Relevant bibliographies by topics / Fatty acid elongation

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers
  5. Reports

Academic literature on the topic 'Fatty acid elongation'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Fatty acid elongation"

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Zank, T. K., U. Zähringer, J. Lerchl та E. Heinz. "Cloning and functional expression of the first plant fatty acid elongase specific for Δ6-polyunsaturated fatty acids". Biochemical Society Transactions 28, № 6 (2000): 654–58. http://dx.doi.org/10.1042/bst0280654.

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In order to elucidate the biosynthesis of longchain polyunsaturated fatty acids (PUFAs) in plants we searched for a cDNA encoding a Δ6-specific PUFA elongase from Physcomitrella patens which is known to contain high proportions of arachidonic acid (20:4 Δ5,8,11,14). An EST clone from P. patens was identified by its low homology to the yeast gene ELO1, which is required for the elongation of medium-chain fatty acids. We functionally characterized this cDNA by heterologous expression in Saccharomyces cerevisiae grown in the presence of several fatty acids. Analysis of the fatty acid profile of t
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Das, T., J. M. Thurmond, E. Bobik, et al. "Polyunsaturated fatty acid-specific elongation enzymes." Biochemical Society Transactions 28, no. 6 (2000): 658–60. http://dx.doi.org/10.1042/bst0280658.

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We have isolated a novel gene (GLELO) from Mortierella alpina and its homologue (CEELO1) from Caenorhabditis elegans and demonstrate the involvement of their encoded proteins in the elongation of C18 polyunsaturated fatty acids.
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Torella, J. P., T. J. Ford, S. N. Kim, A. M. Chen, J. C. Way, and P. A. Silver. "Tailored fatty acid synthesis via dynamic control of fatty acid elongation." Proceedings of the National Academy of Sciences 110, no. 28 (2013): 11290–95. http://dx.doi.org/10.1073/pnas.1307129110.

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Christiansen, E. N., T. Rørtveit, K. R. Norum, and M. S. Thomassen. "Fatty-acid chain elongation in rat small intestine." Biochemical Journal 237, no. 1 (1986): 293–95. http://dx.doi.org/10.1042/bj2370293.

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Microsomal fractions from rat small intestine contain a fatty-acid chain-elongation activity. Cofactor requirements are similar to those of the liver microsomal system, but substrate specificity is different. The polyunsaturated arachidonic and timnodonic acids were elongated at very low rates. These results suggest that the relative contents of specific chain-elongation enzymes are different in liver and small intestine.
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Dyer, William E. "Inhibitors of Fatty Acid Synthesis and Elongation." Journal of Natural Resources and Life Sciences Education 37, no. 1 (2008): 132. http://dx.doi.org/10.2134/jnrlse2008.371132x.

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Tehlivets, Oksana, Kim Scheuringer, and Sepp D. Kohlwein. "Fatty acid synthesis and elongation in yeast." Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1771, no. 3 (2007): 255–70. http://dx.doi.org/10.1016/j.bbalip.2006.07.004.

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Matthes, Bernd, Jochen Schmalfuß, and Peter Böger. "Chloroacetamide Mode of Action, II: Inhibition of Very Long Chain Fatty Acid Synthesis in Higher Plants." Zeitschrift für Naturforschung C 53, no. 11-12 (1998): 1004–11. http://dx.doi.org/10.1515/znc-1998-11-1211.

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Abstract In short-term -experiments [14C]-labelled malonic acid, stearic acid and acetate have been incorporated into leaf fatty acids of seedlings of Cucumis sativus, Hordeum vulgare and Zea mays. The pattern of labelled fatty acids changed markedly by treatment with the chloroacetamide herbicides metazachlor, metolachlor or butachlor. During a 2-h incubation time, 1 μᴍ chloroacetamide specifically inhibited up to 100% the formation of the saturated very long chain fatty acids (V LCFAs) with a carbon number of 20, 22 and 24. In cucumber and barley a 50% inhibition of VLCFA formation is achiev
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Abulnaja, Khalid O., and John L. Harwood. "Effect of a Safener Towards Thiocarbamates on Plant Lipid Metabolism." Zeitschrift für Naturforschung C 46, no. 9-10 (1991): 931–33. http://dx.doi.org/10.1515/znc-1991-9-1035.

