Academic literature on the topic 'Felkin-Anh'

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Journal articles on the topic "Felkin-Anh"

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Rosenberg, Robert E., and W. Jonathan Kelly. "Felkin-Anh is not enough." Journal of Physical Organic Chemistry 28, no. 1 (November 27, 2014): 47–56. http://dx.doi.org/10.1002/poc.3397.

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Bailey, Constance B., Marjolein E. Pasman, and Adrian T. Keatinge-Clay. "Substrate structure–activity relationships guide rational engineering of modular polyketide synthase ketoreductases." Chemical Communications 52, no. 4 (2016): 792–95. http://dx.doi.org/10.1039/c5cc07315d.

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Structure–activity relationship studies guided stereocontrol engineering within a modular polyketide synthase ketoreductase to yield a more active enzyme whose reactivity can be explained through the Felkin–Anh model.
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Hein, S. J., and D. A. Keszler. "A product predicted with the Felkin–Anh model." Acta Crystallographica Section C Crystal Structure Communications 43, no. 12 (December 15, 1987): 2457–59. http://dx.doi.org/10.1107/s0108270187087365.

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Smith, Richard J., Michael Trzoss, Michael Bühl, and Stefan Bienz. "The Cram Rule Revisited Once More — Revision of the Felkin−Anh Model." European Journal of Organic Chemistry 2002, no. 16 (August 2002): 2770. http://dx.doi.org/10.1002/1099-0690(200208)2002:16<2770::aid-ejoc2770>3.0.co;2-x.

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Spino, Claude, Marie-Claude Granger, Luc Boisvert, and Christian Beaulieu. "Increased Felkin–Anh selectivity in nucleophilic additions to α-chiral aldehydes using vinylalanes." Tetrahedron Letters 43, no. 23 (June 2002): 4183–85. http://dx.doi.org/10.1016/s0040-4039(02)00753-0.

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Christoffers, Jens, Heiko Scharl, Wolfgang Frey, and Angelika Baro. "Transformation of an Optically Active Decahydro-6-isoquinolone Scaffold: Perfect Felkin−Anh Diastereoselectivity." Organic Letters 6, no. 7 (April 2004): 1171–73. http://dx.doi.org/10.1021/ol049831q.

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Shumway, William, Sihyun Ham, Jessica Moer, Bruce R. Whittlesey, and David M. Birney. "Felkin−Anh Stereoselectivity in Cycloadditions of Acetylketene: Evidence for a Concerted, Pseudopericyclic Pathway." Journal of Organic Chemistry 65, no. 23 (November 2000): 7731–39. http://dx.doi.org/10.1021/jo0002644.

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Myeong, In-Soo, Jin-Seok Kim, Muyng-Gyu Park, Hwan-Hee Jeon, Changyoung Jung, Yong-Taek Lee, and Won-Hun Ham. "Stereoselective Allylation of Linear and Chiral β-Amino-α-Hydroxy Aldehydes: Total Syntheses of Tetraacetyl d-lyxo-, d-ribo-, and d-arabino-Phytosphingosines." Synthesis 50, no. 10 (March 27, 2018): 2058–66. http://dx.doi.org/10.1055/s-0037-1609343.

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The stereoselective allylations of β-amino-α-hydroxy aldehydes­ are described. Several Lewis acids (BF3·OEt2, SnCl4, TiCl4, ZnCl2­, and MgBr2·OEt2) were utilized in the allylations. The allylation of anti-β-NHCbz-α-OTBS substrate mediated by SnCl4 afforded the syn-selective­ product, while its allylation mediated by BF3·OEt2 afforded the anti-selective product. The allylation of syn-β-NHCbz-α-OTBS mediated by SnCl4 afforded the anti-selective product. The mechanism involves the chelation between the amido group and aldehyde oxygen by SnCl4, and the Felkin–Anh model by BF3·OEt2. The resulting allylation products were used for the total syntheses of tetraacetyl d-lyxo-, d-ribo-, and d-arabino-phytosphingosines.
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Bubert, Christian, and Oliver Reiser. "Exceptionally high Felkin-Anh control for the addition of nucleophiles to a β-aminocyclopropylcarbaldehyde." Tetrahedron Letters 38, no. 28 (July 1997): 4985–88. http://dx.doi.org/10.1016/s0040-4039(97)01065-4.

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Giese, Bernd, Wolfgang Damm, Martin Roth, and Margaretha Zehnder. "The Felkin-Anh Rule in Radical Chemistry: 1,2-Stereoinduction in Radical Addition to Alkenes." Synlett 1992, no. 05 (1992): 441–43. http://dx.doi.org/10.1055/s-1992-21374.

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Dissertations / Theses on the topic "Felkin-Anh"

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Novikov, Yehor. "1-Bromo-1-lithioethene as a building block for organic synthesis." [Kent, Ohio] : Kent State University, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=kent1135388929.

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Thesis (Ph.D.)--Kent State University, 2005.
Title from PDF t.p. (viewed July 25, 2006). Advisor: Paul Sampson. Keywords: organolithiums, Felkin-Anh diastereoselectivity, low temperatures, cryogenic reactor, carbohydrates, building blocks. Includes bibliographical references (p. 186-197).
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Danielsson, Jakob. "Stereoselective Nucleophilic Additions to Aldehydes and Synthesis of α-Amino-β- Hydroxy-Esters." Licentiate thesis, KTH, Organisk kemi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-95467.

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This thesis deals with the development of new reaction methodology as well as stereochemical investigations. The first part concerns the investigation of 1,2- and merged 1,2- and 1,3- asymmetric induction in Mukaiyama aldol additions to α-heteroatom and α,β- heteroatom substituted aldehydes respectively. In particular, the unexpected 1,2-syn selectivity obtained in the addition of sterically hindered nucleophiles to α-chloroaldehydes is examined, and an explanation for the observed stereochemical trends is proposed. The second part describes the development of a novel entry to α-amino-β- hydroxy esters by a 1,3-dipolar cycloaddition reaction of aldehydes and azomethine ylides, generated by thermolysis of aziridines. The third part deals with our efforts to develop a novel entry to vicinal all- carbon quaternary centers, based on an intramolecular domino Heck- carbonylation reaction using tetrasubstituted olefins.
QC 20120611
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Godin, François. "Synthèse diastéréosélective du fragment C1-C13 de la zincophorine par approche combinée utilisant une séquence d'aldolisation de Mukaiyama suivie d'une réduction radicalaire." Thèse, 2008. http://hdl.handle.net/1866/7814.

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Brazeau, Jean-François. "Synthèse diastéréosélective des motifs polypropionate à partir des aldéhydes 2,3-syn via une séquence d'aldolisation de Mukaiyama suivie d'une réduction radicalaire contrôlées à l'aide d'acides de Lewis." Thèse, 2004. http://hdl.handle.net/1866/16750.

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Mochirian, Philippe. "Nouvelle méthodologie de synthèse de polypropionates dérivés d'un motif anti, anti : synthèses formelles de la zincophorine." Thèse, 2007. http://hdl.handle.net/1866/17998.

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Trinh, Nguyen Thu Thao. "Synthèse diastétéosélective de motifs 4-amino-3-hydroxy-2-méthylpentanoate de méthyle via une séquence impliquant une aldolisation de Mukaiyama et une réduction radicalaire à partir de dérivés d'acides [alpha]-aminés." Thèse, 2005. http://hdl.handle.net/1866/16776.

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