Relevant bibliographies by topics / FDCs (Fixed Dose Combinations)

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'FDCs (Fixed Dose Combinations)'

Author: Grafiati
Published: 4 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "FDCs (Fixed Dose Combinations)"

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Supreet, Kamni, A. Naikwadi Akram, and Khot Anant. "An Evaluation of Fixed Dose Combinations (FDCs) Used for Treatment of Diabetes in Indian Market." International Journal of Current Research in Physiology and Pharmaocology 2, no. 1 (2018): 6–9. https://doi.org/10.5281/zenodo.2530830.

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Objective: To analyse the rationality of various FDCs used in the treatment Diabetes Mellitus and to find out the irrational FDCs existing in Indian market. Material and Methods: - Study Design: Analytical study. Data on FDC’s available in the Indian market was collected from Current Index of Medical Specialities (CIMS) and Monthly Index of Medical Specialities (MIMS) and their rationality was analysed using a pretested tool based on FDCs listed in WHO essential list of medicines and National List of Essential Medicines (NLEM), others based on their pharmacodynamic activity, Ph
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Gupta, Rohini, Apoorva Malhotra, and Pavan Malhotra. "Assessment of rational use of fixed dose combinations in hypertension in a tertiary care teaching hospital in north India." International Journal of Advances in Medicine 5, no. 5 (2018): 1263. http://dx.doi.org/10.18203/2349-3933.ijam20183905.

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Background: Fixed-dose combination (FDC) agents could be considered as an effective therapy in chronic illnesses like hypertension, which have multifactorial etiology. At present, many FDCs have come into the market without being assessed for their efficacy, safety and rationality by the drug regulatory authorities. The objective of the present study was to assess the rational use of fixed dose drug combinations in hypertension.Methods: It was a cross-sectional observational study conducted in the cardiology outpatient department of ASCOMS and H, Sidhra, Jammu, Jammu and Kashmir from February
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Aprajita, Rastogi, and Ramesh K. Goyal Prof. "Ban of Fixed Dose Combination on India Impact and Implications." International Journal of Trend in Scientific Research and Development 3, no. 5 (2019): 352–56. https://doi.org/10.5281/zenodo.3589769.

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Fixed dose combinations FDCs of drugs are important for public health perspective and commonly used for the treatment of pain and inflammation, hypertension, diabetes, malaria, tuberculosis, HIV AIDs etc. These ailments are considered to be the foremost threats to health in the world today. FDCs have proved to be advantageous as they are safe and effective. They increase efficiency, reduce the incidence of adverse drug effects, and improve patient compliance. The FDCs offer low cost as compared to individual components of active ingredients. On other hand if administered in unprofessional way,
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SS, Gill. "Guidelines on Fixed Dosage Combinations (FDCs): A Review." Bioequivalence & Bioavailability International Journal 7, no. 1 (2023): 1–4. http://dx.doi.org/10.23880/beba-16000197.

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Combination products, also known as fixed dose drug combinations (FDCs), are a combination of two or more active pharmacological components. In the US, the Food and Drug Administration defines a "product" as "any combination of a drug and a tool or a biological product." Regulatory Bodies, such as CDSCO, have laid down various rules and regulations on FDCs and classify them into four different types based on their origin status and have laid down requirements for FDCs under schedule Y and New Clinical Trials Rules 2019 along with rules such as rule 80.
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Jadhav, Sujata Abhay, Shaunak A. Pisal, Chitra C. Khanwelkar, Vandana M. Thorat, and Somnath M. Matule. "STUDY OF FIXED DOSE COMBINATIONS IN A TERTIARY CARE HOSPITAL." Asian Journal of Pharmaceutical and Clinical Research 9, no. 9 (2016): 35. http://dx.doi.org/10.22159/ajpcr.2016.v9s3.12615.

