Academic literature on the topic 'Fecal biomarker'

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Journal articles on the topic "Fecal biomarker"

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Kamel, Y. S. "Increased Fecal Calprotectin Levels in Crohn’s Disease Correlate with Elevated Serum Th1- and Th17-Associated Cytokines." American Journal of Clinical Pathology 154, Supplement_1 (2020): S119—S120. http://dx.doi.org/10.1093/ajcp/aqaa161.261.

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Abstract Introduction/Objective Patient-reported symptoms and endoscopic disease activity do not correlate well in Crohn’s disease (CD). This warrants the need for reliable biomarkers to early detect active intestinal inflammation. Currently, the fecal calprotectin level is the most commonly used biomarker for inflammatory activity in CD. However, the diagnostic accuracy of the fecal calprotectin level is not fully efficacious and diagnosis may be further improved by the identification of other biomarkers for active CD. Here, we studied the association of a variety of serum disease markers wit
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Fengming, Yi, and Wu Jianbing. "Biomarkers of Inflammatory Bowel Disease." Disease Markers 2014 (2014): 1–11. http://dx.doi.org/10.1155/2014/710915.

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Inflammatory bowel disease (IBD) is a chronic disease mostly involved with intestine with unknown etiology. Diagnosis, evaluation of severity, and prognosis are still present as challenges for physicians. An ideal biomarker with the characters such as simple, easy to perform, noninvasive or microinvasive, cheap, rapid, and reproducible is helpful for patients and clinicians. Currently biomarkers applied in clinic include CRP, ESR, pANCA, ASCA, and fecal calprotectin. However, they are far from ideal. Lots of studies are focused on seeking for ideal biomarker for IBD. Herein, the paper reviewed
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Schaebs, Franka S., Tanja E. Wolf, Verena Behringer, and Tobias Deschner. "Fecal thyroid hormones allow for the noninvasive monitoring of energy intake in capuchin monkeys." Journal of Endocrinology 231, no. 1 (2016): 1–10. http://dx.doi.org/10.1530/joe-16-0152.

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Measuring energetic condition of wild animals is of major importance in ecological research, as it is profoundly linked to fitness. However, noninvasive monitoring of energetic condition in wild-living animals is methodologically challenging. Measuring urinary C-peptide levels is a suitable method to noninvasively assess energy balance in wild-living animals. As collecting urine is not always feasible in the wild, it is essential to establish alternative biomarkers for other sample types to assess energy balance. Thyroid hormones (TH) are potential candidates as they are involved in the regula
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Yildiz, Alp, Huseyin Gobut, Sezai Leventoglu, et al. "Septin-9: a novel biomarker for colorectal cancer screening." International Surgery Journal 6, no. 2 (2019): 355. http://dx.doi.org/10.18203/2349-2902.isj20190382.

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Background: The gold standard method for the diagnosis of colorectal cancer is colonoscopy. However, colonoscopy has several limitations and complications. Moreover, fecal occult blood test and serum based tumor markers do lack the desired specificity and sensitivity. Therefore, a novel biomarker is needed for early detection of colorectal cancer. With this prospective randomised controlled study author’s aim was to evaluate the efficacy of Septin-9 on colorectal cancer screening.Methods: Septin-9 is a protein which is encoded by the SEPT9 gene. SEPT9 has been detected in the blood of colorect
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Wright, Emily K. "Calprotectin or Lactoferrin: Do They Help." Digestive Diseases 34, no. 1-2 (2016): 98–104. http://dx.doi.org/10.1159/000442935.

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Background: The diagnosis and monitoring of inflammatory bowel disease (IBD) has traditionally relied on clinical assessment, serum markers of inflammation and endoscopic examination. Fecal biomarkers such as calprotectin (FC) and lactoferrin (FL) are predominantly derived from neutrophils, are easily detectable in the feces and are now established as valuable markers of intestinal inflammation. In recent years, a ‘treat to target' concept has emerged for the management of IBD. Adequate control of inflammation in IBD at a biochemical level is quickly becoming an important target in IBD managem
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Bodelier, Alexander, Tim Van den Heuvel, Ingeborg Bovee-Oudenhoven, et al. "Fecal Pancreatitis-Associated Protein: A Novel Biomarker in IBD?" Gastroenterology 140, no. 5 (2011): S—423. http://dx.doi.org/10.1016/s0016-5085(11)61738-1.

