Academic literature on the topic 'Fe metabolism'

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Journal articles on the topic "Fe metabolism"

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Olakanmi, Oyebode, Bradley E. Britigan, and Larry S. Schlesinger. "Gallium Disrupts Iron Metabolism of Mycobacteria Residing within Human Macrophages." Infection and Immunity 68, no. 10 (2000): 5619–27. http://dx.doi.org/10.1128/iai.68.10.5619-5627.2000.

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ABSTRACT Mycobacterium tuberculosis and M. aviumcomplex (MAC) enter and multiply within monocytes and macrophages in phagosomes. In vitro growth studies using standard culture media indicate that siderophore-mediated iron (Fe) acquisition plays a critical role in the growth and metabolism of both M. tuberculosis and MAC. However, the applicability of such studies to conditions within the macrophage phagosome is unclear, due in part to the absence of experimental means to inhibit such a process. Based on the ability of gallium (Ga3+) to concentrate within mononuclear phagocytes and on evidence
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Chen, Yao, Fangxu Jia, Yingjie Liu, et al. "The effects of Fe(III) and Fe(II) on anammox process and the Fe–N metabolism." Chemosphere 285 (December 2021): 131322. http://dx.doi.org/10.1016/j.chemosphere.2021.131322.

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Mendonca, Caroll M., Sho Yoshitake, Hua Wei, et al. "Hierarchical routing in carbon metabolism favors iron-scavenging strategy in iron-deficient soilPseudomonasspecies." Proceedings of the National Academy of Sciences 117, no. 51 (2020): 32358–69. http://dx.doi.org/10.1073/pnas.2016380117.

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High-affinity iron (Fe) scavenging compounds, or siderophores, are widely employed by soil bacteria to survive scarcity in bioavailable Fe. Siderophore biosynthesis relies on cellular carbon metabolism, despite reported decrease in both carbon uptake and Fe-containing metabolic proteins in Fe-deficient cells. Given this paradox, the metabolic network required to sustain the Fe-scavenging strategy is poorly understood. Here, through multiple13C-metabolomics experiments with Fe-replete and Fe-limited cells, we uncover how soilPseudomonasspecies reprogram their metabolic pathways to prioritize si
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Roodenburg, Annet J. C., Clive E. West, Shiguang Yu, and Anton C. Beynen. "Comparison between time-dependent changes in iron metabolism of rats as induced by marginal deficiency of either vitamin A or iron." British Journal of Nutrition 71, no. 5 (1994): 687–99. http://dx.doi.org/10.1079/bjn19940176.

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To compare the changes in Fe metabolism during the development of vitamin A and Fe deficiencies, rats were given either a control diet with sufficient Fe (35 mg added Fe/kg feed) and retinol (1200 retinol equivalents/kg feed), a diet without added vitamin A or a diet with sufficient vitamin A but only 3.5 mg added Fe/kg feed. During a period of 10 weeks, indicators of vitamin A and Fe status were monitored. Neither vitamin A nor Fe deficiency produced clinical signs. Fe deficiency induced an immediate fall in blood haemoglobin concentration. Vitamin A deficiency produced a mild anaemia as the
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Dewey, Kathryn G., and Camila M. Chaparro. "Session 4: Mineral metabolism and body composition Iron status of breast-fed infants." Proceedings of the Nutrition Society 66, no. 3 (2007): 412–22. http://dx.doi.org/10.1017/s002966510700568x.

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Fe deficiency is a common nutritional disorder during infancy, particularly in low-income countries. The Fe status of a breast-fed infant is strongly influenced by the body Fe content at birth, which is determined by factors that operate before birth (maternal Fe status before and during pregnancy; infant gestational age and birth weight) and at the time of delivery (the timing of umbilical cord clamping). Delaying the clamping of the umbilical cord for 2 min can increase body Fe content by approximately 33% (75 mg), and results in greater Fe stores at 6 months of age. After birth, male gender
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Becker, Erika M., Judith M. Greer, Prem Ponka, and Des R. Richardson. "Erythroid differentiation and protoporphyrin IX down-regulate frataxin expression in Friend cells: characterization of frataxin expression compared to molecules involved in iron metabolism and hemoglobinization." Blood 99, no. 10 (2002): 3813–22. http://dx.doi.org/10.1182/blood.v99.10.3813.