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ABSTRACTObjective: To study and analyze the pattern of fixed dose combinations (FDCs) in medicine outpatient clinic.Methods: The study is prospective cross-sectional study was conducted for 2 months in medicine outpatient clinic in tertiary care hospital. Aftertaking approval from Institutional Ethics Committee, the data were collected on every working day of the hospital. Prescriptions from the patientscoming to medicine outpatient clinic outpatient department were taken and required information is filled in data record form.Results: A total of 83 prescriptions were included in the study. Out
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Chukwunonso, C. Onwuzuligbo, and U. Onwuzuligbo Amarachukwu. "Fixed dose combination, a model therapy optimization strategy: A review." GSC Advanced Research and Reviews 20, no. 2 (2024): 036–46. https://doi.org/10.5281/zenodo.14948638.

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Therapy optimization involves a continuous improvement process of treatment interventions in the management of specific health challenges. Such optimization practices will not only help in achieving the desired treatment goals but will also improve the overall patients’ quality of life. One of the available therapy optimization strategy is the use of fixed dose combinations over monotherapies or poly-pharmacy. Fixed dose combination (FDC) is combination product that includes two or more active pharmaceutical ingredients (APIs) with similar or different pharmacological activity and differ
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Chukwunonso C Onwuzuligbo and Amarachukwu U Onwuzuligbo. "Fixed dose combination, a model therapy optimization strategy: A review." GSC Advanced Research and Reviews 20, no. 2 (2024): 036–46. http://dx.doi.org/10.30574/gscarr.2024.20.2.0296.

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Therapy optimization involves a continuous improvement process of treatment interventions in the management of specific health challenges. Such optimization practices will not only help in achieving the desired treatment goals but will also improve the overall patients’ quality of life. One of the available therapy optimization strategy is the use of fixed dose combinations over monotherapies or poly-pharmacy. Fixed dose combination (FDC) is combination product that includes two or more active pharmaceutical ingredients (APIs) with similar or different pharmacological activity and different me
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Chaudhry, Sunil. "Fixed dose combinations in India- what a way to go!" Indian Journal of Pharmacy and Pharmacology 10, no. 1 (2023): 45–49. http://dx.doi.org/10.18231/j.ijpp.2023.012.

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Fixed dose combinations (FDCs) are generally considered desirable options in chronic diseases such as tuberculosis, cardiovascular diseases & diabetes, tropical diseases such as malaria & in HIV and in Cancer. FDCs are useful in chronic conditions especially when multiple disorders often co-exist The advantages of the FDC are basically patients compliance, simple dosage schedule, better efficacy, cheaper shipment & packaging activities. The drawbacks of FDCs are (a) Pharmacodynamic mismatch between the two ingredients, one drug having additive/antagonistic effect leading to reduced
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Garg, Ram Ishwar, Gladson David Masih, and Bikash Medhi. "Nanoformulation and Fixed Dose Combination." International Journal of Pharmaceutical Sciences and Nanotechnology(IJPSN) 18, no. 2 (2025): 7897–901. https://doi.org/10.37285/ijpsn.2024.18.2.1.

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Nanoformulation refers to the design of drug delivery systems at the nanoscale to enhance solubility, stability, and bioavailability. According to the U.S. Food and Drug Administration (FDA), nanoformulation refers to the design and development of drug delivery systems with components in the nanoscale range (typically 1-100 nanometers), where the unique physiochemical properties at this scale are leveraged to enhance therapeutic efficacy, improve bioavailability, and enable targeted delivery1. FDC (Fixed-Dose Combination) combines two or more drugs in a single dosage form. As defined by the Ce
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Ravichandran, Aravind, Jayapriya Balamurugan, Shankareshwari, and Ramalingam Sekar. "Knowledge, attitude and prescriptional practice about fixed dose combinations among medical practitioners in tertiary care hospital." International Journal of Basic & Clinical Pharmacology 6, no. 8 (2017): 1937. http://dx.doi.org/10.18203/2319-2003.ijbcp20173274.

