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Journal articles on the topic 'Fatty hepatosis'

Author: Grafiati

Published: 3 June 2025

Last updated: 1 August 2025

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1

Abdiev, Ilkhom Allaerovich, Umid Madaminovich Bozorov, Xusnitdin Baymuratovich Xujanov, and Nilufar Iskandarova. "DEVELOPMENT OF FATTY HEPATOSIS IN PATIENTS WITH DIABETES MELLITUS." Multidisciplinary Journal of Science and Technology 4, no. 1 (2024): 218–21. https://doi.org/10.5281/zenodo.10565935.

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It was made an organized study of the functional condition of hepato-biliary system beside 200 patients with fatty hepatosis and fatty hepatosis with concomitant sugar diabetes. In verification of the diagnosis were used results of the biochemical blood`s study, ultrasonography study, computer and MR tomography. All patients were conducted with duodenal tubing with following biochemical bile study. Breach of the functional condition liver was revealled beside majority sick fatty hepatosis, moreover degree of the breaches becomes above under accompanying sugar diabetes. Unidirectional change in

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2

Gavrilova, Oksana A., Lyubov V. Rychkova, Marina A. Darenskaya, Lyudmila A. Grebenkina, Olga V. Kravtsova, and Larisa V. Natyaganova. "Change of Lipid Peroxidation System – Antioxidant Protection Parameters in Adolescents with Obesity and Fatty Hepatosis." Acta Biomedica Scientifica 4, no. 1 (2019): 9–13. http://dx.doi.org/10.29413/abs.2019-4.1.1.

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Background. Spread of childhood obesity is associated with social and economic factors of modern lifestyle that alter food preferences and lead to sedentary life. Nowadays fatty hepatosis is considered a hepatic manifestation of the metabolic syndrome, which is linked to the rising prevalence of obesity among the population. There is evidence of a correlation between metabolic disorders and oxidative stress reactions.Aims. To study characteristics of lipid peroxidation system and antioxidant defense processes in adolescents with fatty hepatosis.Materials and methods. We examined 15 adolescents

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3

MALYAVSKAYA, S. I., A. V. LEBEDEV, and G. N. KOSTROVA. "Atherogenic disorders in adolescents with ultrasound signs of fatty hepatosis and hyperuricemia." Practical medicine 21, no. 6 (2023): 22–26. http://dx.doi.org/10.32000/2072-1757-2023-6-22-26.

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The purpose — to study the features and relationship of blood uric acid and metabolic atherogenic disorders in adolescents with fatty hepatosis. Material and methods. The study of atherogenic disorders included the following groups: 1 — adolescents with fatty hepatosis and hyperuricemia (n = 44), 2 — adolescents with fatty hepatosis and normal blood uric acid levels (n = 76), 3 (comparison group) — adolescents without acute and chronic diseases (n = 220). The study results showed higher values of average body mass index, waist circumference, triglycerides, total lipid peroxidation, glucose, HO

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4

Burkov, P. V., P. N. Scherbakov, and M. B. Rebezov. "The use of the drug "Ovostim-c" in the prevention of hepatosis and retention of placenta in cows after calving." Agrarian science 1, no. 7-8 (2022): 44–48. http://dx.doi.org/10.32634/0869-8155-2022-361-7-8-44-48.

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Relevance. High milk productivity of cows after calving is the cause of liver damage in the form of hepatosis and premature retirement of animals. In such cases, pathoanatomical examination of the liver reveals simultaneously disorders in the form of protein and fatty dystrophies with subsequent destruction of cellsand circulatory disorders. Hepatoses can also cause such postpartum complications in cows as retention of placenta .Methods. For the prevention of hepatosis, the drug "Ovostim-ct" is proposed, which contains cytotoxic serums against the tissues of the liver, ovary, spleen and muscle

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Kovalyuk, Natalia V., Elena V. Kuzminova, Marina P. Semenenko, Andrey A. Abramov, and Ludmila I. Yakusheva. "The relationship between snp-polymorphisms of the leptin gene and the development of fatty liver disease in dairy cows." E3S Web of Conferences 254 (2021): 09019. http://dx.doi.org/10.1051/e3sconf/202125409019.

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This article shows the results of studies in the course of which in a comparative aspect the LEP polymorphism was studied in subpopulations of Holstein dairy cattle in cows with fatty hepatosis and in healthy animals. This is the first time such studies are being conducted. In this case, a hepothesis about the relationship of genetic markers, in particular the leptin gene, with the risk of developing and progression of fatty liver disease in a model of dairy cows when determining the frequency of occurrence of genotypes with LEP polymorphisms in groups of animals with hepatosis and healthy ani

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MALYAVSKAYA, S. I., A. V. LEBEDEV, G. N. KOSTROVA, V. A. FOKINA, and V. A. SEMENOV. "Metabolic atherogenic disorders in adolescents with fatty hepatosis." Practical medicine 19, no. 5 (2021): 63–66. http://dx.doi.org/10.32000/2072-1757-2021-5-63-66.