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Friedreich ataxia (FA) is caused by decreased frataxin expression that results in mitochondrial iron (Fe) overload. However, the role of frataxin in mammalian Fe metabolism remains unclear. In this investigation we examined the function of frataxin in Fe metabolism by implementing a well-characterized model of erythroid differentiation, namely, Friend cells induced using dimethyl sulfoxide (DMSO). We have characterized the changes in frataxin expression compared to molecules that play key roles in Fe metabolism (the transferrin receptor [TfR] and the Fe transporter Nramp2) and hemoglobinizatio
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Sparreboom, Alex, Sharon Marsh, Ron H. J. Mathijssen, Jaap Verweij, and Howard L. McLeod. "Pharmacogenetics of tipifarnib (R115777) transport and metabolism in cancer patients." Investigational New Drugs 22, no. 3 (2004): 285–89. http://dx.doi.org/10.1023/b:drug.0000026254.97350.fe.

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Liu, Zhi-Pan, and P. Hu. "Mechanism of H2 metabolism on Fe-only hydrogenases." Journal of Chemical Physics 117, no. 18 (2002): 8177–80. http://dx.doi.org/10.1063/1.1519252.

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Andersen, Henriette S., Lorraine Gambling, Grietje Holtrop, and Harry J. McArdle. "Effect of dietary copper deficiency on iron metabolism in the pregnant rat." British Journal of Nutrition 97, no. 2 (2007): 239–46. http://dx.doi.org/10.1017/s0007114507239960.

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Cu and Fe metabolism are known to be linked, but the interactions during pregnancy are less well studied. In the present study we used rats to examine the effect of Cu deficiency during pregnancy on Fe and Cu levels in maternal and fetal tissue and on the gene expression profile of proteins involved in Cu and Fe metabolism in the placenta. Rats were fed diets with different Cu contents before and during pregnancy. Samples were collected on day 21 of gestation. Cu levels, ceruloplasmin activity and serum Fe all decreased in maternal serum of Cu-deficient animals. Maternal liver Fe inversely cor
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WATTS, Ralph N., Prem PONKA, and Des R. RICHARDSON. "Effects of nitrogen monoxide and carbon monoxide on molecular and cellular iron metabolism: mirror-image effector molecules that target iron." Biochemical Journal 369, no. 3 (2003): 429–40. http://dx.doi.org/10.1042/bj20021302.

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Many effector functions of nitrogen monoxide (NO) and carbon monoxide (CO) are mediated through their high-affinity for iron (Fe). In this review, the roles of NO and CO are examined in terms of their effects on the molecular and cellular mechanisms involved in Fe metabolism. Both NO and CO avidly form complexes with a plethora of Fe-containing molecules. The generation of NO and CO is mediated by the nitric oxide synthase and haem oxygenase (HO) families of enzymes respectively. The effects of NO on Fe metabolism have been well characterized, whereas knowledge of the effects of CO remains wit
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Dissertations / Theses on the topic "Fe metabolism"

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Moshtaghie, A. A. "Interrelationships between aluminium and iron metabolism in man." Thesis, University of Newcastle Upon Tyne, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.380213.

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Burwick, John E. "O2, Fe(III) mineral phase and depth controls on Fe metabolism in acid mine drainage derived iron mounds." University of Akron / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=akron1436335313.

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Ramirez, Melissa V. "Probing Plant Metabolism: The Machineries of [Fe-S] Cluster Assembly and Flavonoid Biosynthesis." Diss., Virginia Tech, 2008. http://hdl.handle.net/10919/77167.

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The organization of metabolism is an essential feature of cellular biochemistry. Metabolism does not occur as a linear assembly of freely diffusing enzymes, but as a complex web in which multiple interactions are possible. Because of the crowded environment of the cell, there must be structured and ordered mechanisms that control metabolic pathways. The following work will examine two metabolic pathways, one that is ubiquitous among living organisms and another that is entirely unique to plants, and examine the organization of each in an attempt to further define mechanisms that are fundamenta
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Andersson, Charlotta Selina. "Structural studies of R2 and R2–like proteins with a heterodinuclear Mn/Fe cofactor and enzymes involved in Mycobacterium tuberculosis lipid metabolism." Doctoral thesis, Stockholms universitet, Institutionen för biokemi och biofysik, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-75750.