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Background: Fixed dose combination (FDC) are currently most prescribed and misused drug forms. Although fixed dose combinations are clinically better than single dosage forms, improper prescription and large amounts of irrational FDC flooding leads to unwanted financial burden and increased resistance. Therefore a study was carried out to know about the existing scenario about Knowledge Attitude and Practice of Fixed dose combinations among the resident doctors and devise some suggestions for improving the rationality. The objective of the study was to evaluate the knowledge, attitude and pres
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Dissertations / Theses on the topic "FDCs (Fixed Dose Combinations)"

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Dennison, Thomas. "Orally disintegrating tablets : formulation development, novel engineering solutions and fixed dose combinations." Thesis, Aston University, 2017. http://publications.aston.ac.uk/30817/.

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Orally disintegrating tablets (ODTs) are an attractive solid dosage form for patients who suffer from dysphagia, a difficulty in swallowing, which is particularly prevalent in paediatric and geriatric populations. ODTs and fixed dose combination (FDC) formulations are popular as they improve patient compliance and combination of the two has not previously been explored. The requirement for ODTs to disintegrate rapidly whilst also being mechanically robust means that high drug loading is a significant challenge. An ODT formulation for the betalactam antibiotic flucloxacillin was developed at do
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Anupindi, Vamshi Ruthwik. "Cost Utility Analysis of Fixed Dose and Free Dose Combinations of Oral Medications in Type 2 Diabetes Patients." University of Toledo Health Science Campus / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=mco1438889070.

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Obua, Celestino. "Fixed-dose chloroquine and sulfadoxine/pyrimethamine treatment of malaria : outcome and pharmacokinetic aspects /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-144-9/.

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Yngman, Gunnar. "Individualization of fixed-dose combination regimens : Methodology and application to pediatric tuberculosis." Thesis, Uppsala universitet, Institutionen för farmaceutisk biovetenskap, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-242059.

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Introduction: No Fixed-Dose Combination (FDC) formulations currently exist for pediatric tuberculosis (TB) treatment. Earlier work implemented, in the software NONMEM, a rational method for optimizing design and individualization of pediatric anti-TB FDC formulations based on patient body weight, but issues with parameter estimation, dosage strata heterogeneity and representative pharmacokinetics remained. Aim: To further develop the rational model-based methodology aiding the selection of appropriate FDC formulation designs and dosage regimens, in pediatric TB treatment. Materials and Methods
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Botelho, Fernanda Alves. "Desenvolvimento e validação de metodologia analítica para a determinação de tuberculostáticos de dose fixa combinada (FDC) e suas substâncias relacionadas." reponame:Repositório Institucional da FIOCRUZ, 2013. https://www.arca.fiocruz.br/handle/icict/13447.

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Made available in DSpace on 2016-04-04T12:26:00Z (GMT). No. of bitstreams: 2 2.pdf: 3729000 bytes, checksum: 78661b59dc7c742033ca6ce5a153cc47 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2013<br>Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos/Farmanguinhos. Rio de Janeiro, RJ, Brasil.<br>O crescimento do número de casos de tuberculose no Brasil fez com que o Governo Federal desenvolvesse uma política nacional de controle da tuberculose que possibilitasse melhorar e prolongar a qualidade de vida dos indivíduos infectados. Esta
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Malik, Farrukh Javaid. "Analysis of the medicines panorama in Pakistan : The case of antimicrobials : market offer width and consumption." Thesis, Bordeaux, 2019. http://www.theses.fr/2019BORD0266.

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Le marché du médicament d’un pays est un indicateur de son système de santé, de son profil épidémiologique et des pratiques [de prescription] qui y règnent. Il ne s'agit pas seulement de la première étape logique pour étudier les caractéristiques des médicaments autorisés à la commercialisation, mais aussi d’une condition préalable pour la mise en place d'un système de pharmacovigilance qui favorise une utilisation rationnelle des médicaments. Les trois études de marché sur les médicaments présentées dans le présent document ont été réalisées au Pakistan avec l’objectif de décrire les caractér
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Sadia, M., Abdullah Isreb, I. Abbadi, et al. "From ‘fixed dose combinations’ to ‘a dynamic dose combiner’: 3D printed bi-layer antihypertensive tablets." 2018. http://hdl.handle.net/10454/17413.

