness, including diarrhoea or acute respiratory infection. Measures for prolonged breast-feeding, substitute artificial feeding [when indicated] and supplementary feeding are suggested
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18

Bishara, Fahad Ahmad. "The Many Voyages of Fateh Al-Khayr: Unfurling the Gulf in the Age of Oceanic History." International Journal of Middle East Studies 52, no. 3 (June 17, 2020): 397–412. http://dx.doi.org/10.1017/s0020743820000367.

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AbstractIn this article, I make the claim that the time has come to re-situate the Gulf historically as part of the Indian Ocean world rather than the terrestrial Middle East. I explore the historical potential of thinking “transregionally” – of what it means to more fully weave the history of the Gulf into that of the Indian Ocean, and what the ramifications are for orienting it away from the terrestrially-grounded literature in which it has long been situated. The promise of an oceanic history, I argue, is both academic and political: first, it opens up the possibilities of new narratives for the Gulf’s past, suggesting new periodizations, fruitful avenues of historical inquiry, and new readings of old sources. But more than that, an oceanic history of the Gulf allows historians to push against the discourses of nativism that have pervaded the public sphere in the Gulf States.
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19

Uddin, Md Helal, Sirazunnesa, Muhammad Shahidul Haq, Zoarder Faruque Ahmed, Jannatul Fatema, and Mst Kaniz Fatema. "Structural performance of fish market in Bogura district, Bangladesh." Research in Agriculture Livestock and Fisheries 5, no. 3 (December 31, 2018): 399–410. http://dx.doi.org/10.3329/ralf.v5i3.39589.

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One of the most important blossom trades in the economy of Bangladesh is fish marketing. To understand the current practices of fish market and marketing systems in Bogura district of Bangladesh, an investigation was conducted based on existing marketing system and economic features of marketing activities and inefficiencies. Fish marketing is almost exclusively maintained by the private sector and large number of intermediaries such as local traders, agents/suppliers, and retailers are involved in the distribution process of fish marketing. Data were collected from 45 fish traders through questionnaire interviews and participatory rural approach methods during December 2011 to May 2012 from three different fish markets named as Fateh Ali Fish Market, Godarpara Fish market and Khandar Fish market of Bogura district. The daily supply of fish in Fateh Ali Fish market, Godarpara Fish market and Khandar Fish market were estimated at 6.75 tons, 0.765 tons and 0.495 tons, respectively. Present supply and requirement of the fish showed a wide gap and virtually most of the fish (85%) is imported from outside where the local supply of fish is only 15%. There is a high consumer preference for Indian major carps i.e. rohu, catal, mrigal and exotic carps silver carp, grass and common carp, tilapia, pangas etc. The price of fish depends on market structure, species, quality, size, weight and season that’s why a well-systematized marketing setup is crucial for reasonable price for fishes. The study revealed that almost all traders in three markets made a considerable amount of profit and broadly improved their food consumption facilities, standards of living, purchasing power, choice and ability as an economic sector. However concerns arise about the sustainable marketing system due to higher transport costs, poor transport facilities, inadequate supply of ice, lack of money for business, and poor institutional support. It is an urgent issue to establish ice factory, improvement of transport facilities, provision of governmental, institutional and banking assistance, introduction of fish quality control measures and training of fish market operators for improved their marketing system. Therefore, the present study emphasizes the fundamental marketing system, market flow of fish, availability of fish in these three markets, and market related constraints in Bogura district, Bangladesh. Res. Agric., Livest. Fish.5(3): 399-410, December 2018
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20

Tariq, Aqil, Hong Shu, Saima Siddiqui, Muhammad Imran, and Muhammad Farhan. "Monitoring Land Use And Land Cover Changes Using Geospatial Techniques, A Case Study Of Fateh Jang, Attock, Pakistan." GEOGRAPHY, ENVIRONMENT, SUSTAINABILITY 14, no. 1 (April 5, 2021): 41–52. http://dx.doi.org/10.24057/2071-9388-2020-117.

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Change of land use and land cover (LULC) has been a key issue of natural resource conservation policies and environmental monitoring. In this study, we used multi-temporal remote sensing data and spatial analysis to assess the land cover changes in Fateh Jhang, Attock District, Pakistan. Landsat 7 (ETM+) for the years 2000, 2005 and 2010 and Landsat 8 (OLI/TIRS) for the year 2015 were classified using the maximum likelihood algorithms into built-up area, barren land, vegetation and water area. Post-classification methods of change detection were then used to assess the variation that took place over the study period. It was found that the area of vegetation has decreased by about 176.19 sq. km from 2000 to 2015 as it was converted to other land cover types. The built-up area has increased by 5.75%. The Overall Accuracy and Kappa coefficient were estimated at 0.92 and 0.77, 0.92 and 0.78, 0.90 and 0.76, 0.92 and 0.74, for the years 2000, 2005, 2010 and 2015, respectively. It turned out that economic development, climate change and population growth are the main driving forces behind the change. Future research will examine the effects of changing land use types on Land Surface Temperature (LST) over a given time period.
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Izadbakhsh, Alireza, and Payam Kheirkhahan. "An alternative stability proof for “Adaptive type-2 fuzzy estimation of uncertainties in the control of electrically flexible-joint robots”." Journal of Vibration and Control 25, no. 5 (October 3, 2018): 977–83. http://dx.doi.org/10.1177/1077546318802694.