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Tuberculosis is a notorious disease responsible for the deaths of 1.4 million people worldwide. A third of the world's population is infected with Mycobacterium tuberculosis, the bacterium causing the disease. The increase of multi drug-resistant strains worsens the situation, and the World Health Organization has declared tuberculosis to be a global emergency. The bacterium envelopes itself with a unique set of very long-chain lipids that play an important role in virulence and drug resistance. Therefore enzymes involved in lipid metabolism are putative drug targets.  To allow entry into diff
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Thomas, Carla. "The validation and use of the rat intestinal epithelial cell line 6 (IEC-6) to study the role of ferroportin1 and divalent metal transporter 1 in the uptake of iron from Fe(II) and Fe(III)." University of Western Australia. Physiology Discipline Group, 2003. http://theses.library.uwa.edu.au/adt-WU2004.0019.

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[Formulae and special characters can only be approximated here. Please see the pdf version of the abstract for an accurate reproduction.] Iron is vital for almost all living organisms by participating in a wide variety of metabolic processes, including oxygen transport, DNA synthesis, and electron transport. However, iron concentrations in body tissues must be tightly regulated because excessive iron leads to tissue damage, as a result of formation of free radicals. In mammals since no controlled means of eliminating unwanted iron has evolved, body iron balance is maintained by alterations i
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Belrhali, Hassan. "Détermination par cristallographie aux rayons X des mécanismes de formation du séryl-adénylate et du bis(5'-adénosyl) tétraphosphate par la séryl-ANRt synthétase de Thermus Thermophilus." Grenoble 1, 1996. http://www.theses.fr/1996GRE10054.

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Les aminoacyl-arnt synthetases sont une famille d'enzymes qui jouent un role clef dans le processus de biosynthese des proteines. Nous presentons dans ce travail les bases structurales du mecanisme de reconnaissance et d'activation de la serine par la seryl-arnt synthetase de thermus thermophilus
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Baldet, Pierre. "Quelques observations sur le métabolisme de la biotine chez les plantes supérieures." Grenoble 1, 1993. http://www.theses.fr/1993GRE10054.

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Seuls les microorganismes et les plantes sont capables de produire la biotine. La voie de biosynthese de la biotine (vitamine h), bien connue chez les bacteries, n'a encore jamais ete etablie chez les vegetaux superieurs. Dans les differents compartiments subcellulaires (chloroplastes, mitochondries, cytosol et vacuoles) de feuilles de pois (pisum sativum l. ), la biotine libre est localisee dans le cytosol alors que la biotine liee aux proteines est presente dans les chloroplastes et les mitochondries. La biotine liee est associee a trois polypeptides de 34, 76 et 220 kda. Les polypeptides de
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Beuf, Laurent. "Recherche des gènes impliqués dans l'assimilation du carbone inorganique chez Synechocystis PCC 6803." Aix-Marseille 2, 1993. http://www.theses.fr/1993AIX22078.

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Le carbone inorganique (ci) est la source de carbone utilisee par les cyanobacteries pour synthetiser les constituants organiques necessaires a leur croissance. Un systeme de transport actif ainsi que des activites anhydrase carbonique (ac) sont impliquees dans ce processus. Chez synechocystis pcc6803, ces dernieres sont regulees par la concentration en ci externe. Elles representent un cas interessant pour l'etude de la regulation de l'assimilation du ci. On a cherche a isoler un gene d'ac par deux approches differentes. La premiere, l'utilisation de sondes oligonucleotidiques deduites de seq
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Evrard, Adeline. "Développements de la spectroscopie RMN en biologie structurale et métabolique : études de la protéine SiR-FP60 et du métabolisme végétal." Université Joseph Fourier (Grenoble), 1999. http://www.theses.fr/1999GRE10070.

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Ce travail se divise en deux parties distinctes, rmn structurale a une dimension et rmn metabolique a une et deux dimensions. Dans une premiere partie, une analyse quantitative de spectres phosphores de la proteine sir-fp60 native et dans des etats redox connus nous a permis d'ebaucher une structure du site actif de la nadp sulfite reductase (sir). Dans une deuxieme partie, la quantification des spectres d'extraits acides cellulaires de pointes de racines de mais excisees et l'analyse quantitative d'experiences in-vivo nous ont permis d'etudier le signal-sucre et la transition normoxie-anoxie
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Casas, Herranz Celia. "Rcs1 como factor transcripcional implicado en la asimilación de hierro y el metabolismo respiratorio en Saccharomyces cerevisiae." Doctoral thesis, Universitat de Lleida, 1996. http://hdl.handle.net/10803/8089.

