Academic literature on the topic 'Fatty Liver – Hong Kong'

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Journal articles on the topic "Fatty Liver – Hong Kong"

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Wong, V. W. S., H. L. Y. Chan, A. Y. Hui, K. F. Chan, C. T. Liew, F. K. L. Chan, and J. J. Y. Sung. "Clinical and histological features of non-alcoholic fatty liver disease in Hong Kong Chinese." Alimentary Pharmacology & Therapeutics 20, no. 1 (June 14, 2004): 45–49. http://dx.doi.org/10.1111/j.1365-2036.2004.02012.x.

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Fung, James, Cheuk-Kwong Lee, Monica Chan, Wai-Kay Seto, Ching-Lung Lai, and Man-Fung Yuen. "High prevalence of non-alcoholic fatty liver disease in the Chinese - results from the Hong Kong liver health census." Liver International 35, no. 2 (July 7, 2014): 542–49. http://dx.doi.org/10.1111/liv.12619.

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Leung, Chi Man, Lawrence Siu Wing Lai, Wing Hang Wong, Kam Hoi Chan, Yiu Wing Luk, Jak Yiu Lai, Yat Wah Yeung, and Wai Mo Hui. "Non-alcoholic fatty liver disease: An expanding problem with low levels of awareness in Hong Kong." Journal of Gastroenterology and Hepatology 24, no. 11 (November 2009): 1786–90. http://dx.doi.org/10.1111/j.1440-1746.2009.05914.x.

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Fung, J., C. K. Lee, M. Chan, W. K. Seto, C. L. Lai, and M. F. Yuen. "1335 HIGH PREVALENCE OF NON-ALCOHOLIC FATTY LIVER DISEASE IN THE CHINESE – RESULTS FROM THE HONG KONG LIVER HEALTH CENSUS." Journal of Hepatology 58 (April 2013): S538. http://dx.doi.org/10.1016/s0168-8278(13)61335-5.

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Wong, Vincent Wai-Sun, Grace Lai-Hung Wong, David Ka-Wai Yeung, Tina Kit-Ting Lau, Carmen Ka-Man Chan, Angel Mei-Ling Chim, Jill M. Abrigo, et al. "Incidence of non-alcoholic fatty liver disease in Hong Kong: A population study with paired proton-magnetic resonance spectroscopy." Journal of Hepatology 62, no. 1 (January 2015): 182–89. http://dx.doi.org/10.1016/j.jhep.2014.08.041.

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Chan, Ruth, Vincent Wai-Sun Wong, Winnie Chiu-Wing Chu, Grace Lai-Hung Wong, Liz Sin Li, Jason Leung, Angel Mei-Ling Chim, et al. "Higher Estimated Net Endogenous Acid Production May Be Associated with Increased Prevalence of Nonalcoholic Fatty Liver Disease in Chinese Adults in Hong Kong." PLOS ONE 10, no. 4 (April 23, 2015): e0122406. http://dx.doi.org/10.1371/journal.pone.0122406.

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Wong, Vincent Wai-Sun, Winnie Chiu-Wing Chu, Grace Lai-Hung Wong, Ruth Suk-Mei Chan, Angel Mei-Ling Chim, Arlinking Ong, David Ka-Wai Yeung, et al. "Prevalence of non-alcoholic fatty liver disease and advanced fibrosis in Hong Kong Chinese: a population study using proton-magnetic resonance spectroscopy and transient elastography." Gut 61, no. 3 (August 16, 2011): 409–15. http://dx.doi.org/10.1136/gutjnl-2011-300342.

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Hao, Lei, Chih-Yu Chen, Jingxuan Kang, and Yonghui Nie. "Endogenous Omega-3 Polyunsaturated Fatty Acids Preserved Morphology and Function of Brown Fat Impaired by High-Fat Diet Feeding in Mice." Current Developments in Nutrition 5, Supplement_2 (June 2021): 1214. http://dx.doi.org/10.1093/cdn/nzab055_024.