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Jiang, Zhi-dong, Kevin Garey, Todd Lasco, and Herbert Dupont. "Fecal Calprotectin as a Biomarker for Clostridium Difficile Infection." American Journal of Gastroenterology 111 (October 2016): S67. http://dx.doi.org/10.14309/00000434-201610001-00141.

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Kato, Jun, Sakiko Hiraoka, Asuka Nakarai, Shiho Takashima, Toshihiro Inokuchi, and Masao Ichinose. "Fecal immunochemical test as a biomarker for inflammatory bowel diseases: can it rival fecal calprotectin?" Intestinal Research 14, no. 1 (2016): 5. http://dx.doi.org/10.5217/ir.2016.14.1.5.

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Hsieh, Heidi, Jeffrey Morin, Cyndi Filliettaz, Rao Varada, Shelby LaBarre, and Zaher Radi. "Fecal Lipocalin-2 as a Sensitive and Noninvasive Biomarker in the TNBS Crohn’s Inflammatory Bowel Disease Model." Toxicologic Pathology 44, no. 8 (2016): 1084–94. http://dx.doi.org/10.1177/0192623316665927.

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Colitis induced by 2,4,6-Trinitrobenzenesulfonic acid (TNBS) has been used as a model for Crohn’s disease (CD) of inflammatory bowel disease (IBD). Lipocalin-2 (Lcn-2) is an emerging and clinically relevant biomarker of IBD. We investigated the performance of serum and fecal Lcn-2 in the TNBS model of colitis. Female, 7-week-old, BALB/c mice were administered intrarectally phosphate-buffered saline/water or 30% ethanol (vehicle control groups) for 5 days or TNBS for 5 days followed by a 28-day recovery phase. Serum and fecal levels of Lcn-2 were quantified, and effects on body weight, clinical
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Jovanovic, Milan, Nevena Gajovic, Natasa Zdravkovic, et al. "Fecal Galectin-3: A New Promising Biomarker for Severity and Progression of Colorectal Carcinoma." Mediators of Inflammation 2018 (2018): 1–11. http://dx.doi.org/10.1155/2018/8031328.

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Background and Objectives. The aim of the study was to determine systemic and fecal values of galectin-3 and pro- and anti-inflammatory cytokines in patients with CRC and the relationship with clinicopathological aspects. Methods. Concentrations of galectin-3, TNF-α, TGF-β, IL-10, and IL-1β were analyzed in samples of blood and stool of 60 patients with CRC. Results. Systemic concentration of TNF-α was significantly lower in patients with severe diseases (advanced TNM stage, nuclear grade, and poor histological differentiation) as in patients with more progressive CRC (lymph and blood vessel i
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Dissertations / Theses on the topic "Fecal biomarker"

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DeLorenzo, Corrina J. "Evaluating the Use of Fecal Transthyretin as a Biomarker for Noninvasive Pregnancy Diagnosis in the Polar Bear (Ursus maritimus)." University of Cincinnati / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1504797886103351.

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Motamarri, Srinivas. "Development of a Neural Based Biomarker Forecasting Tool to Classify Recreational Water Quality." University of Cincinnati / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1291307369.

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Matus, García Mariana Guadalupe. "Analysis of fecal biomarkers to impact clinical care and public health." Thesis, Massachusetts Institute of Technology, 2018. http://hdl.handle.net/1721.1/119603.

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Thesis: Ph. D., Massachusetts Institute of Technology, Computational and Systems Biology Program, 2018.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>DNA sequencing and metabolomics technologies have accelerated the discovery of novel biomarkers in clinical samples. In this thesis, I explore the potential of fecal biomarkers to impact clinical and public health practice through non-invasive assessments. First, I highlight the potential of the gut microbiome to provide novel diagnostic and therapeutic targets. By analyzing the gut microbiome and metabolome
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Cheung, Joanna. "Amniotic fluid alkaline phosphatase as a biomarker of fetal growth and development." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=18295.