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To determine the features of disorders and the relationship of the blood lipid spectrum, indicators of peroxidation and insulin resistance in adolescents with fatty hepatosis, a single-stage study was conducted of a sample of 58 adolescents from Arkhangelsk aged 16–17 y. o. who have instrumental signs of fatty hepatosis according to ultrasound diagnostics. The comparison group consisted of 219 adolescents from Arkhangelsk who did not have acute and chronic diseases at the time of the examination. The results of the study showed higher average values of total lipid peroxidation, HOMA index, ins

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7

Burkov, P. V. "Use of Ovostim-CT in the prevention of hepatosis and retention of placenta in cows after calving." E3S Web of Conferences 282 (2021): 03014. http://dx.doi.org/10.1051/e3sconf/202128203014.

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High milk productivity of cows after calving is the cause of liver damage in the form of hepatosis and premature retirement of animals. In such cases, a pathological examination simultaneously reveals violations in the form of protein and fatty degenerations with the subsequent destruction of cells, as well as disturbed circulation in the liver. Also, hepatoses can cause such postpartum complications in cows as retention of placenta. For the prevention of hepatosis, the drug “Ovostim-ct” is proposed, which contains cytotoxic sera against the tissues of the liver, ovary, spleen and muscle. In o

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8

Illek, Josef, Stanislav Veselskyi, Andrii Pototskyi, Viktoriia Gryshchenko, and Yevdokiia Reshetnik. "Bilirubin derivatives in bile, blood, and liver of rats upon correction of experimental fatty hepatosis." Ukrainian journal of veterinary sciences 15, no. 2 (2024): 46–65. http://dx.doi.org/10.31548/veterinary2.2024.46.

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The relevance of this study lies in the lack of reliable information on the key aspects of the molecular mechanisms of fatty hepatosis, a common mammalian disease, and its dangerous complications, such as fibrosis, cirrhosis, and hepatocellular carcinoma. These circumstances substantially complicate the prompt diagnosis of this hepatopathology and reduce the effectiveness of treatment. The metabolism of the heme derivative bilirubin is unique and inherent in the liver, which undergoes transformation due to hepatocyte enzyme systems to form neutral compounds, such as glucurono-conjugates and su

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9

K. O. Gerasymenko. "Forensic medical diagnosis of alcoholic encephalopathy." Bukovinian Medical Herald 17, no. 3 (67) p.1 (2013): 40–41. http://dx.doi.org/10.24061/2413-0737.xvii.3.67.2013.123.

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10

Geller, L. I., L. N. Gladkikh, and M. V. Gryaznova. "Therapy of diabetics with fatty hepatosis." Problems of Endocrinology 39, no. 5 (1993): 20–22. http://dx.doi.org/10.14341/probl11935.

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A ten-day course of karsil (silimarin, legalon) or silibor therapy improved the absorption (as indicated by ueviridin test) and oxidative-antitoxic (as shown by antipyrin test) hepatocyte functions in patients with non-insulin-dependent diabetes mellitus with hepatosis. A similar ten-day course of Liv-52 did not change the studied liver parameters. lnductothermal exposure of the splenic area (a 20 min session daily for 5 days) improved the absorption and antitoxic functions of the liver in diabetics. A positive effect of splenic inductothermia persisted for at least two weeks. The peak values

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11

Zefirova, T. P., and N. Yu Chistyakova. "Hepatosis of pregnant women." Kazan medical journal 66, no. 4 (1985): 300–302. http://dx.doi.org/10.17816/kazmj61896.

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Acute fatty hepatosis of pregnant women is a poorly understood and rare liver disease that occurs in late pregnancy and is characterized by a severe course and serious complications for the mother and fetus. Maternal mortality in this case reaches 80-85%.

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12

Qizi, Urunova Iroda Isroil. "Study Of The Market Of Drugs Used In Hepatosis." American Journal of Medical Sciences and Pharmaceutical Research 03, no. 02 (2021): 45–49. http://dx.doi.org/10.37547/tajmspr/volume03issue02-06.

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This article reveals the need for study of the market of drugs used in hepatosis, it is rather difficult to substantiate and systematize the treatment of fatty hepatosis with such a variety of causes that cause it. therapy should be aimed at eliminating the causes, at stopping the syndromes of impaired digestion and absorption, at restoring the function of the liver and biliary system. this excludes the intake of certain drugs and alcohol abuse.

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13

Khlebus, N. K. "MARKERS OF METABOLIC DISORDERS IN THE BLOOD OF SOWS IN CASE OF HEPATODYSTROPHY." Vestnik of Ulyanovsk state agricultural academy 206 (March 25, 2022): 141–47. http://dx.doi.org/10.18286/1816-4501-2022-1-141-147.

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Liver diseases are widespread among pigs of different gender and age groups. Hepatodystrophy (hepatosis) is most often recorded among liver diseases. Various metabolic disorders develop in sows with hepatosis. Groups of sows of different ages (farrow number) with biochemical changes which are specific for hepatosis were formed in the conditions of the pig-breeding complex. In total, six groups of 5 sows in each were formed. The list of biochemical parameters allowed to assess the state of protein, lipid, carbohydrate, mineral and pigment metabolism, as well as activity of a number of enzymes.