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Abstract Objectives The role of omega-3 polyunsaturated fatty acids (PUFA) in regulation of energy homeostasis remains poorly understood. In this study, we aimed to investigate how omega-3 PUFA regulate the morphology and function of brown fat tissue (BAT) in mice. Methods Sixteen-week-old male wild type (WT) and transgenic fat-1 mice, which are capable of synthesizing omega-3 PUFA, were fed a low-fat diet (LFD) or a high-fat diet (HFD) for 13 weeks. Metabolic tissues, including BAT, white adipose tissues, and liver, were collected for biochemical and histological analysis. Results Transgenic fat-1 mice had significantly lower body weight and total fat mass compared with WT mic fed HFD. In addition, fat-1 mice had improved glucose tolerance compared with WT. We found that in WT mice, HFD induced larger lipid droplet accumulation (“whitening”) in BAT, whereas “whitening” in BAT was significantly alleviated in fat-1 mice. Real time PCR showed that some thermogenic markers, such as uncoupling protein 1 (UCP1), carnitine palmitoyltransferase I (CPT I), and cell death activator (CIDE-A), were expressed more in fat-1 mice compared with WT mice fed HFD. Moreover, fat-1 mice had significantly lower lipopolysaccharide levels compared with WT mice. Real time PCR showed that fat-1 mice had significantly lower levels of inflammatory markers, including monocyte chemoattractant protein-1 (MCP1), tumor necrosis factor (TNFα), and mouse macrophage marker (F4/80) in BAT. In a separate experiment, we found that fat-1 mice resisted UCP suppression by LPS injection. Conclusions This study demonstrated that HFD led to obesity and “whitening” of BAT in WT mice; conversely, omega-3 PUFA in fat-1 mice preserved morphology and function of BAT impaired by HFD. We revealed that the dysfunction of BAT may be attributed to increased LPS production due to HFD feeding, and that omega-3 PUFA alleviate the dysfunction of BAT through inhibition of LPS production. Funding Sources This study was supported by the Fortune Education Foundation (New York, USA) and Sansun Life Sciences (Hong Kong, China).
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Yeung, Dennis C. Y., Karen S. L. Lam, Yu Wang, Annette W. K. Tso, and Aimin Xu. "Serum Zinc-α2-Glycoprotein Correlates with Adiposity, Triglycerides, and the Key Components of the Metabolic Syndrome in Chinese Subjects." Journal of Clinical Endocrinology & Metabolism 94, no. 7 (July 1, 2009): 2531–36. http://dx.doi.org/10.1210/jc.2009-0058.

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Context: Zinc-α2-glycoprotein (ZAG) is a 40-kDa circulating glycoprotein secreted from the liver and adipose tissues. Animal studies have demonstrated the role of ZAG as a lipid-mobilizing factor involved in regulating lipid metabolism and adiposity. However, the clinical relevance of these findings remains to be established. Objective: This study aimed to address the relationship of serum ZAG levels with adiposity and cardiometabolic risk factors in humans. Design and Setting: A total of 258 Chinese subjects [aged 55.1 ± 12.5 yr; 120 males, 138 females; body mass index (BMI), 25.4 ± 4.1 kg/m2] were randomly selected from the population-based Hong Kong Cardiovascular Risk Factor Prevalence Study, based on their BMI. Serum ZAG levels were determined with ELISA. The relationship between serum ZAG levels and cardiometabolic parameters was assessed. Results: Serum ZAG levels were higher in men (P < 0.001 vs. women). Serum ZAG correlated positively with age, parameters of adiposity (waist circumference and BMI), fasting insulin, insulin resistance indices, serum triglycerides, adipocyte-fatty acid-binding protein, and C-reactive protein, and diastolic blood pressure (all P < 0.005, age- and sex-adjusted), and inversely with high-density lipoprotein-cholesterol levels (P = 0.008, age- and sex-adjusted). It was also elevated progressively with an increasing number of components of the metabolic syndrome (P for trend < 0.001). On multivariate analysis, serum ZAG was independently associated with male sex, the metabolic syndrome (or type 2 diabetes and serum triglycerides), and C-reactive protein (all P ≤ 0.002). Conclusions: ZAG might be involved in the pathogenesis of obesity-related metabolic disorders in humans and thus warrants further investigation.
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Shiu, Wesely C. T. "Primary liver cancer in Hong Kong." Cancer Chemotherapy and Pharmacology 31, S1 (1992): S143—S145. http://dx.doi.org/10.1007/bf00687124.

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Dissertations / Theses on the topic "Fatty Liver – Hong Kong"

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Lo, Chung-mau. "Application of living donor liver transplantation to adult recipients in Hong Kong /." Hong Kong : University of Hong Kong, 1998. http://sunzi.lib.hku.hk/hkuto/record.jsp?B20017492.