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Yes<br>There is an increased evidence for treating hypertension by a combination of two or more drugs. Increasing the number of daily intake of tablets has been reported to negatively affect the compliance of patients. Therefore, numerous fixed dose combinations (FDCs) have been introduced to the market. However, the inherent rigid nature of FDCs does not allow the titration of the dose of each single component for an individual patient's needs. In this work, flexible dose combinations of two anti-hypertensive drugs in a single bilayer tablet with a range of doses were fabricated using dual fu
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Yeh, Ya-Ting, and 葉雅婷. "Prescription patterns and impact on patients’ medication adherence of fixed-dose antihypertensive combinations in Taiwan." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/90184825888191182000.

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碩士<br>國防醫學院<br>藥學研究所<br>99<br>Objective: The aims of this study were to investigate the reimbursement and prescription patterns of fixed-dose antihypertensive combinations (FDCs) in Taiwan. The medication possession ratio (MPR) of patients using FDCs was compared to that of patients using free antihypertensive combinations. The medication adherence among two groups was also compared, with the covariates adjusted. Methods: This was a retrospective, population-based cohort study. A 1,000,000 cohort randomly collected from the National Health Insurance (NHI) claimed database between January 1997
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Chiu, Chien-Tung, and 邱建通. "Efficacy and adverse effect of Fixed-dose combinations versus separate formulations in tuberculosis treatment under DOTS program." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/60580433165170790040.

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碩士<br>高雄醫學大學<br>公共衛生學研究所<br>101<br>Fixed-dose combinations (FDCs) of anti-tuberculosis drugs, which simplify the prescription of drugs and prevent the development of drug resistance, have been recommended as a standard anti-tuberculosis treatment regimen. However, the composition and dosage recommendation of FDCs are different from separate formulations (SF) and this is a major concern of clinicians. Referring previous study, the FDCs has fewer adverse effects without directly observed treatment short-course (DOTS) program. Whether the advantage of FDCs is still present under the DOTS program.
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Simão, João Daniel Nunes. "Internship Report and Monograph entitled "Development of bilayer tablets by Quality by Design: Focus on Manufacturing parameters"." Master's thesis, 2021. http://hdl.handle.net/10316/99136.

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Relatório de Estágio do Mestrado Integrado em Ciências Farmacêuticas apresentado à Faculdade de Farmácia<br>O presente documento é constituído pelo Relatório de Estágio em Farmácia Comunitária e pela Monografia intitulada "Desenvolvimento de comprimidos de dupla camada através duma estratégia de Qualidade Programada: foco nos parâmetros de fabrico"Sendo parte do plano curricular do último semestre do Mestrado Integrado em Ciências Farmacêuticas, o Estágio em Farmácia Comunitária decorreu na Farmácia Estádio, em Coimbra, entre janeiro e setembro de 2021 e é apresentado sob a forma de uma anális
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Books on the topic "FDCs (Fixed Dose Combinations)"

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Mitra, Amitava, and Ali R. Rajabi-Siahboomi. Fixed Dose Combinations for Solid Oral Drug Delivery. Wiley & Sons, Incorporated, John, 2019.

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Mitra, Amitava, and Ali R. Rajabi-Siahboomi. Fixed Dose Combinations for Solid Oral Drug Delivery. Wiley & Sons, Incorporated, John, 2019.

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Mitra, Amitava, and Ali R. Rajabi-Siahboomi. Fixed Dose Combinations for Solid Oral Drug Delivery. Wiley & Sons, Incorporated, John, 2019.

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Assessment of Fixed Dose Combinations in Cardiovascular Diseases. Independently Published, 2020.