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14

Gulyaev, D. K., S. S. Zykova, V. D. Belonogova, D. O. Semakin, and N. A. Buzmakova. "Hepatoprotective Activity of Pine cones Extract." Drug development & registration 12, no. 4 (2023): 128–33. http://dx.doi.org/10.33380/2305-2066-2023-12-4(1)-1613.

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Introduction. Fatty hepatosis is a widespread metabolic disease. There is an annual increase in cases of detection of fatty hepatosis both in Russia and around the world. An urgent task is to search for new medicines for the treatment and prevention of the development of fatty hepatosis.Aim. Investigation of the composition of procyanidins and the biological activity of pine cones extract on a model of fatty hepatosis in vivo.Materials and methods. To obtain the extract, cones of pine harvested on the territory of the Perm Region in December were used. The extract was obtained by processing ra

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15

Myazin, R. G., G. L. Snigur, D. N. Emel'yanov, and M. V. Chernyshova. "Pharmacological Correction of Experimental Acute Toxic Hepatitis." Journal of Anatomy and Histopathology 8, no. 1 (2019): 49–54. http://dx.doi.org/10.18499/2225-7357-2019-8-1-49-54.

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The aim of study was to develop new methods of treatment of acute toxic hepatitis. To achieve this objective, the authors investigated dynamics of pathological changes in the hepatic tissue under acute intoxication followed by the pharmacological correction with sodium hypochlorite.Material and methods. The study included 45 male rats that were subjected to the experimental simulation of acute toxic hepatosis. Group 1 included intact animals; group 2 included animals that were intragastrically administered allyl alcohol resulting in acute toxic hepatosis; group 3 included rats with acute toxic

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16

Rashidova, Khurshida A. "Ultrasonic elastographic and morphological features of fatty hepatosis." Digital Diagnostics 4, no. 1S (2023): 111–12. http://dx.doi.org/10.17816/dd430362.

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BACKGROUND: Non-alcoholic fatty liver disease is a common chronic liver condition characterized by pathological accumulation of fatty droplets, which is not associated with alcohol consumption. The main reason in the development of complications and adverse outcomes of the disease is fibrotic changes in the liver, leading to cirrhosis. AIM: To determ the informative value of two-dimensional shear wave elastography in hepatosis by a comparative analysis of morphological and ultrasound elastometric findings. METHODS: The study included 40 patients aged 3560 years. The control group c

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17

Veselskyi, Stanislav, Andrii Pototskyi, Viktor Tomchuk, Viktoriia Gryshchenko, and Yevdokiia Reshetnik. "Phospholipid composition of bile and blood in rats under correction of experimental fatty hepatosis." Ukrainian journal of veterinary sciences 14, no. 3 (2023): 25–45. http://dx.doi.org/10.31548/veterinary3.2023.25.

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To date, the aetiology and molecular mechanisms of the development of fatty hepatosis, which is quite common in mammals, have not yet been sufficiently explained. This pathology requires detailed study not only because of functional disorders of the liver and biliary system, but also because of the high probability of dangerous complications – fibrosis, cirrhosis, or hepatocellular carcinoma. The purpose of this study was to determine marker changes in the phospholipid composition of bile and blood in rats with experimental fatty hepatosis and with the use of corrective therapy. Hepatopatholog

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18

Matkevich, E. I., A. N. Bashkov, E. A. Ionova, et al. "Modern Possibilities of Imaging Diagnosis Methods in Assessing the Severity of Fatty Hepatosis in Non-Alcoholic Fatty Liver Disease (Clinical Case)." MEDICAL RADIOLOGY AND RADIATION SAFETY 68, no. 6 (2023): 73–79. http://dx.doi.org/10.33266/1024-6177-2023-68-6-73-79.

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Purpose: To estimate the potential of imaging methods in the diagnosis of non-alcoholic fatty liver disease (NAFLD) based on the example of a clinical case. Material and methods: A 42 years-old man with suspected of NAFLD, by the clinical and laboratory tests results, underwent a quantitative assessment of fatty hepatosis using radiodiagnosis imaging methods. We used US “liver protocol” with attenuation imaging technique (ATI), shear wave elastography (SWE), shear wave dispersion imaging (SWD), computed tomography (CT) with quantitative and qualitative assessment using the liver-spleen index (

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19

Petrouski, S. U., A. I. Bolshakova, and A. I. Zhukov. "SOWS’ HEPATOPATHIES: MACRO- AND MICROSCOPIC CHANGES IN THE LIVER AND SOME INDICATORS OF PRODUCTIVITY." Transactions of the educational establishment “Vitebsk the Order of “the Badge of Honor” State Academy of Veterinary Medicine 59, no. 4 (2023): 35–42. http://dx.doi.org/10.52368/2078-0109-2023-59-4-35-42.