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Lo, Chung-mau, and 盧寵茂. "Application of living donor liver transplantation to adult recipients in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1998. http://hub.hku.hk/bib/B30257049.

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Wang, Clarissa Nicole. "Key processes of family resilience in families with long-term liver cancer survivors in Hong Kong." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42664548.

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Tang, Yuen-fong, and 鄧婉芳. "Retrospective evaluation of the Barcelona Clinic Liver Cancer staging classification and treatment schedule and development of a newprognostic staging system with treatment guidelines for Hong Kongpatients with hepatocellular carcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B47324089.

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There are a number of existing staging systems for patients with hepatocellular carcinoma (HCC). Yet, Barcelona Clinic Liver Cancer (BCLC) staging classification is the only one which suggests treatment guidance. Although BCLC staging is widely used in Western countries, it may not fit in the management of HCC patients in Hong Kong as they mostly have different etiologies and have more aggressive treatment strategy when compared with their counterparts in Western countries. It is aimed in this thesis to develop a new prognostic staging system in conjunction with treatment guidelines for HCC patients in Hong Kong. Three thousand eight hundred and fifty six adult HCC patients presented to the Department of Surgery, Queen Mary Hospital between January 1995 and December 2008 were included. The patient data were randomly separated into a training set and a test set for scheme development and performance assessment respectively. Four established prognostic factors which have determinative roles in treatment, namely Eastern Cooperative Oncology Group performance status, Child-Pugh grade, tumor status, and presence of extrahepatic vascular invasion/metastasis, were selected in building the scheme. Cox proportional hazards regression on overall survival was used to derive a relative coefficient for each category of these four factors. Clinical knowledge in addition to the relative coefficients was involved in the proposal of the prognostic stages. Then a classification and regression tree analysis was performed to elicit a set of simple clinical decision rules given the factors. This tree-structured classifier was adjusted with clinical judgment and reconciled with the proposed prognostic staging system for treatment guidelines. This Hong Kong Combined Liver Cancer (HKCLC) prognostic classification scheme stratifies patients to stages I to V with distinct overall survival outcomes. Its performance was compared to BCLC scheme for their discriminatory ability as staging systems and effectiveness of treatment guidelines. The former used receiver operating characteristics (ROC) analysis and concordance index as measures of the ability to distinguish patients with different prognosis for overall survival. HKCLC staging had significantly larger 1-year, 3-year and 5-year area under ROC curve values and higher concordance index vis-a-vis BCLC staging. The latter compared the overall survival of patients who received different treatments. The overall survival of patients with the same BCLC stage and the same HKCLC stage but received HKCLC recommended treatments were compared with those received BCLC recommended treatments by Kaplan-Meier plots and log-rank test. HKCLC treatment guidelines had wider indications for more aggressive treatments than the BCLC treatment schedule, and demonstrated significant survival benefit in our patients.
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Surgery
Master
Master of Philosophy
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Chan, See-ching, and 陳詩正. "Donor perspective of right lobe adult-to-adult live donor liver transplantation." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B34736414.

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陳雪梅 and Suet-mui Jessie Chan. "Pre-transplant model for end-stage liver disease (MELD) score as a predictor of post-liver transplant clinical outcome and resourceutilization at Queen Mary hospital (QMH) in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B4170955X.

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Yeung, Yuk-pang, and 楊玉鵬. "Natural history of untreated hepatocellular carcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B31972287.

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Wang, Clarissa Nicole, and 王允洵. "Key processes of family resilience in families with long-term liver cancer survivors in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B42664548.

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Geng, Ying. "The health-related quality of life of liver transplantation recipients in Hong Kong a follow-up and cross-sectional study /." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/HKUTO/record/B3955787X.

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Chan, Ka-yee, and 陳嘉儀. "Application of fatty acid profiles in field- and laboratory -based investigations of trophic relationships in Hong Kong wetland." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B48199436.