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This short note points out an improvement on the robust stability analysis for electrically driven flexible joint robots (EDFJR) given in the 2017 paper by Zirkohi and Fateh, entitled “Adaptive type-2 fuzzy estimation of uncertainties in the control of electrically flexible-joint robots.” In their paper, the authors present an interval Type-2 Adaptive fuzzy control scheme for EDFJR. The nonlinearities associated with actuator input constraints have been also considered in their paper. They discussed the saturated and unsaturated region of the control input separately and neglected the transition state between these regions. Moreover, they did not guarantee the stability of the closed-loop system in the saturated area. In this note, an alternative stability proof is presented that does not require this separation, and which guarantees the stability in a more general framework. The overall closed-loop system is proven to be robust, and bounded-input, bounded-output stable, while the motor/joint position errors are uniformly-ultimately bounded based on the Lyapunov's stability concept.
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22

Soloshcheva, Maria A. "The Uyghur Terrorism: Phenomenon and Genesis." Iran and the Caucasus 21, no. 4 (December 23, 2017): 415–30. http://dx.doi.org/10.1163/1573384x-20170408.

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The aim of this paper is 1) to analyse the historical and political roots of the current situation in Xinjiang; 2) to identify the boundaries that separate the legal opposition from what is usually called non-system opposition; and 3) to study a set of preconditions that have affected the emergence of the phenomenon of the Uyghur terrorism. In a broader sense, the engagement of the Uyghur population in separatist activities under the slogan of the most radical Islamic religious-political movements (Jabhat an-Nusra (alias Jabhat Fateh al-Sham), ISIL, Al Qaeda, the Taliban, etc.) is addressed. Generally, the author tries to answer the following questions: What are the motives and methods of Uyghur terrorists? What dynamics of their violent acts may we consider in the People’s Republic of China and abroad? What legal and terrorist organisations have Chinese Uyghurs as members? And what distinguishes legal and the so called non-system Uyghur opposition?
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23

Rehman, Obaid Ur, Muhammad Rashid, Rahina Kausar, Sarosh Alvi, and Riaz Hussain. "Slope Gradient and Vegetation Cover Effects on The Runoff and Sediment Yield in Hillslope Agriculture." Turkish Journal of Agriculture - Food Science and Technology 3, no. 6 (April 22, 2015): 478. http://dx.doi.org/10.24925/turjaf.v3i6.478-483.292.

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Cultivation of field crops is a challenge and risky business in sloping areas. A study was conducted as a demonstration model for the sloppy lands of Fateh Jang, Pakistan. The objectives of this study were to monitor the runoff water and soil sediment loss under different vegetative covers and slope gradients in comparison with bare fallow on each slope gradient. Three artificial slope gradients i.e., 1%, 5% and 10% were established and three crops i.e., Wheat, Gram and Lentil were cultivated on each slope gradient. Soil and water losses were quantified against each slope gradient and every cover crop for the period of 4 years. Total soil sediment losses during this study were 51% in Lentil, 30% in Gram and 25% in Wheat were lesser compared with bare soil whereas, water losses from Lentil, Gram and Wheat were 69%, 75% and 73% lesser respectively while compared with bare plots. The highest soil and water losses were monitored at 10% slope gradient following 5% and then 1% slope gradients respectively.
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Chishty, Nadim, Anil Tripathi, and Madhusudan Sharma. "Evaluation of acute toxicity of zinc, lead and cadmium to zooplanktonic community in upper Berach river system, Rajasthan, India." South Asian Journal of Experimental Biology 2, no. 1 (March 19, 2012): 20–26. http://dx.doi.org/10.38150/sajeb.2(1).p20-26.

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Current study investigated through static bioassay, the acute toxicity of Zinc,Lead and Cadmium to fresh water zooplankters in the upper Berach riversystem which is a part of Gangetic river system. The river basin stretchesfrom Madar tank to Sarjana tank with a total length of 46 Km, including ninewater bodies i.e. Bada madar tank (73‹36f0ffE and 24‹38f0hN ), Chhotamadar tank, Fateh sagar lake, Udaisagar lake, Up]stream pond (Bichhdi]I),Down]stream pond(Bichhdi]II), Gadwa, Daroli and Sarjana tank (73‹ 57f10hEand 24‹14f30h N). Whole zooplanktonic communities were exposed to different heavy metal stresses. Exposed zooplanktonic community included nine planktonic forms i.e. Heliodiaptomus viduus, Mesocyclops hyalinus, Heterocypris, Daphnia lumholtzi, Moina, Brachionus, Monostyla, Filinia. Cadmium was found to be most toxic and Zinc was least toxic to zooplankton. Ostracods and Cyclops were resistant forms and rotifers were sensitive forms in relation to metallic exposure. Sensitivity pattern observed during laboratory experiments was found to be in accordance with biodiversity variation of zooplankton in different ponds of Berach river system.
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25

Abdalla, Adam, and NosybaAwad Said Taha. "THE PREVALENCE OF VITAMIN A DEFICIENCY AMONG CHILDREN BETWEEN 6- 9 YEARS OLD, EL FATEH QURAN SCHOOL, OMDURMAN LOCALITY, KHARTOUM STATE, SUDAN." International Journal of Research -GRANTHAALAYAH 4, no. 4 (April 30, 2016): 97–102. http://dx.doi.org/10.29121/granthaalayah.v4.i4.2016.2760.

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There is a substantial documentation of prevalence, severity and health consequences of vitamin A deficiency (VAD) in preschool-aged children, very few studies have been done to find out the extent of VAD among Quran pupils. This was a cross-sectional descriptive analytical study conducted in Elfateh Quran School, Omdurman locality. The objectives were to measure the prevalence of Xerophthalmia among Quran pupils in El-Fateh city and to relate it with socio demographic factors. All students between 6 to 9 years age in ELfatih Quran pupils were considered as target of this study, total coverage was done during the study period from(august to October)2012, and they were 220 students. Data was collected by using a questionnaire and eye examination to all students targeted age group. Data analyzed by using SPSS programs. The study found that the prevalence of VAD was 19.1%, of which 18.2% among boys which is significantly lowers than 0.9% among girls. The prevalence of night blindness was 7.3%, Bitots spots were 4.1%, corneal xerosis 5% and 2.7% were night blindness ± eye sign. The study concluded that the prevalence of VAD among study population was (19.1%). Institutional caregivers should be made aware of the importance of providing a balanced diet rich in vitamin A. They should also be aware of the signs and symptoms of VAD for early detection of xerophthalmia and hence take measures of early treatments.
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Manan, A., B. Shahid, A. Sultan, and U. I. Ahmed. "Consumer Demand for Beverages in Pakistan." Cercetari Agronomice in Moldova 50, no. 2 (June 1, 2017): 109–20. http://dx.doi.org/10.1515/cerce-2017-0020.