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During post-mortem examination sows’ liver, hepatopathy has been identified: acute hepatitis, chronic hepatitis and cirrhosis. Histological studies in liver tissues in all hepatopathies have been revealed granular, fatty, vacuolar degeneration, the chronic hepatosis and the development of liver cirrhosis - changes characteristic of interstitial hepatitis. The offspring of sows with chronic hepatosis and transition of interstitial hepatitis to liver cirrhosis, were revealed increasing in the number of low-tech piglets and their low live weight were found. Piglets raised under sows with hepatopa

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20

Ignatieva, D. P., D. Sh Enaleeva, and Sh A. Mukhametzyanov. "Childbirth after acute fatty hepatosis of pregnant women." Kazan medical journal 79, no. 3 (1998): 211. http://dx.doi.org/10.17816/kazmj64061.

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Acute fatty hepatosis (AFS) in pregnant women is a rare but formidable complication of pregnancy. Mortality in this pathology reaches 60-100%, but significantly decreases in the case of delivery in the pre-icterus period. We did not find in the available literature a description of childbirth after suffering from OZHH, in this regard, we present our own observation.

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21

Kurdekо, Alexander P., Natalia K. Khlebus та Elena I. Bоlshakоva. "STATUS ОF ОFFSPRING AND PIGLET GRОWTH DURING HEPATОPATHY ОF SОWS". Bulletin Samara State Agricultural Academy 7, № 2 (2022): 54–60. https://doi.org/10.55170/19973225_2022_7_2_54.

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The research purpose is to substantiate the implementation of preventive, including pharmacological measures against hepatosis (hepatopathy) of sows to increase their performance rate. Within the conditions of a pig breeding complex, the study of indicators characterizing the offspring of sows after farrowing was carried out. The group of animals was formed containing pregnant sows (90 days of pregnancy) with a different number of farrowings (from one to four or more).The indicators of a piglet growth during the milking period of a sow after lactation were studied (the group was formed on the

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22

Gryshchenko, V., S. Sуsoliatin, and S. Midyk. "Fatty acids of lipids of blood serum and liver of rats with tetracyclin-induced hepatosis and at correction." Regulatory Mechanisms in Biosystems 10, no. 4 (2019): 520–25. http://dx.doi.org/10.15421/021976.

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Irrational pharmacotherapy with tetracyclines can cause mitochondrial cytopathies of liver cells and the development of toxic dystrophy. The issue of violation of the qualitative and quantitative composition of fatty acids and their functional role in the development of liver dystrophy has not been studied enough. Therefore, the aim of the work was to determine the features of changes in the fatty acid composition of blood serum and liver lipids in rats with tetracycline-induced hepatosis and the corrective efficacy of the phospholipid-acceptable dietary supplement “FLP-MD”. It was experimenta

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Popova, O. S., V. S. Ponamarev, A. V. Kostrova, and L. A. Agafonova. "Elimination of 1,3,7-trimethylxanthine in laboratory animals during the induction of fatty hepatosis." International Journal of Veterinary Medicine, no. 4 (December 12, 2023): 179–85. http://dx.doi.org/10.52419/issn2072-2419.2023.4.179.

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Liver pathologies play a significant role in changing the metabolism and clearance of a number of pharmacologically active substances, including 1,3,7-trimethylxanthine, which is explained by their influence on enzyme systems that regulate the biotransformation of exogenous biologically active substances. Currently, changes in caffeine clearance are being actively studied in various hepatobiliary disorders, especially those that are chronic, since it is precisely such pathologies, according to a number of researchers, that are characterized by the most predictable and stable change in the trim

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24

Voronov, D. V., M. G. Minina, A. K. Chomaev, I. M. Iljinsky, and O. M. Tsirulnikova. "Liver steatosis in brain death donors." Russian Journal of Transplantology and Artificial Organs 23, no. 1 (2021): 8–14. http://dx.doi.org/10.15825/1995-1191-2021-1-8-14.

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Aim. To study the frequency of fatty hepatosis in liver biopsies of consecutive brain death donors before cold preservation. Materials and methods. Liver biopsies (before cold preservation) of 300 consecutive donors with brain death were studied. Histological preparations were stained with hematoxylin and eosin, and tricolor Masson staining was performed. Results. The frequency of different degrees of fat hepatosis in men and women did not differ significantly (>0.05). Fat dystrophy of hepatocytes was absent in more than half of the cases (n = 182; 60.7%). A slight degree of fatty degenerat

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Olesova, L. D., A. P. Chevychelov, P. I. Sobakin, et al. "The state of the adaptive potential of the working population in the zone of increased radiation exposure." YAKUT MEDICAL JOURNAL 83, no. 3 (2023): 51–57. https://doi.org/10.25789/ymj.2023.83.13.