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 This study primarily aimed to evaluate the usefulness of fatty acids (FAs) in revealing trophic relationships in Hong Kong wetlands, through a combination of field studies and laboratory experiments. A field-based study in Mai Po mangroves involved FA profiling of basal food sources (i.e., leaf litter from three mangrove species, diatoms and macroalgae, and sediments) and consumers (particularly crabs). FA composition of all mangroves was similar, and lacked some polyunsaturated FAs present in diatoms and macroalgae. Uca and Sesarma crabs, with different feeding mechanisms, had divergent FA profiles: Uca arcuata FAs reflected a diet of macroalgae and diatoms, while FAs of Sesarma spp. were typical of mangrove leaves. Temporal changes in consumer FA profiles between 2001 and 2007 appeared attributable to increased sedimentation at Mai Po and shifts in organic content of the substratum. A second field-based study was conducted at Luk Keng marsh where a salinity gradient (0 to 30?) allowed investigation of the effects of salinity changes in FA profiles and stable isotope (carbon and nitrogen) signatures of the consumers and their foods. Basal food sources were leaf litter, including a fungal biomarker of decomposition (ergosterol), fine particulate organic matter (FPOM) and periphyton. Both FPOM and periphyton (but not leaf litter) contained 20:4 and 20:5 FAs, but their concentrations were affected by salinity. FA 20:4 occurred at higher levels in samples from fresh water, whilst FA 20:5 exhibited the opposite pattern and was more abundant under saline conditions, and thus the ratio of FA 20:4 to FA 20:5 decreased with increasing salinity. Combined application of FA biomarkers and isotopic signatures were able to elucidate trophic relationships between consumers and their food at Luk Keng confirming that FA 20:4 as a useful biomarker in the freshwater portion and FA 20:5 in the more saline area. FA 20:4 was particularly associated with predatory freshwater insects that had high δ15N values, but was scarce in primary consumers (snails, detritivorous beetles) with low δ15N values. Two laboratory experiments were undertaken to investigate: 1) the effect of diet on FA profiles in the apple snail, Pomacea canaliculata, and 2) interacting effects of diet and salinity on FA profiles of the Indian medaka fish, Oryzias melastigma. The results of the apple snail study showed that dietary-mediated changes in FA profiles were only reflected in the snail tissues after at least three months, and FA profiles of digestive tissues and neutral lipids were first to respond to the dietary change. The results of the medaka study demonstrated that the ratio of FA 20:4 to FA 20:5 was affected by both diet and salinity, reflecting a similar finding in the Luk Keng field study, although diet had a stronger effect on this ratio. The results of both field studies supported the use of FA profiles as food web tracers in wetlands and were complemented by laboratory results that yielded insights which will allow refinement of FA biomarker applications in food-web studies.
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Biological Sciences
Doctoral
Doctor of Philosophy
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Books on the topic "Fatty Liver – Hong Kong"

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Falk Symposium (90th 1996 Hong Kong). Update on hepatobiliary diseases 1996: Proceedings of the Falk Symposium no. 90, held in Hong Kong, February 29-March 1, 1996. Dordrecht: Kluwer Academic, 1996.

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Group, Residues Research, Acid Oils The Fatty Acids, and Oils The Fatty Acids Acid. The 2000 Import and Export Market for Fatty Acids, Acid Oils, and Residues in Hong Kong (World Trade Report). 2nd ed. Icon Group International, 2001.

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The Fresh and Frozen Dead and Edible Pou, Frozen Dead, The Fresh, and Edible Poultry Offals except Liver Research Group. The 2000 Import and Export Market for Fresh and Frozen Dead and Edible Poultry Offals except Liver in Hong Kong (World Trade Report). 2nd ed. Icon Group International, 2000.

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Book chapters on the topic "Fatty Liver – Hong Kong"

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Fan, Sheung-Tat, Chung-Mau Lo, Chi-Leung Liu, and William Ignace Wei. "Results of Living-Donor Liver Transplantation in Hong Kong." In Current Issues in Liver and Small Bowel Transplantation, 28–42. Tokyo: Springer Japan, 2002. http://dx.doi.org/10.1007/978-4-431-67889-2_6.

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Lai, Edward C. S., and John Wong. "Management of hepatocellular carcinoma in Hong Kong: The Queen Mary Hospital experience." In Primary Liver Cancer in Japan, 427–34. Tokyo: Springer Japan, 1992. http://dx.doi.org/10.1007/978-4-431-68177-9_43.