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Abstract It has been found that various thiocarbamate herbicides, known to alter surface wax and cutin synthesis, inhibit the elongation of fatty acids. We have proposed this as a mode of ac­tion of such compounds. Because it is believed that the sulphoxide metabolites of thiocarba­mates are the active intermediates, we have examined the action of 1-aminobenzotriazole (an inhibitor of sulphoxide formation) on the inhibition of very long-chain fatty acid biosynthesis. In all tissues tested, aminobenzotriazole was able to block the specific inhibitory effect of thio­carbamates on fatty acid elon
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Kohlwein, Sepp D., Sandra Eder, Chan-Seok Oh, et al. "Tsc13p Is Required for Fatty Acid Elongation and Localizes to a Novel Structure at the Nuclear-Vacuolar Interface inSaccharomyces cerevisiae." Molecular and Cellular Biology 21, no. 1 (2001): 109–25. http://dx.doi.org/10.1128/mcb.21.1.109-125.2001.

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ABSTRACT The TSC13/YDL015c gene was identified in a screen for suppressors of the calcium sensitivity of csg2Δ mutants that are defective in sphingolipid synthesis. The fatty acid moiety of sphingolipids in Saccharomyces cerevisiae is a very long chain fatty acid (VLCFA) that is synthesized by a microsomal enzyme system that lengthens the palmitate produced by cytosolic fatty acid synthase by two carbon units in each cycle of elongation. TheTSC13 gene encodes a protein required for elongation, possibly the enoyl reductase that catalyzes the last step in each cycle of elongation. The tsc13 muta
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Schneiter, Roger, Verena Tatzer, Gabriela Gogg, Erich Leitner та Sepp Dieter Kohlwein. "Elo1p-Dependent Carboxy-Terminal Elongation of C14:1Δ9 to C16:1Δ11 Fatty Acids inSaccharomyces cerevisiae". Journal of Bacteriology 182, № 13 (2000): 3655–60. http://dx.doi.org/10.1128/jb.182.13.3655-3660.2000.

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ABSTRACT Saccharomyces cerevisiae medium-chain acyl elongase (ELO1) mutants have previously been isolated in screens for fatty acid synthetase (FAS) mutants that fail to grow on myristic acid (C14:0)-supplemented media. Here we report that wild-type cells cultivated in myristoleic acid (C14:1Δ9)-supplemented media synthesized a novel unsaturated fatty acid that was identified as C16:1Δ11 fatty acid by gas chromatography-mass spectroscopy. Synthesis of C16:1Δ11 was dependent on a functional ELO1 gene, indicating that Elo1p catalyzes carboxy-terminal elongation of unsaturated fatty acids (α-elon
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Dissertations / Theses on the topic "Fatty acid elongation"

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Zadravec, Damir. "Metabolic Significance of Fatty Acid Elongation." Doctoral thesis, Stockholm : Department of Physiology, Stockholm University, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-34815.

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Diss. (sammanfattning) Stockholm : Stockholms universitet, 2010.<br>At the time of the doctoral defence, the following papers were unpublished and had status as follows: Paper 3: Manuscript. Paper 4: Manuscript. Paper 5: Submitted. Paper 6: Manuscript. Härtill 6 uppsatser.
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Brolinson, Annelie. "Regulation of Elovl and fatty acid metabolism." Doctoral thesis, Stockholm : Wenner-Gren Institute for Experimental Biology, Stockholm university : Stockholm University Library [distributör], 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-8469.

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Pujol, F. (François). "Experiments on fatty acids chain elongation and glycan flipping in the ER membrane." Doctoral thesis, University of Oulu, 2009. http://urn.fi/urn:isbn:9789514290695.