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AbstractThis current research endeavors to study important factors having significant impact on consumer’s choice of beverages in Punjab province of Pakistan. Beverages in two major categories of ‘hot’ and ‘cold’ have been studied to examine consumer consumption pattern. Data has been collected through interview from 80 respondents belonging to two major cities of Punjab, i.e. Lahore and Faisalabad, by incorporating stratified random sampling technique. These two cities of Punjab were selected because of big departmental stores opening like Metro Cash and Carry store, Al-Fateh and others. A pre tested and well-arranged questionnaire was used for data gathering from respondents. To estimate the outcome of factors affecting choices of consumers (demand function), multivariate analysis was incorporated. Results of this research showed that consumption pattern of cold beverages was affected significantly by consumer income, cold beverages prices, city selected for survey and number of adolescents in a family, whereas factors which affected the consumption of hot beverages were food expenditure, living area, marital status, income, working persons in a family, family size. Due to availability of copious brands of beverages, consumption is escalating with the passage of time and consumers are eager to pay but owing to high rates they are not relishing full taste of beverages. So, local industry should produce cost effective and quality drinks to enhance usage.
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27

Perrin, l. "More Than 30% HCV Prevalence in the HIV-1 El-Fateh Children Hospital Outbreak is a Key for Both Elucidation and Public Health Measures." Libyan Journal of Medicine 2, no. 2 (2007): 55–56. http://dx.doi.org/10.4176/070219.

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Perrin, Luc. "More than 30% HCV prevalence in the HIV-1 El-Fateh children hospital outbreak is a key for both elucidation and public health measures." Libyan Journal of Medicine 2, no. 2 (January 2007): 55–56. http://dx.doi.org/10.3402/ljm.v2i2.4694.

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29

Sparks, John. "Tiger: Portrait of a PredatorValmik Thapar, photographs by Gunter Ziesler and Fateh Singh Rathore Collins, London, 1986, 200 pp and 170 photographs, HB £15." Oryx 21, no. 2 (April 1987): 131. http://dx.doi.org/10.1017/s0030605300026776.

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30

Neumann, Ulfrid. "Fateh-Moghadam, Bijan: Die religiös-weltanschauliche Neutralität des Strafrechts. Zur strafrechtlichen Beobachtung religiöser Pluralität. Mohr Siebeck, Tübingen 2019. XIII, Jus Poenale 16, 438 Seiten." Zeitschrift für die gesamte Strafrechtswissenschaft 132, no. 2 (September 11, 2020): 441–52. http://dx.doi.org/10.1515/zstw-2020-0015.

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31

Heger, Martin. "Fateh-Moghadam, Bijan: Die religiös-weltanschauliche Neutralität des Strafrechts. Zur strafrechtlichen Beobachtung religiöser Pluralität (Jus Poenale, Bd. 16). Tübingen: Mohr Siebeck. 2019. XIV und 43." Zeitschrift für evangelisches Kirchenrecht 66, no. 3 (2021): 324. http://dx.doi.org/10.1628/zevkr-2021-0035.

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32

Gaind-Krishnan, Sonia. "Qawwali Routes: Notes on a Sufi Music’s Transformation in Diaspora." Religions 11, no. 12 (December 21, 2020): 685. http://dx.doi.org/10.3390/rel11120685.

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In recent years, alongside the concurrent rise of political Islam and reactionary state policies in India, Sufism has been championed as an “acceptable” form of Islam from neoliberal perspectives within India and the Western world. Sufism is noted as an arena of spiritual/religious practice that highlights musical routes to the Divine. Among Chishti Sufis of South Asia, that musical pathway is qawwali, a song form that been in circulation for over seven centuries, and which continues to maintain a vibrant sonic presence on the subcontinent, both in its ritual usage among Sufis and more broadly in related folk and popular iterations. This paper asks, what happens to qawwali as a song form when it circulates in diaspora? While prominent musicians such as the Sabri Brothers and Nusrat Fateh Ali Khan exposed audiences in the West to the sounds of qawwali, in recent years, non-hereditary groups of musicians based in the US and UK have begun to perform songs from the qawwali repertoire. In the traditional setting, textual meaning is paramount; this paper asks, how can performers transmute the affective capacity of qawwali in settings where semantic forms of communication may be lost? How do sonic and metaphorical voices lend themselves to the circulation of sound-centered meaning? Through a discussion of the Sufi sublime, this paper considers ways sonic materials stitch together the diverse cloth of the South Asian community in diaspora.
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Ambros, V. "Cell cycle-dependent sequencing of cell fate decisions in Caenorhabditis elegans vulva precursor cells." Development 126, no. 9 (May 1, 1999): 1947–56. http://dx.doi.org/10.1242/dev.126.9.1947.