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Conference papers on the topic "Fatty Liver – Hong Kong"

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Chuah, Kee Huat, Lee Lee Lai, Nik Raihan Nik Mustapha, Sanjiv Mahadeva, and Wah Kheong Chan. "IDDF2019-ABS-0271 Liver stiffness measurement in non-alcoholic fatty liver disease: two is better than one." In International Digestive Disease Forum (IDDF) 2019, Hong Kong, 8–9 June 2019. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2019. http://dx.doi.org/10.1136/gutjnl-2019-iddfabstracts.300.

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Ng, Cheng Han, Jieling Xiao, Lincoln Kai En Lim, Darren Jun Hao Tan, Wen Hui Lim, Cyrus Ho, Eunice Xiang Xuan Tan, Arun Sanyal, and Mark Dinesh Muthiah. "IDDF2021-ABS-0008 Is fatty liver associated with depression? A meta-analysis and systematic review on prevalence, risk factors and outcomes of depression and non-alcoholic fatty liver disease." In Abstracts of the International Digestive Disease Forum (IDDF), Hong Kong, 4–5 September 2021. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2021. http://dx.doi.org/10.1136/gutjnl-2021-iddf.61.

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Wong, Martin MH, Kenneth Lo, and Wilson Tam. "IDDF2018-ABS-0120 The effect of OMEGA-3 fatty acid supplementation on paediatric non-alcoholic fatty liver disease: a meta-analysis of randomised controlled trials." In International Digestive Disease Forum (IDDF) 2018, Hong Kong, 9–10 June 2018. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2018. http://dx.doi.org/10.1136/gutjnl-2018-iddfabstracts.215.

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Huang, Xiaoqing, Changsheng Yan, Jingtong Wu, Xiang Zhang, and Jianlin Ren. "IDDF2019-ABS-0159 Oligofructose ameliorates nonalcoholic fatty liver disease by regulating gut microbiota dysbiosis in mice." In International Digestive Disease Forum (IDDF) 2019, Hong Kong, 8–9 June 2019. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2019. http://dx.doi.org/10.1136/gutjnl-2019-iddfabstracts.97.

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Zhang, Bangzhou, Lina Fan, Chuanxing Xiao, and Jianlin Ren. "IDDF2018-ABS-0162 Altered gut microbiota in experimental mouse models of non-alcoholic fatty liver disease." In International Digestive Disease Forum (IDDF) 2018, Hong Kong, 9–10 June 2018. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2018. http://dx.doi.org/10.1136/gutjnl-2018-iddfabstracts.19.

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Siu, Wilson, Yusuke Onishi, and Ashis Mukhopadhya. "IDDF2020-ABS-0088 Comparing non-invasive tests for prediction of fibrosis in non-alcoholic fatty liver disease." In Abstracts of the International Digestive Disease Forum (IDDF), 22–23 November 2020, Hong Kong. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2020. http://dx.doi.org/10.1136/gutjnl-2020-iddf.151.

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Lee, Hye Won, and Seung Up Kim. "IDDF2021-ABS-0046 Metabolic dysfunction-associated fatty liver disease increases colon cancer risk: a nationwide cohort study." In Abstracts of the International Digestive Disease Forum (IDDF), Hong Kong, 4–5 September 2021. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2021. http://dx.doi.org/10.1136/gutjnl-2021-iddf.14.

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Wang, Xiaoyong, and Jia Wu. "IDDF2018-ABS-0068 A potential link between polycystic ovary syndrome and non-alcoholic fatty liver disease: an update meta-analysis." In International Digestive Disease Forum (IDDF) 2018, Hong Kong, 9–10 June 2018. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2018. http://dx.doi.org/10.1136/gutjnl-2018-iddfabstracts.200.

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Li, Peifei, Keshu Shan, Yi Liu, Yu Zhang, Lu Xu, and Lei Xu. "IDDF2018-ABS-0074 CIRCSCD1 promotes fatty liver disease via the janus kinase 2/signal transducer and activator of transcription 5 pathway." In International Digestive Disease Forum (IDDF) 2018, Hong Kong, 9–10 June 2018. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2018. http://dx.doi.org/10.1136/gutjnl-2018-iddfabstracts.46.

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Thendiono, Eduward. "IDDF2021-ABS-0159 The effect of curcumin supplement among overweight/obese non-alcoholic fatty liver disease (NAFLD) patients." In Abstracts of the International Digestive Disease Forum (IDDF), Hong Kong, 4–5 September 2021. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2021. http://dx.doi.org/10.1136/gutjnl-2021-iddf.98.

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