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Book chapters on the topic "FDCs (Fixed Dose Combinations)"

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Paul, Abialbon. "Fixed-Dose Combinations." In Introduction to Basics of Pharmacology and Toxicology. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-32-9779-1_21.

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Dharmagadda, Sreedhar. "Fixed-Dose Combinations: Innovations and Research." In Recent Advances in Pharmaceutical Innovation and Research. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-2302-1_18.

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Caldwell, W. Brett, and Aditya M. Kaushal. "Multiparticulate Technologies for Fixed-Dose Combinations." In Advances in Delivery Science and Technology. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7012-4_7.

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Volpe, Massimo, Giuliano Tocci, and Giovanna Gallo. "Use of Fixed-Dose Combinations in Hypertension and Cardiovascular Disease Prevention." In Drug Adherence in Hypertension and Cardiovascular Protection. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-76593-8_17.

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"Fixed-Dose Combinations (FDCs) and Co-Packaging." In Pharmaceutical Lifecycle Management. John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9781118266755.ch16.

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Yadav, Pramila, Vaishali Thakre, and Pradnya Deolekar. "Fixed Dose Combination (FDC)." In Practical Pharmacology. Jaypee Brothers Medical Publishers (P) Ltd., 2018. http://dx.doi.org/10.5005/jp/books/13114_6.

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Mohanta, Guru, and Praveen Tavva. "Fixed Dose Combinations." In Handbook of Medicine for Pharmacists. Jaypee Brothers Medical Publishers (P) Ltd., 2014. http://dx.doi.org/10.5005/jp/books/12322_14.

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Darbar, Soumendra, Srimoyee Saha, Kausikisankar Pramanik, and Atiskumar Chattopadhyay. "Haematological Modulations by Fixed Dose Combination (FDC) of Tramadol Hydrochloride/Paracetamol (THP)." In Frontiers in Clinical Drug Research: Hematology: Volume 5. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815039535122050007.

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Shahid, Imran, and Qaiser Jabeen. "Current Landscape of HCV Therapeutics." In Hepatitis C Virus-Host Interactions and Therapeutics: Current Insights and Future Perspectives. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815123432123010009.

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During the last decade, the advent and approval of almost a dozen all-oral interferon-free direct-acting antivirals (IFN-free DAAs) to cure hepatitis C-infected general and harder-to-treat populations have entirely changed the treatment paradigms against this “silent epidemic”. The clinical trials of generic IFN-free DAAs, while achieving 95% to 100% sustained virologic response rates (SVRs) in treated individuals, have proven their worth as “magic pills” in hepatitis C therapeutics. Following their real-world clinical usage data with SVR rates, more than 95% have raised the hopes to treat eve
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Ejaz, Mahnoor, Areena Suhail Khan, Faiza Naseer, and Alvina Gul. "Metabolic Syndromes." In Omics Technologies for Clinical Diagnosis and Gene Therapy: Medical Applications in Human Genetics. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815079517122010018.

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Metabolic Syndromes (MetS) are recognized as a cluster of risk factors which are known to increase the likelihood of obesity, type 2 diabetes (T2D) and cardiovascular disorders (CVDs). It is significant to understand disease pathology in order to discover a pathological mechanism leading to the development of MetS. Elevated triglycerides, increased blood pressure, hyperglycemia (increased blood glucose levels), low levels of High-density lipoprotein (HDL) cholesterol and elevated waist circumference are key parameters in diagnosing MetS. Various therapeutic interventions have been developed fo
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Conference papers on the topic "FDCs (Fixed Dose Combinations)"

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Al-Hashem, A., M. Salman, and K. Al-Muhanna. "Scale Inhibitor Evaluation for an Effluent Injection System in West Kuwait." In CORROSION 2000. NACE International, 2000. https://doi.org/10.5006/c2000-00330.