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In Caenorhabditis elegans, the fates of the six multipotent vulva precursor cells (VPCs) are specified by extracellular signals. One VPC expresses the primary (1 degrees) fate in response to a Ras-mediated inductive signal from the gonad. The two VPCs flanking the 1 degrees cell each express secondary (2 degrees) fates in response to lin-12-mediated lateral signaling. The remaining three VPCs each adopt the non-vulval tertiary (3 degrees) fate. Here I describe experiments examining how the selection of these vulval fates is affected by cell cycle arrest and cell cycle-restricted lin-12 activity. The results suggest that lin-12 participates in two developmental decisions separable by cell cycle phase: lin-12 must act prior to the end of VPC S phase to influence a 1 degrees versus 2 degrees cell fate choice, but must act after VPC S phase to influence a 3 degrees versus 2 degrees cell fate choice. Coupling developmental decisions to cell cycle transitions may provide a mechanism for prioritizing or ordering choices of cell fates for multipotential cells.
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Manolis, James C., David E. Andersen, and Francesca J. Cuthbert. "Uncertain Nest Fates in Songbird Studies and Variation in Mayfield Estimation." Auk 117, no. 3 (July 1, 2000): 615–26. http://dx.doi.org/10.1093/auk/117.3.615.

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Abstract Determining whether nesting attempts are successful can be difficult. Yet, current protocols for estimating nesting success do not address how uncertain nest fates should be handled. We examined the problem of nest-fate uncertainty as it relates to Mayfield estimation of nesting success and in analyses of factors that influence success. We used data from Minnesota to illustrate the potential effect of uncertain fate; 40% of Ovenbird (Seiurus aurocapillus; n = 127) nests and 30% of Least Flycatcher (Empidonax minimus; n = 144) nests had uncertain fates. How this uncertainty is incorporated into Mayfield estimates of success varied widely among researchers. In a survey of researchers who use the Mayfield method, 9 of 22 respondents (of 40 contacted) excluded nests with uncertain fate. Excluding uncertain fates is counter to how Mayfield first described his estimator and can result in severe downward bias. The remaining respondents (59%) included nests with uncertain fate but varied in how they terminated the exposure period. We developed a simulation model that calculated Mayfield estimates using different approaches and compared them with a known rate of nesting success. Magnitude of bias in Mayfield estimates varied considerably in our simulations. The approach with the least bias terminated exposure with the last observed active date for nests with uncertain fate, and with the midpoint between last observed active and first observed inactive dates for nests with known fate. In addition, information necessary to interpret and compare Mayfield estimates often is not reported. These values, including variance estimates and the period lengths used to estimate survival rates, should be reported with Mayfield estimates. Finally, nest fate is commonly used as a categorical variable in studies of factors affecting nesting success. In this approach, however, nests with uncertain fate must be excluded. An alternative approach is Cox regression, which incorporates nests with uncertain fate.
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Chamberlin, H. M., and P. W. Sternberg. "Multiple cell interactions are required for fate specification during male spicule development in Caenorhabditis elegans." Development 118, no. 2 (June 1, 1993): 297–324. http://dx.doi.org/10.1242/dev.118.2.297.

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The B blast cell divides postembryonically in C. elegans males to produce 47 progeny that include all of the cells of the copulatory spicules. During the early development of the B lineage, the anterior daughter of B, B.a, generates eight cells. These cells migrate to form four pairs of cells that flank the developing cloaca (ventral, dorsal, and two identical lateral pairs). For each pair, the more anterior cell produces a distinct lineage ('anterior fate') from the posterior cell ('posterior fate'). For the ventral and dorsal pairs, either cell can migrate to the anterior position and produce the anterior lineage, and the other cell migrates posterior and produces the posterior lineage (Sulston and Horvitz, 1977, Dev. Biol. 56, 110–156). The migration is variable, although the resultant fate pattern is invariant. In the two lateral pairs, both the migration and fate pattern are invariant. Using a laser microbeam to selectively ablate neighboring cells we have found that the cells of the lateral pair also respond to positional cues. For all four pairs other male-specific blast cells provide extracellular cues. In general, F and U promote anterior fates, Y promotes some posterior fates, and the B.a progeny promote posterior fates. Several of these cues are redundant. By ablating combinations of cells we have deduced how these signals may act in concert to specify the fates of the B.a progeny. We propose that fate specification in these pairs depends on three general classes of extracellular cues: positional cues, modulators of positional cues, and lateral signals. The B lineage thus provides an opportunity to study with single cell resolution the integration of multiple intercellular signals.
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Kang, Jinjoo, Jaehyuk Yoo, Sunju Lee, Wanli Tang, Berenice Aguilar, Swapnika Ramu, Inho Choi, et al. "An exquisite cross-control mechanism among endothelial cell fate regulators directs the plasticity and heterogeneity of lymphatic endothelial cells." Blood 116, no. 1 (July 8, 2010): 140–50. http://dx.doi.org/10.1182/blood-2009-11-252270.

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Abstract Arteriovenous-lymphatic endothelial cell fates are specified by the master regulators, namely, Notch, COUP-TFII, and Prox1. Whereas Notch is expressed in the arteries and COUP-TFII in the veins, the lymphatics express all 3 cell fate regulators. Previous studies show that lymphatic endothelial cell (LEC) fate is highly plastic and reversible, raising a new concept that all 3 endothelial cell fates may coreside in LECs and a subtle alteration can result in a reprogramming of LEC fate. We provide a molecular basis verifying this concept by identifying a cross-control mechanism among these cell fate regulators. We found that Notch signal down-regulates Prox1 and COUP-TFII through Hey1 and Hey2 and that activated Notch receptor suppresses the lymphatic phenotypes and induces the arterial cell fate. On the contrary, Prox1 and COUP-TFII attenuate vascular endothelial growth factor signaling, known to induce Notch, by repressing vascular endothelial growth factor receptor-2 and neuropilin-1. We show that previously reported podoplanin-based LEC heterogeneity is associated with differential expression of Notch1 in human cutaneous lymphatics. We propose that the expression of the 3 cell fate regulators is controlled by an exquisite feedback mechanism working in LECs and that LEC fate is a consequence of the Prox1-directed lymphatic equilibrium among the cell fate regulators.
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Hill, Russell J., and Paul W. Sternberg. "Cell fate patterning during C. elegans vulval development." Development 119, Supplement (December 1, 1993): 9–18. http://dx.doi.org/10.1242/dev.119.supplement.9.