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The objectives of this study were to assess the concentration of alkaline phosphatase (ALP) and its isoenzymes (intestinal, liver/bone/kidney, placental) in 2nd trimester amniotic fluid (AF) and to establish whether total ALP or placental ALP were related to infant birth weight (BW) or gestational age (GA). 518 biobanked AF samples were analyzed using fluorometry to measure ALP concentrations. Analysis of variance showed that mothers giving birth to small-for-gestational-age infants had higher placental AF ALP concentration compared to those giving birth to appropriate-for-gestational-age infa
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Leeming, Rhys, and n/a. "Coprostanol and related sterols as tracers for feacal contamination in Australian aquatic environments." University of Canberra. School of Resource, Environmental & Heritage Sciences, 1996. http://erl.canberra.edu.au./public/adt-AUC20060816.172519.

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Pollution from human and animal faecal waste is a major cause of deteriorating water quality and increased nutrient loads in coastal and inland waterways. Management of this problem depends on knowing which sources of faecal matter are the cause and what is the degree and extent of the pollution. Bacterial indicator organisms have long been the principal method used to test water samples for faecal contamination. However, none of the currently used bacterial indicators on their own are source specific enough to distinguish different sources of faecal matter. The use of faecal sterol biomarkers
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Oliver, Reeba. "Changes in cord blood dendritic cells as biomarkers of fetal exposure to stressor stimuli." Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/25754.

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DCs are central to fetal defences and it was postulated that phenotypic changes on CBDCs in response to infectious/stressor stimuli could identify compromised fetuses. Investigations were performed on whole blood using monoclonal antibody labelling and flow cytometry. Functional studies included endocytosis of Dextran particles and MLR. Both plasmacytoid (HLA-DR+CD11c−) and myeloid (HLA-DR+CD11c+) DCs were identified in CB. Additionally CB contained a DC subset with a HLA-DR+CD11c−CD45^intermediate(inm) phenotype. This population expressed lower levels of CD45 and HLA-DR and did not express pl
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Cannon, Matthew. "Large-scale Investigation of Fetal Hemoglobin Modulators and Inflammation Biomarkers in Sickle Cell Disease." The Ohio State University, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=osu16188574420699.

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Higgins, Lucy. "Assessing and quantifying placental dysfunction in relation to pregnancy outcome in pregnancies complicated by reduced fetal movements." Thesis, University of Manchester, 2015. https://www.research.manchester.ac.uk/portal/en/theses/assessing-and-quantifying-placental-dysfunction-in-relation-to-pregnancy-outcome-in-pregnancies-complicated-by-reduced-fetal-movements(49311fd8-8b13-4741-8e60-e150be8765ee).html.

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Currently there is no test to accurately predict stillbirth. It is proposed that better identification of placental disease in utero may aid stillbirth prediction and prevention. Pregnancies complicated by reduced fetal movement (RFM) have increased risk of stillbirth. We hypothesised that RFM is a symptom of placental dysfunction associated with adverse pregnancy outcome (APO) and that this placental abnormality can be detected antenatally and used to identify fetuses at highest-risk of APO. We tested this hypothesis by: 1) comparison of ex vivo placental structure and function between APO RF
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El-Halabi, Dima. "Oxidative and nitrative stress biomarkers in amniotic fluid and their association with fetal growth and pregnancy outcomes." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=101119.

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The study objectives were to: (1) assess fetal exposure to oxidative stress by measuring amniotic fluid concentrations of nitric oxide (NO), thiobarbituric acid--reactive substances (TBARS), and ferric reducing antioxidant power (FRAP) and (2) establish whether these concentrations were associated with infant birth weight, gestational age, or oxidative stress-related conditions arising during pregnancy. Frozen amniotic fluid samples were obtained from 654 mothers undergoing amniocentesis for genetic testing during second trimester in Montreal, QC, Canada. Maternal and neonatal characteristics
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Papadopoulou, Eleni 1985. "Dietary exposure to persistent organic pollutants during pregnancy and child health." Doctoral thesis, Universitat Pompeu Fabra, 2013. http://hdl.handle.net/10803/116933.