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A radiological and medical-biological study of the population of Aldan and Tommot of the Aldan region of South Yakutia, located in the zone of increased natural radiation, was carried out. The annual individual effective exposure dose to the population turned out to be 2 times higher in the city of Aldan (6.22 mSv). The contribution of radon and its decay products in the city of Aldan was 59.5%, in the city of Tommot - 48.3%. Assessment of the adaptive potential (AP) of the circulatory system of the population showed a high percentage of the occurrence of functional stress of adaptation mechan

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Sirchak, E. S., V. I. Griga, Yo I. Pichkar, and N. Yu Kurchak. "Disbiotic changes in patients with non-alcoholic fatty liver disease." Medical alphabet 4, no. 38 (2020): 44–47. http://dx.doi.org/10.33667/2078-5631-2019-4-38(413)-44-47.

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The results of study at 96 patients with non-alcoholic fatty liver disease are presented. A high incidence of intestinal microbiome disorders was observed in the examined patients, especially at the stage of non-alcoholic steatohepatitis. The relationship between the persistence of impaired lipid metabolism and the degree of dysbiosis of the colon, namely between grade II dysbiosis and the level of total cholesterol in patients with non-alcoholic fatty hepatosis (r = 0.77; p < 0.01), and grade III dysbiosis and total cholesterol, triglycerides in patients with non-alcoholic fatty steatohepa

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Smolentsev, Sergey, Maria Onuchina, Zhanna Nikolaeva, et al. "Hepatoses in highly productive cows, their treatment and prevention." BIO Web of Conferences 149 (2024): 01015. http://dx.doi.org/10.1051/bioconf/202414901015.

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Ketone bodies in the urine of first-born heifers on the first day after calving constitute an indicator within the normal range, but by the 30th day after calving in sick animals, the reaction to ketone bodies is 8 times higher than normal. All changes indicate violations of protein and fat metabolism, as well as changes in the acid-base balance in the animal’s body, which is associated with impaired liver function and damage to this organ. In order to find the most effective method of pharmacoprophylaxis and pharmacotherapy of hepatoses and fatty liver dystrophy in the first heifers, the drug

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Fedulenkova, Yuliia Ya, Mykhailo S. Myroshnychenko, Olha M. Astapieva, Aleksandr A. Fatieiev, Kristina Od Akritova, and Dmytro V. Molodan. "CHARACTERISTICS OF AUTOPSY MATERIAL IN CASES OF CHRONIC DIFFUSE PATHOLOGY OF THE LIVER PARENCHYMA DIAGNOSED DURING PATIENT’S LIFETIME USING THE ULTRASOUND METHOD." Wiadomości Lekarskie 73, no. 9 (2020): 1995–99. http://dx.doi.org/10.36740/wlek202009218.

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The aim: Of the study is to analyze autopsy cases where chronic diffuse pathology of the liver parenchyma was diagnosed during patient’s lifetime using the ultrasound method. Material and methods: In this study archival material (autopsy protocols and microspecimens of these cases) of the pathological anatomy department of the Communal Nonprofit Enterprise «Regional Clinical Hospital» (Kharkiv) was used for the period from 2012 to 2018. The cases diagnosed with a chronic diffuse pathology of the liver parenchyma according to ultrasound data were selected among all cases. Microspecimens stained

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Klimova, E. M., Yu V. Kalashnikova, O. S. Merezhko, and T. I. Kordon. "INDIVIDUAL CORRECTION OF THE TREATMENT OF PATIENTS WITH HEPATOSPLENOMEGALY SYNDROME, TAKING INTO ACCOUNT THE PARAMETERS OF LIPID AND PROTEIN METABOLISM." Kharkiv Surgical School, no. 5-6 (December 14, 2020): 14–21. http://dx.doi.org/10.37699/2308-7005.5-6.2020.03.

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Summary. Purpose: to identify the features of lipid metabolism in patients with hepatosplenomegaly syndrome (HSS) of various origins to develop an individualized approach to the treatment of patients with this pathology. Materials and methods: blood serum of 73 patients with HSS on the background of liver cirrhosis complicated by portal hypertension, divided into 3 groups 1) with the etiological factor of hepatitis viruses HCV / HBV, 2) with autoimmune hepatitis with the etiological factor of the herpes group viruses CMV / VEB, 3) against the background of liver hepatosis and fermentopat

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Moiseeva, Karina, Polina Anipchenko, Svetlana Vasil’eva, et al. "PSVI-23 Dynamics of cholesterol and triglycerides in the serum of cows with liver lipidosis." Journal of Animal Science 97, Supplement_3 (2019): 208. http://dx.doi.org/10.1093/jas/skz258.427.

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Abstract Cows that received an over-calorie diet in the final phase of lactation are prone to liver lipidosis. The task of our research is to study the dynamics of cholesterol and triglycerides in cows with fatty hepatosis during the transit period. A group of 20 dry cows was formed. In the blood serum of cows, the concentration of cholesterol and triglycerides was studied twice before calving (15–20 days and 5–10 days) and twice after calving (5–10 days and 20–25 days). After research was formed two groups. The first group included 8 cows, which were killed 7–43 days after calving. They had s

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Orlova, S. V., A. N. Vodolazkaya, O. I. Tarasova, et al. "Phytonutrients in complex diet therapy for alcoholic liver disease and non-alcoholic fatty liver disease." Medical alphabet, no. 16 (September 5, 2024): 13–18. http://dx.doi.org/10.33667/2078-5631-2024-16-13-18.