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Precursor cells of the vulva of the C. elegans hermaphrodite choose between two vulval cell fates (1° and 2°) and a non-vulval epidermal fate (3°) in response to three intercellular signals. An inductive signal produced by the anchor cell induces the vulval precursors to assume the 1° and 2° vulval fates. This inductive signal is an EGF-like growth factor encoded by the gene lin-3. An inhibitory signal mediated by lin-15, and which may originate from the surrounding epidermis, prevents the vulval precursors from assuming vulval fates in the absence of the inductive signal. A short range lateral signal, which acts through the gene lin-12, regulates the pattern of 1° and 2° fates assumed by the induced vulval precursors. The combined action of the three signals precisely directs the six vulval precursors to adopt a 3° 3° 2° 1° 2 ° 3° pattern of fates. The amount of inductive signal produced by the anchor cell appears to determine the number or vulval precursors that assume vulval fates. The three induced vulval precursors most proximal to the anchor cell are proposed to adopt the 2° 1° 2° pattern of fates in response to a gradient of the inductive signal and also in response to lateral signalling that inhibits adjacent vulval precursor cells from both assuming the 1° fate.
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38

Shabnam Bibi and Muhammad Hameed Nawaz. "A Study on the Effect of Emerging Technology on Students' Academic Achievements at Secondary Level." Journal of Business and Social Review in Emerging Economies 6, no. 1 (March 31, 2020): 365–78. http://dx.doi.org/10.26710/jbsee.v6i1.1088.

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The rapid growth in the use of technology particularly the use of emerging technologies has provided an opportunity to educators around the world to investigate the most suitable learning environments and more effective related material that would cater students’ diverse learning styles and knowledge. Therefore, the aim of the present study was “a study on the effect of emerging technology on students’ academic achievements at secondary level”. The sampling population of the present study is all students of grade 10 who are studying in public high school in Punjab. Use of emerging technology and its experiment was delimited to Biology students of class 10th in Govt Girls High School No1 Fateh Jang (Attock) sessions 2016-17 and its experiments was delimited to four chapters of Biology textbook. This study sought to discover that learning through emerging technology improved student academic achievement. Two different methods of instruction were employed for this research study. The first method of instruction was the traditional lecture and whiteboard method. The second method of instruction was the use of technological instruction. Students of 10th class in subject Biology were studied. Two groups controlled and experimental was selected on the basis of pre test to equate the knowledge level for experiment. For item analysis, researcher used SPSS, Mean. Overall the achievements of students were satisfactory. After analysis of the data conclusions were drawn that there is major difference between the students of experimental post and control post. The mean score of experimental post students is greater than control post. It is recommended that Teachers should use Emerging Technology based teaching aids like computer animations etc. to develop student’s interest in the subject for maximum teaching learning out-comes.
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BHATTI, MOHAMMAD AYAZ, and SHABBIR AHMAD KHAN. "HEALTH FACILITIES (BHUS)." Professional Medical Journal 12, no. 04 (December 31, 2005): 357–63. http://dx.doi.org/10.29309/tpmj/2005.12.04.5081.

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Objective: To measure the distance of villagesfrom the facility (BHU) and to analyze the geographical location, Pattern of Access and health facility utilization. StudyPurpose: To improve the health status of community, by improving the geographical patterns of access and healthfacility utilization in Pakistan and to provide necessary information to policy makers, planners and health care providersfor improvement of health facility utilization in Pakistan. Study Design: A cross sectional study. Setting: At UnionCouncil Gali Jagir, Tehsil Fateh Jang, District Attock. Period: From 15 Nov 1999 to 31 Dec 2000. Material & Method:Measurement of the distance from the villages to the health facility and the facility record was reviewed to assess theutilization pattern by the village population. Information about mode of travel, time for travel and cost of traveling wascollected by the key informers. Results: 22% of villages and 23% of population was situated at a distance of 3km fromthe BHU. 33% of villages and 30% of population were living within 5km. 67% of villages and 70% of population wassituated at a distance of more than 5km from BHU.The overall health facility utilization of BHU Gali Jagir is 8.34%.Discussion: The health facility utilization decreases as the distance increases. Geographical accessibility up to adistance of 3km is a new finding in the study. We have noted that majority of the villages and populations, 67% villagesand 70% population is uncovered and 33% villages’ and 30%population is under served. Conclusion: The study hasidentified the gaps in the geographical access patterns that an accessible distance is 3km instead of 5km (as acceptedby world health organization). Distance of 3km was accessible for seeking care from a public health care facility. Theover all health facility utilization was 8.32 %, which was alarmingly low.
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40

Corral-Martínez, Patricia, Charlotte Siemons, Anneke Horstman, Gerco C. Angenent, Norbert de Ruijter, and Kim Boutilier. "Live Imaging of embryogenic structures in Brassica napus microspore embryo cultures highlights the developmental plasticity of induced totipotent cells." Plant Reproduction 33, no. 3-4 (July 10, 2020): 143–58. http://dx.doi.org/10.1007/s00497-020-00391-z.