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El hierro es un elemento imprescindible para los seres vivos. En la naturaleza<br/>se encuentra fundamentalmente en forma de Fe(lll) formando parte de sales e<br/>hidróxidos de muy baja solubilidad, lo que lo hace biológicamente inaccesible para los<br/>seres vivos mediante mecanismos simples de asimilación. En su forma reducida, el<br/>Fe(ll) es mucho más soluble, pero también muy inestable, pasando immediatamente<br/>a Fe(lll) en presencia de oxígeno. Por otro lado, el hierro puede resultar tóxico para la<br/>célula a concentraciones superiores a las requeridas por ésta, hecho éste que ha<br
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Books on the topic "Fe metabolism"

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Chénier, Daniel. Aluminum toxicity in Pseudomonas fluorescens: The modulation of Fe-protein and metabolic networks. Laurentian University, School of Graduate Studies, 2004.

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Book chapters on the topic "Fe metabolism"

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Lentini, Christopher J. "Mineralogical Controls on Microbial Reduction of Fe(III) (Hydr)oxides." In Microbial Metal and Metalloid Metabolism, edited by Colleen M. Hansel. ASM Press, 2014. http://dx.doi.org/10.1128/9781555817190.ch6.

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Edwards, Ashley M., Maame A. Addo, and Patricia C. Dos Santos. "tRNA Modifications as a Readout of S and Fe-S Metabolism." In Methods in Molecular Biology. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1605-5_8.

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Buckhout, Thomas J. "DNA microarray analysis of primary metabolism in Fe-deficient Arabidopsis roots and shoots." In Wurzelinduzierte Bodenvorgänge. Vieweg+Teubner Verlag, 2004. http://dx.doi.org/10.1007/978-3-322-80084-8_3.

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"Fe Metabolism." In Encyclopedia of Metalloproteins. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-1533-6_100507.

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Benarroch, Eduardo E. "Mitochondria and Energy Metabolism." In Neuroscience for Clinicians, edited by Eduardo E. Benarroch. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780190948894.003.0011.

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Mitochondria are membranous organelles critical for survival and function of neurons and other cells in the nervous system and many other tissues. Their main functions include production of ATP by oxidative phosphorylation, signaling via reactive oxygen species; intracellular calcium (Ca<sup>2+</sup>) homeostasis; synthesis of iron-sulfur (Fe-S) clusters; metabolism of lipids and amino acids, and synthesis of nucleotides, and heme. Maintenance of normal mitochondrial function and distribution is known as mitostasis, and requires highly regulated processes of mitochondrial biogenesis and quality control, fusion/fission, transport, and mitophagy. Mitochondrial dysfunction is a critical mechanism of neurologic diseases. They include disorders directly affecting OXPHOS and metabolic functions; primary disorders of mitostasis; and most adult-onset neurodegenerative disorders indirectly affecting mitostasis through defects in axonal transport and autophagy.
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JOHNSON, GORDON V., and LARRY L. BARTON. "SELECTED PHYSIOLOGICAL RESPONSES ASSOCIATED WITH FE(III) AND FE(II) METABOLISM." In Iron Chelation in Plants and Soil Microorganisms. Elsevier, 1993. http://dx.doi.org/10.1016/b978-0-12-079870-4.50022-3.

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Shima, Seigo, Michael Schick, and Haruka Tamura. "Preparation of [Fe]-Hydrogenase from Methanogenic Archaea." In Methods in Methane Metabolism, Part A. Elsevier, 2011. http://dx.doi.org/10.1016/b978-0-12-385112-3.00007-x.

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Srivastava, Jyoti, and Pradeep Srivastava. "Biomining Microorganisms' Molecular Aspects and Applications in Biotechnology and Bioremediation." In Biostimulation Remediation Technologies for Groundwater Contaminants. IGI Global, 2018. http://dx.doi.org/10.4018/978-1-5225-4162-2.ch001.