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Alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD) are serious health problems with different epidemiological profiles. The long-term goal of treating chronic hepatosis is to prevent the progression of cirrhosis and/or liver cancer and prolong survival and patient’s quality of life. Herbal supplements containing medicinal plants, such as milk thistle, triphala, ginger and plants of the genus Phyllanthus, have great potential in optimizing the therapeutic effect in such patients.

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Maksimenko, Valery B., Luka A. Gromakov, and Svetlana E. Sinyutina. "PHARMACOEPIDEMIOLOGICAL STUDY OF THE EFFECTIVENESS OF HYPERGLYCEMIA CORRECTION AMONG PATIENTS WITH TYPE 2 DIABETES MELLITUS WITH LIVER LESIONS WITH DIABETES LOWERING THERAPY AND ESSENTIAL PHOSPHOLIPID DRUGS." Medicine and Physical Education: Science and Practice, no. 8 (2020): 28–40. http://dx.doi.org/10.20310/2658-7688-2020-2-4(8)-28-40.

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The aim of the study is to study the possibility of improving the effectiveness of hyperglycemia treatment among patients with type 2 diabetes mellitus by correcting the structural-functional state of the liver using essential phospholipid preparations. Materials and methods. The cohort retrospective study examined the medical histories of 1050 patients with type 2 diabetes mellitus, among whom 205 had liver complications. Diagnosis of steatohepatitis among patients with type 2 diabetes mellitus was verified based on increased activity of hepatic transaminases and serum bilirubin concentration

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Dergachova, D. I., O. I. Klein, A. A. Marinichev, et al. "Hepatoprotective effect of polyphenols in rats with experimental thioacetamide-induced toxic liver pathology." Bulletin of Russian State Medical University, no. 2019;6 (November 27, 2019): 70–76. http://dx.doi.org/10.24075/brsmu.2019.075.

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Non-alcoholic fatty liver disease is associated with a number of disorders (diabetes, obesity, cardiovascular diseases), and can also be induced by drugs or toxic compounds. Recently the important branch of medicine is the search for effective means of prevention and treatment of fatty hepatosis. Our work was aimed to study the effect of some biologically active natural polyphenols (resveratrol and pinosylvin stilbenes as well as dihydromyricetin dihydroflavonol) on the function and histologic features of the liver. In the experimental model of thioacetamide-induced toxic hepaptitis, the male

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Terekhova, O., and O. Uzakov. "Correction of Metabolic Disorders in Diabetic Nephropathy in Children and Adolescents." Bulletin of Science and Practice 6, no. 7 (2020): 127–32. http://dx.doi.org/10.33619/2414-2948/56/14.

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The article presents data on the use of the drug ursodeoxycholic acid (Ursosan) for hepatomegaly and fatty hepatosis in children with diabetic nephropathy. 40 children were examined. Material treated by variational statistics Statistica for Windows v. 6.0. Use of preparations of ursodeoxycholic acid in addition to the basic treatment results in a significant improvement of clinical symptoms and lipid metabolism in children, as well as a favorable course of the main disease. It was noted positive clinical dynamics when using this drug.

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Terekhova, O., and O. Uzakov. "Correction of Metabolic Disorders in Diabetic Nephropathy in Children and Adolescents." Bulletin of Science and Practice 6, no. 7 (2020): 127–32. https://doi.org/10.33619/2414-2948/56/14.

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The article presents data on the use of the drug ursodeoxycholic acid (Ursosan) for hepatomegaly and fatty hepatosis in children with diabetic nephropathy. 40 children were examined. Material treated by variational statistics Statistica for Windows v. 6.0. Use of preparations of ursodeoxycholic acid in addition to the basic treatment results in a significant improvement of clinical symptoms and lipid metabolism in children, as well as a favorable course of the main disease. It was noted positive clinical dynamics when using this drug.

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Sagitova, G. R., N. Yu Otto, M. Ya Ledyaev, et al. "DYNAMICS OF CHRONIC COMPLICATIONS OF TYPE 1 DIABETES IN CHILDREN AND ADOLESCENTS (OVER 20 YEARS)." Journal of Volgograd State Medical University 74, no. 2 (2020): 19–21. http://dx.doi.org/10.19163/1994-9480-2020-2(74)-19-21.

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During last decade the percent of complications of 1 type Diabetes mellitus in children decreased by 12 %, the structure of complications changed, but delay in growth and sexual development as well as fatty liver hepatosis occur in 25 % of cases. Decompensation of diabetes occurs more often in children between the ages of 11 to 16. The higher the level of HbA1c, the more complications occur. In patients with diabetes lasting 5 years or more the dose of insulin is more than 1 units/kg/day.