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Key message In vitro embryo development is highly plastic; embryo cell fate can be re-established in tissue culture through different pathways. Abstract In most angiosperms, embryo development from the single-celled zygote follows a defined pattern of cell divisions in which apical (embryo proper) and basal (root and suspensor) cell fates are established within the first cell divisions. By contrast, embryos that are induced in vitro in the absence of fertilization show a less regular initial cell division pattern yet develop into histodifferentiated embryos that can be converted into seedlings. We used the Brassica napus microspore embryogenesis system, in which the male gametophyte is reprogrammed in vitro to form haploid embryos, to identify the developmental fates of the different types of embryogenic structures found in culture. Using time-lapse imaging of LEAFY COTYLEDON1-expressing cells, we show that embryogenic cell clusters with very different morphologies are able to form haploid embryos. The timing of surrounding pollen wall (exine) rupture is a major determinant of cell fate in these clusters, with early exine rupture leading to the formation of suspensor-bearing embryos and late rupture to suspensorless embryos. In addition, we show that embryogenic callus, which develops into suspensor-bearing embryos, initially expresses transcripts associated with both basal- and apical-embryo cell fates, suggesting that these two cell fates are fixed later in development. This study reveals the inherent plasticity of in vitro embryo development and identifies new pathways by which embryo cell fate can be established.
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41

Wu, Chudong, Jean-François Boisclair Lachance, Michael Z. Ludwig, and Ilaria Rebay. "A context-dependent bifurcation in the Pointed transcriptional effector network contributes specificity and robustness to retinal cell fate acquisition." PLOS Genetics 16, no. 11 (November 30, 2020): e1009216. http://dx.doi.org/10.1371/journal.pgen.1009216.

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Spatiotemporally precise and robust cell fate transitions, which depend on specific signaling cues, are fundamental to the development of appropriately patterned tissues. The fidelity and precision with which photoreceptor fates are recruited in the Drosophila eye exemplifies these principles. The fly eye consists of a highly ordered array of ~750 ommatidia, each of which contains eight distinct photoreceptors, R1-R8, specified sequentially in a precise spatial pattern. Recruitment of R1-R7 fates requires reiterative receptor tyrosine kinase / mitogen activated protein kinase (MAPK) signaling mediated by the transcriptional effector Pointed (Pnt). However the overall signaling levels experienced by R2-R5 cells are distinct from those experienced by R1, R6 and R7. A relay mechanism between two Pnt isoforms initiated by MAPK activation directs the universal transcriptional response. Here we ask how the generic Pnt response is tailored to these two rounds of photoreceptor fate transitions. We find that during R2-R5 specification PntP2 is coexpressed with a closely related but previously uncharacterized isoform, PntP3. Using CRISPR/Cas9-generated isoform specific null alleles we show that under otherwise wild type conditions, R2-R5 fate specification is robust to loss of either PntP2 or PntP3, and that the two activate pntP1 redundantly; however under conditions of reduced MAPK activity, both are required. Mechanistically, our data suggest that intrinsic activity differences between PntP2 and PntP3, combined with positive and unexpected negative transcriptional auto- and cross-regulation, buffer first-round fates against conditions of compromised RTK signaling. In contrast, in a mechanism that may be adaptive to the stronger signaling environment used to specify R1, R6 and R7 fates, the Pnt network resets to a simpler topology in which PntP2 uniquely activates pntP1 and auto-activates its own transcription. We propose that differences in expression patterns, transcriptional activities and regulatory interactions between Pnt isoforms together facilitate context-appropriate cell fate specification in different signaling environments.
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42

Lyman, D. F., and B. Yedvobnick. "Drosophila Notch receptor activity suppresses Hairless function during adult external sensory organ development." Genetics 141, no. 4 (December 1, 1995): 1491–505. http://dx.doi.org/10.1093/genetics/141.4.1491.

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Abstract The neurogenic Notch locus of Drosophila encodes a receptor necessary for cell fate decisions within equivalence groups, such as proneural clusters. Specification of alternate fates within clusters results from inhibitory communication among cells having comparable neural fate potential. Genetically, Hairless (H) acts as an antagonist of most neurogenic genes and may insulate neural precursor cells from inhibition. H function is required for commitment to the bristle sensory organ precursor (SOP) cell fate and for daughter cell fates. Using Notch gain-of-function alleles and conditional expression of an activated Notch transgene, we show that enhanced signaling produces H-like loss-of-function phenotypes by suppressing bristle SOP cell specification or by causing an H-like transformation of sensillum daughter cell fates. Furthermore, adults carrying Notch gain of function and H alleles exhibit synergistic enhancement of mutant phenotypes. Over-expression of an H+ transgene product suppressed virtually all phenotypes generated by Notch gain-of-function genotypes. Phenotypes resulting from over-expression of the H+ transgene were blocked by the Notch gain-of-function products, indicating a balance between Notch and H activity. The results suggest that H insulates SOP cells from inhibition and indicate that H activity is suppressed by Notch signaling.
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43

Eisenmann, D. M., J. N. Maloof, J. S. Simske, C. Kenyon, and S. K. Kim. "The beta-catenin homolog BAR-1 and LET-60 Ras coordinately regulate the Hox gene lin-39 during Caenorhabditis elegans vulval development." Development 125, no. 18 (September 15, 1998): 3667–80. http://dx.doi.org/10.1242/dev.125.18.3667.

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In C. elegans, the epithelial Pn.p cells adopt either a vulval precursor cell fate or fuse with the surrounding hypodermis (the F fate). Our results suggest that a Wnt signal transduced through a pathway involving the beta-catenin homolog BAR-1 controls whether P3.p through P8.p adopt the vulval precursor cell fate. In bar-1 mutants, P3.p through P8.p can adopt F fates instead of vulval precursor cell fates. The Wnt/bar-1 signaling pathway acts by regulating the expression of the Hox gene lin-39, since bar-1 is required for LIN-39 expression and forced lin-39 expression rescues the bar-1 mutant phenotype. LIN-39 activity is also regulated by the anchor cell signal/let-23 receptor tyrosine kinase/let-60 Ras signaling pathway. Our genetic and molecular experiments show that the vulval precursor cells can integrate the input from the BAR-1 and LET-60 Ras signaling pathways by coordinately regulating activity of the common target LIN-39 Hox.
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44

Wai, P., B. Truong, and K. M. Bhat. "Cell division genes promote asymmetric interaction between Numb and Notch in the Drosophila CNS." Development 126, no. 12 (June 15, 1999): 2759–70. http://dx.doi.org/10.1242/dev.126.12.2759.