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The effective dissolution of metals is widely known with the help of microorganisms called bioleaching or biomining used for the extraction of metals from their ores. Usually the microorganisms involved in biomining are chemolithoautotrophic and extremophilic in nature, since they are living in highly acidic environments (pH 1-3.0) containing heavy concentrations of metals. The commonly found genera of archea are Sulfolobus, Acidianus, Metallosphaera, and Sulfurisphaera. Throughput microbial genomics and proteomics analysis provides novel insights of metabolism mechanisms of bioleaching microbes. These microbes are having significant impact on the bioremediation of acid mine drainage (AMD) resulted from many industrial operations. Using these microbes, various metals including Ni, Cd, Cu, Fe, As, Pb, Hg, Cr, Mn, Zn, etc. are removed from the environment. Biomining microorganisms are having significant applications in the biotechnological processes including extraction of gold from ores, extraction of nickel from low-grade sulfide ores, extraction of copper from chalcopyrite, etc.
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Singh Kainth, Harpreet, Deeksha Khandelwal, Ranjit Singh, Gurjeet Singh, and Sanjiv Puri. "Role of Trace Elements in Breast Cancer and Their Characterization Using X-Ray Fluorescence Techniques." In Trace Elements and Its Effects on Human Health and Disease [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.95491.

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Breast cancer is the most common serious disease that occurs in the human body. Trace elements have an important function in biological and metabolism processes including activation or inhibition of enzymatic reaction, reactive oxygen species (ROS), competition between trace elements and metal proteins for binding positions and modifications in the permeability of cellular membranes which influence carcinogenic processes. A significant association between the abnormal concentration of trace elements and breast cancer has been found in many studies using XRF techniques like energy dispersive X-ray fluorescence (EDXRF), particle induced X-ray emission (PIXE), total reflection X-ray fluorescence (TXRF), wavelength dispersive X-ray fluorescence (WDXRF) and synchrotron induced X-ray fluorescence (SRIXE). This chapter considers trace elements like Fe, Cu, Zn, Cr, Cl, Ca, P, S, K, Na, Mg, Se, As and Sr. from the standpoint of their role as either inhibitory or causative agents of breast cancer. XRF techniques and sample preparation methods for analysis of biological samples are also reviewed.
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Singh Kainth, Harpreet, Deeksha Khandelwal, Ranjit Singh, Gurjeet Singh, and Sanjiv Puri. "Role of Trace Elements in Breast Cancer and Their Characterization Using X-Ray Fluorescence Techniques." In Trace Elements and Their Effects on Human Health and Diseases. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.95491.

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Breast cancer is the most common serious disease that occurs in the human body. Trace elements have an important function in biological and metabolism processes including activation or inhibition of enzymatic reaction, reactive oxygen species (ROS), competition between trace elements and metal proteins for binding positions and modifications in the permeability of cellular membranes which influence carcinogenic processes. A significant association between the abnormal concentration of trace elements and breast cancer has been found in many studies using XRF techniques like energy dispersive X-ray fluorescence (EDXRF), particle induced X-ray emission (PIXE), total reflection X-ray fluorescence (TXRF), wavelength dispersive X-ray fluorescence (WDXRF) and synchrotron induced X-ray fluorescence (SRIXE). This chapter considers trace elements like Fe, Cu, Zn, Cr, Cl, Ca, P, S, K, Na, Mg, Se, As and Sr. from the standpoint of their role as either inhibitory or causative agents of breast cancer. XRF techniques and sample preparation methods for analysis of biological samples are also reviewed.
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Conference papers on the topic "Fe metabolism"

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Tong, Wing-Hang, Nunziata Maio, and Tracey A. Rouault. "Abstract B08: Metabolic adaption in inflammatory macrophages through the modulation of Fe-S cluster biogenesis factors." In Abstracts: AACR Special Conference: Metabolism and Cancer; June 7-10, 2015; Bellevue, WA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1557-3125.metca15-b08.

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Dai, Jing, Yunjing Luo, Yuanbin She, and Rugang Zhong. "Notice of Retraction: Metabolism of Phenanthrene in Peroxynitrite/Fe(III) Porphyrin System by HPLC-MS." In 2011 5th International Conference on Bioinformatics and Biomedical Engineering. IEEE, 2011. http://dx.doi.org/10.1109/icbbe.2011.5780236.