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Abstract Very long chain fatty acids (VLCFA) are essential molecules that take part in many different cellular processes such as membrane pore stabilization, membrane trafficking and signaling pathways. The fatty acid elongation pathway in yeast has been studied for about a decade. As part of our work on cellular VLCFA elongation, we identified and characterized the condensing enzyme as well as ketoacyl reductases of the elongation pathway in cotton. In order to identify the yeast 3-hydroxyacyl-CoA dehydratase, we introduced a redundancy in this function by engineering a chimera consisting
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Haslam, Tegan M. "Arabidopsis ECERIFERUM2-LIKE proteins are components of the fatty acid elongation machinery required for the production of cuticular waxes." Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/61330.

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Very-long-chain fatty acids (VLCFAs) are essential molecules produced by all plant cells, and are precursors of diverse primary and specialized metabolites. VLCFAs are elongated by a fatty acid elongation (FAE) complex of four core enzymes located on the endoplasmic reticulum, which sequentially adds two carbon units to a growing acyl-CoA chain. Identification and characterization of FAE enzymes in Arabidopsis thaliana has revealed that three of the four enzymes act as generalists, contributing to all metabolic pathways that require VLCFAs. A fourth component, the condensing enzyme, prov
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Gimple, Ryan Christopher. "Epigenetic Landscapes Identify Functional Therapeutic Vulnerabilities in Glioblastoma." Case Western Reserve University School of Graduate Studies / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=case1587732572817921.

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Segura, Julio Guerra. "Influência da relação 18:3n3/18:2n6 de rações exclusivamente vegetais sobre o metabolismo de ácidos graxos de juvenis de pacu (Piaractus mesopotamicus)." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/74/74131/tde-30112016-113845/.

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Novas alternativas de produção de ácidos graxos altamente insaturados n-3 (HUFA n-3) são procuradas mediante várias abordagens experimentais na área aquícola considerando que a oferta atual de óleos marinhos é limitada. Como os ácidos graxos das séries n-3 e n-6 são metabolizados mediante os mesmos processos enzimáticos, o aporte de ácidos graxos essenciais da dieta poderia influenciar nos níveis de alongamento e desaturação em função da disponibilidade relativa destes compostos. O objetivo deste trabalho foi determinar a influência de diferentes relações 18:3n3/18:2n6 (ALA/LA - ácido linolêni
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"Reductive Dechlorination Sustained by Microbial Chain Elongation." Master's thesis, 2019. http://hdl.handle.net/2286/R.I.53835.

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abstract: Trichloroethene (TCE) is a ubiquitous soil and groundwater contaminant. The most common bioremediation approach for TCE relies on the process of reductive dechlorination by Dehalococcoides mccartyi. D. mccartyi use TCE, dichloroethene, and vinyl chloride as electron acceptors and hydrogen as an electron donor. At contaminated sites, reductive dechlorination is typically promoted by adding a fermentable substrate, which is broken down to short chain fatty acids, simple alcohols, and hydrogen. This study explored microbial chain elongation (MCE), instead of fermentation, to promote TCE
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Scherson, Rosa Amelia. "Analysis of KCS2 : a gene encoding a new condensing enzyme for the elongation of very long chain fatty acids in Arabidopsis thaliana." Thesis, 2000. http://hdl.handle.net/2429/10954.

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Condensing enzymes for very long chain fatty acid (VLCFA) synthesis catalyze the first of a series of four reactions that elongate the growing acyl chain by two carbons at a time. It has been shown that the activity of the condensing enzyme determines the amount and acyl chain length of the VLCFAs produced by a fatty acid elongation system. My research project focused on the characterization of KCS2, a new putative condensing enzyme of Arabidopsis thaliana. Computer database analyses showed that the KCS2 gene is located directly upstream of the FAE1 gene, the first condensing enzyme for
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Book chapters on the topic "Fatty acid elongation"

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Han, Jixiang, Frank P. Wolter, Jan G. Jaworski, and Margrit Frentzen. "Brassica KCS is Capable of Elongating Polyunsaturated Fatty Acids." In Advanced Research on Plant Lipids. Springer Netherlands, 2003. http://dx.doi.org/10.1007/978-94-017-0159-4_11.