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Abstract Six scale inhibitors were evaluated to reduce the scaling tendency of an effluent water produced from the western zone of the Kuwait Oil Fields, commingled with three different formation waters. The effluent water to formation water ratios for each of the water combinations under study were chosen to reflect worst case conditions, as predicted from a computer compatibility study. In this study, static autoclave jar tests were conducted prior to dynamic scaling tests in order to select an appropriate dose concentration for the inhibitors. All scale inhibitors were tested under reservoi
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Ansbro, E., S. Masri, D. Prieto-Merino, et al. "Fixed dose combination drugs for cardiovascular disease in Lebanon." In MSF Scientific Days International 2022. MSF-USA, 2022. http://dx.doi.org/10.57740/8697-vn33.

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INTRODUCTION Cardiovascular disease (CVD) is the leading cause of death and disability globally, including in humanitarian contexts. Fixed-dose combination (FDC) drugs are cost-effective for primary and secondary prevention of CVD. From 2012 until the end of 2020, MSF provided care for CVD patients from Syrian refugee and host populations in primary care clinics in Tripoli, north Lebanon. In this implementation study, we assessed whether FDC use is linked with adherence to CVD medications and treatment simplification in a humanitarian setting. METHODS Our prospective, before-and-after cohort s
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Dejesus, Edwin, Soundos Saleh, Dorina Van Der Mey, et al. "Pharmacokinetic (PK) interaction of fixed-dose combination (FDC) antiretrovirals (ARV) with riociguat (rio)." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa3036.

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Mustafa, Fadhil Ilham, Nurfitri Bustamam, and Andri Pramesyanti. "Association between Compliance Level on Fixed-Dose Combination Antiretroviral Drug and CD4 Level among HIV Patients." In The 7th International Conference on Public Health 2020. Masters Program in Public Health, Universitas Sebelas Maret, 2020. http://dx.doi.org/10.26911/the7thicph.02.03.

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Background: People living with HIV / AIDS (PLWHA) have weak immune systems and are prone to infection. Therefore, PLWHA must take antiretroviral (ARV) to maintain their immunity. This study aimed to determine the relationship between the level of adherence to taking ARV fixed-dose combination (FDC) drugs and CD4 levels of HIV patients. Subjects and Method: This was a cross-sectional study conducted at Pengayoman Cipinang Hospital, Indonesia, in 2018. Total of 91 HIV patient over 17 years of age, had or had received FDC ARV therapy for at least 1 year, and did not experience drug-induced hepati
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Mejri, Insaf, Manel Loukil, Ikbelle Khalfallah, and Hedia Ghrairi. "Side effects of tuberculosis treatment with fixed-dose combinations." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa2713.

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Qazi, Sanjive, Lynne Murphy, Anshuma Mehta, et al. "Abstract 2597: Celecoxib fixed dose combinations - patient level data analyses." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-2597.

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Capel, Margarita, Maria Mareque, Carlos Jose Alvarez, Leandro Lindner, and Itziar Oyagüez. "Cost-effectiveness of fixed-dose combinations therapies for COPD in Spain." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa2792.

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Madhuri, Kolla, Saswat Subhankar, and Debee Prasad Dash. "A Study on Various Types of Presentations of Paediatric Tuberculosis and Response to Fixed Dose Combination (FDC)." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.1566.

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Jansa, Pavel, Kelly Chin, Ekkehard Grünig, et al. "Macitentan tadalafil fixed dose combination (FDC) in patients with pulmonary arterial hypertension (PAH): A subgroup analysis from A DUE." In ERS International Congress 2023 abstracts. European Respiratory Society, 2023. http://dx.doi.org/10.1183/13993003.congress-2023.pa1196.

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Price, David, William Henley, Victoria Carter, et al. "Late Breaking Abstract - Pneumonia risk in COPD patients initiating extrafine Fixed Dose Combination (FDC) with beclometasone dipropionate (ef-FDC-BDP) versus long-acting bronchodilators (LABD)." In ERS International Congress 2021 abstracts. European Respiratory Society, 2021. http://dx.doi.org/10.1183/13993003.congress-2021.pa560.

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