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Cell intrinsic and cell extrinsic factors mediate asymmetric cell divisions during neurogenesis in the Drosophila embryo. In the NB4-2->GMC-1->RP2/sib lineage, one of the well-studied neuronal lineages in the ventral nerve cord, the Notch (N) signaling interacts with the asymmetrically localized Numb (Nb) to specify sibling neuronal fates to daughter cells of GMC-1. In this current study, we have investigated asymmetric cell fate specifications by N and Nb in the context of cell cycle. We have used loss-of-function mutations in N and nb, cell division mutants cyclinA (cycA), regulator of cyclin A1 (rca1) and string/cdc25 phosphatase (stg), and the microtubule destabilizing agent, nocodazole, to investigate this issue. We report that the loss of cycA, rca1 or stg leads to a block in the division of GMC-1, however, this GMC-1 exclusively adopts an RP2 identity. While the loss of N leads to the specification of RP2 fates to both progeny of GMC-1 and loss of nb results in the specification of sib fates to these daughter cells, the GMC-1 in the double mutant between nb and cycA assumes a sib fate. These epistasis results indicate that both N and nb function downstream of cell division genes and that progression through cell cycle is required for the asymmetric localization of Nb. In the absence of entry to metaphase, the Nb protein prevents the N signaling from specifying sib fate to the RP2/sib precursor. These results are also consistent with our finding that the sib cell is specified as RP2 in N; nb double mutants. Finally, our results show that nocodazole-arrested GMC-1 in wild-type embryos randomly assumes either an RP2 fate or a sib fate. This suggests that microtubules are involved in mediating the antagonistic interaction between Nb and N during RP2 and sib fate specification.
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45

Nelson, B. H., and D. A. Weisblat. "Cytoplasmic and cortical determinants interact to specify ectoderm and mesoderm in the leech embryo." Development 115, no. 1 (May 1, 1992): 103–15. http://dx.doi.org/10.1242/dev.115.1.103.

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In leech embryos, segmental ectoderm and mesoderm are produced by a pair of sister cells located near the animal and vegetal poles, respectively. We have investigated the mechanism that localizes ectodermal and mesodermal fates along the animal-vegetal axis. The results of cleavage arrest and cell ablation experiments suggest that the full range of normal cell interactions are not required for this process. However, when the animal and vegetal hemispheres are separated by re-orientation of the first cleavage plane from meridional to equatorial, the ectodermal fate co-segregates with the animal hemisphere and the mesodermal fate with the vegetal hemisphere. Two pools of yolk-deficient cytoplasm, called teloplasm, are located at the animal and vegetal poles of the zygote, but separation of the animal and vegetal teloplasms is not sufficient for the segregation of ectodermal and mesodermal fates. Rather, complete segregation of fates requires an equatorial cleavage orientation that separates not only the two teloplasms, but also the animal and vegetal cortical regions. This, in conjunction with previous findings, indicates that ectodermal determinants are localized to the cell cortex in the animal hemisphere of the zygote. We propose that these determinants segregate to the ectodermal precursor and interact with factors in teloplasm to transform the fate of this cell from a mesodermal ground state to ectoderm.
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46

Petratou, Kleio, Samantha A. Spencer, Robert N. Kelsh, and James A. Lister. "The MITF paralog tfec is required in neural crest development for fate specification of the iridophore lineage from a multipotent pigment cell progenitor." PLOS ONE 16, no. 1 (January 13, 2021): e0244794. http://dx.doi.org/10.1371/journal.pone.0244794.

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Understanding how fate specification of distinct cell-types from multipotent progenitors occurs is a fundamental question in embryology. Neural crest stem cells (NCSCs) generate extraordinarily diverse derivatives, including multiple neural, skeletogenic and pigment cell fates. Key transcription factors and extracellular signals specifying NCSC lineages remain to be identified, and we have only a little idea of how and when they function together to control fate. Zebrafish have three neural crest-derived pigment cell types, black melanocytes, light-reflecting iridophores and yellow xanthophores, which offer a powerful model for studying the molecular and cellular mechanisms of fate segregation. Mitfa has been identified as the master regulator of melanocyte fate. Here, we show that an Mitf-related transcription factor, Tfec, functions as master regulator of the iridophore fate. Surprisingly, our phenotypic analysis of tfec mutants demonstrates that Tfec also functions in the initial specification of all three pigment cell-types, although the melanocyte and xanthophore lineages recover later. We show that Mitfa represses tfec expression, revealing a likely mechanism contributing to the decision between melanocyte and iridophore fate. Our data are consistent with the long-standing proposal of a tripotent progenitor restricted to pigment cell fates. Moreover, we investigate activation, maintenance and function of tfec in multipotent NCSCs, demonstrating for the first time its role in the gene regulatory network forming and maintaining early neural crest cells. In summary, we build on our previous work to characterise the gene regulatory network governing iridophore development, establishing Tfec as the master regulator driving iridophore specification from multipotent progenitors, while shedding light on possible cellular mechanisms of progressive fate restriction.
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47

Dichtel, Marie-Laure, Sophie Louvet-Vallée, Mark E. Viney, Marie-Anne Félix, and Paul W. Sternberg. "Control of Vulval Cell Division Number in the Nematode Oscheius/Dolichorhabditis sp. CEW1." Genetics 157, no. 1 (January 1, 2001): 183–97. http://dx.doi.org/10.1093/genetics/157.1.183.