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Introduction Diet is the main source of exposure to persistent organic pollutants (POPs), including dioxins and PCBs. During pregnancy the fetus is exposed to POPs which can lead to adverse health effects. The research hypothesis of this thesis is that maternal diet, as a source of prenatal exposure to POPs, may be linked to impaired fetal growth and endocrine disruptive effects. Methods This thesis included 604 mother-child pairs from the European NewGeneris project, 50,651 mother-child pairs from the Norwegian Mother and Child Cohort (MoBa) and 707 mother-child pairs from the Rhea and the
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Book chapters on the topic "Fecal biomarker"

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Evershed, Richard P., and Philip H. Bethell. "Application of Multimolecular Biomarker Techniques to the Identification of Fecal Material in Archaeological Soils and Sediments." In ACS Symposium Series. American Chemical Society, 1996. http://dx.doi.org/10.1021/bk-1996-0625.ch013.

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Damman, Jennifer, and K. T. Park. "Fecal Biomarkers in Inflammatory Bowel Disease." In Pediatric Inflammatory Bowel Disease. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-49215-5_19.

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Grangé, Gilles, Marie Clémence Leguy, Vassilis Tsatsaris, and Jean Guibourdenche. "Fetal Beta2-Microglobulin as a Biomarker of Kidney Disease." In Biomarkers in Kidney Disease. Springer Netherlands, 2016. http://dx.doi.org/10.1007/978-94-007-7699-9_21.

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Grangé, Gilles, Marie Clémence Leguy, Vassilis Tsatsaris, and Jean Guibourdenche. "Fetal Beta2-Microglobulin as a Biomarker of Kidney Disease." In Biomarkers in Kidney Disease. Springer Netherlands, 2015. http://dx.doi.org/10.1007/978-94-007-7743-9_21-1.

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Raczkowska, Beata Anna, Monika Zbucka-Kretowska, Adam Kretowski, and Michal Ciborowski. "Biomarkers of Abnormal Birth Weight in Pregnancy." In Diet, Nutrition, and Fetal Programming. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-60289-9_36.

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Menon, Ramkumar, Nathalia Noda Nicolau, Sarah Bredson, and Jossimara Polettini. "Fetal Membranes: Potential Source of Preterm Birth Biomarkers." In General Methods in Biomarker Research and their Applications. Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-007-7740-8_28-1.

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Menon, Ramkumar, Nathalia Noda Nicolau, Sarah Bredson, and Jossimara Polettini. "Fetal Membranes: Potential Source of Preterm Birth Biomarkers." In Biomarkers in Disease: Methods, Discoveries and Applications. Springer Netherlands, 2015. http://dx.doi.org/10.1007/978-94-007-7696-8_28.

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Fetit, Ahmed E., Siyamalan Manivannan, Sarah McGrory, et al. "Retinal Biomarker Discovery for Dementia in an Elderly Diabetic Population." In Fetal, Infant and Ophthalmic Medical Image Analysis. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-67561-9_17.

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"10. Biomarker for the detection of maternal alcohol use during pregnancy." In Fetal Alcohol Syndrome. De Gruyter, 2018. http://dx.doi.org/10.1515/9783110436563-010.

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Sitepu, Makmur, and Jusuf Rachmadsyah. "Risk Factor and Biomarker of Preeclampsia." In Prediction of Maternal and Fetal Syndrome of Preeclampsia. IntechOpen, 2019. http://dx.doi.org/10.5772/intechopen.85173.

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Conference papers on the topic "Fecal biomarker"

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Higano, N. S., X. Cao, J. Guo, et al. "Fetal Lung Development in Rhesus Macaques Using Quantitative Diffusion MRI and Histological Biomarkers." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6046.

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Amat-Roldan, I., S, Psilodimitrakopoulos, E, Eixarch, et al. "Myosin helical pitch angle as a quantitative imaging biomarker for characterization of cardiac programming in fetal growth restriction measured by polarization second harmonic microscopy." In European Conferences on Biomedical Optics, edited by Paul J. Campagnola, Ernst H. K. Stelzer, and Gert von Bally. SPIE, 2009. http://dx.doi.org/10.1117/12.831481.

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Reports on the topic "Fecal biomarker"

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Lyutakov, Ivan, Radislav Nakov, Borislav Vladimirov, et al. Diagnostic Accuracy and Predictive Value of Serum Fibroblast Growth Factor 19 (FGF19) and Total Free Fecal Bile Acids as Biomarkers of Bile Acid Malabsorption in Patients with Chronic Diarrhea: a Pilot Study. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, 2020. http://dx.doi.org/10.7546/crabs.2020.12.16.

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