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Imai, Hiroyuki, Alenka Hlousek-Radojcic, Andrea Matthis, and Jan Jaworski. "Elongation System Involved in the Biosynthesis of very Long Chain Fatty Acids in Brassica Napus Seeds: Characterization and Solubilization." In Plant Lipid Metabolism. Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-015-8394-7_34.

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Bond, Laura M., Makoto Miyazaki, Lucas M. O’Neill, Fang Ding, and James M. Ntambi. "Fatty Acid Desaturation and Elongation in Mammals." In Biochemistry of Lipids, Lipoproteins and Membranes. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-444-63438-2.00006-7.

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O'Neill, Lucas M., Makoto Miyazaki, Laura M. Bond, et al. "Fatty acid desaturation and elongation in mammals." In Biochemistry of Lipids, Lipoproteins and Membranes. Elsevier, 2021. http://dx.doi.org/10.1016/b978-0-12-824048-9.00014-6.

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Miyazaki, Makoto, and James M. Ntambi. "Fatty acid desaturation and chain elongation in mammals." In Biochemistry of Lipids, Lipoproteins and Membranes. Elsevier, 2008. http://dx.doi.org/10.1016/b978-044453219-0.50009-x.

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BRENNER, RODOLFO R. "Factors Influencing Fatty Acid Chain Elongation and Desaturation." In Role of Fats in Human Nutrition. Elsevier, 1989. http://dx.doi.org/10.1016/b978-0-12-718051-9.50006-8.

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Cook, Harold W. "Fatty acid desaturation and chain elongation in eukaryotes." In Biochemistry of Lipids, Lipoproteins and Membranes. Elsevier, 1996. http://dx.doi.org/10.1016/s0167-7306(08)60512-8.

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Cook, Harold W., and Christopher R. McMaster. "Chapter 7 Fatty acid desaturation and chain elongation in eukaryotes." In Biochemistry of Lipids, Lipoproteins and Membranes, 4th edition. Elsevier, 2002. http://dx.doi.org/10.1016/s0167-7306(02)36009-5.

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Cook, Harold W. "Chapter 5 Fatty acid desaturation and chain elongation in eucaryotes." In New Comprehensive Biochemistry. Elsevier, 1991. http://dx.doi.org/10.1016/s0167-7306(08)60333-6.

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O-Thong, Sompong, Xinyu Zhu, Irini Angelidaki, Shicheng Zhang, and Gang Luo. "Medium chain fatty acids production by microbial chain elongation: Recent advances." In Advances in Bioenergy. Elsevier, 2020. http://dx.doi.org/10.1016/bs.aibe.2020.04.002.

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Conference papers on the topic "Fatty acid elongation"

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Al-Qeraiwi, Maha, Manar Al-Rashid, Nasser Rizk, Abdelrahman El Gamal, and Amena Fadl. "Hepatic Gene Expression Profile of Lipid Metabolism of Obese Mice after treatment with Anti-obesity Drug." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0214.

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Obesity is a global disorder with multifactorial causes. The liver plays a vital role in fat metabolism. Disorder of hepatic fat metabolism is associated with obesity and causes fatty liver. High fat diet intake (HFD) to mice causes the development of dietinduced obesity (DIO). The study aimed to detect the effects of anti-obesity drugs (sulforaphane; SFN and leptin) on hepatic gene expression of fat metabolism in mice that were fed HFD during an early time of DIO. Twenty wild types (WT) CD1 male mice aged ten weeks were fed a high fat diet. The mice were treated with vehicle; Veh (control gro
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Reports on the topic "Fatty acid elongation"

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Paul, Shilpi. Characterization of Enzymes Involved in Fatty Acid Elongation. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ad1014036.

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