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Abstract Spatial patterning of vulval precursor cell fates is achieved through a different two-stage induction mechanism in the nematode Oscheius/Dolichorhabditis sp. CEW1 compared with Caenorhabditis elegans. We therefore performed a genetic screen for vulva mutants in Oscheius sp. CEW1. Most mutants display phenotypes unknown in C. elegans. Here we present the largest mutant category, which affects division number of the vulva precursors P(4-8).p without changing their fate. Among these mutations, some reduce the number of divisions of P4.p and P8.p specifically. Two mutants omit the second cell cycle of all vulval lineages. A large subset of mutants undergo additional rounds of vulval divisions. We also found precocious and retarded heterochronic mutants. Whereas the C. elegans vulval lineage mutants can be interpreted as overall (homeotic) changes in precursor cell fates with concomitant cell cycle changes, the mutants described in Oscheius sp. CEW1 do not affect overall precursor fate and thereby dissociate the genetic mechanisms controlling vulval cell cycle and fate. Laser ablation experiments in these mutants reveal that the two first vulval divisions in Oscheius sp. CEW1 appear to be redundantly controlled by a gonad-independent mechanism and by a gonadal signal that operates partially independently of vulval fate induction.
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48

Olofin, Sam O., Tirimisiyu Folorunsho Oloko, Kazeem O. Isah, and Ahamuefula Ephraim Ogbonna. "Crude oil price–shale oil production nexus: a predictability analysis." International Journal of Energy Sector Management 14, no. 4 (January 16, 2020): 729–44. http://dx.doi.org/10.1108/ijesm-05-2019-0004.

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Purpose The purpose of this study is to investigate the predictability of crude oil price and shale oil production, in a bid to examine the possibility of bi-directional causality. Design/methodology/approach The study adopts a recently developed predictability model by Westerlund and Narayan (2015), which accounts for persistence, endogeneity and heteroscedasticity. It also accounts for structural breaks in the predictive models. Findings The empirical results show that only a unidirectional causal relationship from crude oil price to shale oil production exists. This happens as crude oil price appears to be a good predictor of shale oil production; however, shale oil production does not serve as a good predictor for crude oil price. Accounting for structural break was found to improve the predictability and forecast accuracy of the predictive model. Our result is robust to choice of crude oil price benchmarks (West Texas Intermediate, Brent, Dubai Fateh and Refiners’ Acquisition Cost) and their denominations (real or nominal). Research limitations/implications The result implies that crude oil price must be considered when predicting shale oil production. Meanwhile, the non-significance of shale of production in crude oil price predictive model provides information to potential analyst, researchers and countries predicting crude oil price that failure to account for the effect of shale oil production would not have significant impact on the forecast accuracy of their models. Originality/value The study contributes originally to the literature on crude oil price–shale oil production in four major ways. First, it applies a recently developed predictability method by Westerlund and Narayan (2015), which is more suitable for dealing with persistence, conditional heteroscedasticity and endogeneity in the predictors. Second, it investigates existence of reverse causality between crude oil price and shale oil production. Third, it examines the variation in the response and effect of four major crude oil price benchmarks. Fourth, it considers crude oil price in both real and nominal terms.
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Romano, Shannon, Odelya H. Kaufman, and Florence L. Marlow. "Loss of dmrt1 restores zebrafish female fates in the absence of cyp19a1a but not rbpms2a/b." Development 147, no. 18 (September 7, 2020): dev190942. http://dx.doi.org/10.1242/dev.190942.

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ABSTRACTSex determination and differentiation is a complex process regulated by multiple factors, including factors from the germline or surrounding somatic tissue. In zebrafish, sex-determination involves establishment of a bipotential ovary that undergoes sex-specific differentiation and maintenance to form the functional adult gonad. However, the relationships among these factors are not fully understood. Here, we identify potential Rbpms2 targets and apply genetic epistasis experiments to decipher the genetic hierarchy of regulators of sex-specific differentiation. We provide genetic evidence that the crucial female factor rbpms2 is epistatic to the male factor dmrt1 in terms of adult sex. Moreover, the role of Rbpms2 in promoting female fates extends beyond repression of Dmrt1, as Rbpms2 is essential for female differentiation even in the absence of Dmrt1. In contrast, female fates can be restored in mutants lacking both cyp19a1a and dmrt1, and prolonged in bmp15 mutants in the absence of dmrt1. Taken together, this work indicates that cyp19a1a-mediated suppression of dmrt1 establishes a bipotential ovary and initiates female fate acquisition. Then, after female fate specification, Cyp19a1a regulates subsequent oocyte maturation and sustains female fates independently of Dmrt1 repression.
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50

Morrow, Theresa, Mi-Ryoung Song, and Anirvan Ghosh. "Sequential specification of neurons and glia by developmentally regulated extracellular factors." Development 128, no. 18 (September 15, 2001): 3585–94. http://dx.doi.org/10.1242/dev.128.18.3585.

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Cortical progenitor cells give rise to neurons during embryonic development and to glia after birth. While lineage studies indicate that multipotent progenitor cells are capable of generating both neurons and glia, the role of extracellular signals in regulating the sequential differentiation of these cells is poorly understood. To investigate how factors in the developing cortex might influence cell fate, we developed a cortical slice overlay assay in which cortical progenitor cells are cultured over cortical slices from different developmental stages. We find that embryonic cortical progenitors cultured over embryonic cortical slices differentiate into neurons and those cultured over postnatal cortical slices differentiate into glia, suggesting that the fate of embryonic progenitors can be influenced by developmentally regulated signals. In contrast, postnatal progenitor cells differentiate into glial cells when cultured over either embryonic or postnatal cortical slices. Clonal analysis indicates that the postnatal cortex produces a diffusible factor that induces progenitor cells to adopt glial fates at the expense of neuronal fates. The effects of the postnatal cortical signals on glial cell differentiation are mimicked by FGF2 and CNTF, which induce glial fate specification and terminal glial differentiation respectively. These observations indicate that cell fate specification and terminal differentiation can be independently regulated and suggest that the sequential generation of neurons and glia in the cortex is regulated by a developmental increase in gliogenic signals.
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