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Henak, Corinne R., Ashley L. Kapron, Andrew E. Anderson, et al. "Effects of Cartilage Constitutive Model on Specimen-Specific Validation and Predictions of Cartilage Mechanics in the Human Hip." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14132.

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The initiation and progression of hip osteoarthritis (OA) may be predicted by mechanical factors [1]. Contact stress (CS), maximum shear stress (MSS) at the osteochondral interface and first principal strain (FPS) at the articular surface have been identified as parameters that alter the physical integrity and metabolism of cartilage [1]. Although these parameters are difficult to measure in-vivo, they can be predicted using finite element (FE) models. However, the reliability of model predictions and the effects of model assumptions are largely unknown. Direct validation of FE models against
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Bevill, Scott L., Paul L. Briant, and Thomas P. Andriacchi. "Numerical and Experimental Analysis of Articular Chondrocyte Deformation: Calibration of a Multiscale Finite Element Model." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-175554.

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Mechanical loading of chondrocytes in isolation [1] and of articular cartilage in culture [2] has been reported to be a potent regulator of chondrocyte metabolism. Experimental studies have related tissue-level and cell-level strains in mechanically loaded cartilage explants [3], but cannot be readily extended to address more physiologic loading cases. Numerical models, which might address this need, have primarily been axisymmetric [4, 5] or two-dimensional [6] and have idealized chondrocyte geometry. Given the complexity of the mechanism of the load transfer between the tissue and cell, howe
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Nakahara, Kaito, Yusuke Morita, Yoshihiro Tomita, and Eiji Nakamachi. "Stress Evaluation of Articular Cartilage Chondrocyte Cell by Using Multi-Scale Finite Element Method and Smoothed Particle Hydrodynamics Method." In ASME 2016 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/imece2016-66416.

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The morphology and function of articular cartilage tissue is regenerated through the metabolic activity of cells stimulated by the mechanical loading. In this study, a biphasic multi-scale analyses scheme is adopted for stress evaluation occurred in the chondrocyte cell. The dynamic-explicit finite element (FE) method was employed for the solid phase and the smoothed particle hydrodynamics (SPH) method was used for the fluid phase. A macro-scale 3D human knee joint FE model was constructed based on magnetic resonance (MR) cross sectional images. Further, we derived the Representative volume el
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Cooper, Rebecca E., Jessica Finck, Rene Hoover, Clara S. Chan, and Kirsten Küsel. "Genomic Insights into the Metabolic Flexibility of the Acid-Tolerant Fe(II)-oxidizer Sideroxydans sp. CL21." In Goldschmidt2020. Geochemical Society, 2020. http://dx.doi.org/10.46427/gold2020.476.

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Rafikova, O., M. Niihori, C. A. Eccles, M. Vasilyev, and R. Rafikov. "Pulmonary Hypertension and Metabolic Disease in Rats with Human Mutation in Fe-S Cluster Scaffold Protein NFU1." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5870.

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Kamel, Hisham, Omar Harraz, and Tamer Attia. "Developing a Cost-Effective and Functional Prosthetic Foot for Below Knee Amputees Using Topology Optimization and 3D Printing." In ASME 2019 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/imece2019-10616.

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Abstract This paper presents the results of an investigative study on the development of an affordable and functional prosthetic foot for below knee amputees. A prototype was successfully manufactured using 3D printing technology. This continuously evolving technology enables the rapid production of prosthetics that are individually customized for each patient. Our prototype was developed after conducting a topology optimization study that interestingly converged to the shape of the biological human foot. Afterwards, a design was envisioned where a simple energy storage and release mechanism w
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Andaque, Gentil A., Olívia Pinho, J. Santos Baptista, Jacqueline Castelo Branco, and Elizabete Nunes. "The occurrence of accidents and injury in mining shift worker influenced by food intake, a short review." In 4th Symposium on Occupational Safety and Health. FEUP, 2021. http://dx.doi.org/10.24840/978-972-752-279-8_0065-0072.

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Introduction: Identifying factors that contribute to occupational accidents has been a general concern of companies in the present millennium. One of the factors identified is the quality and quantity of food, as well as meals times. In this context, the present systematic review aimed to identify how food intake influences the occurrence of accidents in shift work, with some focus, although not exclusive, on the mining industry. Methodology: The research-based literature was carried out in four electronic databases: Medline/PubMed, Science Direct, Scopus and Web of Science. Have been combined
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