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Mikhailova, N. V., and I. L. Petrunko. "COMPLIANCE MONITORING IN PATIENTS WITH FATTY HEPATOSIS AT A RURAL THERAPEUTIC SITE." Transbaikalian Medical Bulletin, no. 1 (2021): 22–31. http://dx.doi.org/10.52485/19986173_2021_1_22.

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Grin, Vladimir A., Elena V. Kuzminova, Andrey A. Abramov, and Marina P. Semenenko. "Intensity of free radical oxidation of lipids at fatty hepatosis of cows." Veterinaria Kubani, no. 5 (October 28, 2019): 10–11. http://dx.doi.org/10.33861/2071-8020-2019-5-10-11.

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Spiridenko, G. Y., Y. A. Petrov, V. V. Chernavskiy, and N. V. Palieva. "ACUTE FATTY HEPATOSIS OF PREGNANT WOMEN: CLINICAL MANIFESTATIONS, EARLY DIAGNOSIS AND TREATMENT." Современные проблемы науки и образования (Modern Problems of Science and Education), no. 2 2022 (2022): 141. http://dx.doi.org/10.17513/spno.31656.

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Popova, O. S. "DIAGNOSTICS OF LIVER DISEASES IN CATTLE USING CAFFEINE CLEARANCE, WITH FATTY HEPATOSIS AS AN EXAMPLE." International Journal of Veterinary Medicine, no. 4 (January 16, 2025): 200–204. https://doi.org/10.52419/issn2072-2419.2024.4.200.

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Hepatic elimination is a function of interactions between various processes, such as sinusoidal absorption, intracellular metabolism, canalicular (biliary) secretion and sinusoidal outflow. The aim of our study was to investigate the relationship between the clinical condition of cattle with a confirmed diagnosis of fatty hepatosis and the metabolism of sodium caffeine benzoate. The studies were conducted on a farm in the Pskov region; the object of the study was Holsteinized cows, which underwent a medical examination, according to the results of which animals with fatty hepatosis were select

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Kurmaev, D. P., S. V. Bulgakova, E. V. Treneva, N. A. Pervyshin, L. A. Sharonova, and Yu A. Dolgikh. "Malnutrition, dysfunction of the gastrointestinal tract and sarcopenia - features of combined pathology." Experimental and Clinical Gastroenterology, no. 2 (March 26, 2024): 111–19. http://dx.doi.org/10.31146/1682-8658-ecg-222-2-111-119.

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One of the risk factors for the development of sarcopenia is malnutrition. Impairment of the energy value of the diet, the balance of proteins, fats and carbohydrates, a decrease in the protein-amino acid component of the nutritional diet - all this can lead to the development of sarcopenia. The intestinal microflora plays an important role in the process of growth and development of muscle tissue, in preventing its degradation with age. Fatty hepatosis and cirrhosis of the liver can also cause the development of sarcopenia. The problem is urgent and modern, and needs to be studied, which is w

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Gopchuk, E. N. "Medicated liver damage during pregnancy." HEALTH OF WOMAN, no. 9(145) (November 30, 2019): 43–49. http://dx.doi.org/10.15574/hw.2019.145.43.

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The significant frequency of drug-related liver damage during pregnancy, the lack of unified approaches to forecasting issues, the standards for diagnosis and drug correction, as well as the underestimation of the risk of disease for pregnancy outcomes characterize this problem as highly relevant and significant for modern obstetrics. Any drugs in a pregnant woman can cause drug hepatitis, so all of them should be prescribed to pregnant women only for strict clinical indications. In this case, one should take into account the genetic predisposition, history and risk factors for the development

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Pavlovskyi, S. A. "Efficiency of treatment of patients with non-alcoholic steatohepatitis combined with diabetes mellitus type 2 using the s-adenosylmethionin." Reports of Vinnytsia National Medical University 22, no. 1 (2018): 198–202. http://dx.doi.org/10.31393/reports-vnmedical-2018-22(1)-38.

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Non-alcoholic fatty liver disease is an important cause of chronic liver damage in many countries and is growing rapidly in both adults and children due to obesity and diabetes type 2. Aim — investigate the effectiveness of complex treatment of patients for the course of NASH using S-adenosylmethionin on the background of basic therapy. The study included 25 patients with non-alcoholic steatohepatitis against type 2 diabetes, age on average (58.69±1.25) years. The control group comprised 15 healthy individuals. In order to identify the diagnosis, data from clinical and laboratory, biochemical

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SOROKINA, TATIANA V., VALENTINA V. DAVYDOVA, NATALIA Yu KOLESNIK, et al. "APPLICATION OF ORGANIC COMPOUNDS IN THERAPEUTIC PRACTICE FOR LIVER FUNCTION DISTURBANCES." Bulletin of Contemporary Clinical Medicine 15, no. 2 (2022): 60–66. http://dx.doi.org/10.20969/vskm.2022.15(2).60-66.

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Introduction. The nonspecificity of the clinical manifestations of the initial stage of non-alcoholic fatty liver disease (NAFLD) - the stage of steatosis, is the reason for the untimely correction and progression of this disease. Aim. The aim of the study was to conduct a randomized open comparative study to determine the effectiveness of the use of the food supplement FanDetox as a source of organic compounds in liver function disorders. Material and methods. This study was a single-center randomized open one and included the study of the possibility of using the herbal product FanDetox in t

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Yuldasheva, D.X. Muzaffarova N.S. "ASSESSMENT OF THE DEVELOPMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE BY CLINICAL AND LABORATORY MARKERS." INTERNATIONAL BULLETIN OF MEDICAL SCIENCES AND CLINICAL RESEARCH 3, no. 5 (2023): 57–60. https://doi.org/10.5281/zenodo.7912658.

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Currently, non-alcoholic fatty liver disease (NAFLD) is one of the most common diseases in hepatology, leading to a deterioration in the quality of life, disability and death. The overall prevalence of NAFLD in the population ranges from 10 to 40% [1,3,5,6,7]. In the normal course of NAFLD, 12-40% of patients with hepatosis develop non-alcoholic steatohepatitis after 8-13 years. Of these, 15% of patients develop liver cirrhosis and liver failure. Of 7% of patients with liver cirrhosis, hepatocellular carcinoma develops within 10 years [2,3,5]. The heterogeneity of NAFLD leads to the absence of

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Нечипуренко, О. О., Д. В. Древаль, Д. Д. Провозін, and І. О. Собко. "ADENOVIRUS INFECTION AS ONE OF POSSIBLE CAUSES OF FATTY HEPATOSIS IN ONE DAY–OLD CHICKENS." Microbiology&Biotechnology, no. 4(36) (December 27, 2016): 86–95. http://dx.doi.org/10.18524/2307-4663.2016.4(36).86787.

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Toktogulova, Nurgul Asylbekovna, Aisuluu Asanovna Sydykbekova, and Umidzhon Abdikhaparovich Satarov. "The prevalence of ultrasound signs of fatty hepatosis and comorbidities in hospital patients in Kyrgyzstan." Scientific and practical journal "Healthcare of Kyrgyzstan", no. 4 (2022): 68–74. http://dx.doi.org/10.51350/zdravkg2022.4.10.9.68.

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Gordienko, A. V., I. I. Zhirkov, and D. Yu Serdyukov. "Lipid status and vascular bloodstream of servicemen with initial liver fibrosis." Bulletin of the Russian Military Medical Academy 20, no. 1 (2018): 98–101. http://dx.doi.org/10.17816/brmma12232.

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Frequency of violations of nutritional status, lipid metabolism, cardiovascular status and large vessels endothelium changes in servicemen with fatty liver dystrophy and early fibrosis are assessed. It is revealed that the prevalence of hepatic pathology with dysmetabolic aetiology in this category has vary from 41 to 67%, increasing in combination with subclinical atherosclerosis. According to the results of the study, it is found out that the fibrotic changes in the liver of servicemen associated with a higher frequency of abdominal obesity (higher body mass index and waist circumference), d

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Druzhinin, Valentin N., Vadim G. Suvorov, Nikolay V. Druzhinin, Aleksandr N. Cherniyi, and Sergey N. Troynyakov. "X-ray computer densitometry in the diagnosis of fat hepatosis." Russian Journal of Occupational Health and Industrial Ecology 60, no. 10 (2020): 681–86. http://dx.doi.org/10.31089/1026-9428-2020-60-10-681-686.

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Currently, the problem of reducing the risk of developing fat liver hepatosis from exposure to household and industrial toxicants among the working-age population continues to be an important medical and social problem, since not timely diagnosis of the disease can lead to its progressive course with the development of inflammatory changes, necrosis and liver fibrosis up to cirrhosis and hepatocellular cancer. In this regard, the search for methods and techniques that optimize the diagnosis of fat hepatosis is relevant. Modern methods of radiation diagnostics of liver density characteristics c

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Sulaeman, Agus, A. Rifai Amiruddin, and Gatot Susilo Lawrence. "Metabolic Syndrome (MetS) and Nonalcoholic Steatohepatitis (NASH): Study of biochemical markers Free Fatty Acid (FFA), Total Antioxidant Status (TAOS), Adiponectin, Transforming Growth Factor (TGF-beta1), in occurence of NASH." Indonesian Biomedical Journal 1, no. 1 (2009): 40. http://dx.doi.org/10.18585/inabj.v1i1.81.

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BACKGROUND: The prevalence of metabolic syndrome (MetS) in USA and Makassar are 22% and 23.7%. The prevalence of Non Alcoholic Steatosis Hepatosis (NASH) in MetS has not been reported. Study in Non-alcoholic Fatty Liver Disease (NAFLD) is 25–90 % in obesity patients. In NASH, there is accumulation of lipid in hepatocyte (raised free fatty acid level), raised stress oxidative (decreased total antioxidant status), raised of inflammation process (decreased adiponectin) and hepatic fibrotic process (raised TGF β1). The aim of this study is to investigate the correlation of free fatty acid, total a

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